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Franz Oesch

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
57
Hengstler, Jan
38
Arand, Michael
32
Steinberg, P
31
Platt, Karl
26
Friedberg, Thomas
24
Oesch-Bartlomowicz, Barbara
24
Glatt, Hansruedi
19
wieser, raimund
18
Dietrich, Cornelia
17
Tanner, Berno
12
Doehmer, Johannes
11
Faust, Dagmar
10
Fuchs, Jürgen
8
Gebhard, Susanne
8
Dienes, Hans

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Publications

TOP 3
Finkenwirth P; Spelmeyer U; Hommel G; Rose D-M; Jung D; Rossbach B; Mayer-Popken O; Platt K-L; Oesch F; Muttray A
Effects of an acute exposure to toluene on the DNA repair activity of the human 8-oxoguanine DNA glycosylase 1 (hOGG1) in healthy subjects.
Schreck Ilona; Chudziak Doreen; Schneider Sandra; Seidel Albrecht; Platt Karl L; Oesch Franz; Weiss Carsten
Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells.
Landsiedel Robert; Kapp Maike Diana; Schulz Markus; Wiench Karin; Oesch Franz
Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers.

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All Publications

2009: Finkenwirth P; Spelmeyer U; Hommel G; Rose D-M; Jung D; Rossbach B; Mayer-Popken O; Platt K-L; Oesch F; Muttray A
Effects of an acute exposure to toluene on the DNA repair activity of the human 8-oxoguanine DNA glycosylase 1 (hOGG1) in healthy subjects.
Archives of toxicology 2009;83(8):777-84.
2009: Schreck Ilona; Chudziak Doreen; Schneider Sandra; Seidel Albrecht; Platt Karl L; Oesch Franz; Weiss Carsten
Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells.
Toxicology 2009;259(3):91-6.
2009: Landsiedel Robert; Kapp Maike Diana; Schulz Markus; Wiench Karin; Oesch Franz
Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers.
Mutation research 2009;681(2-3):241-58.
2009: Oesch-Bartlomowicz Barbara; Oesch Franz
Role of cAMP in mediating AHR signaling.
Biochemical pharmacology 2009;77(4):627-41.
2009: Watelet Jean-Baptiste; Benedetti Margherita Strolin; Church Martin K; Oesch Franz
General conclusions.
Drug metabolism reviews 2009;41(3):528-9.
2009: Oesch Franz
Importance of knowledge on drug metabolism for the safe use of drugs in humans.
Drug metabolism reviews 2009;41(3):298-300.
2008: Oesch Franz; Dietrich Cornelia; Naegeli Hanspeter; Schwarz Michael; van der Horst Gijsbertus; Zanger Ulrich; Oesch Barbara; Weiss Carsten
New aspects on mechanisms of chemical carcinogenesis: emphasis on species and gender/sex differences and developmental/aging determinants.
Archives of toxicology 2008;82(11):875-80.
2008: Oesch-Bartlomowicz B; Oesch F
Phosphorylation of xenobiotic-metabolizing cytochromes P450.
Analytical and bioanalytical chemistry 2008;392(6):1085-92.
2008: Weiss C; Faust D; Schreck I; Ruff A; Farwerck T; Melenberg A; Schneider S; Oesch-Bartlomowicz B; Zatloukalová J; Vondrácek J; Oesch F; Dietrich C
TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A.
Oncogene 2008;27(15):2198-207.
2007: Carmo Helena; Brulport Marc; Hermes Matthias; Oesch Franz; de Boer Douwe; Remião Fernando; Carvalho Félix; Schön Michael R; Krebsfaenger Niels; Doehmer Johannes; Bastos Maria de Lourdes; Hengstler Jan G
CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA).
Toxicology 2007;229(3):236-44.
2007: Oesch Franz; Fabian Eric; Oesch-Bartlomowicz Barbara; Werner Christoph; Landsiedel Robert
Drug-metabolizing enzymes in the skin of man, rat, and pig.
Drug metabolism reviews 2007;39(4):659-98.
2006: Carmo Helena; Brulport Marc; Hermes Matthias; Oesch Franz; Silva Renata; Ferreira Luísa M; Branco Paula S; Boer Douwe de; Remião Fernando; Carvalho Félix; Schön Michael R; Krebsfaenger Niels; Doehmer Johannes; Bastos Maria de Lourdes; Hengstler Jan G
Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity.
Pharmacogenetics and genomics 2006;16(11):789-99.
2006: Hausherr Carolin K; Schiffer Ilka B; Gebhard Susanne; Banic Andreas; Tanner Berno; Kolbl Heinz; Thoenes Eric; Beckers Thomas; Spangenberg Christian; Prawitt Dirk; Trost Tatjana; Zabel Bernhard; Oesch Franz; Hermes Matthias; Hengstler Jan G
Dephosphorylation of p-ERK1/2 in relation to tumor remission after HER-2 and Raf1 blocking therapy in a conditional mouse tumor model.
Molecular carcinogenesis 2006;45(5):302-8.
2006: Vodicka Pavel; Koskinen Mikko; Naccarati Alessio; Oesch-Bartlomowicz Barbara; Vodickova Ludmila; Hemminki Kari; Oesch Franz
Styrene metabolism, genotoxicity, and potential carcinogenicity.
Drug metabolism reviews 2006;38(4):805-53.
2005: Oesch-Bartlomowicz B; Oesch F
Phosphorylation of cytochromes P450: first discovery of a posttranslational modification of a drug-metabolizing enzyme.
Biochemical and biophysical research communications 2005;338(1):446-9.
2005: Faust Dagmar; Dolado Ignacio; Cuadrado Ana; Oesch Franz; Weiss Carsten; Nebreda Angel R; Dietrich Cornelia
p38alpha MAPK is required for contact inhibition.
Oncogene 2005;24(53):7941-5.
2005: Weiss Carsten; Faust Dagmar; Dürk Heike; Kolluri Siva Kumar; Pelzer Anke; Schneider Sandra; Dietrich Cornelia; Oesch Franz; Göttlicher Martin
TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38-MAPK-dependent pathway.
Oncogene 2005;24(31):4975-83.
2005: Hengstler Jan G; Brulport Marc; Schormann Wiebke; Bauer Alexander; Hermes Matthias; Nussler Andreas K; Fandrich Fred; Ruhnke Maren; Ungefroren Hendrik; Griffin Louise; Bockamp Ernesto; Oesch Franz; von Mach Marc-Alexander
Generation of human hepatocytes by stem cell technology: definition of the hepatocyte.
Expert opinion on drug metabolism & toxicology 2005;1(1):61-74.
2005: Oesch-Bartlomowicz Barbara; Huelster Andrea; Wiss Oliver; Antoniou-Lipfert Patricia; Dietrich Cornelia; Arand Michael; Weiss Carsten; Bockamp Ernesto; Oesch Franz
Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9218-23.
2005: Hoelper Peter; Faust Dagmar; Oesch Franz; Dietrich Cornelia
Evaluation of the role of c-Src and ERK in TCDD-dependent release from contact-inhibition in WB-F344 cells.
Archives of toxicology 2005;79(4):201-7.
2005: Ringel M; von Mach M A; Santos R; Feilen P J; Brulport M; Hermes M; Bauer A W; Schormann W; Tanner B; Schön M R; Oesch F; Hengstler J G
Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction.
Toxicology 2005;206(1):153-67.
2005: Carmo Helena; Hengstler Jan G; de Boer Douwe; Ringel Michael; Remião Fernando; Carvalho Félix; Fernandes Eduarda; dos Reys Lesseps A; Oesch Franz; de Lourdes Bastos Maria
Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): analysis of phase I metabolism with hepatocytes of six species including human.
Toxicology 2005;206(1):75-89.
2005: Hoelper Peter; Faust Dagmar; Oesch Franz; Dietrich Cornelia
Transforming growth factor-beta1 is not involved in TCDD-dependent release from contact inhibition in WB-F344 cells.
Archives of toxicology 2005;79(1):31-6.
2004: Hoelper Peter; Faust Dagmar; Oesch Franz; Dietrich Cornelia
Transforming growth factor beta1 is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-dependent release from contact-inhibition in WB-F344 cells.
Archives of toxicology 2004;78(11):643-8.
2004: Reder-Hilz B; Ullrich M; Ringel M; Hewitt N; Utesch D; Oesch F; Hengstler J G
Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(4):408-17.
2004: Oesch-Bartlomowicz Barbara; Janssen Kai; Wiss Oliver; Oesch Franz
Guanine 6-O-methylation pattern within the dioxin responsive element of the CYP1A1 enhancer shows two critical guanines for AhR/ARNT binding.
Chemistry & biodiversity 2004;1(3):473-80.
