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Anthony Norman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Chickens

Disorders

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Molecular Structure

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Co-Publications
Name
35
Bishop, June
31
Okamura, William
26
Nemere, Ilka
13
Bula, Craig
11
Mizwicki, Mathew
10
Koeffler, Phillip
8
Henry, Helen
8
Zanello, Laura
7
Farach-Carson, Mary
6
Ishizuka, Seiichi
6
Olivera, Christopher
5
Muralidharan, KR
5
Uskokovic, Milan
3
Seo, EG
3
Song, X

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Publications

TOP 3
Deng Changhui; Ueda Eric; Chen Kuanhui E; Bula Craig; Norman Anthony W; Luben Richard A; Walker Ameae M
Prolactin blocks nuclear translocation of VDR by regulating its interaction with BRCA1 in osteosarcoma cells.
Mizwicki Mathew T; Norman Anthony W
The vitamin D sterol-vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling.
Norman Anthony W
A vitamin D nutritional cornucopia: new insights concerning the serum 25-hydroxyvitamin D status of the US population.

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All Publications

2009: Deng Changhui; Ueda Eric; Chen Kuanhui E; Bula Craig; Norman Anthony W; Luben Richard A; Walker Ameae M
Prolactin blocks nuclear translocation of VDR by regulating its interaction with BRCA1 in osteosarcoma cells.
Molecular endocrinology (Baltimore, Md.) 2009;23(2):226-36.
2009: Mizwicki Mathew T; Norman Anthony W
The vitamin D sterol-vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling.
Science signaling 2009;2(75):re4.
2008: Norman Anthony W
A vitamin D nutritional cornucopia: new insights concerning the serum 25-hydroxyvitamin D status of the US population.
The American journal of clinical nutrition 2008;88(6):1455-6.
2008: Norman Anthony W
From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health.
The American journal of clinical nutrition 2008;88(2):491S-499S.
2007: Bula Craig M; Bishop June E; Norman Anthony W
Conservative mutageneic perturbations of amino acids connecting helix 12 in the 1alpha,25(OH)2-D3 receptor (VDR) to the ligand cause significant transactivational effects.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):286-92.
2007: Mizwicki Mathew T; Bula Craig M; Bishop June E; Norman Anthony W
New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):243-62.
2007: Norman Anthony W; Bouillon Roger; Whiting Susan J; Vieth Reinhold; Lips Paul
13th Workshop consensus for vitamin D nutritional guidelines.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):204-5.
2007: Dixon K M; Deo S S; Norman A W; Bishop J E; Halliday G M; Reeve V E; Mason R S
In vivo relevance for photoprotection by the vitamin D rapid response pathway.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):451-6.
2006: Norman Anthony W
Minireview: vitamin D receptor: new assignments for an already busy receptor.
Endocrinology 2006;147(12):5542-8.
2005: Bula Craig M; Huhtakangas Johanna; Olivera Christopher; Bishop June E; Norman Anthony W; Henry Helen L
Presence of a truncated form of the vitamin D receptor (VDR) in a strain of VDR-knockout mice.
Endocrinology 2005;146(12):5581-6.
2005: Mizwicki Mathew T; Bula Craig M; Bishop June E; Norman Anthony W
A perspective on how the Vitamin D sterol/Vitamin D receptor (VDR) conformational ensemble model can potentially be used to understand the structure-function results of A-ring modified Vitamin D sterols.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):69-82.
2005: Dixon K M; Deo S S; Wong G; Slater M; Norman A W; Bishop J E; Posner G H; Ishizuka S; Halliday G M; Reeve V E; Mason R S
Skin cancer prevention: a possible role of 1,25dihydroxyvitamin D3 and its analogs.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):137-43.
2005: Mizwicki Mathew T; Bishop June E; Norman Anthony W
Applications of the Vitamin D sterol-Vitamin D receptor (VDR) conformational ensemble model.
Steroids 2005;70(5-7):464-71.
2005: Ochiai Eiji; Miura Daishiro; Eguchi Hiroshi; Ohara Sachiko; Takenouchi Kazuya; Azuma Yoshiaki; Kamimura Takashi; Norman Anthony W; Ishizuka Seiichi
Molecular mechanism of the vitamin D antagonistic actions of (23S)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone depends on the primary structure of the carboxyl-terminal region of the vitamin d receptor.
Molecular endocrinology (Baltimore, Md.) 2005;19(5):1147-57.
2005: Miura Daishiro; Norman Anthony W; Mizwicki Mathew T; Fujishima Toshie; Konno Katsuhiro; Kittaka Atsushi; Takayama Hiroaki; Ishizuka Seiichi
The antagonism between 2-methyl-1,25-dihydroxyvitamin D3 and 2-methyl-20-epi-1,25-dihydroxyvitamin D3 in non-genomic pathway-mediated biological responses induced by 1alpha,25-dihydroxyvitamin D3 assessed by NB4 cell differentiation.
