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Caitriona O'Driscoll

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J McCarthy; S Melgar; L Bourre; Raphael Darcy; G Hurley; J Ogier; M J O'Neill; A Quinlan; F Shanahan; D Walsh; Caitriona M O'Driscoll
Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system.
Jianfeng Guo; Woei Ping Cheng; Aoife M O'Mahony; Caitriona M O'Driscoll
Amphiphilic polyallylamine based polymeric micelles for siRNA delivery to the gastrointestinal tract: in vitro investigations.
Jianfeng Guo; James C Evans; Caitriona M O'Driscoll
Delivering RNAi therapeutics with non-viral technology: a promising strategy for prostate cancer?

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All Publications

2013: J McCarthy; S Melgar; L Bourre; Raphael Darcy; G Hurley; J Ogier; M J O'Neill; A Quinlan; F Shanahan; D Walsh; Caitriona M O'Driscoll
Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system.
Journal of controlled release : official journal of the Controlled Release Society 2013;168(1):28-34.
2013: Jianfeng Guo; Woei Ping Cheng; Aoife M O'Mahony; Caitriona M O'Driscoll
Amphiphilic polyallylamine based polymeric micelles for siRNA delivery to the gastrointestinal tract: in vitro investigations.
International journal of pharmaceutics 2013;447(1-2):150-7.
2013: Jianfeng Guo; James C Evans; Caitriona M O'Driscoll
Delivering RNAi therapeutics with non-viral technology: a promising strategy for prostate cancer?
Trends in molecular medicine 2013;19(4):250-61.
2013: Aoife M O'Mahony; Aoife Quinlan; Julien Ogier; John F Cryan; Raphael Darcy; Stephane Desgranges; Marc Devocelle; Caitriona M O'Driscoll
In vitro investigations of the efficacy of cyclodextrin-siRNA complexes modified with lipid-PEG-Octaarginine: towards a formulation strategy for non-viral neuronal siRNA delivery.
Pharmaceutical research 2013;30(4):1086-98.
2013: Valentina Villari; Caitriona M O'Driscoll; Raphael Darcy; Antonino Mazzaglia; Norberto Micali
Nanostructures of cationic amphiphilic cyclodextrin complexes with DNA.
Biomacromolecules 2013;14(3):811-7.
2013: Bruno M D C Godinho; Caitriona M O'Driscoll; Julien R Ogier; Raphael Darcy; John F Cryan
Self-assembling modified β-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease.
Molecular pharmaceutics 2013;10(2):640-9.
2012: A M O'Mahony; J F Cryan; Raphael Darcy; D Doyle; Caitriona M O'Driscoll
Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: effect of reversing primary and secondary face modifications.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;47(5):896-903.
2012: Anthony McMahon; Martin J O'Neill; Raphael Darcy; Ruth Donohue; Damien Forde; Eva Gomez; Caitriona M O'Driscoll
Targeted gene delivery to hepatocytes with galactosylated amphiphilic cyclodextrins.
The Journal of pharmacy and pharmacology 2012;64(8):1063-73.
2012: Aoife M O'Mahony; Julien Ogier; John F Cryan; Raphael Darcy; Stephane Desgranges; Caitriona M O'Driscoll
A click chemistry route to 2-functionalised PEGylated and cationic β-cyclodextrins: co-formulation opportunities for siRNA delivery.
Organic & biomolecular chemistry 2012;10(25):4954-60.
2011: B T Griffin; Caitriona M O'Driscoll
Opportunities and challenges for oral delivery of hydrophobic versus hydrophilic peptide and protein-like drugs using lipid-based technologies.
Therapeutic delivery 2011;2(12):1633-53.
2011: Francesca Doonan; Paul Kenna; Caitriona M O'Driscoll; Thomas G Cotter
Enhancing survival of photoreceptor cells in vivo using the synthetic progestin Norgestrel.
Journal of neurochemistry 2011;118(5):915-27.
2011: Caitriona M O'Driscoll; Nuria Sanvicens; Francesca Doonan; Angel Messeguer; Thomas G Cotter
A novel free radical scavenger rescues retinal cells in vivo.
Experimental eye research 2011;93(1):65-74.
2010: Jianfeng Guo; Karen A Fisher; Raphael Darcy; John F Cryan; Caitriona M O'Driscoll
Therapeutic targeting in the silent era: advances in non-viral siRNA delivery.
Molecular bioSystems 2010;6(7):1143-61.
2010: Waleed Faisal; Caitriona M O'Driscoll; Brendan T Griffin
Bioavailability of lycopene in the rat: the role of intestinal lymphatic transport.