2004: Oesch-Bartlmowicz Barbara; Oesch Franz
Modulation of mutagenicity by phosphorylation of mutagen-metabolizing enzymes.
Archives of biochemistry and biophysics 2004;423(1):31-6.
2004: Tanner Berno; Grimme Stephan; Schiffer Ilka; Heimerdinger Carolin; Schmidt Markus; Dutkowski Philipp; Neubert Susanne; Oesch Franz; Franzen Arno; Kölbl Heinz; Fritz Gerhard; Kaina Bernd; Hengstler Jan Georg
Nuclear expression of apurinic/apyrimidinic endonuclease increases with progression of ovarian carcinomas.
Gynecologic oncology 2004;92(2):568-77.
2004: Carmo Helena; Hengstler Jan G; de Boer Douwe; Ringel Michael; Carvalho Félix; Fernandes Eduarda; Remião Fernando; dos Reys Lesseps A; Oesch Franz; de Lourdes Bastos Maria
Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(2):198-205.
2004: Oesch Franz; Hengstler Jan Georg; Arand Michael
Detoxication strategy of epoxide hydrolase-the basis for a novel threshold for definable genotoxic carcinogens.
Nonlinearity in biology, toxicology, medicine 2004;2(1):21-6.
2004: Prawitt D; Brixel L; Spangenberg C; Eshkind L; Heck R; Oesch F; Zabel B; Bockamp E
RNAi knock-down mice: an emerging technology for post-genomic functional genetics.
Cytogenetic and genome research 2004;105(2-4):412-21.
2003: Arand Michael; Cronin Annette; Oesch Franz; Mowbray Sherry L; Jones T Alwyn
The telltale structures of epoxide hydrolases.
Drug metabolism reviews 2003;35(4):365-83.
2003: Schiffer Ilka B; Gebhard Susanne; Heimerdinger Carolin K; Heling Annette; Hast Jochem; Wollscheid Ursula; Seliger Barbara; Tanner Berno; Gilbert Sandra; Beckers Thomas; Baasner Silke; Brenner Walburgis; Spangenberg Christian; Prawitt Dirk; Trost Tatjana; Schreiber Wolfgang G; Zabel Bernhard; Thelen Manfred; Lehr Hans-Anton; Oesch Franz; Hengstler Jan G
Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission.
Cancer research 2003;63(21):7221-31.
2003: Arand Michael; Hallberg B Martin; Zou Jinyu; Bergfors Terese; Oesch Franz; van der Werf Mariët J; de Bont Jan A M; Jones T Alwyn; Mowbray Sherry L
Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site.
The EMBO journal 2003;22(11):2583-92.
2003: Gebhardt Rolf; Hengstler Jan G; Müller Dieter; Glöckner Reinhild; Buenning Peter; Laube Britta; Schmelzer Eva; Ullrich Martina; Utesch Dietmar; Hewitt Nicola; Ringel Michael; Hilz Beate Reder; Bader Augustinus; Langsch Angelika; Koose Thomas; Burger Hans-Jörg; Maas Jochen; Oesch Franz
New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures.
Drug metabolism reviews 2003;35(2-3):145-213.
2003: Schiffer Ilka B; Schreiber Wolfgang G; Graf Robert; Schreiber Elke M; Jung Detlev; Rose Dirk M; Hehn Manfred; Gebhard Susanne; Sagemüller Jens; Spiess Hans W; Oesch Franz; Thelen Manfred; Hengstler Jan G
No influence of magnetic fields on cell cycle progression using conditions relevant for patients during MRI.
Bioelectromagnetics 2003;24(4):241-50.
2003: Cronin Annette; Mowbray Sherry; Dürk Heike; Homburg Shirli; Fleming Ingrid; Fisslthaler Beate; Oesch Franz; Arand Michael
The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1552-7.
2003: Dietrich Cornelia; Faust Dagmar; Moskwa Matthias; Kunz Anja; Bock Karl-Walter; Oesch Franz
TCDD-dependent downregulation of gamma-catenin in rat liver epithelial cells (WB-F344).
International journal of cancer. Journal international du cancer 2003;103(4):435-9.
2003: Micke Patrick; Basrai Maryam; Faldum Andreas; Bittinger Fernando; Rönnstrand Lars; Blaukat Andree; Beeh Kai Michael; Oesch Franz; Fischer Berthold; Buhl Roland; Hengstler Jan Georg
Characterization of c-kit expression in small cell lung cancer: prognostic and therapeutic implications.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):188-94.
2003: Hengstler Jan G; Bolm-Audorff Ulrich; Faldum Andreas; Janssen Kai; Reifenrath Michael; Götte Walter; Jung Detlev; Mayer-Popken Otfried; Fuchs Jürgen; Gebhard Susanne; Bienfait Heinz Günter; Schlink Kirsten; Dietrich Cornelia; Faust Dagmar; Epe Bernd; Oesch Franz
Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected.
Carcinogenesis 2003;24(1):63-73.
2003: Oesch-Bartlomowicz Barbara; Oesch Franz
Cytochrome-P450 phosphorylation as a functional switch.
Archives of biochemistry and biophysics 2003;409(1):228-34.
2002: Bockamp Ernesto; Maringer Marko; Spangenberg Christian; Fees Stephan; Fraser Stuart; Eshkind Leonid; Oesch Franz; Zabel Bernhard
Of mice and models: improved animal models for biomedical research.
Physiological genomics 2002;11(3):115-32.
2002: Oesch-Bartlomowicz Barbara; Oesch Franz
Fast regulation of cytochrome P450 activities by phosphorylation and consequences for drug metabolism and toxicity.
Biological chemistry 2002;383(10):1587-92.
2002: Dietrich C; Faust D; Budt S; Moskwa M; Kunz A; Bock K-W; Oesch F
2,3,7,8-tetrachlorodibenzo-p-dioxin-dependent release from contact inhibition in WB-F344 cells: involvement of cyclin A.
Toxicology and applied pharmacology 2002;183(2):117-26.
2002: Ringel M; Oesch F; Gerl M; Klebach M; Quint M; Bader A; Böttger T; Hengstler J G
Permissive and suppressive effects of dexamethasone on enzyme induction in hepatocyte co-cultures.
Xenobiotica; the fate of foreign compounds in biological systems 2002;32(8):653-66.
2002: Vodicka Pavel; Koskinen Mikko; Arand Michael; Oesch Franz; Hemminki Kari
Spectrum of styrene-induced DNA adducts: the relationship to other biomarkers and prospects in human biomonitoring.
Mutation research 2002;511(3):239-54.
2002: Beerheide W; von Mach M A; Ringel M; Fleckenstein C; Schumann S; Renzing N; Hildebrandt A; Brenner W; Jensen O; Gebhard S; Reifenberg K; Bender J; Oesch F; Hengstler J G
Downregulation of beta2-microglobulin in human cord blood somatic stem cells after transplantation into livers of SCID-mice: an escape mechanism of stem cells?
Biochemical and biophysical research communications 2002;294(5):1052-63.
2002: Hast J; Schiffer I B; Neugebauer B; Teichman E; Schreiber W; Brieger J; Kim D W; Gebhard S; Born C J; Strugala M; Sagemüller J; Brenner W; Mann W J; Oesch F; Thelen M; Hengstler J G
Angiogenesis and fibroblast proliferation precede formation of recurrent tumors after radiation therapy in nude mice.
Anticancer research 2002;22(2A):677-88.
2002: Dietrich Cornelia; Scherwat Julia; Faust Dagmar; Oesch Franz
Subcellular localization of beta-catenin is regulated by cell density.
Biochemical and biophysical research communications 2002;292(1):195-9.
2001: Schreiber W G; Teichmann E M; Schiffer I; Hast J; Akbari W; Georgi H; Graf R; Hehn M; Spiebeta H W; Thelen M; Oesch F; Hengstler J G
Lack of mutagenic and co-mutagenic effects of magnetic fields during magnetic resonance imaging.
Journal of magnetic resonance imaging : JMRI 2001;14(6):779-88.
2001: Oesch-Bartlomowicz B; Richter B; Becker R; Vogel S; Padma P R; Hengstler J G; Oesch F
cAMP-dependent phosphorylation of CYP2B1 as a functional switch for cyclophosphamide activation and its hormonal control in vitro and in vivo.
International journal of cancer. Journal international du cancer 2001;94(5):733-42.
2001: Heit I; Wieser R J; Herget T; Faust D; Borchert-Stuhlträger M; Oesch F; Dietrich C
Involvement of protein kinase Cdelta in contact-dependent inhibition of growth in human and murine fibroblasts.
Oncogene 2001;20(37):5143-54.
2001: Janssen K; Schlink K; Götte W; Hippler B; Kaina B; Oesch F
DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326.
