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Paul O'Byrne
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44
Inman, Mark
43
Watson, Richard
38
Gauvreau, Gail
30
Denburg, Judah
24
Hargreave, Frederick
19
Sehmi, Roma
16
Parameswaran, Krishnan
16
Ellis, Russ
13
Cockcroft, Donald
13
Wattie, Jennifer
12
Daniel, Edwin
10
Dorman, Sandra
10
Boulet, Louis-Philippe
9
Duong, Mylinh
9
Jordana, Manel
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All Publications
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2009: O'Byrne Paul M; Gauvreau Gail M; Murphy Desmond M
Efficacy of leukotriene receptor antagonists and synthesis inhibitors in asthma.
The Journal of allergy and clinical immunology 2009;124(3):397-403.
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2009: O'Byrne Paul M; Gauvreau Gail
Phosphodiesterase-4 inhibition in COPD.
Lancet 2009;374(9691):665-7.
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2009: Davis B E; Illamperuma C; Gauvreau G M; Watson R M; O'Byrne P M; Deschesnes F; Boulet L P; Cockcroft D W
Single-dose desloratadine and montelukast and allergen-induced late airway responses.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(6):1302-8.
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2009: Moeller Antje; Gilpin Sarah E; Ask Kjetil; Cox Gerard; Cook Deborah; Gauldie Jack; Margetts Peter J; Farkas Laszlo; Dobranowski Julian; Boylan Colm; O'Byrne Paul M; Strieter Robert M; Kolb Martin
Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis.
American journal of respiratory and critical care medicine 2009;179(7):588-94.
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2009: Nair Parameswaran; Pizzichini Marcia M M; Kjarsgaard Melanie; Inman Mark D; Efthimiadis Ann; Pizzichini Emilio; Hargreave Frederick E; O'Byrne Paul M
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia.
The New England journal of medicine 2009;360(10):985-93.
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2009: O'Byrne P M; Gauvreau G M; Brannan J D
Provoked models of asthma: what have we learnt?
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(2):181-92.
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2009: O'Byrne Paul M; Pedersen Søren; Lamm Carl Johan; Tan Wan C; Busse William W;
Severe exacerbations and decline in lung function in asthma.
American journal of respiratory and critical care medicine 2009;179(1):19-24.
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2008: O'Byrne Paul M; Naya Ian P; Kallen Anders; Postma Dirkje S; Barnes Peter J
Increasing doses of inhaled corticosteroids compared to adding long-acting inhaled beta2-agonists in achieving asthma control.
Chest 2008;134(6):1192-9.
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2008: Jaeschke Roman; O'Byrne Paul M; Nair Parameswaran; Mejza Filip; Lesniak Wiktoria; Brozek Jan; Thabane Lehana; Cheng Ji; Bala Malgorzata; Schünemann Holger J; Sears Malcolm R; Guyatt Gordon
The safety of formoterol among patients with asthma using inhaled corticosteroids. Systematic review and meta-analysis.
Polskie archiwum medycyny wewn?trznej 2008;118(11):627-35.
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2008: Jaeschke Roman; O'Byrne Paul M; Mejza Filip; Nair Parameswaran; Lesniak Wiktoria; Brozek Jan; Thabane Lehana; Cheng Ji; Schünemann Holger J; Sears Malcolm R; Guyatt Gordon
The safety of long-acting beta-agonists among patients with asthma using inhaled corticosteroids: systematic review and metaanalysis.
American journal of respiratory and critical care medicine 2008;178(10):1009-16.
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2008: Kawayama Tomotaka; Kinoshita Takashi; Imaoka Haruki; Gauvreau Gail M; O'Byrne Paul M; Aizawa Hisamichi
Effects of inhaled fluticasone propionate on CTLA-4-positive CD4+CD25+ cells in induced sputum in mild asthmatics.
Respirology (Carlton, Vic.) 2008;13(7):1000-1007.
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2008: Catalli Adriana E; Thomson Jennifer V; Babirad Irene M; Duong Mylinh; Doyle Tracey M; Howie Karen J; Newbold Paul; Craggs Richard I; Foster Martyn; Gauvreau Gail M; O'Byrne Paul M; Sehmi Roma
Modulation of beta1-integrins on hemopoietic progenitor cells after allergen challenge in asthmatic subjects.
The Journal of allergy and clinical immunology 2008;122(4):803-10.
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2008: Pallan Shelley; Mahony James B; O'Byrne Paul M; Nair Parameswaran
Asthma management by monitoring sputum neutrophil count.
Chest 2008;134(3):628-30.
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2008: Duong M; Cockcroft D; Boulet L-P; Ahmed T; Iverson H; Atkinson D C; Stahl E G; Watson R; Davis B; Milot J; Gauvreau G M; O'Byrne P M
The effect of IVX-0142, a heparin-derived hypersulfated disaccharide, on the allergic airway responses in asthma.
Allergy 2008;63(9):1195-201.
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2008: Gauvreau Gail M; Boulet Louis Philippe; Cockcroft Donald W; Baatjes Adrian; Cote Johanne; Deschesnes Francine; Davis Beth; Strinich Tara; Howie Karen; Duong Mylinh; Watson Richard M; Renzi Paolo M; O'Byrne Paul M
Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses.
American journal of respiratory and critical care medicine 2008;177(9):952-8.
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2008: Duong MyLinh; Subbarao Padmaja; Adelroth Ellinor; Obminski George; Strinich Tara; Inman Mark; Pedersen Soren; O'Byrne Paul M
Sputum eosinophils and the response of exercise-induced bronchoconstriction to corticosteroid in asthma.
Chest 2008;133(2):404-11.
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2008: Bateman E D; Hurd S S; Barnes P J; Bousquet J; Drazen J M; FitzGerald M; Gibson P; Ohta K; O'Byrne P; Pedersen S E; Pizzichini E; Sullivan S D; Wenzel S E; Zar H J
Global strategy for asthma management and prevention: GINA executive summary.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;31(1):143-78.
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2008: Llop-Guevara Alba; Colangelo Marc; Chu Derek K; Moore Cheryl Lynn; Stieber Nicole A; Walker Tina D; Goncharova Susanna; Coyle Anthony J; Lundblad Lennart K A; O'Byrne Paul M; Lovric Miroslav; Jordana Manel
In vivo-to-in silico iterations to investigate aeroallergen-host interactions.
PloS one 2008;3(6):e2426.
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2007: Cockcroft Donald W; Hargreave Fredrick E; O'Byrne Paul M; Boulet Louis-Philippe
Understanding allergic asthma from allergen inhalation tests.
Canadian respiratory journal : journal of the Canadian Thoracic Society 2007;14(7):414-8.
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2007: Farrell E; O'Connor T M; Duong M; Watson R M; Strinich T; Gauvreau G M; O'Byrne P M
Circulating myeloid and plasmacytoid dendritic cells after allergen inhalation in asthmatic subjects.
Allergy 2007;62(10):1139-45.
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2007: Xiang Yun-Yan; Wang Shuhe; Liu Mingyao; Hirota Jeremy A; Li Jingxin; Ju William; Fan Yijun; Kelly Margaret M; Ye Bin; Orser Beverley; O'Byrne Paul M; Inman Mark D; Yang Xi; Lu Wei-Yang
A GABAergic system in airway epithelium is essential for mucus overproduction in asthma.
Nature medicine 2007;13(7):862-7.