The Journal of pharmacy and pharmacology 2010;62(3):323-31.
2009: Francesca Doonan; Deborah M Wallace; Caitriona M O'Driscoll; Thomas G Cotter
Rosiglitazone acts as a neuroprotectant in retinal cells via up-regulation of sestrin-1 and SOD-2.
Journal of neurochemistry 2009;109(2):631-43.
2008: Brendan T Griffin; Caitriona M O'Driscoll
An examination of the effect of intestinal first pass extraction on intestinal lymphatic transport of saquinavir in the rat.
Pharmaceutical research 2008;25(5):1125-33.
2008: Caitriona M O'Driscoll; Jeremy O'Connor; Colm J O'brien; Thomas G Cotter
Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo.
Journal of neurochemistry 2008;105(2):524-36.
2008: Caitriona M O'Driscoll; B T Griffin
Biopharmaceutical challenges associated with drugs with low aqueous solubility--the potential impact of lipid-based formulations.
Advanced drug delivery reviews 2008;60(6):617-24.
2007: Caitriona M O'Driscoll; Deborah Wallace; Thomas G Cotter
bFGF promotes photoreceptor cell survival in vitro by PKA-mediated inactivation of glycogen synthase kinase 3beta and CREB-dependent Bcl-2 up-regulation.
Journal of neurochemistry 2007;103(3):860-70.
2006: Caitriona M O'Driscoll; Maryanne Donovan; Thomas G Cotter
Analysis of apoptotic and survival mediators in the early post-natal and mature retina.
Experimental eye research 2006;83(6):1482-92.
2006: M Walsh; Mark Tangney; M J O'Neill; John O Larkin; Declan M Soden; Sharon L McKenna; Raphael Darcy; Gerald C O'Sullivan; Caitriona M O'Driscoll
Evaluation of cellular uptake and gene transfer efficiency of pegylated poly-L-lysine compacted DNA: implications for cancer gene therapy.
Molecular pharmaceutics 2006;3(6):644-53.
2006: Brendan T Griffin; Caitriona M O'Driscoll
A comparison of intestinal lymphatic transport and systemic bioavailability of saquinavir from three lipid-based formulations in the anaesthetised rat model.
The Journal of pharmacy and pharmacology 2006;58(7):917-25.
2005: Majella E Lane; Caitriona M O'Driscoll; Owen I Corrigan
Quantitative estimation of the effects of bile salt surfactant systems on insulin stability and permeability in the rat intestine using a mass balance model.
The Journal of pharmacy and pharmacology 2005;57(2):169-75.
2004: Fergal Seeballuck; Emma Lawless; Marianne B Ashford; Caitriona M O'Driscoll
Stimulation of triglyceride-rich lipoprotein secretion by polysorbate 80: in vitro and in vivo correlation using Caco-2 cells and a cannulated rat intestinal lymphatic model.
Pharmaceutical research 2004;21(12):2320-6.
2004: Sally-Ann Cryan; Ann Holohan; Ruth Donohue; Raphael Darcy; Caitriona M O'Driscoll
Cell transfection with polycationic cyclodextrin vectors.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;21(5):625-33.
2004: Karen England; Caitriona M O'Driscoll; Thomas G Cotter
Carbonylation of glycolytic proteins is a key response to drug-induced oxidative stress and apoptosis.
Cell death and differentiation 2004;11(3):252-60.
2003: Rachel H Gubbins; Caitriona M O'Driscoll; Owen I Corrigan
The effects of casein on diclofenac release from hydroxypropylmethylcellulose (HPMC) compacts.
International journal of pharmaceutics 2003;260(1):69-76.
2003: Fergal Seeballuck; Marianne B Ashford; Caitriona M O'Driscoll
The effects of pluronics block copolymers and Cremophor EL on intestinal lipoprotein processing and the potential link with P-glycoprotein in Caco-2 cells.
Pharmaceutical research 2003;20(7):1085-92.
2003: Owen I Corrigan; Rachel H Gubbins; Caitriona M O'Driscoll
Estimation of absorption parameters from the non-steady-state phase in the rat gut perfusion model.
The Journal of pharmacy and pharmacology 2003;55(4):487-93.
2003: Sally-Ann Cryan; Caitriona M O'Driscoll
Mechanistic studies on nonviral gene delivery to the intestine using in vitro differentiated cell culture models and an in vivo rat intestinal loop.
Pharmaceutical research 2003;20(4):569-75.
2002: Caitriona M O'Driscoll
Lipid-based formulations for intestinal lymphatic delivery.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(5):405-15.