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Carole Ober

Research Profile

Disorders

Asthma

Physiology

Genes & Molecular Sequences

Chemicals & Drugs

Geographic Areas

South Dakota

Concepts & Ideas

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Publications

TOP 3
Minal Calışkan; Gaixin Du; James E Gern; Daniel J Jackson; Eskil Kreiner-Møller; Robert F Lemanske; Dan L Nicolae; Hans Bisgaard; Yury A Bochkov; Klaus Bønnelykke; Michelle M Stein; Carole Ober
Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.
Dagan A Loisel; Kathleen Murray; Christine Billstrand; Tinnakorn chaiworapongsa; Kristen Patterson; Roberto Romero; Carole Ober
The maternal HLA-G 1597ΔC null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women.
David Ding; Mahmoud Ismail; Helen Kay; Shawn Levy; Marshall D Lindheimer; Kathleen Murray; Dan L Nicolae; Roberto Romero; Nicole M Scott; Emma E Thompson; Raul Torres; Christine Billstrand; Tinnakorn chaiworapongsa; Phillip J Dexheimer; Carole Ober
Increased protein-coding mutations in the mitochondrial genome of African American women with preeclampsia.

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All Publications

2013: Minal Calışkan; Gaixin Du; James E Gern; Daniel J Jackson; Eskil Kreiner-Møller; Robert F Lemanske; Dan L Nicolae; Hans Bisgaard; Yury A Bochkov; Klaus Bønnelykke; Michelle M Stein; Carole Ober
Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.
The New England journal of medicine 2013;368(15):1398-407.
2013: Dagan A Loisel; Kathleen Murray; Christine Billstrand; Tinnakorn chaiworapongsa; Kristen Patterson; Roberto Romero; Carole Ober
The maternal HLA-G 1597ΔC null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women.
Molecular human reproduction 2013;19(3):144-52.
2012: David Ding; Mahmoud Ismail; Helen Kay; Shawn Levy; Marshall D Lindheimer; Kathleen Murray; Dan L Nicolae; Roberto Romero; Nicole M Scott; Emma E Thompson; Raul Torres; Christine Billstrand; Tinnakorn chaiworapongsa; Phillip J Dexheimer; Carole Ober
Increased protein-coding mutations in the mitochondrial genome of African American women with preeclampsia.
Reproductive sciences (Thousand Oaks, Calif.) 2012;19(12):1343-51.
2012: Laure Ségurel; Guy Sella; Emma E Thompson; Aarti Venkat; Timothée Flutre; Kathryn Gamble; Jessica Lovstad; Susan W Margulis; Jill Moyse; Carole Ober; Steve Ross; Molly Przeworski
The ABO blood group is a trans-species polymorphism in primates.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(45):18493-8.
2012: Jessica X Chong; Rebecca Ouwenga; Darrel J Waggoner; Rebecca L Anderson; Carole Ober
A population-based study of autosomal-recessive disease-causing mutations in a founder population.
American journal of human genetics 2012;91(4):608-20.
2012: Xingnan Li; Wendy C Moore; Dan L Nicolae; Carole Ober; Dara G Torgerson; Sally E Wenzel; Elizabeth J Ampleford; Eugene R Bleecker; William W Busse; Mario Castro; Serpil C Erzurum; Gregory A Hawkins; Timothy Howard; Elliot Israel; Huashi Li; Deborah A Meyers
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
The Journal of allergy and clinical immunology 2012;130(4):861-8.e7.
2012: Dara G Torgerson; Sally E Wenzel; Carole Ober; William Rodríguez-Cintrón; José R Rodríguez-Santana; W Gerald Teague; Elizabeth J Ampleford; Pedro C Avila; Kathleen C Barnes; Eugene R Bleecker; Esteban González Burchard; William W Busse; Daniel Capurso; Mario Castro; Nancy J Cox; Celeste Eng; Serpil C Erzurum; Anne M Fitzpatrick; Jean G Ford; Benjamin Gaston; Christopher R Gignoux; Timothy Howard; Donglei Hu; Elliot Israel; Nizar N Jarjour; Xingnan Li; Rasika A Mathias; Deborah A Meyers; Wendy C Moore; Dan L Nicolae
Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
The Journal of allergy and clinical immunology 2012;130(3):622-629.e9.
2012: Raghed M Jassem; Dagan A Loisel; Wafaa Sadoon Shani; Maysoon Sharief; Christine Billstrand; Carole Ober
HLA-G polymorphisms and soluble HLA-G protein levels in women with recurrent pregnancy loss from Basrah province in Iraq.
Human immunology 2012;73(8):811-7.
2012: Gülüm Kosova; Craig S Niederberger; Gail S Prins; Nicole M Scott; Carole Ober
Genome-wide association study identifies candidate genes for male fertility traits in humans.
American journal of human genetics 2012;90(6):950-61.
2012: Lawrence H Uricchio; Jessica X Chong; Carole Ober; Kevin D Ross; Dan L Nicolae
Accurate imputation of rare and common variants in a founder population from a small number of sequenced individuals.
Genetic epidemiology 2012;36(4):312-9.
2012: Wynn K Meyer; Carole Ober; Barbara Arbeithuber; Thomas Ebner; Richard R Hudson; Irene Tiemann-Boege; Molly Przeworski
Evaluating the evidence for transmission distortion in human pedigrees.
Genetics 2012;191(1):215-32.
2012: Darren A Cusanovich; Sherryl De Leon; Christine Billstrand; Claudia Chavarria; Katelyn Michelini; Carole Ober; Athma A Pai; Xiang Zhou; Yoav Gilad
The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.
Human molecular genetics 2012;21(9):2111-23.