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2007: O'Byrne Paul M
Acute asthma intervention: insights from the STAY study.
The Journal of allergy and clinical immunology 2007;119(6):1332-6.
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2007: Bousquet J; Clark T J H; Hurd S; Khaltaev N; Lenfant C; O'byrne P; Sheffer A
GINA guidelines on asthma and beyond.
Allergy 2007;62(2):102-12.
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2007: Duong MyLinh; Gauvreau Gail; Watson Richard; Obminski George; Strinich Tara; Evans Michelle; Howie Karen; Killian Kieran; O'Byrne Paul M
The effects of inhaled budesonide and formoterol in combination and alone when given directly after allergen challenge.
The Journal of allergy and clinical immunology 2007;119(2):322-7.
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2007: O'Byrne Paul M
Exacerbations of asthma and COPD: definitions, clinical manifestations and epidemiology.
Contributions to microbiology 2007;14():1-11.
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2006: Kawayama T; O'Byrne P M; Watson R M; Killian K J; Duong M; Yoshida M; Gauvreau G M
Effects of inhaled ciclesonide on circulating T-helper type 1/T-helper type 2 cells in atopic asthmatics after allergen challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(11):1417-24.
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2006: Tan Wan C; Lamm Carl J; Chen Yu-Zhi; O'Byrne Paul M; Pedersen Søren; Busse William W; Ohlsson Stefan V; Ullman Anders; Andersson Bertil; Pauwels Romain A
Effectiveness of early budesonide intervention in Caucasian versus Asian patients with asthma: 3-year results of the START study.
Respirology (Carlton, Vic.) 2006;11(6):767-75.
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2006: Kelly Margaret M; Chakir Jamila; Vethanayagam Dilini; Boulet Louis-Philippe; Laviolette Michel; Gauldie Jack; O'Byrne Paul M
Montelukast treatment attenuates the increase in myofibroblasts following low-dose allergen challenge.
Chest 2006;130(3):741-53.
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2006: O'Byrne Paul M; Parameswaran Krishnan
Pharmacological management of mild or moderate persistent asthma.
Lancet 2006;368(9537):794-803.
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2006: O'Byrne Paul M
Cytokines or their antagonists for the treatment of asthma.
Chest 2006;130(1):244-50.
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2006: Gauvreau Gail M; Hessel Edith M; Boulet Louis-Philippe; Coffman Robert L; O'Byrne Paul M
Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses.
American journal of respiratory and critical care medicine 2006;174(1):15-20.
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2006: O'Byrne Paul M; Pedersen Søren; Busse William W; Tan Wan C; Chen Yu-Zhi; Ohlsson Stefan V; Ullman Anders; Lamm Carl Johan; Pauwels Romain A
Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma.
Chest 2006;129(6):1478-85.
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2006: Parameswaran K; Fanat A; O'Byrne P M
Effects of intranasal fluticasone and salmeterol on allergen-induced nasal responses.
Allergy 2006;61(6):731-6.
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2006: Subbarao Padmaja; Duong Mylinh; Adelroth Ellinor; Otis Joceline; Obminski George; Inman Mark; Pedersen Soren; O'byrne Paul M
Effect of ciclesonide dose and duration of therapy on exercise-induced bronchoconstriction in patients with asthma.
The Journal of allergy and clinical immunology 2006;117(5):1008-13.
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2006: Belda Jose; Parameswaran Krishnan; Lemière Catherine; Kamada Dennis; O'Byrne Paul M; Hargreave Frederick E
Predictors of loss of asthma control induced by corticosteroid withdrawal.
Canadian respiratory journal : journal of the Canadian Thoracic Society 2006;13(3):129-33.
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2006: O'Byrne Paul M; Adelroth Ellinor
Beta2 déjà vu.
Chest 2006;129(1):3-5.
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2005: Gauvreau Gail M; Boulet Louis Philippe; Postma Dirkje S; Kawayama Tomotaka; Watson Richard M; Duong MyLinh; Deschesnes Francine; De Monchy Jan G R; O'Byrne Paul M
Effect of low-dose ciclesonide on allergen-induced responses in subjects with mild allergic asthma.
The Journal of allergy and clinical immunology 2005;116(2):285-91.
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2005: O'Byrne Paul M
Initiation, dose reduction, and duration of inhaled corticosteroid therapy.
Immunology and allergy clinics of North America 2005;25(3):511-21, vi.
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2005: Yoshida Makoto; Watson Richard M; Rerecich Tracy; O'Byrne Paul M
Different profiles of T-cell IFN-gamma and IL-12 in allergen-induced early and dual responders with asthma.
The Journal of allergy and clinical immunology 2005;115(5):1004-9.
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2005: Subbarao Padmaja; Dorman Sandra C; Rerecich Tracey; Watson Richard M; Gauvreau Gail M; O'Byrne Paul M
Protection by budesonide and fluticasone on allergen-induced airway responses after discontinuation of therapy.
The Journal of allergy and clinical immunology 2005;115(4):745-50.
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2005: Dorman Sandra C; Babirad Irene; Post Julia; Watson Rick M; Foley Ronan; Jones Graham L; O'Byrne Paul M; Sehmi Roma
Progenitor egress from the bone marrow after allergen challenge: role of stromal cell-derived factor 1alpha and eotaxin.
The Journal of allergy and clinical immunology 2005;115(3):501-7.
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2005: Cockcroft D W; Davis B E; Boulet L-P; Deschesnes F; Gauvreau G M; O'Byrne P M; Watson R M
The links between allergen skin test sensitivity, airway responsiveness and airway response to allergen.
Allergy 2005;60(1):56-9.
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2005: O'Byrne Paul M; Bisgaard Hans; Godard Philippe P; Pistolesi Massimo; Palmqvist Mona; Zhu Yuanjue; Ekström Tommy; Bateman Eric D
Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma.
American journal of respiratory and critical care medicine 2005;171(2):129-36.
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2004: Parameswaran K; Radford K; Zuo J; Janssen L J; O'Byrne P M; Cox P G
Extracellular matrix regulates human airway smooth muscle cell migration.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(4):545-51.
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2004: Parameswaran Krishnan; Liang Hong; Fanat Adrian; Watson Richard; Snider Denis P; O'Byrne Paul M
Role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in asthma.
The Journal of allergy and clinical immunology 2004;114(1):73-9.
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2004: O'Byrne Paul M; Inman Mark D; Adelroth Ellinor
Reassessing the Th2 cytokine basis of asthma.
Trends in pharmacological sciences 2004;25(5):244-8.
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2004: Parameswaran Krishnan; Watson Richard; Gauvreau Gail M; Sehmi Roma; O'Byrne Paul M
The effect of pranlukast on allergen-induced bone marrow eosinophilopoiesis in subjects with asthma.
American journal of respiratory and critical care medicine 2004;169(8):915-20.
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2004: Leigh Richard; Ellis Russ; Wattie Jennifer N; Hirota Jeremy A; Matthaei Klaus I; Foster Paul S; O'Byrne Paul M; Inman Mark D
Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice.
American journal of respiratory and critical care medicine 2004;169(7):860-7.
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2004: Wilson Andrew M; O'Byrne Paul M; Parameswaran Krishnan
Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis.
The American journal of medicine 2004;116(5):338-44.
