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John O'Brien

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TOP 3
Joshua S Wood; Rosie Watson; Robert Barber; Andrew M Blamire; Michael J Firbank; Urs P Mosimann; John T O'Brien
Testing Visual Perception in Dementia with Lewy Bodies and Alzheimer Disease.
Dinesh Tryambake; Andrew M Blamire; Michael J Firbank; Jiabao He; John T O'Brien; Gary A Ford
Intensive blood pressure lowering increases cerebral blood flow in older subjects with hypertension.
Gordon W Duncan; Michael J Firbank; John T O'Brien; David J Burn
Magnetic resonance imaging: a biomarker for cognitive impairment in Parkinson's disease?

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2013: Joshua S Wood; Rosie Watson; Robert Barber; Andrew M Blamire; Michael J Firbank; Urs P Mosimann; John T O'Brien
Testing Visual Perception in Dementia with Lewy Bodies and Alzheimer Disease.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013;21(6):501-8.
2013: Dinesh Tryambake; Andrew M Blamire; Michael J Firbank; Jiabao He; John T O'Brien; Gary A Ford
Intensive blood pressure lowering increases cerebral blood flow in older subjects with hypertension.
Hypertension 2013;61(6):1309-15.
2013: Gordon W Duncan; Michael J Firbank; John T O'Brien; David J Burn
Magnetic resonance imaging: a biomarker for cognitive impairment in Parkinson's disease?
Movement disorders : official journal of the Movement Disorder Society 2013;28(4):425-38.
2013: Sean J Colloby; Christopher M Davison; Michael J Firbank; Jim J Lloyd; Ian G McKeith; John-Paul Taylor; John T O'Brien
Multivariate spatial covariance analysis of 99mTc-exametazime SPECT images in dementia with Lewy bodies and Alzheimer's disease: utility in differential diagnosis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013;33(4):612-8.
2013: Joanna M Jefferis; Urs P Mosimann; John T O'Brien; Michael P Clarke; John-Paul Taylor
The influence of two common dementia types on visual symptoms.
Acta ophthalmologica 2013;91(2):e159-60.
2013: James O'Donovan; Rosie Watson; Robert Barber; Andrew M Blamire; Emma J Burton; Sean J Colloby; Michael J Firbank; John T O'Brien
Does posterior cortical atrophy on MRI discriminate between Alzheimer's disease, dementia with Lewy bodies, and normal aging?
International psychogeriatrics / IPA 2013;25(1):111-9.
2012: Emma J Burton; Evelyn Jaros; Elizabeta Mukaetova-Ladinska; Robert Barber; Robert H Perry; John T O'Brien
Quantitative neurodegenerative pathology does not explain the degree of hippocampal atrophy on MRI in degenerative dementia.
International journal of geriatric psychiatry 2012;27(12):1267-74.
2012: Alice Jordan; John T O'Brien; Claud Regnard; Julian C Hughes
Pain and distress in advanced dementia: choosing the right tools for the job.
Palliative medicine 2012;26(7):873-8.
2012: Michael J Firbank; Alida A Gouw; Domenico Inzitari; Peter Langhorne; John T O'Brien; Leonardo Pantoni; Anna Poggesi; Giovanni Pracucci; Andrew Teodorczuk; Wiesje M van der Flier; Lars-Olof Wahlund; Anders Wallin; Timo Erkinjuntti
Relationship between progression of brain white matter changes and late-life depression: 3-year results from the LADIS study.
The British journal of psychiatry : the journal of mental science 2012;201(1):40-5.
2012: Emma J Burton; Evelyn Jaros; Elizabeta B Mukaetova-Ladinska; Robert Barber; Robert H Perry; John T O'Brien
Neuropathological correlates of volumetric MRI in autopsy-confirmed Lewy body dementia.
Neurobiology of aging 2012;33(7):1228-36.
2012: John-Paul Taylor; Quoc Vuong; Sarah Pearce; Nicola Barnett; Michael J Firbank; Jiabao He; Anthea Livingstone; Ian G McKeith; John T O'Brien
Visual cortex in dementia with Lewy bodies: magnetic resonance imaging study.
The British journal of psychiatry : the journal of mental science 2012;200(6):491-8.
2012: Namrta Sinha; Michael J Firbank; John T O'Brien
Biomarkers in dementia with Lewy bodies: a review.
International journal of geriatric psychiatry 2012;27(5):443-53.
2012: Elizabeth Gemmell; Roslyn Hall; Louise Allan; Helen Bosomworth; Vincent Deramecourt; Ahmad Khundakar; Arthur E Oakley; John T O'Brien; Tuomo Polvikoski; Rajesh N. Kalaria
Hippocampal neuronal atrophy and cognitive function in delayed poststroke and aging-related dementias.
Stroke; a journal of cerebral circulation 2012;43(3):808-14.
2012: Michael J Firbank; Louise M Allan; Robert Barber; Emma J Burton; John T O'Brien; Rajesh N. Kalaria
Neuroimaging predictors of death and dementia in a cohort of older stroke survivors.
Journal of neurology, neurosurgery, and psychiatry 2012;83(3):263-7.
2012: Elizabeta B Mukaetova-Ladinska; Zeinab Abdel-All; Joana Andrade; Peter W James; Raj N Kalaria; Richard J Q McNally; John T O'Brien
Increase in platelet immunoglobulin in Alzheimer's disease is normalised following cholinesterase inhibitor treatment: preliminary results.
Journal of Alzheimer's disease : JAD 2012;32(2):431-6.
2011: John-Paul Taylor; Sarah Pearce; Nicola Barnett; Janet Eyre; Michael J Firbank; Anthea Livingstone; Ian G McKeith; Urs P Mosimann; John T O'Brien
Visual hallucinations in dementia with Lewy bodies: transcranial magnetic stimulation study.
The British journal of psychiatry : the journal of mental science 2011;199(6):492-500.
2011: Sean J Colloby; Michael J Firbank; Steve W Parry; Alan J Thomas; Akshya Vasudev; John T O'Brien
White matter changes in late-life depression: a diffusion tensor imaging study.
Journal of affective disorders 2011;135(1-3):216-20.
2011: Sunil K Narayan; John T O'Brien; Brian Saxby; Gerard Stansby; Michael J Firbank; Monica Hansrani; Frances Harrington; Ian G McKeith; Gary A Ford
Plasma homocysteine and cognitive decline in older hypertensive subjects.
International psychogeriatrics / IPA 2011;23(10):1607-15.
2011: Michael J Firbank; Dipayan Mitra; Andrew Teodorczuk; Emma Teper; Andrew M Blamire; John T O'Brien
Diffusion tensor imaging in Alzheimer's disease and dementia with Lewy bodies.
Psychiatry research 2011;194(2):176-83.
2011: Sean J Colloby; Michael J Firbank; John T O'Brien; Steve W Parry; Akshya Vasudev; Alan J Thomas
Relationship of orthostatic blood pressure to white matter hyperintensities and subcortical volumes in late-life depression.
The British journal of psychiatry : the journal of mental science 2011;199(5):404-10.
2011: Harriet Quigley; Sean J Colloby; John T O'Brien
PET imaging of brain amyloid in dementia: a review.
International journal of geriatric psychiatry 2011;26(10):991-9.
2011: Giovanni B Frisoni; Bengt Winblad; John T O'Brien
Revised NIA-AA criteria for the diagnosis of Alzheimer's disease: a step forward but not yet ready for widespread clinical use.
International psychogeriatrics / IPA 2011;23(8):1191-6.
2011: Sean J Colloby; Michael J Firbank; Steve W Parry; Alan J Thomas; Akshya Vasudev; John T O'Brien
Cortical thickness and VBM-DARTEL in late-life depression.
Journal of affective disorders 2011;133(1-2):158-64.
2011: John T O'Brien; Alistair Burns
Clinical practice with anti-dementia drugs: a revised (second) consensus statement from the British Association for Psychopharmacology.
Journal of psychopharmacology (Oxford, England) 2011;25(8):997-1019.
2011: Giovanni B Frisoni; Harald Hampel; John T O'Brien; Karen Ritchie; Bengt Winblad
Revised criteria for Alzheimer's disease: what are the lessons for clinicians?
Lancet neurology 2011;10(7):598-601.
2011: Joshua S Wood; Michael J Firbank; Urs P Mosimann; John-Paul Taylor; John T O'Brien
Development of a novel FMRI compatible visual perception prototype battery to test older people with and without dementia.
Journal of geriatric psychiatry and neurology 2011;24(2):73-83.
2011: Akshya Vasudev; John T O'Brien; Maw Pin Tan; Steve W Parry; Alan J Thomas
A study of orthostatic hypotension, heart rate variability and baroreflex sensitivity in late-life depression.
Journal of affective disorders 2011;131(1-3):374-8.
2011: M J Firbank; J He; Andrew M Blamire; B Singh; P Danson; Rajesh N. Kalaria; John T O'Brien
Cerebral blood flow by arterial spin labeling in poststroke dementia.
Neurology 2011;76(17):1478-84.
2011: Christopher M Morris; Clive G Ballard; Louise Allan; Elise Rowan; Sally Stephens; Michael J Firbank; Gary A Ford; Rose Anne Kenny; John T O'Brien; Raj N Kalaria
NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors.
Neurobiology of aging 2011;32(3):554.e1-6.
2011: Alice Jordan; Julian Hughes; Mani Pakresi; Sarah Hepburn; John T O'Brien
The utility of PAINAD in assessing pain in a UK population with severe dementia.
International journal of geriatric psychiatry 2011;26(2):118-26.
2011: Sebastian Köhler; C Heather Ashton; Richard Marsh; Alan J Thomas; Nicky A Barnett; John T O'Brien
Electrophysiological changes in late life depression and their relation to structural brain changes.
International psychogeriatrics / IPA 2011;23(1):141-8.
2011: Sean J Colloby; Michael J Firbank; Sanjeet Pakrasi; Elaine K Perry; Sally Pimlott; David Wyper; Ian G McKeith; E David Williams; John T O'Brien
Alterations in nicotinic α4β2 receptor binding in vascular dementia using ¹²³I-5IA-85380 SPECT: comparison with regional cerebral blood flow.
Neurobiology of aging 2011;32(2):293-301.
2011: Sean D Smart; Michael J Firbank; John T O'Brien
Validation of automated white matter hyperintensity segmentation.
Journal of aging research 2011;2011():391783.
2011: Sunil K Narayan; John T O'Brien; Brian K Saxby; Gerard Stansby; Michael J Firbank; Monica Hansrani; Gary A Ford
Elevated plasma homocysteine is associated with increased brain atrophy rates in older subjects with mild hypertension.
Dementia and geriatric cognitive disorders 2011;31(5):341-8.
2011: Emma L Jones; Rajesh N Kalaria; Sally I Sharp; John T O'Brien; Paul T Francis; Clive G Ballard
Genetic associations of autopsy-confirmed vascular dementia subtypes.
Dementia and geriatric cognitive disorders 2011;31(4):247-53.
2010: Michael J Firbank; Sunil K Narayan; Brian K Saxby; Gary A Ford; John T O'Brien
Homocysteine is associated with hippocampal and white matter atrophy in older subjects with mild hypertension.
International psychogeriatrics / IPA 2010;22(5):804-11.
