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Raymond Norton

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Genes & Molecular Sequences

Amino Acid Sequence

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Biomolecular Nuclear Magnetic Resonance

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Co-Publications
Name
22
Yao, Shenggen
16
Pennington, Michael
16
Pallaghy, Paul
12
Barnham, Kevin
11
Hinds, Mark
11
Olivera, Baldomero
10
Keizer, David
9
babon, jeffrey
9
Bach, Leon
9
Nicola, Nicos
9
Anders, Robin
9
Bulaj, Grzegorz
8
Yoshikami, Doju
6
Zhang, Jian-Guo
6
Headey, Stephen

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Publications

TOP 3
Drechsler Alison; Miles Andrew J; Norton Raymond S; Wallace B A; Separovic Frances
Effect of lipid on the conformation of the N-terminal region of equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study.
Norton Raymond S
Structures of sea anemone toxins.
Kuang Zhihe; Yao Shenggen; McNeil Kerrie A; Forbes Briony E; Wallace John C; Norton Raymond S
Insulin-like growth factor-I (IGF-I): solution properties and NMR chemical shift assignments near physiological pH.

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All Publications

2009: Drechsler Alison; Miles Andrew J; Norton Raymond S; Wallace B A; Separovic Frances
Effect of lipid on the conformation of the N-terminal region of equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study.
European biophysics journal : EBJ 2009;39(1):121-7.
2009: Norton Raymond S
Structures of sea anemone toxins.
Toxicon : official journal of the International Society on Toxinology 2009;54(8):1075-88.
2009: Kuang Zhihe; Yao Shenggen; McNeil Kerrie A; Forbes Briony E; Wallace John C; Norton Raymond S
Insulin-like growth factor-I (IGF-I): solution properties and NMR chemical shift assignments near physiological pH.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2009;19(3):226-31.
2009: Harris Karen S; Casey Joanne L; Coley Andrew M; Karas John A; Sabo Jennifer K; Tan Yen Yee; Dolezal Olan; Norton Raymond S; Hughes Andrew B; Scanlon Denis; Foley Michael
Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning.
The Journal of biological chemistry 2009;284(14):9361-71.
2009: Babon Jeffrey J; Sabo Jennifer K; Zhang Jian-Guo; Nicola Nicos A; Norton Raymond S
The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression.
Journal of molecular biology 2009;387(1):162-74.
2009: Khoo Keith K; Feng Zhi-Ping; Smith Brian J; Zhang Min-Min; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion.
Biochemistry 2009;48(6):1210-9.
2009: Kuang Zhihe; Yao Shenggen; Xu Yibin; Lewis Rowena S; Low Andrew; Masters Seth L; Willson Tracy A; Kolesnik Tatiana B; Nicholson Sandra E; Garrett Thomas J P; Norton Raymond S
SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
Journal of molecular biology 2009;386(3):662-74.
2009: MacRaild Christopher A; Illesinghe Jayamini; van Lierop Bianca J; Townsend Amanda L; Chebib Mary; Livett Bruce G; Robinson Andrea J; Norton Raymond S
Structure and activity of (2,8)-dicarba-(3,12)-cystino alpha-ImI, an alpha-conotoxin containing a nonreducible cystine analogue.
Journal of medicinal chemistry 2009;52(3):755-62.
2009: Fry Bryan G; Roelants Kim; Champagne Donald E; Scheib Holger; Tyndall Joel D A; King Glenn F; Nevalainen Timo J; Norman Janette A; Lewis Richard J; Norton Raymond S; Renjifo Camila; de la Vega Ricardo C Rodríguez
The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms.
Annual review of genomics and human genetics 2009;10():483-511.
2009: Han Pengfei; Zhang Xiuzhen; Norton Raymond S; Feng Zhi-Ping
Large-scale prediction of long disordered regions in proteins using random forests.
BMC bioinformatics 2009;10():8.
2008: Baldwin Graham S; Bailey Michael F; Shehan B Philip; Sims Ioulia; Norton Raymond S
Tyrosine modification enhances metal-ion binding.
The Biochemical journal 2008;416(1):77-84.
2008: Yao Shenggen; Zhang Min-Min; Yoshikami Doju; Azam Layla; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA.
Biochemistry 2008;47(41):10940-9.
2008: Babon Jeffrey J; Sabo Jennifer K; Soetopo Alfreda; Yao Shenggen; Bailey Michael F; Zhang Jian-Guo; Nicola Nicos A; Norton Raymond S
The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase.
Journal of molecular biology 2008;381(4):928-40.
2008: Yao Shenggen; Babon Jeffrey J; Norton Raymond S
Protein effective rotational correlation times from translational self-diffusion coefficients measured by PFG-NMR.
