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Timothy O'Connor

Research Profile

Activities & Behaviors

Smoking

Devices

Procedures

Anatomy

Disorders

Pulmonary Disease, Chronic Obstructive

Physiology

Living Beings

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Publications

TOP 3
Ann E Tilley; Xi Kathy Zhou; Nancy Amoroso; Andrew Clark; Neil R Hackett; Jason Mezey; Timothy P O'Connor; Larsson Omberg; Tina Raman; Jacqueline Salit; Yael Strulovici-Barel; RG Crystal
Biologic phenotyping of the human small airway epithelial response to cigarette smoking.
Meredith L Turetz; Timothy P O'Connor; Ann E Tilley; Yael Strulovici-Barel; Jacqueline Salit; David Dang; Matthew Teater; Jason Mezey; Andrew G Clark; Ronald G Crystal
Trachea epithelium as a "canary" for cigarette smoking-induced biologic phenotype of the small airway epithelium.
Holly Vanni; Angeliki Kazeros; Rui Wang; Ben-Gary Harvey; Barbara Ferris; Bishnu P De; Brendan J Carolan; Ralf-Harto Hübner; Timothy P O'Connor; Helen-Ann Brown Epstein
Cigarette smoking induces overexpression of a fat-depleting gene AZGP1 in the human.

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All Publications

2011: Ann E Tilley; Xi Kathy Zhou; Nancy Amoroso; Andrew Clark; Neil R Hackett; Jason Mezey; Timothy P O'Connor; Larsson Omberg; Tina Raman; Jacqueline Salit; Yael Strulovici-Barel; RG Crystal
Biologic phenotyping of the human small airway epithelial response to cigarette smoking.
PloS one 2011;6(7):e22798.
2009: Meredith L Turetz; Timothy P O'Connor; Ann E Tilley; Yael Strulovici-Barel; Jacqueline Salit; David Dang; Matthew Teater; Jason Mezey; Andrew G Clark; Ronald G Crystal
Trachea epithelium as a "canary" for cigarette smoking-induced biologic phenotype of the small airway epithelium.
Clinical and translational science 2009;2(4):260-72.
2009: Holly Vanni; Angeliki Kazeros; Rui Wang; Ben-Gary Harvey; Barbara Ferris; Bishnu P De; Brendan J Carolan; Ralf-Harto Hübner; Timothy P O'Connor; Helen-Ann Brown Epstein
Cigarette smoking induces overexpression of a fat-depleting gene AZGP1 in the human.
Chest 2009;135(5):1197-208.
2009: Ann E Tilley; Ben-Gary Harvey; Adriana Heguy; Neil R Hackett; Rui Wang; Timothy P O'Connor; Helen-Ann Brown Epstein
Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2009;179(6):457-66.
2009: Hiroki Saitoh; Philip L Leopold; Ben-Gary Harvey; Timothy P O'Connor; Stefan Worgall; Neil R Hackett; Ronald G Crystal
Emphysema mediated by lung overexpression of ADAM10.
Clinical and translational science 2009;2(1):50-6.
2009: Brendan J Carolan; Ben-Gary Harvey; Neil R Hackett; Timothy P O'Connor; Patricia A Cassano; Helen-Ann Brown Epstein
Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers.
Respiratory research 2009;10():111.
2009: Tina Raman; Timothy P O'Connor; Neil R Hackett; Wei Wang; Ben-Gary Harvey; Marc A Attiyeh; David T Dang; Matthew Teater; Helen-Ann Brown Epstein
Quality control in microarray assessment of gene expression in human airway epithelium.
BMC genomics 2009;10():493.
2008: Zeinab Ammous; Neil R Hackett; Marcus W Butler; Tina Raman; Igor Dolgalev; Timothy P O'Connor; Ben-Gary Harvey; Helen-Ann Brown Epstein
Variability in small airway epithelial gene expression among normal smokers.
Chest 2008;133(6):1344-53.
2007: Yael Strulovici; Philip L Leopold; Timothy P O'Connor; Robert Pergolizzi; Helen-Ann Brown Epstein
Human embryonic stem cells and gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(5):850-66.
2007: Brian D Gelbman; Adriana Heguy; Timothy P O'Connor; Joseph Zabner; Helen-Ann Brown Epstein
Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis.
Respiratory research 2007;8():10.
2007: Hiroyasu Kobayashi; Stefan Worgall; Timothy P O'Connor; Helen-Ann Brown Epstein
Interaction of Pneumocystis carinii with dendritic cells and resulting host responses to P. carinii.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(1):54-63.
2006: Toshiaki Fushimi; Timothy P O'Connor; Helen-Ann Brown Epstein
Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth.
Cancer research 2006;66(7):3513-22.
2006: Timothy P O'Connor; Helen-Ann Brown Epstein
Genetic medicines: treatment strategies for hereditary disorders.
Nature reviews. Genetics 2006;7(4):261-76.
2006: Adriana Heguy; Timothy P O'Connor; Karsta Luettich; Stefan Worgall; Adam Cieciuch; Ben-Gary Harvey; Neil R Hackett; Helen-Ann Brown Epstein
Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking.
Journal of molecular medicine (Berlin, Germany) 2006;84(4):318-28.
2005: Masahiro Mae; Timothy P O'Connor; Helen-Ann Brown Epstein
Gene transfer of the vascular endothelial growth factor receptor flt-1 suppresses pulmonary metastasis associated with lung growth.
American journal of respiratory cell and molecular biology 2005;33(6):629-35.
2005: Stefan Worgall; Adriana Heguy; Karsta Luettich; Timothy P O'Connor; Ben-Gary Harvey; Luis E N Quadri; Helen-Ann Brown Epstein
Similarity of gene expression patterns in human alveolar macrophages in response to Pseudomonas aeruginosa and Burkholderia cepacia.
Infection and immunity 2005;73(8):5262-8.
2003: Adriana Heguy; Ben-Gary Harvey; Timothy P O'Connor; Neil R Hackett; Helen-Ann Brown Epstein
Sampling-dependent up-regulation of gene expression in sequential samples of human airway epithelial cells.
Molecular medicine (Cambridge, Mass.) 2003;9(9-12):200-8.
2003: Neil R Hackett; Adriana Heguy; Ben-Gary Harvey; Timothy P O'Connor; Karsta Luettich; Douglas B Flieder; Rana Kaplan; Helen-Ann Brown Epstein
Variability of antioxidant-related gene expression in the airway epithelium of cigarette smokers.
American journal of respiratory cell and molecular biology 2003;29(3 Pt 1):331-43.