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Reina Bendayan

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Olena Kis; Sharon L Walmsley; Jason Zastre; Md Tozammel Hoque; Reina Bendayan
Role of drug efflux and uptake transporters in atazanavir intestinal permeability and drug-drug interactions.
Shannon Dallas; Reina Bendayan; Michelle L Block; Marcelo G Bonini; Patrick Ronaldson; Deborah M Thompson; David S Miller
Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment.
Matthew R Durk; Eason Lee; David S Miller; Reina Bendayan; Christopher R Campos; Ronald E Cannon; Gary N Y Chan; Edwin Chiu Yuen Chow; John C Peart; K Sandy Pang
1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells.

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All Publications

2013: Olena Kis; Sharon L Walmsley; Jason Zastre; Md Tozammel Hoque; Reina Bendayan
Role of drug efflux and uptake transporters in atazanavir intestinal permeability and drug-drug interactions.
Pharmaceutical research 2013;30(4):1050-64.
2013: Shannon Dallas; Reina Bendayan; Michelle L Block; Marcelo G Bonini; Patrick Ronaldson; Deborah M Thompson; David S Miller
Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment.
Journal of neuroinflammation 2013;10(1):58.
2012: Matthew R Durk; Eason Lee; David S Miller; Reina Bendayan; Christopher R Campos; Ronald E Cannon; Gary N Y Chan; Edwin Chiu Yuen Chow; John C Peart; K Sandy Pang
1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells.
Journal of neurochemistry 2012;123(6):944-53.
2012: Nilasha Banerjee; Christine Allen; Reina Bendayan
Differential role of organic anion-transporting polypeptides in estrone-3-sulphate uptake by breast epithelial cells and breast cancer cells.
The Journal of pharmacology and experimental therapeutics 2012;342(2):510-9.
2012: Md Tozammel Hoque; Kevin R Robillard; Reina Bendayan
Regulation of breast cancer resistant protein by peroxisome proliferator-activated receptor α in human brain microvessel endothelial cells.
Molecular pharmacology 2012;81(4):598-609.
2012: Tamima Ashraf; Nilasha Banerjee; Olena Kis; Reina Bendayan
Drug transporters at brain barriers: expression and regulation by neurological disorders.
Advances in experimental medicine and biology 2012;763():20-69.
2012: Adrienne C Müller; Srinivas Patnala; Reina Bendayan; Olena Kis; Isadore Kanfer
Interactions between phytochemical components of Sutherlandia frutescens and the antiretroviral, atazanavir in vitro: implications for absorption and metabolism.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2012;15(2):221-33.
2011: Tamima Ashraf; Yuri Persidsky; Patrick Ronaldson; Reina Bendayan
Regulation of P-glycoprotein by human immunodeficiency virus-1 in primary cultures of human fetal astrocytes.
Journal of neuroscience research 2011;89(11):1773-82.
2011: Gary N Y Chan; Carolyn L Cummins; Md Tozammel Hoque; Reina Bendayan
Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells.
Journal of neurochemistry 2011;118(2):163-75.
2011: Michelle Di Risio; Peri J Ballantyne; Stanley E Read; Reina Bendayan
"HIV isn't me…": HIV+ adolescents' experiences in a positive context of support and treatment.
AIDS care 2011;23(6):694-9.
2011: Gary N Y Chan; Reina Bendayan
Molecular and functional characterization of P-glycoprotein in vitro.
Methods in molecular biology (Clifton, N.J.) 2011;686():313-36.
2010: Olena Kis; Jason A Zastre; Manisha Ramaswamy; Reina Bendayan
pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: potential role in antiretroviral drug oral bioavailability and drug-drug interactions.
The Journal of pharmacology and experimental therapeutics 2010;334(3):1009-22.
2010: Patrick Ronaldson; Tamima Ashraf; Reina Bendayan
Regulation of multidrug resistance protein 1 by tumor necrosis factor alpha in cultured glial cells: involvement of nuclear factor-kappaB and c-Jun N-terminal kinase signaling pathways.
