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Christiane Obled

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Gilles Mayot; Karine Vidal; Carole Migné; Denis Breuillé; Stephanie Blum; Christiane Obled; Isabelle Papet
Presence of age-associated low-grade inflammation does not worsen the body response to bacterial infection in old male rats.
Jean-Philippe Godin; Denis Breuillé; Christiane Obled; Isabelle Papet; Henk Schierbeek; Gérard Hopfgartner; Laurent B Fay
Liquid and gas chromatography coupled to isotope ratio mass spectrometry for the determination of 13C-valine isotopic ratios in complex biological samples.
Isabelle Papet; Nathalie Meunier; Fabienne Béchereau; Françoise Glomot; Christiane Obled; Charles Coudray
Effect of zinc supplementation on protein metabolism in late-middle-aged men: The Zenith study.

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2011: Gilles Mayot; Karine Vidal; Carole Migné; Denis Breuillé; Stephanie Blum; Christiane Obled; Isabelle Papet
Presence of age-associated low-grade inflammation does not worsen the body response to bacterial infection in old male rats.
Biogerontology 2011;12(2):133-45.
2008: Jean-Philippe Godin; Denis Breuillé; Christiane Obled; Isabelle Papet; Henk Schierbeek; Gérard Hopfgartner; Laurent B Fay
Liquid and gas chromatography coupled to isotope ratio mass spectrometry for the determination of 13C-valine isotopic ratios in complex biological samples.
Journal of mass spectrometry : JMS 2008;43(10):1334-43.
2008: Isabelle Papet; Nathalie Meunier; Fabienne Béchereau; Françoise Glomot; Christiane Obled; Charles Coudray
Effect of zinc supplementation on protein metabolism in late-middle-aged men: The Zenith study.
Nutrition (Burbank, Los Angeles County, Calif.) 2008;24(2):155-61.
2007: Gilles Mayot; Karine Vidal; Lydie Combaret; Denis Breuillé; Stephanie Blum; Christiane Obled; Isabelle Papet
Presence of low-grade inflammation in old rats does not worsen skeletal muscle loss under an endotoxemic and dietary stress.
Experimental gerontology 2007;42(12):1167-75.
2007: Magali Faure; Frédérique Choné; Christine Mettraux; Jean-Philippe Godin; Fabienne Béchereau; Jacques Vuichoud; Isabelle Papet; Denis Breuillé; Christiane Obled
Threonine utilization for synthesis of acute phase proteins, intestinal proteins, and mucins is increased during sepsis in rats.
The Journal of nutrition 2007;137(7):1802-7.
2007: Gilles Mayot; Karine Vidal; Jean-Francois MARTIN; Denis Breuillé; Stephanie Blum; Christiane Obled; Isabelle Papet
Prognostic values of alpha2-macroglobulin, fibrinogen and albumin in regards to mortality and frailty in old rats.
Experimental gerontology 2007;42(6):498-505.
2007: Caroline Puel; Julie Mardon; Séraphin Kati-Coulibaly; Marie-Jeanne Davicco; Patrice Lebecque; Christiane Obled; Edmond Rock; Marie-Noëlle Horcajada; Apostolos Agalias; Leandros A Skaltsounis; Véronique Coxam
Black Lucques olives prevented bone loss caused by ovariectomy and talc granulomatosis in rats.
The British journal of nutrition 2007;97(5):1012-20.
2007: Odile Mansoor; Denis Breuillé; Fabienne Béchereau; Caroline Buffière; Corinne Pouyet; Bernard Beaufrère; Jacques Vuichoud; Martin Van't-Of; Christiane Obled
Effect of an enteral diet supplemented with a specific blend of amino acid on plasma and muscle protein synthesis in ICU patients.
Clinical nutrition (Edinburgh, Scotland) 2007;26(1):30-40.
2006: Caroline Puel; Jacinthe Mathey; Apostolos Agalias; Séraphin Kati-Coulibaly; Julie Mardon; Christiane Obled; Marie-Jeanne Davicco; Patrice Lebecque; Marie-Noëlle Horcajada; Alexios-Leandros Skaltsounis; Véronique Coxam
Dose-response study of effect of oleuropein, an olive oil polyphenol, in an ovariectomy/inflammation experimental model of bone loss in the rat.
Clinical nutrition (Edinburgh, Scotland) 2006;25(5):859-68.
