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Mavis Agbandje-McKenna

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Lawrence J Tartaglia; Andrew G Woodhouse; Fikret Aydemir; Antonette Bennett; Nicholas Muzyczka; Mavis Agbandje-McKenna
Construction, expression, and purification of recombinant αVβ5 integrin.
Sujata Halder; Robert McKenna; Hyun-Joo Nam; Nathalie Salomé; Michèle Vogel; Christiane Dinsart; Lakshmanan Govindasamy; Mavis Agbandje-McKenna
Structural characterization of H-1 parvovirus: comparison of infectious virions to empty capsids.
Balasubramanian Venkatakrishnan; Joseph Yarbrough; Antonette Bennett; Brian Bothner; John Domsic; Olga G Kozyreva; Robert McKenna; Nicholas Muzyczka; R Jude Samulski; Mavis Agbandje-McKenna
Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking.

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2013: Lawrence J Tartaglia; Andrew G Woodhouse; Fikret Aydemir; Antonette Bennett; Nicholas Muzyczka; Mavis Agbandje-McKenna
Construction, expression, and purification of recombinant αVβ5 integrin.
Protein expression and purification 2013;89(2):225-31.
2013: Sujata Halder; Robert McKenna; Hyun-Joo Nam; Nathalie Salomé; Michèle Vogel; Christiane Dinsart; Lakshmanan Govindasamy; Mavis Agbandje-McKenna
Structural characterization of H-1 parvovirus: comparison of infectious virions to empty capsids.
Journal of virology 2013;87(9):5128-40.
2013: Balasubramanian Venkatakrishnan; Joseph Yarbrough; Antonette Bennett; Brian Bothner; John Domsic; Olga G Kozyreva; Robert McKenna; Nicholas Muzyczka; R Jude Samulski; Mavis Agbandje-McKenna
Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking.
Journal of virology 2013;87(9):4974-84.
2013: Christine N Kay; Seok-Hong Min; Qing Ruan; Renee C Ryals; Jingfen Sun; Kim Van Vliet; Mavis Agbandje-McKenna; George Aslanidi; Andrea E Ayala; Sanford L Boye; Frank M Dyka; William W Hauswirth; Daniel Kasuga; Shannon E Boye
Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors.
PloS one 2013;8(4):e62097.
2013: George Aslanidi; Lakshmanan Govindasamy; Chen Ling; Luis Ortiz; Angela E Rivers; Liujiang Song; Mengqun Tan; Kim Van Vliet; Mavis Agbandje-McKenna; Arun Srivastava
Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?
PloS one 2013;8(3):e59142.
2012: Ying Yu; Xuezheng Song; David A Steinhauer; Mary M Tappert; Peter Tattersall; Mavis Agbandje-McKenna; Gillian M Air; Konrad C Bradley; Susan Cotmore; Richard D Cummings; Sujata Halder; Yi Lasanajak; Shreya Mishra; David F Smith
Functional glycomic analysis of human milk glycans reveals the presence of virus receptors and embryonic stem cell biomarkers.
The Journal of biological chemistry 2012;287(53):44784-99.
2012: Sujata Halder; Robert McKenna; Hyun-Joo Nam; Nathalie Salomé; Michèle Vogel; Christiane Dinsart; Lakshmanan Govindasamy; Mavis Agbandje-McKenna
Production, purification, crystallization and structure determination of H-1 Parvovirus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 12):1571-6.
2012: Maxim Salganik; Balasubramanian Venkatakrishnan; Joseph Yarbrough; Nicholas Muzyczka; Mavis Agbandje-McKenna; Antonette Bennett; Bridget Lins; Robert McKenna
Evidence for pH-dependent protease activity in the adeno-associated virus capsid.
Journal of virology 2012;86(21):11877-85.
2012: Christina Raupp; Mavis Agbandje-McKenna; Brittney L Gurda; Oliver J Müller; Matthias Naumer; Jürgen A Kleinschmidt
The threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing.
Journal of virology 2012;86(17):9396-408.
2012: Chengwen Li; Paul E Monahan; Joseph Rabinowitz; Mavis Agbandje-McKenna; Aravind Asokan; Dawn E Bowles; Nina Diprimio; Matthew L Hirsch; R Jude Samulski
Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles.
Journal of virology 2012;86(15):7752-9.
2012: Brittney L Gurda; Jürgen A Kleinschmidt; Robert McKenna; Matthias Naumer; Robert Ng; Norman H Olson; Ruth Popa-Wagner; Christina Raupp; Timothy S Baker; Mavis Agbandje-McKenna
Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8.
Journal of virology 2012;86(15):7739-51.
