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Peter O'Hare

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Publications

TOP 3
F Abaitua; R N Souto; H Browne; T Daikoku; Peter O'Hare
Characterization of the herpes simplex virus (HSV)-1 tegument protein VP1-2 during infection with the HSV temperature-sensitive mutant tsB7.
Ashley P E Roberts; Fernando Abaitua; Peter O'Hare; David McNab; Frazer J Rixon; David Pasdeloup
Differing roles of inner tegument proteins pUL36 and pUL37 during entry of herpes simplex virus type 1.
Helmut Hofemeister; Peter O'Hare
Nuclear pore composition and gating in herpes simplex virus-infected cells.

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All Publications

2009: F Abaitua; R N Souto; H Browne; T Daikoku; Peter O'Hare
Characterization of the herpes simplex virus (HSV)-1 tegument protein VP1-2 during infection with the HSV temperature-sensitive mutant tsB7.
The Journal of general virology 2009;90(Pt 10):2353-63.
2009: Ashley P E Roberts; Fernando Abaitua; Peter O'Hare; David McNab; Frazer J Rixon; David Pasdeloup
Differing roles of inner tegument proteins pUL36 and pUL37 during entry of herpes simplex virus type 1.
Journal of virology 2009;83(1):105-16.
2008: Helmut Hofemeister; Peter O'Hare
Nuclear pore composition and gating in herpes simplex virus-infected cells.
Journal of virology 2008;82(17):8392-9.
2008: F Abaitua; Peter O'Hare
Identification of a highly conserved, functional nuclear localization signal within the N-terminal region of herpes simplex virus type 1 VP1-2 tegument protein.
Journal of virology 2008;82(11):5234-44.
2007: Daniel Bailey; Peter O'Hare
Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response.
Antioxidants & redox signaling 2007;9(12):2305-21.
2007: Daniel Bailey; Cristina Barreca; Peter O'Hare
Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stress-regulated intramembrane proteolysis.
Traffic (Copenhagen, Denmark) 2007;8(12):1796-814.
2007: James B Morris; Helmut Hofemeister; Peter O'Hare
Herpes simplex virus infection induces phosphorylation and delocalization of emerin, a key inner nuclear membrane protein.
Journal of virology 2007;81(9):4429-37.
2006: Tom J Howat; Cristina Barreca; Peter O'Hare; Julia R Gog; Bryan T Grenfell
Modelling dynamics of the type I interferon response to in vitro viral infection.
Journal of the Royal Society, Interface / the Royal Society 2006;3(10):699-709.
2006: Cristina Barreca; Peter O'Hare
Characterization of a potent refractory state and persistence of herpes simplex virus 1 in cell culture.
Journal of virology 2006;80(18):9171-80.
2005: Daniel Bailey; Peter O'Hare
Comparison of the SUMO1 and ubiquitin conjugation pathways during the inhibition of proteasome activity with evidence of SUMO1 recycling.
The Biochemical journal 2005;392(Pt 2):271-81.
2005: G Mouzakitis; John McLauchlan; Cristina Barreca; Lisa A Kueltzo; Peter O'Hare
Characterization of VP22 in herpes simplex virus-infected cells.
Journal of virology 2005;79(19):12185-98.
2005: Bi-Tzen Juang; Ander Izeta; Peter O'Hare; Ben F Luisi
Purification and characterization of the Caenorhabditis elegans HCF protein and domains of human HCF.
Biochemistry 2005;44(30):10396-405.
2005: Helmut Hofemeister; Peter O'Hare
Analysis of the localization and topology of nurim, a polytopic protein tightly associated with the inner nuclear membrane.
The Journal of biological chemistry 2005;280(4):2512-21.
2004: Cristina Barreca; Peter O'Hare
Suppression of herpes simplex virus 1 in MDBK cells via the interferon pathway.
Journal of virology 2004;78(16):8641-53.
2004: Sylvie La Boissière; Ander Izeta; Sophie Malcomber; Peter O'Hare
Compartmentalization of VP16 in cells infected with recombinant herpes simplex virus expressing VP16-green fluorescent protein fusion proteins.
Journal of virology 2004;78(15):8002-14.