2010: Eva R Kenny; John T O'Brien; david cousins; Jonathan Richardson; Alan J Thomas; Michael J Firbank; Andrew M Blamire
Functional connectivity in late-life depression using resting-state functional magnetic resonance imaging.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2010;18(7):643-51.
2010: Sebastian Köhler; Martin P J van Boxtel; Jim van Os; Alan J Thomas; John T O'Brien; Jelle Jolles; Frans R J Verhey; Judith Allardyce
Depressive symptoms and cognitive decline in community-dwelling older adults.
Journal of the American Geriatrics Society 2010;58(5):873-9.
2010: Masafumi Ihara; Tuomo M Polvikoski; Ros Hall; Janet Y Slade; Robert H Perry; Arthur E Oakley; Elisabet Englund; John T O'Brien; Paul Geoffrey Ince; Rajesh N. Kalaria
Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies.
Acta neuropathologica 2010;119(5):579-89.
2010: Andrew Teodorczuk; Michael J Firbank; L Pantoni; A Poggesi; T Erkinjuntti; Anders Wallin; Lars-Olof Wahlund; Philip scheltens; G Waldemar; G Schrotter; J M Ferro; H Chabriat; H Bazner; M Visser; D Inzitari; John T O'Brien
Relationship between baseline white-matter changes and development of late-life depressive symptoms: 3-year results from the LADIS study.
Psychological medicine 2010;40(4):603-10.
2010: S Köhler; A J Thomas; N A Barnett; John T O'Brien
The pattern and course of cognitive impairment in late-life depression.
Psychological medicine 2010;40(4):591-602.
2010: Sean J Colloby; John P Taylor; Michael J Firbank; Ian G McKeith; E David Williams; John T O'Brien
Covariance 99mTc-exametazime SPECT patterns in Alzheimer's disease and dementia with Lewy bodies: utility in differential diagnosis.
Journal of geriatric psychiatry and neurology 2010;23(1):54-62.
2010: Sebastian Köhler; Alan J Thomas; Adrian Lloyd; Robert Barber; Osvaldo P Almeida; John T O'Brien
White matter hyperintensities, cortisol levels, brain atrophy and continuing cognitive deficits in late-life depression.
The British journal of psychiatry : the journal of mental science 2010;196(2):143-9.
2010: Michael J Firbank; Andrew M Blamire; Andrew Teodorczuk; Emma Teper; Emma J Burton; Dipayan Mitra; John T O'Brien
High resolution imaging of the medial temporal lobe in Alzheimer's disease and dementia with Lewy bodies.
Journal of Alzheimer's disease : JAD 2010;21(4):1129-40.
2010: Sean J Colloby; Elaine K Perry; Sanjeet Pakrasi; Sally L Pimlott; David Wyper; Ian G McKeith; E David Williams; John T O'Brien
Nicotinic 123I-5IA-85380 single photon emission computed tomography as a predictor of cognitive progression in Alzheimer's disease and dementia with Lewy bodies.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2010;18(1):86-90.
2009: Clive G Ballard; M Margallo-Lana; John T O'Brien; I James; R Howard; J Fossey
Top cited papers in International Psychogeriatrics: 6a. Quality of life for people with dementia living in residential and nursing home care: the impact of performance on activities of daily living, behavioral and psychological symptoms, language skills, and psychotropic drugs.
International psychogeriatrics / IPA 2009;21(6):1026-30.
2009: Jonathan Richardson; Simon R J Kerr; Fiona Shaw; Rose Anne Kenny; John T O'Brien; Alan J Thomas
A study of orthostatic hypotension in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2009;17(11):996-9.
2009: Clive G Ballard; Richard Brown; Jane Fossey; Simon Douglas; Paul Bradley; Judith Hancock; Ian A James; Edmund Juszczak; Peter Bentham; Alistair Burns; James Lindesay; Robin Jacoby; John T O'Brien; Roger Bullock; Tony Johnson; Clive Holmes; Robert Howard
Brief psychosocial therapy for the treatment of agitation in Alzheimer disease (the CALM-AD trial).
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2009;17(9):726-33.
2009: S Gauthier; John T O'Brien
Top cited papers in international psychogeriatrics: 3. Efficacy of donepezil on behavioral symptoms in patients with moderate to severe Alzheimer's disease.
International psychogeriatrics / IPA 2009;21(3):454-6.
2009: Christian Blahak; Hansjoerg Baezner; Leonardo Pantoni; A Poggesi; H Chabriat; Timo Erkinjuntti; Franz Fazekas; José M Ferro; P Langhorne; John T O'Brien; M C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Domenico Inzitari; Michael G Hennerici
Deep frontal and periventricular age related white matter changes but not basal ganglia and infratentorial hyperintensities are associated with falls: cross sectional results from the LADIS study.
Journal of neurology, neurosurgery, and psychiatry 2009;80(6):608-13.
2009: A J Thomas; P Gallagher; L J Robinson; Richard John Porter; A H Young; Ian Nicol Ferrier; John T O'Brien
A comparison of neurocognitive impairment in younger and older adults with major depression.
Psychological medicine 2009;39(5):725-33.
2009: John T O'Brien
Introduction: are dementia with Lewy bodies and Parkinson's disease dementia the same condition?
International psychogeriatrics / IPA 2009;21(2):212.
2009: Baldev Singh; John T O'Brien
When should drug treatment be started for people with dementia?
Maturitas 2009;62(3):230-4.
2009: Sophie Molloy; Thais Minett; John T O'Brien; Ian G McKeith; David J Burn
Levodopa use and sleep in patients with dementia with Lewy bodies.
Movement disorders : official journal of the Movement Disorder Society 2009;24(4):609-12.
2009: Stefan Ropele; Alexandra Seewann; Alida A Gouw; Wiesje M van der Flier; Reinhold Schmidt; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti; Philip scheltens; Lars-Olof Wahlund; Gunhild Waldemar; Hugues Chabriat; José Ferro; Michael Hennerici; John T O'Brien; Anders Wallin; Peter Langhorne; Marieke C Visser; Frederik Barkhof; Franz Fazekas
Quantitation of brain tissue changes associated with white matter hyperintensities by diffusion-weighted and magnetization transfer imaging: the LADIS (Leukoaraiosis and Disability in the Elderly) study.
Journal of magnetic resonance imaging : JMRI 2009;29(2):268-74.
2009: Julie E Simpson; Ola Hosny; Stephen B Wharton; Paul R Heath; Hazel Holden; Malee S Fernando; Fiona Matthews; Gill Forster; John T O'Brien; Robert Barber; Rajesh N. Kalaria; Carol Brayne; Pamela J Shaw; Claire E Lewis; Paul Geoffrey Ince
Microarray RNA expression analysis of cerebral white matter lesions reveals changes in multiple functional pathways.
Stroke; a journal of cerebral circulation 2009;40(2):369-75.
2009: Rosie Watson; Andrew M Blamire; John T O'Brien
Magnetic resonance imaging in lewy body dementias.
Dementia and geriatric cognitive disorders 2009;28(6):493-506.
2009: Rob Jones; Bart Sheehan; Patrick Phillips; Ed Juszczak; Jessica Adams; Ashley Baldwin; Clive G Ballard; Sube Banerjee; Bob Barber; Peter Bentham; Richard Brown; Alistair Burns; Tom Dening; David Findlay; Richard Gray; Mary Griffin; Clive Holmes; Alan Hughes; Robin Jacoby; Tony Johnson; Roy Jones; Martin Knapp; James Lindesay; Ian G McKeith; Rupert McShane; Ajay Macharouthu; John T O'Brien; Caroline Onions; Peter Passmore; James Raftery; Craig Ritchie; Rob Howard
DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT.
Trials 2009;10():57.
2009: Domenico Inzitari; Giovanni Pracucci; Anna Poggesi; Giovanna Carlucci; Frederik Barkhof; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Michael Hennerici; Peter Langhorne; John T O'Brien; Philip scheltens; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Leonardo Pantoni
Changes in white matter as determinant of global functional decline in older independent outpatients: three year follow-up of LADIS (leukoaraiosis and disability) study cohort.
BMJ (Clinical research ed.) 2009;339():b2477.
2009: Hanna Jokinen; Hely Kalska; Raija Ylikoski; Sofia Madureira; Ana Verdelho; Wiesje M van der Flier; Philip scheltens; Frederik Barkhof; Marieke C Visser; Franz Fazekas; Reinhold Schmidt; John T O'Brien; Gunhild Waldemar; Anders Wallin; Hugues Chabriat; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti
Longitudinal cognitive decline in subcortical ischemic vascular disease--the LADIS Study.
Cerebrovascular diseases (Basel, Switzerland) 2009;27(4):384-91.
2009: Hanna Jokinen; Hely Kalska; Raija Ylikoski; Sofia Madureira; Ana Verdelho; Alida Gouw; Philip scheltens; Frederik Barkhof; Marieke C Visser; Franz Fazekas; Reinhold Schmidt; John T O'Brien; Michael Hennerici; Hansjorg Baezner; Gunhild Waldemar; Anders Wallin; Hugues Chabriat; Leonardo Pantoni; Domenico Inzitari; Timo Erkinjuntti
MRI-defined subcortical ischemic vascular disease: baseline clinical and neuropsychological findings. The LADIS Study.
Cerebrovascular diseases (Basel, Switzerland) 2009;27(4):336-44.
2009: John T O'Brien; Ian G McKeith; Zuzana Walker; Klaus Tatsch; Jan Booij; Jacques Darcourt; Moritz Marquardt; Cornelia Reininger
Diagnostic accuracy of 123I-FP-CIT SPECT in possible dementia with Lewy bodies.
The British journal of psychiatry : the journal of mental science 2009;194(1):34-9.
2009: E J Burton; R Barber; E B Mukaetova-Ladinska; J Robson; Robert H Perry; E Jaros; Rajesh N. Kalaria; John T O'Brien
Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis.
Brain : a journal of neurology 2009;132(Pt 1):195-203.
2008: Sean J Colloby; Michael J Firbank; Sanjeet Pakrasi; Jim J Lloyd; Ian Driver; Ian G McKeith; E David Williams; John T O'Brien
A comparison of 99mTc-exametazime and 123I-FP-CIT SPECT imaging in the differential diagnosis of Alzheimer's disease and dementia with Lewy bodies.
International psychogeriatrics / IPA 2008;20(6):1124-40.
2008: J-P Taylor; E N Rowan; D Lett; John T O'Brien; Ian G McKeith; David J Burn
Poor attentional function predicts cognitive decline in patients with non-demented Parkinson's disease independent of motor phenotype.
Journal of neurology, neurosurgery, and psychiatry 2008;79(12):1318-23.
2008: Michael J Firbank; Robert Barber; Emma J Burton; John T O'Brien
Validation of a fully automated hippocampal segmentation method on patients with dementia.
Human brain mapping 2008;29(12):1442-9.
2008: Emma Teper; John T O'Brien
Vascular factors and depression.
International journal of geriatric psychiatry 2008;23(10):993-1000.
2008: John T O'Brien
A promising new treatment for Alzheimer's disease?
Lancet neurology 2008;7(9):768-9.
