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Nicola Normanno

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Chemicals & Drugs

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Mouse

Physiology

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Tumor Cells, Cultured

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Giuseppe Pirozzi; G Scognamiglio; V Tirino; R Camerlingo; Monica Cantile; renato franco; Antonello La Rocca; N Martucci; Nicola Normanno; Gaetano Rocco
Prognostic value of cancer stem cells, epithelial-mesenchymal transition and circulating tumor cells in lung cancer.
Renato Franco; Amalia Luce; Federica Zito Marino; Alessandro Morabito; Nicola Normanno; Giuseppe Pirozzi; Gaetano Rocco; Pasquale Sperlongano; Paola Stiuso; Gerardo Botti; Michele Caraglia
Anaplastic lymphoma kinase: a glimmer of hope in lung cancer treatment?
Alessandro Morabito; Nicola Normanno; Raffaella Pasquale; Simona Bevilacqua; Gerardo Botti; Corradina Caraco; Antonietta Caronna; R Costanzo; Elisabetta De Lutio; Agnese Montanino; C Sandomenico; Gaetano Rocco
Positron emission tomography and circulating tumor cells to monitor a dramatic response to gefitinib.

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All Publications

2013: Giuseppe Pirozzi; G Scognamiglio; V Tirino; R Camerlingo; Monica Cantile; renato franco; Antonello La Rocca; N Martucci; Nicola Normanno; Gaetano Rocco
Prognostic value of cancer stem cells, epithelial-mesenchymal transition and circulating tumor cells in lung cancer.
Oncology reports 2013;29(5):1763-8.
2013: Renato Franco; Amalia Luce; Federica Zito Marino; Alessandro Morabito; Nicola Normanno; Giuseppe Pirozzi; Gaetano Rocco; Pasquale Sperlongano; Paola Stiuso; Gerardo Botti; Michele Caraglia
Anaplastic lymphoma kinase: a glimmer of hope in lung cancer treatment?
Expert review of anticancer therapy 2013;13(4):407-20.
2012: Alessandro Morabito; Nicola Normanno; Raffaella Pasquale; Simona Bevilacqua; Gerardo Botti; Corradina Caraco; Antonietta Caronna; R Costanzo; Elisabetta De Lutio; Agnese Montanino; C Sandomenico; Gaetano Rocco
Positron emission tomography and circulating tumor cells to monitor a dramatic response to gefitinib.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(11):e27-8.
2012: M Gallo; L Lamura; A De Luca; Nicola Normanno
Zoledronic acid blocks the interaction between mesenchymal stem cells and breast cancer cells: implications for adjuvant therapy of breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(3):597-604.
2012: Guido Carillio; Raffaele Costanzo; Gennaro Daniele; Massimo Di Maio; Pasqualina Giordano; Agnese Montanino; Nicola Normanno; Francesco Perrone; Maria Carmela Piccirillo; Gaetano Rocco; C Sandomenico; Jane Bryce; Alessandro Morabito
Cetuximab in non-small-cell lung cancer.
Expert review of anticancer therapy 2012;12(2):163-75.
2012: C Sandomenico; Guido Carillio; R Costanzo; Massimo Di Maio; A Montanino; Nicola Normanno; Francesco Perrone; M C Piccirillo; Gaetano Rocco; Alessandro Morabito
Bevacizumab in non small cell lung cancer: development, current status and issues.
Current medicinal chemistry 2012;19(7):961-71.
2011: Loredana Vecchione; Fortunato Ciardiello; Bart Jacobs; Nicola Normanno; Sabine Tejpar
EGFR-targeted therapy.
Experimental cell research 2011;317(19):2765-71.
2011: Fortunato Ciardiello; Nicola Normanno
HER2 signaling and resistance to the anti-EGFR monoclonal antibody cetuximab: a further step toward personalized medicine for patients with colorectal cancer.
Cancer discovery 2011;1(6):472-4.
2011: Fortunato Ciardiello; Domenica Mercadante; Nicola Normanno; Tracey Teague; Sabine Tejpar; Bruno Wohlschlegel; Eric Van Cutsem
Uptake of KRAS mutation testing in patients with metastatic colorectal cancer in Europe, Latin America and Asia.
Targeted oncology 2011;6(3):133-45.
