FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

David Nutt

Research Profile

Anatomy

Brain

Chemicals & Drugs

Living Beings

Rats

Disorders

Procedures

Co-author Network

Publications

TOP 3
Suresh D Muthukumaraswamy; Jim F M Myers; David J Nutt; Khalid Hamandi; Anne Lingford-Hughes; Sue J Wilson; Krish D Singh
Elevating endogenous GABA levels with GAT-1 blockade modulates evoked but not induced responses in human visual cortex.
Paul R A Stokes; Ben J Watson; Jim Myers; David J Nutt; Daniela Riano Barros; Aaf Benecke; David Erritzoe; Alexander Hammers; Nicola Kalk; Anne Lingford-Hughes
History of cigarette smoking is associated with higher limbic GABAA receptor availability.
Amy Green; Arun Kaul; Jan K Melichar; Emma L Mullings; Marcus R Munafò; David J Nutt; Jacinta O'Shea; Ekta Sharma; Lisa Bennett; Lucy F Donaldson
Opiate agonists and antagonists modulate taste perception in opiate-maintained and recently detoxified subjects.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of David Nutt (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Suresh D Muthukumaraswamy; Jim F M Myers; David J Nutt; Khalid Hamandi; Anne Lingford-Hughes; Sue J Wilson; Krish D Singh
Elevating endogenous GABA levels with GAT-1 blockade modulates evoked but not induced responses in human visual cortex.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013;38(6):1105-12.
2013: Paul R A Stokes; Ben J Watson; Jim Myers; David J Nutt; Daniela Riano Barros; Aaf Benecke; David Erritzoe; Alexander Hammers; Nicola Kalk; Anne Lingford-Hughes
History of cigarette smoking is associated with higher limbic GABAA receptor availability.
NeuroImage 2013;69():70-7.
2013: Amy Green; Arun Kaul; Jan K Melichar; Emma L Mullings; Marcus R Munafò; David J Nutt; Jacinta O'Shea; Ekta Sharma; Lisa Bennett; Lucy F Donaldson
Opiate agonists and antagonists modulate taste perception in opiate-maintained and recently detoxified subjects.
Journal of psychopharmacology (Oxford, England) 2013;27(3):265-75.
2013: David R Owen; Rainer Rupprecht; David J Nutt
Stratified medicine in psychiatry: a worrying example or new opportunity in the treatment of anxiety?
Journal of psychopharmacology (Oxford, England) 2013;27(2):119-22.
2013: Alison Diaper; Colin T Dourish; David J Nutt; Victoria Osman-Hicks; Ann S Rich; Kevin Craig; Gerard Dawson; Jayne E Bailey
Evaluation of the effects of venlafaxine and pregabalin on the carbon dioxide inhalation models of Generalised Anxiety Disorder and panic.
Journal of psychopharmacology (Oxford, England) 2013;27(2):135-45.
2013: Louise M Paterson; Victor W Pike; Birgitte Kornum; David J Nutt; Gitte M Knudsen
5-HT radioligands for human brain imaging with PET and SPECT.
Medicinal research reviews 2013;33(1):54-111.
2012: David J Nutt; Sven Ove Ögren; Jan M van Ree
Neuropsychopharmacology across brain diseases.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2012;22(12):844-6.
2012: D R Quelch; Robin J Tyacke; David J Nutt; Christine A Parker; David Erritzoe
Influence of different cellular environments on [(3)H]DASB radioligand binding.
Synapse (New York, N.Y.) 2012;66(12):1035-9.
2012: Alison Diaper; Colin T Dourish; David J Nutt; Andreas Papadopoulos; Ann S Rich; Gerry R Dawson; Jayne E Bailey
The effect of a clinically effective and non-effective dose of lorazepam on 7.5% CO2-induced anxiety.
Human psychopharmacology 2012;27(6):540-8.
2012: Luke Clark; Alice Egerton; Aaf Benecke; Henrietta Bowden-Jones; Rosanna Michalczuk; David J Nutt; Paola Piccini; Paul R Stokes; Ben J Watson; Kit Wu; Anne Lingford-Hughes
Striatal dopamine D₂/D₃ receptor binding in pathological gambling is correlated with mood-related impulsivity.
NeuroImage 2012;63(1):40-6.
2012: Emma N Mitchell; David J Nutt; Hugh M Marston; Emma S J Robinson
Evaluation of an operant successive negative contrast task as a method to study affective state in rodents.
Behavioural brain research 2012;234(2):155-60.
2012: Alessandro Colasanti; David Erritzoe; Roger N Gunn; Samuel P Hill; Anne R Lingford-Hughes; Christopher J Long; Paul M Matthews; David J Nutt; Darren Quelch; Laurence J Reed; Richard R Reiley; Koen R J Schruers; Graham E Searle; Andri C Tziortzi; Adam D Waldman; Eugenii A Rabiner
Endogenous opioid release in the human brain reward system induced by acute amphetamine administration.
Biological psychiatry 2012;72(5):371-7.
2012: Robin J Tyacke; Christine A Parker; Emma S J Robinson; Emma M Turner; Amy Fisher; Peter Grundt; Alan L Hudson; Stephen M Husbands; David J Nutt
Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2-(4,5-dihydro-1H-imidazol-2-yl)-1- methyl-1H-indole), for the imidazoline₂ binding site.
Synapse (New York, N.Y.) 2012;66(6):542-51.
2012: Helen Bould; Philip Cowen; David J Nutt; Tim J Peters; John Potokar; Nicola Wiles; Glyn Lewis
Does baseline fatigue influence treatment response to reboxetine or citalopram in depression? An open label randomized controlled trial.
Journal of psychopharmacology (Oxford, England) 2012;26(5):663-9.
2012: James F M Myers; David J Nutt; Lula Rosso; Federico E Turkheimer; Ben J Watson; Sue J Wilson; David J Brooks; Nicoletta Clementi; Nicola J Kalk; Anne Lingford-Hughes
Characterisation of the contribution of the GABA-benzodiazepine α1 receptor subtype to [(11)C]Ro15-4513 PET images.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(4):731-44.
2012: Alison Diaper; Eric W Farmer; Marcus R Munafò; David J Nutt; Joanna L White; Jayne E Bailey
The effects of 7.5% carbon dioxide inhalation on task performance in healthy volunteers.
Journal of psychopharmacology (Oxford, England) 2012;26(4):487-96.
2012: Anne Lingford-Hughes; James Myers; David J Brooks; Adrian Feeney; Paul Grasby; Alexander Hammers; Alastair G Reid; Lula Rosso; Lindsay G Taylor; Federico Turkheimer; David J Nutt
A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions.
Journal of psychopharmacology (Oxford, England) 2012;26(2):273-81.
2012: Lindsey I Sinclair; David J Nutt
Anxiolytics.
Handbook of clinical neurology 2012;106():669-79.
2012: Paul R A Stokes; Ben Watson; David J Nutt; Alistair Reid; Alice Egerton; Oliver Howes; Julia M Lappin; Anne Lingford-Hughes
History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability.
Journal of psychopharmacology (Oxford, England) 2012;26(1):144-9.
2011: Jayne E Bailey; Gerard Dawson; Colin T Dourish; David J Nutt
Validating the inhalation of 7.5% CO(2) in healthy volunteers as a human experimental medicine: a model of generalized anxiety disorder (GAD).
Journal of psychopharmacology (Oxford, England) 2011;25(9):1192-8.
2011: Jayne E Bailey; Gerard Dawson; Alison Diaper; Colin T Dourish; Andreas Papadopoulos; Suzanne Phillips; Me Schmidt; P van der Ark; David J Nutt
Preliminary evidence of anxiolytic effects of the CRF(1) receptor antagonist R317573 in the 7.5% CO(2) proof-of-concept experimental model of human anxiety.
Journal of psychopharmacology (Oxford, England) 2011;25(9):1199-206.
2011: B J Watson; S Wilson; L G Taylor; L Griffin; N J Kalk; Anne Lingford-Hughes; Marcus R Munafò; David J Nutt
A pilot study of the effectiveness of D-cycloserine during cue-exposure therapy in abstinent alcohol-dependent subjects.
Psychopharmacology 2011;216(1):121-9.
2011: Andreas Papadopoulos; Yalini Chandramohan; Andrew Collins; Susanne K Droste; David J Nutt; Johannes M H M Reul
GABAergic control of novelty stress-responsive epigenetic and gene expression mechanisms in the rat dentate gyrus.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2011;21(4):316-24.
2011: N J Kalk; David J Nutt; A R Lingford-Hughes
The role of central noradrenergic dysregulation in anxiety disorders: evidence from clinical studies.
Journal of psychopharmacology (Oxford, England) 2011;25(1):3-16.
2011: Kate Seddon; Kelly Morris; J Bailey; John Potokar; Ann Rich; Sue Wilson; Paolo Bettica; David J Nutt
Effects of 7.5% CO2 challenge in generalized anxiety disorder.
Journal of psychopharmacology (Oxford, England) 2011;25(1):43-51.
2011: Sean Hood; Jan K Melichar; L G Taylor; N Kalk; T R Edwards; Dana A Hince; A Lenox-Smith; Anne Lingford-Hughes; David J Nutt
Noradrenergic function in generalized anxiety disorder: impact of treatment with venlafaxine on the physiological and psychological responses to clonidine challenge.
Journal of psychopharmacology (Oxford, England) 2011;25(1):78-86.
2011: Blanca M Bolea-Alamanac; Simon J C Davies; David M Christmas; Hazel Baxter; Sarah Cullum; David J Nutt
Cyproterone to treat aggressivity in dementia: a clinical case and systematic review.
Journal of psychopharmacology (Oxford, England) 2011;25(1):141-5.