2008: Anna Poggesi; Giovanni Pracucci; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; Ana Verdelho; Michael Hennerici; Peter Langhorne; John T O'Brien; Philip scheltens; Marieke C Visser; Milita Crisby; Gunhild Waldemar; Anders Wallin; Domenico Inzitari; Leonardo Pantoni
Urinary complaints in nondisabled elderly people with age-related white matter changes: the Leukoaraiosis And DISability (LADIS) Study.
Journal of the American Geriatrics Society 2008;56(9):1638-43.
2008: Bruno Miranda; Sofia Madureira; Ana Verdelho; Jose Ferro; Leonardo Pantoni; Emilia Salvadori; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; Michael Hennerici; John T O'Brien; Philip scheltens; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; D Inzitarion
Self-perceived memory impairment and cognitive performance in an elderly independent population with age-related white matter changes.
Journal of neurology, neurosurgery, and psychiatry 2008;79(8):869-73.
2008: John T O'Brien; Sean J Colloby; Sanjeet Pakrasi; Elaine K Perry; Sally Pimlott; David Wyper; Ian G McKeith; E David Williams
Nicotinic alpha4beta2 receptor binding in dementia with Lewy bodies using 123I-5IA-85380 SPECT demonstrates a link between occipital changes and visual hallucinations.
NeuroImage 2008;40(3):1056-63.
2008: Hansjoerg Baezner; Christian Blahak; A Poggesi; Leonardo Pantoni; Domenico Inzitari; H Chabriat; Timo Erkinjuntti; Franz Fazekas; José M Ferro; P Langhorne; John T O'Brien; Philip scheltens; M C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Michael G Hennerici
Association of gait and balance disorders with age-related white matter changes: the LADIS study.
Neurology 2008;70(12):935-42.
2008: Eva R Kenny; Emma J Burton; John T O'Brien
A volumetric magnetic resonance imaging study of entorhinal cortex volume in dementia with lewy bodies. A comparison with Alzheimer's disease and Parkinson's disease with and without dementia.
Dementia and geriatric cognitive disorders 2008;26(3):218-25.
2008: John T O'Brien
Antipsychotics for people with dementia.
BMJ (Clinical research ed.) 2008;337():a602.
2008: Alan J Thomas; John T O'Brien
Depression and cognition in older adults.
Current opinion in psychiatry 2008;21(1):8-13.
2007: John T O'Brien
Role of imaging techniques in the diagnosis of dementia.
The British journal of radiology 2007;80 Spec No 2():S71-7.
2007: Julie E Simpson; Paul Geoffrey Ince; C E Higham; Catherine H Gelsthorpe; Malee S Fernando; Fiona Matthews; Gill Forster; John T O'Brien; Robert Barber; Rajesh N. Kalaria; Carol Brayne; Pamela J Shaw; Kai Stoeber; Gareth H Williams; Claire E Lewis; Stephen B Wharton
Microglial activation in white matter lesions and nonlesional white matter of ageing brains.
Neuropathology and applied neurobiology 2007;33(6):670-83.
2007: Ana Verdelho; Sofia Madureira; José M Ferro; Anna Maria Basile; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; Michael Hennerici; John T O'Brien; Leonardo Pantoni; Emilia Salvadori; Philip scheltens; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Domenico Inzitari
Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study.
Journal of neurology, neurosurgery, and psychiatry 2007;78(12):1325-30.
2007: Michael J Firbank; Emma J Burton; Robert Barber; Sally Stephens; Rose Anne Kenny; Clive G Ballard; Rajesh N. Kalaria; John T O'Brien
Medial temporal atrophy rather than white matter hyperintensities predict cognitive decline in stroke survivors.
Neurobiology of aging 2007;28(11):1664-9.
2007: Robert J Howard; Edmund Juszczak; Clive G Ballard; Peter Bentham; Richard Brown; Roger Bullock; Alistair Burns; Clive Holmes; Robin Jacoby; Tony Johnson; Martin Knapp; James Lindesay; John T O'Brien; Gordon K Wilcock; Cornelius Katona; Roy W Jones; Julia DeCesare; Michaela Rodger
Donepezil for the treatment of agitation in Alzheimer's disease.
The New England journal of medicine 2007;357(14):1382-92.
2007: John-Paul Taylor; Sean J Colloby; Ian G McKeith; David J Burn; David Williams; Jim Patterson; John T O'Brien
Cholinesterase inhibitor use does not significantly influence the ability of 123I-FP-CIT imaging to distinguish Alzheimer's disease from dementia with Lewy bodies.
Journal of neurology, neurosurgery, and psychiatry 2007;78(10):1069-71.
2007: Alan J Thomas; Christopher Morris; Sue Davis; Elizabeth Jackson; Richard Harrison; John T O'Brien
Soluble cell adhesion molecules in late-life depression.
International psychogeriatrics / IPA 2007;19(5):914-20.
2007: Andrew Teodorczuk; John T O'Brien; Michael J Firbank; Leonardo Pantoni; Anna Poggesi; Timo Erkinjuntti; Anders Wallin; Lars-Olof Wahlund; Alida A Gouw; Gunhild Waldemar; Reinhold Schmidt; José M Ferro; Hugues Chabriat; H Bäzner; Domenico Inzitari
White matter changes and late-life depressive symptoms: longitudinal study.
The British journal of psychiatry : the journal of mental science 2007;191():212-7.
2007: Bruno Dubois; Howard H Feldman; Claudia Jacova; Steven T DeKosky; Pascale Barberger-Gateau; Jeffrey L Cummings; André Delacourte; Douglas Galasko; S Gauthier; Gregory A Jicha; Kenichi Meguro; John T O'Brien; Florence Pasquier; Philippe Robert; Martin N Rossor; Steven Salloway; Yaakov Stern; Pieter J Visser; Philip scheltens
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria.
Lancet neurology 2007;6(8):734-46.
2007: Julie E Simpson; Malee S Fernando; L Clark; Paul Geoffrey Ince; Fiona Matthews; Gill Forster; John T O'Brien; Robert Barber; Rajesh N. Kalaria; Carol Brayne; Pamela J Shaw; Claire E Lewis; Stephen B Wharton
White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses.
Neuropathology and applied neurobiology 2007;33(4):410-9.
2007: Michael J Firbank; Andrew M Blamire; Mani S Krishnan; Andrew Teodorczuk; Philip English; Anil Gholkar; Roger M Harrison; John T O'Brien
Diffusion tensor imaging in dementia with Lewy bodies and Alzheimer's disease.
Psychiatry research 2007;155(2):135-45.
2007: Sanjeet Pakrasi; Sean J Colloby; Michael J Firbank; Elaine K Perry; David Wyper; Jonathan Owens; Ian G McKeith; E David Williams; John T O'Brien
Muscarinic acetylcholine receptor status in Alzheimer's disease assessed using (R, R) 123I-QNB SPECT.
Journal of neurology 2007;254(7):907-13.
2007: Michael J Firbank; Rebecca M Wiseman; Emma J Burton; Brian Saxby; John T O'Brien; Gary A Ford
Brain atrophy and white matter hyperintensity change in older adults and relationship to blood pressure. Brain atrophy, WMH change and blood pressure.
Journal of neurology 2007;254(6):713-21.
2007: John T O'Brien
Introduction: for debate: should neuroimaging be a routine investigation in all cases of suspected dementia?
International psychogeriatrics / IPA 2007;19(3):525-6.
2007: Frauke Boddy; Elise Rowan; Debbie Lett; John T O'Brien; Ian G McKeith; David J Burn
Subjectively reported sleep quality and excessive daytime somnolence in Parkinson's disease with and without dementia, dementia with Lewy bodies and Alzheimer's disease.
International journal of geriatric psychiatry 2007;22(6):529-35.
2007: Charlotte Ryberg; Egill Rostrup; M B Stegmann; Frederik Barkhof; Philip scheltens; E C W van Straaten; Franz Fazekas; Reinhold Schmidt; José M Ferro; Hansjoerg Baezner; Timo Erkinjuntti; Hanna Jokinen; Lars-Olof Wahlund; John T O'Brien; Anna Maria Basile; Leonardo Pantoni; Domenico Inzitari; Gunhild Waldemar
Clinical significance of corpus callosum atrophy in a mixed elderly population.
Neurobiology of aging 2007;28(6):955-63.
2007: Clive G Ballard; Katy Chalmers; C Todd; Ian G McKeith; John T O'Brien; Gordon K Wilcock; Seth Love; Elaine K Perry
Cholinesterase inhibitors reduce cortical Abeta in dementia with Lewy bodies.
Neurology 2007;68(20):1726-9.
2007: Michael J Firbank; Andrew M Blamire; Mani S Krishnan; Andrew Teodorczuk; Philip English; Anil Gholkar; Roger Harrison; John T O'Brien
Atrophy is associated with posterior cingulate white matter disruption in dementia with Lewy bodies and Alzheimer's disease.
NeuroImage 2007;36(1):1-7.
2007: Ian G McKeith; John T O'Brien; Zuzana Walker; Klaus Tatsch; Jan Booij; Jacques Darcourt; Alessandro Padovani; Raffaele Giubbini; Ubaldo Bonuccelli; Duccio Volterrani; Clive Holmes; Paul Kemp; Naji Tabet; Ines Meyer; Cornelia Reininger
Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study.
Lancet neurology 2007;6(4):305-13.
2007: John T O'Brien; Sean J Colloby; Sanjeet Pakrasi; Elaine K Perry; Sally Pimlott; David Wyper; Ian G McKeith; E David Williams
Alpha4beta2 nicotinic receptor status in Alzheimer's disease using 123I-5IA-85380 single-photon-emission computed tomography.
Journal of neurology, neurosurgery, and psychiatry 2007;78(4):356-62.
2007: Domenico Inzitari; Michela Simoni; Giovanni Pracucci; Anna Poggesi; Anna Maria Basile; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Michael Hennerici; Peter Langhorne; John T O'Brien; Frederik Barkhof; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Leonardo Pantoni
Risk of rapid global functional decline in elderly patients with severe cerebral age-related white matter changes: the LADIS study.
Archives of internal medicine 2007;167(1):81-8.
2007: Elise Rowan; Ian G McKeith; Brian Saxby; John T O'Brien; David J Burn; Urs P Mosimann; Jane Newby; Sarah Daniel; Jonathan Sanders; Keith Wesnes
Effects of donepezil on central processing speed and attentional measures in Parkinson's disease with dementia and dementia with Lewy bodies.
Dementia and geriatric cognitive disorders 2007;23(3):161-7.
2007: Richard John Porter; Peter Gallagher; John T O'Brien
Effects of rapid tryptophan depletion on salivary cortisol in older people recovered from depression, and the healthy elderly.
Journal of psychopharmacology (Oxford, England) 2007;21(1):71-5.
2006: Clive G Ballard; Iryna Ziabreva; Robert H Perry; Jan Petter Larsen; John T O'Brien; Ian G McKeith; Elaine K Perry; Dag Aarsland
Differences in neuropathologic characteristics across the Lewy body dementia spectrum.
Neurology 2006;67(11):1931-4.
2006: John T O'Brien
NICE and anti-dementia drugs: a triumph of health economics over clinical wisdom?
Lancet neurology 2006;5(12):994-6.