The Journal of steroid biochemistry and molecular biology 2005;94(5):469-79.
2005: Vertino Anthony M; Bula Craig M; Chen Jin-Ran; Almeida Maria; Han Li; Bellido Teresita; Kousteni Stavroula; Norman Anthony W; Manolagas Stavros C
Nongenotropic, anti-apoptotic signaling of 1alpha,25(OH)2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes. Mediation by Src, phosphatidylinositol 3-, and JNK kinases.
The Journal of biological chemistry 2005;280(14):14130-7.
2005: Collins Elaine D; Bishop June E; Bula Craig M; Acevedo Alejandra; Okamura William H; Norman Anthony W
Effect of 25-hydroxyl group orientation on biological activity and binding to the 1alpha,25-dihydroxy vitamin D3 receptor.
The Journal of steroid biochemistry and molecular biology 2005;94(4):279-88.
2004: Huhtakangas Johanna A; Olivera Christopher J; Bishop June E; Zanello Laura P; Norman Anthony W
The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro.
Molecular endocrinology (Baltimore, Md.) 2004;18(11):2660-71.
2004: Mizwicki Mathew T; Keidel Don; Bula Craig M; Bishop June E; Zanello Laura P; Wurtz Jean-Marie; Moras Dino; Norman Anthony W
Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(35):12876-81.
2004: Zanello Laura P; Norman Anthony W
Electrical responses to 1alpha,25(OH)2-Vitamin D3 and their physiological significance in osteoblasts.
Steroids 2004;69(8-9):561-5.
2004: Wong G; Gupta R; Dixon K M; Deo S S; Choong S M; Halliday G M; Bishop J E; Ishizuka S; Norman A W; Posner G H; Mason R S
1,25-Dihydroxyvitamin D and three low-calcemic analogs decrease UV-induced DNA damage via the rapid response pathway.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):567-70.
2004: Olivera Christopher J; Bula Craig M; Bishop June E; Adorini Luciano; Manchand Percy; Uskokovic Milan R; Norman Anthony W
Characterization of five 19-nor-analogs of 1alpha,25(OH)2-Vitamin D3 with 20-cyclopropyl-modified side-chains: implications for ligand binding and calcemic properties.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):99-106.
2004: Weyts Franci A; Dhawan Puneet; Zhang Xiaoyu; Bishop June E; Uskokovic Milan R; Ji Yan; Studzinski George P; Norman Anthony W; Christakos Sylvia
Novel Gemini analogs of 1alpha,25-dihydroxyvitamin D(3) with enhanced transcriptional activity.
Biochemical pharmacology 2004;67(7):1327-36.
2004: Mizwicki Mathew T; Bishop June E; Olivera Christopher J; Huhtakangas Johanna; Norman Anthony W
Evidence that annexin II is not a putative membrane receptor for 1alpha,25(OH)2-vitamin D3.
Journal of cellular biochemistry 2004;91(4):852-63.
2004: Zanello Laura P; Norman Anthony W
Rapid modulation of osteoblast ion channel responses by 1alpha,25(OH)2-vitamin D3 requires the presence of a functional vitamin D nuclear receptor.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1589-94.
2004: Norman Anthony W; Mizwicki Mathew T; Norman Derek P G
Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model.
Nature reviews. Drug discovery 2004;3(1):27-41.
2003: Zanello Laura P; Norman Anthony W
Multiple molecular mechanisms of 1 alpha,25(OH)2-vitamin D3 rapid modulation of three ion channel activities in osteoblasts.
Bone 2003;33(1):71-9.
2003: Mizwicki Mathew T; Norman Anthony W
Two key proteins of the vitamin D endocrine system come into crystal clear focus: comparison of the X-ray structures of the nuclear receptor for 1alpha,25(OH)2 vitamin D3, the plasma vitamin D binding protein, and their ligands.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(5):795-806.
2003: Norman Anthony W; Mizwicki Mathew T; Okamura William H
Ligand structure-function relationships in the vitamin D endocrine system from the perspective of drug development (including cancer treatment).
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():55-82.
2002: Norman Anthony W; Okamura William H; Bishop June E; Henry Helen L
Update on biological actions of 1alpha,25(OH)2-vitamin D3 (rapid effects) and 24R,25(OH)2-vitamin D3.
Molecular and cellular endocrinology 2002;197(1-2):1-13.
2002: Norman Anthony W; Olivera Christopher J; Barreto Silva Fátima R M; Bishop June E
A specific binding protein/receptor for 1alpha,25-dihydroxyvitamin D(3) is present in an intestinal caveolae membrane fraction.
Biochemical and biophysical research communications 2002;298(3):414-9.
2002: Shi Hang; Norman Anthony W; Okamura William H; Sen Anindita; Zemel Michael B
1alpha,25-dihydroxyvitamin D3 inhibits uncoupling protein 2 expression in human adipocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1808-10.