2012: Zoë Fisher; David Silverman; Chingkuang Tu; Balasubramanian Venkatakrishnan; Mavis Agbandje-McKenna; Mayank Aggarwal; Shya Masri Biswas; Christopher D Boone; Robert McKenna
Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein engineering, design & selection : PEDS 2012;25(7):347-55.
2012: Christie L Bell; Brittney L Gurda; Kim Van Vliet; Mavis Agbandje-McKenna; James M Wilson
Identification of the galactose binding domain of the adeno-associated virus serotype 9 capsid.
Journal of virology 2012;86(13):7326-33.
2012: George Aslanidi; Lakshmanan Govindasamy; Giridhara R Jayandharan; Chen Ling; Luis Ortiz; Angela E Rivers; Mavis Agbandje-McKenna; Sergei Zolotukhin; Arun Srivastava
High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors.
Vaccine 2012;30(26):3908-17.
2012: Michael A DiMattia; Brittney L Gurda; Robert McKenna; Matthew Mitchell; Nicholas Muzyczka; Hyun-Joo Nam; Norman H Olson; Mark Potter; Robert S Sinkovits; Kim Van Vliet; Sergei Zolotukhin; George Aslanidi; Timothy S Baker; Antonette Bennett; Barry J Byrne; Mavis Agbandje-McKenna
Structural insight into the unique properties of adeno-associated virus serotype 9.
Journal of virology 2012;86(12):6947-58.
2012: Balasubramanian Venkatakrishnan; Miorel-Lucian Palii; Mavis Agbandje-McKenna; Robert McKenna
Mining the protein data bank to differentiate error from structural variation in clustered static structures: an examination of HIV protease.
Viruses 2012;4(3):348-62.
2012: Carole E Harbison; Mavis Agbandje-McKenna; John A Chiorini; Brittney L Gurda; Wendy S Weichert; Colin R Parrish
Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5.
The Journal of general virology 2012;93(Pt 2):347-55.
2012: Dawn E Bowles; Angelique S Camp; Lakshmanan Govindasamy; Steven J Gray; Joshua C Grieger; Chengwen Li; Juan Li; Scott W J McPhee; Paul E Monahan; Joseph E Rabinowitz; Jade J Samulski; Bing Wang; Xiao Xiao; Mavis Agbandje-McKenna; R Jude Samulski
Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(2):443-55.
2012: Justin Judd; Peter Q Nguyen; Jonathan J Silberg; Lawrence J Tartaglia; Fang Wei; Mavis Agbandje-McKenna; Junghae Suh
Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity.
Molecular therapy. Nucleic acids 2012;1():e54.
2011: Hyun-Joo Nam; Mark Potter; Maxim Salganik; Barry Byrne; Brittney L Gurda; Robert McKenna; Nicholas Muzyczka; Mavis Agbandje-McKenna
Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
Journal of virology 2011;85(22):11791-9.
2011: Mavis Agbandje-McKenna; Richard Kuhn
Current opinion in virology: structural virology.
Current opinion in virology 2011;1(2):81-3.
2011: Christie L Bell; Luk H Vandenberghe; Peter Bell; Maria P Limberis; Guang-Ping Gao; Kim Van Vliet; Mavis Agbandje-McKenna; James M Wilson
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice.
The Journal of clinical investigation 2011;121(6):2427-35.
2011: Nagesh Pulicherla; Shen Shen; Swati Yadav; Kari Debbink; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Aravind Asokan
Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(6):1070-8.
2011: Katherine H Sippel; Balasubramanian Venkatakrishnan; Susan K Boehlein; Banumathi Sankaran; Jeanne G Quirit; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Steve Goodison; Charles J Rosser; Robert McKenna
Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins 2011;79(2):528-36.
2011: Hilda Petrs-Silva; Astra Dinculescu; Qiuhong Li; Wen-Tao Deng; Ji-Jing Pang; Seok-Hong Min; Vince A Chiodo; Andy W Neeley; Lakshmanan Govindasamy; Antonette Bennett; Mavis Agbandje-McKenna; Li Zhong; Baozheng Li; Giridhara R Jayandharan; Arun Srivastava; Alfred S Lewin; William W Hauswirth
Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(2):293-301.
2011: Mavis Agbandje-McKenna; Jürgen Kleinschmidt
AAV capsid structure and cell interactions.
Methods in molecular biology (Clifton, N.J.) 2011;807():47-92.
2010: Robert Ng; Lakshmanan Govindasamy; Brittney L Gurda; Robert McKenna; Olga G Kozyreva; R Jude Samulski; Kristin N Parent; Timothy S Baker; Mavis Agbandje-McKenna
Structural characterization of the dual glycan binding adeno-associated virus serotype 6.