2011: Gennaro Daniele; Pasqualina Giordano; Antonella De Luca; Maria Carmela Piccirillo; Massimo Di Maio; Antonia Del Giudice; Gianfranco De Feo; Jane Bryce; Luana Lamura; Aldo Vecchione; Nicola Normanno; Francesco Perrone
Anticancer effect of bisphosphonates: new insights from clinical trials and preclinical evidence.
Expert review of anticancer therapy 2011;11(2):299-307.
2011: Giuseppe Pirozzi; Virginia Tirino; Rosa Camerlingo; renato franco; Antonello La Rocca; Eleonora Liguori; Nicola Martucci; Nicola Normanno; Francesca Paino; Gaetano Rocco
Epithelial to mesenchymal transition by TGFβ-1 induction increases stemness characteristics in primary non small cell lung cancer cell line.
PloS one 2011;6(6):e21548.
2011: R Costanzo; Gennaro Daniele; Gianfranco De Feo; Massimo Di Maio; Pasqualina Giordano; Agnese Montanino; Nicola Normanno; Francesco Perrone; Maria Carmela Piccirillo; Gaetano Rocco; C Sandomenico; Jane Bryce; Guido Carillio; Alessandro Morabito
Gefitinib in non small cell lung cancer.
Journal of biomedicine & biotechnology 2011;2011():815269.
2010: Massimo Di Maio; Alessandro Morabito; Maria Carmela Piccirillo; Gennaro Daniele; Pasqualina Giordano; R Costanzo; Marita Georgia Riccardi; Gaetano Rocco; Nicola Normanno; Francesco Perrone
New drugs in advanced non-small-cell lung cancer: searching for the correct clinical development.
Expert opinion on investigational drugs 2010;19(12):1503-14.
2010: Alessandro Morabito; M C Piccirillo; R Costanzo; C Sandomenico; Guido Carillio; G Daniele; P Giordano; J Bryce; P Carotenuto; Antonello La Rocca; Massimo Di Maio; Nicola Normanno; Gaetano Rocco; Francesco Perrone
Vandetanib: An overview of its clinical development in NSCLC and other tumors.
Drugs of today (Barcelona, Spain : 1998) 2010;46(9):683-98.
2009: Mario Mancino; Claudia Esposito; Kazuhide Watanabe; Tadahiro Nagaoka; Monica Gonzales; Caterina Bianco; Nicola Normanno; David S Salomon; Luigi Strizzi
Neuronal guidance protein Netrin-1 induces differentiation in human embryonal carcinoma cells.
Cancer research 2009;69(5):1717-21.
2008: Donatella Cirillo; Anna Maria Rachiglio; Raffaele la Montagna; Antonio Giordano; Nicola Normanno
Leptin signaling in breast cancer: an overview.
Journal of cellular biochemistry 2008;105(4):956-64.
2008: Nicola Normanno; Manuela Campiglio; Monica R Maiello; Antonella De Luca; Mario Mancino; Marianna Gallo; Amelia D'Alessio; Sylvie Menard
Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling.
Breast cancer research and treatment 2008;112(1):25-33.
2008: Germano Zampa; Michele Moscato; Brian W Brannigan; Alessandro Morabito; Daphne W Bell; Nicola Normanno
Prolonged control of bone metastases in non-small-cell lung cancer patients treated with gefitinib.
Lung cancer (Amsterdam, Netherlands) 2008;60(3):452-4.
2008: David Garfield; Jacques Cadranel; Nicola Normanno
Osteoblastic metastases in non-small cell lung cancer and its possible significance.
Lung cancer (Amsterdam, Netherlands) 2008;60(1):146-7.
2008: Mario Mancino; Luigi Strizzi; Christian Wechselberger; Kazuhide Watanabe; Monica Gonzales; Shin Hamada; Nicola Normanno; David S Salomon; Caterina Bianco
Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells.
Journal of cellular physiology 2008;215(1):192-203.
2008: Antonella De Luca; Adele Carotenuto; Annamaria Rachiglio; Marianna Gallo; Monica R Maiello; Donatella Aldinucci; Antonio Pinto; Nicola Normanno
The role of the EGFR signaling in tumor microenvironment.
Journal of cellular physiology 2008;214(3):559-67.