2006: Denis Breuillé; Fabienne Béchereau; Caroline Buffière; Philippe Denis; Corinne Pouyet; Christiane Obled
Beneficial effect of amino acid supplementation, especially cysteine, on body nitrogen economy in septic rats.
Clinical nutrition (Edinburgh, Scotland) 2006;25(4):634-42.
2006: Magali Faure; Christine Mettraux; Denis Moennoz; Jean-Philippe Godin; Jacques Vuichoud; Florence Rochat; Denis Breuillé; Christiane Obled; Irène Corthésy-Theulaz
Specific amino acids increase mucin synthesis and microbiota in dextran sulfate sodium-treated rats.
The Journal of nutrition 2006;136(6):1558-64.
2006: Federico Lara-Villoslada; Elisabeth Debras; Ana Nieto; Angel Concha; Julio Gálvez; Eduardo López-Huertas; Julio Boza; Christiane Obled; Jordi Xaus
Oligosaccharides isolated from goat milk reduce intestinal inflammation in a rat model of dextran sodium sulfate-induced colitis.
Clinical nutrition (Edinburgh, Scotland) 2006;25(3):477-88.
2006: Sabine Mercier; Denis Breuillé; Caroline Buffière; Johan Gimonet; Isabelle Papet; Philippe Patureau Mirand; Christiane Obled
Methionine kinetics are altered in the elderly both in the basal state and after vaccination.
The American journal of clinical nutrition 2006;83(2):291-8.
2005: Caroline Puel; A Quintin; Jacinthe Mathey; Christiane Obled; Marie-Jeanne Davicco; Patrice Lebecque; Séraphin Kati-Coulibaly; Marie-Noëlle Horcajada; Véronique Coxam
Prevention of bone loss by phloridzin, an apple polyphenol, in ovariectomized rats under inflammation conditions.
Calcified tissue international 2005;77(5):311-8.
2005: Mimoun El Yousfi; Sabine Mercier; Denis Breuillé; Philippe Denis; Isabelle Papet; Philippe Patureau Mirand; Christiane Obled
The inflammatory response to vaccination is altered in the elderly.
Mechanisms of ageing and development 2005;126(8):874-81.
2005: Eduardo J Schiffrin; Mimoun El Yousfi; Magali Faure; Lydie Combaret; Anne Donnet; Stephanie Blum; Christiane Obled; Denis Breuillé
Milk casein-based diet containing TGF-beta controls the inflammatory reaction in the HLA-B27 transgenic rat model.
JPEN. Journal of parenteral and enteral nutrition 2005;29(4 Suppl):S141-8; discussion S149-50, S184-8.
2004: Caroline Puel; A Quintin; Apostolos Agalias; Jacinthe Mathey; Christiane Obled; Andrzej Mazur; Marie-Jeanne Davicco; Patrice Lebecque; Alexios-Leandros Skaltsounis; Véronique Coxam
Olive oil and its main phenolic micronutrient (oleuropein) prevent inflammation-induced bone loss in the ovariectomised rat.
The British journal of nutrition 2004;92(1):119-27.
2004: Magali Faure; Denis Moënnoz; Christine Mettraux; Franck Montigon; E J Schiffrin; Christiane Obled; Denis Breuillé; Julio Boza
The chronic colitis developed by HLA-B27 transgenic rats is associated with altered in vivo mucin synthesis.
Digestive diseases and sciences 2004;49(2):339-46.
2004: Laurent Mosoni; Denis Breuillé; Caroline Buffière; Christiane Obled; Philippe Patureau Mirand
Age-related changes in glutathione availability and skeletal muscle carbonyl content in healthy rats.
Experimental gerontology 2004;39(2):203-10.
2003: Mimoun El Yousfi; Denis Breuillé; Isabelle Papet; Stéphanie Blum; Marc André; Laurent Mosoni; Philippe Denis; Caroline Buffière; Christiane Obled
Increased tissue protein synthesis during spontaneous inflammatory bowel disease in HLA-B27 rats.
Clinical science (London, England : 1979) 2003;105(4):437-46.
2003: Magali Faure; Denis Moënnoz; Franck Montigon; Christine Mettraux; Sabine Mercier; E J Schiffrin; Christiane Obled; Denis Breuillé; Julio Boza
Mucin production and composition is altered in dextran sulfate sodium-induced colitis in rats.