2012: Dara G Torgerson; Scott T Weiss; Benjamin A Raby; Kathleen C Barnes; Terri H beaty; Eugene R Bleecker; Daniel Capurso; Penelope E Graves; Ryan D Hernandez; Fernando D Martinez; Rasika A Mathias; Deborah A Meyers; Dan L Nicolae; Carole Ober
Resequencing candidate genes implicates rare variants in asthma susceptibility.
American journal of human genetics 2012;90(2):273-81.
2011: Lianne M Kurina; Diane S Lauderdale; John T Cacioppo; Louise C Hawkley; Kristen L Knutson; Carole Ober
Loneliness is associated with sleep fragmentation in a communal society.
Sleep 2011;34(11):1519-26.
2011: Caroline A Motika; Mark Abney; Lucille A Lester; Charalampos Papachristou; Carole Ober
Rising prevalence of asthma is sex-specific in a US farming population.
The Journal of allergy and clinical immunology 2011;128(4):774-9.
2011: Jessica X Chong; Zunyan Dai; A Afşin Oktay; Thomas W Prior; Kathryn J Swoboda; Carole Ober
A common spinal muscular atrophy deletion mutation is present on a single founder haplotype in the US Hutterites.
European journal of human genetics : EJHG 2011;19(10):1045-51.
2011: Dagan A Loisel; Zheng Tan; Christopher J Tisler; Michael D Evans; Ronald E Gangnon; James E Gern; Daniel J Jackson; Robert F Lemanske; Carole Ober
IFNG genotype and sex interact to influence the risk of childhood asthma.
The Journal of allergy and clinical immunology 2011;128(3):524-31.
2011: Carole Ober; Tsung-Chieh Yao
The genetics of asthma and allergic disease: a 21st century perspective.
Immunological reviews 2011;242(1):10-30.
2011: Charalampos Papachristou; Carole Ober; Mark Abney
Genetic variance components estimation for binary traits using multiple related individuals.
Genetic epidemiology 2011;35(5):291-302.
2011: Carole Ober; Donata Vercelli
Gene-environment interactions in human disease: nuisance or opportunity?
Trends in genetics : TIG 2011;27(3):107-15.
2010: Xiaoguang Sun; Shwu-Fan Ma; Michael S Wade; Carlos Flores; Maria Pino-Yanes; Jaideep Moitra; Carole Ober; Rick Kittles; Aliya N Husain; Jean G Ford; Joe G. N. Garcia
Functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility.
The Journal of allergy and clinical immunology 2010;126(2):241-9, 249.e1-3.
2010: Gülüm Kosova; Joseph K Pickrell; Joanna L Kelley; Patrick F McArdle; Alan R Shuldiner; Mark Abney; Carole Ober
The CFTR Met 470 allele is associated with lower birth rates in fertile men from a population isolate.
PLoS genetics 2010;6(6):e1000974.
2010: Steven R White; Dagan A Loisel; J F McConville; R Stern; Y Tu; Bertha Alicia Marroquin; Imre Noth; Carole Ober
Levels of soluble human leukocyte antigen-G are increased in asthmatic airways.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;35(4):925-7.
2010: Irene Pichler; Christian Fuchsberger; Christa Platzer; Minal Calişkan; Fabio Marroni; Peter P Pramstaller; Carole Ober
Drawing the history of the Hutterite population on a genetic landscape: inference from Y-chromosome and mtDNA genotypes.
European journal of human genetics : EJHG 2010;18(4):463-70.
2010: Emma E Thompson; Ying Sun; Dan L Nicolae; Carole Ober
Shades of gray: a comparison of linkage disequilibrium between Hutterites and Europeans.
Genetic epidemiology 2010;34(2):133-9.
2010: Gülüm Kosova; Mark Abney; Carole Ober
Colloquium papers: Heritability of reproductive fitness traits in a human population.
Proceedings of the National Academy of Sciences of the United States of America 2010;107 Suppl 1():1772-8.
2010: Emma E Thompson; Gabe Haller; Jayant M Pinto; Ying Sun; Bethanne Zelano; Suma Jacob; Martha K McClintock; Dan L Nicolae; Carole Ober
Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors.
Human immunology 2010;71(1):100-3.
2009: Gabe Haller; Dara G Torgerson; Carole Ober; Emma E Thompson
Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility.
The Journal of allergy and clinical immunology 2009;124(6):1204-9.e9.
2009: Carole Ober; Geoffrey L Chupp
The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases.
Current opinion in allergy and clinical immunology 2009;9(5):401-8.
2009: Adi Fledel-Alon; Daniel J Wilson; Karl W Broman; Xiaoquan Wen; Carole Ober; Graham Coop; Molly Przeworski
Broad-scale recombination patterns underlying proper disjunction in humans.
PLoS genetics 2009;5(9):e1000658.
2009: Carole Ober; Alex S Nord; Emma E Thompson; Lin Pan; Zheng Tan; Darren Cusanovich; Ying Sun; Raluca Nicolae; Celina Edelstein; Daniel H Schneider; Christine Billstrand; Ditta Pfaffinger; Natasha Phillips; Rebecca L Anderson; Binu Philips; Ramakrishnan Rajagopalan; Thomas S Hatsukami; Mark J Rieder; Patrick J Heagerty; Deborah A Nickerson; Mark Abney; Santica Marcovina; Gail P Jarvik; Angelo M Scanu; Dan L Nicolae
Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.
Journal of lipid research 2009;50(5):798-806.
2008: Carole Ober; Dagan A Loisel; Yoav Gilad
Sex-specific genetic architecture of human disease.
Nature reviews. Genetics 2008;9(12):911-22.
2008: Shwu-Fan Ma; Carlos Flores; Michael S Wade; Steven M Dudek; Dan L Nicolae; Carole Ober; Joe G. N. Garcia
A common cortactin gene variation confers differential susceptibility to severe asthma.
Genetic epidemiology 2008;32(8):757-66.