2010: Sue J Wilson; David J Nutt; C Alford; Spilios V Argyropoulos; David S Baldwin; Alan Bateson; T C Britton; C Crowe; D-J Dijk; C A Espie; P Gringras; G Hajak; C Idzikowski; A D Krystal; Jon R Nash; H Selsick; A L Sharpley; A G Wade
British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders.
Journal of psychopharmacology (Oxford, England) 2010;24(11):1577-601.
2010: David M Christmas; Abdulla A-B Badawy; Dana Hince; Simon J C Davies; Christopher Probert; Tom Creed; John Smithson; Muhammad Afzal; David J Nutt; John P Potokar
Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome.
Nutrition research (New York, N.Y.) 2010;30(10):678-88.
2010: Peter J Rogers; Christa Hohoff; Susan V Heatherley; Emma L Mullings; Peter J Maxfield; Richard P Evershed; Jürgen Deckert; David J Nutt
Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(9):1973-83.
2010: S J C Davies; M Esler; David J Nutt
Anxiety--bridging the heart/mind divide.
Journal of psychopharmacology (Oxford, England) 2010;24(5):633-8.
2010: Sean Hood; J P Potokar; S J C Davies; Dana A Hince; K Morris; K M Seddon; David J Nutt; S V Argyropoulos
Dopaminergic challenges in social anxiety disorder: evidence for dopamine D3 desensitisation following successful treatment with serotonergic antidepressants.
Journal of psychopharmacology (Oxford, England) 2010;24(5):709-16.
2010: A Papadopoulos; Ann Rich; David J Nutt; Jayne E Bailey
The effects of single dose anxiolytic medication on the CO2 models of anxiety: differentiation of subjective and objective measures.
Journal of psychopharmacology (Oxford, England) 2010;24(5):649-56.
2010: L E Hill; Susanne K Droste; David J Nutt; Astrid C E Linthorst; J M H M Reul
Voluntary exercise alters GABA(A) receptor subunit and glutamic acid decarboxylase-67 gene expression in the rat forebrain.
Journal of psychopharmacology (Oxford, England) 2010;24(5):745-56.
2010: Sean Hood; Dana A Hince; Simon J C Davies; Spilios Argyropoulos; Hayley Robinson; John Potokar; David J Nutt
Effects of acute tryptophan depletion in serotonin reuptake inhibitor-remitted patients with generalized anxiety disorder.
Psychopharmacology 2010;208(2):223-32.
2010: C Durant; D Christmas; David J Nutt
The pharmacology of anxiety.
Current topics in behavioral neurosciences 2010;2():303-30.
2009: David J Nutt; F Mandel; F Baldinetti
Early onset anxiolytic efficacy after a single dose of pregabalin: double-blind, placebo- and active-comparator controlled evaluation using a dental anxiety model.
Journal of psychopharmacology (Oxford, England) 2009;23(8):867-73.
2009: Tim M Williams; Simon J C Davies; Lindsay G Taylor; Mark R C Daglish; Alexander Hammers; David J Brooks; David J Nutt; Anne Lingford-Hughes
Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: an [11C]diprenorphine PET study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2009;19(10):740-8.
2009: Robin L Carhart-Harris; David J Nutt; Marcus R Munafò; David M Christmas; Sue J Wilson
Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls.
Psychopharmacology 2009;206(2):187-96.
2009: Spilios V Argyropoulos; Jane A Hicks; Jon R Nash; Caroline J Bell; Ann S Rich; David J Nutt; Sue Wilson
Redistribution of slow wave activity of sleep during pharmacological treatment of depression with paroxetine but not with nefazodone.
Journal of sleep research 2009;18(3):342-8.
2009: Atsuko Kimura; Robin J Tyacke; James J Robinson; Stephen M Husbands; Michael C W Minchin; David J Nutt; Alan L Hudson
Identification of an imidazoline binding protein: creatine kinase and an imidazoline-2 binding site.
Brain research 2009;1279():21-8.
2009: Lindsey I Sinclair; David M Christmas; Sean Hood; John P Potokar; Andrea Robertson; Andrew Isaac; Shrikant Srivastava; David J Nutt; Simon J C Davies
Antidepressant-induced jitteriness/anxiety syndrome: systematic review.
The British journal of psychiatry : the journal of mental science 2009;194(6):483-90.
2008: Simon J C Davies; Peter R Jackson; Glyn Lewis; Sean Hood; David J Nutt; John P Potokar
Is the association of hypertension and panic disorder explained by clustering of autonomic panic symptoms in hypertensive patients?
Journal of affective disorders 2008;111(2-3):344-50.
2008: Jon R Nash; Peter A Sargent; Eugenii A Rabiner; Sean Hood; Spilios V Argyropoulos; John P Potokar; Paul M Grasby; David J Nutt
Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study.
The British journal of psychiatry : the journal of mental science 2008;193(3):229-34.
2008: Sue Wilson; David J Nutt
Drug treatment of chronic insomnia -- dawn at the end of a long night?
Journal of psychopharmacology (Oxford, England) 2008;22(7):703-6.
2008: Mark R C Daglish; Tim M Williams; Sue J Wilson; Lindsay G Taylor; Chin B Eap; Marc Augsburger; Christian Cédric Giroud; David J Brooks; Judith S Myles; Paul M Grasby; Anne Lingford-Hughes; David J Nutt
Brain dopamine response in human opioid addiction.
The British journal of psychiatry : the journal of mental science 2008;193(1):65-72.
2008: Jayne E Bailey; David J Nutt
GABA-A receptors and the response to CO(2) inhalation - a translational trans-species model of anxiety?
Pharmacology, biochemistry, and behavior 2008;90(1):51-7.
2008: B Sessa; David J Nutt
Reply to letter by Green, Marsden and Fone (2007) about Sessa and Nutt's editorial (MDMA: baby with the bath water) in the November 2007 journal.
Journal of psychopharmacology (Oxford, England) 2008;22(4):457-8.
2008: David J Nutt; C Allgulander; Yves Lecrubier; T Peters; U Wittchen
Establishing non-inferiority in treatment trials in psychiatry: guidelines from an Expert Consensus Meeting.
Journal of psychopharmacology (Oxford, England) 2008;22(4):409-16.
2008: David J Nutt; Anne Lingford-Hughes
Addiction: the clinical interface.
British journal of pharmacology 2008;154(2):397-405.
2008: David J Nutt
Relationship of neurotransmitters to the symptoms of major depressive disorder.
The Journal of clinical psychiatry 2008;69 Suppl E1():4-7.
2008: Alastair G Reid; Mark R C Daglish; Matthew J Kempton; Tim M Williams; Ben Watson; David J Nutt; Anne Lingford-Hughes
Reduced thalamic grey matter volume in opioid dependence is influenced by degree of alcohol use: a voxel-based morphometry study.
Journal of psychopharmacology (Oxford, England) 2008;22(1):7-10.
2008: David J Nutt; Michael Sharpe
Uncritical positive regard? Issues in the efficacy and safety of psychotherapy.
Journal of psychopharmacology (Oxford, England) 2008;22(1):3-6.
2007: David J Nutt; Marie Besson; Sue J Wilson; Gerard Dawson; Anne Lingford-Hughes
Blockade of alcohol's amnestic activity in humans by an alpha5 subtype benzodiazepine receptor inverse agonist.
Neuropharmacology 2007;53(7):810-20.
2007: Ben Sessa; David J Nutt
MDMA, politics and medical research: have we thrown the baby out with the bathwater?
Journal of psychopharmacology (Oxford, England) 2007;21(8):787-91.
2007: Sue Wilson; David J Nutt
Management of insomnia: treatments and mechanismsi.
The British journal of psychiatry : the journal of mental science 2007;191():195-7.
2007: J E Bailey; A Papadopoulos; Anne Lingford-Hughes; David J Nutt
D-Cycloserine and performance under different states of anxiety in healthy volunteers.
Psychopharmacology 2007;193(4):579-85.
2007: Susan P Hume; Anne Lingford-Hughes; Valerie Nataf; Ella Hirani; Rabia Ahmad; Andrew N Davies; David J Nutt
Low sensitivity of the positron emission tomography ligand [11C]diprenorphine to agonist opiates.
The Journal of pharmacology and experimental therapeutics 2007;322(2):661-7.
2007: Haya Abu Ghazaleh; Margaret D Lalies; Stephen M Husbands; David J Nutt; Alan L Hudson
The effect of 1-(4,5-dihydro-1H-imidazol-2-yl) isoquinoline on monoamine release and turnover in the rat frontal cortex.
Neuroscience letters 2007;422(2):109-13.
2007: Tim M Williams; Mark R C Daglish; Anne Lingford-Hughes; Lindsay G Taylor; Alexander Hammers; David J Brooks; Paul M Grasby; Judith S Myles; David J Nutt
Brain opioid receptor binding in early abstinence from opioid dependence: positron emission tomography study.
The British journal of psychiatry : the journal of mental science 2007;191():63-9.
2007: David J Nutt; Koen Demyttenaere; Zoltan Janka; Trond Aarre; Michel Bourin; Pier Luigi Canonico; Jose Luis Carrasco; Steven Stahl
The other face of depression, reduced positive affect: the role of catecholamines in causation and cure.
Journal of psychopharmacology (Oxford, England) 2007;21(5):461-71.
2007: David J Nutt
Rob Kerwin--an appreciation.
Journal of psychopharmacology (Oxford, England) 2007;21(3):237.
2007: Louise M Paterson; Sue J Wilson; David J Nutt; Peter H Hutson; Magnus Ivarsson
A translational, caffeine-induced model of onset insomnia in rats and healthy volunteers.
Psychopharmacology 2007;191(4):943-50.
2007: David J Nutt; Leslie A King; William Saulsbury; Colin Blakemore
Development of a rational scale to assess the harm of drugs of potential misuse.
Lancet 2007;369(9566):1047-53.