2004: Daniel Bailey; Peter O'Hare
Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1.
The Journal of biological chemistry 2004;279(1):692-703.
2003: David Zavaglia; Nadia Normand; Neil Brewis; Peter O'Hare; Marie-Christine Favrot; Jean-Luc Coll
VP22-mediated and light-activated delivery of an anti-c-raf1 antisense oligonucleotide improves its activity after intratumoral injection in nude mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(5):840-5.
2003: Ander Izeta; Sophie Malcomber; Delia O'Rourke; Jonathan Hodgkin; Peter O'Hare
A C-terminal targeting signal controls differential compartmentalisation of Caenorhabditis elegans host cell factor (HCF) to the nucleus or mitochondria.
European journal of cell biology 2003;82(10):495-504.
2003: Hans van Leeuwen; Mitsuru Okuwaki; Rui Hong; Debabrata Chakravarti; Kyosuke Nagata; Peter O'Hare
Herpes simplex virus type 1 tegument protein VP22 interacts with TAF-I proteins and inhibits nucleosome assembly but not regulation of histone acetylation by INHAT.
The Journal of general virology 2003;84(Pt 9):2501-10.
2003: Ander Izeta; Sophie Malcomber; Peter O'Hare
Primary structure and compartmentalization of Drosophila melanogaster host cell factor.
Gene 2003;305(2):175-83.
2003: Neil Brewis; A Phelan; Nadia Normand; E Choolun; Peter O'Hare
Particle assembly incorporating a VP22-BH3 fusion protein, facilitating intracellular delivery, regulated release, and apoptosis.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(2):262-70.
2002: Daniel Bailey; Peter O'Hare
Herpes simplex virus 1 ICP0 co-localizes with a SUMO-specific protease.
The Journal of general virology 2002;83(Pt 12):2951-64.
2002: Ana Martin; Peter O'Hare; John McLauchlan; Gillian Elliott
Herpes simplex virus tegument protein VP22 contains overlapping domains for cytoplasmic localization, microtubule interaction, and chromatin binding.
Journal of virology 2002;76(10):4961-70.
2002: Hans van Leeuwen; Gill Elliott; Peter O'Hare
Evidence of a role for nonmuscle myosin II in herpes simplex virus type 1 egress.
Journal of virology 2002;76(7):3471-81.
2001: Wolfgang A Wybranietz; Christine D Gross; A Phelan; Peter O'Hare; Martin Spiegel; Florian Graepler; Michael Bitzer; P Stähler; Michael Gregor; Ulrich M Lauer
Enhanced suicide gene effect by adenoviral transduction of a VP22-cytosine deaminase (CD) fusion gene.
Gene therapy 2001;8(21):1654-64.
2001: E S Scott; Sophie Malcomber; Peter O'Hare
Nuclear translocation and activation of the transcription factor NFAT is blocked by herpes simplex virus infection.
Journal of virology 2001;75(20):9955-65.
2001: E S Scott; Peter O'Hare
Fate of the inner nuclear membrane protein lamin B receptor and nuclear lamins in herpes simplex virus type 1 infection.
Journal of virology 2001;75(18):8818-30.
2001: Nadia Normand; Hans van Leeuwen; Peter O'Hare
Particle formation by a conserved domain of the herpes simplex virus protein VP22 facilitating protein and nucleic acid delivery.
The Journal of biological chemistry 2001;276(18):15042-50.
2000: M Grapes; Peter O'Hare
Differences in determinants required for complex formation and transactivation in related VP16 proteins.
Journal of virology 2000;74(21):10112-21.
2000: Lisa A Kueltzo; Nadia Normand; Peter O'Hare; C Russell Middaugh
Conformational lability of herpesvirus protein VP22.
The Journal of biological chemistry 2000;275(43):33213-21.
2000: Gillian Elliott; Peter O'Hare
Cytoplasm-to-nucleus translocation of a herpesvirus tegument protein during cell division.
Journal of virology 2000;74(5):2131-41.
2000: Neil Brewis; A Phelan; J Webb; J Drew; Gill Elliott; Peter O'Hare
Evaluation of VP22 spread in tissue culture.