2008: Jayant M Pinto; M Geoffrey Hayes; Daniel Schneider; Robert M Naclerio; Carole Ober
A genomewide screen for chronic rhinosinusitis genes identifies a locus on chromosome 7q.
The Laryngoscope 2008;118(11):2067-72.
2008: D K Nolan; P Chen; Soma Das; Carole Ober; Darrel J Waggoner
Fine mapping of a locus for nonsyndromic mental retardation on chromosome 19p13.
American journal of medical genetics. Part A 2008;146A(11):1414-22.
2008: Carole Ober; Zheng Tan; Ying Sun; Jennifer D Possick; Lin Pan; Raluca Nicolae; Sadie Radford; Rodney R Parry; Andrea Heinzmann; Klaus A Deichmann; Lucille A Lester; James E Gern; Robert F Lemanske; Dan L Nicolae; Jack A Elias; Geoffrey L Chupp
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
The New England journal of medicine 2008;358(16):1682-91.
2008: Jayant M Pinto; Sanguansak Thanaviratananich; M Geoffrey Hayes; Robert M Naclerio; Carole Ober
A genome-wide screen for hyposmia susceptibility Loci.
Chemical senses 2008;33(4):319-29.
2008: Graham Coop; Xiaoquan Wen; Carole Ober; Jonathan K Pritchard; Molly Przeworski
High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans.
Science (New York, N.Y.) 2008;319(5868):1395-8.
2008: Alon B Neidich; Josh W Joseph; Carole Ober; Lainie Friedman Ross
Empirical data about women's attitudes towards a hypothetical pediatric biobank.
American journal of medical genetics. Part A 2008;146(3):297-304.
2008: Irene Gallego Romero; Carole Ober
CFTR mutations and reproductive outcomes in a population isolate.
Human genetics 2008;122(6):583-8.
2007: Zheng Tan; Glenn Randall; Jihua Fan; Blanca Camoretti-Mercado; Rebecca A Brockman-Schneider; Lin Pan; Julian Solway; James E Gern; Robert F Lemanske; Dan L Nicolae; Carole Ober
Allele-specific targeting of microRNAs to HLA-G and risk of asthma.
American journal of human genetics 2007;81(4):829-34.
2007: Anna Pluzhnikov; Daniel K Nolan; Zhiqiang Tan; Mary Sara McPeek; Carole Ober
Correlation of intergenerational family sizes suggests a genetic component of reproductive fitness.
American journal of human genetics 2007;81(1):165-9.
2007: Emma E Thompson; Lin Pan; Irina Ostrovnaya; Lauren A Weiss; James E Gern; Robert F Lemanske; Dan L Nicolae; Carole Ober
Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life.
The Journal of allergy and clinical immunology 2007;119(6):1423-9.
2007: Lin Pan; Carole Ober; Mark Abney
Heritability estimation of sex-specific effects on human quantitative traits.
Genetic epidemiology 2007;31(4):338-47.
2007: Carlos Flores; Shwu-Fan Ma; Karen Maresso; Carole Ober; Joe G. N. Garcia
A variant of the myosin light chain kinase gene is associated with severe asthma in African Americans.
Genetic epidemiology 2007;31(4):296-305.
2007: Jacqueline K Wittke-Thompson; Nicoline Ambrose; Ehud Yairi; Cheryl Roe; Edwin H Cook; Carole Ober; Nancy J Cox
Genetic studies of stuttering in a founder population.
Journal of fluency disorders 2007;32(1):33-50.
2006: Thorsten Kurz; Sabine Hoffjan; M Geoffrey Hayes; Dan Schneider; Raluca Nicolae; Andrea Heinzmann; Silvija-Pera Jerkic; Rodney Parry; Nancy J Cox; Klaus A Deichmann; Carole Ober
Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci.
The Journal of allergy and clinical immunology 2006;118(2):396-402.
2006: Lauren A Weiss; Gülüm Kosova; Ryan J Delahanty; Lan Jiang; Edwin H Cook; Carole Ober; James S Sutcliffe
Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility.
European journal of human genetics : EJHG 2006;14(8):923-31.
2006: Lauren A Weiss; Carole Ober; Edwin H Cook
ITGB3 shows genetic and expression interaction with SLC6A4.
Human genetics 2006;120(1):93-100.
2006: Carole Ober; Christine Billstrand; Susan Kuldanek; Zheng Tan
The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells.
Human reproduction (Oxford, England) 2006;21(7):1743-8.
2006: Carole Ober; Lin Pan; Natasha Phillips; Rodney Parry; Lianne M Kurina
Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population.
Current allergy and asthma reports 2006;6(3):241-6.
2006: A Chan; Dina L Newman; A M Shon; Daniel H Schneider; Susan Kuldanek; Carole Ober
Variation in the type I interferon gene cluster on 9p21 influences susceptibility to asthma and atopy.
Genes and immunity 2006;7(2):169-78.
2006: Carole Ober; Sabine Hoffjan
Asthma genetics 2006: the long and winding road to gene discovery.
Genes and immunity 2006;7(2):95-100.
2006: Lauren A Weiss; Lin Pan; Mark Abney; Carole Ober
The sex-specific genetic architecture of quantitative traits in humans.
Nature genetics 2006;38(2):218-22.
2006: Malcolm N Blumenthal; Carl D Langefeld; Kathleen C Barnes; Carole Ober; Deborah A Meyers; Richard A King; Terri H beaty; Stephanie R Beck; Eugene R Bleecker; Stephen S Rich
A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity.
The Journal of allergy and clinical immunology 2006;117(1):79-85.
2005: Zheng Tan; Andrew Minsoo Shon; Carole Ober
Evidence of balancing selection at the HLA-G promoter region.
Human molecular genetics 2005;14(23):3619-28.
2005: Carole Ober; Emma E Thompson
Rethinking genetic models of asthma: the role of environmental modifiers.
