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Toshiyuki Obata

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Motoyuki Kondo; Satoshi Ugi; Katsutaro Morino; Tomoya Fuke; Toshiyuki Obata; Takeshi Yoshizaki; Yoshihiko Nishio; Shiro Maeda; Atsunori Kashiwagi; Hiroshi Maegawa
Postprandial activation of protein kinase Cµ regulates the expression of adipocytokines via the transcription factor AP-2β.
Itsuko Miyazawa; Shin-ichi Araki; Toshiyuki Obata; Takeshi Yoshizaki; Katsutaro Morino; Aya Kadota; Satoshi Ugi; Hiromichi Kawai; Takashi Uzu; Yoshihiko Nishio; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi; Hiroshi Maegawa
Association between serum soluble TNFα receptors and renal dysfunction in type 2 diabetic patients without proteinuria.
Satoshi Ugi; Yoshihiko Nishio; Hiroshi Yamamoto; Kazuhiro Ikeda; Masaaki Kobayashi; Shuichi Tsukada; Motoyuki Kondo; Katsutaro Morino; Toshiyuki Obata; Takeshi Yoshizaki; Takashi Uzu; Hiroyuki Naitoh; Toru Tani; Shiro Maeda; Atsunori Kashiwagi; Hiroshi Maegawa
Relation of the expression of transcriptional factor TFAP2B to that of adipokines in subcutaneous and omental adipose tissues.

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All Publications

2011: Motoyuki Kondo; Satoshi Ugi; Katsutaro Morino; Tomoya Fuke; Toshiyuki Obata; Takeshi Yoshizaki; Yoshihiko Nishio; Shiro Maeda; Atsunori Kashiwagi; Hiroshi Maegawa
Postprandial activation of protein kinase Cµ regulates the expression of adipocytokines via the transcription factor AP-2β.
International journal of molecular medicine 2011;28(1):95-100.
2011: Itsuko Miyazawa; Shin-ichi Araki; Toshiyuki Obata; Takeshi Yoshizaki; Katsutaro Morino; Aya Kadota; Satoshi Ugi; Hiromichi Kawai; Takashi Uzu; Yoshihiko Nishio; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi; Hiroshi Maegawa
Association between serum soluble TNFα receptors and renal dysfunction in type 2 diabetic patients without proteinuria.
Diabetes research and clinical practice 2011;92(2):174-80.
2010: Satoshi Ugi; Yoshihiko Nishio; Hiroshi Yamamoto; Kazuhiro Ikeda; Masaaki Kobayashi; Shuichi Tsukada; Motoyuki Kondo; Katsutaro Morino; Toshiyuki Obata; Takeshi Yoshizaki; Takashi Uzu; Hiroyuki Naitoh; Toru Tani; Shiro Maeda; Atsunori Kashiwagi; Hiroshi Maegawa
Relation of the expression of transcriptional factor TFAP2B to that of adipokines in subcutaneous and omental adipose tissues.
Obesity (Silver Spring, Md.) 2010;18(7):1277-82.
2010: T Fuke; Takeshi Yoshizaki; M Kondo; Katsutaro Morino; Toshiyuki Obata; Satoshi Ugi; Yoshihiko Nishio; Shiro Maeda; Atsunori Kashiwagi; Hiroshi Maegawa
Transcription factor AP-2beta inhibits expression and secretion of leptin, an insulin-sensitizing hormone, in 3T3-L1 adipocytes.
International journal of obesity (2005) 2010;34(4):670-8.
2009: Yasushi Omura; Yoshihiko Nishio; Tadashi Takemoto; Chikako Ikeuchi; Osamu Sekine; Katsutaro Morino; Yasuhiro Maeno; Toshiyuki Obata; Satoshi Ugi; Hiroshi Maegawa; Hiroshi Kimura; Atsunori Kashiwagi
SAFB1, an RBMX-binding protein, is a newly identified regulator of hepatic SREBP-1c gene.
BMB reports 2009;42(4):232-7.
2009: Motoyuki Kondo; Hiroshi Maegawa; Toshiyuki Obata; Satoshi Ugi; Kazuhiro Ikeda; Katsutaro Morino; Yukie Nakai; Yoshihiko Nishio; Shiro Maeda; Atsunori Kashiwagi
Transcription factor activating protein-2beta: a positive regulator of monocyte chemoattractant protein-1 gene expression.
Endocrinology 2009;150(4):1654-61.
2004: Satoshi Ugi; Takeshi Imamura; Hiroshi Maegawa; Katsuya Egawa; Takeshi Yoshizaki; Kun Shi; Toshiyuki Obata; Yousuke Ebina; Atsunori Kashiwagi; Jerrold M Olefsky
Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
Molecular and cellular biology 2004;24(19):8778-89.
2002: Katsuya Egawa; Hiroshi Maegawa; Kun Shi; Takaaki Nakamura; Toshiyuki Obata; Takeshi Yoshizaki; Katsutaro Morino; Shinya Shimizu; Yoshihiko Nishio; Eiji Suzuki; Atsunori Kashiwagi
Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.
The Journal of biological chemistry 2002;277(41):38863-9.
1999: Hiroshi Maegawa; M Hasegawa; S Sugai; Toshiyuki Obata; Satoshi Ugi; Katsutaro Morino; Katsuya Egawa; T Fujita; T Sakamoto; Yoshihiko Nishio; H Kojima; Masakazu Haneda; H Yasuda; Ryuichi Kikkawa; Atsunori Kashiwagi
Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance.
The Journal of biological chemistry 1999;274(42):30236-43.
1999: Hiroshi Maegawa; Toshiyuki Obata; T Shibata; T Fujita; Satoshi Ugi; Katsutaro Morino; Yoshihiko Nishio; Hideto Kojima; Hideki Hidaka; Masakazu Haneda; Hitoshi Yasuda; Ryuichi Kikkawa; Atsunori Kashiwagi
A new antidiabetic agent (JTT-501) rapidly stimulates glucose disposal rates by enhancing insulin signal transduction in skeletal muscle.
Diabetologia 1999;42(2):151-9.
1998: Toshiyuki Obata; Hiroshi Maegawa; Atsunori Kashiwagi; T S Pillay; Ryuichi Kikkawa
High glucose-induced abnormal epidermal growth factor signaling.
Journal of biochemistry 1998;123(5):813-20.
1996: Toshiyuki Obata; Atsunori Kashiwagi; Hiroshi Maegawa; Yoshihiko Nishio; Satoshi Ugi; Hideki Hidaka; Ryuichi Kikkawa
Insulin signaling and its regulation of system A amino acid uptake in cultured rat vascular smooth muscle cells.
Circulation research 1996;79(6):1167-76.
1996: Hiroshi Maegawa; Atsunori Kashiwagi; T Fujita; Satoshi Ugi; M Hasegawa; Toshiyuki Obata; Yoshihiko Nishio; Hideto Kojima; Hideki Hidaka; Ryuichi Kikkawa
SHPTP2 serves adapter protein linking between Janus kinase 2 and insulin receptor substrates.
Biochemical and biophysical research communications 1996;228(1):122-7.
1995: M Iwanishi; Toshiyuki Obata; S Yamada; Hiroshi Maegawa; R Tachikawa-Ide; Satoshi Ugi; M Hasegawa; Hideto Kojima; T Oguni; R Toudo
Clinical and laboratory characteristics in the families with diabetes and a mitochondrial tRNA(LEU(UUR)) gene mutation.
Diabetes research and clinical practice 1995;29(2):75-82.