Biophysical chemistry 2008;136(2-3):145-51.
2008: Fiedler Brian; Zhang Min-Min; Buczek Oga; Azam Layla; Bulaj Grzegorz; Norton Raymond S; Olivera Baldomero M; Yoshikami Doju
Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7.
Biochemical pharmacology 2008;75(12):2334-44.
2008: Zhang Xuecheng; Perugini Matthew A; Yao Shenggen; Adda Christopher G; Murphy Vincent J; Low Andrew; Anders Robin F; Norton Raymond S
Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2.
Journal of molecular biology 2008;379(1):105-21.
2008: Ellison Michael; Feng Zhi-Ping; Park Anthony J; Zhang Xuecheng; Olivera Baldomero M; McIntosh J Michael; Norton Raymond S
Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.
Journal of molecular biology 2008;377(4):1216-27.
2008: Beeton Christine; Smith Brian J; Sabo Jennifer K; Crossley George; Nugent Daniel; Khaytin Ilya; Chi Victor; Chandy K George; Pennington Michael W; Norton Raymond S
The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferation.
The Journal of biological chemistry 2008;283(2):988-97.
2008: Norton Raymond S; McDonough Stefan I
Peptides targeting voltage-gated calcium channels.
Current pharmaceutical design 2008;14(24):2480-91.
2007: Kuang Zhihe; Yao Shenggen; McNeil Kerrie A; Thompson Julian A; Bach Leon A; Forbes Briony E; Wallace John C; Norton Raymond S
Cooperativity of the N- and C-terminal domains of insulin-like growth factor (IGF) binding protein 2 in IGF binding.
Biochemistry 2007;46(48):13720-32.
2007: Yang Xiaodong; Adda Christopher G; Keizer David W; Murphy Vince J; Rizkalla Michael M; Perugini Matthew A; Jackson David C; Anders Robin F; Norton Raymond S
A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(12):839-48.
2007: Zhang Min-Min; Green Brad R; Catlin Philip; Fiedler Brian; Azam Layla; Chadwick Ashley; Terlau Heinrich; McArthur Jeff R; French Robert J; Gulyas Josef; Rivier Jean E; Smith Brian J; Norton Raymond S; Olivera Baldomero M; Yoshikami Doju; Bulaj Grzegorz
Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.
The Journal of biological chemistry 2007;282(42):30699-706.
2007: Buczek Olga; Wei Daxiu; Babon Jeffrey J; Yang Xiaodong; Fiedler Brian; Chen Ping; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Biochemistry 2007;46(35):9929-40.
2007: Low Andrew; Chandrashekaran Indu R; Adda Christopher G; Yao Shenggen; Sabo Jennifer K; Zhang Xuecheng; Soetopo Alfreda; Anders Robin F; Norton Raymond S
Merozoite surface protein 2 of Plasmodium falciparum: expression, structure, dynamics, and fibril formation of the conserved N-terminal domain.
Biopolymers 2007;87(1):12-22.
2007: Green Brad R; Catlin Philip; Zhang Min-Min; Fiedler Brian; Bayudan Wendi; Morrison Alex; Norton Raymond S; Smith Brian J; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz
Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity.
Chemistry & biology 2007;14(4):399-407.
2007: Chandrashekaran Indu R; Yao Shenggen; Wang Chunxiao C; Bansal Paramjit S; Alewood Paul F; Forbes Briony E; Wallace John C; Bach Leon A; Norton Raymond S
The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs.
Biochemistry 2007;46(11):3065-74.
2007: Sabo Jennifer K; Keizer David W; Feng Zhi-Ping; Casey Joanne L; Parisi Kathy; Coley Andrew M; Foley Michael; Norton Raymond S
Mimotopes of apical membrane antigen 1: Structures of phage-derived peptides recognized by the inhibitory monoclonal antibody 4G2dc1 and design of a more active analogue.
Infection and immunity 2007;75(1):61-73.
2006: Han Pengfei; Zhang Xiuzhen; Norton Raymond S; Feng Zhi-Ping
Predicting disordered regions in proteins based on decision trees of reduced amino acid composition.
Journal of computational biology : a journal of computational molecular cell biology 2006;13(10):1723-34.
2006: Yao Shenggen; Liu Ming S; Masters Seth L; Zhang Jian-Guo; Babon Jeffrey J; Nicola Nicos A; Nicholson Sandra E; Norton Raymond S
Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops.
Protein science : a publication of the Protein Society 2006;15(12):2761-72.
2006: Kuang Zhihe; Yao Shenggen; Keizer David W; Wang Chunxiao C; Bach Leon A; Forbes Briony E; Wallace John C; Norton Raymond S
Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2).
Journal of molecular biology 2006;364(4):690-704.
