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Masatsugu Oh-hora

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Paula Nunes; Masatsugu Oh-hora; Jean-Marc Waldburger; Vanessa Bochet; Daniela Cornut; Udo Hasler; Nicolas Demaurex
STIM1 juxtaposes ER to phagosomes, generating Ca²⁺ hotspots that boost phagocytosis.
Kwong Tai Cheng; Stefan Feske; Xibao Liu; Masatsugu Oh-hora; William D Swaim; Hongen Yin; Ilias Alevizos; Indu S Ambudkar
STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjogren's syndrome.
Tianyu Li; Masatsugu Oh-hora; Zhu-Shan Zhang; Jarrett Burch; Jin-Dong Ding; Elizabeth A Finch; Victoria Graham; Paul Rosenberg
STIM1-Ca(2+) signaling is required for the hypertrophic growth of skeletal muscle in mice.

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2012: Paula Nunes; Masatsugu Oh-hora; Jean-Marc Waldburger; Vanessa Bochet; Daniela Cornut; Udo Hasler; Nicolas Demaurex
STIM1 juxtaposes ER to phagosomes, generating Ca²⁺ hotspots that boost phagocytosis.
Current biology : CB 2012;22(21):1990-7.
2012: Kwong Tai Cheng; Stefan Feske; Xibao Liu; Masatsugu Oh-hora; William D Swaim; Hongen Yin; Ilias Alevizos; Indu S Ambudkar
STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjogren's syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(36):14544-9.
2012: Tianyu Li; Masatsugu Oh-hora; Zhu-Shan Zhang; Jarrett Burch; Jin-Dong Ding; Elizabeth A Finch; Victoria Graham; Paul Rosenberg
STIM1-Ca(2+) signaling is required for the hypertrophic growth of skeletal muscle in mice.
Molecular and cellular biology 2012;32(15):3009-17.
2011: Tomoki Nakashima; Masatsugu Oh-hora; Josef M Penninger; Lynda F Bonewald; Jian Q Feng; Takanobu Fukunaga; Mikihito Hayashi; Tatsuhiko Kodama; Kosaku Kurata; Erwin F Wagner; Anton Wutz; Hiroshi Takayanagi
Evidence for osteocyte regulation of bone homeostasis through RANKL expression.
Nature medicine 2011;17(10):1231-4.
2011: William Zeiger; Mitchel L Villereal; Daisuke Ito; Masatsugu Oh-hora; Carol Swetlik; Gopal Thinakaran
Stanniocalcin 2 is a negative modulator of store-operated calcium entry.
Molecular and cellular biology 2011;31(18):3710-22.
2010: Christie-Ann McCarl; Sara Khalil; Jian Ma; Masatsugu Oh-hora; Megumi Yamashita; Jens Roether; Takumi Kawasaki; Amit Jairaman; Yoshiteru Sasaki; Murali Prakriya; Stefan Feske
Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(10):5845-58.
2010: Jean-Paul Decuypere; Giovanni Monaco; Santeri Kiviluoto; Masatsugu Oh-hora; Tomas Luyten; Humbert De Smedt; Jan B Parys; Ludwig Missiaen; Geert Bultynck
STIM1, but not STIM2, is required for proper agonist-induced Ca2+ signaling.
Cell calcium 2010;48(2-3):161-7.
2010: Kazuo Okamoto; Yoshiko Iwai; Masatsugu Oh-hora; Masahiro Yamamoto; Tomohiro Morio; Kazuhiro Aoki; Keiichi Ohya; Anton M Jetten; Shizuo Akira; Tatsushi Muta; Hiroshi Takayanagi
IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors.
Nature 2010;464(7293):1381-5.
2010: Yubin Zhou; Sweta Ramachandran; Masatsugu Oh-hora; Anjana Rao; Patrick G Hogan
Pore architecture of the ORAI1 store-operated calcium channel.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(11):4896-901.
2009: Masatsugu Oh-hora
Calcium signaling in the development and function of T-lineage cells.
Immunological reviews 2009;231(1):210-24.
2009: Masatsugu Oh-hora; Anjana Rao
The calcium/NFAT pathway: role in development and function of regulatory T cells.
Microbes and infection / Institut Pasteur 2009;11(5):612-9.
2009: Wolfgang Bergmeier; Masatsugu Oh-hora; Christie-Ann McCarl; R Claire Roden; Paul F Bray; Stefan Feske
R93W mutation in Orai1 causes impaired calcium influx in platelets.
Blood 2009;113(3):675-8.
2008: Yousang Gwack; Sonal Srikanth; Masatsugu Oh-hora; Patrick G Hogan; Edward D Lamperti; Megumi Yamashita; Curtis Gelinas; Daniel S Neems; Yoshiteru Sasaki; Stefan Feske; Murali Prakriya; Klaus Rajewsky; Anjana Rao
Hair loss and defective T- and B-cell function in mice lacking ORAI1.
Molecular and cellular biology 2008;28(17):5209-22.
2008: Valarie A Barr; Kelsie M Bernot; Sonal Srikanth; Yousang Gwack; Lakshmi Balagopalan; Carole K Regan; Daniel J Helman; Connie L Sommers; Masatsugu Oh-hora; Anjana Rao; Lawrence E Samelson
Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps.