Current opinion in immunology 2005;17(6):670-8.
2005: Carole Ober
HLA-G: an asthma gene on chromosome 6p.
Immunology and allergy clinics of North America 2005;25(4):669-79.
2005: Jian Zhang; Daniel Schneider; Carole Ober; Mary Sara McPeek
Multilocus linkage disequilibrium mapping by the decay of haplotype sharing with samples of related individuals.
Genetic epidemiology 2005;29(2):128-40.
2005: Rebecca A Shilling; Jayant M Pinto; Donna C Decker; Daniel H Schneider; Hozefa S Bandukwala; Jeffrey R Schneider; Blanca Camoretti-Mercado; Carole Ober; Anne I Sperling
Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2061-5.
2005: Carole Ober
Perspectives on the past decade of asthma genetics.
The Journal of allergy and clinical immunology 2005;116(2):274-8.
2005: Lianne M Kurina; Lauren A Weiss; Steven W Graves; Rodney Parry; Gordon H Williams; Mark Abney; Carole Ober
Sex differences in the genetic basis of morning serum cortisol levels: genome-wide screen identifies two novel loci specific to women.
The Journal of clinical endocrinology and metabolism 2005;90(8):4747-52.
2005: Lauren A Weiss; Lucille A Lester; James E Gern; Raoul L Wolf; Rodney Parry; Robert F Lemanske; Julian Solway; Carole Ober
Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations.
American journal of respiratory and critical care medicine 2005;172(1):67-73.
2005: Lauren A Weiss; Mark Abney; Rodney Parry; Angelo M Scanu; Edwin H Cook; Carole Ober
Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample.
Human genetics 2005;117(1):81-7.
2005: Sabine Hoffjan; Dan L Nicolae; Irina Ostrovnaya; Kathy A Roberg; Michael Evans; Daniel B Mirel; Lori Steiner; Karen Walker; Peter A Shult; Ronald E Gangnon; James E Gern; Fernando D Martinez; Robert F Lemanske; Carole Ober
Gene-environment interaction effects on the development of immune responses in the 1st year of life.
American journal of human genetics 2005;76(4):696-704.
2005: Dan L Nicolae; Nancy J Cox; Lucille A Lester; Daniel Schneider; Zheng Tan; Christine Billstrand; Susan Kuldanek; Joseph Donfack; Paul Kogut; Nina M Patel; Jeffrey Goodenbour; Timothy Howard; Raoul Wolf; Gerard H Koppelman; Steven R White; Rodney Parry; Dirkje S Postma; Deborah A Meyers; Eugene R Bleecker; Joan S Hunt; Julian Solway; Carole Ober
Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21.
American journal of human genetics 2005;76(2):349-57.
2005: Joseph Donfack; Daniel H Schneider; Zheng Tan; Thorsten Kurz; Inna Dubchak; Kelly A Frazer; Carole Ober
Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy.
Respiratory research 2005;6():145.
2005: Martha K McClintock; Susan B Bullivant; Suma Jacob; Natasha Spencer; Bethanne Zelano; Carole Ober
Human body scents: conscious perceptions and biological effects.
Chemical senses 2005;30 Suppl 1():i135-7.
2005: Lauren A Weiss; Mark Abney; Edwin H Cook; Carole Ober
Sex-specific genetic architecture of whole blood serotonin levels.
American journal of human genetics 2005;76(1):33-41.
2004: Catherine Bourgain; Mark Abney; Daniel Schneider; Carole Ober; Mary Sara McPeek
Testing for Hardy-Weinberg equilibrium in samples with related individuals.
Genetics 2004;168(4):2349-61.
2004: Lauren A Weiss; Jeremy Veenstra-VanderWeele; Dina L Newman; Soo-Jeong Kim; Harvey Dytch; Mary Sara McPeek; Suzanne Cheng; Carole Ober; Edwin H Cook; Mark Abney
Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin.
European journal of human genetics : EJHG 2004;12(11):949-54.
2004: Thorsten Kurz; Carole Ober
The role of environmental tobacco smoke in genetic susceptibility to asthma.
Current opinion in allergy and clinical immunology 2004;4(5):335-9.
2004: William B Dobyns; Allison Filauro; Brett N Tomson; April S Chan; Allen W Ho; Nicholas T Ting; Jan C Oosterwijk; Carole Ober
Inheritance of most X-linked traits is not dominant or recessive, just X-linked.
American journal of medical genetics. Part A 2004;129A(2):136-43.
2004: Dina L Newman; Sabine Hoffjan; Catherine Bourgain; Mark Abney; Raluca Nicolae; Elle T Profits; Michael A Grow; Karen Walker; Lori Steiner; Rodney Parry; Rebecca Reynolds; Mary Sara McPeek; Suzanne Cheng; Carole Ober
Are common disease susceptibility alleles the same in outbred and founder populations?
European journal of human genetics : EJHG 2004;12(7):584-90.
2004: Mary Sara McPeek; Xiaodong Wu; Carole Ober
Best linear unbiased allele-frequency estimation in complex pedigrees.
Biometrics 2004;60(2):359-67.
2004: Malcolm N Blumenthal; Carole Ober; Terri H beaty; Eugene R Bleecker; Carl D Langefeld; Richard A King; Lucille A Lester; N Cox; Kathleen C Barnes; Alkis Togias; Rasika A Mathias; Deborah A Meyers; William S Oetting; Stephen S Rich
Genome scan for loci linked to mite sensitivity: the Collaborative Study on the Genetics of Asthma (CSGA).
Genes and immunity 2004;5(3):226-31.
2004: Sabine Hoffjan; Irina Ostrovnaja; Dan L Nicolae; Dina L Newman; Raluca Nicolae; Ronald E Gangnon; Lori Steiner; Karen Walker; Rebecca Reynolds; Deborah Greene; Daniel Mirel; James E Gern; Robert F Lemanske; Carole Ober
Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy.
