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Hans Nottet

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HIV-1

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Hans S L M Nottet; Sabine J van Dijk; Ewout B Fanoy; Irma W Goedegebuure; Dorien de Jong; Nienke Vrisekoop; Debbie van Baarle; Valerie Boltz; Sarah Palmer; Jan C C Borleffs; Charles A B Boucher
HIV-1 can persist in aged memory CD4+ T lymphocytes with minimal signs of evolution after 8.3 years of effective highly active antiretroviral therapy.
Leonie A Boven; Farshid Noorbakhsh; Gerben Bouma; Ruurd van der Zee; Diana Vargas; CARLOS PARDO-VILLAMIZAR; justin charles mcarthur; Hans S L M Nottet; Christopher Power
Brain-derived human immunodeficiency virus-1 Tat exerts differential effects on LTR transactivation and neuroimmune activation.
N A C H Brabers; Hans S L M Nottet
Role of the pro-inflammatory cytokines TNF-alpha and IL-1beta in HIV-associated dementia.

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All Publications

2009: Hans S L M Nottet; Sabine J van Dijk; Ewout B Fanoy; Irma W Goedegebuure; Dorien de Jong; Nienke Vrisekoop; Debbie van Baarle; Valerie Boltz; Sarah Palmer; Jan C C Borleffs; Charles A B Boucher
HIV-1 can persist in aged memory CD4+ T lymphocytes with minimal signs of evolution after 8.3 years of effective highly active antiretroviral therapy.
Journal of acquired immune deficiency syndromes (1999) 2009;50(4):345-53.
2007: Leonie A Boven; Farshid Noorbakhsh; Gerben Bouma; Ruurd van der Zee; Diana Vargas; CARLOS PARDO-VILLAMIZAR; justin charles mcarthur; Hans S L M Nottet; Christopher Power
Brain-derived human immunodeficiency virus-1 Tat exerts differential effects on LTR transactivation and neuroimmune activation.
Journal of neurovirology 2007;13(2):173-84.
2006: N A C H Brabers; Hans S L M Nottet
Role of the pro-inflammatory cytokines TNF-alpha and IL-1beta in HIV-associated dementia.
European journal of clinical investigation 2006;36(7):447-58.
2005: Cândida F Pereira; Karla Rutten; Ruzena Stránská; Marleen C D G Huigen; Piet C Aerts; Raoul J de Groot; Herman F Egberink; Rob Schuurman; Hans S L M Nottet
Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS).
International journal of antimicrobial agents 2005;25(5):419-26.
2004: Niki A Georgiou; Tjomme van der Bruggen; Maroeska Oudshoorn; Prim de Bie; Christine A Jansen; Hans S L M Nottet; Joannes Marx; B Sweder van Asbeck
Mechanism of inhibition of the human immunodeficiency virus type 1 by the oxygen radical generating agent bleomycin.
Antiviral research 2004;63(2):97-106.
2004: Marleen C D G Huigen; W Kamp; Hans S L M Nottet
Multiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infection.
European journal of clinical investigation 2004;34(1):57-66.
2003: Cândida F Pereira; Judith T M L Paridaen; Karla Rutten; Marleen C D G Huigen; Marja van de Bovenkamp; Jeena Middel; Nancy Beerens; Ben Berkhout; Rob Schuurman; Lawrence J Marnett; Jan Verhoef; Hans S L M Nottet
Aspirin-like molecules that inhibit human immunodeficiency virus 1 replication.
Antiviral research 2003;58(3):253-63.
2003: Cândida F Pereira; Judith T M L Paridaen; Marja van de Bovenkamp; Jeena Middel; Jan Verhoef; Hans S L M Nottet
APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro.
The Journal of antimicrobial chemotherapy 2003;51(5):1181-9.
2002: Marja van de Bovenkamp; Hans S L M Nottet; Cândida F Pereira
Interactions of human immunodeficiency virus-1 proteins with neurons: possible role in the development of human immunodeficiency virus-1-associated dementia.