Molecular biology of the cell 2008;19(7):2802-17.
2008: Masatsugu Oh-hora; Anjana Rao
Calcium signaling in lymphocytes.
Current opinion in immunology 2008;20(3):250-8.
2008: Masatsugu Oh-hora; Megumi Yamashita; Patrick G Hogan; Sonia Sharma; Ed Lamperti; Woo Chung; Murali Prakriya; Stefan Feske; Anjana Rao
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance.
Nature immunology 2008;9(4):432-43.
2007: Yousang Gwack; Sonal Srikanth; Stefan Feske; Fernando Cruz-Guilloty; Masatsugu Oh-hora; Daniel S Neems; Patrick G Hogan; Anjana Rao
Biochemical and functional characterization of Orai proteins.
The Journal of biological chemistry 2007;282(22):16232-43.
2007: Yuka Okada; Yuko Ueshin; Ayako Isotani; Tomoko Saito-Fujita; Hisako Nakashima; Kazushi Kimura; Akira Mizoguchi; Masatsugu Oh-hora; Yoshiko Mori; Masato Ogata; Robert Glen Oshima; Masaru Okabe; Masahito Ikawa
Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer.
Nature biotechnology 2007;25(2):233-7.
2004: Yuichi Aiba; Masatsugu Oh-hora; Shigeki Kiyonaka; Yayoi Kimura; Atsushi Hijikata; Yasuo Mori; Tomohiro Kurosaki
Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(47):16612-7.
2003: Masatsugu Oh-hora; Sachiko Johmura; Ari Hashimoto; Masaki Hikida; Tomohiro Kurosaki
Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling.
The Journal of experimental medicine 2003;198(12):1841-51.
2003: Naoya Hatano; Yoshiko Mori; Masatsugu Oh-hora; Atsushi Kosugi; Takahiko Fujikawa; Naoya Nakai; Hitoshi Niwa; Jun-ichi Miyazaki; Toshiyuki Hamaoka; Masato Ogata
Essential role for ERK2 mitogen-activated protein kinase in placental development.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(11):847-56.
2003: Sachiko Johmura; Masatsugu Oh-hora; Kazunori Inabe; Yumiko Nishikawa; Katsuhiko Hayashi; Elena Vigorito; Daisuke Kitamura; Martin Turner; Koh Shingu; Masaki Hikida; Tomohiro Kurosaki
Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK.
Immunity 2003;18(6):777-87.
2002: Yohzo Uchida; Masato Ogata; Yoshiko Mori; Masatsugu Oh-hora; Naoya Hatano; Toshiyuki Hamaoka
Localization of PTP-FERM in nerve processes through its FERM domain.
Biochemical and biophysical research communications 2002;292(1):13-9.
1999: Masatsugu Oh-hora; Masato Ogata; Yasuo Mori; Masashi Adachi; K Imai; Atsushi Kosugi; Toshiyuki Hamaoka
Direct suppression of TCR-mediated activation of extracellular signal-regulated kinase by leukocyte protein tyrosine phosphatase, a tyrosine-specific phosphatase.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(3):1282-8.
1999: Masato Ogata; T Takada; Yasuo Mori; Yohzo Uchida; Tsuneharu Miki; A Okuyama; Atsushi Kosugi; M Sawada; Masatsugu Oh-hora; Toshiyuki Hamaoka
Regulation of phosphorylation level and distribution of PTP36, a putative protein tyrosine phosphatase, by cell-substrate adhesion.
The Journal of biological chemistry 1999;274(29):20717-24.
1999: Masato Ogata; T Takada; Yasuo Mori; Masatsugu Oh-hora; Yohzo Uchida; Atsushi Kosugi; K Miyake; Toshiyuki Hamaoka
Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells.
The Journal of biological chemistry 1999;274(18):12905-9.
1999: Masato Ogata; Masatsugu Oh-hora; Atsushi Kosugi; Toshiyuki Hamaoka
Inactivation of mitogen-activated protein kinases by a mammalian tyrosine-specific phosphatase, PTPBR7.
Biochemical and biophysical research communications 1999;256(1):52-6.
1997: S Maruo; Masatsugu Oh-hora; Hyun-Jong Ahn; Shiro Ono; M Wysocka; Y Kaneko; Hideo Yagita; K Okumura; Hitoshi Kikutani; Tadamitsu Kishimoto; Masatoshi Kobayashi; Toshiyuki Hamaoka; G Trinchieri; Hiromi Fujiwara
B cells regulate CD40 ligand-induced IL-12 production in antigen-presenting cells (APC) during T cell/APC interactions.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):120-6.
1996: S Maruo; Kazuhito Toyo-Oka; Masatsugu Oh-hora; Xu-Guang Tai; H Iwata; H Takenaka; S Yamada; Shiro Ono; Toshiyuki Hamaoka; Masatoshi Kobayashi; M Wysocka; G Trinchieri; Hiromi Fujiwara
IL-12 produced by antigen-presenting cells induces IL-2-independent proliferation of T helper cell clones.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(5):1748-55.