2008: Caterina Bianco; Luigi Strizzi; Mario Mancino; Kazuhide Watanabe; Monica Gonzales; Shin Hamada; Ahmed Raafat; Lawson Sahlah; Cindy Chang; Federica Sotgia; Nicola Normanno; Michael Lisanti; David S Salomon
Regulation of Cripto-1 signaling and biological activity by caveolin-1 in mammary epithelial cells.
The American journal of pathology 2008;172(2):345-57.
2007: Alessandro Ottaiano; Alfredo Budillon; Nicola Normanno; Vincenzo Rosario Iaffaioli; M Caraglia
A multidisciplinary approach is required to increase the quality of phase II/III clinical studies on biotherapies in oncology.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(5):960-1.
2007: Monica R Maiello; Amelia D'Alessio; Antonella De Luca; Adele Carotenuto; Anna Maria Rachiglio; Maria Napolitano; Letizia Cito; Antonella Guzzo; Nicola Normanno
AZD3409 inhibits the growth of breast cancer cells with intrinsic resistance to the EGFR tyrosine kinase inhibitor gefitinib.
Breast cancer research and treatment 2007;102(3):275-82.
2007: Luigi Strizzi; Caterina Bianco; Morihisa Hirota; Kazuhide Watanabe; Mario Mancino; Shin Hamada; Ahmed Raafat; S Lawson; Andreas Ebert; Antonio D'Antonio; Simona Losito; Nicola Normanno; David S Salomon
Development of leiomyosarcoma of the uterus in MMTV-CR-1 transgenic mice.
The Journal of pathology 2007;211(1):36-44.
2006: Caterina Bianco; Luigi Strizzi; Mario Mancino; Aasia Rehman; Shin Hamada; Kazuhide Watanabe; Antonella De Luca; Brenda Jones; Gabriela A Balogh; Jose Russo; Daniel Mailo; Raffaele Palaia; Giuseppe D'Aiuto; Gerardo Botti; Francesco Perrone; David S Salomon; Nicola Normanno
Identification of cripto-1 as a novel serologic marker for breast and colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(17):5158-64.
2006: Alessandro Morabito; Ermelinda De Maio; Massimo Di Maio; Nicola Normanno; Francesco Perrone
Tyrosine kinase inhibitors of vascular endothelial growth factor receptors in clinical trials: current status and future directions.
The oncologist 2006;11(7):753-64.
2006: Alessandro Morabito; Massimo Di Maio; Ermelinda De Maio; Nicola Normanno; Francesco Perrone
Methodology of clinical trials with new molecular-targeted agents: where do we stand?
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17 Suppl 7():vii128-31.
2006: Nicola Normanno; Antonella De Luca; Monica R Maiello; Manuela Campiglio; Maria Napolitano; Mario Mancino; Adele Carotenuto; Giuseppe Viglietto; Sylvie Menard
The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib.
Journal of cellular physiology 2006;207(2):420-7.
2006: Nicola Normanno; William J Gullick
Epidermal growth factor receptor tyrosine kinase inhibitors and bone metastases: different mechanisms of action for a novel therapeutic application?
Endocrine-related cancer 2006;13(1):3-6.
2006: Nicola Normanno; Antonella De Luca; Caterina Bianco; Luigi Strizzi; Mario Mancino; Monica R Maiello; Adele Carotenuto; Gianfranco De Feo; Francesco Caponigro; David S Salomon
Epidermal growth factor receptor (EGFR) signaling in cancer.
Gene 2006;366(1):2-16.
2005: Nicola Normanno; Massimo Di Maio; Ermelinda De Maio; Antonella De Luca; Andrea de Matteis; Antonio Giordano; Francesco Perrone
Mechanisms of endocrine resistance and novel therapeutic strategies in breast cancer.
Endocrine-related cancer 2005;12(4):721-47.
2005: Massimo Di Maio; Cesare Gridelli; Nicola Normanno; Francesco Perrone; Fortunato Ciardiello
Trying to compose the puzzle with all the pieces: epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer.
Journal of cellular physiology 2005;205(3):355-63.
2005: Nicola Normanno; Antonella De Luca; Monica R Maiello; Cesare Gridelli
Modulation of epidermal growth factor receptor-positive circulating tumor cells by chemotherapy in non-small-cell lung cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(30):7746-8; author reply 7748.