Journal of virology 2000;74(2):1051-6.
2000: S LaBoissière; Peter O'Hare
Analysis of HCF, the cellular cofactor of VP16, in herpes simplex virus-infected cells.
Journal of virology 2000;74(1):99-109.
1999: Gillian Elliott; D O'Reilly; Peter O'Hare
Identification of phosphorylation sites within the herpes simplex virus tegument protein VP22.
Journal of virology 1999;73(7):6203-6.
1999: T A Hughes; Sylvie La Boissière; Peter O'Hare
Analysis of functional domains of the host cell factor involved in VP16 complex formation.
The Journal of biological chemistry 1999;274(23):16437-43.
1999: Gill Elliott; Peter O'Hare
Live-cell analysis of a green fluorescent protein-tagged herpes simplex virus infection.
Journal of virology 1999;73(5):4110-9.
1999: Sylvie La Boissière; T Hughes; Peter O'Hare
HCF-dependent nuclear import of VP16.
The EMBO journal 1999;18(2):480-9.
1999: Gillian Elliott; Peter O'Hare
Intercellular trafficking of VP22-GFP fusion proteins.
Gene therapy 1999;6(1):149-51.
1999: M Sirac Dilber; A Phelan; Alar Aints; Abdalla J Mohamed; Gill Elliott; C I Edvard Smith; Peter O'Hare
Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22.
Gene therapy 1999;6(1):12-21.
1998: Gillian Elliott; Peter O'Hare
Herpes simplex virus type 1 tegument protein VP22 induces the stabilization and hyperacetylation of microtubules.
Journal of virology 1998;72(8):6448-55.
1998: A Phelan; G Elliott; Peter O'Hare
Intercellular delivery of functional p53 by the herpesvirus protein VP22.
Nature biotechnology 1998;16(5):440-3.
1998: Delia O'Rourke; G Elliott; M Papworth; R Everett; Peter O'Hare
Examination of determinants for intranuclear localization and transactivation within the RING finger of herpes simplex virus type 1 IE110k protein.
The Journal of general virology 1998;79 ( Pt 3)():537-48.
1997: S LaBoissière; S Walker; Peter O'Hare
Concerted activity of host cell factor subregions in promoting stable VP16 complex assembly and preventing interference by the acidic activation domain.
Molecular and cellular biology 1997;17(12):7108-18.
1997: D O'Reilly; O Hanscombe; Peter O'Hare
A single serine residue at position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II.
The EMBO journal 1997;16(9):2420-30.
1997: G Elliott; Peter O'Hare
Intercellular trafficking and protein delivery by a herpesvirus structural protein.
Cell 1997;88(2):223-33.
1996: G Elliott; D O'Reilly; Peter O'Hare
Phosphorylation of the herpes simplex virus type 1 tegument protein VP22.
Virology 1996;226(1):140-5.
1996: Vikram Misra; S Walter; P Yang; S Hayes; Peter O'Hare
Conformational alteration of Oct-1 upon DNA binding dictates selectivity in differential interactions with related transcriptional coactivators.
Molecular and cellular biology 1996;16(8):4404-13.
1995: G Elliott; G Mouzakitis; Peter O'Hare
VP16 interacts via its activation domain with VP22, a tegument protein of herpes simplex virus, and is relocated to a novel macromolecular assembly in coexpressing cells.
Journal of virology 1995;69(12):7932-41.
1995: R Everett; Peter O'Hare; D O'Rourke; P Barlow; Anne Orr
Point mutations in the herpes simplex virus type 1 Vmw110 RING finger helix affect activation of gene expression, viral growth, and interaction with PML-containing nuclear structures.
Journal of virology 1995;69(11):7339-44.
1995: G Elliott; Peter O'Hare
Equine herpesvirus 1 gene 12, the functional homologue of herpes simplex virus VP16, transactivates via octamer sequences in the equine herpesvirus IE gene promoter.
Virology 1995;213(1):258-62.
1995: Vikram Misra; S Walker; S Hayes; Peter O'Hare
The bovine herpesvirus alpha gene trans-inducing factor activates transcription by mechanisms different from those of its herpes simplex virus type 1 counterpart VP16.
