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Reinhard Oertel

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Reinhard Oertel; Lisa Goltz; Wilhelm Kirch
Determination of the novel melatonin agonist Neu-P11 in plasma samples by liquid chromatography-tandem mass spectrometry.
Reinhard Oertel; J Pietsch; N Arenz; L Goltz; Wilhelm Kirch
Distribution of metoprolol in human autopsy material.
Joanna Gasch; Reinhard Oertel; Claudia S Leopold; Holger Knoth
Contamination of 0.2-micrometer infusion filters by N,N-dimethylacrylamide.

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All Publications

2013: Reinhard Oertel; Lisa Goltz; Wilhelm Kirch
Determination of the novel melatonin agonist Neu-P11 in plasma samples by liquid chromatography-tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis 2013;74():66-70.
2011: Reinhard Oertel; J Pietsch; N Arenz; L Goltz; Wilhelm Kirch
Distribution of metoprolol in human autopsy material.
Die Pharmazie 2011;66(2):115-8.
2010: Joanna Gasch; Reinhard Oertel; Claudia S Leopold; Holger Knoth
Contamination of 0.2-micrometer infusion filters by N,N-dimethylacrylamide.
Journal of critical care 2010;25(1):172.e9-14.
2009: Reinhard Oertel; Norman Arenz; Jörg Pietsch; Wilhelm Kirch
Simultaneous determination of three anticonvulsants using hydrophilic interaction LC-MS.
Journal of separation science 2009;32(2):238-43.
2008: Karen May; Thomas Giessmann; Danilo Wegner; Reinhard Oertel; Christiane Modess; Stefan Oswald; Manfred Braeter; Werner Siegmund
Oral absorption of propiverine solution and of the immediate and extended release dosage forms: influence of regioselective intestinal elimination.
European journal of clinical pharmacology 2008;64(11):1085-92.
2008: T Siepmann; Michael Mueck-Weymann; Reinhard Oertel; Wilhelm Kirch; D Pittrow; Martin Siepmann
The effects of venlafaxine on cognitive functions and quantitative EEG in healthy volunteers.
Pharmacopsychiatry 2008;41(4):146-50.
2008: B Kilian; Reinhard Oertel; Wilhelm Kirch
Determination of denaverine and its metabolites in urine samples by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A 2008;1189(1-2):339-46.
2008: Karen May; Kristin Westphal; Thomas Giessmann; Danilo Wegner; Ulrike Adam; Markus M Lerch; Reinhard Oertel; Rolf W Warzok; Werner Weitschies; Manfred Braeter; Werner Siegmund
Disposition and antimuscarinic effects of the urinary bladder spasmolytics propiverine: influence of dosage forms and circadian-time rhythms.
Journal of clinical pharmacology 2008;48(5):570-9.
2008: Christoph Schindler; C M Ferrario; C Jatzke; K Ahner; K Bridget Brosnihan; Peter Bramlage; Ulf Maywald; Reinhard Oertel; W Boecking; Wilhelm Kirch
Characterization of vascular reactivity in dorsal hand veins after oral rosiglitazone treatment in healthy subjects.
International journal of clinical pharmacology and therapeutics 2008;46(1):30-9.
2007: Reinhard Oertel; B Kilian; Werner Siegmund; Wilhelm Kirch
Determination of propiverine and its metabolites in rat samples by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A 2007;1149(1):121-6.
2007: Ute I Schwarz; H Hanso; Reinhard Oertel; Stephan Miehlke; Eberhard Kuhlisch; Hartmut Glaeser; Monika Hitzl; George K Dresser; Richard B Kim; Wilhelm Kirch
Induction of intestinal P-glycoprotein by St John's wort reduces the oral bioavailability of talinolol.
Clinical pharmacology and therapeutics 2007;81(5):669-78.
2007: Reinhard Oertel; W Kirch; E Klemm
Prednisolone concentration in the cochlea of patients with perilymph fistula.
Die Pharmazie 2007;62(3):239-40.
2007: Christoph Schindler; K Bridget Brosnihan; Carlos M Ferrario; Peter Bramlage; Ulf Maywald; Rainer Koch; Reinhard Oertel; Wilhelm Kirch
Comparison of inhibitory effects of irbesartan and atorvastatin treatment on the renin angiotensin system (RAS) in veins: a randomized double-blind crossover trial in healthy subjects.
Journal of clinical pharmacology 2007;47(1):112-20.
2007: Sebastian N Stehr; Jörg C Ziegeler; Annette Pexa; Reinhard Oertel; Andreas Deussen; Thea Koch; Matthias Hübler
The effects of lipid infusion on myocardial function and bioenergetics in l-bupivacaine toxicity in the isolated rat heart.