2002: Norman Anthony W; Bishop June E; Bula Craig M; Olivera Christopher J; Mizwicki Mathew T; Zanello Laura P; Ishida Hitoshi; Okamura William H
Molecular tools for study of genomic and rapid signal transduction responses initiated by 1 alpha,25(OH)(2)-vitamin D(3).
Steroids 2002;67(6):457-66.
2002: Okamura William H; Zhu Gui-Dong; Hill David K; Thomas Richard J; Ringe Kerstin; Borchardt Daniel B; Norman Anthony W; Mueller Leonard J
Synthesis and NMR studies of (13)C-labeled vitamin D metabolites.
The Journal of organic chemistry 2002;67(5):1637-50.
2001: Shi H; Norman A W; Okamura W H; Sen A; Zemel M B
1alpha,25-Dihydroxyvitamin D3 modulates human adipocyte metabolism via nongenomic action.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2751-3.
2001: Norman A W; Silva F R
Structure function studies: identification of vitamin D analogs for the ligand-binding domains of important proteins in the vitamin D-endocrine system.
Reviews in endocrine & metabolic disorders 2001;2(2):229-38.
2001: Uskokovic M R; Norman A W; Manchand P S; Studzinski G P; Campbell M J; Koeffler H P; Takeuchi A; Siu-Caldera M L; Rao D S; Reddy G S
Highly active analogs of 1alpha,25-dihydroxyvitamin D(3) that resist metabolism through C-24 oxidation and C-3 epimerization pathways.
Steroids 2001;66(3-5):463-71.
2001: Okamura W H; Do S; Kim H; Jeganathan S; Vu T; Zhu G D; Norman A W
Conformationally restricted mimics of vitamin D rotamers.
Steroids 2001;66(3-5):239-47.
2001: Norman A W; Henry H L; Bishop J E; Song X D; Bula C; Okamura W H
Different shapes of the steroid hormone 1alpha,25(OH)(2)-vitamin D(3) act as agonists for two different receptors in the vitamin D endocrine system to mediate genomic and rapid responses.
Steroids 2001;66(3-5):147-58.
2001: Norman A W
On becoming a molecular endocrinologist.
Steroids 2001;66(3-5):129-36.
2001: Norman A W; Ishizuka S; Okamura W H
Ligands for the vitamin D endocrine system: different shapes function as agonists and antagonists for genomic and rapid response receptors or as a ligand for the plasma vitamin D binding protein.
The Journal of steroid biochemistry and molecular biology 2001;76(1-5):49-59.
2000: Bula C M; Bishop J E; Ishizuka S; Norman A W
25-Dehydro-1alpha-hydroxyvitamin D3-26,23S-lactone antagonizes the nuclear vitamin D receptor by mediating a unique noncovalent conformational change.
Molecular endocrinology (Baltimore, Md.) 2000;14(11):1788-96.
2000: Norman A W; Manchand P S; Uskokovic M R; Okamura W H; Takeuchi J A; Bishop J E; Hisatake J I; Koeffler H P; Peleg S
Characterization of a novel analogue of 1alpha,25(OH)(2)-vitamin D(3) with two side chains: interaction with its nuclear receptor and cellular actions.
Journal of medicinal chemistry 2000;43(14):2719-30.
1999: Norman A W; Adams D; Collins E D; Okamura W H; Fletterick R J
Three-dimensional model of the ligand binding domain of the nuclear receptor for 1alpha,25-dihydroxy-vitamin D(3).
Journal of cellular biochemistry 1999;74(3):323-33.
1999: Siu-Caldera M L; Sekimoto H; Weiskopf A; Vouros P; Muralidharan K R; Okamura W H; Bishop J; Norman A W; Uskokovic M R; Schuster I; Reddy G S
Production of 1alpha,25-dihydroxy-3-epi-vitamin D3 in two rat osteosarcoma cell lines (UMR 106 and ROS 17/2.8): existence of the C-3 epimerization pathway in ROS 17/2.8 cells in which the C-24 oxidation pathway is not expressed.
Bone 1999;24(5):457-63.
1999: Song X D; Norman A W
Bryostatin-1 and 1alpha,25-dihydroxyvitamin D3 synergistically stimulate the differentiation of NB4 acute promyelocytic leukemia cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(2):275-81.
1999: Norman A W; Song X; Zanello L; Bula C; Okamura W H
Rapid and genomic biological responses are mediated by different shapes of the agonist steroid hormone, 1alpha,25(OH)2vitamin D3.
Steroids 1999;64(1-2):120-8.
1999: Song X; Sheppard H M; Norman A W; Liu X
Mitogen-activated protein kinase is involved in the degradation of p53 protein in the bryostatin-1-induced differentiation of the acute promyelocytic leukemia NB4 cell line.
The Journal of biological chemistry 1999;274(3):1677-82.