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2004: Dorman Sandra C; Sehmi Roma; Gauvreau Gail M; Watson Rick M; Foley Ronan; Jones Graham L; Denburg Judah A; Inman Mark D; O'Byrne Paul M
Kinetics of bone marrow eosinophilopoiesis and associated cytokines after allergen inhalation.
American journal of respiratory and critical care medicine 2004;169(5):565-72.
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2004: Dorman Sandra C; Efthimiadis Ann; Babirad Irene; Watson Rick M; Denburg Judah A; Hargreave Frederick E; O'Byrne Paul M; Sehmi Roma
Sputum CD34+IL-5Ralpha+ cells increase after allergen: evidence for in situ eosinophilopoiesis.
American journal of respiratory and critical care medicine 2004;169(5):573-7.
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2004: Juniper E F; Wisniewski M E; Cox F M; Emmett A H; Nielsen K E; O'Byrne P M
Relationship between quality of life and clinical status in asthma: a factor analysis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;23(2):287-91.
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2004: Matsumoto K; Narita S; Rerecich T; Snider D P; O'Byrne P M
Different profile of interleukin-10 production in circulating T cells from atopic asthmatics compared with healthy subjects.
Canadian respiratory journal : journal of the Canadian Thoracic Society 2004;11(1):33-8.
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2004: O'Byrne Paul M
Pharmacologic interventions to reduce the risk of asthma exacerbations.
Proceedings of the American Thoracic Society 2004;1(2):105-8.
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2003: Ellis Russ; Leigh Richard; Southam David; O'Byrne Paul M; Inman Mark D
Morphometric analysis of mouse airways after chronic allergen challenge.
Laboratory investigation; a journal of technical methods and pathology 2003;83(9):1285-91.
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2003: Gauvreau Gail M; Becker Allan B; Boulet Louis-Philippe; Chakir Jamila; Fick Robert B; Greene William L; Killian Kieran J; O'byrne Paul M; Reid John K; Cockcroft Donald W
The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma.
The Journal of allergy and clinical immunology 2003;112(2):331-8.
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2003: Sehmi Roma; Dorman Sandra; Baatjes Adrian; Watson Rick; Foley Ronan; Ying Sun; Robinson Douglas S; Kay A Barry; O'Byrne Paul M; Denburg Judah A
Allergen-induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of haemopoietic progenitor cells in allergic inflammation.
Immunology 2003;109(4):536-46.
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2003: Parameswaran Krishnan; O'Byrne Paul M; Sears Malcolm R
Inhaled corticosteroids for asthma: common clinical quandaries.
The Journal of asthma : official journal of the Association for the Care of Asthma 2003;40(2):107-18.
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2003: Pauwels Romain A; Pedersen Søren; Busse William W; Tan Wan C; Chen Yu-Zhi; Ohlsson Stefan V; Ullman Anders; Lamm Carl Johan; O'Byrne Paul M;
Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial.
Lancet 2003;361(9363):1071-6.
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2003: O'Byrne Paul M; Inman Mark D
Airway hyperresponsiveness.
Chest 2003;123(3 Suppl):411S-6S.
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2003: Parameswaran Krishnan; Leigh Richard; O'Byrne Paul M; Kelly Margaret M; Goldsmith Charlie H; Hargreave Frederick E; Dolovich Myrna
Clinical models to compare the safety and efficacy of inhaled corticosteroids in patients with asthma.
Canadian respiratory journal : journal of the Canadian Thoracic Society 2003;10(1):27-34.
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2002: Leigh Richard; Vethanayagam Dilini; Yoshida Makoto; Watson Richard M; Rerecich Tracy; Inman Mark D; O'Byrne Paul M
Effects of montelukast and budesonide on airway responses and airway inflammation in asthma.
American journal of respiratory and critical care medicine 2002;166(9):1212-7.
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2002: Leigh Richard; Ellis Russ; Wattie Jennifer; Southam David S; De Hoogh Meta; Gauldie Jack; O'Byrne Paul M; Inman Mark D
Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation.
American journal of respiratory cell and molecular biology 2002;27(5):526-35.
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2002: Wood Lorna J; Sehmi Roma; Dorman Sandra; Hamid Qutayba; Tulic Meri K; Watson Richard M; Foley Ronan; Wasi Parveen; Denburg Judah A; Gauvreau Gail; O'Byrne Paul M
Allergen-induced increases in bone marrow T lymphocytes and interleukin-5 expression in subjects with asthma.
American journal of respiratory and critical care medicine 2002;166(6):883-9.
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2002: Parameswaran Krishnan; Cox Gerard; Radford Katherine; Janssen Luke J; Sehmi Roma; O'Byrne Paul M
Cysteinyl leukotrienes promote human airway smooth muscle migration.
American journal of respiratory and critical care medicine 2002;166(5):738-42.
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2002: Yoshida Makoto; Leigh Richard; Matsumoto Koichiro; Wattie Jennifer; Ellis Russ; O'Byrne Paul M; Inman Mark D
Effect of interferon-gamma on allergic airway responses in interferon-gamma-deficient mice.
American journal of respiratory and critical care medicine 2002;166(4):451-6.
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2002: Baatjes Adrian J; Sehmi Roma; Saito Hiroko; Cyr Michael M; Dorman Sandra C; Inman Mark D; O'Byrne Paul M; Denburg Judah A
Anti-allergic therapies: effects on eosinophil progenitors.
Pharmacology & therapeutics 2002;95(1):63-72.
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2002: Shen Huahao; O'Byrne Paul M; Ellis Russ; Wattie Jennifer; Tang Chibing; Inman Mark D
The effects of intranasal budesonide on allergen-induced production of interleukin-5 and eotaxin, airways, blood, and bone marrow eosinophilia, and eosinophil progenitor expansion in sensitized mice.
American journal of respiratory and critical care medicine 2002;166(2):146-53.
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2002: Braccioni Fausto; Dorman Sandra C; O'byrne Paul M; Inman Mark D; Denburg Judah A; Parameswaran Krishnan; Baatjes Adrian J; Foley Ronan; Gauvreau Gail M
The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects.
The Journal of allergy and clinical immunology 2002;110(1):96-101.
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2002: Upham J W; Denburg J A; O'Byrne P M
Rapid response of circulating myeloid dendritic cells to inhaled allergen in asthmatic subjects.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(6):818-23.
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2002: Dahlén Barbro; Roquet Annika; Inman Mark D; Karlsson Osten; Naya Ian; Anstrén Gudrun; O'Byrne Paul M; Dahlén Sven-Erik
Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction.
The Journal of allergy and clinical immunology 2002;109(5):789-93.
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2002: Southam D S; Dolovich M; O'Byrne P M; Inman M D
Distribution of intranasal instillations in mice: effects of volume, time, body position, and anesthesia.
American journal of physiology. Lung cellular and molecular physiology 2002;282(4):L833-9.
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2002: Matsumoto Koichiro; Gauvreau Gail M; Rerecich Tracy; Watson Richard M; Wood Lorna J; O'Byrne Paul M
IL-10 production in circulating T cells differs between allergen-induced isolated early and dual asthmatic responders.
The Journal of allergy and clinical immunology 2002;109(2):281-6.
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2002: Parameswaran Krishnan; Janssen Luke J; O'Byrne Paul M
Airway hyperresponsiveness and calcium handling by smooth muscle: a "deeper look".
Chest 2002;121(2):621-4.