2006: Feng Zhi-Ping; Zhang Xiuzhen; Han Pengfei; Arora Neeraj; Anders Robin F; Norton Raymond S
Abundance of intrinsically unstructured proteins in P. falciparum and other apicomplexan parasite proteomes.
Molecular and biochemical parasitology 2006;150(2):256-67.
2006: Norton Raymond S; Olivera Baldomero M
Conotoxins down under.
Toxicon : official journal of the International Society on Toxinology 2006;48(7):780-98.
2006: Babon Jeffrey J; McManus Edward J; Yao Shenggen; DeSouza David P; Mielke Lisa A; Sprigg Naomi S; Willson Tracy A; Hilton Douglas J; Nicola Nicos A; Baca Manuel; Nicholson Sandra E; Norton Raymond S
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.
Molecular cell 2006;22(2):205-16.
2006: Drechsler Alison; Potrich Cristina; Sabo Jennifer K; Frisanco Mattia; Guella Graziano; Dalla Serra Mauro; Anderluh Gregor; Separovic Frances; Norton Raymond S
Structure and activity of the N-terminal region of the eukaryotic cytolysin equinatoxin II.
Biochemistry 2006;45(6):1818-28.
2006: Masters Seth L; Yao Shenggen; Willson Tracy A; Zhang Jian-Guo; Palmer Kirsten R; Smith Brian J; Babon Jeffrey J; Nicola Nicos A; Norton Raymond S; Nicholson Sandra E
The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.
Nature structural & molecular biology 2006;13(1):77-84.
2005: Babon Jeffrey J; Yao Shenggen; DeSouza David P; Harrison Christopher F; Fabri Louis J; Liepinsh Edvards; Scrofani Sergio D; Baca Manuel; Norton Raymond S
Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain.
The FEBS journal 2005;272(23):6120-30.
2005: Harris Karen S; Casey Joanne L; Coley Andrew M; Masciantonio Rosella; Sabo Jennifer K; Keizer David W; Lee Erinna F; McMahon Andrew; Norton Raymond S; Anders Robin F; Foley Michael
Binding hot spot for invasion inhibitory molecules on Plasmodium falciparum apical membrane antigen 1.
Infection and immunity 2005;73(10):6981-9.
2005: Feng Zhi-Ping; Keizer David W; Stevenson Rachel A; Yao Shenggen; Babon Jeffrey J; Murphy Vince J; Anders Robin F; Norton Raymond S
Structure and inter-domain interactions of domain II from the blood-stage malarial protein, apical membrane antigen 1.
Journal of molecular biology 2005;350(4):641-56.
2005: Bach Leon A; Headey Stephen J; Norton Raymond S
IGF-binding proteins--the pieces are falling into place.
Trends in endocrinology and metabolism: TEM 2005;16(5):228-34.
2005: Bulaj Grzegorz; West Peter J; Garrett James E; Watkins Maren; Zhang Min-Min; Norton Raymond S; Smith Brian J; Yoshikami Doju; Olivera Baldomero M
Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.
Biochemistry 2005;44(19):7259-65.
2005: Lauth Xavier; Babon Jeffrey J; Stannard Jason A; Singh Satendra; Nizet Victor; Carlberg James M; Ostland Vaughn E; Pennington Michael W; Norton Raymond S; Westerman Mark E
Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections.
The Journal of biological chemistry 2005;280(10):9272-82.
2005: Yao Shenggen; Masters Seth L; Zhang Jian-Guo; Palmer Kirsten R; Babon Jeffrey J; Nicola Nicos A; Nicholson Sandra E; Norton Raymond S
Backbone 1H, 13C and 15N assignments of the 25 kDa SPRY domain-containing SOCS box protein 2 (SSB-2).
Journal of biomolecular NMR 2005;31(1):69-70.
2004: Norton Raymond S; Pennington Michael W; Wulff Heike
Potassium channel blockade by the sea anemone toxin ShK for the treatment of multiple sclerosis and other autoimmune diseases.
Current medicinal chemistry 2004;11(23):3041-52.
2004: Headey Stephen J; Keizer David W; Yao Shenggen; Brasier Geoffrey; Kantharidis Phillip; Bach Leon A; Norton Raymond S
C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II.
Molecular endocrinology (Baltimore, Md.) 2004;18(11):2740-50.
2004: Headey Stephen J; Leeding Kerri S; Norton Raymond S; Bach Leon A
Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding.
Journal of molecular endocrinology 2004;33(2):377-86.
2004: Yao Shenggen; Headey Stephen J; Keizer David W; Bach Leon A; Norton Raymond S
C-terminal domain of insulin-like growth factor (IGF) binding protein 6: conformational exchange and its correlation with IGF-II binding.
Biochemistry 2004;43(35):11187-95.