The Journal of allergy and clinical immunology 2004;113(3):511-8.
2004: James E Gern; Claudia L Reardon; Sabine Hoffjan; Dan L Nicolae; Zhanhai Li; Kathy A Roberg; William A Neaville; Kirstin T Carlson-Dakes; Kiva Adler; Rebekah Hamilton; Elizabeth Anderson; Stephanie Gilbertson-White; Christopher J Tisler; Douglas F Dasilva; Kelly Anklam; Lance D Mikus; Louis A Rosenthal; Carole Ober; Ronald E Gangnon; Robert F Lemanske
Effects of dog ownership and genotype on immune development and atopy in infancy.
The Journal of allergy and clinical immunology 2004;113(2):307-14.
2004: Sebastian K Zoellner ; Xiaoquan Wen; Neil A Hanchard; Mark A Herbert; Carole Ober; Jonathan K Pritchard
Evidence for extensive transmission distortion in the human genome.
American journal of human genetics 2004;74(1):62-72.
2004: Malcolm N Blumenthal; Carl D Langefeld; Terri H beaty; Eugene R Bleecker; Carole Ober; Lucille A Lester; Ethan M Lange; Kathleen C Barnes; Raoul Wolf; Richard A King; Julian Solway; William S Oetting; Deborah A Meyers; Stephen S Rich
A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma.
Human genetics 2004;114(2):157-64.
2003: Catherine Bourgain; Sabine Hoffjan; Raluca Nicolae; Dina Newman; Lori Steiner; Karen Walker; Rebecca Reynolds; Carole Ober; Mary Sara McPeek
Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus.
American journal of human genetics 2003;73(3):612-26.
2003: Amy E Sullivan; Tracey Lewis; Mary D Stephenson; Randall R Odem; James Schreiber; Carole Ober; D Ware Branch
Pregnancy outcome in recurrent miscarriage patients with skewed X chromosome inactivation.
Obstetrics and gynecology 2003;101(6):1236-42.
2003: Carole Ober; Carrie L Aldrich; Inna Chervoneva; Christine Billstrand; Fedik Rahimov; Heather L Gray; Terry Hyslop
Variation in the HLA-G promoter region influences miscarriage rates.
American journal of human genetics 2003;72(6):1425-35.
2003: Susan Colilla; Dan L Nicolae; Anna Pluzhnikov; Malcolm N Blumenthal; Terri H beaty; Eugene R Bleecker; Ethan M Lange; Stephen S Rich; Deborah A Meyers; Carole Ober; Nancy J Cox
Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure.
The Journal of allergy and clinical immunology 2003;111(4):840-6.
2003: Joseph Donfack; Paul Kogut; Sean M Forsythe; Julian Solway; Carole Ober
Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy.
The Journal of allergy and clinical immunology 2003;111(3):527-32.
2003: Dina L Newman; Mark Abney; Harvey Dytch; Rodney Parry; Mary Sara McPeek; Carole Ober
Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree.
Human molecular genetics 2003;12(2):137-44.
2003: Sabine Hoffjan; Dan L Nicolae; Carole Ober
Association studies for asthma and atopic diseases: a comprehensive review of the literature.
Respiratory research 2003;4():14.
2002: Sabine Hoffjan; Carole Ober
Present status on the genetic studies of asthma.
Current opinion in immunology 2002;14(6):709-17.
2002: Carrie Aldrich; Charles Wambebe; Lillian Odama; Anna Di Rienzo; Carole Ober
Linkage disequilibrium and age estimates of a deletion polymorphism (1597DeltaC) in HLA-G suggest non-neutral evolution.
Human immunology 2002;63(5):405-12.
2002: Mark Abney; Carole Ober; Mary Sara McPeek
Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites.
American journal of human genetics 2002;70(4):920-34.
2002: Suma Jacob; Martha K McClintock; Bethanne Zelano; Carole Ober
Paternally inherited HLA alleles are associated with women's choice of male odor.
Nature genetics 2002;30(2):175-9.
2001: H L Gray; E L Sorensen; Joan S Hunt; Carole Ober
Three polymorphisms in the 3' UTR of the TRAIL (TNF-related apoptosis-inducing ligand) gene.
Genes and immunity 2001;2(8):469-70.
2001: C L Aldrich; Mary D Stephenson; Theodore Karrison; Randall R Odem; D Ware Branch; JR Scott; JR Schreiber; Carole Ober
HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage.
Molecular human reproduction 2001;7(12):1167-72.
2001: Dina L Newman; Mark Abney; Mary Sara McPeek; Carole Ober; Nancy J Cox
The importance of genealogy in determining genetic associations with complex traits.
American journal of human genetics 2001;69(5):1146-8.
2001: Carole Ober; Mark Abney; Mary Sara McPeek
The genetic dissection of complex traits in a founder population.
American journal of human genetics 2001;69(5):1068-79.
2001: Lucille A Lester; Stephen S Rich; Malcolm N Blumenthal; Alkis Togias; S Murphy; Floyd J Malveaux; M E Miller; Georgia M Dunston; Julian Solway; Raoul L Wolf; Jonathan M Samet; DG Marsh; Deborah A Meyers; Carole Ober; Eugene R Bleecker
Ethnic differences in asthma and associated phenotypes: collaborative study on the genetics of asthma.
The Journal of allergy and clinical immunology 2001;108(3):357-62.
2001: Jianfeng Xu; Deborah A Meyers; Carole Ober; Malcolm N Blumenthal; Beverly G Mellen; Kathleen C Barnes; Richard A King; Lucille A Lester; Timothy Howard; Julian Solway; Carl D Langefeld; Terri H beaty; Stephen S Rich; Eugene R Bleecker; Nancy J Cox
Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma.
American journal of human genetics 2001;68(6):1437-46.