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2002: Gauvreau Gail M; Inman Mark D; Kelly Margaret; Watson Richard M; Dorman Sandra C; O'Byrne Paul M
Increased levels of airway neutrophils reduce the inhibitory effects of inhaled glucocorticosteroids on allergen-induced airway eosinophils.
Canadian respiratory journal : journal of the Canadian Thoracic Society 2002;9(1):26-32.
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2001: O'Byrne P M; Barnes P J; Rodriguez-Roisin R; Runnerstrom E; Sandstrom T; Svensson K; Tattersfield A
Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial.
American journal of respiratory and critical care medicine 2001;164(8 Pt 1):1392-7.
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2001: O'Byrne P M; Inman M D; Parameswaran K
The trials and tribulations of IL-5, eosinophils, and allergic asthma.
The Journal of allergy and clinical immunology 2001;108(4):503-8.
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2001: Inman M D; Watson R M; Rerecich T; Gauvreau G M; Lutsky B N; Stryszak P; O'Byrne P M
Dose-dependent effects of inhaled mometasone furoate on airway function and inflammation after allergen inhalation challenge.
American journal of respiratory and critical care medicine 2001;164(4):569-74.
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2001: Sullivan S D; Liljas B; Buxton M; Lamm C J; O'Byrne P; Tan W C; Weiss K B;
Design and analytic considerations in determining the cost-effectiveness of early intervention in asthma from a multinational clinical trial.
Controlled clinical trials 2001;22(4):420-37.
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2001: Pauwels R A; Busse W W; O'Byrne P M; Pedersen S; Tan W C; Chen Y Z; Ohlsson S V; Ullman A
The inhaled Steroid Treatment as Regular Therapy in early asthma (START) study: rationale and design.
Controlled clinical trials 2001;22(4):405-19.
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2001: Andersson F; Stahl E; Barnes P J; Löfdahl C G; O'Byrne P M; Pauwels R A; Postma D S; Tattersfield A E; Ullman A;
Adding formoterol to budesonide in moderate asthma--health economic results from the FACET study.
Respiratory medicine 2001;95(6):505-12.
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2001: Juniper E F; O'Byrne P M; Roberts J N
Measuring asthma control in group studies: do we need airway calibre and rescue beta2-agonist use?
Respiratory medicine 2001;95(5):319-23.
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2001: Dahlén B; O'Byrne P M; Watson R M; Roquet A; Larsen F; Inman M D
The reproducibility and sample size requirements of exercise-induced bronchoconstriction measurements.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;17(4):581-8.
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2001: Tang C; Inman M D; van Rooijen N; Yang P; Shen H; Matsumoto K; O'Byrne P M
Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-gamma-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1471-81.
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2000: Gauvreau G M; Wood L J; Sehmi R; Watson R M; Dorman S C; Schleimer R P; Denburg J A; O'Byrne P M
The effects of inhaled budesonide on circulating eosinophil progenitors and their expression of cytokines after allergen challenge in subjects with atopic asthma.
American journal of respiratory and critical care medicine 2000;162(6):2139-44.
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2000: Denburg J A; Sehmi R; Saito H; Pil-Seob J; Inman M D; O'Byrne P M
Systemic aspects of allergic disease: bone marrow responses.
The Journal of allergy and clinical immunology 2000;106(5 Suppl):S242-6.
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2000: Juniper E F; O'Byrne P M; Ferrie P J; King D R; Roberts J N
Measuring asthma control. Clinic questionnaire or daily diary?
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1330-4.
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2000: Gauvreau G M; Ronnen G M; Watson R M; O'Byrne P M
Exercise-induced bronchoconstriction does not cause eosinophilic airway inflammation or airway hyperresponsiveness in subjects with asthma.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1302-7.
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2000: Gauvreau G M; Sulakvelidze I; Watson R M; Inman M D; Rerecich T J; O'Byrne P M
Effects of once daily dosing with inhaled budesonide on airway hyperresponsiveness and airway inflammation following repeated low-dose allergen challenge in atopic asthmatics.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(9):1235-43.
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2000: Killian K J; Watson R; Otis J; St Amand T A; O'Byrne P M
Symptom perception during acute bronchoconstriction.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):490-6.
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2000: Parameswaran K; Inman M D; Watson R M; Morris M M; Efthimiadis A; Ventresca P G; Lam R; O'Byrne P M; Hargreave F E
Protective effects of fluticasone on allergen-induced airway responses and sputum inflammatory markers.
Canadian respiratory journal : journal of the Canadian Thoracic Society 2000;7(4):313-9.
-
2000: O'Byrne P M; Inman M D
New considerations about measuring airway hyperresponsiveness.
The Journal of asthma : official journal of the Association for the Care of Asthma 2000;37(4):293-302.
-
2000: Gauvreau G M; Lee J M; Watson R M; Irani A M; Schwartz L B; O'Byrne P M
Increased numbers of both airway basophils and mast cells in sputum after allergen inhalation challenge of atopic asthmatics.
American journal of respiratory and critical care medicine 2000;161(5):1473-8.
-
2000: Upham J W; Lundahl J; Liang H; Denburg J A; O'Byrne P M; Snider D P
Simplified quantitation of myeloid dendritic cells in peripheral blood using flow cytometry.
Cytometry 2000;40(1):50-9.
-
2000: Janssen L J; Djuric V J; Wattie J; Otis J; O'Byrne P M
In vitro airway responsiveness of Flinders sensitive and resistant line rats.
Brain, behavior, and immunity 2000;14(1):62-7.
-
2000: O'Byrne P M
Why does airway inflammation persist? Is it leukotrienes?
American journal of respiratory and critical care medicine 2000;161(3 Pt 2):S186-7.
-
2000: Kips J C; O'Connor B J; Inman M D; Svensson K; Pauwels R A; O'Byrne P M
A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma.
American journal of respiratory and critical care medicine 2000;161(3 Pt 1):996-1001.
-
2000: O'Byrne P M
Leukotriene bronchoconstriction induced by allergen and exercise.
American journal of respiratory and critical care medicine 2000;161(2 Pt 2):S68-72.
-
2000: Belda J; Leigh R; Parameswaran K; O'Byrne P M; Sears M R; Hargreave F E
Induced sputum cell counts in healthy adults.
American journal of respiratory and critical care medicine 2000;161(2 Pt 1):475-8.
-
1999: Juniper E F; Svensson K; O'Byrne P M; Barnes P J; Bauer C A; Löfdahl C G; Postma D S; Pauwels R A; Tattersfield A E; Ullman A
Asthma quality of life during 1 year of treatment with budesonide with or without formoterol.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(5):1038-43.
-
1999: Juniper E F; O'Byrne P M; Guyatt G H; Ferrie P J; King D R
Development and validation of a questionnaire to measure asthma control.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(4):902-7.
-
1999: Inman M D; Ellis R; Wattie J; Denburg J A; O'Byrne P M
Allergen-induced increase in airway responsiveness, airway eosinophilia, and bone-marrow eosinophil progenitors in mice.
American journal of respiratory cell and molecular biology 1999;21(4):473-9.
-
1999: Gauvreau G M; Watson R M; O'Byrne P M
Kinetics of allergen-induced airway eosinophilic cytokine production and airway inflammation.
American journal of respiratory and critical care medicine 1999;160(2):640-7.