European journal of clinical investigation 2002;32(8):619-27.
2002: Hessel A Smits; Annemarie Rijsmus; Joyce H van Loon; Jesse W Y Wat; Jan Verhoef; Leonie A Boven; Hans S L M Nottet
Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes.
Journal of neuroimmunology 2002;127(1-2):160-8.
2002: J V R B Hendriksen; Hans S L M Nottet; Hessel A Smits
Secretases as targets for drug design in Alzheimer's disease.
European journal of clinical investigation 2002;32(1):60-8.
2001: Niki A Georgiou; Tjomme van der Bruggen; Christine A Jansen; Maroeska Oudshoorn; Hans S L M Nottet; Joannes Marx; B Sweder van Asbeck
The chemotherapeutic agent bleomycin in a two-drug combination with zidovudine, ritonavir or indinavir synergistically inhibits HIV Type-1 replication in peripheral blood lymphocytes.
International journal of antimicrobial agents 2001;18(6):513-8.
2001: W Kamp; E C Breij; Hans S L M Nottet; M B Berk
Interactions between major histocompatibility complex class II surface expression and HIV: implications for pathogenesis.
European journal of clinical investigation 2001;31(11):984-91.
2001: Hessel A Smits; A J van Beelen; NM de Vos; A Rijsmus; Tjomme van der Bruggen; Jan Verhoef; Freek Van Muiswinkel; Hans S L M Nottet
Activation of human macrophages by amyloid-beta is attenuated by astrocytes.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(11):6869-76.
2001: Cândida F Pereira; Jeena Middel; G Jansen; Jan Verhoef; Hans S L M Nottet
Enhanced expression of fractalkine in HIV-1 associated dementia.
Journal of neuroimmunology 2001;115(1-2):168-75.
2001: Hessel A Smits; NM de Vos; Jesse W Y Wat; Tjomme van der Bruggen; Jan Verhoef; Hans S L M Nottet
Intracellular pathways involved in TNF-alpha and superoxide anion release by Abeta(1-42)-stimulated primary human macrophages.
Journal of neuroimmunology 2001;115(1-2):144-51.
2001: B Sweder van Asbeck; Niki A Georgiou; Tjomme van der Bruggen; Maroeska Oudshoorn; Hans S L M Nottet; Joannes Marx
Anti-HIV effect of iron chelators: different mechanisms involved.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2001;20(3):141-7.
2000: Tjomme van der Bruggen; Niki A Georgiou; Maroeska Oudshoorn; Hans S L M Nottet; Joannes Marx; B Sweder van Asbeck
The effect of deoxynucleosides on cell proliferation of peripheral blood lymphocytes treated with deferoxamine or hydroxyurea.
Transfusion science 2000;23(3):243-4.
2000: Leonie A Boven; Lisette Montagne; Hans S L M Nottet; Christianne J M De Groot
Macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions.
Clinical and experimental immunology 2000;122(2):257-63.
2000: Leonie A Boven; Jeena Middel; E C Breij; D Schotte; Jan Verhoef; C Soderland; Hans S L M Nottet
Interactions between HIV-infected monocyte-derived macrophages and human brain microvascular endothelial cells result in increased expression of CC chemokines.
Journal of neurovirology 2000;6(5):382-9.
2000: Cândida F Pereira; Leonie A Boven; Jeena Middel; Jan Verhoef; Hans S L M Nottet
Induction of cyclooxygenase-2 expression during HIV-1-infected monocyte-derived macrophage and human brain microvascular endothelial cell interactions.
Journal of leukocyte biology 2000;68(3):423-8.
2000: W Kamp; M B Berk; C J Visser; Hans S L M Nottet
Mechanisms of HIV-1 to escape from the host immune surveillance.
European journal of clinical investigation 2000;30(8):740-6.