2007: Spilios V Argyropoulos; George B Ploubidis; Tamsin S Wright; Marisha E Palm; Sean Hood; Jon R Nash; A Clare Taylor; Sam W Forshall; Ian M Anderson; David J Nutt; John P Potokar
Development and validation of the Generalized Anxiety Disorder Inventory (GADI).
Journal of psychopharmacology (Oxford, England) 2007;21(2):145-52.
2007: Louise M Paterson; Robin J Tyacke; Emma S J Robinson; David J Nutt; Alan L Hudson
In vitro and in vivo effect of BU99006 (5-isothiocyanato-2-benzofuranyl-2-imidazoline) on I2 binding in relation to MAO: evidence for two distinct I2 binding sites.
Neuropharmacology 2007;52(2):395-404.
2007: David J Nutt; Ronald C Kessler; Jordi Alonso; Alastair Benbow; Yves Lecrubier; Jean-Pierre Lépine; David Mechanic; Andre Tylee
Consensus statement on the benefit to the community of ESEMeD (European Study of the Epidemiology of Mental Disorders) survey data on depression and anxiety.
The Journal of clinical psychiatry 2007;68 Suppl 2():42-8.
2007: David J Nutt; K Fone; Philip Asherson; D Bramble; P Hill; K Matthews; K A Morris; Paramala Santosh; E Sonuga-Barke; E Taylor; M Weiss; S Young
Evidence-based guidelines for management of attention-deficit/hyperactivity disorder in adolescents in transition to adult services and in adults: recommendations from the British Association for Psychopharmacology.
Journal of psychopharmacology (Oxford, England) 2007;21(1):10-41.
2007: Jayne E Bailey; Adrian Kendrick; Alison Diaper; John P Potokar; David J Nutt
A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers.
Journal of psychopharmacology (Oxford, England) 2007;21(1):42-9.
2006: Tom P Heath; Jan K Melichar; David J Nutt; Lucy F Donaldson
Human taste thresholds are modulated by serotonin and noradrenaline.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(49):12664-71.
2006: Hayley M Robinson; Sean Hood; Caroline J Bell; David J Nutt
Dopamine and social anxiety disorder.
Revista brasileira de psiquiatria (São Paulo, Brazil : 1999) 2006;28(4):263-4.
2006: Jonathan Shufflebotham; Sean Hood; Julie Hendry; Dana A Hince; Kelly Morris; David J Nutt; C S J Probert; John P Potokar
Acute tryptophan depletion alters gastrointestinal and anxiety symptoms in irritable bowel syndrome.
The American journal of gastroenterology 2006;101(11):2582-7.
2006: David J Nutt; Dan Stein
Understanding the neurobiology of comorbidity in anxiety disorders.
CNS spectrums 2006;11(10 Suppl 12):13-20.
2006: Franciszek Saczewski; Piotr Tabin; Robin J Tyacke; Alys Maconie; Jaroslaw Saczewski; Anita Kornicka; David J Nutt; Alan L Hudson
2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic alpha2 receptor ligands.
Bioorganic & medicinal chemistry 2006;14(19):6679-85.
2006: Simon J C Davies; Sean Hood; Spilios V Argyropoulos; Kelly Morris; Caroline Bell; Harry J Witchel; Peter R Jackson; David J Nutt; John P Potokar
Depleting serotonin enhances both cardiovascular and psychological stress reactivity in recovered patients with anxiety disorders.
Journal of clinical psychopharmacology 2006;26(4):414-8.
2006: David J Nutt; Spilios V Argyropoulos; Sean Hood; John P Potokar
Generalized anxiety disorder: A comorbid disease.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2006;16 Suppl 2():S109-18.
2006: David J Nutt
Alcohol alternatives--a goal for psychopharmacology?
Journal of psychopharmacology (Oxford, England) 2006;20(3):318-20.
2006: Anne Lingford-Hughes; Mark R C Daglish; B J Stevenson; Adrian Feeney; S A Pandit; Steven J Wilson; Judith S Myles; Paul M Grasby; David J Nutt
Imaging alcohol cue exposure in alcohol dependence using a PET 15O-H2O paradigm: results from a pilot study.
Addiction biology 2006;11(1):107-15.
2006: Neil J Anderson; Isabelle Seif; David J Nutt; Alan L Hudson; Emma S J Robinson
Autoradiographical distribution of imidazoline binding sites in monoamine oxidase A deficient mice.
Journal of neurochemistry 2006;96(6):1551-9.
2006: Neil J Anderson; Robin J Tyacke; Stephen M Husbands; David J Nutt; Alan L Hudson; Emma S J Robinson
In vitro and ex vivo distribution of [3H]harmane, an endogenous beta-carboline, in rat brain.
Neuropharmacology 2006;50(3):269-76.
2006: Jon P Ruddick; Andrew K Evans; David J Nutt; Stafford L Lightman; Graham Rook; Christopher A Lowry
Tryptophan metabolism in the central nervous system: medical implications.
Expert reviews in molecular medicine 2006;8(20):1-27.
2006: David J Nutt; David S Baldwin; Anita H Clayton; Rodney Elgie; Yves Lecrubier; Angel L Montejo; George I Papakostas; Daniel Souery; Madhukar H Trivedi; Andre Tylee
Consensus statement and research needs: the role of dopamine and norepinephrine in depression and antidepressant treatment.
The Journal of clinical psychiatry 2006;67 Suppl 6():46-9.
2006: David J Nutt
The role of dopamine and norepinephrine in depression and antidepressant treatment.
The Journal of clinical psychiatry 2006;67 Suppl 6():3-8.
2006: David J Nutt
Informed consent--a new approach to drug regulation?
Journal of psychopharmacology (Oxford, England) 2006;20(1):3-4.
2005: Anita Kornicka; Franciszek Saczewski; Robin J Tyacke; Alan L Hudson; David J Nutt
Preparation, structure and affinity for imidazoline I2 receptors and alpha2-adrenoceptors of 1-[(4,5-dihydroimidazolidin-2-yl)imino]indan-2-ols.
Acta poloniae pharmaceutica 2005;62(6):497-502.
2005: Sue J Wilson; Jayne E Bailey; Ann S Rich; Jon Nash; Mariona Adrover; A Tournoux; David J Nutt
The use of sleep measures to compare a new 5HT1A agonist with buspirone in humans.
Journal of psychopharmacology (Oxford, England) 2005;19(6):609-13.
2005: Simon J C Davies; Smita A Pandit; Adrian Feeney; Brian J Stevenson; Robert W Kerwin; David J Nutt; E Jane Marshall; Stephen Boddington; Anne Lingford-Hughes
Is there cognitive impairment in clinically 'healthy' abstinent alcohol dependence?
Alcohol and alcoholism (Oxford, Oxfordshire) 2005;40(6):498-503.
2005: Neil J Anderson; Patrick A Lupo; David J Nutt; Alan L Hudson; Emma S J Robinson
Characterisation of imidazoline I2 binding sites in pig brain.
European journal of pharmacology 2005;519(1-2):68-74.
2005: Emma S J Robinson; David J Nutt; Helen C Jackson; Alan L Hudson
The uptake of a fluorescently labelled antisense oligonucleotide in vitro and in vivo.
Journal of neuroscience methods 2005;147(1):48-54.
2005: Anne Lingford-Hughes; Sue J Wilson; Adrian Feeney; P G Grasby; David J Nutt
A proof-of-concept study using [11C]flumazenil PET to demonstrate that pagoclone is a partial agonist.
Psychopharmacology 2005;180(4):789-91.
2005: Anne Lingford-Hughes; Sue J Wilson; Vincent J Cunningham; Adrian Feeney; B Stevenson; David J Brooks; David J Nutt
GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study.
Psychopharmacology 2005;180(4):595-606.
2005: Caroline J Bell; Sean Hood; David J Nutt
Acute tryptophan depletion. Part II: clinical effects and implications.
The Australian and New Zealand journal of psychiatry 2005;39(7):565-74.
2005: Sean Hood; Caroline J Bell; David J Nutt
Acute tryptophan depletion. Part I: rationale and methodology.
The Australian and New Zealand journal of psychiatry 2005;39(7):558-64.
2005: David A Slattery; John A Morrow; Alan L Hudson; David R Hill; David J Nutt; Brian Henry
Comparison of alterations in c-fos and Egr-1 (zif268) expression throughout the rat brain following acute administration of different classes of antidepressant compounds.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(7):1278-87.
2005: Sue Wilson; David J Nutt
Assessment and management of insomnia.
Clinical medicine (London, England) 2005;5(2):101-4.
2005: David J Nutt
NICE: The National Institute of Clinical Excellence -- or Eccentricity? Reflections on the Z-drugs as hypnotics.
Journal of psychopharmacology (Oxford, England) 2005;19(2):125-7.
2005: Franciszek Saczewski; Ewa Kobierska; Robin J Tyacke; Alan L Hudson; David J Nutt; Maria Gdaniec
Synthesis of 2,3,5,6-tetrahydro-3H-imidazo[2,1-b] [1,3,5]benzotriazepines and their oxidative ring contraction into 1-(4,5-dihydro-1H-imidazol-2-yl)-1H-benzimidazoles.
Farmaco (Società chimica italiana : 1989) 2005;60(2):127-34.
2005: Robin J Tyacke; Emma S J Robinson; Margaret D Lalies; Susan P Hume; Alan L Hudson; David J Nutt
Estimation of endogenous noradrenaline release in rat brain in vivo using [3H]RX 821002.
Synapse (New York, N.Y.) 2005;55(2):126-32.
2005: Jon R Nash; David J Nutt
Pharmacotherapy of anxiety.
Handbook of experimental pharmacology 2005;(169):469-501.
2005: Mark R C Daglish; Anne Lingford-Hughes; David J Nutt
Human functional neuroimaging connectivity research in dependence.
Reviews in the neurosciences 2005;16(2):151-7.
2005: Jayne E Bailey; Spilios V Argyropoulos; Adrian H Kendrick; David J Nutt
Behavioral and cardiovascular effects of 7.5% CO2 in human volunteers.