2004: He Hong; Shehan B Philip; Barnham Kevin J; Norton Raymond S; Shulkes Arthur; Baldwin Graham S
Biological activity and ferric ion binding of fragments of glycine-extended gastrin.
Biochemistry 2004;43(37):11853-61.
2004: Headey Stephen J; Keizer David W; Yao Shenggen; Wallace John C; Bach Leon A; Norton Raymond S
Binding site for the C-domain of insulin-like growth factor (IGF) binding protein-6 on IGF-II; implications for inhibition of IGF actions.
FEBS letters 2004;568(1-3):19-22.
2004: Fairlie W Douglas; Uboldi Alessandro D; McCoubrie Joanne E; Wang Chunxiao C; Lee Erinna F; Yao Shenggen; De Souza David P; Mifsud Sandra; Metcalf Donald; Nicola Nicos A; Norton Raymond S; Baca Manuel
Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling.
The Journal of biological chemistry 2004;279(3):2125-34.
2004: Pannequin Julie; Kovac Suzana; Tantiongco John-Paul; Norton Raymond S; Shulkes Arthur; Barnham Kevin J; Baldwin Graham S
A novel effect of bismuth ions: selective inhibition of the biological activity of glycine-extended gastrin.
The Journal of biological chemistry 2004;279(4):2453-60.
2003: Alewood Dianne; Birinyi-Strachan Liesl C; Pallaghy Paul K; Norton Raymond S; Nicholson Graham M; Alewood Paul F
Synthesis and characterization of delta-atracotoxin-Ar1a, the lethal neurotoxin from venom of the Sydney funnel-web spider (Atrax robustus).
Biochemistry 2003;42(44):12933-40.
2003: Keizer David W; West Peter J; Lee Erinna F; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA.
The Journal of biological chemistry 2003;278(47):46805-13.
2003: Keizer David W; Miles Luke A; Li Felomena; Nair Margie; Anders Robin F; Coley Andrew M; Foley Michael; Norton Raymond S
Structures of phage-display peptides that bind to the malarial surface protein, apical membrane antigen 1, and block erythrocyte invasion.
Biochemistry 2003;42(33):9915-23.
2003: Barnham Kevin J; McKinstry William J; Multhaup Gerd; Galatis Denise; Morton Craig J; Curtain Cyril C; Williamson Nicholas A; White Anthony R; Hinds Mark G; Norton Raymond S; Beyreuther Konrad; Masters Colin L; Parker Michael W; Cappai Roberto
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.
The Journal of biological chemistry 2003;278(19):17401-7.
2003: Headey Stephen J; Yao Shenggen; Parker Nigel J; Kantharidis Phillip; Bach Leon A; Norton Raymond S
1H, 13C and 15N resonance assignments of the C-terminal domain of insulin-like growth factor binding protein-6 (IGFBP-6).
Journal of biomolecular NMR 2003;25(3):251-2.
2002: Pannequin Julie; Barnham Kevin J; Hollande Frederic; Shulkes Arthur; Norton Raymond S; Baldwin Graham S
Ferric ions are essential for the biological activity of the hormone glycine-extended gastrin.
The Journal of biological chemistry 2002;277(50):48602-9.
2002: Miles Luke A; Dy Catherine Y; Nielsen Jake; Barnham Kevin J; Hinds Mark G; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif.
The Journal of biological chemistry 2002;277(45):43033-40.
2002: Lanigan Mark D; Kalman Katalin; Lefievre Yann; Pennington Michael W; Chandy K George; Norton Raymond S
Mutating a critical lysine in ShK toxin alters its binding configuration in the pore-vestibule region of the voltage-gated potassium channel, Kv1.3.
Biochemistry 2002;41(40):11963-71.
2002: Nair Margie; Hinds Mark G; Coley Andrew M; Hodder Anthony N; Foley Michael; Anders Robin F; Norton Raymond S
Structure of domain III of the blood-stage malaria vaccine candidate, Plasmodium falciparum apical membrane antigen 1 (AMA1).
Journal of molecular biology 2002;322(4):741-53.
2002: Hewish Dean R; Barnham Kevin J; Werkmeister Jerome A; Kirkpatrick Alan; Bartone Nicola; Liu Su Ting; Norton Raymond S; Curtain Cyril; Rivetta Donald E
Structure and activity of D-Pro14 melittin.
Journal of protein chemistry 2002;21(4):243-53.
2002: Yao Shenggen; Smith-White Margaret A; Potter Erica K; Norton Raymond S
Stabilization of the helical structure of Y2-selective analogues of neuropeptide Y by lactam bridges.
Journal of medicinal chemistry 2002;45(11):2310-8.
2002: Baell Jonathan B; Harvey Andrew J; Norton Raymond S
Design and synthesis of type-III mimetics of ShK toxin.