2000: Leonie A Boven; Jeena Middel; Jan Verhoef; Christianne J M De Groot; Hans S L M Nottet
Monocyte infiltration is highly associated with loss of the tight junction protein zonula occludens in HIV-1-associated dementia.
Neuropathology and applied neurobiology 2000;26(4):356-60.
2000: Hessel A Smits; Leonie A Boven; Cândida F Pereira; Jan Verhoef; Hans S L M Nottet
Role of macrophage activation in the pathogenesis of Alzheimer's disease and human immunodeficiency virus type 1-associated dementia.
European journal of clinical investigation 2000;30(6):526-35.
2000: Teunis B H Geijtenbeek; D S Kwon; Ruurd Torensma; Sandra J van Vliet; Gerard van Duijnhoven; Jeena Middel; I L Cornelissen; Hans S L M Nottet; Vineet N KewalRamani; Dan R Littman; Carl G Figdor; Yvette van Kooyk
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells.
Cell 2000;100(5):587-97.
2000: Niki A Georgiou; Tjomme van der Bruggen; Maroeska Oudshoorn; Hans S L M Nottet; Joannes Marx; B Sweder van Asbeck
Inhibition of human immunodeficiency virus type 1 replication in human mononuclear blood cells by the iron chelators deferoxamine, deferiprone, and bleomycin.
The Journal of infectious diseases 2000;181(2):484-90.
2000: JM Orendi; Hans S L M Nottet; NM de Vos; M R Visser; Harm Snippe; Charles A B Boucher; Jan Verhoef
Hydroxyurea interferes with antigen-dependent T-cell activation in vitro.
European journal of clinical investigation 2000;30(2):162-6.
1999: Hans S L M Nottet
Interactions between macrophages and brain microvascular endothelial cells: role in pathogenesis of HIV-1 infection and blood - brain barrier function.
Journal of neurovirology 1999;5(6):659-69.
1999: Leonie A Boven; Tjomme van der Bruggen; B Sweder van Asbeck; Joannes Marx; Hans S L M Nottet
Potential role of CCR5 polymorphism in the development of AIDS dementia complex.
FEMS immunology and medical microbiology 1999;26(3-4):243-7.
1999: Leonie A Boven; Jeena Middel; P Portegies; Jan Verhoef; G H Jansen; Hans S L M Nottet
Overexpression of nerve growth factor and basic fibroblast growth factor in AIDS dementia complex.
Journal of neuroimmunology 1999;97(1-2):154-62.
1999: Jan Verhoef; Harm Snippe; Hans S L M Nottet
Christiaan Eijkman. First bacteriologist at Utrecht University, Nobel laureate for his work on vitamins.
Antonie van Leeuwenhoek 1999;75(3):165-9.
1999: Freek Van Muiswinkel; S F Raupp; NM de Vos; Hessel A Smits; Jan Verhoef; Piet Eikelenboom; Hans S L M Nottet
The amino-terminus of the amyloid-beta protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages.
Journal of neuroimmunology 1999;96(1):121-30.
1999: Leonie A Boven; L Gomes; Christiane Hery; Françoise Gray; Jan Verhoef; P Portegies; Marc Tardieu; Hans S L M Nottet
Increased peroxynitrite activity in AIDS dementia complex: implications for the neuropathogenesis of HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):4319-27.
1998: IM Fernández; Hana Golding; Barry Benaissa-Trouw; NM de Vos; M Harmsen; Hans S L M Nottet; Basil Golding; Wouter C Puijk; Rob H Meloen; Harm Snippe; CA Kraaijeveld
Induction of HIV-1 IIIb neutralizing antibodies in BALB/c mice by a chimaeric peptide consisting of a T-helper cell epitope of Semliki Forest virus and a B-cell epitope of HIV.
Vaccine 1998;16(20):1936-40.
1998: JM Orendi; A C Bloem; Jan C C Borleffs; F J Wijnholds; NM de Vos; Hans S L M Nottet; M R Visser; Harm Snippe; Jan Verhoef; Charles A B Boucher
Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection.