1998: Kato A; Seo E G; Einhorn T A; Bishop J E; Norman A W
Studies on 24R,25-dihydroxyvitamin D3: evidence for a nonnuclear membrane receptor in the chick tibial fracture-healing callus.
Bone 1998;23(2):141-6.
1998: Kato A; Bishop J E; Norman A W
Evidence for a 1 alpha,25-dihydroxyvitamin D3 receptor/binding protein in a membrane fraction isolated from a chick tibial fracture-healing callus.
Biochemical and biophysical research communications 1998;244(3):724-7.
1998: Song X; Bishop J E; Okamura W H; Norman A W
Stimulation of phosphorylation of mitogen-activated protein kinase by 1alpha,25-dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: a structure-function study.
Endocrinology 1998;139(2):457-65.
1998: Song X; Norman A W
1Alpha,25-dihydroxyvitamin D3 and phorbol ester mediate the expression of alkaline phosphatase in NB4 acute promyelocytic leukemia cells.
Leukemia research 1998;22(1):69-76.
1997: Norman A W; Okamura W H; Hammond M W; Bishop J E; Dormanen M C; Bouillon R; van Baelen H; Ridall A L; Daane E; Khoury R; Farach-Carson M C
Comparison of 6-s-cis- and 6-s-trans-locked analogs of 1alpha,25-dihydroxyvitamin D3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred for genomic biological responses.
Molecular endocrinology (Baltimore, Md.) 1997;11(10):1518-31.
1997: Zanello L P; Norman A W
Stimulation by 1alpha,25(OH)2-vitamin D3 of whole cell chloride currents in osteoblastic ROS 17/2.8 cells. A structure-function study.
The Journal of biological chemistry 1997;272(36):22617-22.
1997: Seo E G; Einhorn T A; Norman A W
24R,25-dihydroxyvitamin D3: an essential vitamin D3 metabolite for both normal bone integrity and healing of tibial fracture in chicks.
Endocrinology 1997;138(9):3864-72.
1997: Muralidharan K R; Rowland-Goldsmith M; Lee A S; Park G; Norman A W; Henry H L; Okamura W H
Inhibitors of 25-hydroxyvitamin D3-1alpha-hydroxylase: thiavitamin D analogs and biological evaluation.
The Journal of steroid biochemistry and molecular biology 1997;62(1):73-8.
1997: Seo E G; Norman A W
Three-fold induction of renal 25-hydroxyvitamin D3-24-hydroxylase activity and increased serum 24,25-dihydroxyvitamin D3 levels are correlated with the healing process after chick tibial fracture.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(4):598-606.
1996: Seo E G; Kato A; Norman A W
Evidence for a 24R,25(OH)2-vitamin D3 receptor/binding protein in a membrane fraction isolated from a chick tibial fracture-healing callus.
Biochemical and biophysical research communications 1996;225(1):203-8.
1996: Zanello L P; Norman A W
1 alpha,25(OH)2 vitamin D3-mediated stimulation of outward anionic currents in osteoblast-like ROS 17/2.8 cells.
Biochemical and biophysical research communications 1996;225(2):551-6.
1996: Satchell D P; Norman A W
Metabolism of the cell differentiating agent 1alpha,25(OH)2-16-ene-23-yne vitamin D3 by leukemic cells.
The Journal of steroid biochemistry and molecular biology 1996;57(1-2):117-24.
1996: Norman A W; Bishop J E; Collins E D; Seo E G; Satchell D P; Dormanen M C; Zanello S B; Farach-Carson M C; Bouillon R; Okamura W H
Differing shapes of 1 alpha,25-dihydroxyvitamin D3 function as ligands for the D-binding protein, nuclear receptor and membrane receptor: a status report.
The Journal of steroid biochemistry and molecular biology 1996;56(1-6 Spec No):13-22.
1995: Chou S Y; Hannah S S; Lowe K E; Norman A W; Henry H L
Tissue-specific regulation by vitamin D status of nuclear and mitochondrial gene expression in kidney and intestine.
Endocrinology 1995;136(12):5520-6.
1995: Norman A W
Pleiotropic Actions of 1 alpha, 25-dihydroxyvitamin D3: an overview.
The Journal of nutrition 1995;125(6 Suppl):1687S-1689S.
1995: Zanello S B; Boland R L; Norman A W
cDNA sequence identity of a vitamin D-dependent calcium-binding protein in the chick to calbindin D-9K.
Endocrinology 1995;136(6):2784-7.
1995: Okamura W H; Midland M M; Hammond M W; Abd Rahman N; Dormanen M C; Nemere I; Norman A W
Chemistry and conformation of vitamin D molecules.
The Journal of steroid biochemistry and molecular biology 1995;53(1-6):603-13.
1995: Okamura W H; Midland M M; Norman A W; Hammond M W; Dormanen M C; Nemere I
Biochemical significance of the 6-s-cis conformation of the steroid hormone 1 alpha,25-dihydroxyvitamin D3 based on the provitamin D skeleton.