2001: Xiaodong Wu; Anna Di Rienzo; Carole Ober
A population genetics study of single nucleotide polymorphisms in the interleukin 4 receptor alpha (IL4RA) gene.
Genes and immunity 2001;2(3):128-34.
2001: Mark Abney; Mary Sara McPeek; Carole Ober
Broad and narrow heritabilities of quantitative traits in a founder population.
American journal of human genetics 2001;68(5):1302-7.
2001: Rasika A Mathias; LR Freidhoff; Malcolm N Blumenthal; Deborah A Meyers; Lucille A Lester; R King; Jianfeng Xu; J Solway; Kathleen C Barnes; J Pierce; O Colin Stine; Alkis Togias; William S Oetting; Patricia L Marshik; Jacqueline B Hetmanski; Shau-Ku Huang; Eva Ehrlich; Georgia M Dunston; Floyd J Malveaux; S Banks-Schlegel; Nancy J Cox; Eugene R Bleecker; Carole Ober; Terri H beaty; Stephen S Rich
Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families.
Genetic epidemiology 2001;20(3):340-55.
2001: Carole Ober
Susceptibility genes in asthma and allergy.
Current allergy and asthma reports 2001;1(2):174-9.
2001: Deborah A Meyers; Matthias Wjst; Carole Ober
Description of three data sets: Collaborative Study on the Genetics of Asthma (CSGA), the German Affected-Sib-Pair Study, and the Hutterites of South Dakota.
Genetic epidemiology 2001;21 Suppl 1():S4-8.
2000: Carole Ober; Anya Tsalenko; Rodney Parry; Nancy J Cox
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
American journal of human genetics 2000;67(5):1154-62.
2000: E Summerhill; S A Leavitt; H Gidley; Rodney Parry; Julian Solway; Carole Ober
beta(2)-adrenergic receptor Arg16/Arg16 genotype is associated with reduced lung function, but not with asthma, in the Hutterites.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):599-602.
2000: A C Eklund; M M Belchak; Karen A Lapidos; R Raha-Chowdhury; Carole Ober
Polymorphisms in the HLA-linked olfactory receptor genes in the Hutterites.
Human immunology 2000;61(7):711-7.
2000: Carole Ober; M F Moffatt
Contributing factors to the pathobiology. The genetics of asthma.
Clinics in chest medicine 2000;21(2):245-61.
2000: Joseph Donfack; Anya Tsalenko; DM Hoki; Rodney Parry; Julian Solway; Lucille A Lester; Carole Ober
HLA-DRB1*01 alleles are associated with sensitization to cockroach allergens.
The Journal of allergy and clinical immunology 2000;105(5):960-6.
2000: CL Aldrich; Marion S Verp; MA Walker; Carole Ober
A null mutation in HLA-G is not associated with preeclampsia or intrauterine growth retardation.
Journal of reproductive immunology 2000;47(1):41-8.
2000: Emmanuelle Génin; Carole Ober; LR Weitkamp; Glenys Thomson
A robust test for assortative mating.
European journal of human genetics : EJHG 2000;8(2):119-24.
2000: Mark Abney; Mary Sara McPeek; Carole Ober
Estimation of variance components of quantitative traits in inbred populations.
American journal of human genetics 2000;66(2):629-50.
2000: Carole Ober; S A Leavitt; Anya Tsalenko; Timothy Howard; DM Hoki; R Daniel; Dina L Newman; Xiaodong Wu; Rodney Parry; Lucille A Lester; Julian Solway; Malcolm N Blumenthal; Richard A King; Jianfeng Xu; Deborah A Meyers; Eugene R Bleecker; Nancy J Cox
Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations.
American journal of human genetics 2000;66(2):517-26.
1999: Carole Ober; Anya Tsalenko; S Willadsen; D Newman; R Daniel; Xiaodong Wu; J Andal; DM Hoki; Daniel Schneider; K True; C Schou; Rodney Parry; N Cox
Genome-wide screen for atopy susceptibility alleles in the Hutterites.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29 Suppl 4():11-5.
1999: Renate Nickel; S A Willadsen; LR Freidhoff; Shau-Ku Huang; Luis Caraballo; Raana P Naidu; Paul N Levett; Malcolm N Blumenthal; S Banks-Schlegel; Eugene R Bleecker; Terri H beaty; Carole Ober; Kathleen C Barnes
Determination of Duffy genotypes in three populations of African descent using PCR and sequence-specific oligonucleotides.
Human immunology 1999;60(8):738-42.
1999: Carole Ober; Theodore Karrison; Randall R Odem; Randall B Barnes; D Ware Branch; Mary D Stephenson; B Baron; MA Walker; JR Scott; JR Schreiber
Mononuclear-cell immunisation in prevention of recurrent miscarriages: a randomised trial.
Lancet 1999;354(9176):365-9.
1999: LR Weitkamp; Carole Ober
Ancestral and recombinant 16-locus HLA haplotypes in the Hutterites.
Immunogenetics 1999;49(6):491-7.
1999: Carole Ober
Studies of HLA, fertility and mate choice in a human isolate.
Human reproduction update 1999;5(2):103-7.
1999: A Robertson; D Charlesworth; Carole Ober
Effect of inbreeding avoidance on Hardy-Weinberg expectations: examples of neutral and selected loci.
Genetic epidemiology 1999;17(3):165-73.
1999: K A Kaufman; JA Bowen; A F Tsai; Jeffrey A Bluestone; Joan S Hunt; Carole Ober
The CTLA-4 gene is expressed in placental fibroblasts.
Molecular human reproduction 1999;5(1):84-7.
1999: Carole Ober; Terry Hyslop; W W Hauck
Inbreeding effects on fertility in humans: evidence for reproductive compensation.
American journal of human genetics 1999;64(1):225-31.
