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Anna Norrby-Teglund

Research Profile

Living Beings

Streptococcus pyogenes

Disorders

Chemicals & Drugs

Physiology

Lymphocyte Activation

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Neutralization Tests

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Publications

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Sushma Prabhakara; Aswin Sai Narain Seshasayee; Srikanth Mairpady Shambat; Rajalakshmi Srinivasan; Atanu Basu; Supriya Khedkar; Anna Norrby-Teglund; Gayathri Arakere
Genome sequencing unveils a novel sea enterotoxin-carrying PVL phage in Staphylococcus aureus ST772 from India.
Linda Johansson; Anna Norrby-Teglund
Immunopathogenesis of streptococcal deep tissue infections.
Axana Haggar; John Melbin Jose Joshua; Rajesh Kumar; Narinder Mehra; Andreas Nerlich; Vinod J Abraham; Rene Bergmann; Kootallur N Brahmadathan; Gursharan S Chhatwal; Vanita Dhanda; Pallab Ray; Anna Norrby-Teglund
Clinical and microbiologic characteristics of invasive Streptococcus pyogenes infections in north and south India.

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All Publications

2013: Sushma Prabhakara; Aswin Sai Narain Seshasayee; Srikanth Mairpady Shambat; Rajalakshmi Srinivasan; Atanu Basu; Supriya Khedkar; Anna Norrby-Teglund; Gayathri Arakere
Genome sequencing unveils a novel sea enterotoxin-carrying PVL phage in Staphylococcus aureus ST772 from India.
PloS one 2013;8(3):e60013.
2013: Linda Johansson; Anna Norrby-Teglund
Immunopathogenesis of streptococcal deep tissue infections.
Current topics in microbiology and immunology 2013;368():173-88.
2012: Axana Haggar; John Melbin Jose Joshua; Rajesh Kumar; Narinder Mehra; Andreas Nerlich; Vinod J Abraham; Rene Bergmann; Kootallur N Brahmadathan; Gursharan S Chhatwal; Vanita Dhanda; Pallab Ray; Anna Norrby-Teglund
Clinical and microbiologic characteristics of invasive Streptococcus pyogenes infections in north and south India.
Journal of clinical microbiology 2012;50(5):1626-31.
2012: Erika Hertzén; Marton Janos; Linda Johansson; Rita Kansal; Malak Kotb; Victor Nizet; Samira Dahesh; Alexander Hecht; Anna Norrby-Teglund
Intracellular Streptococcus pyogenes in human macrophages display an altered gene expression profile.
PloS one 2012;7(4):e35218.
2011: Torsten G Loof; Matthias Mörgelin; Anna Norrby-Teglund; Sonja Oehmcke; Anders I Olin; Ulrich Theopold; Gerhard Dickneite; Linda Johansson; Heiko Herwald
Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense.
Blood 2011;118(9):2589-98.
2011: Jonas Lannergård; Anna Norrby-Teglund; Margaretha Stålhammar-Carlemalm; Johan Waldemarsson; Mattias C U Gustafsson; Mattias Gustafsson
The Hypervariable region of Streptococcus pyogenes M protein escapes antibody attack by antigenic variation and weak immunogenicity.
Cell host & microbe 2011;10(2):147-57.
2010: Anna Granath; Anna Norrby-Teglund; Rolf Uddman; Lars-Olaf Cardell
Reduced iNOS expression in adenoids from children with otitis media with effusion.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2010;21(8):1151-6.
2010: Oliver Goldmann; Erika Hertzén; Alexander Hecht; Heike Schmidt; Sabine Lehne; Anna Norrby-Teglund; Eva Medina
Inducible cyclooxygenase released prostaglandin E2 modulates the severity of infection caused by Streptococcus pyogenes.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(4):2372-81.
2010: A Haggar; J-I Flock; Anna Norrby-Teglund
Extracellular adherence protein (Eap) from Staphylococcus aureus does not function as a superantigen.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2010;16(8):1155-8.
2010: Linda Johansson; Pontus Thulin; Donald E Low; Anna Norrby-Teglund
Getting under the skin: the immunopathogenesis of Streptococcus pyogenes deep tissue infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010;51(1):58-65.
