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Satoshi Obika

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
69
Imanishi, Takeshi
17
Hari, Yoshiyuki
10
Torigoe, Hidetaka
9
Rahman, Abdur
9
Kodama, Tetsuya
8
Miyashita, Kazuyuki
8
Nakagawa, Osamu
8
Sekiguchi, Mitsuaki
7
Seki, Sayori
7
Osaki, Tomohisa
5
Mitsuoka, Yasunori
5
Doi, Takefumi
5
Inohara, Hidenori
5
Hiroto, Akiko
5
Uneda, Tomomi

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Publications

TOP 3
Morihiro Kunihiko; Kodama Tetsuya; Nishida Masaru; Imanishi Takeshi; Obika Satoshi
Synthesis of light-responsive bridged nucleic acid and changes in affinity with complementary ssRNA.
Nakahara Motoi; Kuboyama Takeshi; Izawa Akihiro; Hari Yoshiyuki; Imanishi Takeshi; Obika Satoshi
Synthesis and base-pairing properties of C-nucleotides having 1-substituted 1H-1,2,3-triazoles.
Torigoe Hidetaka; Maruyama Atushi; Obika Satoshi; Imanishi Takeshi; Katayama Takuma
Synergistic stabilization of nucleic acid assembly by 2'-O,4'-C-methylene-bridged nucleic acid modification and additions of comb-type cationic copolymers.

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All Publications

2009: Morihiro Kunihiko; Kodama Tetsuya; Nishida Masaru; Imanishi Takeshi; Obika Satoshi
Synthesis of light-responsive bridged nucleic acid and changes in affinity with complementary ssRNA.
Chembiochem : a European journal of chemical biology 2009;10(11):1784-8.
2009: Nakahara Motoi; Kuboyama Takeshi; Izawa Akihiro; Hari Yoshiyuki; Imanishi Takeshi; Obika Satoshi
Synthesis and base-pairing properties of C-nucleotides having 1-substituted 1H-1,2,3-triazoles.
Bioorganic & medicinal chemistry letters 2009;19(12):3316-9.
2009: Torigoe Hidetaka; Maruyama Atushi; Obika Satoshi; Imanishi Takeshi; Katayama Takuma
Synergistic stabilization of nucleic acid assembly by 2'-O,4'-C-methylene-bridged nucleic acid modification and additions of comb-type cationic copolymers.
Biochemistry 2009;48(15):3545-53.
2009: Mitsuoka Yasunori; Kodama Tetsuya; Ohnishi Ryo; Hari Yoshiyuki; Imanishi Takeshi; Obika Satoshi
A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognition.
Nucleic acids research 2009;37(4):1225-38.
2009: Morihiro Kunihiko; Kodama Tetsuya; Nishida Masaru; Imanishi Takeshi; Obika Satoshi
Development of light-responsive BNA toward the spatiotemporal control of gene expression.
Nucleic acids symposium series (2004) 2009;(53):187-8.
2009: Sasaki Kiyomi; Rahman S M Abdur; Sato Norihiro; Obika Satoshi; Imanishi Takeshi; Torigoe Hidetaka
Promotion of triplex formation by 3'-amino-2'-O,4'-C-methylene bridged nucleic acid modification.
Nucleic acids symposium series (2004) 2009;(53):159-60.
2009: Baba Takeshi; Kodama Tetsuya; Imanishi Takeshi; Obika Satoshi
Synthesis and properties of a novel artificial nucleoside that acts as a redox switch.
Nucleic acids symposium series (2004) 2009;(53):107-8.
2009: Yahara Aiko; Nishida Masaru; Baba Takeshi; Kodama Tetsuya; Imanishi Takeshi; Obika Satoshi
Synthesis and properties of a novel 2',4'-BNA bearing a urea bridged structure.
Nucleic acids symposium series (2004) 2009;(53):11-2.
2008: Obika Satoshi; Rahman S M Abdur; Song Bingbing; Onoda Mayumi; Koizumi Makoto; Morita Koji; Imanishi Takeshi
Synthesis and properties of 3'-amino-2',4'-BNA, a bridged nucleic acid with a N3'-->P5' phosphoramidate linkage.