2006: SA Molloy; Elise Rowan; John T O'Brien; Ian G McKeith; K Wesnes; David J Burn
Effect of levodopa on cognitive function in Parkinson's disease with and without dementia and dementia with Lewy bodies.
Journal of neurology, neurosurgery, and psychiatry 2006;77(12):1323-8.
2006: Alistair Burns; John T O'Brien; Sophie Auriacombe; Clive G Ballard; Karl Broich; Roger Bullock; Howard Feldman; Gary Ford; Martin Knapp; Andrew McCaddon; Stephen Iliffe; Claudia Jacova; Roy Jones; Sean Lennon; Ian G McKeith; Jean-Marc Orgogozo; Nitin Purandare; Mervyn Richardson; Craig Ritchie; Alan Thomas; James Warner; Gordon K Wilcock; David Wilkinson
Clinical practice with anti-dementia drugs: a consensus statement from British Association for Psychopharmacology.
Journal of psychopharmacology (Oxford, England) 2006;20(6):732-55.
2006: Sean J Colloby; Sanjeet Pakrasi; Michael J Firbank; Elaine K Perry; Margaret A Piggott; Jonathan Owens; David Wyper; Ian G McKeith; David J Burn; E David Williams; John T O'Brien
In vivo SPECT imaging of muscarinic acetylcholine receptors using (R,R) 123I-QNB in dementia with Lewy bodies and Parkinson's disease dementia.
NeuroImage 2006;33(2):423-9.
2006: Emma J Burton; Ian G McKeith; David J Burn; Michael J Firbank; John T O'Brien
Progression of white matter hyperintensities in Alzheimer disease, dementia with lewy bodies, and Parkinson disease dementia: a comparison with normal aging.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006;14(10):842-9.
2006: John T O'Brien; Michael J Firbank; Mani S Krishnan; E C W van Straaten; Wiesje M van der Flier; Katja Petrovic; Leonardo Pantoni; Michela Simoni; Timo Erkinjuntti; Anders Wallin; Lars-Olof Wahlund; Domenico Inzitari
White matter hyperintensities rather than lacunar infarcts are associated with depressive symptoms in older people: the LADIS study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006;14(10):834-41.
2006: Mani S Krishnan; John T O'Brien; Michael J Firbank; Leonardo Pantoni; Giovanna Carlucci; Timo Erkinjuntti; Anders Wallin; Lars-Olof Wahlund; Philip scheltens; E C W van Straaten; Domenico Inzitari
Relationship between periventricular and deep white matter lesions and depressive symptoms in older people. The LADIS Study.
International journal of geriatric psychiatry 2006;21(10):983-9.
2006: John T O'Brien
Vascular cognitive impairment.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006;14(9):724-33.
2006: Ronald C. Petersen; John T O'Brien
Mild cognitive impairment should be considered for DSM-V.
Journal of geriatric psychiatry and neurology 2006;19(3):147-54.
2006: Sanjeet Pakrasi; Alan Thomas; Urs P Mosimann; david cousins; Debbie Lett; David J Burn; John T O'Brien; Ian G McKeith
Cholinesterase inhibitors in advanced Dementia with Lewy bodies: increase or stop?
International journal of geriatric psychiatry 2006;21(8):719-21.
2006: Leonardo Pantoni; Anna Poggesi; Anna Maria Basile; Giovanni Pracucci; Frederik Barkhof; Hugues Chabriat; Timo Erkinjuntti; José M Ferro; Michael Hennerici; John T O'Brien; Reinhold Schmidt; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Domenico Inzitari
Leukoaraiosis predicts hidden global functioning impairment in nondisabled older people: the LADIS (Leukoaraiosis and Disability in the Elderly) Study.
Journal of the American Geriatrics Society 2006;54(7):1095-101.
2006: E Coulthard; Michael J Firbank; Philip English; J Welch; Daniel Birchall; John T O'Brien; T D Griffiths
Proton magnetic resonance spectroscopy in frontotemporal dementia.
Journal of neurology 2006;253(7):861-8.
2006: Ian G McKeith; Elise Rowan; Kristina Askew; Anitha Naidu; Louise Allan; Nicky Barnett; Debbie Lett; Urs P Mosimann; David J Burn; John T O'Brien
More severe functional impairment in dementia with lewy bodies than Alzheimer disease is related to extrapyramidal motor dysfunction.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006;14(7):582-8.
2006: Alan J Thomas; M Hendriksen; Margaret A Piggott; Ian Nicol Ferrier; Elaine K Perry; Paul Ince; John T O'Brien
A study of the serotonin transporter in the prefrontal cortex in late-life depression and Alzheimer's disease with and without depression.
Neuropathology and applied neurobiology 2006;32(3):296-303.
2006: Malee S Fernando; Julie E Simpson; Fiona Matthews; Carol Brayne; Claire E Lewis; Robert Barber; Rajesh N. Kalaria; Gill Forster; Filomena Esteves; Stephen B Wharton; Pamela J Shaw; John T O'Brien; Paul Geoffrey Ince
White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury.
Stroke; a journal of cerebral circulation 2006;37(6):1391-8.
2006: David J Burn; Elise Rowan; Louise M Allan; SA Molloy; John T O'Brien; Ian G McKeith
Motor subtype and cognitive decline in Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies.
Journal of neurology, neurosurgery, and psychiatry 2006;77(5):585-9.
2006: John T O'Brien
Depression and comorbidity.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006;14(3):187-90.
2006: Urs P Mosimann; Elise Rowan; Cassie E Partington; Daniel Collerton; Elizabeth Littlewood; John T O'Brien; David J Burn; Ian G McKeith
Characteristics of visual hallucinations in Parkinson disease dementia and dementia with lewy bodies.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006;14(2):153-60.
2006: Sofia Madureira; Ana Verdelho; Jose Ferro; Anna Maria Basile; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; Michael Hennerici; John T O'Brien; Leonardo Pantoni; Emilia Salvadori; Philip scheltens; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Domenico Inzitari
Development of a neuropsychological battery for the Leukoaraiosis and Disability in the Elderly Study (LADIS): experience and baseline data.
Neuroepidemiology 2006;27(2):101-16.
2006: Anna Maria Basile; Leonardo Pantoni; Giovanni Pracucci; Kjell Asplund; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Michael Hennerici; John T O'Brien; Philip scheltens; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Domenico Inzitari
Age, hypertension, and lacunar stroke are the major determinants of the severity of age-related white matter changes. The LADIS (Leukoaraiosis and Disability in the Elderly) Study.
Cerebrovascular diseases (Basel, Switzerland) 2006;21(5-6):315-22.
2005: Ian G McKeith; dennis dickson; J Lowe; M Emre; John T O'Brien; H Feldman; Jeffrey L Cummings; J E Duda; Carol F Lippa; Elaine K Perry; Dag Aarsland; Heii Arai; Clive G Ballard; Bradley Boeve; David J Burn; D Costa; T Del Ser; Bruno Dubois; Douglas Galasko; S Gauthier; Christopher G Goetz; E Gomez-Tortosa; G Halliday; Lawrence A Hansen; John Hardy; Takeshi Iwatsubo; Rajesh N. Kalaria; Daniel Kaufer; R A Kenny; Amos D Korczyn; Kenji Kosaka; Virginia M-Y Lee; Andrew J Lees; I Litvan; E Londos; Oscar L Lopez; Satoshi Minoshima; Yoshikuni Mizuno; J A Molina; E B Mukaetova-Ladinska; Florence Pasquier; Robert H Perry; J B Schulz; John Q Trojanowski; Masahito Yamada
Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium.
Neurology 2005;65(12):1863-72.
2005: Emma J Burton; Ian G McKeith; David J Burn; John T O'Brien
Brain atrophy rates in Parkinson's disease with and without dementia using serial magnetic resonance imaging.
Movement disorders : official journal of the Movement Disorder Society 2005;20(12):1571-6.
2005: Michael J Firbank; SA Molloy; Ian G McKeith; David J Burn; John T O'Brien
Longitudinal change in 99mTcHMPAO cerebral perfusion SPECT in Parkinson's disease over one year.
Journal of neurology, neurosurgery, and psychiatry 2005;76(10):1448-51.
2005: Lars S Rasmussen; John T O'Brien; JH Silverstein; T W Johnson; Volkert D Siersma; Jaume Canet; J Jolles; Chris D Hanning; HM Kuipers; Hanne Abildstrom; A Papaioannou; J Raeder; A Yli-Hankala; J R Sneyd; L Munoz; Jakob T Moller
Is peri-operative cortisol secretion related to post-operative cognitive dysfunction?
Acta anaesthesiologica Scandinavica 2005;49(9):1225-31.
2005: Sean J Colloby; E David Williams; David J Burn; Jim J Lloyd; Ian G McKeith; John T O'Brien
Progression of dopaminergic degeneration in dementia with Lewy bodies and Parkinson's disease with and without dementia assessed using 123I-FP-CIT SPECT.
European journal of nuclear medicine and molecular imaging 2005;32(10):1176-85.
2005: S Molloy; Ian G McKeith; John T O'Brien; David J Burn
The role of levodopa in the management of dementia with Lewy bodies.
Journal of neurology, neurosurgery, and psychiatry 2005;76(9):1200-3.
2005: Thais Minett; Jennie L Dean; Michael J Firbank; Philip English; John T O'Brien
Subjective memory complaints, white-matter lesions, depressive symptoms, and cognition in elderly patients.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005;13(8):665-71.
2005: Michael J Firbank; David J Burn; Ian G McKeith; John T O'Brien
Longitudinal study of cerebral blood flow SPECT in Parkinson's disease with dementia, and dementia with Lewy bodies.
International journal of geriatric psychiatry 2005;20(8):776-82.
2005: John T O'Brien; Michael J Firbank; Urs P Mosimann; David J Burn; Ian G McKeith
Change in perfusion, hallucinations and fluctuations in consciousness in dementia with Lewy bodies.
Psychiatry research 2005;139(2):79-88.
2005: Michael J Firbank; John T O'Brien; Sanjeet Pakrasi; Leonardo Pantoni; Michela Simoni; Timo Erkinjuntti; Anders Wallin; Lars-Olof Wahlund; Ilse van Straaten; Domenico Inzitari
White matter hyperintensities and depression--preliminary results from the LADIS study.
International journal of geriatric psychiatry 2005;20(7):674-9.
2005: Richard John Porter; Andrew J Phipps; Peter Gallagher; Ailsa Scott; Pamela S Stevenson; John T O'Brien
Effects of acute tryptophan depletion on mood and cognitive functioning in older recovered depressed subjects.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005;13(7):607-15.
2005: Urs P Mosimann; René Martin Mueri; David J Burn; Jacques Felblinger; John T O'Brien; Ian G McKeith
Saccadic eye movement changes in Parkinson's disease dementia and dementia with Lewy bodies.
Brain : a journal of neurology 2005;128(Pt 6):1267-76.
2005: Dag Aarsland; Robert H Perry; Jan Petter Larsen; Ian G McKeith; John T O'Brien; Elaine K Perry; David J Burn; Clive G Ballard
Neuroleptic sensitivity in Parkinson's disease and parkinsonian dementias.
The Journal of clinical psychiatry 2005;66(5):633-7.