2005: Luigi Strizzi; Caterina Bianco; Ahmed Raafat; Wissam Abdallah; Cindy Chang; Dina Raafat; Morihisa Hirota; Shin Hamada; Youping Sun; Nicola Normanno; Robert Callahan; Lindsay Hinck; David Salomon
Netrin-1 regulates invasion and migration of mouse mammary epithelial cells overexpressing Cripto-1 in vitro and in vivo.
Journal of cell science 2005;118(Pt 20):4633-43.
2005: Nicola Normanno; Manuela Campiglio; F Perrone; A De Luca; S Menard
Is the gefitinib plus trastuzumab combination feasible in breast cancer patients?
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(10):1709.
2005: Luigi Strizzi; Caterina Bianco; Nicola Normanno; David Salomon
Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis.
Oncogene 2005;24(37):5731-41.
2005: Christian Wechselberger; Luigi Strizzi; Nicholas Kenney; Morihisa Hirota; Youping Sun; Andreas Ebert; Olivia Orozco; Caterina Bianco; Nadia I Khan; Brenda Wallace-Jones; Nicola Normanno; Heather B Adkins; Michele Sanicola; David S Salomon
Human Cripto-1 overexpression in the mouse mammary gland results in the development of hyperplasia and adenocarcinoma.
Oncogene 2005;24(25):4094-105.
2005: Nicola Normanno; Antonella De Luca; Donatella Aldinucci; Monica R Maiello; Mario Mancino; Antonio D'Antonio; R De Filippi; A Pinto
Gefitinib inhibits the ability of human bone marrow stromal cells to induce osteoclast differentiation: implications for the pathogenesis and treatment of bone metastasis.
Endocrine-related cancer 2005;12(2):471-82.
2005: Nicola Normanno; Caterina Bianco; Luigi Strizzi; Mario Mancino; Monica R Maiello; Antonella De Luca; Francesco Caponigro; David S Salomon
The ErbB receptors and their ligands in cancer: an overview.
Current drug targets 2005;6(3):243-57.
2005: Francesco Caponigro; Roberta Formato; Michele Caraglia; Nicola Normanno; Rosario Vincenzo Iaffaioli
Monoclonal antibodies targeting epidermal growth factor receptor and vascular endothelial growth factor with a focus on head and neck tumors.
Current opinion in oncology 2005;17(3):212-7.
2005: Francesco Perrone; Massimo Di Maio; Alfredo Budillon; Nicola Normanno
Targeted therapies and non-small cell lung cancer: methodological and conceptual challenge for clinical trials.
Current opinion in oncology 2005;17(2):123-9.
2005: Francesco Caponigro; Maria Basile; Vincenzo De Rosa; Nicola Normanno
New drugs in cancer therapy, National Tumor Institute, Naples, 17-18 June 2004.
Anti-cancer drugs 2005;16(2):211-21.
2005: Caterina Bianco; Luigi Strizzi; Andreas Ebert; Cindy Chang; Aasia Rehman; Nicola Normanno; Liliana Guedez; Rita Salloum; Erika Ginsburg; Youping Sun; Nadia Khan; Morihisa Hirota; Brenda Wallace-Jones; Christian Wechselberger; Barbara K Vonderhaar; Giovanna Tosato; William Stetler-Stevenson; Michele Sanicola; David S Salomon
Role of human cripto-1 in tumor angiogenesis.
Journal of the National Cancer Institute 2005;97(2):132-41.
2005: Nicola Normanno; Antonella De Luca; Monica R Maiello; Mario Mancino; Antonio D'Antonio; Marcella Macaluso; Francesco Caponigro; Antonio Giordano
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in breast cancer: current status and future development.
Frontiers in bioscience : a journal and virtual library 2005;10():2611-7.
2005: Caterina Bianco; Luigi Strizzi; Nicola Normanno; Nadia Khan; David S Salomon
Cripto-1: an oncofetal gene with many faces.
Current topics in developmental biology 2005;67():85-133.
2004: Nicola Normanno; Monica R Maiello; Mario Mancino; Antonella De Luca
Small molecule epidermal growth factor receptor tyrosine kinase inhibitors: an overview.