Journal of virology 2010;84(24):12945-57.
2010: Chen Ling; Yuan Lu; Jasmine K Kalsi; Giridhara R Jayandharan; Baozheng Li; Wenqin Ma; Binbin Cheng; Samantha W Y Gee; Katherine E McGoogan; Lakshmanan Govindasamy; Li Zhong; Mavis Agbandje-McKenna; Arun Srivastava
Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3.
Human gene therapy 2010;21(12):1741-7.
2010: Anurima Majumder; Lakshmanan Govindasamy; Andrew Magis; Róbert Kiss; Tímea Polgár; Rebekah Baskin; Robert W Allan; Mavis Agbandje-McKenna; Gary W Reuther; György M Keseru; Kirpal S Bisht; Peter P Sayeski
Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core.
The Journal of biological chemistry 2010;285(41):31399-407.
2010: John F Domsic; Wilton Williams; S Zoë Fisher; Chingkuang Tu; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Structural and kinetic study of the extended active site for proton transfer in human carbonic anhydrase II.
Biochemistry 2010;49(30):6394-9.
2010: Arthur H Robbins; John F Domsic; Mavis Agbandje-McKenna; Robert McKenna
Emerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinic P2(1) with a doubled a axis.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 8):950-2.
2010: Brittney L Gurda; Kristin N Parent; Heather Bladek; Robert S Sinkovits; Michael A DiMattia; Chelsea Rence; Alejandro Castro; Robert McKenna; Norm Olson; Kevin Brown; Timothy S Baker; Mavis Agbandje-McKenna
Human bocavirus capsid structure: insights into the structural repertoire of the parvoviridae.
Journal of virology 2010;84(12):5880-9.
2010: Arthur H Robbins; John F Domsic; Mavis Agbandje-McKenna; Robert McKenna
Structure of a monoclinic polymorph of human carbonic anhydrase II with a doubled a axis.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 5):628-34.
2010: Arthur H Robbins; Roxana M Coman; Edith Bracho-Sanchez; Marty A Fernandez; C Taylor Gilliland; Mi Li; Mavis Agbandje-McKenna; Alexander Wlodawer; Ben M Dunn; Robert McKenna
Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 3):233-42.
2010: Balendu Sankara Avvaru; Chae Un Kim; Katherine H Sippel; Sol M Gruner; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
A short, strong hydrogen bond in the active site of human carbonic anhydrase II.
Biochemistry 2010;49(2):249-51.
2010: Giovanni Di Pasquale; Nikola Kaludov; Mavis Agbandje-McKenna; John A Chiorini
BAAV transcytosis requires an interaction with beta-1-4 linked- glucosamine and gp96.
PloS one 2010;5(3):e9336.
2010: Matthew L Hirsch; Mavis Agbandje-McKenna; R Jude Samulski
Little vector, big gene transduction: fragmented genome reassembly of adeno-associated virus.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(1):6-8.
2010: Aravind Asokan; Julia C Conway; Jana L Phillips; Chengwen Li; Julia Hegge; Rebecca Sinnott; Swati Yadav; Nina DiPrimio; Hyun-Joo Nam; Mavis Agbandje-McKenna; Scott McPhee; Jon Wolff; R Jude Samulski
Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle.
Nature biotechnology 2010;28(1):79-82.
2009: Luk Vandenberghe; E Breous; H-J Nam; Guangping Gao; R Xiao; A Sandhu; Julie Johnston; zeger debyser; Mavis Agbandje-McKenna; James M Wilson
Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints.
Gene therapy 2009;16(12):1416-28.
2009: Wuping Li; Liqun Zhang; Jarrod S Johnson; Wu Zhijian; Joshua C Grieger; Xiao Ping-Jie; Lauren M Drouin; Mavis Agbandje-McKenna; Raymond J Pickles; R Jude Samulski
Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(12):2067-77.
2009: Katherine H Sippel; Arthur H Robbins; John Domsic; Caroli Genis; Mavis Agbandje-McKenna; Robert McKenna
High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 10):992-5.
2009: Katherine H Sippel; Susan K Boehlein; Yoshihisa Sakai; Jeanne G Quirit; Mavis Agbandje-McKenna; Charles J Rosser; Robert McKenna
Cloning, expression, purification, crystallization and preliminary X-ray analysis of Mycoplasma genitalium protein MG289.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 9):910-2.
2009: Balendu Sankara Avvaru; Scott A Busby; Michael J Chalmers; Patrick R Griffin; Balasubramanian Venkatakrishnan; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network.
Biochemistry 2009;48(31):7365-72.