Mutation research 2001;486(3):207-16.
2001: Janssen K; Eichhorn-Grombacher U; Schlink K; Nitzsche S; Oesch F; Kaina B
Long-time expression of DNA repair enzymes MGMT and APE in human peripheral blood mononuclear cells.
Archives of toxicology 2001;75(5):306-12.
2001: Micke P; Hengstler J G; Ros R; Bittinger F; Metz T; Gebhard S; Beeh K M; Oesch F; Buhl R
c-erbB-2 expression in small-cell lung cancer is associated with poor prognosis.
International journal of cancer. Journal international du cancer 2001;92(4):474-9.
2001: Härtter S; Wang X; Weigmann H; Friedberg T; Arand M; Oesch F; Hiemke C
Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin.
Journal of clinical psychopharmacology 2001;21(2):167-74.
2001: Dietrich C; Gumpert N; Heit I; Borchert-Stuhlträger M; Oesch F; Wieser R
Rottlerin induces a transformed phenotype in human keratinocytes.
Biochemical and biophysical research communications 2001;282(2):575-9.
2001: Hengstler J G; Pilch H; Schmidt M; Dahlenburg H; Sagemüller J; Schiffer I; Oesch F; Knapstein P G; Kaina B; Tanner B
Metallothionein expression in ovarian cancer in relation to histopathological parameters and molecular markers of prognosis.
International journal of cancer. Journal international du cancer 2001;95(2):121-7.
2001: Oesch F; Herrero M E; Lohmann M; Hengstler J G; Arand M
Sequestration of biological reactive intermediates by trapping as covalent enzyme-intermediate complex.
Advances in experimental medicine and biology 2001;500():577-86.
2000: Hengstler J G; Bauer A; Wolf H K; Bulitta C J; Tanner B; Oesch F; Gebhard S; Boettger T
Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer.
Anticancer research 2000;20(5A):2967-74.
2000: Hewitt N J; Fischer T; Zuehlke U; Oesch F; Utesch D
Metabolic activity of fresh and cryopreserved cynomolgus monkey (Macaca fascicularis) hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 2000;30(7):665-81.
2000: Oesch F; Herrero M E; Hengstler J G; Lohmann M; Arand M
Metabolic detoxification: implications for thresholds.
Toxicologic pathology 2000;28(3):382-7.
2000: Hengstler J G; Bockisch A; Fuchs J; Grimm W; Görges R; Oesch-Bartlomowicz B; Zapf A O; Lade K; Tanner B; Teichmann E; Thelen M; Gebhard S; Oesch F
Induction of DNA single-strand breaks by 131I and 99mTc in human mononuclear blood cells in vitro and extrapolation to the in vivo situation.
Radiation research 2000;153(5 Pt 1):512-20.
2000: Kienast K; Kaes C; Drumm K; Buhl R; Micke P; Oesch F; Hengstler J G
Asbestos-exposed blood monocytes--deoxyribonucleic acid strand lesions in co-cultured bronchial epithelial cells.
Scandinavian journal of work, environment & health 2000;26(1):71-7.
2000: Hengstler J G; Ringel M; Biefang K; Hammel S; Milbert U; Gerl M; Klebach M; Diener B; Platt K L; Böttger T; Steinberg P; Oesch F
Cultures with cryopreserved hepatocytes: applicability for studies of enzyme induction.
Chemico-biological interactions 2000;125(1):51-73.
2000: Hengstler J G; Utesch D; Steinberg P; Platt K L; Diener B; Ringel M; Swales N; Fischer T; Biefang K; Gerl M; Böttger T; Oesch F
Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction.
Drug metabolism reviews 2000;32(1):81-118.
2000: Zou J; Hallberg B M; Bergfors T; Oesch F; Arand M; Mowbray S L; Jones T A
Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases.
Structure (London, England : 1993) 2000;8(2):111-22.
1999: Steinberg P; Fischer T; Kiulies S; Biefang K; Platt K L; Oesch F; Böttger T; Bulitta C; Kempf P; Hengstler J
Drug metabolizing capacity of cryopreserved human, rat, and mouse liver parenchymal cells in suspension.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(12):1415-22.
1999: Hengstler J G; Van der Burg B; Steinberg P; Oesch F
Interspecies differences in cancer susceptibility and toxicity.
Drug metabolism reviews 1999;31(4):917-70.
1999: Arand M; Hemmer H; Dürk H; Baratti J; Archelas A; Furstoss R; Oesch F
Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase.
The Biochemical journal 1999;344 Pt 1():273-80.
1999: Hengstler J G; Lange J; Kett A; Dornhöfer N; Meinert R; Arand M; Knapstein P G; Becker R; Oesch F; Tanner B
Contribution of c-erbB-2 and topoisomerase IIalpha to chemoresistance in ovarian cancer.
Cancer research 1999;59(13):3206-14.
1999: Steinberg P; Klingelhöffer A; Schäfer A; Wüst G; Weisse G; Oesch F; Eigenbrodt E
Expression of pyruvate kinase M2 in preneoplastic hepatic foci of N-nitrosomorpholine-treated rats.
Virchows Archiv : an international journal of pathology 1999;434(3):213-20.
1999: Schleger C; Becker R; Oesch F; Steinberg P
The human p53 gene mutated at position 249 per se is not sufficient to immortalize human liver cells.
Hepatology (Baltimore, Md.) 1999;29(3):834-8.
1999: Schlink K; Janssen K; Nitzsche S; Gebhard S; Hengstler J G; Klein S; Oesch F
Activity of O6-methylguanine DNA methyltransferase in mononuclear blood cells of formaldehyde-exposed medical students.
Archives of toxicology 1999;73(1):15-21.
1999: Wieser R J; Faust D; Dietrich C; Oesch F
p16INK4 mediates contact-inhibition of growth.
Oncogene 1999;18(1):277-81.
1999: Arand M; Müller F; Mecky A; Hinz W; Urban P; Pompon D; Kellner R; Oesch F
Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate.
The Biochemical journal 1999;337 ( Pt 1)():37-43.
1998: Seidel A; Friedberg T; Löllmann B; Schwierzok A; Funk M; Frank H; Holler R; Oesch F; Glatt H
Detoxification of optically active bay- and fjord-region polycyclic aromatic hydrocarbon dihydrodiol epoxides by human glutathione transferase P1-1 expressed in Chinese hamster V79 cells.
Carcinogenesis 1998;19(11):1975-81.
1998: Hengstler J G; Kett A; Arand M; Oesch-Bartlomowicz B; Oesch F; Pilch H; Tanner B
Glutathione S-transferase T1 and M1 gene defects in ovarian carcinoma.
Cancer letters 1998;130(1-2):43-8.
1998: Oesch-Bartlomowicz B; Padma P R; Becker R; Richter B; Hengstler J G; Freeman J E; Wolf C R; Oesch F
Differential modulation of CYP2E1 activity by cAMP-dependent protein kinase upon Ser129 replacement.
Experimental cell research 1998;242(1):294-302.
1998: Hengstler J G; Böttger T; Tanner B; Dietrich B; Henrich M; Knapstein P G; Junginger T; Oesch F
Resistance factors in colon cancer tissue and the adjacent normal colon tissue: glutathione S-transferases alpha and pi, glutathione and aldehyde dehydrogenase.
Cancer letters 1998;128(1):105-12.
1998: Tanner B; Hengstler J G; Luch A; Meinert R; Kreutz E; Arand M; Wilkens C; Hofmann M; Oesch F; Knapstein P G; Becker R
C-myc mRNA expression in epithelial ovarian carcinomas in relation to estrogen receptor status, metastatic spread, survival time, FIGO stage, and histologic grade and type.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1998;17(1):66-74.
1998: Hengstler J G; Arand M; Herrero M E; Oesch F
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;154():47-85.
1997: Dietrich C; Wallenfang K; Oesch F; Wieser R
Differences in the mechanisms of growth control in contact-inhibited and serum-deprived human fibroblasts.
Oncogene 1997;15(22):2743-7.
1997: Gemechu-Hatewu M; Platt K L; Oesch F; Hacker H J; Bannasch P; Steinberg P
Metabolic activation of aflatoxin B1 to aflatoxin B1-8,9-epoxide in woodchucks undergoing chronic active hepatitis.
International journal of cancer. Journal international du cancer 1997;73(4):587-91.
1997: Hengstler J G; Bockisch A; Fuchs J; Grimm W; Zapf A O; Lade K; Meinert R; Oesch-Bartlomowicz B; Tanner B; Oesch F
Increase in DNA single-strand break rejoining by continuous exposure of human mononuclear blood cells to radioiodine ((131)I) in vitro.
International journal of radiation biology 1997;72(5):607-13.