Journal of chemotherapy (Florence, Italy) 2004;16 Suppl 4():36-40.
2004: Luigi Strizzi; Caterina Bianco; Nicola Normanno; Masaharu Seno; Christian Wechselberger; Brenda Wallace-Jones; Nadia I Khan; Morihisa Hirota; Youping Sun; Michele Sanicola; David S Salomon
Epithelial mesenchymal transition is a characteristic of hyperplasias and tumors in mammary gland from MMTV-Cripto-1 transgenic mice.
Journal of cellular physiology 2004;201(2):266-76.
2004: Nicola Normanno; Antonella De Luca; Monica R Maiello; Caterina Bianco; Mario Mancino; Luigi Strizzi; Claudio Arra; Fortunato Ciardiello; Sudhir Agrawal; David S Salomon
CRIPTO-1: a novel target for therapeutic intervention in human carcinoma.
International journal of oncology 2004;25(4):1013-20.
2004: Caterina Bianco; Nicola Normanno; David S Salomon; Fortunato Ciardiello
Role of the cripto (EGF-CFC) family in embryogenesis and cancer.
Growth factors (Chur, Switzerland) 2004;22(3):133-9.
2004: Antonella De Luca; Michele Grassii; Monica R Maiello; Massimo Di Maio; Mario Mancino; Ermelinda De Maio; Cesare Gridelli; Francesco Perrone; Nicola Normanno
Does the sequence of gemcitabine and vinorelbine affect their efficacy in non-small cell lung cancer in vitro?
Anticancer research 2004;24(5A):2985-9.
2004: Nicola Normanno; Massimo Di Maio; Francesco Perrone; Manuela Campiglio
Molecular markers to predict response to gefitinib: EGFR, ErbB-2, or more?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(10):2035-6; author reply 2036-7.
2004: Manuela Campiglio; Nicola Normanno; Sylvie Ménard
Re: Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors.
Journal of the National Cancer Institute 2004;96(9):715; author reply 715-6.
2004: Manuela Campiglio; Alberta Locatelli; CLELIA OLGIATI; Nicola Normanno; Giulia Somenzi; Lucia Viganò; Marzia Fumagalli; Sylvie Ménard; Luca Gianni
Inhibition of proliferation and induction of apoptosis in breast cancer cells by the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ZD1839 ('Iressa') is independent of EGFR expression level.
Journal of cellular physiology 2004;198(2):259-68.
2004: Nicola Normanno; Antonella De Luca; Caterina Bianco; Monica R Maiello; Maria Vincenza Carriero; Aasia Rehman; Christian Wechselberger; Claudio Arra; Luigi Strizzi; Michele Sanicola; David S Salomon
Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells.
Journal of cellular physiology 2004;198(1):31-9.
2003: Antonio Pinto; Rosaria De Filippi; Ferdinando Frigeri; Gaetano Corazzelli; Nicola Normanno
Aging and the hemopoietic system.
Critical reviews in oncology/hematology 2003;48(Suppl):S3-S12.
2003: Heather B Adkins; Caterina Bianco; Susan G Schiffer; Paul Rayhorn; Mohammad Zafari; Anne E Cheung; Olivia Orozco; Dian Olson; Antonella De Luca; Ling Ling Chen; Konrad Miatkowski; Christopher D Benjamin; Nicola Normanno; Kevin P Williams; Matthew Jarpe; Doreen J Lepage; David Salomon; Michele Sanicola
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.
The Journal of clinical investigation 2003;112(4):575-87.
2003: Caterina Bianco; Luigi Strizzi; Aasia Rehman; Nicola Normanno; Christian Wechselberger; Youping Sun; Nadia Khan; Morihisa Hirota; Heather B Adkins; Kevin Williams; Richard U Margolis; Michele Sanicola; David S Salomon
A Nodal- and ALK4-independent signaling pathway activated by Cripto-1 through Glypican-1 and c-Src.
Cancer research 2003;63(6):1192-7.
2003: Nicola Normanno; Caterina Bianco; A De Luca; Monica R Maiello; David S Salomon
Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment.
Endocrine-related cancer 2003;10(1):1-21.
2003: Nicola Normanno; Monica R Maiello; Antonella De Luca
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs): simple drugs with a complex mechanism of action?