-
1999: Tattersfield A E; Postma D S; Barnes P J; Svensson K; Bauer C A; O'Byrne P M; Löfdahl C G; Pauwels R A; Ullman A
Exacerbations of asthma: a descriptive study of 425 severe exacerbations. The FACET International Study Group.
American journal of respiratory and critical care medicine 1999;160(2):594-9.
-
1999: Gauvreau G M; Watson R M; Rerecich T J; Baswick E; Inman M D; O'Byrne P M
Repeatability of allergen-induced airway inflammation.
The Journal of allergy and clinical immunology 1999;104(1):66-71.
-
1999: Parameswaran K N; Inman M D; Ekholm B P; Morris M M; Summers E; O'Byrne P M; Hargreave F E
Protection against methacholine bronchoconstriction to assess relative potency of inhaled beta2-agonist.
American journal of respiratory and critical care medicine 1999;160(1):354-7.
-
1999: O'Byrne P M; Gauvreau G M; Wood L J
Interaction between haemopoietic regulation and airway inflammation.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29 Suppl 2():27-32.
-
1999: O'byrne P M; Postma D S
The many faces of airway inflammation. Asthma and chronic obstructive pulmonary disease. Asthma Research Group.
American journal of respiratory and critical care medicine 1999;159(5 Pt 2):S41-63.
-
1999: Mulder A; Gauvreau G M; Watson R M; O'byrne P M
Effect of inhaled leukotriene D4 on airway eosinophilia and airway hyperresponsiveness in asthmatic subjects.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1562-7.
-
1999: Wood L J; Sehmi R; Gauvreau G M; Watson R M; Foley R; Denburg J A; O'byrne P M
An inhaled corticosteroid, budesonide, reduces baseline but not allergen-induced increases in bone marrow inflammatory cell progenitors in asthmatic subjects.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1457-63.
-
1999: Denburg J A; Sehmi R; Upham J; Wood L; Gauvreau G; O'Byrne P
Regulation of IL-5 and IL-5 receptor expression in the bone marrow of allergic asthmatics.
International archives of allergy and immunology 1999;118(2-4):101-3.
-
1999: O'Byrne P M; Inman M D
The clinical expression of allergy in the lungs.
Allergy 1999;54(1):7-14.
-
1999: Gauvreau G M; Watson R M; O'Byrne P M
Protective effects of inhaled PGE2 on allergen-induced airway responses and airway inflammation.
American journal of respiratory and critical care medicine 1999;159(1):31-6.
-
1998: Denburg J A; Inman M D; Sehmi R; Uno M; O'Byrne P M
Hemopoietic mechanisms in allergic airway inflammation.
International archives of allergy and immunology 1998;117(3):155-9.
-
1998: O'Byrne P
Asthma pathogenesis and allergen-induced late responses.
The Journal of allergy and clinical immunology 1998;102(5):S85-9.
-
1998: O'Sullivan S; Roquet A; Dahlén B; Larsen F; Eklund A; Kumlin M; O'Byrne P M; Dahlén S E
Evidence for mast cell activation during exercise-induced bronchoconstriction.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(2):345-50.
-
1998: Hamilton A; Faiferman I; Stober P; Watson R M; O'Byrne P M
Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects.
The Journal of allergy and clinical immunology 1998;102(2):177-83.
-
1998: O'Byrne P M
Asthma treatment: antileukotriene drugs.
Canadian respiratory journal : journal of the Canadian Thoracic Society 1998;5 Suppl A():64A-70A.
-
1998: Gauvreau G M; O'Byrne P M; Moqbel R; Velazquez J; Watson R M; Howie K J; Denburg J A
Enhanced expression of GM-CSF in differentiating eosinophils of atopic and atopic asthmatic subjects.
American journal of respiratory cell and molecular biology 1998;19(1):55-62.
-
1998: Wood L J; Inman M D; Denburg J A; O'Byrne P M
Allergen challenge increases cell traffic between bone marrow and lung.
American journal of respiratory cell and molecular biology 1998;18(6):759-67.
-
1998: Lötvall J; Inman M; O'Byrne P
Measurement of airway hyperresponsiveness: new considerations.
Thorax 1998;53(5):419-24.
-
1998: Pizzichini E; Pizzichini M M; Kidney J C; Efthimiadis A; Hussack P; Popov T; Cox G; Dolovich J; O'Byrne P; Hargreave F E
Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: inflammatory cells, lymphocyte subsets and soluble markers compared.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;11(4):828-34.
-
1998: Sulakvelidze I; Inman M D; Rerecich T; O'Byrne P M
Increases in airway eosinophils and interleukin-5 with minimal bronchoconstriction during repeated low-dose allergen challenge in atopic asthmatics.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;11(4):821-7.
-
1998: Wong A G; O'Byrne P M; Lindbladh C; Inman M D; Stâhl E; Hargreave F E
Dose-response protective effect of salbutamol on methacholine airway responsiveness using pressurized metered dose inhalers and Turbuhalers.
Canadian respiratory journal : journal of the Canadian Thoracic Society 1998;5(2):119-23.
-
1998: Inman M D; Hamilton A L; Kerstjens H A; Watson R M; O'Byrne P M
The utility of methacholine airway responsiveness measurements in evaluating anti-asthma drugs.
The Journal of allergy and clinical immunology 1998;101(3):342-8.
-
1998: McGrogan I; Janssen L J; Wattie J; O'Byrne P M; Daniel E E
Release of epithelium-derived PGE2 from canine trachea after antigen inhalation.
The American journal of physiology 1998;274(2 Pt 1):L220-5.
-
1998: Wood L J; Inman M D; Watson R M; Foley R; Denburg J A; O'Byrne P M
Changes in bone marrow inflammatory cell progenitors after inhaled allergen in asthmatic subjects.
American journal of respiratory and critical care medicine 1998;157(1):99-105.
-
1998: O'Byrne P M; Gauvreau G M; Wood L J
Pharmacologic modulation of airway inflammation.
Allergy 1998;53(45 Suppl):41-7.
-
1997: Janssen L J; McGrogan I; Wattie J; O'Byrne P M; Daniel E E
Myogenic and neurogenic mechanisms and arachidonate metabolites in bronchial muscle response to allergen.
The American journal of physiology 1997;273(6 Pt 1):L1118-25.
-
1997: Gauvreau G M; Jordana M; Watson R M; Cockroft D W; O'Byrne P M
Effect of regular inhaled albuterol on allergen-induced late responses and sputum eosinophils in asthmatic subjects.
American journal of respiratory and critical care medicine 1997;156(6):1738-45.
-
1997: Inman M D; Denburg J A; Ellis R; Dahlbäck M; O'Byrne P M
The effect of treatment with budesonide or PGE2 in vitro on allergen-induced increases in canine bone marrow progenitors.
American journal of respiratory cell and molecular biology 1997;17(5):634-41.
-
1997: Sehmi R; Wood L J; Watson R; Foley R; Hamid Q; O'Byrne P M; Denburg J A
Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation.
The Journal of clinical investigation 1997;100(10):2466-75.
-
1997: Pauwels R A; Löfdahl C G; Postma D S; Tattersfield A E; O'Byrne P; Barnes P J; Ullman A
Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group.
The New England journal of medicine 1997;337(20):1405-11.
-
1997: O'Byrne P M; Israel E; Drazen J M
Antileukotrienes in the treatment of asthma.
Annals of internal medicine 1997;127(6):472-80.