Depression and anxiety 2005;21(1):18-25.
2005: David J Nutt
Overview of diagnosis and drug treatments of anxiety disorders.
CNS spectrums 2005;10(1):49-56.
2005: Jan K Melichar; Susan P Hume; Tim M Williams; Mark R C Daglish; Lindsay G Taylor; Rabia Ahmad; Andrea L Malizia; David J Brooks; Judith S Myles; Anne Lingford-Hughes; David J Nutt
Using [11C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: clinical and preclinical studies.
The Journal of pharmacology and experimental therapeutics 2005;312(1):309-15.
2004: Christine A Parker; Neil J Anderson; Emma S J Robinson; Rhiannon Price; Robin J Tyacke; Stephen M Husbands; Michael P Dillon; Richard M Eglen; Alan L Hudson; David J Nutt; Matthew Crump; John Crosby
Harmane and harmalan are bioactive components of classical clonidine-displacing substance.
Biochemistry 2004;43(51):16385-92.
2004: Spilios V Argyropoulos; Sean Hood; Mariona Adrover; Caroline J Bell; Ann S Rich; Jon R Nash; Neil C Rich; Harry J Witchel; David J Nutt
Tryptophan depletion reverses the therapeutic effect of selective serotonin reuptake inhibitors in social anxiety disorder.
Biological psychiatry 2004;56(7):503-9.
2004: Sue J Wilson; Jayne E Bailey; Ann S Rich; Mariona Adrover; John P Potokar; David J Nutt
Using sleep to evaluate comparative serotonergic effects of paroxetine and citalopram.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2004;14(5):367-72.
2004: Anne Lingford-Hughes; S Welch; David J Nutt
Evidence-based guidelines for the pharmacological management of substance misuse, addiction and comorbidity: recommendations from the British Association for Psychopharmacology.
Journal of psychopharmacology (Oxford, England) 2004;18(3):293-335.
2004: Susan G Walling; David J Nutt; Margaret D Lalies; Carolyn W Harley
Orexin-A infusion in the locus ceruleus triggers norepinephrine (NE) release and NE-induced long-term potentiation in the dentate gyrus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(34):7421-6.
2004: David J Nutt; Anne Lingford-Hughes
Infecting the brain to stop addiction?
Proceedings of the National Academy of Sciences of the United States of America 2004;101(31):11193-4.
2004: Emma S J Robinson; Robin J Tyacke; Louise Finch; Graham Willmott; Stephen M Husbands; David J Nutt; Alan L Hudson
Pharmacological characterisation of novel alpha 2-adrenoceptor antagonists as potential brain imaging agents.
Neuropharmacology 2004;46(6):847-55.
2004: Simon J C Davies; Peter R Jackson; John P Potokar; David J Nutt
Treatment of anxiety and depressive disorders in patients with cardiovascular disease.
BMJ (Clinical research ed.) 2004;328(7445):939-43.
2004: David P Finn; Alan L Hudson; Hiroshi Kinoshita; Toni L Coventry; David S Jessop; David J Nutt; Michael S Harbuz
Imidazoline2 (I2) receptor- and alpha2-adrenoceptor-mediated modulation of hypothalamic-pituitary-adrenal axis activity in control and acute restraint stressed rats.
Journal of psychopharmacology (Oxford, England) 2004;18(1):47-53.
2004: Sue J Wilson; Ann S Rich; N C Rich; John P Potokar; David J Nutt
Evaluation of actigraphy and automated telephoned questionnaires to assess hypnotic effects in insomnia.
International clinical psychopharmacology 2004;19(2):77-84.
2004: David A Slattery; Alan L Hudson; David J Nutt
Invited review: the evolution of antidepressant mechanisms.
Fundamental & clinical pharmacology 2004;18(1):1-21.
2004: David J Nutt; Andrea L Malizia
Structural and functional brain changes in posttraumatic stress disorder.
The Journal of clinical psychiatry 2004;65 Suppl 1():11-7.
2003: Louise M Paterson; Emma S J Robinson; David J Nutt; Alan L Hudson
In vivo estimation of imidazoline(2) binding site turnover.
Annals of the New York Academy of Sciences 2003;1009():367-70.
2003: A Kimura; Robin J Tyacke; M C W Minchin; David J Nutt; Alan L Hudson
Identification of an I(2) binding protein from rabbit brain.
Annals of the New York Academy of Sciences 2003;1009():364-6.
2003: Robin J Tyacke; Alice Lau; Brian Grella; Richard A Glennon; David J Nutt; Alan L Hudson
Investigation of the affinities of two new beta-carbolines for rat brain imidazoline(2) receptors.
Annals of the New York Academy of Sciences 2003;1009():361-3.
2003: Robin J Tyacke; F Sazczewski; Piotr Tabin; J Sazczewski; David J Nutt; Alan L Hudson
Initial evaluation of novel selective ligands for imidazoline(2) receptors in rat whole brain.
Annals of the New York Academy of Sciences 2003;1009():357-60.
2003: Louise M Paterson; Robin J Tyacke; David J Nutt; Alan L Hudson
Relationship between imidazoline(2) sites and monoamine oxidase.
Annals of the New York Academy of Sciences 2003;1009():353-6.
2003: Alan L Hudson; Robin J Tyacke; Margaret D Lalies; N Davies; David P Finn; Octavi Marti; E Robinson; Stephen M Husbands; M C W Minchin; A Kimura; David J Nutt
Novel ligands for the investigation of imidazoline receptors and their binding proteins.
Annals of the New York Academy of Sciences 2003;1009():302-8.
2003: Emma S J Robinson; R E Price; David J Nutt; Alan L Hudson
BU98008, a highly selective imidazoline(1)-receptor ligand.
Annals of the New York Academy of Sciences 2003;1009():283-7.
2003: Neil J Anderson; Emma S J Robinson; Stephen M Husbands; P Delagrange; David J Nutt; Alan L Hudson
Characterization of [(3)H]harmane binding to rat whole brain membranes.
Annals of the New York Academy of Sciences 2003;1009():175-9.
2003: Emma S J Robinson; Neil J Anderson; John Crosby; David J Nutt; Alan L Hudson
Endogenous beta-carbolines as clonidine-displacing substances.
Annals of the New York Academy of Sciences 2003;1009():157-66.
2003: David J Nutt
Death and dependence: current controversies over the selective serotonin reuptake inhibitors.
Journal of psychopharmacology (Oxford, England) 2003;17(4):355-64.
2003: Mark R C Daglish; Aviv Weinstein; Andrea L Malizia; Susan Wilson; Jan K Melichar; Anne Lingford-Hughes; Judith S Myles; Paul M Grasby; David J Nutt
Functional connectivity analysis of the neural circuits of opiate craving: "more" rather than "different"?
NeuroImage 2003;20(4):1964-70.
2003: Mark R C Daglish; David J Nutt
Brain imaging studies in human addicts.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(6):453-8.
2003: Jon R Nash; Sue J Wilson; John P Potokar; David J Nutt
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
Neurology 2003;61(8):1161; author reply 1161.
2003: Franciszek Saczewski; Alan L Hudson; Robin J Tyacke; David J Nutt; J Man; Piotr Tabin; Jaroslaw Saczewski
2-(4,5-dihydro-1H-imidazol-2-yl)indazole (indazim) derivatives as selective I(2) imidazoline receptor ligands.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;20(2):201-8.
2003: Spilios V Argyropoulos; Jane A Hicks; Jon R Nash; Caroline J Bell; Ann S Rich; David J Nutt; Sue J Wilson
Correlation of subjective and objective sleep measurements at different stages of the treatment of depression.
Psychiatry research 2003;120(2):179-90.
2003: Andrew Smith; Carolyn Brice; Jon Nash; Neil Rich; David J Nutt
Caffeine and central noradrenaline: effects on mood, cognitive performance, eye movements and cardiovascular function.
Journal of psychopharmacology (Oxford, England) 2003;17(3):283-92.
2003: Jayne E Bailey; Spilios V Argyropoulos; Stafford L Lightman; David J Nutt
Does the brain noradrenaline network mediate the effects of the CO2 challenge?
Journal of psychopharmacology (Oxford, England) 2003;17(3):252-9.
2003: Aviv Weinstein; Barbara Feldtkeller; Adrian Feeney; Anne Lingford-Hughes; David J Nutt
A pilot study on the effects of treatment with acamprosate on craving for alcohol in alcohol-dependent patients.
Addiction biology 2003;8(2):229-32.
2003: Nicholas J Coupland; Sue J Wilson; John P Potokar; Caroline Bell; David J Nutt
Increased sympathetic response to standing in panic disorder.
Psychiatry research 2003;118(1):69-79.
2003: David P Finn; Octavi Marti; Michael S Harbuz; Astrid Vallès; Xavier Belda; Cristina Márquez; David S Jessop; Margaret D Lalies; Antonio Armario; David J Nutt; Alan L Hudson
Behavioral, neuroendocrine and neurochemical effects of the imidazoline I2 receptor selective ligand BU224 in naive rats and rats exposed to the stress of the forced swim test.
Psychopharmacology 2003;167(2):195-202.
2003: Jan K Melichar; Judith S Myles; C B Eap; David J Nutt
Using saccadic eye movements as objective measures of tolerance in methadone dependent individuals during the hydromorphone challenge test.
Addiction biology 2003;8(1):59-66.
2003: Caroline Bell; Sue Wilson; Ann Rich; Jayne Bailey; David J Nutt
Effects on sleep architecture of pindolol, paroxetine and their combination in healthy volunteers.
Psychopharmacology 2003;166(2):102-10.
2003: Fergus D Law; David J Nutt
Maintenance buprenorphine for opioid users.
Lancet 2003;361(9358):634-5.
