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Rónán O'Hagan

Research Profile

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Chemicals & Drugs

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Cell Transformation, Neoplastic

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Genes, ras

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Publications

TOP 3
Rónán C O'Hagan; Joerg Heyer
KRAS Mouse Models: Modeling Cancer Harboring KRAS Mutations.
Rónán C O'Hagan; Cameron Brennan; Andrew Strahs; Xuegong Zhang; Karuppiah Kannan; Melissa Donovan; Craig Cauwels; Norman E Sharpless; Wing Hung Wong; Lynda Chin
Array comparative genome hybridization for tumor classification and gene discovery in mouse models of malignant melanoma.
Karuppiah Kannan; Norman E Sharpless; Jin Xu; Rónán C O'Hagan; Marcus W Bosenberg; Lynda Chin
Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model.

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All Publications

2011: Rónán C O'Hagan; Joerg Heyer
KRAS Mouse Models: Modeling Cancer Harboring KRAS Mutations.
Genes & cancer 2011;2(3):335-43.
2003: Rónán C O'Hagan; Cameron Brennan; Andrew Strahs; Xuegong Zhang; Karuppiah Kannan; Melissa Donovan; Craig Cauwels; Norman E Sharpless; Wing Hung Wong; Lynda Chin
Array comparative genome hybridization for tumor classification and gene discovery in mouse models of malignant melanoma.
Cancer research 2003;63(17):5352-6.
2003: Karuppiah Kannan; Norman E Sharpless; Jin Xu; Rónán C O'Hagan; Marcus W Bosenberg; Lynda Chin
Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1221-5.
2002: Rónán C O'Hagan; Sandy Chang; richard s maser; Ramya Mohan; Steven E Artandi; Lynda Chin; Ronald A DePinho
Telomere dysfunction provokes regional amplification and deletion in cancer genomes.
Cancer cell 2002;2(2):149-55.
2002: Mingjian James You; Diego H Castrillon; Boris C Bastian; Rónán C O'Hagan; Marcus W Bosenberg; Ramon Parsons; Lynda Chin; Ronald A DePinho
Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1455-60.
2001: Norman E Sharpless; David O Ferguson; Rónán C O'Hagan; Diego H Castrillon; C Lee; P A Farazi; Scott Alson; J Fleming; C C Morton; K Frank; Lynda Chin; Frederick W Alt; Ronald A DePinho
Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.
Molecular cell 2001;8(6):1187-96.
2001: IM de Alboran; Rónán C O'Hagan; F Gärtner; Barbara A Malynn; L Davidson; R Rickert; K Rajewsky; Ronald A DePinho; Frederick W Alt
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation.
Immunity 2001;14(1):45-55.
2000: Rónán C O'Hagan; Michael Ohh; Gregory David; IM de Alboran; Frederick W Alt; William G Kaelin; Ronald A DePinho
Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression.
Genes & development 2000;14(17):2185-91.
2000: Barbara A Malynn; IM de Alboran; Rónán C O'Hagan; R Bronson; L Davidson; Ronald A DePinho; Frederick W Alt
N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation.
Genes & development 2000;14(11):1390-9.
2000: Rónán C O'Hagan; N Schreiber-Agus; Ken Chen; Gregory David; J A Engelman; R Schwab; Leila Alland; C Thomson; Donald Ronning; J C Sacchettini; P Meltzer; Ronald A DePinho
Gene-target recognition among members of the myc superfamily and implications for oncogenesis.
Nature genetics 2000;24(2):113-9.
2000: H Shen-Li; Rónán C O'Hagan; Harry Hou; James W Horner; H W Lee; Ronald A DePinho
Essential role for Max in early embryonic growth and development.
Genes & development 2000;14(1):17-22.
1999: Lynda Chin; A Tam; J Pomerantz; M Wong; J Holash; Nabeel Bardeesy; Q Shen; Rónán C O'Hagan; J Pantginis; H Zhou; James W Horner; Carlos Cordon-Cardo; G D Yancopoulos; Ronald A DePinho
Essential role for oncogenic Ras in tumour maintenance.
Nature 1999;400(6743):468-72.
1999: Roger A. Greenberg; Rónán C O'Hagan; H Deng; Q Xiao; S R Hann; R R Adams; SP Lichtsteiner; Lynda Chin; Gregg B Morin; Ronald A DePinho
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.
Oncogene 1999;18(5):1219-26.