2009: Kim Van Vliet; Yasmin Mohiuddin; Scott McClung; Veronique Blouin; Fabienne Rolling; Philippe Moullier; Mavis Agbandje-McKenna; Richard O Snyder
Adeno-associated virus capsid serotype identification: Analytical methods development and application.
Journal of virological methods 2009;159(2):167-77.
2009: Matthew Mitchell; Hyun-Joo Nam; Adam Carter; Angela McCall; Chelsea Rence; Antonette Bennett; Brittney Gurda; Robert McKenna; Mark Porter; Yoshihisa Sakai; Barry J Byrne; Nicholas Muzyczka; George Aslanidi; Sergei Zolotukhin; Mavis Agbandje-McKenna
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 7):715-8.
2009: Lauren E Mays; Luk Vandenberghe; Ru Xiao; Peter Bell; Hyun-Joo Nam; Mavis Agbandje-McKenna; James M Wilson
Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6051-60.
2009: Katherine H Sippel; Arthur H Robbins; Robbie Reutzel; Susan K Boehlein; Kazunori Namiki; Steve Goodison; Mavis Agbandje-McKenna; Charles J Rosser; Robert McKenna
Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis.
Journal of bacteriology 2009;191(8):2585-92.
2009: Lin Yang; Jiangang Jiang; Lauren M Drouin; Mavis Agbandje-McKenna; Chunlian Chen; Chunping Qiao; Dongqiuye Pu; Xiaoyun Hu; Dazhi Wang; J Li; Xiao Xiao
A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3946-51.
2009: Arthur H Robbins; Ben M Dunn; Mavis Agbandje-McKenna; Robert McKenna
Crystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data Bank.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 3):294-6.
2009: Hazel C Levy; valorie bowman; Lakshmanan Govindasamy; Robert McKenna; Kevin Nash; Kenneth H Warrington; Weijun Chen; Nicholas Muzyczka; Xiaodong Yan; Timothy S Baker; Mavis Agbandje-McKenna
Heparin binding induces conformational changes in Adeno-associated virus serotype 2.
Journal of structural biology 2009;165(3):146-56.
2009: Caroli Genis; Katherine H Sippel; Nicolette Case; Wengang Cao; Balendu Sankara Avvaru; Lawrence J Tartaglia; Lakshmanan Govindasamy; Chingkuang Tu; Mavis Agbandje-McKenna; David N Silverman; Charles J Rosser; Robert McKenna
Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties.
Biochemistry 2009;48(6):1322-31.
2008: Li Zhong; Baozheng Li; Giridhararao Jayandharan; Cathryn Mah; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Roland W Herzog; Kirsten A Weigel-Van Aken; Jacqueline A Hobbs; Sergei Zolotukhin; Nicholas Muzyczka; Arun Srivastava
Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression.
Virology 2008;381(2):194-202.
2008: John F Domsic; Balendu Sankara Avvaru; Chae Un Kim; Sol M Gruner; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Entrapment of carbon dioxide in the active site of carbonic anhydrase II.
The Journal of biological chemistry 2008;283(45):30766-71.
2008: Katherine H Sippel; Arthur H Robbins; Robbie Reutzel; John Domsic; Susan K Boehlein; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Charles J Rosser; Robert McKenna
Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 11):1172-8.
2008: Igor Etingov; Refael Itah; Michal Mincberg; Ayelet Keren-Naus; Hyun-Joo Nam; Mavis Agbandje-McKenna; Claytus Davis
An extension of the Minute Virus of Mice tissue tropism.
Virology 2008;379(2):245-55.
2008: Karin Peterson; Susan Pourciau; Min Du; Rachel Lacasse; Melissa Pathmajeyan; David Poulsen; Mavis Agbandje-McKenna; Kathy Wehrly; Bruce Chesebro
Neurovirulence of polytropic murine retrovirus is influenced by two separate regions on opposite sides of the envelope protein receptor binding domain.
Journal of virology 2008;82(17):8906-10.
2008: Michael Schmidt; Lakshmanan Govindasamy; Sandra Afione; Nikola Kaludov; Mavis Agbandje-McKenna; John A Chiorini
Molecular characterization of the heparin-dependent transduction domain on the capsid of a novel adeno-associated virus isolate, AAV(VR-942).
Journal of virology 2008;82(17):8911-6.
2008: Wuping Li; Aravind Asokan; Zhijian Wu; Terry Van Dyke; Nina DiPrimio; Jarrod S Johnson; Lakshmanan Govindaswamy; Mavis Agbandje-McKenna; Stefan Leichtle; D Eugene Redmond; Thomas J McCown; Kimberly B Petermann; Norman E Sharpless; R Jude Samulski
Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(7):1252-60.