Anesthesia and analgesia 2007;104(1):186-92.
2005: Martin Siepmann; Kathrin Werner; Christoph Schindler; Reinhard Oertel; Wilhelm Kirch
The effects of bupropion on cognitive functions in healthy subjects.
Psychopharmacology 2005;182(4):597-8.
2005: Ulf D Renner; Reinhard Oertel; Wilhelm Kirch
Pharmacokinetics and pharmacodynamics in clinical use of scopolamine.
Therapeutic drug monitoring 2005;27(5):655-65.
2005: A Koehler; Reinhard Oertel; Wilhelm Kirch
Simultaneous determination of bupivacaine, mepivacain, prilocaine and ropivacain in human serum by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A 2005;1088(1-2):126-30.
2005: Sebastian N Stehr; Reinhard Oertel; Christoph Schindler; Matthias Hübler
Re: deterioration of Kearns-Sayre syndrome following articaine administration for local anesthesia.
Clinical neuropharmacology 2005;28(5):253.
2005: A Franka Nette; Getu Abraham; Fritz Rupert Ungemach; Reinhard Oertel; Wilhelm Kirch; Kirsten Leineweber; Friedrich-Wilhelm Mohr; Stefan Dhein
Interaction between simvastatin and metoprolol with respect to cardiac beta-adrenoceptor density, catecholamine levels and perioperative catecholamine requirements in cardiac surgery patients.
Naunyn-Schmiedeberg's archives of pharmacology 2005;372(2):115-24.
2005: Ute I Schwarz; Diana Seemann; Reinhard Oertel; Stephan Miehlke; Eberhard Kuhlisch; Martin F Fromm; Richard B Kim; David G Bailey; Wilhelm Kirch
Grapefruit juice ingestion significantly reduces talinolol bioavailability.
Clinical pharmacology and therapeutics 2005;77(4):291-301.
2004: Reinhard Oertel; Volker Neumeister; Wilhelm Kirch
Hydrophilic interaction chromatography combined with tandem-mass spectrometry to determine six aminoglycosides in serum.
Journal of chromatography. A 2004;1058(1-2):197-201.
2004: Matthias Grossmann; Gerhard Sattler; Hans Pistner; Reinhard Oertel; Klaus Richter; Stefan Schinzel; Laurent-Didier Jacobs
Pharmacokinetics of articaine hydrochloride in tumescent local anesthesia for liposuction.
Journal of clinical pharmacology 2004;44(11):1282-9.
2004: Reinhard Oertel; A Köhler; A Koster; W Kirch
Determination of Tirofiban in human serum by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;805(1):181-5.
2004: Reinhard Oertel; Ulf D Renner; Wilhelm Kirch
Determination of neomycin by LC-tandem mass spectrometry using hydrophilic interaction chromatography.
Journal of pharmaceutical and biomedical analysis 2004;35(3):633-8.
2002: Reinhard Oertel; Klaus Richter; J Fauler; Wilhelm Kirch
Increasing sample throughput in pharmacological studies by using dual-column liquid chromatography with tandem mass spectrometry.
Journal of chromatography. A 2002;948(1-2):187-92.
2001: Monika Krüger; Harald Achenbach; Bernd Terhaag; H Haase; K Richter; Reinhard Oertel; Rainer Preiss
Pharmacokinetics of oral talinolol following a single dose and during steady state in patients with chronic renal failure and healthy volunteers.
International journal of clinical pharmacology and therapeutics 2001;39(2):61-6.
2001: Reinhard Oertel; Klaus Richter; U Ebert; Wilhelm Kirch
Determination of scopolamine in human serum and microdialysis samples by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications 2001;750(1):121-8.
2001: U Ebert; Matthias Grossmann; Reinhard Oertel; T Gramatté; Wilhelm Kirch
Pharmacokinetic-pharmacodynamic modeling of the electroencephalogram effects of scopolamine in healthy volunteers.
Journal of clinical pharmacology 2001;41(1):51-60.
2000: U Ebert; Reinhard Oertel; Wilhelm Kirch
Influence of grapefruit juice on scopolamine pharmacokinetics and pharmacodynamics in healthy male and female subjects.
International journal of clinical pharmacology and therapeutics 2000;38(11):523-31.
2000: K Westphal; Anita Weinbrenner; Michael Zschiesche; Gerd Franke; M Knoke; Reinhard Oertel; P Fritz; Oliver Von Richter; Rolf Warzok; Thomas Hachenberg; Hans-Martin Kauffmann; Dieter Schrenk; Bernd Terhaag; Heyo K Kroemer; Werner Siegmund
Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction.