-
1997: Kidney J C; Boulet L P; Hargreave F E; Deschesnes F; Swystun V A; O'Byrne P M; Choudry N; Morris M M; Jennings B; Andersson N; Andreasson A; Cockcroft D W
Evaluation of single-dose inhaled corticosteroid activity with an allergen challenge model.
The Journal of allergy and clinical immunology 1997;100(1):65-70.
-
1997: Gizycki M J; Adelroth E; Rogers A V; O'Byrne P M; Jeffery P K
Myofibroblast involvement in the allergen-induced late response in mild atopic asthma.
American journal of respiratory cell and molecular biology 1997;16(6):664-73.
-
1997: Denburg J A; Inman M D; Wood L; Ellis R; Sehmi R; Dahlback M; O'Byrne P
Bone marrow progenitors in allergic airways diseases: studies in canine and human models.
International archives of allergy and immunology 1997;113(1-3):181-3.
-
1997: Hamilton A L; Watson R M; Wyile G; O'Byrne P M
Attenuation of early and late phase allergen-induced bronchoconstriction in asthmatic subjects by a 5-lipoxygenase activating protein antagonist, BAYx 1005.
Thorax 1997;52(4):348-54.
-
1997: O'Byrne P M
Treatment of mild asthma.
Lancet 1997;349(9055):818.
-
1997: Adelroth E; Inman M D; Summers E; Pace D; Modi M; O'Byrne P M
Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4-receptor antagonist cinalukast.
The Journal of allergy and clinical immunology 1997;99(2):210-5.
-
1997: O'Byrne P M
Leukotrienes in the pathogenesis of asthma.
Chest 1997;111(2 Suppl):27S-34S.
-
1997: O'Byrne P M
Exercise-induced bronchoconstriction: elucidating the roles of leukotrienes and prostaglandins.
Pharmacotherapy 1997;17(1 Pt 2):31S-38S.
-
1997: Denburg J A; Wood L; Gauvreau G; Sehmi R; Inman M D; O'Byrne P M
Bone marrow contribution to eosinophilic inflammation.
Memórias do Instituto Oswaldo Cruz 1997;92 Suppl 2():33-5.
-
1996: Sehmi R; Howie K; Sutherland D R; Schragge W; O'Byrne P M; Denburg J A
Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects.
American journal of respiratory cell and molecular biology 1996;15(5):645-55.
-
1996: Gauvreau G M; Doctor J; Watson R M; Jordana M; O'Byrne P M
Effects of inhaled budesonide on allergen-induced airway responses and airway inflammation.
American journal of respiratory and critical care medicine 1996;154(5):1267-71.
-
1996: Inman M D; Denburg J A; Ellis R; Dahlback M; O'Byrne P M
Allergen-induced increase in bone marrow progenitors in airway hyperresponsive dogs: regulation by a serum hemopoietic factor.
American journal of respiratory cell and molecular biology 1996;15(3):305-11.
-
1996: Ohno I; Nitta Y; Yamauchi K; Hoshi H; Honma M; Woolley K; O'Byrne P; Tamura G; Jordana M; Shirato K
Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation.
American journal of respiratory cell and molecular biology 1996;15(3):404-9.
-
1996: Denburg J A; Inman M D; Leber B; Sehmi R; O'Byrne P M
The role of the bone marrow in allergy and asthma.
Allergy 1996;51(3):141-8.
-
1996: Inman M D; O'Byrne P M
The effect of regular inhaled albuterol on exercise-induced bronchoconstriction.
American journal of respiratory and critical care medicine 1996;153(1):65-9.
-
1996: Woolley K L; Adelroth E; Woolley M J; Ramis I; Abrams J S; Jordana M; O'Byrne P M
Interleukin-3 in bronchial biopsies from nonasthmatics and patients with mild and allergen-induced asthma.
American journal of respiratory and critical care medicine 1996;153(1):350-5.
-
1996: O'Byrne P M
Airway inflammation and asthma.
Alimentary pharmacology & therapeutics 1996;10 Suppl 2():18-24.
-
1995: Ohno I; Nitta Y; Yamauchi K; Hoshi H; Honma M; Woolley K; O'Byrne P; Dolovich J; Jordana M; Tamura G
Eosinophils as a potential source of platelet-derived growth factor B-chain (PDGF-B) in nasal polyposis and bronchial asthma.
American journal of respiratory cell and molecular biology 1995;13(6):639-47.
-
1995: Woolley M J; Lane C G; Ellis R; Stevens W H; Woolley K L; O'Byrne P M
Role of airway eosinophils in the development of allergen-induced airway hyperresponsiveness in dogs.
American journal of respiratory and critical care medicine 1995;152(5 Pt 1):1508-12.
-
1995: Stevens W H; Vanderheyden C; Wattie J; Lane C G; Smith W; O'Byrne P M
Effect of a leukotriene B4 receptor antagonist SC-53228 on ozone-induced airway hyperresponsiveness and inflammation in dogs.
American journal of respiratory and critical care medicine 1995;152(5 Pt 1):1443-8.
-
1995: Stevens W H; Adelroth E; Woolley M J; Wattie J; Dahlbäck M; O'Byrne P M
The effects of an inhaled corticosteroid on oxygen radical production by bronchoalveolar cells after allergen or ozone in dogs.
European journal of pharmacology 1995;293(3):251-7.
-
1995: Nonaka M; Nonaka R; Woolley K; Adelroth E; Miura K; Okhawara Y; Glibetic M; Nakano K; O'Byrne P; Dolovich J
Distinct immunohistochemical localization of IL-4 in human inflamed airway tissues. IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(6):3234-44.
-
1995: Cockcroft D W; O'Byrne P M; Swystun V A; Bhagat R
Regular use of inhaled albuterol and the allergen-induced late asthmatic response.
The Journal of allergy and clinical immunology 1995;96(1):44-9.
-
1995: Stevens W H; Conlon P D; O'Byrne P M
Ozone-induced oxygen radical release from bronchoalveolar lavage cells and airway hyper-responsiveness in dogs.
The Journal of physiology 1995;486 ( Pt 1)():257-65.
-
1995: Inman M D; Watson R; Cockcroft D W; Wong B J; Hargreave F E; O'Byrne P M
Reproducibility of allergen-induced early and late asthmatic responses.
The Journal of allergy and clinical immunology 1995;95(6):1191-5.
-
1995: Woolley K L; Adelroth E; Woolley M J; Ellis R; Jordana M; O'Byrne P M
Effects of allergen challenge on eosinophils, eosinophil cationic protein, and granulocyte-macrophage colony-stimulating factor in mild asthma.
American journal of respiratory and critical care medicine 1995;151(6):1915-24.
-
1995: Stevens W H; Inman M D; Wattie J; O'Byrne P M
Allergen-induced oxygen radical release from bronchoalveolar lavage cells and airway hyperresponsiveness in dogs.
American journal of respiratory and critical care medicine 1995;151(5):1526-31.
-
1995: Denburg J A; Woolley M J; Ellis R; Dahlback M; O'Byrne P M
Allergen-induced changes in bone marrow progenitors and airway responsiveness in dogs.
International archives of allergy and immunology 1995;107(1-3):239-41.
-
1995: Leal-Berumen I; O'Byrne P; Gupta A; Richards C D; Marshall J S
Prostanoid enhancement of interleukin-6 production by rat peritoneal mast cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(9):4759-67.