2008: Li Zhong; Baozheng Li; Cathryn Mah; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Mario Cooper; Roland W Herzog; Irene Zolotukhin; Kenneth H Warrington; Kirsten A Weigel-Van Aken; Jacqueline A Hobbs; Sergei Zolotukhin; Nicholas Muzyczka; Arun Srivastava
Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7827-32.
2008: Nina DiPrimio; Aravind Asokan; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; R Jude Samulski
Surface loop dynamics in adeno-associated virus capsid assembly.
Journal of virology 2008;82(11):5178-89.
2008: Albert A Barrese; Caroli Genis; S Zoe Fisher; Jared N Orwenyo; Mudalige Thilak Kumara; Subodh K Dutta; Eric Phillips; James J Kiddle; Chingkuang Tu; David N Silverman; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Robert McKenna; Brian C Tripp
Inhibition of carbonic anhydrase II by thioxolone: a mechanistic and structural study.
Biochemistry 2008;47(10):3174-84.
2008: Félicie Faucon Andersen; Bjarne Knudsen; Cristiano L P Oliveira; Rikke From Frøhlich; Dinna Barthold Krüger; Jörg Bungert; Mavis Agbandje-McKenna; Robert McKenna; Sissel Juul; Christopher Veigaard; Jørn Koch; John L Rubinstein; Bernt Guldbrandtsen; Marianne S Hede; Göran Karlsson; Anni H Andersen; Jan Skov Pedersen; Birgitta R Knudsen
Assembly and structural analysis of a covalently closed nano-scale DNA cage.
Nucleic acids research 2008;36(4):1113-9.
2008: José C Clemente; Arthur Robbins; Paula Graña; M Rita Paleo; Juan F Correa; M Carmen Villaverde; F Javier Sardina; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Robert McKenna; Ben M Dunn; Fredy Sussman
Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation.
Journal of medicinal chemistry 2008;51(4):852-60.
2008: Kim M Van Vliet; Veronique Blouin; Nicole Brument; Mavis Agbandje-McKenna; Richard O Snyder
The role of the adeno-associated virus capsid in gene transfer.
Methods in molecular biology (Clifton, N.J.) 2008;437():51-91.
2007: Rebecca E Moose; José C Clemente; Larry R Jackson; Minh Ngo; Kimberly Wooten; Richard Chang; Antonette Bennett; Sibani Chakraborty; Charles A Yowell; John B Dame; Mavis Agbandje-McKenna; Ben M Dunn
Analysis of binding interactions of pepsin inhibitor-3 to mammalian and malarial aspartic proteases.
Biochemistry 2007;46(49):14198-205.
2007: Odayme Quesada; Brittney Gurda; Lakshmanan Govindasamy; Robert McKenna; Erik Kohlbrenner; George Aslanidi; Sergei Zolotukhin; Nicholas Muzyczka; Mavis Agbandje-McKenna
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 12):1073-6.
2007: Hyun-Joo Nam; Michael Douglas Lane; Eric Padron; Brittney Gurda; Robert McKenna; Erik Kohlbrenner; George Aslanidi; Barry Byrne; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Structure of adeno-associated virus serotype 8, a gene therapy vector.
Journal of virology 2007;81(22):12260-71.
2007: Joshua C Grieger; Jarrod S Johnson; Brittney Gurda-Whitaker; Mavis Agbandje-McKenna; R Jude Samulski
Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions.
Journal of virology 2007;81(15):7833-43.
2007: Li Zhong; Weihong Zhao; Jianqing Wu; Baozheng Li; Sergei Zolotukhin; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Arun Srivastava
A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(7):1323-30.
2007: S Zoë Fisher; Chingkuang Tu; Deepa Bhatt; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Robert McKenna; David N Silverman
Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II.
Biochemistry 2007;46(12):3803-13.
2007: S Zoë Fisher; C Mark Maupin; Monika Budayova-Spano; Lakshmanan Govindasamy; Chingkuang Tu; Mavis Agbandje-McKenna; David N Silverman; Gregory A Voth; Robert McKenna
Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism.
Biochemistry 2007;46(11):2930-7.
2006: Edward B Miller; Brittney Gurda-Whitaker; Lakshmanan Govindasamy; Robert McKenna; Sergei Zolotukhin; Nicholas Muzyczka; Mavis Agbandje-McKenna
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 12):1271-4.
2006: Kim Van Vliet; Veronique Blouin; Mavis Agbandje-McKenna; Richard O Snyder
Proteolytic mapping of the adeno-associated virus capsid.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(6):809-21.
2006: Lakshmanan Govindasamy; Eric Padron; Robert McKenna; Nicholas Muzyczka; Nikola Kaludov; John A Chiorini; Mavis Agbandje-McKenna
Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.
Journal of virology 2006;80(23):11556-70.