1997: Schleger C; Heck R; Niketeghad F; Schirmacher P; Radaeva S; Oesch F; Dienes H P; Bannasch P; Steinberg P
Establishment and characterization of a nontumorigenic cell line derived from a human hepatocellular adenoma expressing hepatocyte-specific markers.
Experimental cell research 1997;236(2):418-26.
1997: Tanner B; Hengstler J G; Laubscher S; Meinert R; Oesch F; Weikel W; Knapstein P G; Becker R
mdm 2 mRNA expression is associated with survival in ovarian cancer.
International journal of cancer. Journal international du cancer 1997;74(4):438-42.
1997: Holler R; Arand M; Mecky A; Oesch F; Friedberg T;
The membrane anchor of microsomal epoxide hydrolase from human, rat, and rabbit displays an unexpected membrane topology.
Biochemical and biophysical research communications 1997;236(3):754-9.
1997: Müller F; Arand M; Frank H; Seidel A; Hinz W; Winkler L; Hänel K; Blée E; Beetham J K; Hammock B D; Oesch F
Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates.
European journal of biochemistry / FEBS 1997;245(2):490-6.
1997: Dietrich C; Wallenfang K; Oesch F; Wieser R
Translocation of cdk2 to the nucleus during G1-phase in PDGF-stimulated human fibroblasts.
Experimental cell research 1997;232(1):72-8.
1997: Tanner B; Hengstler J G; Dietrich B; Henrich M; Steinberg P; Weikel W; Meinert R; Kaina B; Oesch F; Knapstein P G
Glutathione, glutathione S-transferase alpha and pi, and aldehyde dehydrogenase content in relationship to drug resistance in ovarian cancer.
Gynecologic oncology 1997;65(1):54-62.
1997: Zhang N; Siegel K; Odenthal M; Becker R; Oesch F; Dienes H P; Schirmacher P; Steinberg P
The role of insulin-like growth factor II in the malignant transformation of rat liver oval cells.
Hepatology (Baltimore, Md.) 1997;25(4):900-5.
1997: Hengstler J G; Hengst A; Fuchs J; Tanner B; Pohl J; Oesch F
Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1.
Mutation research 1997;373(2):215-23.
1997: Herrero M E; Arand M; Hengstler J G; Oesch F
Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide- but not from ethylene oxide-induced DNA strand breaks.
Environmental and molecular mutagenesis 1997;30(4):429-39.
1997: Padma P R; Oesch-Bartlomowicz B; Hengstler J G; Oesch F
Control of the mutagenicity of arylamines by protein kinases and phosphatases: II. Lack of response of rat liver N-acetyl transferases to phosphorylation modulators.
Archives of toxicology 1997;71(10):655-9.
1997: Oesch-Bartlomowicz B; Arens H J; Richter B; Hengstler J G; Oesch F
Control of the mutagenicity of aromatic amines by protein kinases and phosphatases. I. The protein phosphatase inhibitors okadaic acid and ortho-vanadate drastically reduce the mutagenicity of aromatic amines.
Archives of toxicology 1997;71(10):601-11.
1997: Hengstler J G; Fuchs J; Tanner B; Oesch-Bartlomowicz B; Hölz C; Oesch F
Analysis of DNA single-strand breaks in human venous blood: a technique which does not require isolation of white blood cells.
Environmental and molecular mutagenesis 1997;29(1):58-62.
1996: Becker R; Lüthgens B; Oesch F; Dienes H P; Steinberg P
Ha-rasVal12 but not p53Ser247 leads to a significant neoplastic transformation rate of the putative rat liver stem cells (oval cell).
Carcinogenesis 1996;17(12):2635-40.
1996: Fuchs J; Hengstler J G; Hummrich F; Oesch F
Transient increase in DNA strand breaks in car refinishing spray painters.
Scandinavian journal of work, environment & health 1996;22(6):438-43.
1996: Friedberg T; Holler R; Löllmann B; Arand M; Oesch F
The catalytic activity of the endoplasmic reticulum-resident protein microsomal epoxide hydrolase towards carcinogens is retained on inversion of its membrane topology.
The Biochemical journal 1996;319 ( Pt 1)():131-6.
1996: Dietrich C; Plaumann T; Oesch F; Wieser R
Subcellular distribution of ras in human and murine fibroblasts.
Biochemical and biophysical research communications 1996;226(1):172-5.
1996: Tanner B; Kreutz E; Weikel W; Meinert R; Oesch F; Knapstein P G; Becker R
Prognostic significance of c-erB-2 mRNA in ovarian carcinoma.
Gynecologic oncology 1996;62(2):268-77.
1996: Oesch F; Arand M; Benedetti M S; Castelli M G; Dostert P
Inducing properties of rifampicin and rifabutin for selected enzyme activities of the cytochrome P-450 and UDP-glucuronosyltransferase superfamilies in female rat liver.
The Journal of antimicrobial chemotherapy 1996;37(6):1111-9.
1996: Arand M; Mühlbauer R; Hengstler J; Jäger E; Fuchs J; Winkler L; Oesch F
A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms.
Analytical biochemistry 1996;236(1):184-6.
1996: Arand M; Wagner H; Oesch F
Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
The Journal of biological chemistry 1996;271(8):4223-9.
1996: Gemechu-Hatewu M; Platt K L; Oesch F; Steinberg P
Distribution and induction of aflatoxin B1-9a-hydroxylase activity in rat liver parenchymal and non-parenchymal cells.
Archives of toxicology 1996;70(9):553-8.
1996: Friedberg T; Löllmann B; Becker R; Holler R; Arand M; Oesch F
Investigating the role of the microsomal epoxide hydrolase membrane topology and its implication for drug metabolism pathways.
Advances in experimental medicine and biology 1996;387():17-24.
1995: Honscha W; Platte H D; Oesch F; Friedberg T
Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics.
The Biochemical journal 1995;311 ( Pt 3)():975-9.
1995: Oesch F; Abdel-Latif H; Diener B
Viability, attachment efficiency, and xenobiotic metabolizing enzyme activities are well maintained in EDTA isolated rat liver parenchymal cells after hypothermic preservation for up to 3 days in University of Wisconsin solution.
In vitro cellular & developmental biology. Animal 1995;31(8):590-4.
1995: Seidel A; Oesch F; Steinberg P
Malignant transformation of the liver tumour precursor cell line OC/CDE 22 by the four stereoisomeric fjord region 3,4-dihydrodiol 1,2-epoxides of benzo[c]phenanthrene.
Carcinogenesis 1995;16(9):2111-5.
1995: Oesch F; Diener B
Cell systems for use in studies on the relationship between foreign compound metabolism and toxicity.
Pharmacology & toxicology 1995;76(5):325-7.
1995: Traiser M; Diener B; Utesch D; Oesch F
The gap junctional intercellular communication is no prerequisite for the stabilization of xenobiotic metabolizing enzyme activities in primary rat liver parenchymal cells in vitro.
In vitro cellular & developmental biology. Animal 1995;31(4):266-73.
1995: Fuchs J; Burg J; Hengstler J G; Bolm-Audorff U; Oesch F
DNA damage in mononuclear blood cells of metal workers exposed to N-nitrosodiethanolamine in synthetic cutting fluids.
Mutation research 1995;342(1-2):95-102.
1995: Fuchs J; Hengstler J G; Jung D; Hiltl G; Konietzko J; Oesch F
DNA damage in nurses handling antineoplastic agents.
Mutation research 1995;342(1-2):17-23.
1995: Diener B; Becker R; Martus H J; Traiser M; Steinberg P; Oesch F
Malignantly transformed non-parenchymal liver epithelial cells and transformed oval cells suppress the homotypical gap junctional intercellular communication of co-cultured rat liver parenchymal cells.
Carcinogenesis 1995;16(3):633-6.
1995: Funk M; Gath I; Seidel A; Oesch F; Platt K L
Conjugation of anti-dihydrodiol epoxides of benzo[a]pyrene, chrysene, benzo[c]phenanthrene and dibenz[a,h]anthracene with glutathione catalyzed by cytosol and by the Mu-class glutathione transferase HTP II from rat liver.
Chemico-biological interactions 1995;95(1-2):189-201.
1995: Fändrich F; Degiuli B; Vogel-Bindel U; Arand M; Oesch F
Induction of rat liver microsomal epoxide hydrolase by its endogenous substrate 16 alpha, 17 alpha-epoxyestra-1,3,5-trien-3-ol.
Xenobiotica; the fate of foreign compounds in biological systems 1995;25(3):239-44.
1995: Hengstler J G; Fuchs J; Bolm-Audorff U; Meyer S; Oesch F
Single-strand breaks in deoxyribonucleic acid in fire fighters accidentally exposed to o-nitroanisole and other chemicals.
Scandinavian journal of work, environment & health 1995;21(1):36-42.