-
1995: Saroea H G; Inman M D; O'Byrne P M
U46619-induced bronchoconstriction in asthmatic subjects is mediated by acetylcholine release.
American journal of respiratory and critical care medicine 1995;151(2 Pt 1):321-4.
-
1994: Stevens W H; Adelroth E; Wattie J; Woolley M J; Ellis R; Dahlbäck M; O'Byrne P M
Effect of inhaled budesonide on ozone-induced airway hyperresponsiveness and bronchoalveolar lavage cells in dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;77(6):2578-83.
-
1994: Denburg J A; Woolley M; Leber B; Linden M; O'Byrne P
Basophil and eosinophil differentiation in allergic reactions.
The Journal of allergy and clinical immunology 1994;94(6 Pt 2):1135-41.
-
1994: O'Byrne P M; Hargreave F E
Non-invasive monitoring of airway inflammation.
American journal of respiratory and critical care medicine 1994;150(5 Pt 2):S100-2.
-
1994: Woolley M J; Denburg J A; Ellis R; Dahlback M; O'Byrne P M
Allergen-induced changes in bone marrow progenitors and airway responsiveness in dogs and the effect of inhaled budesonide on these parameters.
American journal of respiratory cell and molecular biology 1994;11(5):600-6.
-
1994: O'Byrne P M
Eicosanoids and asthma.
Annals of the New York Academy of Sciences 1994;744():251-61.
-
1994: Woolley K L; Adelroth E; Woolley M J; Ellis R; Jordana M; O'Byrne P M
Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1994;7(9):1576-84.
-
1994: Woolley M J; Wattie J; Ellis R; Lane C G; Stevens W H; Woolley K L; Dahlback M; O'Byrne P M
Effect of an inhaled corticosteroid on airway eosinophils and allergen-induced airway hyperresponsiveness in dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;77(3):1303-8.
-
1994: Takanaski S; Nonaka R; Xing Z; O'Byrne P; Dolovich J; Jordana M
Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils.
The Journal of experimental medicine 1994;180(2):711-5.
-
1994: Strban M; Manning P J; Watson R M; O'Byrne P M
Effect of magnitude of airway responsiveness and therapy with inhaled corticosteroid on histamine tachyphylaxis in asthma.
Chest 1994;105(5):1434-8.
-
1994: Melillo E; Woolley K L; Manning P J; Watson R M; O'Byrne P M
Effect of inhaled PGE2 on exercise-induced bronchoconstriction in asthmatic subjects.
American journal of respiratory and critical care medicine 1994;149(5):1138-41.
-
1994: Stevens W H; Lane C G; Woolley M J; Ellis R; Tagari P; Black C; Ford-Hutchinson A; O'Byrne P M
Effect of FLAP antagonist MK-0591 on leukotriene production and ozone-induced airway responses in dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;76(4):1583-8.
-
1994: Sterk P J; Fabbri L M; Quanjer P H; Cockcroft D W; O'Byrne P M; Anderson S D; Juniper E F; Malo J L
[Airway response. Standardized provocation tests in adults: pharmacological, physical and sensitizing stimuli. Work Group on Standardization of Respiratory Function Tests. European Community for Coal and Steel. Official position of the European Respiratory Society]
Revue des maladies respiratoires 1994;11 Suppl 3():53-83.
-
1994: O'Byrne P M; Adelroth E; Manning P J
Bronchial provocation with leukotrienes and other stimuli.
Advances in prostaglandin, thromboxane, and leukotriene research 1994;22():207-15.
-
1993: Manning P J; Watson R M; O'Byrne P M
Exercise-induced refractoriness in asthmatic subjects involves leukotriene and prostaglandin interdependent mechanisms.
The American review of respiratory disease 1993;148(4 Pt 1):950-4.
-
1993: Montaño L M; Jones G L; O'Byrne P M; Daniel E E
Effect of ozone exposure in vivo on response of bronchial rings in vitro: role of intracellular Ca2+.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(3):1315-22.
-
1993: Killian K J; Summers E; Watson R M; O'Byrne P M; Jones N L; Campbell E J
Factors contributing to dyspnoea during bronchoconstriction and exercise in asthmatic subjects.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1993;6(7):1004-10.
-
1993: Cockcroft D W; McParland C P; O'Byrne P M; Manning P; Friend J L; Rutherford B C; Swystun V A
Beclomethasone given after the early asthmatic response inhibits the late response and the increased methacholine responsiveness and cromolyn does not.
The Journal of allergy and clinical immunology 1993;91(6):1163-8.
-
1993: Freitag A; Watson R M; Matsos G; Eastwood C; O'Byrne P M
Effect of a platelet activating factor antagonist, WEB 2086, on allergen induced asthmatic responses.
Thorax 1993;48(6):594-8.
-
1993: Sterk P J; Fabbri L M; Quanjer P H; Cockcroft D W; O'Byrne P M; Anderson S D; Juniper E F; Malo J L
Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society.
The European respiratory journal. Supplement 1993;16():53-83.
-
1993: O'Byrne P M; Hargreave F E
Impact of monitoring inflammation on the management of adult asthmatic patients.
Allergy 1993;48(17 Suppl):153-7; discussion 162-3.
-
1992: Li Z; Daniel E E; Lane C G; Arnaout M A; O'Byrne P M
Effect of an anti-Mo1 MAb on ozone-induced airway inflammation and airway hyperresponsiveness in dogs.
The American journal of physiology 1992;263(6 Pt 1):L723-6.
-
1992: Wong B J; Dolovich J; Ramsdale E H; O'Byrne P; Gontovnick L; Denburg J A; Hargreave F E
Formoterol compared with beclomethasone and placebo on allergen-induced asthmatic responses.
The American review of respiratory disease 1992;146(5 Pt 1):1156-60.
-
1992: Manning P J; Watson R; O'Byrne P M
The effects of H2-receptor antagonists on exercise refractoriness in asthma.
The Journal of allergy and clinical immunology 1992;90(1):125-6.
-
1992: Jones G L; Saroea H G; Watson R M; O'Byrne P M
Effect of an inhaled thromboxane mimetic (U46619) on airway function in human subjects.
The American review of respiratory disease 1992;145(6):1270-4.
-
1992: Pin I; Freitag A P; O'Byrne P M; Girgis-Gabardo A; Watson R M; Dolovich J; Denburg J A; Hargreave F E
Changes in the cellular profile of induced sputum after allergen-induced asthmatic responses.
The American review of respiratory disease 1992;145(6):1265-9.
-
1992: Daniel E E; Abela A P; Janssen L J; O'Byrne P M
Effects of inflammatory mediators on canine airway neuromuscular function.
Canadian journal of physiology and pharmacology 1992;70(4):624-34.
-
1992: O'Byrne P M; Manning P J
Clinical relevance of lipid mediators in asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 1992;29(3):153-63.
-
1992: Jones G L; Lane C; O'Byrne P M
Effect of an inhaled thromboxane mimetic (U46619) on in vivo pulmonary resistance and airway hyperresponsiveness in dogs.
The Journal of physiology 1992;453():59-67.
-
1991: Matsui S; Jones G L; Woolley M J; Lane C G; Gontovnick L S; O'Byrne P M
The effect of antioxidants on ozone-induced airway hyperresponsiveness in dogs.
The American review of respiratory disease 1991;144(6):1287-90.