1998: Carrie Grimsley; K A Mather; Carole Ober
HLA-H: a pseudogene with increased variation due to balancing selection at neighboring loci.
Molecular biology and evolution 1998;15(12):1581-8.
1998: A F Tsai; K A Kaufman; MA Walker; Theodore Karrison; Randall R Odem; Randall B Barnes; JR Scott; JR Schreiber; Mary D Stephenson; Carole Ober
Transmission disequilibrium of maternally-inherited CTLA-4 microsatellite alleles in idiopathic recurrent miscarriage.
Journal of reproductive immunology 1998;40(2):147-57.
1998: Theodore Karrison; Carole Ober
Recurrent miscarriage (REMIS) study: how should data from women who do not become pregnant be handled?
Controlled clinical trials 1998;19(5):430-9.
1998: Carole Ober; Nancy J Cox; Mark Abney; Anna Di Rienzo; Eric S Lander; B Changyaleket; H Gidley; BS Kurtz; J Lee; M Nance; A Pettersson; J Prescott; A Richardson; E Schlenker; E Summerhill; S Willadsen; Rodney Parry
Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma.
Human molecular genetics 1998;7(9):1393-8.
1998: Blanca Camoretti-Mercado; Sean M Forsythe; Michelle M LeBeau; Rafael Espinosa; Joaquim Vieira; Andrew J Halayko; S Willadsen; BS Kurtz; Carole Ober; G A Evans; R Thweatt; S Shapiro; Q Niu; Y Qin; PA Padrid; Julian Solway
Expression and cytogenetic localization of the human SM22 gene (TAGLN).
Genomics 1998;49(3):452-7.
1998: Carole Ober; Nancy J Cox
The genetics of asthma. Mapping genes for complex traits in founder populations.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28 Suppl 1():101-5; discussion 108-10.
1998: Carole Ober; CL Aldrich; B Rosinsky; A Robertson; MA Walker; S Willadsen; Marion S Verp; D E Geraghty; Joan S Hunt
HLA-G1 protein expression is not essential for fetal survival.
Placenta 1998;19(2-3):127-32.
1998: Carole Ober
Do genetics play a role in the pathogenesis of asthma?
The Journal of allergy and clinical immunology 1998;101(2 Pt 2):S417-20.
1998: Carole Ober; Terry Hyslop; Sherman Elias; LR Weitkamp; W W Hauck
Human leukocyte antigen matching and fetal loss: results of a 10 year prospective study.
Human reproduction (Oxford, England) 1998;13(1):33-8.
1998: Carole Ober
HLA and pregnancy: the paradox of the fetal allograft.
American journal of human genetics 1998;62(1):1-5.
1997: Maria E Fisfalen; Keyoumars Soltani; E Kaplan; Ellen M Palmer; Gijs A van Seventer; Francis H Straus; M Diaz; Carole Ober; Leslie J DeGroot
Evaluating the role of Th0 and Th1 clones in autoimmune thyroid disease by use of Hu-SCID chimeras.
Clinical immunology and immunopathology 1997;85(3):253-64.
1997: Carole Ober; CL Aldrich
HLA-G polymorphisms: neutral evolution or novel function?
Journal of reproductive immunology 1997;36(1-2):1-21.
1997: Maria E Fisfalen; Ellen M Palmer; Gijs A van Seventer; Keyoumars Soltani; Y Sawai; E Kaplan; Y Hidaka; Carole Ober; Leslie J DeGroot
Thyrotropin-receptor and thyroid peroxidase-specific T cell clones and their cytokine profile in autoimmune thyroid disease.
The Journal of clinical endocrinology and metabolism 1997;82(11):3655-63.
1997: Carole Ober; LR Weitkamp; N Cox; Harvey Dytch; D Kostyu; Sherman Elias
HLA and mate choice in humans.
American journal of human genetics 1997;61(3):497-504.
1997: Carole Ober; K van der Ven
Immunogenetics of reproduction: an overview.
Current topics in microbiology and immunology 1997;222():1-23.
1997: Carrie Grimsley; Carole Ober
Population genetic studies of HLA-E: evidence for selection.
Human immunology 1997;52(1):33-40.
1996: Carole Ober; B Rosinsky; Carrie Grimsley; Katrin van der Ven; A Robertson; A Runge
Population genetic studies of HLA-G: allele frequencies and linkage disequilibrium with HLA-A1.
Journal of reproductive immunology 1996;32(2):111-23.
1996: Katrin van der Ven; L Messer; Hans van der Ven; RS Jeyendran; Carole Ober
Cystic fibrosis mutation screening in healthy men with reduced sperm quality.
Human reproduction (Oxford, England) 1996;11(3):513-7.
1995: Carole Ober
Current topic: HLA and reproduction: lessons from studies in the Hutterites.
Placenta 1995;16(7):569-77.
1995: Thomas Steck; Katrin van der Ven; J Kwak; Alan E Beer; Carole Ober
HLA-DQA1 and HLA-DQB1 haplotypes in aborted fetuses and couples with recurrent spontaneous abortion.
Journal of reproductive immunology 1995;29(2):95-104.
1995: Deborah V Dawson; Carole Ober; DD Kostyu
Extended HLA profile of an inbred isolate: the Schmiedeleut Hutterites of South Dakota.
Genetic epidemiology 1995;12(1):47-62.
1994: Katrin van der Ven; Carole Ober
HLA-G polymorphisms in African Americans.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5628-33.
1994: J M Bryttan; DD Kostyu; Carole Ober; S Elias; Deborah V Dawson
Analysis of HLA haplotype segregation in the Schmiedeleut Hutterites of South Dakota.
Human heredity 1994;44(4):181-90.
1994: L A Lester; J Kraut; J Lloyd-Still; T Karrison; C Mott; C Billstrand; A Lemke; Carole Ober
Delta F508 genotype does not predict disease severity in an ethnically diverse cystic fibrosis population.