1995: Diener B; Abdel-Latif H; Arand M; Oesch F
Xenobiotic metabolizing enzyme activities and viability are well preserved in EDTA-isolated rat liver parenchymal cells after cryopreservation.
Toxicology and applied pharmacology 1995;130(1):149-53.
1995: Beetham J K; Grant D; Arand M; Garbarino J; Kiyosue T; Pinot F; Oesch F; Belknap W R; Shinozaki K; Hammock B D
Gene evolution of epoxide hydrolases and recommended nomenclature.
DNA and cell biology 1995;14(1):61-71.
1995: Härtter S; Arand M; Oesch F; Hiemke C
Non-competitive inhibition of clomipramine N-demethylation by fluvoxamine.
Psychopharmacology 1995;117(2):149-53.
1995: Oesch F; Hengstler J G; Arand M; Fuchs J
Detection of primary DNA damage: applicability to biomonitoring of genotoxic occupational exposure and in clinical therapy.
Pharmacogenetics 1995;5 Spec No():S118-22.
1994: Friedberg T; Löllmann B; Becker R; Holler R; Oesch F
The microsomal epoxide hydrolase has a single membrane signal anchor sequence which is dispensable for the catalytic activity of this protein.
The Biochemical journal 1994;303 ( Pt 3)():967-72.
1994: Jennings G S; Heck R; Oesch F; Steinberg P
Metabolism and cytotoxicity of aflatoxin B1 in cultured rat hepatocytes and nonparenchymal cells: implications for tumorigenesis.
Toxicology and applied pharmacology 1994;129(1):86-94.
1994: Glatt H; Pauly K; Frank H; Seidel A; Oesch F; Harvey R G; Werle-Schneider G
Substance-dependent sex differences in the activation of benzylic alcohols to mutagens by hepatic sulfotransferases of the rat.
Carcinogenesis 1994;15(11):2605-11.
1994: Luch A; Glatt H; Platt K L; Oesch F; Seidel A
Synthesis and mutagenicity of the diastereomeric fjord-region 11,12-dihydrodiol 13,14-epoxides of dibenzo[a,l]pyrene.
Carcinogenesis 1994;15(11):2507-16.
1994: Oesch F; Oesch-Bartlomowicz B; Arens J; Fähndrich F; Vogel E; Friedberg T; Glatt H
Mechanism-based predictions of interactions.
Environmental health perspectives 1994;102 Suppl 9():5-9.
1994: Steinberg P; Steinbrecher R; Radaeva S; Schirmacher P; Dienes H P; Oesch F; Bannasch P
Oval cell lines OC/CDE 6 and OC/CDE 22 give rise to cholangio-cellular and undifferentiated carcinomas after transformation.
Laboratory investigation; a journal of technical methods and pathology 1994;71(5):700-9.
1994: Thomas H; Strolin Benedetti M; Dostert P; Oesch F
The effect of indobufen on the activities of selected rat liver phase I and phase II drug metabolizing enzymes, peroxisomal beta-oxidation and hepatic glutathione status.
The Journal of pharmacy and pharmacology 1994;46(10):833-7.
1994: Glatt H; Seidel A; Oesch F; Gumbsch A
Fjord-region diol-epoxides of benzo[c]chrysene are potent inducers of micronuclei in murine bone marrow.
Mutation research 1994;309(1):37-43.
1994: Oesch F; Hengstler J G; Fuchs J
Cigarette smoking protects mononuclear blood cells of carcinogen exposed workers from additional work exposure-induced DNA single strand breaks.
Mutation research 1994;321(3):175-85.
1994: Dunkelberg H; Fuchs J; Hengstler J G; Klein E; Oesch F; Strüder K
Genotoxic effects of the herbicides alachlor, atrazine, pendimethaline, and simazine in mammalian cells.
Bulletin of environmental contamination and toxicology 1994;52(4):498-504.
1994: Friedberg T; Becker R; Oesch F; Glatt H
Studies on the importance of microsomal epoxide hydrolase in the detoxification of arene oxides using the heterologous expression of the enzyme in mammalian cells.
Carcinogenesis 1994;15(2):171-5.
1994: Arand M; Grant D F; Beetham J K; Friedberg T; Oesch F; Hammock B D
Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins. Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis.
FEBS letters 1994;338(3):251-6.
1994: Post K; Seidel A; Platt K L; Oesch F; Klein J
Regiospecific reduction of polycyclic aromatic quinones by rabbit liver dihydrodiol dehydrogenases.
Chemico-biological interactions 1994;90(2):157-68.
1994: Diener B; Beer N; Dürk H; Traiser M; Utesch D; Wieser R J; Oesch F
Gap junctional intercellular communication of cultured rat liver parenchymal cells is stabilized by epithelial cells and their isolated plasma membranes.
Experientia 1994;50(2):124-6.
1994: Funk M; Gath I; Seidel A; Platt K L; Oesch F; Zeller H D
Different enzyme kinetics during the glutathione conjugation of the four stereoisomers of the fjord-region diolepoxides of benzo[c]phenanthrene by the mu-class rat liver glutathione S-transferase HTP II.
Biochemical pharmacology 1994;47(3):505-14.
1994: Hammock B D; Pinot F; Beetham J K; Grant D F; Arand M E; Oesch F
Isolation of a putative hydroxyacyl enzyme intermediate of an epoxide hydrolase.
Biochemical and biophysical research communications 1994;198(3):850-6.
1994: Steinberg P; Steinbrecher R; Schrenk D; Munzel P; Bruck M; Gschaidmaier H; Oesch F; Bock K W
Drug-metabolizing enzyme activities in freshly isolated oval cells and in an established oval cell line from carcinogen-fed rats.
Cell biology and toxicology 1994;10(1):59-65.
1994: Steinberg P; Weisse G; Eigenbrodt E; Oesch F
Expression of L- and M2-pyruvate kinases in proliferating oval cells and cholangiocellular lesions developing in the livers of rats fed a methyl-deficient diet.
Carcinogenesis 1994;15(1):125-7.
1994: Lorenz J; Friedberg T; Paulus R; Oesch F; Ferlinz R
Oncogene overexpression in non-small-cell lung cancer tissue: prevalence and clinicopathological significance.
The Clinical investigator 1994;72(2):156-63.
1994: Hengstler J G; Fuchs J; Gebhard S; Oesch F
Glycolaldehyde causes DNA-protein crosslinks: a new aspect of ethylene oxide genotoxicity.
Mutation research 1994;304(2):229-34.
1994: Oesch F; Diener B
Rational species extrapolation of toxic effects.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1994;16():161-8.
1994: Oesch F; Weiss C M; Klein S
Use of oligonucleotides containing ethenoadenine to study the repair of this DNA lesion. Determination of individual and collective repair activities.
Archives of toxicology 1994;68(6):358-63.
1994: Fuchs J; Wullenweber U; Hengstler J G; Bienfait H G; Hiltl G; Oesch F
Genotoxic risk for humans due to work place exposure to ethylene oxide: remarkable individual differences in susceptibility.
Archives of toxicology 1994;68(6):343-8.
1993: Krämer A; Pudil J; Frank H; Oesch F; Glatt H
Some substrates and inhibitors of cytosolic epoxide hydrolase induce sister-chromatid exchanges in mammalian cells, but do not induce gene mutations in Salmonella typhimurium and V79 cells.
Mutation research 1993;290(2):165-74.
1993: Knehr M; Thomas H; Arand M; Gebel T; Zeller H D; Oesch F
Isolation and characterization of a cDNA encoding rat liver cytosolic epoxide hydrolase and its functional expression in Escherichia coli.
The Journal of biological chemistry 1993;268(23):17623-7.
1993: Fuchs J; Mlcoch J; Platt K L; Oesch F
Characterization of highly polar bis-dihydrodiol epoxide--DNA adducts formed after metabolic activation of dibenz[a,h]anthracene.
Carcinogenesis 1993;14(5):863-7.
1993: Fuchs J; Mlcoch J; Oesch F; Platt K L
Characterization of highly polar DNA adducts derived from dibenz[A,H]anthracene (DBA), 3,4-dihydroxy-3,4-dihydro-DBA, and 3,4,10,11-tetrahydroxy-3,4,10,11-tetrahydro-DBA.
Toxicology and industrial health 1993;9(3):503-9.
1993: Diener B; Utesch D; Beer N; Dürk H; Oesch F
A method for the cryopreservation of liver parenchymal cells for studies of xenobiotics.
Cryobiology 1993;30(2):116-27.
1993: Mlcoch J; Fuchs J; Oesch F; Platt K L
Characterization of DNA adducts at the bay region of dibenz[a,h]anthracene formed in vitro.
Carcinogenesis 1993;14(3):469-73.