Bioorganic & medicinal chemistry 2008;16(20):9230-7.
2008: Rahman S M Abdur; Seki Sayori; Obika Satoshi; Yoshikawa Haruhisa; Miyashita Kazuyuki; Imanishi Takeshi
Design, synthesis, and properties of 2',4'-BNA(NC): a bridged nucleic acid analogue.
Journal of the American Chemical Society 2008;130(14):4886-96.
2008: Obika Satoshi; Inohara Hiroyasu; Hari Yoshiyuki; Imanishi Takeshi
Recognition of T.A interruption by 2',4'-BNAs bearing heteroaromatic nucleobases through parallel motif triplex formation.
Bioorganic & medicinal chemistry 2008;16(6):2945-54.
2008: Sasaki Kiyomi; Rahman S M Abdur; Obika Satoshi; Imanishi Takeshi; Torigoe Hidetaka
Promotion of triplex formation by 2'-O,4'-C-aminomethylene bridged nucleic acid (2',4'-BNA NC) modification.
Nucleic acids symposium series (2004) 2008;(52):419-20.
2008: Miyoshi Tetsuya; Kodama Tetsuya; Obika Satoshi; Imanishi Takeshi
Design and chemical synthesis of a 2',4'-BNA probe for 7,8-dihydro-8-oxoguanine-containing double stranded DNA.
Nucleic acids symposium series (2004) 2008;(52):305-6.
2007: Obika Satoshi; Tomizu Masaharu; Negoro Yoshinori; Orita Ayako; Nakagawa Osamu; Imanishi Takeshi
Double-stranded DNA-templated oligonucleotide digestion triggered by triplex formation.
Chembiochem : a European journal of chemical biology 2007;8(16):1924-8.
2007: Miyashita Kazuyuki; Rahman S M Abdur; Seki Sayori; Obika Satoshi; Imanishi Takeshi
N-Methyl substituted 2',4'- BNANC: a highly nuclease-resistant nucleic acid analogue with high-affinity RNA selective hybridization.
Chemical communications (Cambridge, England) 2007;(36):3765-7.
2007: Rahman S M Abdur; Seki Sayori; Utsuki Kazushige; Obika Satoshi; Miyashita Kazuyuki; Imanishi Takeshi
2',4'-BNA(NC): a novel bridged nucleic acid analogue with excellent hybridizing and nuclease resistance profiles.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1625-8.
2007: Osaki Tomohisa; Obika Satoshi; Harada Yasuki; Mitsuoka Yasunori; Sugaya Kensaku; Sekiguchi Mitsuaki; Roongjang Somjing; Imanishi Takeshi
Synthesis of novel 2'-deoxy type trans-3',4'-bridged nucleic acid.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):1079-82.
2007: Obika Satoshi; Tomizu Masaharu; Negoro Yoshinori; Osaki Tomohisa; Orita Ayako; Ueyama Yuji; Nakagawa Osamu; Imanishi Takeshi
Acid-mediated cleavage of oligonucleotide P3' --> N5' phosphoramidates triggered by sequence-specific triplex formation.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):893-6.
2007: Tachibana Keisuke; Katayama Tatsuya; Ueda Chihiro; Sumitomo Mikako; Tagami Masayuki; Ishimoto Kenji; Yamasaki Daisuke; Tanaka Toshiya; Hamakubo Takao; Sakai Juro; Kodama Tatsuhiko; Obika Satoshi; Imanishi Takeshi; Doi Takefumi
Antisense activity of 2',4'-BNA targeted to PPAR gamma in THP-1 and HCT116 cells.
Nucleic acids symposium series (2004) 2007;(51):441-2.
2007: Kodama Tetsuya; Matsuo Chieko; Ori Hidetsugu; Obika Satoshi; Miyashita Kazuyuki; Imanishi Takeshi
Synthesis and evaluation of a novel 2',5'-bridged nucleic acid with sugar conformation fixed to S-type by N-O linkage.
Nucleic acids symposium series (2004) 2007;(51):159-60.
