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Pål Nyrén

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Farbod Babrzadeh; W Jeffrey Fessel; Tommy F Liu; Pål Nyrén; Mary Pacold; Celia Schiffer; Vici Varghese; Robert W Shafer
Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance.
Mehdi Javanmard; Pål Nyrén; Farbod Babrzadeh; Ronald W Davis
Improvement in cell capture throughput using parallel bioactivated microfluidic channels.
Michael Akhras; Magnus Unemo; Sreedevi Thiyagarajan; Pål Nyrén; Ronald W Davis; Andrew Fire; Nader Pourmand
Connector inversion probe technology: a powerful one-primer multiplex DNA amplification system for numerous scientific applications.

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All Publications

2013: Farbod Babrzadeh; W Jeffrey Fessel; Tommy F Liu; Pål Nyrén; Mary Pacold; Celia Schiffer; Vici Varghese; Robert W Shafer
Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance.
The Journal of antimicrobial chemotherapy 2013;68(2):414-8.
2012: Mehdi Javanmard; Pål Nyrén; Farbod Babrzadeh; Ronald W Davis
Improvement in cell capture throughput using parallel bioactivated microfluidic channels.
Biomedical microdevices 2012;14(4):625-9.
2007: Michael Akhras; Magnus Unemo; Sreedevi Thiyagarajan; Pål Nyrén; Ronald W Davis; Andrew Fire; Nader Pourmand
Connector inversion probe technology: a powerful one-primer multiplex DNA amplification system for numerous scientific applications.
PloS one 2007;2(9):e915.
2007: Michael Akhras; Sreedevi Thiyagarajan; Andrea C Villablanca; Ronald W Davis; Pål Nyrén; Nader Pourmand
PathogenMip assay: a multiplex pathogen detection assay.
PloS one 2007;2(2):e223.
2007: Pål Nyrén
The history of pyrosequencing.
Methods in molecular biology (Clifton, N.J.) 2007;373():1-14.
2006: Baback Gharizadeh; Michael Akhras; Nader Nourizad; Mehran Ghaderi; Kenji Yasuda; Pål Nyrén; Nader Pourmand
Methodological improvements of pyrosequencing technology.
Journal of biotechnology 2006;124(3):504-11.
2006: Baback Gharizadeh; Biying Zheng; Michael Akhras; Mehran Ghaderi; Olufisayo Jejelowo; Björn Strander; Pål Nyrén; Keng-Ling Wallin; Nader Pourmand
Sentinel-base DNA genotyping using multiple sequencing primers for high-risk human papillomaviruses.
Molecular and cellular probes 2006;20(3-4):230-8.
2005: Baback Gharizadeh; Michael Akhras; Magnus Unemo; Bengt Wretlind; Pål Nyrén; Nader Pourmand
Detection of gyrA mutations associated with ciprofloxacin resistance in Neisseria gonorrhoeae by rapid and reliable pre-programmed short DNA sequencing.
International journal of antimicrobial agents 2005;26(6):486-90.
2005: Baback Gharizadeh; Maria Oggionni; Biying Zheng; Eniko Akom; Nader Pourmand; Afshin Ahmadian; Keng-Ling Wallin; Pål Nyrén
Type-specific multiple sequencing primers: a novel strategy for reliable and rapid genotyping of human papillomaviruses by pyrosequencing technology.
The Journal of molecular diagnostics : JMD 2005;7(2):198-205.
2005: Emma Lindbäck; Baback Gharizadeh; Ferda Ataker; Asa Airell; Shah Jalal; Pål Nyrén; Bengt Wretlind
DNA gyrase gene in Neisseria gonorrhoeae as indicator for resistance to ciprofloxacin and species verification.
International journal of STD & AIDS 2005;16(2):142-7.
2004: Baback Gharizadeh; Jonas Eriksson; Nader Nourizad; Tommy Nordström; Pål Nyrén
Improvements in Pyrosequencing technology by employing Sequenase polymerase.
Analytical biochemistry 2004;330(2):272-80.
2004: Anna Svantesson; Pål O Westermark; Jeanette Hellgren Kotaleski; Baback Gharizadeh; Anders Lansner; Pål Nyrén
A mathematical model of the Pyrosequencing reaction system.
Biophysical chemistry 2004;110(1-2):129-45.