1993: Utesch D; Traiser M; Gath I; Dorresteijn A W; Maier P; Oesch F
Effects of sodium butyrate on DNA content, glutathione S-transferase activities, cell morphology and growth characteristics of rat liver nonparenchymal epithelial cells in vitro.
Carcinogenesis 1993;14(3):457-62.
1993: Pack R; Heck R; Dienes H P; Oesch F; Steinberg P
Isolation, biochemical characterization, long-term culture, and phenotype modulation of oval cells from carcinogen-fed rats.
Experimental cell research 1993;204(2):198-209.
1993: Glatt H; Wameling C; Elsberg S; Thomas H; Marquardt H; Hewer A; Phillips D H; Oesch F; Seidel A
Genotoxicity characteristics of reverse diol-epoxides of chrysene.
Carcinogenesis 1993;14(1):11-9.
1993: Monnerjahn S; Seidel A; Steinberg P; Oesch F; Hinz M; Stezowsky J J; Hewer A; Phillips D H; Glatt H R
Formation of DNA adducts from 1-hydroxymethylpyrene in liver cells in vivo and in vitro.
IARC scientific publications 1993;(124):189-93.
1992: Utesch D; Arand M; Thomas H; Petzinger E; Oesch F
Xenobiotic-metabolizing enzyme activities in hybrid cell lines established by fusion of primary rat liver parenchymal cells with hepatoma cells.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(12):1451-7.
1992: Oesch F; Oesch-Bartlomowicz B; Arens H J; Friedberg T; Utesch D; Glatt H R; Platt K L
Molecular and cellular basis for adequate metabolic design of genotoxicity studies.
Toxicology letters 1992;64-65 Spec No():643-9.
1992: Oesch F; Wagner H; Platt K L; Arand M
Improved sample preparation for the testosterone hydroxylation assay using disposable extraction columns.
Journal of chromatography 1992;582(1-2):232-5.
1992: Friedberg T; Grassow M A; Bartlomowicz-Oesch B; Siegert P; Arand M; Adesnik M; Oesch F
Sequence of a novel cytochrome CYP2B cDNA coding for a protein which is expressed in a sebaceous gland, but not in the liver.
The Biochemical journal 1992;287 ( Pt 3)():775-83.
1992: Tanner B; Friedberg T; Mitze M; Beck T; Oesch F; Knapstein P G
C-erbB-2-oncogene expression in breast carcinoma: analysis by S1 nuclease protection assay and immunohistochemistry in relation to clinical parameters.
Gynecologic oncology 1992;47(2):228-33.
1992: Arand M; Friedberg T; Oesch F
Colorimetric quantitation of trace amounts of sodium lauryl sulfate in the presence of nucleic acids and proteins.
Analytical biochemistry 1992;207(1):73-5.
1992: Steinberg P; Störkel S; Oesch F; Thoenes W
Carbohydrate metabolism in human renal clear cell carcinomas.
Laboratory investigation; a journal of technical methods and pathology 1992;67(4):506-11.
1992: Hengstler J G; Fuchs J; Oesch F
DNA strand breaks and DNA cross-links in peripheral mononuclear blood cells of ovarian cancer patients during chemotherapy with cyclophosphamide/carboplatin.
Cancer research 1992;52(20):5622-6.
1992: Klein S; Oesch F
Assay for O6-alkylguanine-DNA-alkyltransferase using oligonucleotides containing O6-methylguanine in a BamHI recognition site as substrate.
Analytical biochemistry 1992;205(2):294-9.
1992: Doehmer J; Wölfel C; Dogra S; Doehmer C; Seidel A; Platt K L; Oesch F; Glatt H R
Applications of stable V79-derived cell lines expressing rat cytochromes P4501A1, 1A2, and 2B1.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(9-10):1093-9.
1992: Gebel T; Arand M; Oesch F
Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver.
FEBS letters 1992;309(1):37-40.
1992: Klein J; Post K; Seidel A; Frank H; Oesch F; Platt K L
Quinone reduction and redox cycling catalysed by purified rat liver dihydrodiol/3 alpha-hydroxysteroid dehydrogenase.
Biochemical pharmacology 1992;44(2):341-9.
1992: Utesch D; Diener B; Molitor E; Oesch F; Platt K L
Characterization of cryopreserved rat liver parenchymal cells by metabolism of diagnostic substrates and activities of related enzymes.
Biochemical pharmacology 1992;44(2):309-15.
1992: Utesch D; Oesch F
Phenol sulfotransferase activity in rat liver parenchymal cells cultured on collagen gels.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(4):614-5.
1992: Jennings G S; Oesch F; Steinberg P
In vivo formation of aflatoxin B1-DNA adducts in parenchymal and non-parenchymal cells of rat liver.
Carcinogenesis 1992;13(5):831-5.
1992: Klein J; Thomas H; Post K; Wörner W; Oesch F
Dihydrodiol dehydrogenase activities of rabbit liver are associated with hydroxysteroid dehydrogenases and aldo-keto reductases.
European journal of biochemistry / FEBS 1992;205(3):1155-62.
1992: Oesch F; Klein S
Relevance of environmental alkylating agents to repair protein O6-alkylguanine-DNA alkyltransferase: determination of individual and collective repair capacities of O6-methylguanine.
Cancer research 1992;52(7):1801-3.
1992: Utesch D; Oesch F
Dependency of the in vitro stabilization of differentiated functions in liver parenchymal cells on the type of cell line used for co-culture.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1992;28A(3 Pt 1):193-8.
1992: Oesch F; Arand M; Coughtrie M W; Burchell B; Steinberg P
The distribution of UDP-glucuronosyltransferases in rat liver parenchymal and nonparenchymal cells.
Biochemical pharmacology 1992;43(4):731-7.
1991: Arand M; Knehr M; Thomas H; Zeller H D; Oesch F
An impaired peroxisomal targeting sequence leading to an unusual bicompartmental distribution of cytosolic epoxide hydrolase.
FEBS letters 1991;294(1-2):19-22.
1991: Krämer A; Frank H; Setiabudi F; Oesch F; Glatt H
Influence of the level of cytosolic epoxide hydrolase on the induction of sister chromatid exchanges by trans-beta-ethylstyrene 7,8-oxide in human lymphocytes.
Biochemical pharmacology 1991;42(11):2147-52.
1991: Utesch D; Molitor E; Platt K L; Oesch F
Differential stabilization of cytochrome P-450 isoenzymes in primary cultures of adult rat liver parenchymal cells.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1991;27A(11):858-63.
1991: Honscha W; Oesch F; Friedberg T
Tissue-specific expression and differential inducibility of several microsomal epoxide hydrolase mRNAs which are formed by alternative splicing.
Archives of biochemistry and biophysics 1991;287(2):380-5.
1991: Glatt H; Piée A; Pauly K; Steinbrecher T; Schrode R; Oesch F; Seidel A
Fjord- and bay-region diol-epoxides investigated for stability, SOS induction in Escherichia coli, and mutagenicity in Salmonella typhimurium and mammalian cells.
Cancer research 1991;51(6):1659-67.
1991: Steinberg P; Hacker H J; Dienes H P; Oesch F; Bannasch P
Enzyme histochemical and immunohistochemical characterization of oval and parenchymal cells proliferating in livers of rats fed a choline-deficient/DL-ethionine-supplemented diet.
Carcinogenesis 1991;12(2):225-31.
1991: Oesch F; Gath I; Igarashi T; Glatt H; Oesch-Bartlomowicz B; Thomas H
Role of the well-known basic and recently discovered acidic glutathione S-transferases in the control of genotoxic metabolites.
Advances in experimental medicine and biology 1991;283():25-39.
1991: Klein J; Seidel A; Frank H; Oesch F; Platt K L
Regiospecific oxidation of polycyclic aromatic dihydrodiols by rat liver dihydrodiol dehydrogenase.
Chemico-biological interactions 1991;79(3):287-303.
1991: Arand M; Coughtrie M W; Burchell B; Oesch F; Robertson L W
Selective induction of bilirubin UDP-glucuronosyl-transferase by perfluorodecanoic acid.
Chemico-biological interactions 1991;77(1):97-105.
1991: Schlemper B; Harrison J; Garner R C; Oesch F; Steinberg P
DNA binding, adduct characterisation and metabolic activation of aflatoxin B1 catalysed by isolated rat liver parenchymal, Kupffer and endothelial cells.
Archives of toxicology 1991;65(8):633-9.
1990: Wieser R J; Schütz S; Tschank G; Thomas H; Dienes H P; Oesch F
Isolation and characterization of a 60-70-kD plasma membrane glycoprotein involved in the contact-dependent inhibition of growth.
The Journal of cell biology 1990;111(6 Pt 1):2681-92.