2007: Nishida Masaru; Kodama Tetsuya; Obika Satoshi; Imanishi Takeshi
Synthesis and chemical properties of a novel 2',4'-bridged nucleic acid analogue with a seven-membered cyclic carbamate structure.
Nucleic acids symposium series (2004) 2007;(51):157-8.
2007: Sugaya Kensaku; Harada Yasuki; Mitsuoka Yasunori; Osaki Tomohisa; Obika Satoshi; Kodama Tetsuya; Imanishi Takeshi
Synthesis and properties of a 2'-deoxy analogue of trans-3',4'-BNA with an S-type sugar conformation.
Nucleic acids symposium series (2004) 2007;(51):155-6.
2007: Roongjang Somjing; Takahashi Kurena; Obika Satoshi; Imanishi Takeshi
Inhibition of bcl-xL expression by antisense oligonucleotides containing various bridged nucleic acids (BNAs).
Nucleic acids symposium series (2004) 2007;(51):113-4.
2007: Rahman S M Abdur; Seki Sayori; Obika Satoshi; Haitani Sunao; Miyashita Kazuyuki; Imanishi Takeshi
Highly stable pyrimidine-motif triplex formation at physiological pH values by a bridged nucleic acid analogue.
Angewandte Chemie (International ed. in English) 2007;46(23):4306-9.
2006: Sekiguchi Mitsuaki; Obika Satoshi; Harada Yasuki; Osaki Tomohisa; Somjing Roongjang; Mitsuoka Yasunori; Shibata Nao; Masaki Miyuki; Imanishi Takeshi
Synthesis and properties of trans-3',4'-bridged nucleic acids having typical S-type sugar conformation.
The Journal of organic chemistry 2006;71(4):1306-16.
2006: Hari Yoshiyuki; Obika Satoshi; Ohnishi Ryo; Eguchi Ken; Osaki Tomohisa; Ohishi Hirofumi; Imanishi Takeshi
Synthesis and properties of 2'-O,4'-C-methyleneoxymethylene bridged nucleic acid.
Bioorganic & medicinal chemistry 2006;14(4):1029-38.
2006: Roongjang Somjing; Takahashi Kurena; Park Myunji; Obika Satoshi; Imanishi Takeshi
Antisense activity of 2',4'-BNA targeted to bcl-xL gene in HepG2 cell.
Nucleic acids symposium series (2004) 2006;(50):289-90.
2006: Rahman S M Abdur; Seki Sayori; Utsuki Kazushige; Obika Satoshi; Miyashita Kazuyuki; Imanishi Takeshi
High-affinity RNA mimicking binding of 2',4'-BNANC towards complementary strands: a comparative study with 2',4'-BNA/LNA.
Nucleic acids symposium series (2004) 2006;(50):195-6.
2006: Mitsuoka Yasunori; Ohnishi Ryo; Hari Yoshiyuki; Obika Satoshi; Imanishi Takeshi
Synthesis of 2',4'-BNACOC bearing a purine nucleobase.
Nucleic acids symposium series (2004) 2006;(50):13-4.
2005: Hari Yoshiyuki; Obika Satoshi; Inohara Hiroyasu; Ikejiri Masahiro; Une Daisuke; Imanishi Takeshi
Synthesis and triplex-forming ability of 2',4'-BNAs bearing imidazoles as a nucleobase.
Chemical & pharmaceutical bulletin 2005;53(7):843-6.
2005: Obika Satoshi; Hiroto Akiko; Nakagawa Osamu; Imanishi Takeshi
Promotion of stable triplex formation by partial incorporation of 2',5'-phosphodiester linkages into triplex-forming oligonucleotides.
Chemical communications (Cambridge, England) 2005;(22):2793-5.
2005: Obika Satoshi; Sekiguchi Mitsuaki; Somjing Roongjang; Imanishi Takeshi
Adjustment of the gamma dihedral angle of an oligonucleotide P3'-->N5' phosphoramidate enhances its binding affinity towards complementary strands.
Angewandte Chemie (International ed. in English) 2005;44(13):1944-7.