Annals of the New York Academy of Sciences 1995;761():344-8.
1995: Bouillon R; Okamura W H; Norman A W
Structure-function relationships in the vitamin D endocrine system.
Endocrine reviews 1995;16(2):200-57.
1995: Zhou L X; Norman A W
1 alpha,25(OH)2-vitamin D3 analog structure-function assessment of intestinal nuclear receptor occupancy with induction of calbindin-D28K.
Endocrinology 1995;136(3):1145-52.
1995: Norman A W
The vitamin D Endocrine system: manipulation of structure-function relationships to provide opportunities for development of new cancer chemopreventive and immunosuppressive agents.
Journal of cellular biochemistry. Supplement 1995;22():218-25.
1994: Khoury R; Ridall A L; Norman A W; Farach-Carson M C
Target gene activation by 1,25-dihydroxyvitamin D3 in osteosarcoma cells is independent of calcium influx.
Endocrinology 1994;135(6):2446-53.
1994: Hannah S S; Norman A W
1 alpha,25(OH)2 vitamin D3-regulated expression of the eukaryotic genome.
Nutrition reviews 1994;52(11):376-82.
1994: Nemere I; Dormanen M C; Hammond M W; Okamura W H; Norman A W
Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia.
The Journal of biological chemistry 1994;269(38):23750-6.
1994: Bishop J E; Collins E D; Okamura W H; Norman A W
Profile of ligand specificity of the vitamin D binding protein for 1 alpha,25-dihydroxyvitamin D3 and its analogs.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(8):1277-88.
1994: Maynard D F; Trankle W G; Norman A W; Okamura W H
14-epi stereoisomers of 25-hydroxy- and 1 alpha,25-dihydroxyvitamin D3: synthesis, isomerization to previtamins, and biological studies.
Journal of medicinal chemistry 1994;37(15):2387-93.
1994: Dormanen M C; Bishop J E; Hammond M W; Okamura W H; Nemere I; Norman A W
Nonnuclear effects of the steroid hormone 1 alpha,25(OH)2-vitamin D3: analogs are able to functionally differentiate between nuclear and membrane receptors.
Biochemical and biophysical research communications 1994;201(1):394-401.
1994: Norman A W; Collins E D
Correlation between vitamin D receptor allele and bone mineral density.
Nutrition reviews 1994;52(4):147-9.
1993: Farach-Carson M C; Abe J; Nishii Y; Khoury R; Wright G C; Norman A W
22-Oxacalcitriol: dissection of 1,25(OH)2D3 receptor-mediated and Ca2+ entry-stimulating pathways.
The American journal of physiology 1993;265(5 Pt 2):F705-11.
1993: Norman A W; Bouillon R; Farach-Carson M C; Bishop J E; Zhou L X; Nemere I; Zhao J; Muralidharan K R; Okamura W H
Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.
The Journal of biological chemistry 1993;268(27):20022-30.
1993: Norman A W; Sergeev I N; Bishop J E; Okamura W H
Selective biological response by target organs (intestine, kidney, and bone) to 1,25-dihydroxyvitamin D3 and two analogues.
Cancer research 1993;53(17):3935-42.
1993: Taoka T; Collins E D; Irino S; Norman A W
1,25(OH)2-vitamin D3 mediated changes in mRNA for c-myc and 1,25(OH)2D3 receptor in HL-60 cells and related subclones.
Molecular and cellular endocrinology 1993;95(1-2):51-7.
1993: Sundell K; Norman A W; Björnsson B T
1,25(OH)2 vitamin D3 increases ionized plasma calcium concentrations in the immature Atlantic cod Gadus morhua.
General and comparative endocrinology 1993;91(3):344-51.
1993: Norman A W; Okamura W H; Farach-Carson M C; Allewaert K; Branisteanu D; Nemere I; Muralidharan K R; Bouillon R
Structure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses.
The Journal of biological chemistry 1993;268(19):13811-9.
1993: Leathers V L; Norman A W
Evidence for calcium mediated conformational changes in calbindin-D28K (the vitamin D-induced calcium binding protein) interactions with chick intestinal brush border membrane alkaline phosphatase as studied via photoaffinity labeling techniques.
Journal of cellular biochemistry 1993;52(2):243-52.
1993: Norman A W; Hurwitz S
The role of the vitamin D endocrine system in avian bone biology.
The Journal of nutrition 1993;123(2 Suppl):310-6.
1993: Nemere I; Zhou L X; Norman A W
Nontranscriptional effects of steroid hormones.
Receptor 1993;3(4):277-91.
1992: Sergeev I N; Norman A W
Vitamin K-dependent gamma-carboxylation of the 1,25-dihydroxyvitamin D3 receptor.
Biochemical and biophysical research communications 1992;189(3):1543-7.
1992: Norman A W; Nemere I; Muralidharan K R; Okamura W H
1 beta, 25 (OH)2-vitamin D3 is an antagonist of 1 alpha,25 (OH)2-vitamin D3 stimulated transcaltachia (the rapid hormonal stimulation of intestinal calcium transport).