Journal of computer-aided molecular design 2002;16(4):245-62.
2002: Hinds Mark G; Zhang Wei; Anderluh Gregor; Hansen Poul Erik; Norton Raymond S
Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation.
Journal of molecular biology 2002;315(5):1219-29.
2001: Baell J B; Forsyth S A; Gable R W; Norton R S; Mulder R J
Design and synthesis of type-III mimetics of omega-conotoxin GVIA.
Journal of computer-aided molecular design 2001;15(12):1119-36.
2001: Lanigan M D; Pennington M W; Lefievre Y; Rauer H; Norton R S
Designed peptide analogues of the potassium channel blocker ShK toxin.
Biochemistry 2001;40(51):15528-37.
2001: Gorman J J; McKimm-Breschkin J L; Norton R S; Barnham K J
Antiviral activity and structural characteristics of the nonglycosylated central subdomain of human respiratory syncytial virus attachment (G) glycoprotein.
The Journal of biological chemistry 2001;276(42):38988-94.
2001: Chandy K G; Cahalan M; Pennington M; Norton R S; Wulff H; Gutman G A
Potassium channels in T lymphocytes: toxins to therapeutic immunosuppressants.
Toxicon : official journal of the International Society on Toxinology 2001;39(9):1269-76.
2001: Curtain C C; Ali F; Volitakis I; Cherny R A; Norton R S; Beyreuther K; Barrow C J; Masters C L; Bush A I; Barnham K J
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits.
The Journal of biological chemistry 2001;276(23):20466-73.
2001: Lanigan M D; Tudor J E; Pennington M W; Norton R S
A helical capping motif in ShK toxin and its role in helix stabilization.
Biopolymers 2001;58(4):422-36.
2001: Thompson A J; Barnham K J; Norton R S; Barrow C J
The Val-210-Ile pathogenic Creutzfeldt-Jakob disease mutation increases both the helical and aggregation propensities of a sequence corresponding to helix-3 of PrP(C).
Biochimica et biophysica acta 2001;1544(1-2):242-54.
2001: Nair M; Hodder A N; Hinds M G; Anders R F; Norton R S
Assignment of 1H, 13C and 15N resonances of domain III of the ectodomain of apical membrane antigen 1 from Plasmodium falciparum.
Journal of biomolecular NMR 2001;19(1):85-6.
2000: Zhang W; Hinds M G; Anderluh G; Hanse P E; Norton R S
Letter to the editor: Sequence-specific resonance assignments of the potent cytolysin equinatoxin II.
Journal of biomolecular NMR 2000;18(3):281-2.
2000: Pallaghy P K; He W; Jimenez E C; Olivera B M; Norton R S
Structures of the contryphan family of cyclic peptides. Role of electrostatic interactions in cis-trans isomerism.
Biochemistry 2000;39(42):12845-52.
2000: Pallaghy P K; Norton R S
The cyclic contryphan motif CPxXPXC, a robust scaffold potentially useful as an omega-conotoxin mimic.
Biopolymers 2000;54(3):173-9.
2000: Yao S; Smith D K; Hinds M G; Zhang J G; Nicola N A; Norton R S
Backbone dynamics measurements on leukemia inhibitory factor, a rigid four-helical bundle cytokine.
Protein science : a publication of the Protein Society 2000;9(4):671-82.
2000: Yao S; Howlett G J; Norton R S
Peptide self-association in aqueous trifluoroethanol monitored by pulsed field gradient NMR diffusion measurements.
Journal of biomolecular NMR 2000;16(2):109-19.
2000: Rauer H; Lanigan M D; Pennington M W; Aiyar J; Ghanshani S; Cahalan M D; Norton R S; Chandy K G
Structure-guided transformation of charybdotoxin yields an analog that selectively targets Ca(2+)-activated over voltage-gated K(+) channels.
The Journal of biological chemistry 2000;275(2):1201-8.
1999: Barnham K J; Catalfamo F; Pallaghy P K; Howlett G J; Norton R S
Helical structure and self-association in a 13 residue neuropeptide Y Y2 receptor agonist: relationship to biological activity.
Biochimica et biophysica acta 1999;1435(1-2):127-37.
1999: Pennington M W; Lanigan M D; Kalman K; Mahnir V M; Rauer H; McVaugh C T; Behm D; Donaldson D; Chandy K G; Kem W R; Norton R S
Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin.
Biochemistry 1999;38(44):14549-58.
1999: Flinn J P; Pallaghy P K; Lew M J; Murphy R; Angus J A; Norton R S
Role of disulfide bridges in the folding, structure and biological activity of omega-conotoxin GVIA.
Biochimica et biophysica acta 1999;1434(1):177-90.