2005: Tsuda Naoto; Matsumoto Ayumi; Ito Aya; Uneda Tomomi; Tanabe Atsuhiro; Obika Satoshi; Imanishi Takeshi
Antigene-block strategy: effective regulation of gene expression by 2',4'-BNA-modified TFOs with an additional stem-loop structure.
Nucleic acids symposium series (2004) 2005;(49):335-6.
2005: Fujii Shiho; Obika Satoshi; Imanishi Takeshi
Effects of the 2',4'-BNA modification on the sequence specificity of molecular beacons.
Nucleic acids symposium series (2004) 2005;(49):211-2.
2005: Matsugu Sachiko; Inohara Hiroyasu; Obika Satoshi; Imanishi Takeshi
Synthesis and triplex-forming properties of 2',4'-BNA derivatives bearing pyridines as an unnatural nucleobase.
Nucleic acids symposium series (2004) 2005;(49):159-60.
2005: Tomizu Masaharu; Nakagawa Osamu; Obika Satoshi; Imanishi Takeshi
Promotion of acid-mediated cleavage of oligonucleotide P3'->N5' phosphoroamidates by triplex formation: a novel approach to sequence-specific DNA detection.
Nucleic acids symposium series (2004) 2005;(49):157-8.
2005: Rahman S M Abdur; Seki Sayori; Utsuki Kazushige; Obika Satoshi; Miyashita Kazuyuki; Imanishi Takeshi
Synthesis and properties of 2',4'-BNA(NC), a second generation BNA.
Nucleic acids symposium series (2004) 2005;(49):5-6.
2005: Sekiguchi Mitsuaki; Obika Satoshi; Somjing Roongjang; Imanishi Takeshi
Synthesis and properties of a novel bridged nucleic acid analogue, 5'-amino-3',5'-BNA.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):1097-100.
2005: Obika Satoshi; Hiroto Akiko; Nakagawa Osamu; Imanishi Takeshi
Presence of 2',5'-linkages in a homopyrimidine DNA oligonucleotide promotes stable triplex formation under physiological conditions.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):1055-8.
2005: Torigoe Hidetaka; Katayama Takuma; Obika Satoshi; Maruyama Atushi; Imanishi Takeshi
Combination of poly(L-lysine)-graft-dextran copolymer and 2'-O,4'-C-methylene bridged nucleic acid (2',4'-BNA) modification synergistically stabilizes pyrimidine motif triplex at neutral pH.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):635-8.
2004: Obika Satoshi
Development of bridged nucleic acid analogues for antigene technology.
Chemical & pharmaceutical bulletin 2004;52(12):1399-404.
2004: Obika Satoshi
[Bridged nucleic acids (BNAs) as a basic material for genome technology]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2004;124(11):781-90.
2004: Katayama Takuma; Maruyama Atsushi; Obika Satoshi; Imanishi Takeshi; Torigoe Hidetaka
Synergistic stabilization of triplex by combination of comb-type cationic copolymer and 2',4'-BNA.
Nucleic acids symposium series (2004) 2004;(48):139-40.
2004: Inohara Hiroyasu; Obika Satoshi; Imanishi Takeshi
2',4'-BNA derivatives bearing an unnatural nucleobase: synthesis and application to triplex-forming oligonucleotides.
Nucleic acids symposium series (2004) 2004;(48):63-4.
2004: Sekiguchi Mitsuaki; Obika Satoshi; Somjing Roonjang; Imanishi Takeshi
Synthesis and properties of a novel bridged nucleic acid analogue bearing a P3'-->N5' phosphoroamidate linkage, 5'-amino-3', 5'-BNA.
Nucleic acids symposium series (2004) 2004;(48):7-8.
2003: Obika Satoshi; Nakagawa Osamu; Hiroto Akiko; Hari Yoshiyuki; Imanishi Takeshi
Synthesis and properties of a novel bridged nucleic acid with a P3' --> N5' phosphoramidate linkage, 5'-amino-2',4'-BNA.
Chemical communications (Cambridge, England) 2003;(17):2202-3.