Digestive diseases and sciences 2003;48(7):1366-73.
2003: Benoît Ruot; Isabelle Papet; Fabienne Bechereau; Philippe Denis; Caroline Buffiere; Johan Gimonet; Françoise Glomot; Mimoun Elyousfi; Denis Breuille; Christiane Obled
Increased albumin plasma efflux contributes to hypoalbuminemia only during early phase of sepsis in rats.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;284(3):R707-13.
2003: Isabelle Papet; dominique dardevet; Claire Sornet; Fabienne Béchereau; Jacques Prugnaud; Corinne Pouyet; Christiane Obled
Acute phase protein levels and thymus, spleen and plasma protein synthesis rates differ in adult and old rats.
The Journal of nutrition 2003;133(1):215-9.
2002: Isabelle Papet; Benoît Ruot; Denis Breuillé; Stéphane Walrand; Marie-Chantal Farges; Marie-Paule Vasson; Christiane Obled
Bacterial infection affects protein synthesis in primary lymphoid tissues and circulating lymphocytes of rats.
The Journal of nutrition 2002;132(7):2028-32.
2002: Sabine Mercier; Denis Breuillé; Laurent Mosoni; Christiane Obled; Philippe Patureau Mirand
Chronic inflammation alters protein metabolism in several organs of adult rats.
The Journal of nutrition 2002;132(7):1921-8.
2002: Christiane Obled; Isabelle Papet; Denis Breuillé
Metabolic bases of amino acid requirements in acute diseases.
Current opinion in clinical nutrition and metabolic care 2002;5(2):189-97.
2002: Lydie Combaret; Thomas Tilignac; Agnès Claustre; Laure Voisin; Daniel Taillandier; Christiane Obled; Keiji Tanaka; Didier Attaix
Torbafylline (HWA 448) inhibits enhanced skeletal muscle ubiquitin-proteasome-dependent proteolysis in cancer and septic rats.
The Biochemical journal 2002;361(Pt 2):185-92.
2002: Benoît Ruot; Fabienne Béchereau; Gérard Bayle; Denis Breuillé; Christiane Obled
The response of liver albumin synthesis to infection in rats varies with the phase of the inflammatory process.
Clinical science (London, England : 1979) 2002;102(1):107-14.
2001: C Deval; S Mordier; Christiane Obled; Daniel Bechet; Lydie Combaret; Didier Attaix; M Ferrara
Identification of cathepsin L as a differentially expressed message associated with skeletal muscle wasting.
The Biochemical journal 2001;360(Pt 1):143-50.
2001: I Savary; Elisabeth Debras; dominique dardevet; F Rambourdin; Marie-Paule Vasson; Christiane Obled; Jean Grizard
Evidence for an alteration of plasma and liver proteins response to dexamethasone in aging rats.
Mechanisms of ageing and development 2001;122(1):105-20.
2000: T Malmezat; Denis Breuillé; Corinne Pouyet; Caroline Buffière; Philippe Denis; Philippe Patureau Mirand; Christiane Obled
Methionine transsulfuration is increased during sepsis in rats.
American journal of physiology. Endocrinology and metabolism 2000;279(6):E1391-7.
2000: Benoît Ruot; Denis Breuillé; F Rambourdin; Gérard Bayle; P Capitan; Christiane Obled
Synthesis rate of plasma albumin is a good indicator of liver albumin synthesis in sepsis.
American journal of physiology. Endocrinology and metabolism 2000;279(2):E244-51.
2000: T Malmezat; Denis Breuillé; P Capitan; Philippe Patureau Mirand; Christiane Obled
Glutathione turnover is increased during the acute phase of sepsis in rats.
The Journal of nutrition 2000;130(5):1239-46.
2000: Denis Breuillé; Christiane Obled
Cysteine and glutathione in catabolic states.
Nestlé Nutrition workshop series. Clinical & performance programme 2000;3():173-91; discussion 191-7.
1999: TC Vary; dominique dardevet; Jean Grizard; Laure Voisin; Caroline Buffiere; Philippe Denis; Denis Breuille; Christiane Obled
Pentoxifylline improves insulin action limiting skeletal muscle catabolism after infection.
The Journal of endocrinology 1999;163(1):15-24.
1999: P Capitan; T Malmezat; Denis Breuillé; Christiane Obled
Gas chromatographic-mass spectrometric analysis of stable isotopes of cysteine and glutathione in biological samples.