Molecular pharmacology 2010;77(4):644-59.
2010: Olena Kis; Kevin Robillard; Gary N Y Chan; Reina Bendayan
The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters.
Trends in pharmacological sciences 2010;31(1):22-35.
2009: Qun Liu; Andrew M Rauth; Jiang Liu; Karlo Babakhanian; Xinyue Wang; Reina Bendayan; Xiao Yu Wu
Characterization of a microsphere formulation containing glucose oxidase and its in vivo efficacy in a murine solid tumor model.
Pharmaceutical research 2009;26(10):2343-57.
2009: Jason A Zastre; Gary N Y Chan; Patrick Ronaldson; Manisha Ramaswamy; Pierre O Couraud; Ignacio Romero; Babette Weksler; Moise Bendayan; Reina Bendayan
Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line.
Journal of neuroscience research 2009;87(4):1023-36.
2008: Patrick Ronaldson; Yuri Persidsky; Reina Bendayan
Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection.
Glia 2008;56(16):1711-35.
2008: Niladri Chattopadhyay; Jason Zastre; Ho Lun Wong; Xiao Yu Wu; Reina Bendayan
Solid lipid nanoparticles enhance the delivery of the HIV protease inhibitor, atazanavir, by a human brain endothelial cell line.
Pharmaceutical research 2008;25(10):2262-71.
2008: Patrick Ronaldson; Reina Bendayan
HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells.
Journal of neurochemistry 2008;106(3):1298-313.
2008: C Woodland; T T Huang; E Gryz; Reina Bendayan; J P Fawcett
Expression, activity and regulation of CYP3A in human and rodent brain.
Drug metabolism reviews 2008;40(1):149-68.
2007: Karlo Babakhanian; Moise Bendayan; Reina Bendayan
Localization of P-glycoprotein at the nuclear envelope of rat brain cells.
Biochemical and biophysical research communications 2007;361(2):301-6.
2007: Ho Lun Wong; Reina Bendayan; Andrew M Rauth; Yongqiang Li; Xiao Yu Wu
Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles.
Advanced drug delivery reviews 2007;59(6):491-504.
2007: Gloria Lee; Karlo Babakhanian; Manisha Ramaswamy; Alexandre Prat; Karolina Wosik; Reina Bendayan
Expression of the ATP-binding cassette membrane transporter, ABCG2, in human and rodent brain microvessel endothelial and glial cell culture systems.
Pharmaceutical research 2007;24(7):1262-74.
2007: Ho Lun Wong; Andrew M Rauth; Reina Bendayan; Xiao Yu Wu
In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;65(3):300-8.
2006: Ho Lun Wong; Reina Bendayan; Andrew M Rauth; Xiao Yu Wu
Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(3):275-84.
2006: Reina Bendayan; Patrick Ronaldson; Diane Gingras; Moise Bendayan
In situ localization of P-glycoprotein (ABCB1) in human and rat brain.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(10):1159-67.
2006: Patrick Ronaldson; Reina Bendayan
HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein.
Molecular pharmacology 2006;70(3):1087-98.
2006: Ho Lun Wong; Andrew M Rauth; Reina Bendayan; Janet L Manias; Manisha Ramaswamy; Zengshe Liu; Sevim Z Erhan; Xiao Yu Wu
A new polymer-lipid hybrid nanoparticle system increases cytotoxicity of doxorubicin against multidrug-resistant human breast cancer cells.
Pharmaceutical research 2006;23(7):1574-85.
2006: Shannon Dallas; David S Miller; Reina Bendayan
Multidrug resistance-associated proteins: expression and function in the central nervous system.
Pharmacological reviews 2006;58(2):140-61.
2006: Ho Lun Wong; Reina Bendayan; Andrew M Rauth; Hui Yi Xue; Karlo Babakhanian; Xiao Yu Wu
A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle system.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1372-81.
2006: Michelle D Furler; Thomas R Einarson; Sharon Walmsley; Margaret Millson; Reina Bendayan
Longitudinal trends in antiretroviral use in a cohort of men and women in Ontario, Canada.