2003: Torigoe Hidetaka; Hari Yoshiyuki; Obika Satoshi; Imanishi Takeshi
Triplex formation involving 2'-O,4'-C-methylene bridged nucleic acid (2',4'-BNA) with 1-isoquinolone base analogue: efficient and selective recognition of C:G interruption.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1571-3.
2003: Torigoe Hidetaka; Hari Yoshiyuki; Obika Satoshi; Imanishi Takeshi
Triplex formation involving 2'-O,4'-C-methylene bridged nucleic acid (2',4'-BNA) with 2-pyridone base analogue: efficient and selective recognition of C:G interruption.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1097-9.
2003: Gao Ping; Zhou Xu-Yu; Yashiro-Ohtani Yumi; Yang Yi-Fu; Sugimoto Naotoshi; Ono Shiro; Nakanishi Tsuyoshi; Obika Satoshi; Imanishi Takeshi; Egawa Takeshi; Nagasawa Takashi; Fujiwara Hiromi; Hamaoka Toshiyuki
The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3.
Journal of leukocyte biology 2003;73(2):273-80.
2003: Sekiguchi Mitsuaki; Osaki Tomohisa; Harada Yasuki; Obika Satoshi; Imanishi Takeshi
trans-3',4'-BNAs, novel nucleic acid analogues with an S-type conformation: synthesis and incorporation into oligonucleotides.
Nucleic acids research. Supplement (2001) 2003;(3):111-2.
2003: Nakagawa Osamu; Hiroto Akiko; Obika Satoshi; Imanishi Takeshi
A novel nucleic acid analogue, 3'-amino-2'-deoxy-3',4'-BNA, with an N3'-->P5' phosphoramidate linkage and an S-type conformation.
Nucleic acids research. Supplement (2001) 2003;(3):87-8.
2002: Obika Satoshi; Hari Yoshiyuki; Sekiguchi Mitsuaki; Imanishi Takeshi
Stable oligonucleotide-directed triplex formation at target sites with CG interruptions: strong sequence-specific recognition by 2',4'-bridged nucleic-acid-containing 2-pyridones under physiological conditions.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(20):4796-802.
2002: Yang Yi-Fu; Mukai Takao; Gao Ping; Yamaguchi Nobuya; Ono Shiro; Iwaki Hiroshi; Obika Satoshi; Imanishi Takeshi; Tsujimura Takahiro; Hamaoka Toshiyuki; Fujiwara Hiromi
A non-peptide CCR5 antagonist inhibits collagen-induced arthritis by modulating T cell migration without affecting anti-collagen T cell responses.
European journal of immunology 2002;32(8):2124-32.
2002: Imanishi Takeshi; Obika Satoshi
BNAs: novel nucleic acid analogs with a bridged sugar moiety.
Chemical communications (Cambridge, England) 2002;(16):1653-9.
2002: Imanishi Takeshi; Obika Satoshi
[Down-regulation of a gene-expression by an antisense BNA oligonucleotide]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 2002;120(2):85-90.
2002: Uekusa Yasuhiro; Yu Wen-Gong; Mukai Takao; Gao Ping; Yamaguchi Nobuya; Murai Masako; Matsushima Kouji; Obika Satoshi; Imanishi Takeshi; Higashibata Yuji; Nomura Shintaro; Kitamura Yukihiko; Fujiwara Hiromi; Hamaoka Toshiyuki
A pivotal role for CC chemokine receptor 5 in T-cell migration to tumor sites induced by interleukin 12 treatment in tumor-bearing mice.
Cancer research 2002;62(13):3751-8.
2002: Miyashita Kazuyuki; Park Myunji; Adachi Sayako; Seki Sayori; Obika Satoshi; Imanishi Takeshi
A 3,4-epoxypiperidine structure as a novel and simple DNA-cleavage unit.
Bioorganic & medicinal chemistry letters 2002;12(7):1075-7.
2002: Torigoe Hidetaka; Hari Yoshiyuki; Obika Satoshi; Imanishi Takeshi
Triplex formation involving 2',4'-BNA with isoquinolone base analogue: efficient and selective recognition of C:G interruption.