2010: Adam Linder; Linda Johansson; Pontus Thulin; Erika Hertzén; Matthias Mörgelin; Bertil Christensson; Lars Björck; Anna Norrby-Teglund; Per Akesson
Erysipelas caused by group A streptococcus activates the contact system and induces the release of heparin-binding protein.
The Journal of investigative dermatology 2010;130(5):1365-72.
2010: Erika Hertzén; Linda Johansson; Robert Wallin; Heike Schmidt; Mirko Kroll; Anders P Rehn; Ramy Aziz; Matthias Mörgelin; Anna Norrby-Teglund
M1 protein-dependent intracellular trafficking promotes persistence and replication of Streptococcus pyogenes in macrophages.
Journal of innate immunity 2010;2(6):534-45.
2009: Erik Malmström; Matthias Mörgelin; Martin Malmsten; Linda Johansson; Anna Norrby-Teglund; Oonagh Shannon; Artur Schmidtchen; Joost C M Meijers; Heiko Herwald
Protein C inhibitor--a novel antimicrobial agent.
PLoS pathogens 2009;5(12):e1000698.
2009: Linda Johansson; Anna Linnér; Jonas Sundén-Cullberg; Axana Haggar; Heiko Herwald; Karin Loré; Carl Johan Treutiger; Anna Norrby-Teglund
Neutrophil-derived hyperresistinemia in severe acute streptococcal infections.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(6):4047-54.
2009: Parham Sendi; Linda Johansson; Samira Dahesh; Nina M Van-Sorge; Jessica Darenberg; Mari Norgren; Jan Sjölin; Victor Nizet; Anna Norrby-Teglund
Bacterial phenotype variants in group B streptococcal toxic shock syndrome.
Emerging infectious diseases 2009;15(2):223-32.
2009: Anna Vikerfors; Axana Haggar; Jessica Darenberg; Aili Low; Asa Melhus; Johan Hedlund; Staffan Sylvan; Anna Norrby-Teglund; Britt-Marie Eriksson
Severe group A streptococcal infections in Uppsala County, Sweden: clinical and molecular characterization of a case cluster from 2006 to 2007.
Scandinavian journal of infectious diseases 2009;41(11-12):823-30.
2008: Lena Lövkvist; Hong Sjölinder; Rahma Wehelie; HELENA ARO; Anna Norrby-Teglund; Laura Plant; Ann-Beth Jonsson
CD46 Contributes to the severity of group A streptococcal infection.
Infection and immunity 2008;76(9):3951-8.
2008: Linda Johansson; Pontus Thulin; Parham Sendi; Erika Hertzén; Adam Linder; Per Akesson; Donald E Low; Birgitta Agerberth; Anna Norrby-Teglund
Cathelicidin LL-37 in severe Streptococcus pyogenes soft tissue infections in humans.
Infection and immunity 2008;76(8):3399-404.
2008: Maren von Köckritz-Blickwede; Oliver Goldmann; Pontus Thulin; Katja Heinemann; Anna Norrby-Teglund; Manfred Rohde; Eva Medina
Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation.
Blood 2008;111(6):3070-80.
2008: P Sendi; L Johansson; Anna Norrby-Teglund
Invasive group B Streptococcal disease in non-pregnant adults : a review with emphasis on skin and soft-tissue infections.
Infection 2008;36(2):100-11.
2008: Lisa I Påhlman; Anders I Olin; Jessica Darenberg; Matthias Mörgelin; Malak Kotb; Heiko Herwald; Anna Norrby-Teglund
Soluble M1 protein of Streptococcus pyogenes triggers potent T cell activation.
Cellular microbiology 2008;10(2):404-14.
2008: Fredrik Kahn; Matthias Mörgelin; Oonagh Shannon; Anna Norrby-Teglund; Heiko Herwald; Anders I Olin; Lars Björck
Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response.
PLoS pathogens 2008;4(9):e1000149.
2007: Oonagh Shannon; Erika Hertzén; Anna Norrby-Teglund; Matthias Mörgelin; Ulf Sjöbring; Lars Björck
Severe streptococcal infection is associated with M protein-induced platelet activation and thrombus formation.
Molecular microbiology 2007;65(5):1147-57.
2007: Jessica Darenberg; Bogdan Luca-Harari; Aftab Jasir; Andreas Sandgren; Helena Pettersson; Claes Schalén; Mari Norgren; Victoria Romanus; Anna Norrby-Teglund; Birgitta Henriques Normark
Molecular and clinical characteristics of invasive group A streptococcal infection in Sweden.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;45(4):450-8.