1990: Platt K L; Pfeiffer E; Petrovic P; Friesel H; Beermann D; Hecker E; Oesch F
Comparative tumorigenicity of picene and dibenz[a,h]anthracene in the mouse.
Carcinogenesis 1990;11(10):1721-6.
1990: Oesch-Bartlomowicz B; Vogel S; Arens H J; Oesch F
Modulation of the control of mutagenic metabolites derived from cyclophosphamide and ifosfamide by stimulation of protein kinase A.
Mutation research 1990;232(2):305-12.
1990: Klein S; Oesch F
A new assay for O6-alkylguanine-DNA-alkyltransferase to determine DNA repair capacities using lambda-phage DNA as substrate.
Carcinogenesis 1990;11(10):1771-4.
1990: Friedberg T; Siegert P; Grassow M A; Bartlomowicz B; Oesch F
Studies of the expression of the cytochrome P450IA, P450IIB, and P450IIC gene family in extrahepatic and hepatic tissues.
Environmental health perspectives 1990;88():67-70.
1990: Doehmer J; Seidel A; Oesch F; Glatt H R
Genetically engineered V79 Chinese hamster cells metabolically activate the cytostatic drugs cyclophosphamide and ifosfamide.
Environmental health perspectives 1990;88():63-5.
1990: Thomas H; Schladt L; Doehmer J; Knehr M; Oesch F
Rat and human liver cytosolic epoxide hydrolases: evidence for multiple forms at level of protein and mRNA.
Environmental health perspectives 1990;88():49-55.
1990: Glatt H; Henschler R; Phillips D H; Blake J W; Steinberg P; Seidel A; Oesch F
Sulfotransferase-mediated chlorination of 1-hydroxymethylpyrene to a mutagen capable of penetrating indicator cells.
Environmental health perspectives 1990;88():43-8.
1990: Platt K L; Schollmeier M; Frank H; Oesch F
Stereoselective metabolism of dibenz(a,h)anthracene to trans-dihydrodiols and their activation to bacterial mutagens.
Environmental health perspectives 1990;88():37-41.
1990: Wieser R J; Renauer D; Schäfer A; Heck R; Engel R; Schütz S; Oesch F
Growth control in mammalian cells by cell-cell contacts.
Environmental health perspectives 1990;88():251-3.
1990: Gerharz C D; Doehmer J; Mayer H; Oesch F; Gabbert H
Morphological, biochemical, and molecular biological characterization of a rat rhabdomyosarcoma cell line during differentiation induction in vitro.
Environmental health perspectives 1990;88():187-91.
1990: Steinberg P; Schlemper B; Molitor E; Platt K L; Seidel A; Oesch F
Rat liver endothelial and Kupffer cell-mediated mutagenicity of polycyclic aromatic hydrocarbons and aflatoxin B1.
Environmental health perspectives 1990;88():71-6.
1990: Glatt H; Gemperlein I; Setiabudi F; Platt K L; Oesch F
Expression of xenobiotic-metabolizing enzymes in propagatable cell cultures and induction of micronuclei by 13 compounds.
Mutagenesis 1990;5(3):241-9.
1990: Oesch F; Doehmer J; Friedberg T; Glatt H R; Oesch-Bartlomowicz B; Platt K L; Steinberg P; Utesch D; Thomas H
Toxicological implications of enzymatic control of reactive metabolites.
Human & experimental toxicology 1990;9(3):171-7.
1990: Friedberg T; Grassow M A; Oesch F
Selective detection of mRNA forms encoding the major phenobarbital inducible cytochromes P450 and other members of the P450IIB family by the RNAse A protection assay.
Archives of biochemistry and biophysics 1990;279(1):167-73.
1990: Dogra S; Doehmer J; Glatt H; Mölders H; Siegert P; Friedberg T; Seidel A; Oesch F
Stable expression of rat cytochrome P-450IA1 cDNA in V79 Chinese hamster cells and their use in mutagenicity testing.
Molecular pharmacology 1990;37(5):608-13.
1990: Schäfer A; Wieser R J; Romero F; Oesch F
Reduction of glutathione content by 12-O-tetradecanoylphorbol-13-acetate in confluent, but not in sparse cultures of human diploid fibroblasts.
Carcinogenesis 1990;11(4):697-9.
1990: Gabbert H E; Gerharz C D; Ramp U; Hoffmann J; Oster O; Oesch F; Doehmer J
Enhanced expression of the proto-oncogenes fos and raf in the rhabdomyosarcoma cell line BA-HAN-1C after differentiation induction with retinoic acid and N-methylformamide.
International journal of cancer. Journal international du cancer 1990;45(4):724-30.
1990: Glatt H; Utesch D; Herbst M; Oesch F
Mutagenicity experiments on L-cysteine and D-penicillamine using V79 cells as indicators and for metabolic activation.
Mutation research 1990;243(3):187-93.
1990: Klein J; Post K; Thomas H; Wörner W; Setiabudi F; Frank H; Oesch F; Platt K L
The oxidation of the highly tumorigenic benz[a]anthracene 3,4-dihydrodiol by rat liver dihydrodiol dehydrogenase.
Chemico-biological interactions 1990;76(2):211-26.
1990: Oesch F; Doehmer J; Friedberg T; Glatt H; Oesch-Bartlomowicz B; Platt K L; Steinberg P; Utesch D; Thomas H
Control of ultimate mutagenic species by diverse enzymes.
Progress in clinical and biological research 1990;340B():49-65.
1989: Thomas H; Schladt L; Knehr M; Oesch F
Effect of diabetes and starvation on the activity of rat liver epoxide hydrolases, glutathione S-transferases and peroxisomal beta-oxidation.
Biochemical pharmacology 1989;38(23):4291-7.
1989: Steinberg P; Schramm H; Schladt L; Robertson L W; Thomas H; Oesch F
The distribution, induction and isoenzyme profile of glutathione S-transferase and glutathione peroxidase in isolated rat liver parenchymal, Kupffer and endothelial cells.
The Biochemical journal 1989;264(3):737-44.
1989: Glatt H; Padykula R; Berchtold G A; Ludewig G; Platt K L; Klein J; Oesch F
Multiple activation pathways of benzene leading to products with varying genotoxic characteristics.
Environmental health perspectives 1989;82():81-9.
1989: Thomas H; Schladt L; Knehr M; Post K; Oesch F; Boiteux-Antoine A F; Fournel-Gigleux S; Magdalou J; Siest G
Effect of hypolipidemic compounds on lauric acid hydroxylation and phase II enzymes.
Biochemical pharmacology 1989;38(12):1963-9.
1989: Bartlomowicz B; Friedberg T; Utesch D; Molitor E; Platt K; Oesch F
Regio- and stereoselective regulation of monooxygenase activities by isoenzyme-selective phosphorylation of cytochrome P450.
Biochemical and biophysical research communications 1989;160(1):46-52.
1989: Oesch F; Waxman D J; Morrissey J J; Honscha W; Kissel W; Friedberg T
Antibodies targeted against hypervariable and constant regions of cytochromes P450IIB1 and P450IIB2.
Archives of biochemistry and biophysics 1989;270(1):23-32.
1989: Püttmann M; Mannschreck A; Oesch F; Robertson L
Chiral effects in the induction of drug-metabolizing enzymes using synthetic atropisomers of polychlorinated biphenyls (PCBs).
Biochemical pharmacology 1989;38(8):1345-52.
1989: Renauer D; Oesch F; Heck R; Wieser R
Identification of plasma membrane glycoproteins involved in the contact-dependent inhibition of growth of diploid human fibroblasts.
Experimental cell research 1989;180(2):504-14.
1989: Oesch F; Wolf C R
Properties of the microsomal and cytosolic glutathione transferases involved in hexachloro-1:3-butadiene conjugation.
Biochemical pharmacology 1989;38(2):353-9.
1989: Bartlomowicz B; Waxman D J; Utesch D; Oesch F; Friedberg T
Phosphorylation of carcinogen metabolizing enzymes: regulation of the phosphorylation status of the major phenobarbital inducible cytochromes P-450 in hepatocytes.
Carcinogenesis 1989;10(1):225-8.
1989: Platt K L; Molitor E; Döhmer J; Dogra S; Oesch F
Genetically engineered V79 Chinese hamster cell expression of purified cytochrome P-450IIB1 monooxygenase activity.
Journal of biochemical toxicology 1989;4(1):1-6.
1989: Seibert B; Oesch F; Steinberg P
Distribution and induction of cytochrome P-450 and two cytochrome P-450-dependent monooxygenase activities in rat liver parenchymal cell subpopulations separated by centrifugal elutriation.
Archives of toxicology 1989;63(1):18-22.