2005: Clive G Ballard; Marisa Margallo-Lana; Edmund Juszczak; Simon Douglas; Alan Swann; Alan Thomas; John T O'Brien; Anna Everratt; Stuart Sadler; Clare Maddison; Lesley Lee; Carol Bannister; Ruth Elvish; Robin Jacoby
Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: randomised double blind placebo controlled trial.
BMJ (Clinical research ed.) 2005;330(7496):874.
2005: C W C Tam; Emma J Burton; Ian G McKeith; David J Burn; John T O'Brien
Temporal lobe atrophy on MRI in Parkinson disease with dementia: a comparison with Alzheimer disease and dementia with Lewy bodies.
Neurology 2005;64(5):861-5.
2005: Sanjeet Pakrasi; John T O'Brien
Emission tomography in dementia.
Nuclear medicine communications 2005;26(3):189-96.
2005: John T O'Brien
Dementia associated with psychiatric disorders.
International psychogeriatrics / IPA 2005;17 Suppl 1():S207-21.
2005: Alan J Thomas; Sue Davis; Christopher Morris; Elizabeth Jackson; Richard Harrison; John T O'Brien
Increase in interleukin-1beta in late-life depression.
The American journal of psychiatry 2005;162(1):175-7.
2005: Alan Thomas; Clive G Ballard; Rose Anne Kenny; John T O'Brien; Arthur Oakley; Rajesh N. Kalaria
Correlation of entorhinal amyloid with memory in Alzheimer's and vascular but not Lewy body dementia.
Dementia and geriatric cognitive disorders 2005;19(2-3):57-60.
2005: Leonardo Pantoni; Anna Maria Basile; Giovanni Pracucci; Kjell Asplund; daryoush heydari; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; José M Ferro; Michael Hennerici; John T O'Brien; Philip scheltens; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Domenico Inzitari
Impact of age-related cerebral white matter changes on the transition to disability -- the LADIS study: rationale, design and methodology.
Neuroepidemiology 2005;24(1-2):51-62.
2004: Urs P Mosimann; G Mather; K A Wesnes; John T O'Brien; David J Burn; Ian G McKeith
Visual perception in Parkinson disease dementia and dementia with Lewy bodies.
Neurology 2004;63(11):2091-6.
2004: Rebecca M Wiseman; Brian Saxby; Emma J Burton; Robert Barber; Gary A Ford; John T O'Brien
Hippocampal atrophy, whole brain volume, and white matter lesions in older hypertensive subjects.
Neurology 2004;63(10):1892-7.
2004: Michael J Firbank; Adrian J Lloyd; Nicol Ferrier; John T O'Brien
A volumetric study of MRI signal hyperintensities in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2004;12(6):606-12.
2004: Sean J Colloby; John T O'Brien; John D Fenwick; Michael J Firbank; David J Burn; Ian G McKeith; E David Williams
The application of statistical parametric mapping to 123I-FP-CIT SPECT in dementia with Lewy bodies, Alzheimer's disease and Parkinson's disease.
NeuroImage 2004;23(3):956-66.
2004: John T O'Brien; Adrian Lloyd; Ian G McKeith; Anil Gholkar; Nicol Ferrier
A longitudinal study of hippocampal volume, cortisol levels, and cognition in older depressed subjects.
The American journal of psychiatry 2004;161(11):2081-90.
2004: Clive G Ballard; Christopher M Morris; H Rao; John T O'Brien; R Barber; Sally Stephens; Elise Rowan; A Gibson; Rajesh N. Kalaria; Rose Anne Kenny
APOE epsilon4 and cognitive decline in older stroke patients with early cognitive impairment.
Neurology 2004;63(8):1399-402.
2004: Clive G Ballard; Emma J Burton; Robert Barber; Sally Stephens; Rose Anne Kenny; Rajesh N. Kalaria; John T O'Brien
NINDS AIREN neuroimaging criteria do not distinguish stroke patients with and without dementia.
Neurology 2004;63(6):983-8.
2004: Martina Ballmaier; John T O'Brien; Emma J Burton; Paul M Thompson; David E Rex; Owen Phillips; Ian G McKeith; Heather DeLuca; Arthur W Toga
Comparing gray matter loss profiles between dementia with Lewy bodies and Alzheimer's disease using cortical pattern matching: diagnosis and gender effects.
NeuroImage 2004;23(1):325-35.
2004: Sean J Colloby; John T O'Brien
Functional imaging in Parkinson's disease and dementia with Lewy bodies.
Journal of geriatric psychiatry and neurology 2004;17(3):158-63.
2004: Malee S Fernando; John T O'Brien; Robert H Perry; P English; Gill Forster; William McMeekin; J Y Slade; A Golkhar; Fiona Matthews; Robert Barber; Rajesh N. Kalaria; Paul Geoffrey Ince
Comparison of the pathology of cerebral white matter with post-mortem magnetic resonance imaging (MRI) in the elderly brain.
Neuropathology and applied neurobiology 2004;30(4):385-95.
2004: Rose Anne Kenny; F E Shaw; John T O'Brien; Philip scheltens; Rajesh N. Kalaria; Clive G Ballard
Carotid sinus syndrome is common in dementia with Lewy bodies and correlates with deep white matter lesions.
Journal of neurology, neurosurgery, and psychiatry 2004;75(7):966-71.
2004: John T O'Brien; Sean J Colloby; John D Fenwick; E David Williams; Michael J Firbank; David J Burn; Dag Aarsland; Ian G McKeith
Dopamine transporter loss visualized with FP-CIT SPECT in the differential diagnosis of dementia with Lewy bodies.
Archives of neurology 2004;61(6):919-25.
2004: Adrian J Lloyd; Ian Nicol Ferrier; Robert Barber; Anil Gholkar; Allan H Young; John T O'Brien
Hippocampal volume change in depression: late- and early-onset illness compared.
The British journal of psychiatry : the journal of mental science 2004;184():488-95.
2004: Michelle Hendricksen; Alan J Thomas; Ian Nicol Ferrier; Paul Ince; John T O'Brien
Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depression.
The American journal of psychiatry 2004;161(6):1096-102.
2004: Emma J Burton; Rose Anne Kenny; John T O'Brien; Sally Stephens; Michael Bradbury; Elise Rowan; Rajesh N. Kalaria; Michael J Firbank; Keith Wesnes; Clive G Ballard
White matter hyperintensities are associated with impairment of memory, attention, and global cognitive performance in older stroke patients.
Stroke; a journal of cerebral circulation 2004;35(6):1270-5.
2004: Clive G Ballard; Robin Jacoby; Teodoro del Ser; M Nadeem Khan; David G Munoz; Clive Holmes; Zsuzanna Nagy; Elaine K Perry; Catherine Joachim; Evelyn Jaros; John T O'Brien; Robert H Perry; Ian G McKeith
Neuropathological substrates of psychiatric symptoms in prospectively studied patients with autopsy-confirmed dementia with lewy bodies.
The American journal of psychiatry 2004;161(5):843-9.
2004: Alan J Thomas; Rajesh N. Kalaria; John T O'Brien
Depression and vascular disease: what is the relationship?
Journal of affective disorders 2004;79(1-3):81-95.
2004: Emma J Burton; Ian G McKeith; David J Burn; E David Williams; John T O'Brien
Cerebral atrophy in Parkinson's disease with and without dementia: a comparison with Alzheimer's disease, dementia with Lewy bodies and controls.
Brain : a journal of neurology 2004;127(Pt 4):791-800.
2004: Alan J Thomas; Sue Davis; Ian Nicol Ferrier; Rajesh N. Kalaria; John T O'Brien
Elevation of cell adhesion molecule immunoreactivity in the anterior cingulate cortex in bipolar disorder.
Biological psychiatry 2004;55(6):652-5.
2004: Sean M Paling; E David Williams; Robert Barber; Emma J Burton; Bill Crum; Nick C Fox; John T O'Brien
The application of serial MRI analysis techniques to the study of cerebral atrophy in late-onset dementia.
Medical image analysis 2004;8(1):69-79.
2004: Clive G Ballard; Alan Thomas; Jane Fossey; Lesley Lee; Robin Jacoby; Marisa M Lana; Carol Bannister; Rupert McShane; Alan Swann; Ed Juszczak; John T O'Brien
A 3-month, randomized, placebo-controlled, neuroleptic discontinuation study in 100 people with dementia: the neuropsychiatric inventory median cutoff is a predictor of clinical outcome.
The Journal of clinical psychiatry 2004;65(1):114-9.
2004: Ian G McKeith; Jacobo E Mintzer; Dag Aarsland; David J Burn; Helen Chiu; Jiska Cohen-Mansfield; dennis dickson; Bruno Dubois; John E Duda; Howard Feldman; S Gauthier; Glenda Halliday; Brian A Lawlor; Carol F Lippa; Oscar L Lopez; João Carlos Machado; John T O'Brien; Jeremy Playfer; Wayne Reid
Dementia with Lewy bodies.
Lancet neurology 2004;3(1):19-28.
2003: david cousins; Emma J Burton; David J Burn; Anil Gholkar; Ian G McKeith; John T O'Brien
Atrophy of the putamen in dementia with Lewy bodies but not Alzheimer's disease: an MRI study.
Neurology 2003;61(9):1191-5.
2003: Dawn Potkins; Pat Myint; Carol Bannister; George Tadros; Ramilgan Chithramohan; Alan Swann; John T O'Brien; Jane Fossey; Eugenie George; Clive G Ballard; Marisa Margallo-Lana
Language impairment in dementia: impact on symptoms and care needs in residential homes.
International journal of geriatric psychiatry 2003;18(11):1002-6.
2003: M J Firbank; T Minett; John T O'Brien
Changes in DWI and MRS associated with white matter hyperintensities in elderly subjects.
Neurology 2003;61(7):950-4.
2003: Michael J Firbank; Sean J Colloby; David J Burn; Ian G McKeith; John T O'Brien
Regional cerebral blood flow in Parkinson's disease with and without dementia.
NeuroImage 2003;20(2):1309-19.
2003: S Pakrasi; E B Mukaetova-Ladinska; Ian G McKeith; John T O'Brien
Clinical predictors of response to Acetyl Cholinesterase Inhibitors: experience from routine clinical use in Newcastle.
International journal of geriatric psychiatry 2003;18(10):879-86.
2003: David J Burn; John T O'Brien
Use of functional imaging in Parkinsonism and dementia.
Movement disorders : official journal of the Movement Disorder Society 2003;18 Suppl 6():S88-95.
2003: Alan J Thomas; John T O'Brien; Robert Barber; William McMeekin; Robert H Perry
A neuropathological study of periventricular white matter hyperintensities in major depression.
Journal of affective disorders 2003;76(1-3):49-54.
2003: David J Burn; Elise Rowan; Thais Minett; Jonathan Sanders; Pat Myint; Jonathon Richardson; Alan Thomas; Jane Newby; Jenny Reid; John T O'Brien; Ian G McKeith
Extrapyramidal features in Parkinson's disease with and without dementia and dementia with Lewy bodies: A cross-sectional comparative study.
Movement disorders : official journal of the Movement Disorder Society 2003;18(8):884-9.
2003: John T O'Brien; Alan Thomas; Philip English; Robert H Perry; Evelyn Jaros
A prospectively studied clinicopathological case of 'vascular depression'.