2006: Zhijian Wu; Aravind Asokan; Joshua C Grieger; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; R Jude Samulski
Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes.
Journal of virology 2006;80(22):11393-7.
2006: Zhijian Wu; Edward Miller; Mavis Agbandje-McKenna; R Jude Samulski
Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6.
Journal of virology 2006;80(18):9093-103.
2006: Aravind Asokan; Julie B Hamra; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; R Jude Samulski
Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry.
Journal of virology 2006;80(18):8961-9.
2006: Hyun-Joo Nam; Brittney Gurda-Whitaker; Wand Yee Gan; Shawen Ilaria; Robert McKenna; Padmaja Mehta; Richard A Alvarez; Mavis Agbandje-McKenna
Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation.
The Journal of biological chemistry 2006;281(35):25670-7.
2006: Meera Sitharam; Mavis Agbandje-McKenna
Modeling virus self-assembly pathways: avoiding dynamics using geometric constraint decomposition.
Journal of computational biology : a journal of computational molecular cell biology 2006;13(6):1232-65.
2006: S Zoë Fisher; Lakshmanan Govindasamy; Nicholas Boyle; Mavis Agbandje-McKenna; David N Silverman; G Michael Blackburn; Robert McKenna
X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 7):618-22.
2006: José C Clemente; Roxana M Coman; Michele M Thiaville; Linda K Janka; Jennifer A Jeung; Sarawut Nukoolkarn; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Robert McKenna; Wichet Leelamanit; Maureen M Goodenow; Ben M Dunn
Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir.
Biochemistry 2006;45(17):5468-77.
2006: José C Clemente; Lakshmanan Govindasamy; Amrita Madabushi; S Zoë Fisher; Rebecca E Moose; Charles A Yowell; Koushi Hidaka; Tooru Kimura; Yoshio Hayashi; Yoshiaki Kiso; Mavis Agbandje-McKenna; John B Dame; Ben M Dunn; Robert McKenna
Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 3):246-52.
2006: S Zoë Fisher; Lakshmanan Govindasamy; Chingkuang Tu; Mavis Agbandje-McKenna; David N Silverman; Hannu J Rajaniemi; Robert McKenna
Structure of human salivary alpha-amylase crystallized in a C-centered monoclinic space group.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 2):88-93.
2006: Alberto López-Bueno; Mari-Paz Rubio; Nathan Bryant; Robert McKenna; Mavis Agbandje-McKenna; José M Almendral
Host-selected amino acid changes at the sialic acid binding pocket of the parvovirus capsid modulate cell binding affinity and determine virulence.
Journal of virology 2006;80(3):1563-73.
2006: Monika Budayova-Spano; S Zoë Fisher; Marie Thérèse Dauvergne; Mavis Agbandje-McKenna; David N Silverman; Dean A A Myles; Robert McKenna
Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 1):6-9.
2005: Michael DiMattia; Lakshmanan Govindasamy; Hazel C Levy; Brittney Gurda-Whitaker; Amy Kalina; Erik Kohlbrenner; John A Chiorini; Robert McKenna; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 10):917-21.
2005: Maria Kontou; Lakshmanan Govindasamy; Hyun-Joo Nam; Nathan Bryant; Antonio Luis Llamas-Saiz; Concepción Foces-Foces; Eva Hernando; Mari-Paz Rubio; Robert McKenna; José M Almendral; Mavis Agbandje-McKenna
Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice.
Journal of virology 2005;79(17):10931-43.
2005: David M Duda; Chingkuang Tu; S Zoë Fisher; Haiqian An; Craig Yoshioka; Lakshmanan Govindasamy; Philip J Laipis; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Human carbonic anhydrase III: structural and kinetic study of catalysis and proton transfer.
Biochemistry 2005;44(30):10046-53.
2005: Catherine M Ketcham; Satoshi Anai; Robbie Reutzel; Shijie Sheng; Sheldon M Schuster; Ryan B Brenes; Mavis Agbandje-McKenna; Robert McKenna; Charles J Rosser; Susan K Boehlein
p37 Induces tumor invasiveness.
Molecular cancer therapeutics 2005;4(7):1031-8.
2005: Michael Douglas Lane; Hyun-Joo Nam; Eric Padron; Brittney Gurda-Whitaker; Erik Kohlbrenner; George Aslanidi; Barry Byrne; Robert McKenna; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 6):558-61.
2005: Eric Padron; valorie bowman; Nikola Kaludov; Lakshmanan Govindasamy; Hazel Levy; Phillip Nick; Robert McKenna; Nicholas Muzyczka; John A Chiorini; Timothy S Baker; Mavis Agbandje-McKenna
Structure of adeno-associated virus type 4.