Journal of virology 1995;69(9):5209-16.
1994: S Walker; S Hayes; Peter O'Hare
Site-specific conformational alteration of the Oct-1 POU domain-DNA complex as the basis for differential recognition by Vmw65 (VP16).
Cell 1994;79(5):841-52.
1994: Vikram Misra; A C Bratanich; D Carpenter; Peter O'Hare
Protein and DNA elements involved in transactivation of the promoter of the bovine herpesvirus (BHV) 1 IE-1 transcription unit by the BHV alpha gene trans-inducing factor.
Journal of virology 1994;68(8):4898-909.
1994: A H Batchelor; K W Wilcox; Peter O'Hare
Binding and repression of the latency-associated promoter of herpes simplex virus by the immediate early 175K protein.
The Journal of general virology 1994;75 ( Pt 4)():753-67.
1993: D O'Rourke; Peter O'Hare
Mutually exclusive binding of two cellular factors within a critical promoter region of the gene for the IE110k protein of herpes simplex virus.
Journal of virology 1993;67(12):7201-14.
1993: S Walker; R Greaves; Peter O'Hare
Transcriptional activation by the acidic domain of Vmw65 requires the integrity of the domain and involves additional determinants distinct from those necessary for TFIIB binding.
Molecular and cellular biology 1993;13(9):5233-44.
1993: S Hayes; Peter O'Hare
Mapping of a major surface-exposed site in herpes simplex virus protein Vmw65 to a region of direct interaction in a transcription complex assembly.
Journal of virology 1993;67(2):852-62.
1992: A H Batchelor; Peter O'Hare
Localization of cis-acting sequence requirements in the promoter of the latency-associated transcript of herpes simplex virus type 1 required for cell-type-specific activity.
Journal of virology 1992;66(6):3573-82.
1992: Peter O'Hare; G Williams
Structural studies of the acidic transactivation domain of the Vmw65 protein of herpes simplex virus using 1H NMR.
Biochemistry 1992;31(16):4150-6.
1991: R F Greaves; Peter O'Hare
Sequence, function, and regulation of the Vmw65 gene of herpes simplex virus type 2.
Journal of virology 1991;65(12):6705-13.
1990: M Katan; A Haigh; C P Verrijzer; Peter C van der Vliet; Peter O'Hare
Characterization of a cellular factor which interacts functionally with Oct-1 in the assembly of a multicomponent transcription complex.
Nucleic acids research 1990;18(23):6871-80.
1990: A H Batchelor; Peter O'Hare
Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.
Journal of virology 1990;64(7):3269-79.
1990: R F Greaves; Peter O'Hare
Structural requirements in the herpes simplex virus type 1 transactivator Vmw65 for interaction with the cellular octamer-binding protein and target TAATGARAT sequences.
Journal of virology 1990;64(6):2716-24.
1990: A Haigh; R Greaves; Peter O'Hare
Interference with the assembly of a virus-host transcription complex by peptide competition.
Nature 1990;344(6263):257-9.
1989: Colin R Goding; Peter O'Hare
Herpes simplex virus Vmw65-octamer binding protein interaction: a paradigm for combinatorial control of transcription.
Virology 1989;173(2):363-7.
1989: D J Cousens; R Greaves; Colin R Goding; Peter O'Hare
The C-terminal 79 amino acids of the herpes simplex virus regulatory protein, Vmw65, efficiently activate transcription in yeast and mammalian cells in chimeric DNA-binding proteins.
The EMBO journal 1989;8(8):2337-42.
1989: R Greaves; Peter O'Hare
Separation of requirements for protein-DNA complex assembly from those for functional activity in the herpes simplex virus regulatory protein Vmw65.
Journal of virology 1989;63(4):1641-50.
1988: Peter O'Hare; Colin R Goding; A Haigh
Direct combinatorial interaction between a herpes simplex virus regulatory protein and a cellular octamer-binding factor mediates specific induction of virus immediate-early gene expression.
The EMBO journal 1988;7(13):4231-8.
1988: Peter O'Hare; Colin R Goding
Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation.
Cell 1988;52(3):435-45.