Clinical pharmacology and therapeutics 2000;68(4):345-55.
2000: U Ebert; N Q Thong; Reinhard Oertel; Wilhelm Kirch
Effects of rifampicin and cimetidine on pharmacokinetics and pharmacodynamics of lamotrigine in healthy subjects.
European journal of clinical pharmacology 2000;56(4):299-304.
2000: K Westphal; Anita Weinbrenner; Thomas Giessmann; M Stuhr; Gerd Franke; Michael Zschiesche; Reinhard Oertel; Bernd Terhaag; Heyo K Kroemer; Werner Siegmund
Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein.
Clinical pharmacology and therapeutics 2000;68(1):6-12.
2000: U Ebert; Reinhard Oertel; Wilhelm Kirch
Physostigmine reversal of midazolam-induced electroencephalographic changes in healthy subjects.
Clinical pharmacology and therapeutics 2000;67(5):538-48.
2000: Ute I Schwarz; T Gramatté; Jutta Krappweis; Reinhard Oertel; Wilhelm Kirch
P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans.
International journal of clinical pharmacology and therapeutics 2000;38(4):161-7.
1999: Reinhard Oertel; U Ebert; R Rahn; W Kirch
The effect of age on pharmacokinetics of the local anesthetic drug articaine.
Regional anesthesia and pain medicine 1999;24(6):524-8.
1999: T Gramatté; Reinhard Oertel
Intestinal secretion of intravenous talinolol is inhibited by luminal R-verapamil.
Clinical pharmacology and therapeutics 1999;66(3):239-45.
1999: Reinhard Oertel; Klaus Richter; U Ebert
[A rapid and sensitive HPLC method for determination of lamotrigine in serum].
Die Pharmazie 1999;54(8):628-9.
1999: Reinhard Oertel; Klaus Richter; Wilhelm Kirch
Sensitive method for the determination of the antiarrhythmic drug detajmium in serum by solid-phase extraction and high-performance liquid chromatography with fluorimetric detection.
Journal of chromatography. A 1999;846(1-2):217-22.
1999: Klaus Richter; Reinhard Oertel
Solid-phase extraction and high-performance liquid chromatographic determination of articainic and its metabolite articainic acid in human serum.
Journal of chromatography. B, Biomedical sciences and applications 1999;724(1):109-15.
1999: Ute I Schwarz; T Gramatté; Jutta Krappweis; A Berndt; Reinhard Oertel; Oliver Von Richter; Wilhelm Kirch
Unexpected effect of verapamil on oral bioavailability of the beta-blocker talinolol in humans.
Clinical pharmacology and therapeutics 1999;65(3):283-90.
1998: Reinhard Oertel; Klaus Richter
Plasma protein binding of the local anaesthetic drug articaine and its metabolite articainic acid.
Die Pharmazie 1998;53(9):646-7.
1998: U Ebert; Martin Siepmann; Reinhard Oertel; K A Wesnes; Wilhelm Kirch
Pharmacokinetics and pharmacodynamics of scopolamine after subcutaneous administration.
Journal of clinical pharmacology 1998;38(8):720-6.
1998: Reinhard Oertel; Klaus Richter; T Gramatté; Wilhelm Kirch
Determination of drugs in biological fluids by high-performance liquid chromatography with on-line sample processing.
Journal of chromatography. A 1998;797(1-2):203-9.
1997: Reinhard Oertel; R Rahn; W Kirch
Clinical pharmacokinetics of articaine.
Clinical pharmacokinetics 1997;33(6):417-25.
1996: Reinhard Oertel; A Berndt; Wilhelm Kirch
Saturable in vitro metabolism of articaine by serum esterases. Does it contribute to the persistence of the local anesthetic effect?
Regional anesthesia 1996;21(6):576-81.
1996: Reinhard Oertel; Klaus Richter; U Ebert; Wilhelm Kirch
Determination of scopolamine in human serum by gas chromatography-ion trap tandem mass spectrometry.
Journal of chromatography. B, Biomedical applications 1996;682(2):259-64.
1996: T Gramatté; Reinhard Oertel; B Terhaag; Wilhelm Kirch
Direct demonstration of small intestinal secretion and site-dependent absorption of the beta-blocker talinolol in humans.
Clinical pharmacology and therapeutics 1996;59(5):541-9.
1996: Klaus Richter; Reinhard Oertel; Wilhelm Kirch
New sensitive method for the determination of hydrochlorothiazide in human serum by high-performance liquid chromatography with electrochemical detection.