Biochemical and biophysical research communications 1992;189(3):1450-6.
1992: Sundell K; Bishop J E; Björnsson B T; Norman A W
1,25-Dihydroxyvitamin D3 in the Atlantic cod: plasma levels, a plasma binding component, and organ distribution of a high affinity receptor.
Endocrinology 1992;131(5):2279-86.
1992: Norman A W
Identification of a unique nuclear receptor for 9-cis retinoic acid.
Nutrition reviews 1992;50(8):230-1.
1992: Taoka T; Tasaka T; Tanaka T; Irino S; Norman A W
Characterization, growth, and differentiation of a human myeloid leukemia cell line, TI-1 cell.
Blood 1992;80(1):46-52.
1992: Nemere I; Opperman L A; Ross F P; Norman A W
Noncytoplasmic and filamentous appearance of calbindin-D28k and tubulin in double, indirect immunofluorescent staining of embryonic chick tissue.
Molecular and cellular endocrinology 1992;86(1-2):83-91.
1992: Zhou L X; Nemere I; Norman A W
A parathyroid-related peptide induces transcaltachia (the rapid, hormonal stimulation of intestinal Ca2+ transport).
Biochemical and biophysical research communications 1992;186(1):69-73.
1992: Norman A W
Bone biochemistry and physiology from the perspectives of the vitamin D endocrine system.
Current opinion in rheumatology 1992;4(3):375-82.
1992: Norman A W
Vitamin D research frontiers.
Journal of cellular biochemistry 1992;49(1):1-3.
1992: Lowe K E; Norman A W
Vitamin D and psoriasis.
Nutrition reviews 1992;50(5):138-42.
1992: Zhou L X; Nemere I; Norman A W
1,25-Dihydroxyvitamin D3 analog structure-function assessment of the rapid stimulation of intestinal calcium absorption (transcaltachia).
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(4):457-63.
1992: Cancela L; Ishida H; Bishop J E; Norman A W
Local chromatin changes accompany the expression of the calbindin-D28K gene: tissue specificity and effect of vitamin D activation.
Molecular endocrinology (Baltimore, Md.) 1992;6(3):468-75.
1992: Maiyar A C; Norman A W
Effects of sodium butyrate on 1,25-dihydroxyvitamin D3 receptor activity in primary chick kidney cells.
Molecular and cellular endocrinology 1992;84(1-2):99-107.
1992: Norman A W; Nemere I; Zhou L X; Bishop J E; Lowe K E; Maiyar A C; Collins E D; Taoka T; Sergeev I; Farach-Carson M C
1,25(OH)2-vitamin D3, a steroid hormone that produces biologic effects via both genomic and nongenomic pathways.
The Journal of steroid biochemistry and molecular biology 1992;41(3-8):231-40.
1992: Lowe K E; Maiyar A C; Norman A W
Vitamin D-mediated gene expression.
Critical reviews in eukaryotic gene expression 1992;2(1):65-109.
1991: Nemere I; Feld C; Norman A W
1,25-Dihydroxyvitamin D3-mediated alterations in microtubule proteins isolated from chick intestinal epithelium: analyses by isoelectric focusing.
Journal of cellular biochemistry 1991;47(4):369-79.
1991: Nemere I; Leathers V L; Thompson B S; Luben R A; Norman A W
Redistribution of calbindin-D28k in chick intestine in response to calcium transport.
Endocrinology 1991;129(6):2972-84.
1991: Farach-Carson M C; Sergeev I; Norman A W
Nongenomic actions of 1,25-dihydroxyvitamin D3 in rat osteosarcoma cells: structure-function studies using ligand analogs.
Endocrinology 1991;129(4):1876-84.
1991: Nemere I; Norman A W
Steroid hormone actions at the plasma membrane: induced calcium uptake and exocytotic events.
Molecular and cellular endocrinology 1991;80(1-3):C165-9.
1991: Figadère B; Norman A W; Henry H L; Koeffler H P; Zhou J Y; Okamura W H
Arocalciferols: synthesis and biological evaluation of aromatic side-chain analogues of 1 alpha,25-dihydroxyvitamin D3(1a).
Journal of medicinal chemistry 1991;34(8):2452-63.
1991: Zhou J Y; Norman A W; Akashi M; Chen D L; Uskokovic M R; Aurrecoechea J M; Dauben W G; Okamura W H; Koeffler H P
Development of a novel 1,25(OH)2-vitamin D3 analog with potent ability to induce HL-60 cell differentiation without modulating calcium metabolism.
Blood 1991;78(1):75-82.
1991: Nemere I; Norman A W
Redistribution of cathepsin B activity from the endosomal-lysosomal pathway in chick intestine within 3 min of calcium absorption.
Molecular and cellular endocrinology 1991;78(1-2):7-16.