Journal of cellular physiology 2003;194(1):13-9.
2002: Antonio D'Antonio; Simona Losito; Sandro Pignata; Michele Grassi; Francesco Perrone; Antonella De Luca; Rosa Tambaro; Caterina Bianco; William J Gullick; Gibbes R Johnson; Vincenzo Rosario Iaffaioli; David S Salomon; Nicola Normanno
Transforming growth factor alpha, amphiregulin and cripto-1 are frequently expressed in advanced human ovarian carcinomas.
International journal of oncology 2002;21(5):941-8.
2002: Caterina Bianco; Heather B Adkins; Christian Wechselberger; Masaharu Seno; Nicola Normanno; Antonella De Luca; Youping Sun; Nadia Khan; Nicholas Kenney; Andreas Ebert; Kevin P Williams; Michele Sanicola; David S Salomon
Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells.
Molecular and cellular biology 2002;22(8):2586-97.
2002: Nicola Normanno; Manuela Campiglio; Luca A De; Giulia Somenzi; Monica R Maiello; Fortunato Ciardiello; Luca Gianni; David S Salomon; S Menard
Cooperative inhibitory effect of ZD1839 (Iressa) in combination with trastuzumab (Herceptin) on human breast cancer cell growth.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13(1):65-72.
2002: Caterina Bianco; Nicola Normanno; Antonella De Luca; Monica R Maiello; Christian Wechselberger; Youping Sun; Nadia Khan; Heather B Adkins; Michele Sanicola; Barbara K Vonderhaar; Bruce Cohen; Masaharu Seno; David Salomon
Detection and localization of Cripto-1 binding in mouse mammary epithelial cells and in the mouse mammary gland using an immunoglobulin-cripto-1 fusion protein.
Journal of cellular physiology 2002;190(1):74-82.
2001: Nicola Normanno; C Bianco; Antonella De Luca; David S Salomon
The role of EGF-related peptides in tumor growth.
Frontiers in bioscience : a journal and virtual library 2001;6():D685-707.
2000: D S Saloman; Caterina Bianco; Andreas Ebert; Nadia I Khan; ML De Santis; Nicola Normanno; Christian Wechselberger; Masaharu Seno; K Williams; Michele Sanicola; S Foley; W J Gullick; G Persico
The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.
Endocrine-related cancer 2000;7(4):199-226.
2000: Antonella De Luca; Claudio Arra; Antonio D'Antonio; Amelia Casamassimi; Simona Losito; P Ferraro; Fortunato Ciardiello; David S Salomon; Nicola Normanno
Simultaneous blockage of different EGF-like growth factors results in efficient growth inhibition of human colon carcinoma xenografts.
Oncogene 2000;19(51):5863-71.
2000: Antonella De Luca; Sandro Pignata; Amelia Casamassimi; Antonio D'Antonio; C Gridelli; A Rossi; Franco Cremona; Valerio Parisi; Andrea de Matteis; Nicola Normanno
Detection of circulating tumor cells in carcinoma patients by a novel epidermal growth factor receptor reverse transcription-PCR assay.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1439-44.
2000: Amelia Casamassimi; A De Luca; S Agrawal; Kurt Stromberg; David S Salomon; Nicola Normanno
EGF-related antisense oligonucleotides inhibit the proliferation of human ovarian carcinoma cells.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(3):319-25.
1999: Nicola Normanno; Giampaolo Tortora; A De Luca; G Pomatico; Amelia Casamassimi; Sudhir Agrawal; J Mendelsohn; Angelo Raffaele Bianco; Fortunato Ciardiello
Synergistic growth inhibition and induction of apoptosis by a novel mixed backbone antisense oligonucleotide targeting CRIPTO in combination with C225 anti-EGFR monoclonal antibody and 8-Cl-cAMP in human GEO colon cancer cells.
Oncology reports 1999;6(5):1105-9.
1999: E De Angelis; M Grassi; W J Gullick; G R Johnson; Giovanni B Rossi; Alfonso Tempesta; F De Angelis; A De Luca; David S Salomon; Nicola Normanno
Expression of cripto and amphiregulin in colon mucosa from high risk colon cancer families.
International journal of oncology 1999;14(3):437-40.