Journal of virology 2005;79(8):5047-58.
2005: Bret B Beyer; Jodie V Johnson; Alfred Y Chung; Tang Li; Amrita Madabushi; Mavis Agbandje-McKenna; Robert McKenna; John B Dame; Ben M Dunn
Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries.
Biochemistry 2005;44(6):1768-79.
2005: Amrita Madabushi; Sibani Chakraborty; S Zoë Fisher; José C Clemente; Charles A Yowell; Mavis Agbandje-McKenna; John B Dame; Ben M Dunn; Robert McKenna
Crystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 2):228-31.
2004: Lakshmanan Govindasamy; Brenda Pedersen; Wei Lian; Thomas Kukar; Yunrong Gu; Shouguang Jin; Mavis Agbandje-McKenna; Donghai Wu; Robert McKenna
Structural insights and functional implications of choline acetyltransferase.
Journal of structural biology 2004;148(2):226-35.
2004: José C Clemente; Rebecca E Moose; Reena Hemrajani; Lisa R S Whitford; Lakshmanan Govindasamy; Robbie Reutzel; Robert McKenna; Mavis Agbandje-McKenna; Maureen M Goodenow; Ben M Dunn
Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease.
Biochemistry 2004;43(38):12141-51.
2004: Lakshmanan Govindasamy; Robbie Reutzel; Mavis Agbandje-McKenna; Robert McKenna
Structural determination of a partially hemihedrally twinned actin crystal.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 6):1040-7.
2004: Lakshmanan Govindasamy; Thomas Kukar; Wei Lian; Brenda Pedersen; Yunrong Gu; Mavis Agbandje-McKenna; Shouguang Jin; Robert McKenna; Donghai Wu
Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase.
Journal of structural biology 2004;146(3):416-24.
2004: Robbie Reutzel; Craig Yoshioka; Lakshmanan Govindasamy; Elena G Yarmola; Mavis Agbandje-McKenna; michael bubb; Robert McKenna
Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
Journal of structural biology 2004;146(3):291-301.
2004: Carolina G Casado; G Javier Ortiz; Eric Padron; Samantha J Bean; Robert McKenna; Mavis Agbandje-McKenna; Margaret I Boulton
Isolation and characterization of subgenomic DNAs encapsidated in "single" T = 1 isometric particles of Maize streak virus.
Virology 2004;323(1):164-71.
2004: Robert Walters; Mavis Agbandje-McKenna; valorie bowman; Thomas O Moninger; Norman H Olson; Michael Seiler; John A Chiorini; Timothy S Baker; Joseph Zabner
Structure of adeno-associated virus serotype 5.
Journal of virology 2004;78(7):3361-71.
2004: Wei Lian; Yunrong Gu; Brenda Pedersen; Thomas Kukar; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Shouguang Jin; Robert McKenna; Donghai Wu
Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 2):374-5.
2003: Lakshmanan Govindasamy; Karsten Hueffer; Colin R Parrish; Mavis Agbandje-McKenna
Structures of host range-controlling regions of the capsids of canine and feline parvoviruses and mutants.
Journal of virology 2003;77(22):12211-21.
2003: Karsten Hueffer; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Colin R Parrish
Combinations of two capsid regions controlling canine host range determine canine transferrin receptor binding by canine and feline parvoviruses.
Journal of virology 2003;77(18):10099-105.
2003: Shaun R Opie; Kenneth H Warrington; Mavis Agbandje-McKenna; Sergei Zolotukhin; Nicholas Muzyczka
Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding.
Journal of virology 2003;77(12):6995-7006.
2003: Donghai Wu; Lakshmanan Govindasamy; Wei Lian; Yunrong Gu; Thomas Kukar; Mavis Agbandje-McKenna; Robert McKenna
Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer.
The Journal of biological chemistry 2003;278(15):13159-65.
2003: Nikola Kaludov; Eric Padron; Lakshmanan Govindasamy; Robert McKenna; John A Chiorini; Mavis Agbandje-McKenna
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 4.
Virology 2003;306(1):1-6.
2003: David M Duda; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Chingkuang Tu; David N Silverman; Robert McKenna
The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 1):93-104.
2002: Robbie Reutzel; Susan K Boehlein; Lakshmanan Govindasamy; Ryan B Brenes; Mavis Agbandje-McKenna; Sheldon M Schuster; Robert McKenna
Crystallization and preliminary X-ray analysis of the tumor metastasis factor p37.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):2141-4.
2002: Wei Lian; Lakshmanan Govindasamy; Yunrong Gu; Thomas Kukar; Mavis Agbandje-McKenna; Robert McKenna; Donghai Wu
Crystallization and preliminary X-ray crystallographic studies on recombinant human carnitine acetyltransferase.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 7):1193-4.