1991: Maiyar A C; Minghetti P P; Norman A W
Transfection of avian vitamin D-dependent calbindin-D28K 5' flanking promoter sequence in primary chick kidney cells.
Molecular and cellular endocrinology 1991;78(1-2):127-35.
1991: Hall A K; Norman A W
Acute actions of 1,25-dihydroxyvitamin D3 upon chick pancreatic calbindin-D28K.
Biochemical and biophysical research communications 1991;176(3):1057-61.
1991: Kizaki M; Norman A W; Bishop J E; Lin C W; Karmakar A; Koeffler H P
1,25-Dihydroxyvitamin D3 receptor RNA: expression in hematopoietic cells.
Blood 1991;77(6):1238-47.
1991: Reichel H; Bishop J E; Koeffler H P; Norman A W
Evidence for 1,25-dihydroxyvitamin D3 production by cultured porcine alveolar macrophages.
Molecular and cellular endocrinology 1991;75(2):163-7.
1991: Boland R; Minghetti P P; Lowe K E; Norman A W
Sequences near the CCAAT region and putative 1,25-dihydroxyvitamin D3-response element and further upstream novel regulatory sequences of calbindin-D28k promoter show DNase I footprinting protection.
Molecular and cellular endocrinology 1991;75(1):57-63.
1991: Hall A K; Norman A W
Vitamin D-independent expression of chick brain calbindin-D28K.
Brain research. Molecular brain research 1991;9(1-2):9-14.
1990: Norman A W; Zhou J Y; Henry H L; Uskokovic M R; Koeffler H P
Structure-function studies on analogues of 1 alpha,25-dihydroxyvitamin D3: differential effects on leukemic cell growth, differentiation, and intestinal calcium absorption.
Cancer research 1990;50(21):6857-64.
1990: de Boland A R; Norman A W
Influx of extracellular calcium mediates 1,25-dihydroxyvitamin D3-dependent transcaltachia (the rapid stimulation of duodenal Ca2+ transport).
Endocrinology 1990;127(5):2475-80.
1990: Taoka T; Tokuda M; Tasaka T; Hatase O; Irino S; Norman A W
Induction of differentiation of HL-60 cells by protein kinase C inhibitor, K252a.
Biochemical and biophysical research communications 1990;170(3):1151-6.
1990: Taoka T; Norman A W
Vitamin D metabolism and nutrition.
Comprehensive therapy 1990;16(6):3-9.
1990: Leathers V L; Linse S; Forsén S; Norman A W
Calbindin-D28K, a 1 alpha,25-dihydroxyvitamin D3-induced calcium-binding protein, binds five or six Ca2+ ions with high affinity.
The Journal of biological chemistry 1990;265(17):9838-41.
1990: Zhou J Y; Norman A W; Chen D L; Sun G W; Uskokovic M; Koeffler H P
1,25-Dihydroxy-16-ene-23-yne-vitamin D3 prolongs survival time of leukemic mice.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3929-32.
1990: Hall A K; Norman A W
Regulation of calbindin-D28K gene expression in the chick intestine: effects of serum calcium status and 1,25-dihydroxyvitamin D3.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(4):331-6.
1990: Hall A K; Norman A W
Regulation of calbindin-D28K gene expression by 1,25-dihydroxyvitamin D3 in chick kidney.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(4):325-30.
1990: Koeffler H P; Bishop J E; Reichel H; Singer F; Nagler A; Tobler A; Walka M; Norman A W
Lymphocyte cell lines from vitamin D-dependent rickets type II show functional defects in the 1 alpha,25-dihydroxyvitamin D3 receptor.
Molecular and cellular endocrinology 1990;70(1):1-11.
1990: de Boland A R; Nemere I; Norman A W
Ca2(+)-channel agonist BAY K8644 mimics 1,25(OH)2-vitamin D3 rapid enhancement of Ca2+ transport in chick perfused duodenum.
Biochemical and biophysical research communications 1990;166(1):217-22.
1990: Nemere I; Norman A W
Transcaltachia, vesicular calcium transport, and microtubule-associated calbindin-D28K: emerging views of 1,25-dihydroxyvitamin D3-mediated intestinal calcium absorption.
Mineral and electrolyte metabolism 1990;16(2-3):109-14.
1990: Norman A W
The avian as an animal model for the study of the vitamin D endocrine system.
The Journal of experimental zoology. Supplement : published under auspices of the American Society of Zoologists and the Division of Comparative Physiology and Biochemistry / the Wistar Institute of Anatomy and Biology 1990;4():37-45.
1989: Nemere I; Norman A W
1,25-Dihydroxyvitamin D3-mediated vesicular calcium transport in intestine: dose-response studies.
Molecular and cellular endocrinology 1989;67(1):47-53.
1989: Zhou J Y; Norman A W; Lübbert M; Collins E D; Uskokovic M R; Koeffler H P
Novel vitamin D analogs that modulate leukemic cell growth and differentiation with little effect on either intestinal calcium absorption or bone mobilization.