Journal of chromatography. A 1996;729(1-2):293-6.
1995: A Berndt; C Hoffmann; Klaus Richter; Reinhard Oertel; A Vierkant; W Siegmund
Tiracizine disposition in healthy volunteers with reference to the debrisoquine oxidation phenotype.
British journal of clinical pharmacology 1995;40(3):287-8.
1995: A Berndt; Reinhard Oertel; B Terhaag; Klaus Richter; T Gramatté
Pharmacokinetics of the antiarrhythmic agent tiracizine: steady state kinetics in comparison with single-dose kinetics.
Biopharmaceutics & drug disposition 1995;16(5):427-41.
1995: B Trausch; Reinhard Oertel; Klaus Richter; T Gramatté
Disposition and bioavailability of the beta 1-adrenoceptor antagonist talinolol in man.
Biopharmaceutics & drug disposition 1995;16(5):403-14.
1995: A Berndt; T Gramatté; Reinhard Oertel; B Terhaag; Klaus Richter; Wilhelm Kirch
Day-night variations in the renal excretion of the antiarrhythmic agent tiracizine and its metabolites.
Chronobiology international 1995;12(2):135-40.
1995: D Dobrev; A Berndt; Reinhard Oertel; Klaus Richter; B Terhaag; T Gramatté
[The bioequivalence of metoclopramide in two tablet formulations].
Arzneimittel-Forschung 1995;45(3):304-6.
1995: A Berndt; Reinhard Oertel; Klaus Richter; B Terhaag; T Gramatté
[Relative bioavailability of the antiarrhythmia agent, tiracizine and its metabolites].
Arzneimittel-Forschung 1995;45(3):250-3.
1995: B Trausch; Reinhard Oertel; Klaus Richter; T Gramatté
[The protein binding of talinolol].
Die Pharmazie 1995;50(1):72.
1994: Reinhard Oertel; Klaus Richter; B Trausch; A Berndt; T Gramatté; Wilhelm Kirch
Elucidation of the structure of talinolol metabolites in man. Determination of talinolol and hydroxylated talinolol metabolites in urine and analysis of talinolol in serum.
Journal of chromatography. B, Biomedical applications 1994;660(2):353-63.
1994: A Berndt; T Gramatté; Reinhard Oertel; Klaus Richter; B Terhaag; Wilhelm Kirch
Dose dependent tiracizine disposition in healthy volunteers: serum and urine kinetics and dose related ECG-changes.
European journal of drug metabolism and pharmacokinetics 1994;19(4):359-68.
1994: Reinhard Oertel; Klaus Richter; D Dobrev; A Berndt; T Gramatté
[A sensitive HPLC-method for determination of triamterene in serum].
Die Pharmazie 1994;49(9):700-2.
1994: Reinhard Oertel; Klaus Richter; B Trausch; T Gramatté
[A quick, simple HPLC method for determination of talinolol in serum].
Die Pharmazie 1994;49(4):291-2.
1994: Reinhard Oertel; A Oertel; K Weile; T Gramatté; K Feller
[The concentration of local anesthetics in the dental alveolus. Comparative studies of lidocaine and articaine in the mandible and maxilla].
Schweizer Monatsschrift für Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia / SSO 1994;104(8):952-5.
1993: Reinhard Oertel; Klaus Richter; K Weile; T Gramatté; A Berndt; K Feller
A simple method for the determination of articaine and its metabolite articainic acid in dentistry: application to a comparison of articaine and lidocaine concentrations in alveolus blood.
Methods and findings in experimental and clinical pharmacology 1993;15(8):541-7.
1993: Reinhard Oertel; A Oertel; K Feller
A new method of blood sampling and determination of the local anesthetic agent lidocaine in dentistry.
Methods and findings in experimental and clinical pharmacology 1993;15(2):131-6.
1992: B Trausch; B Terhaag; M Gebhardt; Klaus Richter; Reinhard Oertel
The biliary and renal elimination of the new muscarinic-1-antagonist AWD 26-06 in volunteers with T-tube after cholecystectomy.
International journal of clinical pharmacology, therapy, and toxicology 1992;30(11):508-9.
1992: B Terhaag; U Palm; H Sahre; Klaus Richter; Reinhard Oertel
Interaction of talinolol and sulfasalazine in the human gastrointestinal tract.
European journal of clinical pharmacology 1992;42(4):461-2.
1991: Reinhard Oertel; B Terhaag; Klaus Richter
[In vitro interactions of talinolol with propranolol and salazosulfapyridine].
Die Pharmazie 1991;46(12):887-8.