1999: Pallaghy P K; Melnikova A P; Jimenez E C; Olivera B M; Norton R S
Solution structure of contryphan-R, a naturally occurring disulfide-bridged octapeptide containing D-tryptophan: comparison with protein loops.
Biochemistry 1999;38(35):11553-9.
1999: Flinn J P; Pallaghy P K; Lew M J; Murphy R; Angus J A; Norton R S
Roles of key functional groups in omega-conotoxin GVIA synthesis, structure and functional assay of selected peptide analogues.
European journal of biochemistry / FEBS 1999;262(2):447-55.
1999: Pallaghy P K; Norton R S
Refined solution structure of omega-conotoxin GVIA: implications for calcium channel binding.
The journal of peptide research : official journal of the American Peptide Society 1999;53(3):343-51.
1999: Temple M D; Hinds M G; Sheumack D D; Howden M E; Norton R S
1H NMR study of robustoxin, the lethal neurotoxin from the funnel web spider Atrax robustus.
Toxicon : official journal of the International Society on Toxinology 1999;37(3):485-506.
1998: Kalman K; Pennington M W; Lanigan M D; Nguyen A; Rauer H; Mahnir V; Paschetto K; Kem W R; Grissmer S; Gutman G A; Christian E P; Cahalan M D; Norton R S; Chandy K G
ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.
The Journal of biological chemistry 1998;273(49):32697-707.
1998: Yao S; Torres A M; Azad A A; Macreadie I G; Norton R S
Solution structure of peptides from HIV-1 Vpr protein that cause membrane permeabilization and growth arrest.
Journal of peptide science : an official publication of the European Peptide Society 1998;4(7):426-35.
1998: Norton R S; Pallaghy P K
The cystine knot structure of ion channel toxins and related polypeptides.
Toxicon : official journal of the International Society on Toxinology 1998;36(11):1573-83.
1998: Barnham K J; Torres A M; Alewood D; Alewood P F; Domagala T; Nice E C; Norton R S
Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein science : a publication of the Protein Society 1998;7(8):1738-49.
1998: Hinds M G; Maurer T; Zhang J G; Nicola N A; Norton R S
Solution structure of leukemia inhibitory factor.
The Journal of biological chemistry 1998;273(22):13738-45.
1998: Tudor J E; Pennington M W; Norton R S
Ionisation behaviour and solution properties of the potassium-channel blocker ShK toxin.
European journal of biochemistry / FEBS 1998;251(1-2):133-41.
1997: Pallaghy P K; Alewood D; Alewood P F; Norton R S
Solution structure of robustoxin, the lethal neurotoxin from the funnel-web spider Atrax robustus.
FEBS letters 1997;419(2-3):191-6.
1997: Hinds M G; Norton R S
NMR spectroscopy of peptides and proteins. Practical considerations.
Molecular biotechnology 1997;7(3):315-31.
1997: Barnham K J; Dyke T R; Kem W R; Norton R S
Structure of neurotoxin B-IV from the marine worm Cerebratulus lacteus: a helical hairpin cross-linked by disulphide bonding.
Journal of molecular biology 1997;268(5):886-902.
1997: Barnham K J; Monks S A; Hinds M G; Azad A A; Norton R S
Solution structure of a polypeptide from the N terminus of the HIV protein Nef.
Biochemistry 1997;36(20):5970-80.
1997: Lew M J; Flinn J P; Pallaghy P K; Murphy R; Whorlow S L; Wright C E; Norton R S; Angus J A
Structure-function relationships of omega-conotoxin GVIA. Synthesis, structure, calcium channel binding, and functional assay of alanine-substituted analogues.
The Journal of biological chemistry 1997;272(18):12014-23.
1997: Hinds M G; Maurer T; Zhang J G; Nicola N A; Norton R S
Resonance assignments, secondary structure and topology of leukaemia inhibitory factor in solution.
Journal of biomolecular NMR 1997;9(2):113-26.
1996: Monks S A; Karagianis G; Howlett G J; Norton R S
Solution structure of human neuropeptide Y.
Journal of biomolecular NMR 1996;8(4):379-90.
1996: Monks S A; Norton R S; Curtain C C; Berliner L J
Preparation and characterization of a biologically active spin-labeled sea anemone toxin.
Journal of protein chemistry 1996;15(5):427-34.
1996: Tudor J E; Pallaghy P K; Pennington M W; Norton R S
Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone.
Nature structural biology 1996;3(4):317-20.
1996: Dyke T R; Duggan B M; Pennington M W; Byrnes M E; Kem W R; Norton R S
Synthesis and structural characterisation of analogues of the potassium channel blocker charybdotoxin.
Biochimica et biophysica acta 1996;1292(1):31-8.