Pediatrics 1994;93(1):114-8.
1993: Carole Ober; Thomas Steck; Katrin van der Ven; C Billstrand; L Messer; J Kwak; Kenneth Beaman; Alan E Beer
MHC class II compatibility in aborted fetuses and term infants of couples with recurrent spontaneous abortion.
Journal of reproductive immunology 1993;25(3):195-207.
1993: Carole Ober; T Karrison; L Harlow; Sherman Elias; N Gleicher
Autoantibodies and pregnancy history in a healthy population.
American journal of obstetrics and gynecology 1993;169(1):143-7.
1993: DD Kostyu; Deborah V Dawson; S Elias; Carole Ober
Deficit of HLA homozygotes in a Caucasian isolate.
Human immunology 1993;37(3):135-42.
1993: Marion S Verp; M Sibul; C Billstrand; G Bellen; M Hsu; Carole Ober
Maternal-fetal histocompatibility in intrauterine growth retarded and normal weight babies.
American journal of reproductive immunology (New York, N.Y. : 1989) 1993;29(4):195-8.
1992: Carole Ober; S Weil; Thomas Steck; C Billstrand; S Levrant; R Barnes
Increased risk for polycystic ovary syndrome associated with human leukocyte antigen DQA1*0501.
American journal of obstetrics and gynecology 1992;167(6):1803-6.
1992: Carole Ober; L A Lester; C Mott; C Billstrand; A Lemke; Katrin van der Ven; S Marcus; J Kraut; J Lloyd-Still; C Booth
Ethnic heterogeneity and cystic fibrosis transmembrane regulator (CFTR) mutation frequencies in Chicago-area CF families.
American journal of human genetics 1992;51(6):1344-8.
1992: Marion S Verp; H H Harrison; Carole Ober; D Oliveri; A P Amarose; V Lindgren; A Talerman
Chimerism as the etiology of a 46,XX/46,XY fertile true hermaphrodite.
Fertility and sterility 1992;57(2):346-9.
1992: Carole Ober; Sherman Elias; DD Kostyu; W W Hauck
Decreased fecundability in Hutterite couples sharing HLA-DR.
American journal of human genetics 1992;50(1):6-14.
1992: Carole Ober
The maternal-fetal relationship in human pregnancy: an immunogenetic perspective.
Experimental and clinical immunogenetics 1992;9(1):1-14.
1991: H Harrison; K Miller; Carole Ober; Samuel Refetoff; M Dick; S Elias
Identification of a serum protein polymorphism via two-dimensional electrophoresis. Family and population studies in two genetically isolated groups: North American Hutterites and Australian aborigines.
American journal of human genetics 1991;48(2):362-9.
1991: W W Hauck; Carole Ober
Statistical analysis of outcomes from repeated pregnancies: effects of HLA sharing on fetal loss rates.
Genetic epidemiology 1991;8(3):187-97.
1989: DD Kostyu; Carole Ober; Deborah V Dawson; M Ghanayem; S Elias; A O Martin
Genetic analysis of HLA in the U.S. Schmiedenleut Hutterites.
American journal of human genetics 1989;45(2):261-9.
1989: Joe Simpson; CM Meyers; A O Martin; Sherman Elias; Carole Ober
Translocations are infrequent among couples having repeated spontaneous abortions but no other abnormal pregnancies.
Fertility and sterility 1989;51(5):811-4.
1989: Carole Ober; Kun-san Xiang; R A Thisted; K A Indovina; C J Wason; S Dooley
Increased risk for gestational diabetes mellitus associated with insulin receptor and insulin-like growth factor II restriction fragment length polymorphisms.
Genetic epidemiology 1989;6(5):559-69.
1988: Carole Ober; Sherman Elias; E O'Brien; DD Kostyu; W W Hauck; A Bombard
HLA sharing and fertility in Hutterite couples: evidence for prenatal selection against compatible fetuses.
American journal of reproductive immunology and microbiology : AJRIM 1988;18(4):111-5.
1987: Carole Ober; Joe Simpson; M Ward; R M Radvany; R Andersen; Sherman Elias; R Sabbagha
Prenatal effects of maternal-fetal HLA compatibility.
American journal of reproductive immunology and microbiology : AJRIM 1987;15(4):141-9.
1987: Carole Ober; A Bombard; R Dhaliwal; Sherman Elias; J Fagan; T G Laffler; A O Martin; B Rosinsky
Studies of cystic fibrosis in Hutterite families by using linked DNA probes.
American journal of human genetics 1987;41(6):1145-51.
1987: Carole Ober; C J Wason; K Andrew; S Dooley
Restriction fragment length polymorphisms of the insulin gene hypervariable region in gestational onset diabetes mellitus.
American journal of obstetrics and gynecology 1987;157(6):1364-8.
1987: Joe Simpson; James L Mills; L B Holmes; Carole Ober; JH Aarons; L Jovanovic; Robert H Knopp
Low fetal loss rates after ultrasound-proved viability in early pregnancy.
JAMA : the journal of the American Medical Association 1987;258(18):2555-7.
1987: R M Radvany; N Vaisrub; Carole Ober; K M Patel; F Hecht
The human sex ratio: increase in first-born males to parents with shared HLA-DR antigens.
Tissue antigens 1987;29(1):34-42.
1985: Carole Ober; W W Hauck; DD Kostyu; E O'Brien; Sherman Elias; Joe Simpson; A O Martin
Adverse effects of human leukocyte antigen-DR sharing on fertility: a cohort study in a human isolate.
Fertility and sterility 1985;44(2):227-32.
1983: Carole Ober; A O Martin; Joe Simpson; W W Hauck; D B Amos; DD Kostyu; M Fotino; F H Allen
Shared HLA antigens and reproductive performance among Hutterites.
American journal of human genetics 1983;35(5):994-1004.