2004: Maria Ehn; Nader Nourizad; Kristina Bergström; Afshin Ahmadian; Pål Nyrén; Joakim Lundeberg; Sophia Hober
Toward pyrosequencing on surface-attached genetic material by use of DNA-binding luciferase fusion proteins.
Analytical biochemistry 2004;329(1):11-20.
2004: Baback Gharizadeh; E Norberg; J Löffler; S Jalal; J Tollemar; Hermann Einsele; Lena Klingspor; Pål Nyrén
Identification of medically important fungi by the Pyrosequencing technology.
Mycoses 2004;47(1-2):29-33.
2004: Jonas Eriksson; Baback Gharizadeh; Nader Nourizad; Pål Nyrén
7-Deaza-2'-deoxyadenosine-5'-triphosphate as an alternative nucleotide for the pyrosequencing technology.
Nucleosides, nucleotides & nucleic acids 2004;23(10):1583-94.
2004: Jonas Eriksson; Baback Gharizadeh; Tommy Nordström; Pål Nyrén
Pyrosequencing trade mark technology at elevated temperature.
Electrophoresis 2004;25(1):20-7.
2003: Baback Gharizadeh; Max Käller; Pål Nyrén; Anders Andersson; Mathias Uhlén; Joakim Lundeberg; Afshin Ahmadian
Viral and microbial genotyping by a combination of multiplex competitive hybridization and specific extension followed by hybridization to generic tag arrays.
Nucleic acids research 2003;31(22):e146.
2003: Xiaoyan Zhao; Baback Gharizadeh; Peter Hjelmstrom; Ritva Pirskanen; Pål Nyrén; Ann Kari Lefvert; Mehran Ghaderi
Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis.
International journal of molecular medicine 2003;12(5):749-53.
2003: Baback Gharizadeh; Andreas Ohlin; Paula Mölling; Anders Bäckman; Bahram Amini; Per Olcén; Pål Nyrén
Multiple group-specific sequencing primers for reliable and rapid DNA sequencing.
Molecular and cellular probes 2003;17(4):203-10.
2003: Nader Nourizad; Baback Gharizadeh; Pål Nyrén
Method for clone checking.
Electrophoresis 2003;24(11):1712-5.
2003: Baback Gharizadeh; Mehran Ghaderi; Declan Donnelly; Bahram Amini; Keng-Ling Wallin; Pål Nyrén
Multiple-primer DNA sequencing method.
Electrophoresis 2003;24(7-8):1145-51.
2003: Jonas Eriksson; Tommy Nordström; Pål Nyrén
Method enabling firefly luciferase-based bioluminometric assays at elevated temperatures.
Analytical biochemistry 2003;314(1):158-61.
2003: Nader Nourizad; Maria Ehn; Baback Gharizadeh; Sophia Hober; Pål Nyrén
Methylotrophic yeast Pichia pastoris as a host for production of ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum).
Protein expression and purification 2003;27(2):229-37.
2002: Tommy Nordström; Anders Alderborn; Pål Nyrén
Method for one-step preparation of double-stranded DNA template applicable for use with Pyrosequencing technology.
Journal of biochemical and biophysical methods 2002;52(2):71-82.
2002: Baback Gharizadeh; Tommy Nordström; Afshin Ahmadian; Mostafa Ronaghi; Pål Nyrén
Long-read pyrosequencing using pure 2'-deoxyadenosine-5'-O'-(1-thiotriphosphate) Sp-isomer.
Analytical biochemistry 2002;301(1):82-90.
2001: Jonas Eriksson; S Karamohamed; Pål Nyrén
Method for real-time detection of inorganic pyrophosphatase activity.
Analytical biochemistry 2001;293(1):67-70.
2001: Baback Gharizadeh; M Kalantari; C A Garcia; B Johansson; Pål Nyrén
Typing of human papillomavirus by pyrosequencing.
Laboratory investigation; a journal of technical methods and pathology 2001;81(5):673-9.
2001: M Nygren; Mostafa Ronaghi; Pål Nyrén; Jan Albert; Joakim Lundeberg
Quantification of HIV-1 using multiple quantitative polymerase chain reaction standards and bioluminometric detection.
Analytical biochemistry 2001;288(1):28-38.