1995: Monks S A; Pallaghy P K; Scanlon M J; Norton R S
Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-A.
Structure (London, England : 1993) 1995;3(8):791-803.
1995: Morton C J; Bai H; Zhang J G; Hammacher A; Norton R S; Simpson R J; Mabbutt B C
NMR studies of the solution properties of recombinant murine interleukin-6.
Biochimica et biophysica acta 1995;1249(2):189-203.
1995: Kortt A A; Guthrie R E; Hinds M G; Power B E; Ivancic N; Caldwell J B; Gruen L C; Norton R S; Hudson P J
Solution properties of Escherichia coli-expressed VH domain of anti-neuraminidase antibody NC41.
Journal of protein chemistry 1995;14(3):167-78.
1995: Pallaghy P K; Scanlon M J; Monks S A; Norton R S
Three-dimensional structure in solution of the polypeptide cardiac stimulant anthopleurin-A.
Biochemistry 1995;34(11):3782-94.
1995: Mulhern T D; Howlett G J; Reid G E; Simpson R J; McColl D J; Anders R F; Norton R S
Solution structure of a polypeptide containing four heptad repeat units from a merozoite surface antigen of Plasmodium falciparum.
Biochemistry 1995;34(11):3479-91.
1995: Gould A R; Norton R S
Chemical modification of cationic groups in the polypeptide cardiac stimulant anthopleurin-A.
Toxicon : official journal of the International Society on Toxinology 1995;33(2):187-99.
1994: Pallaghy P K; Nielsen K J; Craik D J; Norton R S
A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides.
Protein science : a publication of the Protein Society 1994;3(10):1833-9.
1994: Manoleras N; Norton R S
Three-dimensional structure in solution of neurotoxin III from the sea anemone Anemonia sulcata.
Biochemistry 1994;33(37):11051-61.
1994: Smith D K; Treutlein H R; Maurer T; Owczarek C M; Layton M J; Nicola N A; Norton R S
Homology modelling and 1H NMR studies of human leukaemia inhibitory factor.
FEBS letters 1994;350(2-3):275-80.
1994: Scanlon M J; Norton R S
Multiple conformations of the sea anemone polypeptide anthopleurin-A in solution.
Protein science : a publication of the Protein Society 1994;3(7):1121-4.
1994: Monks S A; Gould A R; Lumley P E; Alewood P F; Kem W R; Goss N H; Norton R S
Limited proteolysis study of structure-function relationships in Sh I, a polypeptide neurotoxin from a sea anemone.
Biochimica et biophysica acta 1994;1207(1):93-101.
1994: Pennington M W; Zadenberg I; Byrnes M E; Norton R S; Kem W R
Synthesis of the cardiac inotropic polypeptide anthopleurin-A.
International journal of peptide and protein research 1994;43(5):463-70.
1994: Morton C J; Simpson R J; Norton R S
Solution structure of synthetic peptides corresponding to the C-terminal helix of interleukin-6.
European journal of biochemistry / FEBS 1994;219(1-2):97-107.
1994: Maurer T; Smith D K; Owczarek C M; Layton M J; Zhang J G; Nicola N A; Norton R S
NMR studies of a murine-human chimera of leukaemia inhibitory factor (LIF). Comparison with human LIF.
Growth factors (Chur, Switzerland) 1994;11(4):271-6.
1994: Hinds M G; Norton R S
NMR spectroscopy of peptides and proteins.
Methods in molecular biology (Clifton, N.J.) 1994;36():131-54.
1993: Pallaghy P K; Duggan B M; Pennington M W; Norton R S
Three-dimensional structure in solution of the calcium channel blocker omega-conotoxin.
Journal of molecular biology 1993;234(2):405-20.
1993: Wilcox G R; Fogh R H; Norton R S
Refined structure in solution of the sea anemone neurotoxin ShI.
The Journal of biological chemistry 1993;268(33):24707-19.
1993: Ward L D; Hammacher A; Zhang J G; Weinstock J; Yasukawa K; Morton C J; Norton R S; Simpson R J
Role of the C-terminus in the activity, conformation, and stability of interleukin-6.
Protein science : a publication of the Protein Society 1993;2(9):1472-81.
1993: Norton R S; Cross K; Braach-Maksvytis V; Wachter E
1H-n.m.r. study of the solution properties and secondary structure of neurotoxin III from the sea anemone Anemonia sulcata.
The Biochemical journal 1993;293 ( Pt 2)():545-51.
1993: Hinds M G; Norton R S
Sequential 1H-NMR assignments of neurotoxin III from the sea anemone Heteractis macrodactylus and structural comparison with related toxins.
Journal of protein chemistry 1993;12(3):371-8.