1999: Antonella De Luca; Amelia Casamassimi; M P Selvam; Simona Losito; Fortunato Ciardiello; Sudhir Agrawal; David S Salomon; Nicola Normanno
EGF-related peptides are involved in the proliferation and survival of MDA-MB-468 human breast carcinoma cells.
International journal of cancer. Journal international du cancer 1999;80(4):589-94.
1998: Nicola Normanno; Antonella De Luca; A Castaldo; Amelia Casamassimi; Anna Di Popolo; Raffaele Zarrilli; Antonio Porcellini; Angela Maria Acquaviva; VE Avvedimento; Sandro Pignata
Apolipoprotein A-I reverse transcriptase-polymerase chain reaction analysis for detection of hematogenous colon cancer dissemination.
International journal of oncology 1998;13(3):443-7.
1998: Nicola Normanno; A De Luca; David S Salomon; F Ciardiello
Epidermal growth factor-related peptides as targets for experimental therapy of human colon carcinoma.
Cancer detection and prevention 1998;22(1):62-7.
1997: Antonella De Luca; M P Selvam; C Sandomenico; Stefano Pepe; Angelo Raffaele Bianco; Fortunato Ciardiello; David S Salomon; Nicola Normanno
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells.
International journal of cancer. Journal international du cancer 1997;73(2):277-82.
1997: Nicola Normanno; Fortunato Ciardiello
EGF-related peptides in the pathophysiology of the mammary gland.
Journal of mammary gland biology and neoplasia 1997;2(2):143-51.
1997: S Kannan; ML De Santis; M Lohmeyer; DJ Riese; Gilbert H Smith; N Hynes; Masaharu Seno; R Brandt; Caterina Bianco; G Persico; Nicholas Kenney; Nicola Normanno; I Martinez-Lacaci; F Ciardiello; David F Stern; W J Gullick; David S Salomon
Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells.
The Journal of biological chemistry 1997;272(6):3330-5.
1996: Gabriella Mincione; Caterina Bianco; S Kannan; Giulia Colletta; Fortunato Ciardiello; M Sliwkowski; Y Yarden; Nicola Normanno; A Pramaggiore; N Kim; David S Salomon
Enhanced expression of heregulin in c-erb B-2 and c-Ha-ras transformed mouse and human mammary epithelial cells.
Journal of cellular biochemistry 1996;60(4):437-46.
1996: Nicola Normanno; C Bianco; Vincenzo Damiano; E de Angelis; M P Selvam; M Grassi; G Magliulo; Giampaolo Tortora; Angelo Raffaele Bianco; J Mendelsohn; David S Salomon; Fortunato Ciardiello
Growth inhibition of human colon carcinoma cells by combinations of anti-epidermal growth factor-related growth factor antisense oligonucleotides.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(3):601-9.
1995: Nicola Normanno; M P Selvam; C Bianco; Vincenzo Damiano; E de Angelis; M Grassi; G Magliulo; Giampaolo Tortora; David S Salomon; Fortunato Ciardiello
Amphiregulin anti-sense oligodeoxynucleotides inhibit growth and transformation of a human colon carcinoma cell line.
International journal of cancer. Journal international du cancer 1995;62(6):762-6.
1995: Nicola Normanno; N Kim; D Wen; K Smith; A L Harris; Greg Plowman; Giulia Colletta; Fortunato Ciardiello; D S Salomon
Expression of messenger RNA for amphiregulin, heregulin, and cripto-1, three new members of the epidermal growth factor family, in human breast carcinomas.
Breast cancer research and treatment 1995;35(3):293-7.
1995: David S Salomon; R Brandt; Fortunato Ciardiello; Nicola Normanno
Epidermal growth factor-related peptides and their receptors in human malignancies.
Critical reviews in oncology/hematology 1995;19(3):183-232.
1995: David S Salomon; Nicola Normanno; Fortunato Ciardiello; R Brandt; M Shoyab; G J Todaro
The role of amphiregulin in breast cancer.
Breast cancer research and treatment 1995;33(2):103-14.
1994: R Brandt; Nicola Normanno; W J Gullick; J H Lin; R Harkins; D Schneider; B W Jones; Fortunato Ciardiello; M G Persico; F Armenante
Identification and biological characterization of an epidermal growth factor-related protein: cripto-1.