International journal of geriatric psychiatry 2003;18(7):656-7.
2003: Janet Grace; John T O'Brien
Association of life events and psychosocial factors with early but not late onset depression in the elderly: implications for possible differences in aetiology.
International journal of geriatric psychiatry 2003;18(6):473-8.
2003: Osvaldo P Almeida; Emma J Burton; N Ferrier; Ian G McKeith; John T O'Brien
Depression with late onset is associated with right frontal lobe atrophy.
Psychological medicine 2003;33(4):675-81.
2003: Giorgos Karas; E J Burton; Serge A R B Rombouts; Ronald A van Schijndel; John T O'Brien; Philip scheltens; Ian G McKeith; D Williams; Clive G Ballard; Frederik Barkhof
A comprehensive study of gray matter loss in patients with Alzheimer's disease using optimized voxel-based morphometry.
NeuroImage 2003;18(4):895-907.
2003: Kirsty K O'Brien; Brian Saxby; Clive G Ballard; Jan Grace; Frances Harrington; Gary A Ford; John T O'Brien; Alan G Swan; Andrew F Fairbairn; Keith Wesnes; Teodoro del Ser; James A Edwardson; Christopher M Morris; Ian G McKeith
Regulation of attention and response to therapy in dementia by butyrylcholinesterase.
Pharmacogenetics 2003;13(4):231-9.
2003: Margaret A Piggott; Jonathan Owens; John T O'Brien; Sean J Colloby; John D Fenwick; David Wyper; Evelyn Jaros; Mary Johnson; Robert H Perry; Elaine K Perry
Muscarinic receptors in basal ganglia in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease.
Journal of chemical neuroanatomy 2003;25(3):161-73.
2003: John T O'Brien; Timo Erkinjuntti; Barry Reisberg; Gustavo Roman; Tohru Sawada; Leonardo Pantoni; John V Bowler; Clive G Ballard; Charles DeCarli; Philip B Gorelick; kenneth rockwood; Alistair Burns; S Gauthier; Steven T DeKosky
Vascular cognitive impairment.
Lancet neurology 2003;2(2):89-98.
2003: John T O'Brien
Behavioral symptoms in vascular cognitive impairment and vascular dementia.
International psychogeriatrics / IPA 2003;15 Suppl 1():133-8.
2003: John T O'Brien; Barry Reisberg; Timo Erkinjuntti
Vascular burden of the brain.
International psychogeriatrics / IPA 2003;15 Suppl 1():7-10.
2003: Daniel Collerton; David J Burn; Ian G McKeith; John T O'Brien
Systematic review and meta-analysis show that dementia with Lewy bodies is a visual-perceptual and attentional-executive dementia.
Dementia and geriatric cognitive disorders 2003;16(4):229-37.
2003: Emma Burton; Clive G Ballard; Sally Stephens; Rose Anne Kenny; Rajesh N. Kalaria; Robert Barber; John T O'Brien
Hyperintensities and fronto-subcortical atrophy on MRI are substrates of mild cognitive deficits after stroke.
Dementia and geriatric cognitive disorders 2003;16(2):113-8.
2003: Osvaldo P Almeida; Emma J Burton; Ian G McKeith; Anil Gholkar; David J Burn; John T O'Brien
MRI study of caudate nucleus volume in Parkinson's disease with and without dementia with Lewy bodies and Alzheimer's disease.
Dementia and geriatric cognitive disorders 2003;16(2):57-63.
2003: Clive G Ballard; Sally Stephens; Rose Anne Kenny; Rajesh N. Kalaria; Martin Tovee; John T O'Brien
Profile of neuropsychological deficits in older stroke survivors without dementia.
Dementia and geriatric cognitive disorders 2003;16(1):52-6.
2003: Ian G McKeith; David J Burn; Clive G Ballard; Daniel Collerton; Evelyn Jaros; Christopher M Morris; Andrew McLaren; Elaine K Perry; Robert H Perry; Margaret A Piggott; John T O'Brien
Dementia with Lewy bodies.
Seminars in clinical neuropsychiatry 2003;8(1):46-57.
2003: Richard John Porter; Brian S Lunn; John T O'Brien
Effects of acute tryptophan depletion on cognitive function in Alzheimer's disease and in the healthy elderly.
Psychological medicine 2003;33(1):41-9.
2003: Alan J Thomas; Robert H Perry; Rajesh N. Kalaria; Arthur Oakley; William McMeekin; John T O'Brien
Neuropathological evidence for ischemia in the white matter of the dorsolateral prefrontal cortex in late-life depression.
International journal of geriatric psychiatry 2003;18(1):7-13.
2002: Clive G Ballard; Dag Aarsland; Ian G McKeith; John T O'Brien; Alistair Gray; Francesca Cormack; David J Burn; T Cassidy; R Starfeldt; Jan Petter Larsen; R Brown; M Tovee
Fluctuations in attention: PD dementia vs DLB with parkinsonism.
Neurology 2002;59(11):1714-20.
2002: Andrew J Phipps; John T O'Brien
Memory clinics and clinical governance--a UK perspective.
International journal of geriatric psychiatry 2002;17(12):1128-32.
2002: John T O'Brien; Sean Lilienfeld
Relevant clinical outcomes in probable vascular dementia and Alzheimer's disease with cerebrovascular disease.
Journal of the neurological sciences 2002;203-204():41-8.
2002: John T O'Brien; Rebecca M Wiseman; Emma J Burton; Bob Barber; Keith Wesnes; Brian Saxby; Gary A Ford
Cognitive associations of subcortical white matter lesions in older people.
Annals of the New York Academy of Sciences 2002;977():436-44.
2002: Alan J Thomas; Robert H Perry; Robert Barber; Rajesh N. Kalaria; John T O'Brien
Pathologies and pathological mechanisms for white matter hyperintensities in depression.
Annals of the New York Academy of Sciences 2002;977():333-9.
2002: Clive G Ballard; Sally Stephens; Andrew McLaren; Keith Wesnes; Rose Anne Kenny; Emma Burton; John T O'Brien; Rajesh N. Kalaria
Neuropsychological deficits in older stroke patients.
Annals of the New York Academy of Sciences 2002;977():179-82.
2002: Kath Lowery; Clive G Ballard; Helen Rodgers; Andrew McLaren; John T O'Brien; Elise Rowan; Sally Stephens
Cognitive decline in a prospectively studied group of stroke survivors, with a particular emphasis on the >75's.
Age and ageing 2002;31 Suppl 3():24-7.
2002: Isaac Schweitzer; Virginia Tuckwell; John T O'Brien; David Ames
Is late onset depression a prodrome to dementia?
International journal of geriatric psychiatry 2002;17(11):997-1005.
2002: S Davis; A Thomas; Robert H Perry; A Oakley; Rajesh N. Kalaria; John T O'Brien
Glial fibrillary acidic protein in late life major depressive disorder: an immunocytochemical study.
Journal of neurology, neurosurgery, and psychiatry 2002;73(5):556-60.
2002: Emma J Burton; Giorgos Karas; Sean M Paling; Robert Barber; E David Williams; Clive G Ballard; Ian G McKeith; Philip scheltens; Frederik Barkhof; John T O'Brien
Patterns of cerebral atrophy in dementia with Lewy bodies using voxel-based morphometry.
NeuroImage 2002;17(2):618-30.
2002: Clive G Ballard; Jennifer A Court; Margaret A Piggott; Mary Johnson; John T O'Brien; Ian G McKeith; Clive Holmes; Peter Lantos; Evelyn Jaros; Robert H Perry; Elaine K Perry
Disturbances of consciousness in dementia with Lewy bodies associated with alteration in nicotinic receptor binding in the temporal cortex.
Consciousness and cognition 2002;11(3):461-74.
2002: Margaret A Piggott; Jonathan Owens; John T O'Brien; Sean Paling; David Wyper; John Fenwick; Mary Johnson; Robert H Perry; Elaine K Perry
Comparative distribution of binding of the muscarinic receptor ligands pirenzepine, AF-DX 384, (R,R)-I-QNB and (R,S)-I-QNB to human brain.
Journal of chemical neuroanatomy 2002;24(3):211-23.
2002: Alan J Thomas; John T O'Brien; Sue Davis; Clive G Ballard; Robert Barber; Rajesh N. Kalaria; Robert H Perry
Ischemic basis for deep white matter hyperintensities in major depression: a neuropathological study.
Archives of general psychiatry 2002;59(9):785-92.
2002: Alan J Thomas; Ian Nicol Ferrier; Rajesh N. Kalaria; Sue Davis; John T O'Brien
Cell adhesion molecule expression in the dorsolateral prefrontal cortex and anterior cingulate cortex in major depression in the elderly.
The British journal of psychiatry : the journal of mental science 2002;181():129-34.
2002: Clive G Ballard; John T O'Brien; Katharina Reichelt; Elaine K Perry
Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa.
The Journal of clinical psychiatry 2002;63(7):553-8.
2002: Clive G Ballard; Mary Johnson; Margaret A Piggott; Robert H Perry; John T O'Brien; Elise Rowan; Elaine K Perry; Peter Lantos; Nigel J Cairns; Clive Holmes
A positive association between 5HT re-uptake binding sites and depression in dementia with Lewy bodies.
Journal of affective disorders 2002;69(1-3):219-23.
2002: Sean J Colloby; John D Fenwick; E David Williams; Sean M Paling; Kyriakos Lobotesis; Clive G Ballard; Ian G McKeith; John T O'Brien
A comparison of (99m)Tc-HMPAO SPET changes in dementia with Lewy bodies and Alzheimer's disease using statistical parametric mapping.
European journal of nuclear medicine and molecular imaging 2002;29(5):615-22.
2002: Clive G Ballard; John T O'Brien; M Tovee
Qualitative performance characteristics differentiate dementia with Lewy bodies and Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2002;72(5):565-6.
2002: Richard John Porter; Elizabeth F Marshall; John T O'Brien
Effects of rapid tryptophan depletion on salivary and plasma cortisol in Alzheimer's disease and the healthy elderly.
Journal of psychopharmacology (Oxford, England) 2002;16(1):73-8.
2002: Richard John Porter; Nicola A Barnett; Ariane Idey; Elizabeth A McGuckin; John T O'Brien
Effects of hydrocortisone administration on cognitive function in the elderly.
Journal of psychopharmacology (Oxford, England) 2002;16(1):65-71.
2002: Robert Barber; Ian G McKeith; Clive G Ballard; John T O'Brien
Volumetric MRI study of the caudate nucleus in patients with dementia with Lewy bodies, Alzheimer's disease, and vascular dementia.
Journal of neurology, neurosurgery, and psychiatry 2002;72(3):406-7.
2002: Robert C Baldwin; John T O'Brien
Vascular basis of late-onset depressive disorder.
The British journal of psychiatry : the journal of mental science 2002;180():157-60.
2002: Clive G Ballard; Ian Powell; Ian James; Katharina Reichelt; Pat Myint; Dawn Potkins; Carol Bannister; Marisa Lana; Robert Howard; John T O'Brien; Alan Swann; Damian Robinson; Jay Shrimanker; Robert Barber
Can psychiatric liaison reduce neuroleptic use and reduce health service utilization for dementia patients residing in care facilities.
