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Markus Oberthür

Research Profile

Chemicals & Drugs

Concepts & Ideas

Phenomena

Glycosylation

Living Beings

Genes & Molecular Sequences

Molecular Structure

Procedures

Cloning, Molecular

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Publications

TOP 3
James G Taylor; Xuechen Li; Markus Oberthür; Wenjiang Zhu; Daniel Kahne
The total synthesis of moenomycin A.
Markus Oberthür; Catherine Leimkuhler; Ryan G Kruger; Wei Lu; Christopher T Walsh; Daniel Kahne
A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases.
Wei Lu; Catherine Leimkuhler; Gregory J Gatto; Ryan G Kruger; Markus Oberthür; Daniel Kahne; Christopher T Walsh
AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A.

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All Publications

2006: James G Taylor; Xuechen Li; Markus Oberthür; Wenjiang Zhu; Daniel Kahne
The total synthesis of moenomycin A.
Journal of the American Chemical Society 2006;128(47):15084-5.
2005: Markus Oberthür; Catherine Leimkuhler; Ryan G Kruger; Wei Lu; Christopher T Walsh; Daniel Kahne
A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases.
Journal of the American Chemical Society 2005;127(30):10747-52.
2005: Wei Lu; Catherine Leimkuhler; Gregory J Gatto; Ryan G Kruger; Markus Oberthür; Daniel Kahne; Christopher T Walsh
AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A.
Chemistry & biology 2005;12(5):527-34.
2005: Michelle Pacholec; CAREN MEYERS; Markus Oberthür; Daniel Kahne; Christopher T Walsh
Characterization of the aminocoumarin ligase SimL from the simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway.
Biochemistry 2005;44(12):4949-56.
2005: Catherine Leimkuhler; Lan Chen; Dianah Barrett; Gianbattista Panzone; Binyuan Sun; Brian Falcone; Markus Oberthür; Stefano Donadio; Suzanne Walker; Daniel Kahne
Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics.
Journal of the American Chemical Society 2005;127(10):3250-1.
2005: Ryan G Kruger; Wei Lu; Markus Oberthür; Junhua Tao; Daniel Kahne; Christopher T Walsh
Tailoring of glycopeptide scaffolds by the acyltransferases from the teicoplanin and A-40,926 biosynthetic operons.
Chemistry & biology 2005;12(1):131-40.
2004: CAREN MEYERS; Markus Oberthür; Lutz Heide; Daniel Kahne; Christopher T Walsh
Assembly of dimeric variants of coumermycins by tandem action of the four biosynthetic enzymes CouL, CouM, CouP, and NovN.
Biochemistry 2004;43(47):15022-36.
2004: Markus Oberthür; Catherine Leimkuhler; Daniel Kahne
A practical method for the stereoselective generation of beta-2-deoxy glycosyl phosphates.
Organic letters 2004;6(17):2873-6.
2004: Wei Lu; Catherine Leimkuhler; Markus Oberthür; Daniel Kahne; Christopher T Walsh
AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A.
Biochemistry 2004;43(15):4548-58.
2004: Wei Lu; Markus Oberthür; Catherine Leimkuhler; Junhua Tao; Daniel Kahne; Christopher T Walsh
Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4390-5.
2004: CAREN MEYERS; Markus Oberthür; Hui Xu; Lutz Heide; Daniel Kahne; Christopher T Walsh
Characterization of NovP and NovN: completion of novobiocin biosynthesis by sequential tailoring of the noviosyl ring.
Angewandte Chemie (International ed. in English) 2004;43(1):67-70.
2003: CAREN MEYERS; Markus Oberthür; John W Anderson; Daniel Kahne; Christopher T Walsh
Initial characterization of novobiocic acid noviosyl transferase activity of NovM in biosynthesis of the antibiotic novobiocin.
Biochemistry 2003;42(14):4179-89.
2002: Heather C Losey; Jiqing Jiang; John B Biggins; Markus Oberthür; Xiang Yang Ye; Steven D Dong; Daniel Kahne; Jon S Thorson; Christopher T Walsh
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides.
Chemistry & biology 2002;9(12):1305-14.
2002: Steven D Dong; Markus Oberthür; Heather C Losey; John W Anderson; Ulrike S Eggert; Mark W Peczuh; Christopher T Walsh; Daniel Kahne
The structural basis for induction of VanB resistance.
Journal of the American Chemical Society 2002;124(31):9064-5.