2007: Jonas Sundén-Cullberg; Thomas Nyström; Martin L Lee; Gail E Mullins; Leif Tokics; Jan Andersson; Anna Norrby-Teglund; Carl Johan Treutiger
Pronounced elevation of resistin correlates with severity of disease in severe sepsis and septic shock.
Critical care medicine 2007;35(6):1536-42.
2007: Pedram Sendi; Peter Graber; Linda Johansson; Anna Norrby-Teglund; Werner Zimmerli
Streptococcus agalactiae in relapsing cellulitis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;44(8):1141-2.
2006: Anna Norrby-Teglund; K N Haque; L Hammarström
Intravenous polyclonal IgM-enriched immunoglobulin therapy in sepsis: a review of clinical efficacy in relation to microbiological aetiology and severity of sepsis.
Journal of internal medicine 2006;260(6):509-16.
2006: Sara H Bengtson; Stephen B Phagoo; Anna Norrby-Teglund; Lisa Påhlman; Matthias Mörgelin; Bruce L Zuraw; L M Fredrik Leeb-Lundberg; Heiko Herwald
Kinin receptor expression during Staphylococcus aureus infection.
Blood 2006;108(6):2055-63.
2006: Lisa I Påhlman; Matthias Mörgelin; Jana Eckert; Linda Johansson; Wayne Russell; Kristian Riesbeck; Oliver Soehnlein; Lennart Lindbom; Anna Norrby-Teglund; Ralf R Schumann; Lars Björck; Heiko Herwald
Streptococcal M protein: a multipotent and powerful inducer of inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1221-8.
2006: Jonas Sunden-Cullberg; Anna Norrby-Teglund; Carl Johan Treutiger
The role of high mobility group box-1 protein in severe sepsis.
Current opinion in infectious diseases 2006;19(3):231-6.
2006: Pontus Thulin; Linda Johansson; Donald E Low; Bing Siang Gan; Malak Kotb; Allison McGeer; Anna Norrby-Teglund
Viable group A streptococci in macrophages during acute soft tissue infection.
PLoS medicine 2006;3(3):e53.
2006: Gunilla Goscinski; Eva Tano; Pontus Thulin; Anna Norrby-Teglund; Jan Sjölin
Release of SpeA from Streptococcus pyogenes after exposure to penicillin: dependency on dose and inhibition by clindamycin.
Scandinavian journal of infectious diseases 2006;38(11-12):983-7.
2005: Axana Haggar; Oonagh Shannon; Anna Norrby-Teglund; Jan-Ingmar Flock
Dual effects of extracellular adherence protein from Staphylococcus aureus on peripheral blood mononuclear cells.
The Journal of infectious diseases 2005;192(2):210-7.
2005: Kim Ekelund; Jessica Darenberg; Anna Norrby-Teglund; Steen Hoffmann; Didi Bang; Peter Skinhøj; Helle Bossen Konradsen
Variations in emm type among group A streptococcal isolates causing invasive or noninvasive infections in a nationwide study.
Journal of clinical microbiology 2005;43(7):3101-9.
2005: Jonas Sundén-Cullberg; Anna Norrby-Teglund; Ari Rouhiainen; Heikki Rauvala; Gunilla Herman; Kevin Tracey; Martin L Lee; Jan Andersson; Leif Tokics; Carl Johan Treutiger
Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock.
Critical care medicine 2005;33(3):564-73.
2005: Anna Norrby-Teglund; Matthew P Muller; Allison McGeer; Bing Siang Gan; Veena Guru; John Bohnen; Pontus Thulin; Donald E Low
Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous polyspecific immunoglobulin together with a conservative surgical approach.
Scandinavian journal of infectious diseases 2005;37(3):166-72.
2004: Birgitta Henriques Normark; Staffan Normark; Anna Norrby-Teglund
Staphylococcal protein A inflames the lungs.
Nature medicine 2004;10(8):780-1.
2004: Jessica Darenberg; Bo Söderquist; Birgitta Henriques Normark; Anna Norrby-Teglund
Differences in potency of intravenous polyspecific immunoglobulin G against streptococcal and staphylococcal superantigens: implications for therapy of toxic shock syndrome.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;38(6):836-42.
2004: Anders Enocksson; Jon Lundberg; Eddie Weitzberg; Anna Norrby-Teglund; Bo Svenungsson