2002: michael bubb; Lakshmanan Govindasamy; Elena G Yarmola; Sergey M Vorobiev; Steven C Almo; Thayumanasamy Somasundaram; Michael S Chapman; Mavis Agbandje-McKenna; Robert McKenna
Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution.
The Journal of biological chemistry 2002;277(23):20999-1006.
2002: Karie L Brentlinger; Susan Hafenstein; Christopher R Novak; Bentley A Fane; Robert Borgon; Robert McKenna; Mavis Agbandje-McKenna
Microviridae, a family divided: isolation, characterization, and genome sequence of phiMH2K, a bacteriophage of the obligate intracellular parasitic bacterium Bdellovibrio bacteriovorus.
Journal of bacteriology 2002;184(4):1089-94.
2001: Marshall E Bloom; Sonja Best; Stanley F Hayes; R D Wells; James B Wolfinbarger; R McKenna; Mavis Agbandje-McKenna
Identification of aleutian mink disease parvovirus capsid sequences mediating antibody-dependent enhancement of infection, virus neutralization, and immune complex formation.
Journal of virology 2001;75(22):11116-27.
2001: David M Duda; Chingkuang Tu; Minzhang Qian; Philip J Laipis; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
Biochemistry 2001;40(6):1741-8.
2001: Wei Zhang; Norman H Olson; Timothy S Baker; L Faulkner; Mavis Agbandje-McKenna; Margaret I Boulton; JW Davies; Robert McKenna
Structure of the Maize streak virus geminate particle.
Virology 2001;279(2):471-7.
2000: P Wu; W Xiao; Thomas J Conlon; Jeffrey Hughes; Mavis Agbandje-McKenna; Thomas Ferkol; Terence Flotte; Nicholas Muzyczka
Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism.
Journal of virology 2000;74(18):8635-47.
2000: Eleuterio Lombardo; Juan Ramirez; Mavis Agbandje-McKenna; José M Almendral
A beta-stranded motif drives capsid protein oligomers of the parvovirus minute virus of mice into the nucleus for viral assembly.
Journal of virology 2000;74(8):3804-14.
2000: Eva Hernando; Antonio Luis Llamas-Saiz; Concepción Foces-Foces; Robert McKenna; I Portman; Mavis Agbandje-McKenna; José M Almendral
Biochemical and physical characterization of parvovirus minute virus of mice virus-like particles.
Virology 2000;267(2):299-309.
1999: R McKenna; NH Olson; Paul R Chipman; Timothy S Baker; T F Booth; J Christensen; Bent Aasted; JM Fox; Marshall E Bloom; James B Wolfinbarger; Mavis Agbandje-McKenna
Three-dimensional structure of Aleutian mink disease parvovirus: implications for disease pathogenicity.
Journal of virology 1999;73(8):6882-91.
1998: Mavis Agbandje-McKenna; Antonio Luis Llamas-Saiz; F Wang; Peter Tattersall; Michael G Rossmann
Functional implications of the structure of the murine parvovirus, minute virus of mice.
Structure (London, England : 1993) 1998;6(11):1369-81.
1998: Paul R Chipman; Mavis Agbandje-McKenna; J Renaudin; Timothy S Baker; Robert McKenna
Structural analysis of the Spiroplasma virus, SpV4: implications for evolutionary variation to obtain host diversity among the Microviridae.
Structure (London, England : 1993) 1998;6(2):135-45.
1997: Antonio Luis Llamas-Saiz; Mavis Agbandje-McKenna; W R Wikoff; J Bratton; Peter Tattersall; Michael G Rossmann
Structure determination of minute virus of mice.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 1):93-102.
1997: Marshall E Bloom; D A Martin; K L Oie; M E Huhtanen; F Costello; James B Wolfinbarger; Stanley F Hayes; Mavis Agbandje-McKenna
Expression of Aleutian mink disease parvovirus capsid proteins in defined segments: localization of immunoreactive sites and neutralizing epitopes to specific regions.
Journal of virology 1997;71(1):705-14.
1996: Antonio Luis Llamas-Saiz; Mavis Agbandje-McKenna; J S Parker; A T Wahid; Colin R Parrish; Michael G Rossmann
Structural analysis of a mutation in canine parvovirus which controls antigenicity and host range.
Virology 1996;225(1):65-71.
1996: Paul R Chipman; Mavis Agbandje-McKenna; S Kajigaya; K E Brown; N S Young; Timothy S Baker; Michael G Rossmann
Cryo-electron microscopy studies of empty capsids of human parvovirus B19 complexed with its cellular receptor.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7502-6.