AIDS patient care and STDs 2006;20(4):245-57.
2006: Richard Y Cheung; Andrew M Rauth; Patrick Ronaldson; Reina Bendayan; Xiao Yu Wu
In vitro toxicity to breast cancer cells of microsphere-delivered mitomycin C and its combination with doxorubicin.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2006;62(3):321-31.
2004: Michelle D Furler; Thomas R Einarson; Sharon Walmsley; Margaret Millson; Reina Bendayan
Polypharmacy in HIV: impact of data source and gender on reported drug utilization.
AIDS patient care and STDs 2004;18(10):568-86.
2004: Gloria Lee; Reina Bendayan
Functional expression and localization of P-glycoprotein in the central nervous system: relevance to the pathogenesis and treatment of neurological disorders.
Pharmaceutical research 2004;21(8):1313-30.
2004: Ho Lun Wong; Reina Bendayan; Andrew M Rauth; Xiao Yu Wu
Development of solid lipid nanoparticles containing ionically complexed chemotherapeutic drugs and chemosensitizers.
Journal of pharmaceutical sciences 2004;93(8):1993-2008.
2004: Shannon Dallas; Lyanne Schlichter; Reina Bendayan
Multidrug resistance protein (MRP) 4- and MRP 5-mediated efflux of 9-(2-phosphonylmethoxyethyl)adenine by microglia.
The Journal of pharmacology and experimental therapeutics 2004;309(3):1221-9.
2004: Shannon Dallas; Patrick Ronaldson; Moise Bendayan; Reina Bendayan
Multidrug resistance protein 1-mediated transport of saquinavir by microglia.
Neuroreport 2004;15(7):1183-6.
2004: Patrick Ronaldson; Gloria Lee; Shannon Dallas; Reina Bendayan
Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines.
Pharmaceutical research 2004;21(5):811-8.
2004: Patrick Ronaldson; Moise Bendayan; Diane Gingras; Micheline Piquette-Miller; Reina Bendayan
Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures.
Journal of neurochemistry 2004;89(3):788-800.
2004: Michelle D Furler; Thomas R Einarson; Margaret Millson; Sharon Walmsley; Reina Bendayan
Medicinal and recreational marijuana use by patients infected with HIV.
AIDS patient care and STDs 2004;18(4):215-28.
2003: Shannon Dallas; Xiaoping Zhu; Sylvain Baruchel; Lyanne Schlichter; Reina Bendayan
Functional expression of the multidrug resistance protein 1 in microglia.
The Journal of pharmacology and experimental therapeutics 2003;307(1):282-90.
2003: Zhi Liu; James R Ballinger; Andrew M Rauth; Reina Bendayan; Xiao Yu Wu
Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres.
The Journal of pharmacy and pharmacology 2003;55(8):1063-73.
2003: Michelle D Furler; Thomas R Einarson; Sharon Walmsley; Margaret Millson; Reina Bendayan
Use of complementary and alternative medicine by HIV-infected outpatients in Ontario, Canada.
AIDS patient care and STDs 2003;17(4):155-68.
2002: Reina Bendayan; Gloria Lee; Moise Bendayan
Functional expression and localization of P-glycoprotein at the blood brain barrier.
Microscopy research and technique 2002;57(5):365-80.
2001: Zhi Liu; R Cheung; Xiao Yu Wu; James R Ballinger; Reina Bendayan; Andrew M Rauth
A study of doxorubicin loading onto and release from sulfopropyl dextran ion-exchange microspheres.
Journal of controlled release : official journal of the Controlled Release Society 2001;77(3):213-24.
2001: Gloria Lee; Shannon Dallas; M Hong; Reina Bendayan
Drug transporters in the central nervous system: brain barriers and brain parenchyma considerations.
Pharmacological reviews 2001;53(4):569-96.
2001: Diana Stempak; Shannon Dallas; Julia Klein; Reina Bendayan; Gideon Koren; Sylvain Baruchel
Glutathione stability in whole blood: effects of various deproteinizing acids.