2003: Harry J Witchel; Jules C Hancox; David J Nutt
Psychotropic drugs, cardiac arrhythmia, and sudden death.
Journal of clinical psychopharmacology 2003;23(1):58-77.
2003: Jan K Melichar; David J Nutt; Andrea L Malizia
Naloxone displacement at opioid receptor sites measured in vivo in the human brain.
European journal of pharmacology 2003;459(2-3):217-9.
2003: David J Nutt; Anne Lingford-Hughes; Mark R C Daglish
Future directions in substance dependence research.
Journal of neural transmission. Supplementum 2003;(64):95-103.
2003: Anne Lingford-Hughes; Simon J C Davies; S McIver; Tim M Williams; Mark R C Daglish; David J Nutt
Addiction.
British medical bulletin 2003;65():209-22.
2002: Sue J Wilson; Jayne E Bailey; C Alford; Aviv Weinstein; David J Nutt
Effects of 5 weeks of administration of fluoxetine and dothiepin in normal volunteers on sleep, daytime sedation, psychomotor performance and mood.
Journal of psychopharmacology (Oxford, England) 2002;16(4):321-31.
2002: David J Nutt; James C Ballenger; David Sheehan; Hans-Ulrich Wittchen
Generalized anxiety disorder: comorbidity, comparative biology and treatment.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2002;5(4):315-25.
2002: Julia Hardy; Spilios V Argyropoulos; David J Nutt
Venlafaxine: a new class of antidepressant.
Hospital medicine (London, England : 1998) 2002;63(9):549-52.
2002: Caroline Bell; Hilde Vanderlinden; Reinhard Hiersemenzel; Christian Otoul; David J Nutt; Sue Wilson
The effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy.
Journal of sleep research 2002;11(3):255-63.
2002: Emma S J Robinson; Robin J Tyacke; David J Nutt; Alan L Hudson
Distribution of [(3)H]BU224, a selective imidazoline I(2) binding site ligand, in rat brain.
European journal of pharmacology 2002;450(1):55-60.
2002: Spilios V Argyropoulos; Jayne E Bailey; Sean Hood; Adrian H Kendrick; Ann S Rich; Gabriel Laszlo; Jon R Nash; Stafford L Lightman; David J Nutt
Inhalation of 35% CO(2) results in activation of the HPA axis in healthy volunteers.
Psychoneuroendocrinology 2002;27(6):715-29.
2002: Robin J Tyacke; Emma S J Robinson; David J Nutt; Alan L Hudson
5-Isothiocyanato-2-benzofuranyl-2-imidazoline (BU99006) an irreversible imidazoline(2) binding site ligand: in vitro and in vivo characterisation in rat brain.
Neuropharmacology 2002;43(1):75-83.
2002: Anne Lingford-Hughes; Susan P Hume; Adrian Feeney; Ella Hirani; Safiye Osman; Vincent J Cunningham; Victor W Pike; David J Brooks; David J Nutt
Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(7):878-89.
2002: David J Nutt
Tolerability and safety aspects of mirtazapine.
Human psychopharmacology 2002;17 Suppl 1():S37-41.
2002: David J Nutt
The neuropharmacology of serotonin and noradrenaline in depression.
International clinical psychopharmacology 2002;17 Suppl 1():S1-12.
2002: David P Finn; Margaret D Lalies; Michael S Harbuz; David S Jessop; Alan L Hudson; David J Nutt
Imidazoline(2) (I(2)) binding site- and alpha(2)-adrenoceptor-mediated modulation of central noradrenergic and HPA axis function in control rats and chronically stressed rats with adjuvant-induced arthritis.
Neuropharmacology 2002;42(7):958-65.
2002: J A Hicks; Spilios V Argyropoulos; Ann S Rich; Jon R Nash; Caroline J Bell; C Edwards; David J Nutt; Sue J Wilson
Randomised controlled study of sleep after nefazodone or paroxetine treatment in out-patients with depression.
The British journal of psychiatry : the journal of mental science 2002;180():528-35.
2002: Robin J Tyacke; Emma S J Robinson; Rebecca Schnabel; John W Lewis; Stephen M Husbands; David J Nutt; Alan L Hudson
N1'-fluoroethyl-naltrindole (BU97001) and N1'-fluoroethyl-(14-formylamino)-naltrindole (BU97018) potential delta-opioid receptor PET ligands.
Nuclear medicine and biology 2002;29(4):455-62.
2002: Caroline Bell; Sam Forshall; Mariona Adrover; Jon Nash; Sean Hood; Spilios V Argyropoulos; Ann Rich; David J Nutt
Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine.
Journal of psychopharmacology (Oxford, England) 2002;16(1):5-14.
2001: Harriet Crofts; Sue Wilson; Neil Muggleton; David J Nutt; E A M Scott; Peter C Pearce
Investigation of the sleep electrocorticogram of the common marmoset (Callithrix jacchus) using radiotelemetry.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2001;112(12):2265-73.
2001: Spilios V Argyropoulos; Caroline J Bell; David J Nutt
Brain function in social anxiety disorder.
The Psychiatric clinics of North America 2001;24(4):707-22.
2001: David J Nutt; Andrea L Malizia
New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder.
The British journal of psychiatry : the journal of mental science 2001;179():390-6.
2001: Mark R C Daglish; Aviv Weinstein; Andrea L Malizia; Sue Wilson; Jan K Melichar; S Britten; C Brewer; Anne Lingford-Hughes; Judith S Myles; Paul M Grasby; David J Nutt
Changes in regional cerebral blood flow elicited by craving memories in abstinent opiate-dependent subjects.
The American journal of psychiatry 2001;158(10):1680-6.
2001: Stephen M Husbands; R A Glennon; S Gorgerat; R Gough; Robin J Tyacke; John Crosby; David J Nutt; John W Lewis; Alan L Hudson
beta-carboline binding to imidazoline receptors.
Drug and alcohol dependence 2001;64(2):203-8.
2001: JJ Sandford; Sam Forshall; Caroline Bell; Spilios V Argyropoulos; Ann Rich; K J D'Orlando; R E Gammans; David J Nutt
Crossover trial of pagoclone and placebo in patients with DSM-IV panic disorder.
Journal of psychopharmacology (Oxford, England) 2001;15(3):205-8.
2001: Barbara Feldtkeller; Aviv Weinstein; W M Cox; David J Nutt
Effects of contextual priming on reactions to craving and withdrawal stimuli in alcohol-dependent participants.
Experimental and clinical psychopharmacology 2001;9(3):343-51.
2001: C Bell; J Abrams; David J Nutt
Tryptophan depletion and its implications for psychiatry.
The British journal of psychiatry : the journal of mental science 2001;178():399-405.
2001: J Clayson; Andrew R Jales; Robin J Tyacke; Alan L Hudson; David J Nutt; John W Lewis; Stephen M Husbands
Selective delta-opioid receptor ligands: potential PET ligands based on naltrindole.
Bioorganic & medicinal chemistry letters 2001;11(7):939-43.
2001: Jan K Melichar; A Haida; C Rhodes; Alan Reynolds; David J Nutt; Andrea L Malizia
Venlafaxine occupation at the noradrenaline reuptake site: in-vivo determination in healthy volunteers.
Journal of psychopharmacology (Oxford, England) 2001;15(1):9-12.
2001: Jan K Melichar; Mark R C Daglish; David J Nutt
Addiction and withdrawal--current views.
Current opinion in pharmacology 2001;1(1):84-90.
2001: David J Nutt
Neurobiological mechanisms in generalized anxiety disorder.
The Journal of clinical psychiatry 2001;62 Suppl 11():22-7; discussion 28.
2000: Spilios V Argyropoulos; JJ Sandford; David J Nutt
The psychobiology of anxiolytic drug. Part 2: Pharmacological treatments of anxiety.
Pharmacology & therapeutics 2000;88(3):213-27.
2000: JJ Sandford; Spilios V Argyropoulos; David J Nutt
The psychobiology of anxiolytic drugs. Part 1: Basic neurobiology.
Pharmacology & therapeutics 2000;88(3):197-212.
2000: David J Nutt
Treatment of depression and concomitant anxiety.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2000;10 Suppl 4():S433-7.
2000: A M Weinstein; Barbara Feldtkeller; Fergus D Law; Judith S Myles; David J Nutt
The processing of automatic thoughts of drug use and craving in opiate-dependent individuals.
Experimental and clinical psychopharmacology 2000;8(4):549-53.
2000: Jonathan Evans; Barney Reeves; H Platt; A Leibenau; David Goldman; Kieran Jefferson; David J Nutt
Impulsiveness, serotonin genes and repetition of deliberate self-harm (DSH).
Psychological medicine 2000;30(6):1327-34.
2000: Sue J Wilson; Caroline Bell; Nicholas J Coupland; David J Nutt
Sleep changes during long-term treatment of depression with fluvoxamine--a home-based study.
Psychopharmacology 2000;149(4):360-5.
2000: Susan P Hume; Ella Hirani; Jolanta Opacka-Juffry; Safiye Osman; R Myers; Roger Gunn; Julie A McCarron; R D Clark; Jan K Melichar; David J Nutt; Victor W Pike
Evaluation of [O-methyl-11C]RS-15385-197 as a positron emission tomography radioligand for central alpha2-adrenoceptors.
European journal of nuclear medicine 2000;27(5):475-84.
2000: Emma S J Robinson; David J Nutt; Helen C Jackson; Alan L Hudson
Behavioural and physiological effects induced by an infusion of antisense to alpha(2D)-adrenoceptors in the rat.
British journal of pharmacology 2000;130(1):153-9.
2000: Jonathan Evans; H Platts; Stafford Lightman; David J Nutt
Impulsiveness and the prolactin response to d-fenfluramine.
Psychopharmacology 2000;149(2):147-52.
2000: P A Coates; Peter Grundt; Emma S J Robinson; David J Nutt; Robin J Tyacke; Alan L Hudson; John W Lewis; Stephen M Husbands
Probes for imidazoline binding sites: synthesis and evaluation of a selective, irreversible I2 ligand.