Journal of chromatography. B, Biomedical sciences and applications 1999;732(1):127-35.
1999: Denis Breuille; Laure Voisin; M Contrepois; Marie-Agnès Arnal; F Rose; Christiane Obled
A sustained rat model for studying the long-lasting catabolic state of sepsis.
Infection and immunity 1999;67(3):1079-85.
1999: Jean Grizard; dominique dardevet; Michèle Balage; D Larbaud; S Sinaud; I Savary; K Grzelkowska; Cécile Rochon; Igor Tauveron; Christiane Obled
Insulin action on skeletal muscle protein metabolism during catabolic states.
Reproduction, nutrition, development 1999;39(1):61-74.
1998: Laure Voisin; Denis Breuillé; Benoît Ruot; C Rallière; F Rambourdin; M Dalle; Christiane Obled
Cytokine modulation by PX differently affects specific acute phase proteins during sepsis in rats.
The American journal of physiology 1998;275(5 Pt 2):R1412-9.
1998: TC Vary; dominique dardevet; Jean Grizard; Laure Voisin; Caroline Buffiere; Philippe Denis; Denis Breuille; Christiane Obled
Differential regulation of skeletal muscle protein turnover by insulin and IGF-I after bacteremia.
The American journal of physiology 1998;275(4 Pt 1):E584-93.
1998: Denis Breuillé; Marie-Agnès Arnal; F Rambourdin; Gérard Bayle; D Levieux; Christiane Obled
Sustained modifications of protein metabolism in various tissues in a rat model of long-lasting sepsis.
Clinical science (London, England : 1979) 1998;94(4):413-23.
1998: T Malmezat; Denis Breuillé; Corinne Pouyet; Philippe Patureau Mirand; Christiane Obled
Metabolism of cysteine is modified during the acute phase of sepsis in rats.
The Journal of nutrition 1998;128(1):97-105.
1997: Odile Mansoor; M Cayol; Pierre Gachon; Yves Boirie; P Schoeffler; Christiane Obled; Bernard Beaufrère
Albumin and fibrinogen syntheses increase while muscle protein synthesis decreases in head-injured patients.
The American journal of physiology 1997;273(5 Pt 1):E898-902.
1997: J Le Boucher; Christiane Obled; Marie-Chantal Farges; Luc Cynober
Ornithine alpha-ketoglutarate modulates tissue protein metabolism in burn-injured rats.
The American journal of physiology 1997;273(3 Pt 1):E557-63.
1997: Isabelle Papet; Piotr Ostaszewski; Françoise Glomot; Christiane Obled; Magali Faure; Gérard Bayle; Steven Nissen; Marie-Agnès Arnal; Jean Grizard
The effect of a high dose of 3-hydroxy-3-methylbutyrate on protein metabolism in growing lambs.
The British journal of nutrition 1997;77(6):885-96.
1997: TC Vary; dominique dardevet; Christiane Obled; Corinne Pouyet; Denis Breuille; Jean Grizard
Modulation of skeletal muscle lactate metabolism following bacteremia by insulin or insulin-like growth factor-I: effects of pentoxifylline.
Shock (Augusta, Ga.) 1997;7(6):432-8.
1997: M Cayol; Yves Boirie; F Rambourdin; Jacques Prugnaud; Pierre Gachon; Bernard Beaufrère; Christiane Obled
Influence of protein intake on whole body and splanchnic leucine kinetics in humans.
The American journal of physiology 1997;272(4 Pt 1):E584-91.
1996: A Egerland; J P Reynier; O Ballevre; J Dicostanzo; Christiane Obled; M Arnal
Protein synthesis measurement in cancer patients with 13C valine.
Clinica chimica acta; international journal of clinical chemistry 1996;252(1):51-60.
1996: N L Floc'h; Christiane Obled; Bernard Sève
In vivo threonine oxidation in growing pigs fed on diets with graded levels of threonine.
The British journal of nutrition 1996;75(6):825-37.
1996: M Cayol; Yves Boirie; Jacques Prugnaud; Pierre Gachon; B Beaufrere; Christiane Obled
Precursor pool for hepatic protein synthesis in humans: effects of tracer route infusion and dietary proteins.
The American journal of physiology 1996;270(6 Pt 1):E980-7.