1992: Hansen P E; Kem W R; Bieber A L; Norton R S
1H-NMR study of neurotoxin B-IV from the marine worm Cerebratulus lacteus. Solution properties, sequence-specific resonance assignments, secondary structure and global fold.
European journal of biochemistry / FEBS 1992;210(1):231-40.
1992: Gould A R; Mabbutt B C; Llewellyn L E; Goss N H; Norton R S
Linear and cyclic peptide analogues of the polypeptide cardiac stimulant, anthopleurin-A. 1H-NMR and biological activity studies.
European journal of biochemistry / FEBS 1992;206(3):641-51.
1992: Norton R S; Macek P; Reid G E; Simpson R J
Relationship between the cytolysins tenebrosin-C from Actinia tenebrosa and equinatoxin II from Actinia equina.
Toxicon : official journal of the International Society on Toxinology 1992;30(1):13-23.
1991: Llewellyn L E; Norton R S
Binding of the sea anemone polypeptide BDS II to the voltage-gated sodium channel.
Biochemistry international 1991;24(5):937-46.
1991: Norton R S
Structure and structure-function relationships of sea anemone proteins that interact with the sodium channel.
Toxicon : official journal of the International Society on Toxinology 1991;29(9):1051-84.
1990: Pennington M W; Kem W R; Norton R S; Dunn B M
Chemical synthesis of a neurotoxic polypeptide from the sea anemone Stichodactyla helianthus.
International journal of peptide and protein research 1990;36(4):335-43.
1990: Fogh R H; Kem W R; Norton R S
Solution structure of neurotoxin I from the sea anemone Stichodactyla helianthus. A nuclear magnetic resonance, distance geometry, and restrained molecular dynamics study.
The Journal of biological chemistry 1990;265(22):13016-28.
1990: Simpson R J; Reid G E; Moritz R L; Morton C; Norton R S
Complete amino acid sequence of tenebrosin-C, a cardiac stimulatory and haemolytic protein from the sea anemone Actinia tenebrosa.
European journal of biochemistry / FEBS 1990;190(2):319-28.
1990: Gould A R; Mabbutt B C; Norton R S
Structure-function relationships in the polypeptide cardiac stimulant, anthopleurin-A. Effects of limited proteolysis by trypsin.
European journal of biochemistry / FEBS 1990;189(1):145-53.
1990: Mabbutt B C; Norton R S
Sequential 1H-NMR assignments and secondary structure of the sea anemone polypeptide anthopleurin-A.
European journal of biochemistry / FEBS 1990;187(3):555-63.
1990: Galettis P; Norton R S
Biochemical and pharmacological studies of the mechanism of action of tenebrosin-C, a cardiac stimulatory and haemolytic protein from the sea anemone, Actinia tenebrosa.
Toxicon : official journal of the International Society on Toxinology 1990;28(6):695-706.
1990: Norton R S; Bobek G; Ivanov J O; Thomson M; Fiala-Beer E; Moritz R L; Simpson R J
Purification and characterisation of proteins with cardiac stimulatory and haemolytic activity from the anemone Actinia tenebrosa.
Toxicon : official journal of the International Society on Toxinology 1990;28(1):29-41.
1989: Torda A E; Norton R S
Proton nmr relaxation study of the dynamics of anthopleurin-A in solution.
Biopolymers 1989;28(3):703-16.
1989: Fogh R H; Mabbutt B C; Kem W R; Norton R S
Sequence-specific 1H NMR assignments and secondary structure in the sea anemone polypeptide Stichodactyla helianthus neurotoxin I.
Biochemistry 1989;28(4):1826-34.
1989: Norton R S; Cossins A I; Kem W R
1H NMR study of the solution properties of the polypeptide neurotoxin I from the sea anemone Stichodactyla helianthus.
Biochemistry 1989;28(4):1820-6.
1988: Torda A E; Mabbutt B C; van Gunsteren W F; Norton R S
Backbone folding of the polypeptide cardiac stimulant anthopleurin-A determined by nuclear magnetic resonance, distance geometry and molecular dynamics.
FEBS letters 1988;239(2):266-70.
1987: Thomson M; Moritz R L; Simpson R J; Norton R S
Tenebrosin-A, a new cardiostimulant protein from the Australian sea anemone Actinia tenebrosa.
Biochemistry international 1987;15(4):711-8.
1987: Torda A E; Norton R S
Amide proton exchange rates in cardioactive sea anemone polypeptides.
Biochemistry international 1987;15(3):659-66.
1985: Gruen L C; Norton R S
Role of aspartate residues in the cardiac stimulatory activity of anthopleurin-A.
Biochemistry international 1985;11(1):69-76.
1985: Torda A E; Baldwin G S; Norton R S
High-resolution proton nuclear magnetic resonance studies of human gastrin.
Biochemistry 1985;24(7):1720-7.

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