Blood 1989;74(1):82-93.
1989: Minghetti P P; Gibbs P E; Norman A W
Computer analysis of 1,25-dihydroxyvitamin D3-receptor regulated promoters: identification of a candidate D3-response element.
Biochemical and biophysical research communications 1989;162(2):869-75.
1988: Ishida H; Norman A W
Demonstration of a high affinity receptor for 1,25-dihydroxyvitamin D3 in rat pancreas.
Molecular and cellular endocrinology 1988;60(2-3):109-17.
1988: Minghetti P P; Norman A W
1,25(OH)2-vitamin D3 receptors: gene regulation and genetic circuitry.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(15):3043-53.
1988: Nemere I; Norman A W
1,25-Dihydroxyvitamin D3-mediated vesicular transport of calcium in intestine: time-course studies.
Endocrinology 1988;122(6):2962-9.
1988: Tobler A; Miller C W; Norman A W; Koeffler H P
1,25-Dihydroxyvitamin D3 modulates the expression of a lymphokine (granulocyte-macrophage colony-stimulating factor) posttranscriptionally.
The Journal of clinical investigation 1988;81(6):1819-23.
1988: Ishida H; Cunningham N S; Henry H L; Norman A W
The number of 1,25-dihydroxyvitamin D3 receptors is decreased in both intestine and kidney of genetically diabetic db/db mice.
Endocrinology 1988;122(6):2436-43.
1988: Minghetti P P; Cancela L; Fujisawa Y; Theofan G; Norman A W
Molecular structure of the chicken vitamin D-induced calbindin-D28K gene reveals eleven exons, six Ca2+-binding domains, and numerous promoter regulatory elements.
Molecular endocrinology (Baltimore, Md.) 1988;2(4):355-67.
1988: Hall A K; Reichel H; Norman A W
Differential effects of 1,25-dihydroxyvitamin D3 upon intestinal vitamin D3-dependent calbindin (a 28,000-dalton calcium binding protein) and its mRNA in D-replete and D-deficient chickens.
Archives of biochemistry and biophysics 1988;260(2):645-52.
1988: Cancela L; Nemere I; Norman A W
1 alpha,25(OH)2 vitamin D3: a steroid hormone capable of producing pleiotropic receptor-mediated biological responses by both genomic and nongenomic mechanisms.
Journal of steroid biochemistry 1988;30(1-6):33-9.
1987: Theofan G; King M W; Hall A K; Norman A W
Expression of calbindin-D28K mRNA as a function of altered serum calcium and phosphorus levels in vitamin D-replete chick intestine.
Molecular and cellular endocrinology 1987;54(2-3):135-40.
1987: Reichel H; Koeffler H P; Barbers R; Norman A W
Regulation of 1,25-dihydroxyvitamin D3 production by cultured alveolar macrophages from normal human donors and from patients with pulmonary sarcoidosis.
The Journal of clinical endocrinology and metabolism 1987;65(6):1201-9.
1987: Nemere I; Theofan G; Norman A W
1,25-Dihydroxyvitamin D3 regulates tubulin expression in chick intestine.
Biochemical and biophysical research communications 1987;148(3):1270-6.
1987: Jongen M J; Bishop J E; Cade C; Norman A W
Effect of dietary calcium, phosphate and vitamin D deprivation on the pharmacokinetics of 1,25-dihydroxyvitamin D3 in the rat.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1987;19(10):481-5.
1987: Nemere I; Norman A W
Rapid action of 1,25-dihydroxyvitamin D3 on calcium transport in perfused chick duodenum: effect of inhibitors.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1987;2(2):99-107.
1986: Nemere I; Leathers V; Norman A W
1,25-Dihydroxyvitamin D3-mediated intestinal calcium transport. Biochemical identification of lysosomes containing calcium and calcium-binding protein (calbindin-D28K).
The Journal of biological chemistry 1986;261(34):16106-14.
1986: Putkey J A; Nemere I; Norman A W
Vitamin D status and brush border membrane vesicles: 1,25-dihydroxyvitamin D3 induced destabilization.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986;1(4):305-11.
1986: Ittel T H; Ross F P; Norman A W
Activity of ornithine decarboxylase and creatine kinase in soft and hard tissue of vitamin D-deficient chicks following parenteral application of 1,25-dihydroxyvitamin D3 or 24R,25-dihydroxyvitamin D3.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986;1(1):23-31.
1983: Nemere I; Putkey J A; Norman A W
Vitamin D-mediated alterations in the topography of intestinal brush border proteins: effect of papain on hydrolase release and calcium uptake.
Archives of biochemistry and biophysics 1983;222(2):610-20.
1982: Norman A W; Putkey J A; Nemere I
Intestinal calcium transport: pleiotropic effects mediated by vitamin D.
Federation proceedings 1982;41(1):78-83.

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