Therapeutic drug monitoring 2001;23(5):542-9.
2001: G Lee; Lyanne Schlichter; M Bendayan; Reina Bendayan
Functional expression of P-glycoprotein in rat brain microglia.
The Journal of pharmacology and experimental therapeutics 2001;299(1):204-12.
2001: Zhi Liu; Reina Bendayan; Xiao Yu Wu
Triton-X-100-modified polymer and microspheres for reversal of multidrug resistance.
The Journal of pharmacy and pharmacology 2001;53(6):779-87.
2001: S Leung; Reina Bendayan
Uptake properties of lamivudine (3TC) by a continuous renal epithelial cell line.
Canadian journal of physiology and pharmacology 2001;79(1):59-66.
2001: M Hong; Lyanne Schlichter; Reina Bendayan
A novel zidovudine uptake system in microglia.
The Journal of pharmacology and experimental therapeutics 2001;296(1):141-9.
2000: Shannon Dallas; S E Read; S King; Gideon Koren; Reina Bendayan
Pharmacokinetic interaction between zidovudine and trimethoprim/sulphamethoxazole in HIV-1 infected children.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 2000;11(5):254-8.
2000: Zhi Liu; Xiao Yu Wu; James R Ballinger; Reina Bendayan
Synthesis and characterization of surface-hydrophobic ion-exchange microspheres and the effect of coating on drug release rate.
Journal of pharmaceutical sciences 2000;89(6):807-17.
2000: M Hong; Lyanne Schlichter; Reina Bendayan
A Na(+)-dependent nucleoside transporter in microglia.
The Journal of pharmacology and experimental therapeutics 2000;292(1):366-74.
1999: S Leung; Reina Bendayan
Role of P-glycoprotein in the renal transport of dideoxynucleoside analog drugs.
Canadian journal of physiology and pharmacology 1999;77(8):625-30.
1999: Zhi Liu; Xiao Yu Wu; Reina Bendayan
In vitro investigation of ionic polysaccharide microspheres for simultaneous delivery of chemosensitizer and antineoplastic agent to multidrug-resistant cells.
Journal of pharmaceutical sciences 1999;88(4):412-8.
1998: E C Lui; Reina Bendayan
Gentamicin uptake by LLCPK1 cells: effect of intracellular and extracellular pH changes.
Canadian journal of physiology and pharmacology 1998;76(2):155-60.
1997: S Robertson-Dallas; S E Read; Reina Bendayan
New drug interactions with zidovudine.
Pharmacotherapy 1997;17(6):1198-209.
1997: Reina Bendayan
Interaction of dipyridamole, a nucleoside transport inhibitor, with the renal transport of organic cations by LLCPK1 cells.
Canadian journal of physiology and pharmacology 1997;75(1):52-6.
1996: Reina Bendayan
Renal drug transport: a review.
Pharmacotherapy 1996;16(6):971-85.
1995: Reina Bendayan; W Georgis; S Rafi-Tari
Interaction of 3'-azido-3'-deoxythymidine with the organic base transporter in a cultured renal epithelium.
Pharmacotherapy 1995;15(3):338-44.
1994: Reina Bendayan; B Lo; Mel Silverman
Characterization of cimetidine transport in LLCPK1 cells.
Journal of the American Society of Nephrology : JASN 1994;5(1):75-84.
1993: Reina Bendayan; G Kennedy; R C Frecker; Edward M Sellers
Lack of effect of cimetidine on cigarette smoking.
European journal of clinical pharmacology 1993;44(1):51-5.
1990: Reina Bendayan; Edward M Sellers; Mel Silverman
Inhibition kinetics of cationic drugs on N'-methylnicotinamide uptake by brush border membrane vesicles from the dog kidney cortex.
Canadian journal of physiology and pharmacology 1990;68(4):467-75.
1990: Reina Bendayan; John Sullivan; C Shaw; R C Frecker; Edward M Sellers
Effect of cimetidine and ranitidine on the hepatic and renal elimination of nicotine in humans.
European journal of clinical pharmacology 1990;38(2):165-9.