Rectal nitric oxide gas and stool cytokine levels during the course of infectious gastroenteritis.
Clinical and diagnostic laboratory immunology 2004;11(2):250-4.
2004: Heiko Herwald; Henning Cramer; Matthias Mörgelin; Wayne Russell; Ulla Sollenberg; Anna Norrby-Teglund; Hans Flodgaard; Lennart Lindbom; Lars Björck
M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage.
Cell 2004;116(3):367-79.
2004: Nahla Ihendyane; E Sparrelid; B Wretlind; M Remberger; Jan Andersson; P Ljungman; Olle Ringdén; Birgitta Henriques Normark; U Allen; Donald E Low; Anna Norrby-Teglund
Viridans streptococcal septicaemia in neutropenic patients: role of proinflammatory cytokines.
Bone marrow transplantation 2004;33(1):79-85.
2003: Jessica Darenberg; Nahla Ihendyane; Jan Sjölin; Ewa Aufwerber; Sven Haidl; Per Follin; Jan Andersson; Anna Norrby-Teglund
Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome: a European randomized, double-blind, placebo-controlled trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;37(3):333-40.
2003: Axana Haggar; muzaffar hussain; Helena Lönnies; Mathias Herrmann; Anna Norrby-Teglund; Jan-Ingmar Flock
Extracellular adherence protein from Staphylococcus aureus enhances internalization into eukaryotic cells.
Infection and immunity 2003;71(5):2310-7.
2003: Anna Norrby-Teglund; Nahla Ihendyane; Jessica Darenberg
Intravenous immunoglobulin adjunctive therapy in sepsis, with special emphasis on severe invasive group A streptococcal infections.
Scandinavian journal of infectious diseases 2003;35(9):683-9.
2003: Malak Kotb; Anna Norrby-Teglund; Allison McGeer; Karen Green; Donald E Low
Association of human leukocyte antigen with outcomes of infectious diseases: the streptococcal experience.
Scandinavian journal of infectious diseases 2003;35(9):665-9.
2002: Malak Kotb; Anna Norrby-Teglund; Allison McGeer; Hesham El-Sherbini; M Tevfik Dorak; Ayesha Khurshid; Karen Green; Jeanie Peeples; Judy Wade; Glenys Thomson; Benjamin Schwartz; Donald E Low
An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections.
Nature medicine 2002;8(12):1398-404.
2002: Anna Norrby-Teglund; Gerald Nepom; Malak Kotb
Differential presentation of group A streptococcal superantigens by HLA class II DQ and DR alleles.
European journal of immunology 2002;32(9):2570-7.
2001: Anna Norrby-Teglund; Pontus Thulin; Bing Siang Gan; Malak Kotb; Allison McGeer; Jan Andersson; Donald E Low
Evidence for superantigen involvement in severe group a streptococcal tissue infections.
The Journal of infectious diseases 2001;184(7):853-60.
2001: S U Kazmi; Rita G Kansal; Ramy Aziz; M Hooshdaran; Anna Norrby-Teglund; Donald E Low; A B Halim; Malak Kotb
Reciprocal, temporal expression of SpeA and SpeB by invasive M1T1 group a streptococcal isolates in vivo.
Infection and immunity 2001;69(8):4988-95.
2001: Anna Norrby-Teglund; J E Berdal
Culture-negative severe septic shock: indications for streptococcal aetiology based on plasma antibodies and superantigenic activity.
Scandinavian journal of infectious diseases 2001;33(8):634-7.
2000: Anna Norrby-Teglund; S Chatellier; Donald E Low; Allison McGeer; Karen Green; Malak Kotb
Host variation in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection.
European journal of immunology 2000;30(11):3247-55.
2000: Anna Norrby-Teglund; Nahla Ihendyane; Rita G Kansal; H Basma; Malak Kotb; Jan Andersson; L Hammarström
Relative neutralizing activity in polyspecific IgM, IgA, and IgG preparations against group A streptococcal superantigens.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;31(5):1175-82.
2000: Rita G Kansal; Allison McGeer; Donald E Low; Anna Norrby-Teglund; Malak Kotb
Inverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection cases.
Infection and immunity 2000;68(11):6362-9.