Nucleic acids research. Supplement (2001) 2002;(2):183-4.
2002: Hari Yoshiyuki; Osaki Tomohisa; Eguchi Ken; Obika Satoshi; Imanishi Takeshi
Synthesis and properties of oligonucleotides containing novel 2',4'-BNA analogues (2',4'-BNACOC).
Nucleic acids research. Supplement (2001) 2002;(2):147-8.
2002: Torigoe Hidetaka; Sato Shinobu; Yamashita Ken-ichi; Obika Satoshi; Imanishi Takeshi; Takenaka Shigeori
Binding of threading intercalator to nucleic acids: thermodynamic analyses.
Nucleic acids research. Supplement (2001) 2002;(2):55-6.
2002: Obika Satoshi; Nakagawa Osamu; Hiroto Akiko; Hari Yoshiyuki; Imanishi Takeshi
Synthesis and properties of 5'-amino-2',4'-BNA modified oligonucleotides with P3'-->N5' phosphoramidate linkages.
Nucleic acids research. Supplement (2001) 2002;(2):25-6.
2001: Obika S; Onoda M; Morita K; Andoh J; Koizumi M; Imanishi T
3'-amino-2',4'-BNA: novel bridged nucleic acids having an N3'-->P5' phosphoramidate linkage.
Chemical communications (Cambridge, England) 2001;(19):1992-3.
2001: Obika S; Uneda T; Sugimoto T; Nanbu D; Minami T; Doi T; Imanishi T
2'-O,4'-C-Methylene bridged nucleic acid (2',4'-BNA): synthesis and triplex-forming properties.
Bioorganic & medicinal chemistry 2001;9(4):1001-11.
2001: Obika S; Yu W; Shimoyama A; Uneda T; Miyashita K; Doi T; Imanishi T
Symmetrical cationic triglycerides: an efficient synthesis and application to gene transfer.
Bioorganic & medicinal chemistry 2001;9(2):245-54.
2001: Torigoe H; Hari Y; Obika S; Imanishi T
Triplex formation involving 2',4'-BNA with 2-pyridone base analogue: efficient and selective recognition of C:G interruption.
Nucleic acids research. Supplement (2001) 2001;(1):281-2.
2001: Obika S; Hari Y; Inohara H; Imanishi T
2',4'-BNA bearing unnatural nucleobases: toward the expansion of the target sequence of double-stranded DNA in triplex formation.
Nucleic acids research. Supplement (2001) 2001;(1):171-2.
2001: Obika S; Hemamayi R; Masuda T; Sugimoto T; Nakagawa S; Mayumi T; Imanishi T
Inhibition of ICAM-1 gene expression by antisense 2',4'-BNA oligonucleotides.
Nucleic acids research. Supplement (2001) 2001;(1):145-6.
2000: Obika S
[Syntheses and properties of conformationally restrained nucleosides and oligonucleotides analogues]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2000;120(2):147-58.
2000: Obika S; Hari Y; Sekiguchi M; Imanishi T
Synthesis and triplex forming ability of conformationally locked oligonucleotides containing unnatural nucleobases: efficient recognition of a C.G interruption.
Nucleic acids symposium series 2000;(44):131-2.
1999: Yu W; Shimoyama A; Uneda T; Obika S; Miyashita K; Doi T; Imanishi T
Gene transfer mediated by YKS-220 cationic particles: convenient and efficient gene delivery reagent.
Journal of biochemistry 1999;125(6):1034-8.
1999: Obika S; Morio K; Hari Y; Imanishi T
Preparation and properties of 2',5'-linked oligonucleotide analogues containing 3'-O,4'-C-methyleneribonucleosides.
Bioorganic & medicinal chemistry letters 1999;9(4):515-8.
1999: Obika S; Yu W; Shimoyama A; Uneda T; Minami T; Miyashita K; Doi T; Imanishi T
Properties of cationic liposomes composed of cationic lipid YKS-220 having an ester linkage: adequate stability, high transfection efficiency, and low cytotoxicity.
Biological & pharmaceutical bulletin 1999;22(2):187-90.

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