Bioorganic & medicinal chemistry letters 2000;10(6):605-7.
2000: Andrea L Malizia; Jan K Melichar; C G Rhodes; A Haida; Alan Reynolds; T Jones; David J Nutt
Desipramine binding to noradrenaline reuptake sites in cardiac sympathetic neurons in man in vivo.
European journal of pharmacology 2000;391(3):263-7.
2000: John P Potokar; David J Nutt
Chest pain: panic attack or heart attack?
International journal of clinical practice 2000;54(2):110-4.
2000: Christine A Parker; Alan L Hudson; David J Nutt; Michael P Dillon; Richard M Eglen; John Crosby
Isolation of RP-HPLC pure clonidine-displacing substance from NG108-15 cells.
European journal of pharmacology 2000;387(1):27-30.
2000: Sue J Wilson; Jayne E Bailey; C Alford; David J Nutt
Sleep and daytime sleepiness the next day following single night-time dose of fluvoxamine, dothiepin and placebo in normal volunteers.
Journal of psychopharmacology (Oxford, England) 2000;14(4):378-86.
2000: David J Nutt
The psychobiology of posttraumatic stress disorder.
The Journal of clinical psychiatry 2000;61 Suppl 5():24-9; discussion 30-2.
2000: Nicholas J Coupland; Caroline Bell; John P Potokar; E Dorkins; David J Nutt
Flumazenil challenge in social phobia.
Depression and anxiety 2000;11(1):27-30.
1999: John P Potokar; C Lawson; S Wilson; David J Nutt
Behavioral, neuroendocrine, and cardiovascular response to flumazenil: no evidence for an altered benzodiazepine receptor sensitivity in panic disorder.
Biological psychiatry 1999;46(12):1709-11.
1999: Alan L Hudson; Emma S J Robinson; Margaret D Lalies; Robin J Tyacke; Helen C Jackson; David J Nutt
In vitro and in vivo approaches to the characterization of the alpha2-adrenoceptor.
Journal of autonomic pharmacology 1999;19(6):311-20.
1999: Spilios V Argyropoulos; David J Nutt
The use of benzodiazepines in anxiety and other disorders.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1999;9 Suppl 6():S407-12.
1999: Emma S J Robinson; David J Nutt; L Hall; Helen C Jackson; Alan L Hudson
Autoradiographical and behavioural effects of a chronic infusion of antisense to the alpha2D-adrenoceptor in the rat.
British journal of pharmacology 1999;128(3):515-22.
1999: John P Potokar; Nicholas J Coupland; Sue Wilson; Ann Rich; David J Nutt
Assessment of GABA(A)benzodiazepine receptor (GBzR) sensitivity in patients on benzodiazepines.
Psychopharmacology 1999;146(2):180-4.
1999: Christine A Parker; Alan L Hudson; David J Nutt; Michael P Dillon; Richard M Eglen; S L Chan; Noel G Morgan; John Crosby
Extraction of active clonidine-displacing substance from bovine lung and comparison with clonidine-displacing substance extracted from other tissues.
European journal of pharmacology 1999;378(2):213-21.
1999: Harriet Crofts; Neil Muggleton; Andrew P Bowditch; Peter C Pearce; David J Nutt; E A M Scott
Home cage presentation of complex discrimination tasks to marmosets and rhesus monkeys.
Laboratory animals 1999;33(3):207-14.
1999: David J Nutt; Sam Forshall; Caroline Bell; Ann Rich; JJ Sandford; Jon Nash; Spilios V Argyropoulos
Mechanisms of action of selective serotonin reuptake inhibitors in the treatment of psychiatric disorders.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1999;9 Suppl 3():S81-6.
1999: Alan L Hudson; S Luscombe; R E Gouch; David J Nutt; Robin J Tyacke
Endogenous indoleamines demonstrate moderate affinity for I2 binding sites.
Annals of the New York Academy of Sciences 1999;881():212-6.
1999: Robin J Tyacke; David J Nutt; Alan L Hudson
Autoradiography of I2 receptors in frog brain.
Annals of the New York Academy of Sciences 1999;881():208-11.
1999: Margaret D Lalies; A Hibell; Alan L Hudson; David J Nutt
Inhibition of central monoamine oxidase by imidazoline2 site-selective ligands.
Annals of the New York Academy of Sciences 1999;881():114-7.
1999: Christine A Parker; Alan L Hudson; David J Nutt; Michael P Dillon; Richard M Eglen; John Crosby
Comparison of crude methanolic CDS extracts from various tissues.
Annals of the New York Academy of Sciences 1999;881():92-6.
1999: Alan L Hudson; R Gough; Robin J Tyacke; LA Lione; Margaret D Lalies; J Lewis; Stephen M Husbands; P Knight; Fraser Murray; Peter H Hutson; David J Nutt
Novel selective compounds for the investigation of imidazoline receptors.
Annals of the New York Academy of Sciences 1999;881():81-91.
1999: Caroline Bell; David J Nutt
Paroxetine and its uses in psychiatry.
Hospital medicine (London, England : 1998) 1999;60(5):353-6.
1999: David J Nutt; Sue Wilson
Evaluation of severe insomnia in the general population--implications for the management of insomnia: the UK perspective.
Journal of psychopharmacology (Oxford, England) 1999;13(4 Suppl 1):S33-4.
1999: Andrew Smith; W Sturgess; N Rich; Carolyn Brice; C Collison; J Bailey; Sue Wilson; David J Nutt
The effects of idazoxan on reaction times, eye movements and the mood of healthy volunteers and patients with upper respiratory tract illnesses.
Journal of psychopharmacology (Oxford, England) 1999;13(2):148-51.
1999: David J Nutt
Care of depressed patients with anxiety symptoms.
The Journal of clinical psychiatry 1999;60 Suppl 17():23-7; discussion 46-8.
1999: Caroline J Bell; Andrea L Malizia; David J Nutt
The neurobiology of social phobia.
European archives of psychiatry and clinical neuroscience 1999;249 Suppl 1():S11-8.
1998: David J Nutt
Substance-P antagonists: a new treatment for depression?
Lancet 1998;352(9141):1644-6.
1998: J W Dalley; Christine A Parker; E Wülfert; Alan L Hudson; David J Nutt
Potentiation of barbiturate-induced alterations in presynaptic noradrenergic function in rat frontal cortex by imidazol(in)e alpha2-adrenoceptor agonists.
British journal of pharmacology 1998;125(3):441-6.
1998: Richard M Eglen; Alan L Hudson; D A Kendall; David J Nutt; Noel G Morgan; V G Wilson; Michael P Dillon
'Seeing through a glass darkly': casting light on imidazoline 'I' sites.
Trends in pharmacological sciences 1998;19(9):381-90.
1998: Andrea L Malizia; Vincent J Cunningham; Caroline J Bell; Peter F Liddle; T Jones; David J Nutt
Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study.
Archives of general psychiatry 1998;55(8):715-20.
1998: LA Lione; David J Nutt; Alan L Hudson
Characterisation and localisation of [3H]2-(2-benzofuranyl)-2-imidazoline binding in rat brain: a selective ligand for imidazoline I2 receptors.
European journal of pharmacology 1998;353(1):123-35.
1998: Caroline J Bell; David J Nutt
Serotonin and panic.
The British journal of psychiatry : the journal of mental science 1998;172():465-71.
1998: D N Thomas; David J Nutt; R B Holman
Sertraline, a selective serotonin reuptake inhibitor modulates extracellular noradrenaline in the rat frontal cortex.
Journal of psychopharmacology (Oxford, England) 1998;12(4):366-70.
1998: David J Nutt; Caroline J Bell; Andrea L Malizia
Brain mechanisms of social anxiety disorder.
The Journal of clinical psychiatry 1998;59 Suppl 17():4-11.
1998: David J Nutt
Antidepressants in panic disorder: clinical and preclinical mechanisms.
The Journal of clinical psychiatry 1998;59 Suppl 8():24-8; discussion 29.
1998: David J Nutt
Efficacy of mirtazapine in clinically relevant subgroups of depressed patients.
Depression and anxiety 1998;7 Suppl 1():7-10.
1998: Caroline Bell; Sue Wilson; David J Nutt
Pindolol augmentation of sertraline in resistant depression and its effect on sleep.
Journal of psychopharmacology (Oxford, England) 1998;12(1):105-7.
1998: Aviv Weinstein; Barbara Feldtkeller; Andrea L Malizia; Sue Wilson; J Bailey; David J Nutt
Integrating the cognitive and physiological aspects of craving.
Journal of psychopharmacology (Oxford, England) 1998;12(1):31-8.
1997: Spilios V Argyropoulos; David J Nutt
Anhedonia and chronic mild stress model in depression.
Psychopharmacology 1997;134(4):333-6; discussion 371-7.
1997: Aviv Weinstein; Sue Wilson; J Bailey; Judith S Myles; David J Nutt
Imagery of craving in opiate addicts undergoing detoxification.
Drug and alcohol dependence 1997;48(1):25-31.
1997: John P Potokar; Nicholas J Coupland; P Glue; S Groves; Andrea L Malizia; J Bailey; S Wilson; David J Nutt
Flumazenil in alcohol withdrawal: a double-blind placebo-controlled study.
Alcohol and alcoholism (Oxford, Oxfordshire) 1997;32(5):605-11.
1997: S J Wilson; A R Lillywhite; John P Potokar; C J Bell; David J Nutt
Adult night terrors and paroxetine.
Lancet 1997;350(9072):185.
1997: Nicholas J Coupland; A Lillywhite; C E Bell; John P Potokar; David J Nutt
A pilot controlled study of the effects of flumazenil in posttraumatic stress disorder.
Biological psychiatry 1997;41(9):988-90.