International journal of geriatric psychiatry 2002;17(2):140-5.
2002: Andrew Singleton; Anna Wharton; Kirsty K O'Brien; Matthew P Walker; Ian G McKeith; Clive G Ballard; John T O'Brien; Robert H Perry; Paul Geoffrey Ince; James A Edwardson; Christopher M Morris
Clinical and neuropathological correlates of apolipoprotein E genotype in dementia with Lewy bodies.
Dementia and geriatric cognitive disorders 2002;14(4):167-75.
2002: Michael J Firbank; Roger M Harrison; John T O'Brien
A comprehensive review of proton magnetic resonance spectroscopy studies in dementia and Parkinson's disease.
Dementia and geriatric cognitive disorders 2002;14(2):64-76.
2002: Robert Dudley; John T O'Brien; Nichola Barnett; Liz McGuckin; Peter Britton
Distinguishing depression from dementia in later life: a pilot study employing the Emotional Stroop task.
International journal of geriatric psychiatry 2002;17(1):48-53.
2001: H A M Middelkoop; Wiesje M van der Flier; Emma J Burton; Adrian J Lloyd; Sean M Paling; Robert Barber; Clive G Ballard; Ian G McKeith; John T O'Brien
Dementia with Lewy bodies and AD are not associated with occipital lobe atrophy on MRI.
Neurology 2001;57(11):2117-20.
2001: Jennifer A Court; Clive G Ballard; Margaret A Piggott; Mary Johnson; John T O'Brien; Clive Holmes; Nigel J Cairns; Peter Lantos; Robert H Perry; Evelyn Jaros; Elaine K Perry
Visual hallucinations are associated with lower alpha bungarotoxin binding in dementia with Lewy bodies.
Pharmacology, biochemistry, and behavior 2001;70(4):571-9.
2001: A Luce; Ian G McKeith; Alan Swann; S Daniel; John T O'Brien
How do memory clinics compare with traditional old age psychiatry services?
International journal of geriatric psychiatry 2001;16(9):837-45.
2001: Clive G Ballard; Marisa Margallo-Lana; Jane Fossey; Katharina Reichelt; Pat Myint; Dawn Potkins; John T O'Brien
A 1-year follow-up study of behavioral and psychological symptoms in dementia among people in care environments.
The Journal of clinical psychiatry 2001;62(8):631-6.
2001: John T O'Brien; Clive G Ballard
Drugs for Alzheimer's disease.
BMJ (Clinical research ed.) 2001;323(7305):123-4.
2001: Robert Howard; Clive G Ballard; John T O'Brien; Alistair Burns
Guidelines for the management of agitation in dementia.
International journal of geriatric psychiatry 2001;16(7):714-7.
2001: John T O'Brien; D Ames; Patricia Desmond; M Lichtenstein; David S Binns; Isaac Schweitzer; Sue Davis; Brian M Tress
Combined magnetic resonance imaging and single-photon emission tomography scanning in the discrimination of Alzheimer's disease from age-matched controls.
International psychogeriatrics / IPA 2001;13(2):149-61.
2001: Clive G Ballard; John T O'Brien; Alistair Gray; Francesca Cormack; Gareth Ayre; Elise Rowan; P Thompson; R Bucks; Ian G McKeith; M Walker; M Tovee
Attention and fluctuating attention in patients with dementia with Lewy bodies and Alzheimer disease.
Archives of neurology 2001;58(6):977-82.
2001: John T O'Brien; Sean M Paling; Robert Barber; E David Williams; Clive G Ballard; Ian G McKeith; Anil Gholkar; Bill Crum; Martin N Rossor; Nick C Fox
Progressive brain atrophy on serial MRI in dementia with Lewy bodies, AD, and vascular dementia.
Neurology 2001;56(10):1386-8.
2001: Clive G Ballard; John T O'Brien; C M Morris; Robert Barber; Alan Swann; D Neill; Ian G McKeith
The progression of cognitive impairment in dementia with Lewy bodies, vascular dementia and Alzheimer's disease.
International journal of geriatric psychiatry 2001;16(5):499-503.
2001: Clive G Ballard; M Walker; John T O'Brien; Elise Rowan; Ian G McKeith
The characterisation and impact of 'fluctuating' cognition in dementia with Lewy bodies and Alzheimer's disease.
International journal of geriatric psychiatry 2001;16(5):494-8.
2001: Robert Barber; Ian G McKeith; Clive G Ballard; Anil Gholkar; John T O'Brien
A comparison of medial and lateral temporal lobe atrophy in dementia with Lewy bodies and Alzheimer's disease: magnetic resonance imaging volumetric study.
Dementia and geriatric cognitive disorders 2001;12(3):198-205.
2001: Isaac Schweitzer; Virginia Tuckwell; David Ames; John T O'Brien
Structural neuroimaging studies in late-life depression: a review.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2001;2(2):83-8.
2001: E J Jackson; S Rajah; C Morris; Clive G Ballard; A J Thomas; John T O'Brien
Is apolipoprotein e4 associated with cognitive decline in depression?
International journal of geriatric psychiatry 2001;16(4):436-7.
2001: Marisa Margallo-Lana; Katharina Reichelt; P Hayes; Lesley Lee; Jane Fossey; John T O'Brien; Clive G Ballard
Longitudinal comparison of depression, coping, and turnover among NHS and private sector staff caring for people with dementia.
BMJ (Clinical research ed.) 2001;322(7289):769-70.
2001: K Lobotesis; J D Fenwick; A Phipps; A Ryman; Alan Swann; Clive G Ballard; Ian G McKeith; John T O'Brien
Occipital hypoperfusion on SPECT in dementia with Lewy bodies but not AD.
Neurology 2001;56(5):643-9.
2001: Clive G Ballard; John T O'Brien; I James; P Mynt; Marisa Lana; Dawn Potkins; Katharina Reichelt; L Lee; Alan Swann; Jane Fossey
Quality of life for people with dementia living in residential and nursing home care: the impact of performance on activities of daily living, behavioral and psychological symptoms, language skills, and psychotropic drugs.
International psychogeriatrics / IPA 2001;13(1):93-106.
2001: A J Lloyd; J B Grace; Evelyn Jaros; Robert H Perry; Andrew F Fairbairn; A G Swann; John T O'Brien; Ian G McKeith
Depression in late life, cognitive decline and white matter pathology in two clinico-pathologically investigated cases.
International journal of geriatric psychiatry 2001;16(3):281-7.
2001: John T O'Brien; A Thomas; Clive G Ballard; A Brown; Nicol Ferrier; Evelyn Jaros; Robert H Perry
Cognitive impairment in depression is not associated with neuropathologic evidence of increased vascular or Alzheimer-type pathology.
Biological psychiatry 2001;49(2):130-6.
2001: Rajesh N. Kalaria; Clive G Ballard; Paul Geoffrey Ince; R A Kenny; Ian G McKeith; C M Morris; John T O'Brien; Elaine K Perry; Robert H Perry; J A Edwardson
Multiple substrates of late-onset dementia: implications for brain protection.
Novartis Foundation symposium 2001;235():49-60; discussion 60-5.
2001: Clive G Ballard; John T O'Brien; A G Swann; P Thompson; D Neill; Ian G McKeith
The natural history of psychosis and depression in dementia with Lewy bodies and Alzheimer's disease: persistence and new cases over 1 year of follow-up.
The Journal of clinical psychiatry 2001;62(1):46-9.
2001: Marisa Margallo-Lana; Alan Swann; John T O'Brien; Andrew F Fairbairn; Katharina Reichelt; Dawn Potkins; P Mynt; Clive G Ballard
Prevalence and pharmacological management of behavioural and psychological symptoms amongst dementia sufferers living in care environments.
International journal of geriatric psychiatry 2001;16(1):39-44.
2001: A J Thomas; Ian Nicol Ferrier; Rajesh N. Kalaria; Robert H Perry; A Brown; John T O'Brien
A neuropathological study of vascular factors in late-life depression.
Journal of neurology, neurosurgery, and psychiatry 2001;70(1):83-7.
2000: Clive G Ballard; Margaret A Piggott; Mary Johnson; Nigel J Cairns; Robert H Perry; Ian G McKeith; Evelyn Jaros; John T O'Brien; Clive Holmes; Elaine K Perry
Delusions associated with elevated muscarinic binding in dementia with Lewy bodies.
Annals of neurology 2000;48(6):868-76.
2000: Dawn Potkins; S Bradley; J Shrimanker; John T O'Brien; Alan Swann; Clive G Ballard
End of life treatment decisions in people with dementia: carers' views and the factors which influence them.
International journal of geriatric psychiatry 2000;15(11):1005-8.
2000: Robert Barber; Anil Gholkar; Philip scheltens; Clive G Ballard; Ian G McKeith; John T O'Brien
MRI volumetric correlates of white matter lesions in dementia with Lewy bodies and Alzheimer's disease.
International journal of geriatric psychiatry 2000;15(10):911-6.
2000: Alan J Thomas; Ian Nicol Ferrier; Rajesh N. Kalaria; S A Woodward; Clive G Ballard; A Oakley; Robert H Perry; John T O'Brien
Elevation in late-life depression of intercellular adhesion molecule-1 expression in the dorsolateral prefrontal cortex.
The American journal of psychiatry 2000;157(10):1682-4.
2000: Matthew P Walker; Gareth Ayre; Jeffrey L Cummings; Keith Wesnes; Ian G McKeith; John T O'Brien; Clive G Ballard
The Clinician Assessment of Fluctuation and the One Day Fluctuation Assessment Scale. Two methods to assess fluctuating confusion in dementia.
The British journal of psychiatry : the journal of mental science 2000;177():252-6.
2000: Clive G Ballard; D Neill; John T O'Brien; Ian G McKeith; Paul Ince; Robert H Perry
Anxiety, depression and psychosis in vascular dementia: prevalence and associations.
Journal of affective disorders 2000;59(2):97-106.
2000: Clive G Ballard; John T O'Brien; Alan Swann; D Neill; Peter Lantos; Clive Holmes; David J Burn; Paul Ince; Robert H Perry; Ian G McKeith
One year follow-up of parkinsonism in dementia with Lewy bodies.
Dementia and geriatric cognitive disorders 2000;11(4):219-22.
2000: K Lowery; P Mynt; J Aisbett; T Dixon; John T O'Brien; Clive G Ballard
Depression in the carers of dementia sufferers: a comparison of the carers of patients suffering from dementia with Lewy bodies and the carers of patients with Alzheimer's disease.
Journal of affective disorders 2000;59(1):61-5.
2000: Matthew P Walker; Gareth Ayre; Jeffrey L Cummings; Keith Wesnes; Ian G McKeith; John T O'Brien; Clive G Ballard
Quantifying fluctuation in dementia with Lewy bodies, Alzheimer's disease, and vascular dementia.
Neurology 2000;54(8):1616-25.
2000: John T O'Brien; Robert H Perry; Robert Barber; Anil Gholkar; A Thomas
The association between white matter lesions on magnetic resonance imaging and noncognitive symptoms.
Annals of the New York Academy of Sciences 2000;903():482-9.
2000: Clive G Ballard; John T O'Brien; B Barber; Philip scheltens; F Shaw; Ian G McKeith; R A Kenny
Neurocardiovascular instability, hypotensive episodes, and MRI lesions in neurodegenerative dementia.