1996: Laure Voisin; Denis Breuillé; Lydie Combaret; Corinne Pouyet; Daniel Taillandier; Eveline Aurousseau; Christiane Obled; Didier Attaix
Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways.
The Journal of clinical investigation 1996;97(7):1610-7.
1995: Nathalie Le Floc'h; Christiane Obled; Bernard Sève
In vivo threonine oxidation rate is dependent on threonine dietary supply in growing pigs fed low to adequate levels.
The Journal of nutrition 1995;125(10):2550-62.
1995: M Cayol; Igor Tauveron; F Rambourdin; Jacques Prugnaud; Pierre Gachon; Philippe Thieblot; Jean Grizard; Christiane Obled
Whole-body protein turnover and hepatic protein synthesis are increased by vaccination in man.
Clinical science (London, England : 1979) 1995;89(4):389-96.
1995: Igor Tauveron; S Charrier; C Champredon; Y Bonnet; C Berry; Gérard Bayle; Jacques Prugnaud; Christiane Obled; Jean Grizard; P Thiéblot
Response of leucine metabolism to hyperinsulinemia under amino acid replacement in experimental hyperthyroidism.
The American journal of physiology 1995;269(3 Pt 1):E499-507.
1995: M Cayol; P Capitan; Jacques Prugnaud; M Genest; B Beaufrre; Christiane Obled
Cation-exchange resins release amino acids: consequences for tracer studies.
Analytical biochemistry 1995;227(2):392-4.
1995: Laurent Mosoni; M C Valluy; B Serrurier; Jacques Prugnaud; Christiane Obled; C Y Guezennec; Philippe Patureau Mirand
Altered response of protein synthesis to nutritional state and endurance training in old rats.
The American journal of physiology 1995;268(2 Pt 1):E328-35.
1994: C Collin-Vidal; M Cayol; Christiane Obled; F Ziegler; G Bommelaer; B Beaufrere
Leucine kinetics are different during feeding with whole protein or oligopeptides.
The American journal of physiology 1994;267(6 Pt 1):E907-14.
1994: Denis Breuille; F Rose; Marie-Agnès Arnal; C Melin; Christiane Obled
Sepsis modifies the contribution of different organs to whole-body protein synthesis in rats.
Clinical science (London, England : 1979) 1994;86(6):663-9.
1993: Denis Breuillé; M C Farge; F Rosé; Marie-Agnès Arnal; Didier Attaix; Christiane Obled
Pentoxifylline decreases body weight loss and muscle protein wasting characteristics of sepsis.
The American journal of physiology 1993;265(4 Pt 1):E660-6.
1993: Bernard Sève; O Ballèvre; P Ganier; J Noblet; Jacques Prugnaud; Christiane Obled
Recombinant porcine somatotropin and dietary protein enhance protein synthesis in growing pigs.
The Journal of nutrition 1993;123(3):529-40.
1992: Christiane Obled; Marie-Agnès Arnal
Contribution of skin to whole-body protein synthesis in rats at different stages of maturity.
The Journal of nutrition 1992;122(11):2167-73.
1991: Christiane Obled; Marie-Agnès Arnal
Age-related changes in whole-body amino acid kinetics and protein turnover in rats.
The Journal of nutrition 1991;121(12):1990-8.
1989: Christiane Obled; F Barre; D J Millward; Marie-Agnès Arnal
Whole body protein synthesis: studies with different amino acids in the rat.
The American journal of physiology 1989;257(5 Pt 1):E639-46.
1987: Marie-Agnès Arnal; Christiane Obled; Didier Attaix; P Patureau-Mirand; D Bonin
Dietary control of protein turnover.
Diabète & métabolisme 1987;13(6):630-42.
1981: Christiane Obled; M Alric; Marie-Agnès Arnal; G Fauconneau
[Leucine flux: total flux, oxidative catabolism, protein synthesis and breakdown during development in the rat].
Reproduction, nutrition, development 1981;21(2):279-87.
1980: Christiane Obled; Marie-Agnès Arnal; C Valin
Variations through the day of hepatic and muscular cathepsin A (carboxypeptidase A; EC 3.4.12.2), C (dipeptidyl peptidase; EC 3.4.14.1) and D (endopeptidase D; EC 3.4.23.5) activities and free amino acids of blood in rats: influence of feeding schedule.
The British journal of nutrition 1980;44(1):61-9.