1989: Schramm H; Friedberg T; Robertson L W; Oesch F; Kissel W
Perfluorodecanoic acid decreases the enzyme activity and the amount of glutathione S-transferases proteins and mRNAs in vivo.
Chemico-biological interactions 1989;70(1-2):127-43.
1989: Friedberg T; Timms C; Kissel W; Oesch F
Evidence for several hepatic proteins related to microsomal epoxide hydrolase.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1989;13():145-52.
1988: Oesch F
Antimutagenesis by shift in monooxygenase isoenzymes and induction of epoxide hydrolase.
Mutation research 1988;202(2):335-42.
1988: Wieser R J; Janik-Schmitt B; Renauer D; Schäfer A; Heck R; Oesch F
Contact-dependent inhibition of growth of normal diploid human fibroblasts by plasma membrane glycoproteins.
Biochimie 1988;70(11):1661-71.
1988: Schladt L; Thomas H; Hartmann R; Oesch F
Human liver cytosolic epoxide hydrolases.
European journal of biochemistry / FEBS 1988;176(3):715-23.
1988: Steinberg P; Schladt L; Dienes H P; Timms C; Oesch F
Microsomal and cytosolic epoxide hydrolases, the peroxisomal fatty acid beta-oxidation system and catalase. Activities, distribution and induction in rat liver parenchymal and non-parenchymal cells.
European journal of biochemistry / FEBS 1988;176(1):39-45.
1988: Schladt L; Hartmann R; Wörner W; Thomas H; Oesch F
Purification and characterization of rat-liver cytosolic epoxide hydrolase.
European journal of biochemistry / FEBS 1988;176(1):31-7.
1988: Amelizad Z; Narbonne J F; Wolf C R; Robertson L W; Oesch F
Effect of nutritional imbalances on cytochrome P-450 isozymes in rat liver.
Biochemical pharmacology 1988;37(17):3245-9.
1988: Magdalou J; Totis M; Boiteux-Antoine A F; Fournel-Gigleux S; Siest G; Schladt L; Oesch F
Effect of 1-benzylimidazole on cytochromes P-450 induction and on the activities of epoxide hydrolases and UDP-glucuronosyltransferases in rat liver.
Biochemical pharmacology 1988;37(17):3297-304.
1988: Doehmer J; Dogra S; Friedberg T; Monier S; Adesnik M; Glatt H; Oesch F
Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):5769-73.
1988: Oesch F; Schäfer A; Wieser R J
12-O-tetradecanoylphorbol-13-acetate releases human diploid fibroblasts from contact-dependent inhibition of growth.
Carcinogenesis 1988;9(7):1319-22.
1988: Wieser R J; Oesch F
Contact-dependent regulation of growth of diploid human fibroblasts is dependent upon the presence of terminal galactose residues on plasma membrane glycoproteins.
Experimental cell research 1988;176(1):80-6.
1988: Oesch F; Glatt H; Utesch D
Metabolic perspectives on in vitro toxicity tests.
Xenobiotica; the fate of foreign compounds in biological systems 1988;18 Suppl 1():35-44.
1988: Platt K L; Petrovic P; Seidel A; Beermann D; Oesch F
Microsomal metabolism of picene.
Chemico-biological interactions 1988;66(3-4):157-75.
1988: Dogra S; Filser J G; Cojocel C; Greim H; Regel U; Oesch F; Robertson L W
Long-term effects of commercial and congeneric polychlorinated biphenyls on ethane production and malondialdehyde levels, indicators of in vivo lipid peroxidation.
Archives of toxicology 1988;62(5):369-74.
1988: Oesch F; Hartmann R; Timms C; Strolin-Benedetti M; Dostert P; Wörner W; Schladt L
Time-dependence and differential induction of rat and guinea pig peroxisomal beta-oxidation, palmitoyl-CoA hydrolase, cytosolic and microsomal epoxide hydrolase after treatment with hypolipidemic drugs.
Journal of cancer research and clinical oncology 1988;114(4):341-6.
1987: Rauch P; Püttmann M; Oesch F; Okamoto Y; Robertson L W
Differential induction of cytochrome P-450 by the enantiomers of trans-stilbene oxide.
Biochemical pharmacology 1987;36(24):4355-9.
1987: Glatt H; Seidel A; Ribeiro O; Kirkby C; Hirom P; Oesch F
Metabolic activation to a mutagen of 3-hydroxy-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene, a secondary metabolite of benzo[a]pyrene.
Carcinogenesis 1987;8(11):1621-7.
1987: Steinberg P; Lafranconi W M; Wolf C R; Waxman D J; Oesch F; Friedberg T
Xenobiotic metabolizing enzymes are not restricted to parenchymal cells in rat liver.
Molecular pharmacology 1987;32(4):463-70.
1987: Wieser R J; Oesch F
Plasma membrane glycoproteins covalently bound to silica beads as a model for molecular studies of cell-cell interactions in culture.
Journal of biochemical and biophysical methods 1987;15(1):13-21.
1987: Amelizad Z; Narbonne J F; Borin C; Robertson L W; Periquet A; Oesch F
Effect of unbalanced diets on incorporation of delta-aminolevulinic acid into cytochrome P-450.
FEBS letters 1987;220(1):231-5.
1987: Arand M; Robertson L W; Oesch F
A fluorometric assay for quantitating phenol sulfotransferase activities in homogenates of cells and tissues.
Analytical biochemistry 1987;163(2):546-51.
1987: Oesch F; Janik-Schmitt B; Ludewig G; Glatt H; Wieser R J
Glutaraldehyde-fixed transformed and non-transformed cells induce contact-dependent inhibition of growth in non-transformed C3H/10T1/2 mouse fibroblasts, but not in 3-methylcholanthrene-transformed cells.
European journal of cell biology 1987;43(3):403-7.
1987: Janik-Schmitt B; Oesch F; Wieser R J
Immobilized glycolipids from human diploid fibroblasts inhibit DNA synthesis of cultured human fibroblasts.
Experimental cell research 1987;169(1):15-24.
1987: Turchi G; Carluccio M A; Oesch F; Gemperlein I; Glatt H R
Characterization of an epithelial, nearly diploid liver cell strain, from Chinese hamster, able to activate promutagens.
Mutagenesis 1987;2(2):127-35.
1987: Schladt L; Hartmann R; Timms C; Strolin-Benedetti M; Dostert P; Wörner W; Oesch F
Concomitant induction of cytosolic but not microsomal epoxide hydrolase with peroxisomal beta-oxidation by various hypolipidemic compounds.
Biochemical pharmacology 1987;36(3):345-51.
1987: Glatt H; Gemperlein I; Turchi G; Heinritz H; Doehmer J; Oesch F
Search for cell culture systems with diverse xenobiotic-metabolizing activities and their use in toxicological studies.
Molecular toxicology 1987;1(4):313-34.
1986: Schladt L; Wörner W; Setiabudi F; Oesch F
Distribution and inducibility of cytosolic epoxide hydrolase in male Sprague-Dawley rats.
Biochemical pharmacology 1986;35(19):3309-16.
1986: Amelizad Z; Narbonne J F; Daubeze M; Bonnamour D; Oesch F
Monooxygenase activity of systems reconstituted with fractions from rats fed standard and low protein diets.
Biochemical pharmacology 1986;35(18):3169-71.
1986: Glatt H; Oesch F; Neumann H G
V79 Chinese hamster cells deacetylate trans-N-acetoxy-4-acetylaminostilbene and trans-N-hydroxy-4-acetylaminostilbene to mutagenic and cytotoxic metabolites.
Cell biology and toxicology 1986;2(2):213-21.
1986: Oesch F; Schladt L; Hartmann R; Timms C; Wörner W
Rat cytosolic epoxide hydrolase.
Advances in experimental medicine and biology 1986;197():195-201.
1986: Glatt H; Shtelzer S; Sheradsky T; Blum J; Oesch F
Mutagenicity of N-substituted phenanthrene 9,10-imines in Salmonella typhimurium and Chinese hamster V79 cells.
Environmental mutagenesis 1986;8(6):829-37.
1985: Renauer D; Oesch F; Kinkel J; Unger K K; Wieser R J
Fractionation of membrane proteins on immobilized lectins by high-performance liquid affinity chromatography.
Analytical biochemistry 1985;151(2):424-7.
1985: Wieser R J; Heck R; Oesch F
Involvement of plasma membrane glycoproteins in the contact-dependent inhibition of growth of human fibroblasts.
Experimental cell research 1985;158(2):493-9.
1985: Glatt H; Ludewig G; Platt K L; Waechter F; Yona I; Ben-Shoshan S; Jerushalmy P; Blum J; Oesch F
Arene imines, a new class of exceptionally potent mutagens in bacterial and mammalian cells.
Cancer research 1985;45(6):2600-7.

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