1997: Nicholas J Coupland; Jayne E Bailey; John P Potokar; David J Nutt
5-HT3 receptors, nausea, and serotonin reuptake inhibition.
Journal of clinical psychopharmacology 1997;17(2):142-3.
1997: Jonathan Evans; S Battersby; Alan D Ogilvie; C A Smith; Anthony J Harmar; David J Nutt; Guy M Goodwin
Association of short alleles of a VNTR of the serotonin transporter gene with anxiety symptoms in patients presenting after deliberate self harm.
Neuropharmacology 1997;36(4-5):439-43.
1997: David J Nutt
Noradrenaline in depression: half a century of progress.
Journal of psychopharmacology (Oxford, England) 1997;11(4 Suppl):S3.
1997: Andrea L Malizia; J M Melichar; D J Brown; Roger Gunn; Alan Reynolds; Terry Jones; David J Nutt
Demonstration of clomipramine and venlafaxine occupation at serotonin reuptake sites in man in vivo.
Journal of psychopharmacology (Oxford, England) 1997;11(3):279-81.
1997: Emma S J Robinson; David J Nutt; Helen C Jackson; Alan L Hudson
Antisense oligonucleotides in psychopharmacology and behaviour: promises and pitfalls.
Journal of psychopharmacology (Oxford, England) 1997;11(3):259-69.
1997: David J Nutt
Mirtazapine: pharmacology in relation to adverse effects.
Acta psychiatrica Scandinavica. Supplementum 1997;391():31-7.
1997: David J Nutt
Management of patients with depression associated with anxiety symptoms.
The Journal of clinical psychiatry 1997;58 Suppl 8():11-6.
1997: David J Nutt; Margaret D Lalies; LA Lione; Alan L Hudson
Noradrenergic mechanisms in the prefrontal cortex.
Journal of psychopharmacology (Oxford, England) 1997;11(2):163-8.
1997: Alan L Hudson; C B Chapleo; J W Lewis; Stephen M Husbands; K Grivas; N J Mallard; David J Nutt
Identification of ligands selective for central I2-imidazoline binding sites.
Neurochemistry international 1997;30(1):47-53.
1997: Nicholas J Coupland; S Wilson; David J Nutt
Antidepressant drugs and the cardiovascular system: a comparison of tricylics and selective serotonin reuptake inhibitors and their relevance for the treatment of psychiatric patients with cardiovascular problems.
Journal of psychopharmacology (Oxford, England) 1997;11(1):83-92.
1996: Susan P Hume; S Ashworth; A A Lammertsma; Jolanta Opacka-Juffry; M P Law; Julie A McCarron; R D Clark; David J Nutt; Victor W Pike
Evaluation in rat of RS-79948-197 as a potential PET ligand for central alpha 2-adrenoceptors.
European journal of pharmacology 1996;317(1):67-73.
1996: David J Nutt; S A Montgomery
Moclobemide in the treatment of social phobia.
International clinical psychopharmacology 1996;11 Suppl 3():77-82.
1996: J Altman; Barry J Everitt; S Glautier; Athina Markou; David J Nutt; R Oretti; Gavin D Phillips; Trevor W Robbins
The biological, social and clinical bases of drug addiction: commentary and debate.
Psychopharmacology 1996;125(4):285-345.
1996: LA Lione; David J Nutt; Alan L Hudson
[3H]2-(2-benzofuranyl)-2-imidazoline: a new selective high affinity radioligand for the study of rabbit brain imidazoline I2 receptors.
European journal of pharmacology 1996;304(1-3):221-9.
1996: Nicholas J Coupland; Andrea L Malizia; J Bailey; David J Nutt
Thyrotropin-releasing hormone: a potential comparator for the panicogenic effects of pentagastrin and CCK?
Biological psychiatry 1996;39(6):465-6.
1996: S Tolchard; A S Hare; David J Nutt; G Clarke
TNF alpha mimics the endocrine but not the thermoregulatory responses of bacterial lipopolysaccharide (LPS): correlation with FOS-expression in the brain.
Neuropharmacology 1996;35(3):243-8.
1996: David J Nutt
Addiction: brain mechanisms and their treatment implications.
Lancet 1996;347(8993):31-6.
1996: Aviv Weinstein; Sue Wilson; J Bailey; David J Nutt
Sedative antidepressants impair visual detection mechanisms in humans.
Journal of psychopharmacology (Oxford, England) 1996;10(2):141-5.
1996: David J Nutt
Editorial.
Journal of psychopharmacology (Oxford, England) 1996;10(1):1.
1996: A M Weinstein; L Neal; A Lillywhite; John P Potokar; David J Nutt
Cognitive processing in post-traumatic stress disorder.
Anxiety 1996;2(3):130-9.
1996: Andrea L Malizia; Roger Gunn; S J Wilson; S H Waters; P M Bloomfield; Vincent J Cunningham; David J Nutt
Benzodiazepine site pharmacokinetic/pharmacodynamic quantification in man: direct measurement of drug occupancy and effects on the human brain in vivo.
Neuropharmacology 1996;35(9-10):1483-91.
1995: Nicholas J Coupland; S J Wilson; John P Potokar; C E Bell; J E Bailey; David J Nutt
A comparison of the effects of phenelzine treatment with moclobemide treatment on cardiovascular reflexes.
International clinical psychopharmacology 1995;10(4):229-38.
1995: Nicholas J Coupland; J E Bailey; P Glue; David J Nutt
The cardiovascular and subjective effects of thyrotropin releasing hormone (TRH) and a stable analogue, dimethyl proline-TRH, in healthy volunteers.
British journal of clinical pharmacology 1995;40(3):223-9.
1995: David J Nutt; N French; S Handley; A Hudson; Stephen M Husbands; H Jackson; Shaun Jordan; Margaret D Lalies; J Lewis; LA Lione
Functional studies of specific imidazoline-2 receptor ligands.
Annals of the New York Academy of Sciences 1995;763():125-39.
1995: Andrea L Malizia; David J Nutt
The effects of flumazenil in neuropsychiatric disorders.
Clinical neuropharmacology 1995;18(3):215-32.
1995: N French; Margaret D Lalies; David J Nutt; Judith A Pratt
Idazoxan-induced reductions in cortical glucose use are accompanied by an increase in noradrenaline release: complementary [14C]2-deoxyglucose and microdialysis studies.
Neuropharmacology 1995;34(6):605-13.
1995: Nicholas J Coupland; J E Bailey; S J Wilson; R Horvath; David J Nutt
The effects of clonidine on cardiovascular responses to standing in healthy volunteers.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society 1995;5(3):171-7.
1995: Jayne E Bailey; Nicholas J Coupland; John P Potokar; David J Nutt
The 5-HT3 antagonist ondansetron reduces gastrointestinal side effects induced by a specific serotonin re-uptake inhibitor in man.
Journal of psychopharmacology (Oxford, England) 1995;9(2):137-41.
1995: A M Weinstein; David J Nutt
A cognitive dysfunction in anxiety and its amelioration by effective treatment with SSRIs.
Journal of psychopharmacology (Oxford, England) 1995;9(2):83-9.
1995: Andrea L Malizia; Jan K Melichar; David J Nutt; K Poole; C Rhodes; L Schnorr; D Bateman; D Brown; D Fahy; G Forse; R Gunn; A Haida; T Jones
A new human (psycho)pharmacology tool: the multiple organs coincidences counter (MOCC).
Journal of psychopharmacology (Oxford, England) 1995;9(4):294-306.
1995: David J Nutt
Venlafaxine: the yin and yang of antidepressants?
Journal of psychopharmacology (Oxford, England) 1995;9(3):205-6.
1995: David J Nutt
The anxiety factor in depression.
Journal of psychopharmacology (Oxford, England) 1995;9(2 Suppl):185-9.
1995: Andrea L Malizia; Nicholas J Coupland; David J Nutt
Benzodiazepine receptor function in anxiety disorders.
Advances in biochemical psychopharmacology 1995;48():115-33.
1995: David J Nutt; S J Wilson; Nicholas J Coupland
Use of selective serotonin reuptake inhibitors and other serotonergic drugs in the biological dissection of affective disorders.
International clinical psychopharmacology 1995;9 Suppl 4():53-9.
1994: Nicholas J Coupland; J E Bailey; S J Wilson; W Z Potter; David J Nutt
A pharmacodynamic study of the alpha 2-adrenergic receptor antagonist ethoxyidazoxan in healthy volunteers.
Clinical pharmacology and therapeutics 1994;56(4):420-9.
1994: D N Thomas; David J Nutt; R B Holman
Regionally specific changes in extracellular noradrenaline following chronic idazoxan as revealed by in vivo microdialysis.
European journal of pharmacology 1994;261(1-2):53-7.
1994: A R Lillywhite; S J Wilson; David J Nutt
Successful treatment of night terrors and somnambulism with paroxetine.
The British journal of psychiatry : the journal of mental science 1994;164(4):551-4.
1994: David J Nutt
Putting the 'A' in atypical: does α2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics?
Journal of psychopharmacology (Oxford, England) 1994;8(4):193-5.
1994: David J Nutt; T J Peters
Alcohol: the drug.
British medical bulletin 1994;50(1):5-17.
1993: H C Jackson; I J Griffin; David J Nutt
Buprenorphine-cocaine interactions in mice: effect on locomotor activity and hole-dipping behaviour.
The Journal of pharmacy and pharmacology 1993;45(7):636-40.
1993: Victor W Pike; Christer Halldin; C Crouzel; L Barré; David J Nutt; Safiye Osman; F Shah; D R Turton; S L Waters
Radioligands for PET studies of central benzodiazepine receptors and PK (peripheral benzodiazepine) binding sites--current status.
Nuclear medicine and biology 1993;20(4):503-25.
1993: David J Nutt
The approach to new anxiolytics.
The Journal of pharmacy and pharmacology 1993;45 Suppl 1():352-4.