The Journal of biological chemistry 1994;269(25):17320-8.
1994: C F Qi; D S Liscia; Nicola Normanno; GR Merlo; G R Johnson; W J Gullick; Fortunato Ciardiello; T Saeki; R Brandt; N Kim
Expression of transforming growth factor alpha, amphiregulin and cripto-1 in human breast carcinomas.
British journal of cancer 1994;69(5):903-10.
1994: Nicola Normanno; M P Selvam; C F Qi; T Saeki; G Johnson; N Kim; Fortunato Ciardiello; M Shoyab; Greg Plowman; R Brandt
Amphiregulin as an autocrine growth factor for c-Ha-ras- and c-erbB-2-transformed human mammary epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2790-4.
1994: Fortunato Ciardiello; Giampaolo Tortora; C Bianco; M P Selvam; F Basolo; G Fontanini; F Pacifico; Nicola Normanno; R Brandt; M G Persico
Inhibition of CRIPTO expression and tumorigenicity in human colon cancer cells by antisense RNA and oligodeoxynucleotides.
Oncogene 1994;9(1):291-8.
1994: Nicola Normanno; Fortunato Ciardiello; R Brandt; David S Salomon
Epidermal growth factor-related peptides in the pathogenesis of human breast cancer.
Breast cancer research and treatment 1994;29(1):11-27.
1993: N J Kenney; T Saeki; M Gottardis; N Kim; P Garcia-Morales; Mary Beth Martin; Nicola Normanno; Fortunato Ciardiello; A Day; M L Cutler
Expression of transforming growth factor alpha antisense mRNA inhibits the estrogen-induced production of TGF alpha and estrogen-induced proliferation of estrogen-responsive human breast cancer cells.
Journal of cellular physiology 1993;156(3):497-514.
1993: Fortunato Ciardiello; C Bianco; Nicola Normanno; Gustavo Baldassarre; Stefano Pepe; Giampaolo Tortora; Angelo Raffaele Bianco; David S Salomon
Infection with a transforming growth factor alpha anti-sense retroviral expression vector reduces the in vitro growth and transformation of a human colon cancer cell line.
International journal of cancer. Journal international du cancer 1993;54(6):952-8.
1992: T Saeki; K Stromberg; C F Qi; W J Gullick; E Tahara; Nicola Normanno; Fortunato Ciardiello; N Kenney; G R Johnson; David S Salomon
Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors.
Cancer research 1992;52(12):3467-73.
1992: P Correale; antonio procopio; L Celio; Michele Caraglia; G Genua; V Coppola; Stefano Pepe; Nicola Normanno; I Vecchio; Giovannella Palmieri
Phorbol 12-myristate 13-acetate induces resistance of human melanoma cells to natural-killer- and lymphokine-activated-killer-mediated cytotoxicity.
Cancer immunology, immunotherapy : CII 1992;34(4):272-8.
1992: Fortunato Ciardiello; M Gottardis; F Basolo; Stefano Pepe; Nicola Normanno; Robert B Dickson; Angelo Raffaele Bianco; David S Salomon
Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-alpha genes on in vitro transformation of human mammary epithelial cells.
Molecular carcinogenesis 1992;6(1):43-52.
1991: T Saeki; A Cristiano; M J Lynch; M Brattain; N Kim; Nicola Normanno; N Kenney; Fortunato Ciardiello; David S Salomon
Regulation by estrogen through the 5'-flanking region of the transforming growth factor alpha gene.
Molecular endocrinology (Baltimore, Md.) 1991;5(12):1955-63.
1991: S Scala; R Pacelli; Rosario Vincenzo Iaffaioli; Nicola Normanno; Stefano Pepe; Giuseppe Frasci; G Genua; T Tsuruo; Pierosandro Tagliaferri; Angelo Raffaele Bianco
Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells.
Cancer research 1991;51(18):4898-902.
1991: Alfredo Budillon; Pierosandro Tagliaferri; Michele Caraglia; M R Torrisi; Nicola Normanno; S Iacobelli; G Palmieri; M P Stoppelli; Luigi Frati; Angelo Raffaele Bianco
Upregulation of epidermal growth factor receptor induced by alpha-interferon in human epidermoid cancer cells.
Cancer research 1991;51(4):1294-9.