2000: S Chatellier; Nahla Ihendyane; Rita G Kansal; F Khambaty; H Basma; Anna Norrby-Teglund; Donald E Low; Allison McGeer; Malak Kotb
Genetic relatedness and superantigen expression in group A streptococcus serotype M1 isolates from patients with severe and nonsevere invasive diseases.
Infection and immunity 2000;68(6):3523-34.
1999: H Basma; Anna Norrby-Teglund; Y Guedez; Allison McGeer; Donald E Low; O El-Ahmedy; Benjamin Schwartz; Malak Kotb
Risk factors in the pathogenesis of invasive group A streptococcal infections: role of protective humoral immunity.
Infection and immunity 1999;67(4):1871-7.
1998: H Basma; Anna Norrby-Teglund; Allison McGeer; Donald E Low; O El-Ahmedy; J B Dale; Benjamin Schwartz; Malak Kotb
Opsonic antibodies to the surface M protein of group A streptococci in pooled normal immunoglobulins (IVIG): potential impact on the clinical efficacy of IVIG therapy for severe invasive group A streptococcal infections.
Infection and immunity 1998;66(5):2279-83.
1998: Anna Norrby-Teglund; H Basma; Jan Andersson; Allison McGeer; Donald E Low; Malak Kotb
Varying titers of neutralizing antibodies to streptococcal superantigens in different preparations of normal polyspecific immunoglobulin G: implications for therapeutic efficacy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1998;26(3):631-8.
1997: Anna Norrby-Teglund; R Lustig; Malak Kotb
Differential induction of Th1 versus Th2 cytokines by group A streptococcal toxic shock syndrome isolates.
Infection and immunity 1997;65(12):5209-15.
1997: Anna Norrby-Teglund; Donald E Low; Allison McGeer; Malak Kotb
Superantigenic activity produced by group A streptococcal isolates is neutralized by plasma from IVIG-treated streptococcal toxic shock syndrome patients.
Advances in experimental medicine and biology 1997;418():563-6.
1997: Duane W Newton; Anna Norrby-Teglund; Allison McGeer; Donald E Low; P M Schlievert; Malak Kotb
Novel superantigens from streptococcal toxic shock syndrome Streptococcus pyogenes isolates.
Advances in experimental medicine and biology 1997;418():525-9.
1996: Anna Norrby-Teglund; R Kaul; Donald E Low; Allison McGeer; J Andersson; U Andersson; Malak Kotb
Evidence for the presence of streptococcal-superantigen-neutralizing antibodies in normal polyspecific immunoglobulin G.
Infection and immunity 1996;64(12):5395-8.
1996: Anna Norrby-Teglund; R Kaul; Donald E Low; Allison McGeer; Duane W Newton; J Andersson; U Andersson; Malak Kotb
Plasma from patients with severe invasive group A streptococcal infections treated with normal polyspecific IgG inhibits streptococcal superantigen-induced T cell proliferation and cytokine production.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):3057-64.
1995: Anna Norrby-Teglund; K Pauksens; Mari Norgren; Stig E Holm
Correlation between serum TNF alpha and IL6 levels and severity of group A streptococcal infections.
Scandinavian journal of infectious diseases 1995;27(2):125-30.
1994: Anna Norrby-Teglund; Duane W Newton; Malak Kotb; Stig E Holm; Mari Norgren
Superantigenic properties of the group A streptococcal exotoxin SpeF (MF).
Infection and immunity 1994;62(12):5227-33.
1994: Anna Norrby-Teglund; K Pauksens; Stig E Holm; Mari Norgren
Relation between low capacity of human sera to inhibit streptococcal mitogens and serious manifestation of disease.
The Journal of infectious diseases 1994;170(3):585-91.
1994: Anna Norrby-Teglund; Mari Norgren; Stig E Holm; U Andersson; J Andersson
Similar cytokine induction profiles of a novel streptococcal exotoxin, MF, and pyrogenic exotoxins A and B.
Infection and immunity 1994;62(9):3731-8.
1994: Anna Norrby-Teglund; Stig E Holm; Mari Norgren
Detection and nucleotide sequence analysis of the speC gene in Swedish clinical group A streptococcal isolates.
Journal of clinical microbiology 1994;32(3):705-9.