The Journal of infectious diseases 1998;178(5):1279-87.
1997: A M Been-Tiktak; Carla J C de Haas; Loek de Graaf; Charles A B Boucher; Jan Verhoef; Jan C C Borleffs; Hans S L M Nottet; Rob Schuurman
In-vitro selection of HIV-1 variants resistant to non-nucleoside reverse transcriptase inhibitors in monocyte-derived macrophages.
The Journal of antimicrobial chemotherapy 1997;40(6):847-53.
1997: Hans S L M Nottet; D R Bär; H van Hassel; J Verhoef; Leonie A Boven
Cellular aspects of HIV-1 infection of macrophages leading to neuronal dysfunction in in vitro models for HIV-1 encephalitis.
Journal of leukocyte biology 1997;62(1):107-16.
1997: Hans S L M Nottet; I I Moelans; NM de Vos; Loek de Graaf; M R Visser; Jan Verhoef
N-acetyl-L-cysteine-induced up-regulation of HIV-1 gene expression in monocyte-derived macrophages correlates with increased NF-kappaB DNA binding activity.
Journal of leukocyte biology 1997;61(1):33-9.
1994: Hans S L M Nottet; B Sweder van Asbeck; Loek de Graaf; NM de Vos; Maarten R Visser; Jan Verhoef
Role for oxygen radicals in self-sustained HIV-1 replication in monocyte-derived macrophages: enhanced HIV-1 replication by N-acetyl-L-cysteine.
Journal of leukocyte biology 1994;56(6):702-7.
1994: JM Orendi; Hans S L M Nottet; Maarten R Visser; AF Verheul; Harm Snippe; Jan Verhoef
Enhancement of HIV-1 replication in peripheral blood mononuclear cells by Cryptococcus neoformans is monocyte-dependent but tumour necrosis factor-independent.
AIDS (London, England) 1994;8(4):423-9.
1994: Hans S L M Nottet; M H Oteman; Maarten R Visser; Jan Verhoef
Anti-human immunodeficiency virus type 1 activities of novel non-nucleoside reverse transcriptase inhibitors.
The Journal of antimicrobial chemotherapy 1994;33(2):366-8.
1993: M van der Feltz; Hans S L M Nottet; Maarten R Visser; J C Borleffs; Jan Verhoef
Non-radioactive PCR method for quantification of HIV-infected peripheral blood mononuclear cells in HIV-positive subjects.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1993;12(12):961-4.
1993: Hans S L M Nottet; Loek de Graaf; NM de Vos; L J Bakker; Jos van Strijp; Maarten R Visser; Jan Verhoef
Phagocytic function of monocyte-derived macrophages is not affected by human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 1993;168(1):84-91.
1993: Hans S L M Nottet; I Janse; Loek de Graaf; L J Bakker; Maarten R Visser; Jan Verhoef
Infection of epithelial cell line HEp-2 with human immunodeficiency virus type 1 is CD4 dependent.
Journal of medical virology 1993;40(1):39-43.
1993: Hans S L M Nottet; Loek de Graaf; N Machiel de Vos; L J Bakker; Jos van Strijp; Maarten R Visser; Jan Verhoef
Down-regulation of human immunodeficiency virus type (HIV-1) production after stimulation of monocyte-derived macrophages infected with HIV-1.
The Journal of infectious diseases 1993;167(4):810-7.
1992: Hans S L M Nottet; I Janse; NM de Vos; L J Bakker; Maarten R Visser; Jan Verhoef
Antibody mediated enhancement of HIV-1 infection of an EBV transformed B cell line is CD4 dependent.
European journal of clinical investigation 1992;22(10):670-5.
1992: L J Bakker; Hans S L M Nottet; NM de Vos; Loek de Graaf; Jos van Strijp; Maarten R Visser; Jan Verhoef
Antibodies and complement enhance binding and uptake of HIV-1 by human monocytes.
AIDS (London, England) 1992;6(1):35-41.