2000: C A Garcia; Afshin Ahmadian; Baback Gharizadeh; Joakim Lundeberg; Mostafa Ronaghi; Pål Nyrén
Mutation detection by pyrosequencing: sequencing of exons 5-8 of the p53 tumor suppressor gene.
Gene 2000;253(2):249-57.
2000: Tommy Nordström; K Nourizad; Mostafa Ronaghi; Pål Nyrén
Method enabling pyrosequencing on double-stranded DNA.
Analytical biochemistry 2000;282(2):186-93.
2000: Afshin Ahmadian; Baback Gharizadeh; Anna C Gustafsson; Fredrik Sterky; Pål Nyrén; Mathias Uhlén; Joakim Lundeberg
Single-nucleotide polymorphism analysis by pyrosequencing.
Analytical biochemistry 2000;280(1):103-10.
2000: Tommy Nordström; Mostafa Ronaghi; L Forsberg; U de Faire; Ralf Morgenstern; Pål Nyrén
Direct analysis of single-nucleotide polymorphism on double-stranded DNA by pyrosequencing.
Biotechnology and applied biochemistry 2000;31 ( Pt 2)():107-12.
2000: Afshin Ahmadian; Joakim Lundeberg; Pål Nyrén; Mathias Uhlén; Mostafa Ronaghi
Analysis of the p53 tumor suppressor gene by pyrosequencing.
BioTechniques 2000;28(1):140-4, 146-7.
1999: S Karamohamed; Pål Nyrén
Real-time detection and quantification of adenosine triphosphate sulfurylase activity by a bioluminometric approach.
Analytical biochemistry 1999;271(1):81-5.
1999: S Karamohamed; Tommy Nordström; Pål Nyrén
Real-time bioluminometric method for detection of nucleoside diphosphate kinase activity.
BioTechniques 1999;26(4):728-34.
1999: S Karamohamed; J Nilsson; K Nourizad; Mostafa Ronaghi; Bertil Pettersson; Pål Nyrén
Production, purification, and luminometric analysis of recombinant Saccharomyces cerevisiae MET3 adenosine triphosphate sulfurylase expressed in Escherichia coli.
Protein expression and purification 1999;15(3):381-8.
1999: Mostafa Ronaghi; M Nygren; Joakim Lundeberg; Pål Nyrén
Analyses of secondary structures in DNA by pyrosequencing.
Analytical biochemistry 1999;267(1):65-71.
1998: Mostafa Ronaghi; Bertil Pettersson; Mathias Uhlén; Pål Nyrén
PCR-introduced loop structure as primer in DNA sequencing.
BioTechniques 1998;25(5):876-8, 880-2, 884.
1998: Mostafa Ronaghi; Mathias Uhlén; Pål Nyrén
A sequencing method based on real-time pyrophosphate.
Science (New York, N.Y.) 1998;281(5375):363, 365.
1998: S Karamohamed; Mostafa Ronaghi; Pål Nyrén
Bioluminometric method for real-time detection of reverse transcriptase activity.
BioTechniques 1998;24(2):302-6.
1997: Pål Nyrén; S Karamohamed; Mostafa Ronaghi
Detection of single-base changes using a bioluminometric primer extension assay.
Analytical biochemistry 1997;244(2):367-73.
1996: Mostafa Ronaghi; S Karamohamed; Bertil Pettersson; Mathias Uhlén; Pål Nyrén
Real-time DNA sequencing using detection of pyrophosphate release.
Analytical biochemistry 1996;242(1):84-9.
1994: Pål Nyrén; V Edwin
Inorganic pyrophosphatase-based detection systems. II. Detection and quantification of cell lysis and cell-lysing activity.
Analytical biochemistry 1994;220(1):46-52.
1994: Pål Nyrén; V Edwin
Inorganic pyrophosphatase-based detection systems. I. Detection and enumeration of cells.
Analytical biochemistry 1994;220(1):39-45.
1994: Pål Nyrén
Apyrase immobilized on paramagnetic beads used to improve detection limits in bioluminometric ATP monitoring.
Journal of bioluminescence and chemiluminescence 1994;9(1):29-34.
1993: Pål Nyrén; Bertil Pettersson; Mathias Uhlén
Solid phase DNA minisequencing by an enzymatic luminometric inorganic pyrophosphate detection assay.
Analytical biochemistry 1993;208(1):171-5.