Annals of the New York Academy of Sciences 2000;903():442-5.
2000: Richard John Porter; Brian S Lunn; L L Walker; John M Gray; Clive G Ballard; John T O'Brien
Cognitive deficit induced by acute tryptophan depletion in patients with Alzheimer's disease.
The American journal of psychiatry 2000;157(4):638-40.
2000: Robert Barber; Clive G Ballard; Ian G McKeith; Anil Gholkar; John T O'Brien
MRI volumetric study of dementia with Lewy bodies: a comparison with AD and vascular dementia.
Neurology 2000;54(6):1304-9.
2000: Ian G McKeith; Clive G Ballard; Robert H Perry; Paul Geoffrey Ince; John T O'Brien; D Neill; K Lowery; Evelyn Jaros; Robert Barber; P Thompson; Alan Swann; Andrew F Fairbairn; Elaine K Perry
Prospective validation of consensus criteria for the diagnosis of dementia with Lewy bodies.
Neurology 2000;54(5):1050-8.
2000: John T O'Brien; S Metcalfe; A Swann; J Hobson; K Jobst; Clive G Ballard; Ian G McKeith; Anil Gholkar
Medial temporal lobe width on CT scanning in Alzheimer's disease: comparison with vascular dementia, depression and dementia with Lewy bodies.
Dementia and geriatric cognitive disorders 2000;11(2):114-8.
2000: Clive G Ballard; Ian G McKeith; John T O'Brien; Rajesh N. Kalaria; Evelyn Jaros; Paul Ince; Robert H Perry
Neuropathological substrates of dementia and depression in vascular dementia, with a particular focus on cases with small infarct volumes.
Dementia and geriatric cognitive disorders 2000;11(2):59-65.
1999: Ian G McKeith; John T O'Brien
Dementia with Lewy bodies.
The Australian and New Zealand journal of psychiatry 1999;33(6):800-8.
1999: Ian G McKeith; John T O'Brien; Clive G Ballard
Diagnosing dementia with Lewy bodies.
Lancet 1999;354(9186):1227-8.
1999: Timo Erkinjuntti; John V Bowler; Charles DeCarli; Franz Fazekas; Domenico Inzitari; John T O'Brien; Leonardo Pantoni; kenneth rockwood; Philip scheltens; Lars-Olof Wahlund; David W Desmond
Imaging of static brain lesions in vascular dementia: implications for clinical trials.
Alzheimer disease and associated disorders 1999;13 Suppl 3():S81-90.
1999: Robert Barber; Anil Gholkar; Philip scheltens; Clive G Ballard; Ian G McKeith; Christopher M Morris; John T O'Brien
Apolipoprotein E epsilon4 allele, temporal lobe atrophy, and white matter lesions in late-life dementias.
Archives of neurology 1999;56(8):961-5.
1999: Clive G Ballard; John T O'Brien
Treating behavioural and psychological signs in Alzheimer's disease.
BMJ (Clinical research ed.) 1999;319(7203):138-9.
1999: Clive G Ballard; Clive Holmes; Ian G McKeith; D Neill; John T O'Brien; Nigel J Cairns; Peter Lantos; Elaine K Perry; Paul Ince; Robert H Perry
Psychiatric morbidity in dementia with Lewy bodies: a prospective clinical and neuropathological comparative study with Alzheimer's disease.
The American journal of psychiatry 1999;156(7):1039-45.
1999: Robert Barber; Philip scheltens; Anil Gholkar; Clive G Ballard; Ian G McKeith; Paul Ince; Robert H Perry; John T O'Brien
White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer's disease, vascular dementia, and normal aging.
Journal of neurology, neurosurgery, and psychiatry 1999;67(1):66-72.
1999: Robert Barber; Anil Gholkar; Philip scheltens; Clive G Ballard; Ian G McKeith; John T O'Brien
Medial temporal lobe atrophy on MRI in dementia with Lewy bodies.
Neurology 1999;52(6):1153-8.
1999: Clive G Ballard; Gareth Ayre; John T O'Brien; A Sahgal; Ian G McKeith; Paul Geoffrey Ince; Robert H Perry
Simple standardised neuropsychological assessments aid in the differential diagnosis of dementia with Lewy bodies from Alzheimer's disease and vascular dementia.
Dementia and geriatric cognitive disorders 1999;10(2):104-8.
1999: G T Harvey; J Hughes; Ian G McKeith; R Briel; Clive G Ballard; Anil Gholkar; Philip scheltens; Robert H Perry; Paul Ince; John T O'Brien
Magnetic resonance imaging differences between dementia with Lewy bodies and Alzheimer's disease: a pilot study.
Psychological medicine 1999;29(1):181-7.
1998: John T O'Brien; D Ames; E Chiu; Isaac Schweitzer; Patricia Desmond; Brian M Tress
Severe deep white matter lesions and outcome in elderly patients with major depressive disorder: follow up study.
BMJ (Clinical research ed.) 1998;317(7164):982-4.
1998: Clive G Ballard; John T O'Brien; K Lowery; Gareth Ayre; R Harrison; Robert H Perry; Paul Ince; D Neill; Ian G McKeith
A prospective study of dementia with Lewy bodies.
Age and ageing 1998;27(5):631-6.
1998: Richard John Porter; John T O'Brien
SSRIs may well be best treatment for elderly depressed subjects.
BMJ (Clinical research ed.) 1998;316(7131):631.
1997: Clive G Ballard; Ian G McKeith; R Harrison; John T O'Brien; P Thompson; K Lowery; Robert H Perry; Paul Ince
A detailed phenomenological comparison of complex visual hallucinations in dementia with Lewy bodies and Alzheimer's disease.
International psychogeriatrics / IPA 1997;9(4):381-8.
1997: Clive G Ballard; Ian G McKeith; David J Burn; R Harrison; John T O'Brien; K Lowery; M Campbell; Robert H Perry; Paul Ince
The UPDRS scale as a means of identifying extrapyramidal signs in patients suffering from dementia with Lewy bodies.
Acta neurologica Scandinavica 1997;96(6):366-71.
1997: A Swann; John T O'Brien; D Ames; Isaac Schweitzer; Patricia Desmond; Brian M Tress
Does hippocampal atrophy on MRI predict cognitive decline? A prospective follow-up study.
International journal of geriatric psychiatry 1997;12(12):1182-8.
1997: John T O'Brien; Patricia Desmond; D Ames; Isaac Schweitzer; E Chiu; Brian M Tress
Temporal lobe magnetic resonance imaging can differentiate Alzheimer's disease from normal ageing, depression, vascular dementia and other causes of cognitive impairment.
Psychological medicine 1997;27(6):1267-75.
1997: Clive G Ballard; John T O'Brien; B Coope; Gordon K Wilcock
Psychotic symptoms in dementia and the rate of cognitive decline.
Journal of the American Geriatrics Society 1997;45(8):1031-2.
1997: J H Williams; John T O'Brien; S Cullum
Time course of response to electroconvulsive therapy in elderly depressed subjects.
International journal of geriatric psychiatry 1997;12(5):563-6.
1997: Clive G Ballard; John T O'Brien; B Coope; A Fairbairn; F Abid; Gordon K Wilcock
A prospective study of psychotic symptoms in dementia sufferers: psychosis in dementia.
International psychogeriatrics / IPA 1997;9(1):57-64.
1997: John T O'Brien; Patricia Desmond; D Ames; Isaac Schweitzer; Brian M Tress
Magnetic resonance imaging correlates of memory impairment in the healthy elderly: association with medial temporal lobe atrophy but not white matter lesions.
International journal of geriatric psychiatry 1997;12(3):369-74.
1997: John T O'Brien; D Ames; Isaac Schweitzer; Patricia Desmond; P Coleman; Brian M Tress
Clinical, magnetic resonance imaging and endocrinological differences between delusional and non-delusional depression in the elderly.
International journal of geriatric psychiatry 1997;12(2):211-8.
1996: John T O'Brien; C Sale; A Palmer; R Lin; M Kitson
Schizophrenia with poor prognosis associated with hemi-atrophy of the left temporal lobe.
The Journal of nervous and mental disease 1996;184(11):710-1.
1996: John T O'Brien; D Ames
White matter lesions in depression and Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1996;169(5):671.
1996: John T O'Brien; D Ames; Isaac Schweitzer; P Colman; Patricia Desmond; Brian M Tress
Clinical and magnetic resonance imaging correlates of hypothalamic-pituitary-adrenal axis function in depression and Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1996;168(6):679-87.
1996: John T O'Brien; Patricia Desmond; D Ames; Isaac Schweitzer; S Harrigan; Brian M Tress
A magnetic resonance imaging study of white matter lesions in depression and Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1996;168(4):477-85.
1996: M P Page; R J Howard; John T O'Brien; M S Buxton-Thomas; A D Pickering
Use of neural networks in brain SPECT to diagnose Alzheimer's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(2):195-200.
1996: John T O'Brien; D Ames; Isaac Schweitzer; M Mastwyk; P Colman
Enhanced adrenal sensitivity to adrenocorticotrophic hormone (ACTH) is evidence of HPA axis hyperactivity in Alzheimer's disease.
Psychological medicine 1996;26(1):7-14.
1994: John T O'Brien; Isaac Schweitzer; D Ames; M Mastwyk; P Colman
The function of the hypothalamic-pituitary-adrenal axis in Alzheimer's disease. Response to insulin hypoglycaemia.
The British journal of psychiatry : the journal of mental science 1994;165(5):650-7.
1994: Patricia M Desmond; John T O'Brien; Brian M Tress; D J Ames; J G Clement; P Clement; I Schweitzer; Virginia Tuckwell; G S Robinson
Volumetric and visual assessment of the mesial temporal structures in Alzheimer's disease.
Australian and New Zealand journal of medicine 1994;24(5):547-53.
1994: John T O'Brien; Isaac Schweitzer; D Ames; Virginia Tuckwell; M Mastwyk
Cortisol suppression by dexamethasone in the healthy elderly: effects of age, dexamethasone levels, and cognitive function.
Biological psychiatry 1994;36(6):389-94.
1994: John T O'Brien
Cost-effectiveness of antidepressants.
The British journal of psychiatry : the journal of mental science 1994;165(3):411-2.
1994: John T O'Brien; Patricia Desmond; D Ames; Isaac Schweitzer; Virginia Tuckwell; Brian M Tress
The differentiation of depression from dementia by temporal lobe magnetic resonance imaging.
Psychological medicine 1994;24(3):633-40.
1993: John T O'Brien; Barbara J Sahakian; Stuart A Checkley
Cognitive impairments in patients with seasonal affective disorder.
The British journal of psychiatry : the journal of mental science 1993;163():338-43.
1992: John T O'Brien; S Eagger; G M Syed; Barbara J Sahakian; R Levy
A study of regional cerebral blood flow and cognitive performance in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1992;55(12):1182-7.
1992: John T O'Brien; A F Tarbuck
Suicide and vehicle exhaust emissions.
BMJ (Clinical research ed.) 1992;304(6838):1376.
1992: John T O'Brien; R Levy
Age associated memory impairment.
BMJ (Clinical research ed.) 1992;304(6818):5-6.
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