-
1991: Janssen L J; O'Byrne P M; Daniel E E
Mechanism underlying ozone-induced in vitro hyperresponsiveness in canine bronchi.
The American journal of physiology 1991;261(2 Pt 1):L55-62.
-
1991: O'Byrne P M; Ramsdale E H; Hargreave F E
Isocapnic hyperventilation for measuring airway hyperresponsiveness in asthma and in chronic obstructive pulmonary disease.
The American review of respiratory disease 1991;143(6):1444-5.
-
1991: Manning P J; Stevens W H; Cockcroft D W; O'Byrne P M
The role of thromboxane in allergen-induced asthmatic responses.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1991;4(6):667-72.
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1991: Ramsdale E H; Otis J; Kline P A; Gontovnick L S; Hargreave F E; O'Byrne P M
Prolonged protection against methacholine-induced bronchoconstriction by the inhaled beta 2-agonist formoterol.
The American review of respiratory disease 1991;143(5 Pt 1):998-1001.
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1991: Daniel E E; O'Byrne P
Effect of inflammatory mediators on airway nerves and muscle.
The American review of respiratory disease 1991;143(3 Pt 2):S3-5.
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1991: Gibson P G; Manning P J; O'Byrne P M; Girgis-Gabardo A; Dolovich J; Denburg J A; Hargreave F E
Allergen-induced asthmatic responses. Relationship between increases in airway responsiveness and increases in circulating eosinophils, basophils, and their progenitors.
The American review of respiratory disease 1991;143(2):331-5.
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1991: White A M; Stevens W H; Upton A R; O'Byrne P M; Collins S M
Airway responsiveness to inhaled methacholine in patients with irritable bowel syndrome.
Gastroenterology 1991;100(1):68-74.
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1990: Manning P J; Watson R M; Margolskee D J; Williams V C; Schwartz J I; O'Byrne P M
Inhibition of exercise-induced bronchoconstriction by MK-571, a potent leukotriene D4-receptor antagonist.
The New England journal of medicine 1990;323(25):1736-9.
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1990: Juniper E F; Kline P A; Vanzieleghem M A; Ramsdale E H; O'Byrne P M; Hargreave F E
Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1990;3(10):1122-7.
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1990: Juniper E F; Kline P A; Vanzieleghem M A; Ramsdale E H; O'Byrne P M; Hargreave F E
Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics.
The American review of respiratory disease 1990;142(4):832-6.
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1990: Jones G L; Lane C G; O'Byrne P M
Effect of thromboxane antagonists on ozone-induced airway responses in dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;69(3):880-4.
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1990: Stevens W H; Manning P J; Watson R M; O'Byrne P M
Tachyphylaxis to inhaled methacholine in normal but not asthmatic subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;69(3):875-9.
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1990: Juniper E F; Guyatt G H; O'Byrne P M; Viveiros M
Aqueous beclomethasone diproprionate nasal spray: regular versus "as required" use in the treatment of seasonal allergic rhinitis.
The Journal of allergy and clinical immunology 1990;86(3 Pt 1):380-6.
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1990: Manning P J; Rokach J; Malo J L; Ethier D; Cartier A; Girard Y; Charleson S; O'Byrne P M
Urinary leukotriene E4 levels during early and late asthmatic responses.
The Journal of allergy and clinical immunology 1990;86(2):211-20.
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1990: Inman M D; Watson R M; Killian K J; O'Byrne P M
Methacholine airway responsiveness decreases during exercise in asthmatic subjects.
The American review of respiratory disease 1990;141(6):1414-7.
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1990: Manning P J; Jones G L; Otis J; Daniel E E; O'Byrne P M
The inhibitory influence of tracheal mucosa mounted in close proximity to canine trachealis.
European journal of pharmacology 1990;178(1):85-9.
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1990: O'Byrne P M
Eicosanoids and inflammatory cells in asthma.
Agents and actions. Supplements 1990;31():85-101.
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1989: O'Byrne P M; Fuller R W
The role of thromboxane A2 in the pathogenesis of airway hyperresponsiveness.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1989;2(8):782-6.
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1989: Higgins D; O'Byrne P M
Comparison of isocapnic hyperventilation and histamine or methacholine inhalation for the assessment of airway responsiveness.
Allergy proceedings : the official journal of regional and state allergy societies 1989;10(5):317-21.
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1989: Kirby J G; Hargreave F E; Cockcroft D W; O'Byrne P M
Effect of indomethacin on allergen-induced asthmatic responses.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;66(2):578-83.
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1989: Manning P J; Lane C G; O'Byrne P M
The effect of oral prostaglandin E1 on airway responsiveness in asthmatic subjects.
Pulmonary pharmacology 1989;2(3):121-4.
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1988: Hamielec C M; Manning P J; O'Byrne P M
Exercise refractoriness after histamine inhalation in asthmatic subjects.
The American review of respiratory disease 1988;138(4):794-8.
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1988: Jackson P J; Manning P J; O'Byrne P M
A new role for histamine H2-receptors in asthmatic airways.
The American review of respiratory disease 1988;138(4):784-8.
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1988: Jones G L; Lane C G; Daniel E E; O'Byrne P M
Release of epithelium-derived relaxing factor after ozone inhalation in dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(3):1238-43.
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1988: Jones G L; O'Byrne P M; Pashley M; Serio R; Jury J; Lane C G; Daniel E E
Airway smooth muscle responsiveness from dogs with airway hyperresponsiveness after O3 inhalation.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(1):57-64.
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1988: Manning P J; O'Byrne P M
Histamine bronchoconstriction reduces airway responsiveness in asthmatic subjects.
The American review of respiratory disease 1988;137(6):1323-5.
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1988: O'Byrne P M
Allergen-induced airway hyperresponsiveness.
The Journal of allergy and clinical immunology 1988;81(1):119-27.
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1988: O'Byrne P M
Leukotrienes, airway hyperresponsiveness, and asthma.
Annals of the New York Academy of Sciences 1988;524():282-8.
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1988: O'Byrne P M; Jones G L; Lane C G; Pashley M; Daniel E E
Neural transmission during ozone-induced airway hyperresponsiveness.
Progress in clinical and biological research 1988;263():3-13.
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1988: Daniel E E; Serio R; Jury J; Pashley M; O'Byrne P
Effects of inflammatory mediators on neuromuscular transmission in canine trachea in vitro.
Progress in clinical and biological research 1988;263():167-76.
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1987: Manning P J; Jones G L; O'Byrne P M
Tachyphylaxis to inhaled histamine in asthmatic subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 1987;63(4):1572-7.
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1987: Jones G L; Lane C G; Manning P J; O'Byrne P M
Role of the parasympathetic nervous system in airway hyperresponsiveness after ozone inhalation.
Journal of applied physiology (Bethesda, Md. : 1985) 1987;63(3):1174-9.
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1985: O'Byrne P M; Thomson N C; Latimer K M; Roberts R S; Morris M M; Daniel E E; Hargreave F E
The effect of inhaled hexamethonium bromide and atropine sulphate on airway responsiveness to histamine.
The Journal of allergy and clinical immunology 1985;76(1):97-103.
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1983: Latimer K M; O'Byrne P M; Morris M M; Roberts R; Hargreave F E
Bronchoconstriction stimulated by airway cooling. Better protection with combined inhalation of terbutaline sulphate and cromolyn sodium than with either alone.
The American review of respiratory disease 1983;128(3):440-3.
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