1993: David J Nutt; J F Deakin; T J Crow
The psychopharmacology of social communication and its disorders: November 1992, London.
Journal of psychopharmacology (Oxford, England) 1993;7(2):226-9.
1993: David J Nutt
Monoamine oxidase inhibitors: in from the cold?
Journal of psychopharmacology (Oxford, England) 1993;7(1 Suppl):97-9.
1993: H C Jackson; David J Nutt
Investigation of the involvement of opioid receptors in the action of anticonvulsants.
Psychopharmacology 1993;111(4):486-90.
1993: David J Nutt; P Glue; Sue Wilson; S Groves; Nicholas J Coupland; J Bailey
Flumazenil in alcohol withdrawal.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1993;2():337-41.
1993: S J Wilson; P Glue; D Ball; David J Nutt
Saccadic eye movement parameters in normal subjects.
Electroencephalography and clinical neurophysiology 1993;86(1):69-74.
1992: H C Jackson; David J Nutt
Are 5-HT receptors or beta-adrenoceptors involved in idazoxan-induced food and water intake?
Neuropharmacology 1992;31(11):1081-7.
1992: Susan P Hume; A A Lammertsma; Jolanta Opacka-Juffry; R G Ahier; R Myers; J E Cremer; A L Hudson; David J Nutt; Victor W Pike
Quantification of in vivo binding of [3H]RX 821002 in rat brain: evaluation as a radioligand for central alpha 2-adrenoceptors.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(8):841-9.
1992: H C Jackson; David J Nutt
Effects of benzodiazepine receptor inverse agonists on locomotor activity and exploration in mice.
European journal of pharmacology 1992;221(2-3):199-203.
1992: N J Mallard; Alan L Hudson; David J Nutt
Characterization and autoradiographical localization of non-adrenoceptor idazoxan binding sites in the rat brain.
British journal of pharmacology 1992;106(4):1019-27.
1992: H C Jackson; I J Griffin; David J Nutt
Endogenous opioids may be involved in idazoxan-induced food intake.
Neuropharmacology 1992;31(8):771-6.
1992: H C Jackson; E Ramsay; David J Nutt
Attenuation of the behavioural effects of ethanol in mice by des-enkephalin-gamma-endorphin (ORG 5878).
Alcohol and alcoholism (Oxford, Oxfordshire) 1992;27(4):373-9.
1992: H C Jackson; I J Griffin; S D Birkett; David J Nutt
The effects of idazoxan and other alpha 2-adrenoceptor antagonists on urine output in the rat.
British journal of pharmacology 1992;106(2):443-6.
1992: D N Thomas; David J Nutt; R B Holman
Effects of acute and chronic electroconvulsive shock on noradrenaline release in the rat hippocampus and frontal cortex.
British journal of pharmacology 1992;106(2):430-4.
1992: H C Jackson; E Ramsay; David J Nutt
Effect of the cyclopyrrolones suriclone and RP 59037 on body temperature in mice.
European journal of pharmacology 1992;216(1):23-7.
1992: P Glue; S Wilson; G Campling; M Knightly; M Franklin; Philip J Cowen; David J Nutt
Alpha-2-adrenoceptor control of cortisol and ACTH in normal volunteers: preliminary open trial of the effects of acute and chronic idazoxan.
Psychoneuroendocrinology 1992;17(2-3):261-6.
1992: David J Nutt; C Lawson
Panic attacks. A neurochemical overview of models and mechanisms.
The British journal of psychiatry : the journal of mental science 1992;160():165-78.
1992: David J Nutt
Psychopharmacology of schizophrenia: Badgastein, Austria, 26 January-1 February 1992.
Journal of psychopharmacology (Oxford, England) 1992;6(4):536-40.
1992: Andrew P Smith; S J Wilson; P Glue; David J Nutt
The effects and after effects of the α2-adrenoceptor antagonist idazoxan on mood, memory and attention in normal volunteers.
Journal of psychopharmacology (Oxford, England) 1992;6(3):376-81.
1992: H C Jackson; David J Nutt
Strain differences in sensitivity to the hypothermic effects of benzodiazepine receptor ligands in mice.
Psychopharmacology 1992;109(3):365-8.
1992: H C Jackson; I J Griffin; David J Nutt
Alpha 2-adrenoceptor antagonists block the stimulant effects of cocaine in mice.
Life sciences 1992;50(19):PL155-9.
1992: Nicholas J Coupland; P Glue; David J Nutt
Challenge tests: assessment of the noradrenergic and GABA systems in depression and anxiety disorders.
Molecular aspects of medicine 1992;13(3):221-47.
1992: David J Nutt; C F Smith; R Bennett; H C Jackson
Investigations on the "set-point" theory of benzodiazepine receptor function.
Advances in biochemical psychopharmacology 1992;47():419-29.
1992: David J Nutt; P Glue; S Wilson; Nicholas J Coupland; A Lillywhite
Clinical correlates of benzodiazepine receptor function.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():679A-680A.
1992: P Glue; J Bailey; S Wilson; A Hudson; David J Nutt
Thyrotropin-releasing hormone selectively reverses lorazepam-induced sedation but not slowing of saccadic eye movements.
Life sciences 1992;50(6):PL25-30.
1991: H C Jackson; David J Nutt
Comparison of the effects of benzodiazepine and beta-carboline inverse agonists on body temperature in mice.
European journal of pharmacology 1991;205(2):213-6.
1991: H C Jackson; I J Griffin; David J Nutt
The effects of idazoxan and other alpha 2-adrenoceptor antagonists on food and water intake in the rat.
British journal of pharmacology 1991;104(1):258-62.
1991: H C Jackson; David J Nutt
Investigation of the different types of opioid receptor involved in electroconvulsive shock-induced antinociception and catalepsy in the rat.
The Journal of pharmacy and pharmacology 1991;43(9):640-3.
1991: H C Jackson; T L Ripley; S L Dickinson; David J Nutt
Anticonvulsant activity of the imidazoline 6,7-benzoidazoxan.
Epilepsy research 1991;9(2):121-6.
1991: H C Jackson; David J Nutt
Inhibition of baclofen-induced hypothermia in mice by the novel GABAB antagonist CGP 35348.
Neuropharmacology 1991;30(5):535-8.
1991: H C Jackson; David J Nutt
Effect of benzodiazepine and beta-carboline antagonists and partial agonists on loprazolam- and ZK 93423-induced hypothermia.
European journal of pharmacology 1991;193(2):179-84.
1991: P Glue; C Lawson; G Campling; Philip J Cowen; Mike Franklin; S Wilson; David J Nutt
Acute and chronic idazoxan in normal volunteers: biochemical, physiological and psychological effects.
Journal of psychopharmacology (Oxford, England) 1991;5(4):396-403.
1991: H C Jackson; David J Nutt
Involvement of μ-opioid receptors in electroconvulsive shock-induced antinociception in the rat.
Journal of psychopharmacology (Oxford, England) 1991;5(4):376.
1991: S J Wilson; P Glue; David J Nutt
The effects of the α2-adrenoceptor antagonist idazoxan on sleep in normal volunteers.
Journal of psychopharmacology (Oxford, England) 1991;5(2):105-10.
1991: P Glue; E White; S Wilson; D M Ball; David J Nutt
Pharmacology of saccadic eye movements in man. 2. Effects of the alpha 2-adrenoceptor ligands idazoxan and clonidine.
Psychopharmacology 1991;105(3):368-73.
1991: H C Jackson; S L Dickinson; David J Nutt
Exploring the pharmacology of the pro-convulsant effects of alpha 2-adrenoceptor antagonists in mice.
Psychopharmacology 1991;105(4):558-62.
1991: P Glue; N Payvandi; Gillian Kay; J M Elliott; David J Nutt
Effects of chronic alpha 2-adrenoceptor blockade on platelet and lymphocyte adrenoceptor binding in normal volunteers.
Life sciences 1991;49(8):PL21-5.
1991: D M Ball; P Glue; S Wilson; David J Nutt
Pharmacology of saccadic eye movements in man. 1. Effects of the benzodiazepine receptor ligands midazolam and flumazenil.
Psychopharmacology 1991;105(3):361-7.
1991: H C Jackson; David J Nutt
Differential effects of selective mu-, kappa- and delta-opioid antagonists on electroshock seizure threshold in mice.
Psychopharmacology 1991;103(3):380-3.
1990: David J Nutt; P Glue; C Lawson; Sue Wilson
Flumazenil provocation of panic attacks. Evidence for altered benzodiazepine receptor sensitivity in panic disorder.
Archives of general psychiatry 1990;47(10):917-25.
1990: P Glue; David J Nutt
Overexcitement and disinhibition. Dynamic neurotransmitter interactions in alcohol withdrawal.
The British journal of psychiatry : the journal of mental science 1990;157():491-9.
1990: H C Jackson; David J Nutt
Body temperature discriminates between full and partial benzodiazepine receptor agonists.
European journal of pharmacology 1990;185(2-3):243-6.
1990: David J Nutt
Pharmacological mechanisms of benzodiazepine withdrawal.
Journal of psychiatric research 1990;24 Suppl 2():105-10.
1990: H C Jackson; D M Ball; David J Nutt
Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality.
Life sciences 1990;47(4):353-9.
1990: David J Nutt; P Glue; C Lawson
The neurochemistry of anxiety: an update.
Progress in neuro-psychopharmacology & biological psychiatry 1990;14(5):737-52.
1989: H C Jackson; T L Ripley; David J Nutt
Exploring delta-receptor function using the selective opioid antagonist naltrindole.
Neuropharmacology 1989;28(12):1427-30.
1989: David J Nutt; C Lawson; P Glue
Attitudes to anxiety.
The British journal of psychiatry : the journal of mental science 1989;155():268.
1989: David J Nutt
Endocrine response to syncope in panic disorder.
Psychiatry research 1989;28(3):351-3.