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Kazuhito Ohishi

Research Profile

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Procedures

Cloning, Molecular

Living Beings

Anatomy

CHO Cells

Disorders

Paroxysmal Hemoglobinuria

Physiology

Co-author Network

Publications

TOP 3
Kazuhito Ohishi; Toru Nakano
A forward genetic screen to study mammalian RNA interference: essential role of RNase IIIa domain of Dicer1 in 3' strand cleavage of dsRNA in vivo.
Yeonchul Hong; Kisaburo Nagamune; Kazuhito Ohishi; Yasu S Morita; Hisashi Ashida; Yusuke Maeda; Taroh Kinoshita
TbGPI16 is an essential component of GPI transamidase in Trypanosoma brucei.
Kazuhito Ohishi; Taroh Kinoshita
[Complement system in host defense].

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All Publications

2012: Kazuhito Ohishi; Toru Nakano
A forward genetic screen to study mammalian RNA interference: essential role of RNase IIIa domain of Dicer1 in 3' strand cleavage of dsRNA in vivo.
The FEBS journal 2012;279(5):832-43.
2006: Yeonchul Hong; Kisaburo Nagamune; Kazuhito Ohishi; Yasu S Morita; Hisashi Ashida; Yusuke Maeda; Taroh Kinoshita
TbGPI16 is an essential component of GPI transamidase in Trypanosoma brucei.
FEBS letters 2006;580(2):603-6.
2005: Kazuhito Ohishi; Taroh Kinoshita
[Complement system in host defense].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 4():263-8.
2005: Nobue Shishioh; Yeongjin Hong; Kazuhito Ohishi; Hisashi Ashida; Yusuke Maeda; Taroh Kinoshita
GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol.
The Journal of biological chemistry 2005;280(10):9728-34.
2003: Kisaburo Nagamune; Kazuhito Ohishi; Hisashi Ashida; Yeonchul Hong; Jun Hino; Kenji Kangawa; Norimitsu Inoue; Yusuke Maeda; Taroh Kinoshita
GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunits.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10682-7.
2003: Yeongjin Hong; Kazuhito Ohishi; Ji Young Kang; Satoshi Tanaka; Norimitsu Inoue; Jun-ichi Nishimura; Yusuke Maeda; Taroh Kinoshita
Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins.
Molecular biology of the cell 2003;14(5):1780-9.
2003: Kazuhito Ohishi; Kisaburo Nagamune; Yusuke Maeda; Taroh Kinoshita
Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge.
The Journal of biological chemistry 2003;278(16):13959-67.
2002: Yoshiko Murakami; Hiroshi Kosaka; Yusuke Maeda; Jun-ichi Nishimura; Norimitsu Inoue; Kazuhito Ohishi; Masaru Okabe; Junji Takeda; Taroh Kinoshita
Inefficient response of T lymphocytes to glycosylphosphatidylinositol anchor-negative cells: implications for paroxysmal nocturnal hemoglobinuria.
Blood 2002;100(12):4116-22.
2002: Yeongjin Hong; Kazuhito Ohishi; Norimitsu Inoue; Ji Young Kang; Hiroaki Shime; Yasuhiko Horiguchi; F Gisou van der Goot; Nakaba Sugimoto; Taroh Kinoshita
Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin.
The EMBO journal 2002;21(19):5047-56.
2002: Jun-ichi Nishimura Ji; Toshiyuki Hirota; Yuzuru Kanakura; Takashi Machii; Takashi Kageyama; Shoichi Doi; Hiroshi Wada; Toru Masaoka; Yoshio Kanayama; Hiroshi Fujii; Norimitsu Inoue; Maki Kuwayama; Norimitsu Inoue; Kazuhito Ohishi; Taroh Kinoshita
Long-term support of hematopoiesis by a single stem cell clone in patients with paroxysmal nocturnal hemoglobinuria.
Blood 2002;99(8):2748-51.
2001: Kazuhito Ohishi; Norimitsu Inoue; Taroh Kinoshita
PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.
The EMBO journal 2001;20(15):4088-98.
2001: Yusuke Maeda; R Watanabe; C L Harris; Yeongjin Hong; Kazuhito Ohishi; K Kinoshita; Taroh Kinoshita
PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER.
The EMBO journal 2001;20(1-2):250-61.
2000: Kisaburo Nagamune; T Nozaki; Yusuke Maeda; Kazuhito Ohishi; T Fukuma; Toshiro Hara; R T Schwarz; C Sutterlin; Reto Brun; H Riezman; Taroh Kinoshita
Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(19):10336-41.
2000: Yeongjin Hong; Yusuke Maeda; R Watanabe; Norimitsu Inoue; Kazuhito Ohishi; Taroh Kinoshita
Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol.
The Journal of biological chemistry 2000;275(27):20911-9.
2000: Kazuhito Ohishi; Norimitsu Inoue; Yusuke Maeda; Jun Takeda; H Riezman; Taroh Kinoshita
Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins.
Molecular biology of the cell 2000;11(5):1523-33.
2000: Maki Kuwayama; Taroh Kinoshita; Kazuhito Ohishi
[Paroxysmal nocturnal hemoglobinuria].
Ryōikibetsu shōkōgun shirīzu 2000;(32):236-8.
1999: Yeongjin Hong; Yusuke Maeda; R Watanabe; Kazuhito Ohishi; M Mishkind; H Riezman; Taroh Kinoshita
Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol.
The Journal of biological chemistry 1999;274(49):35099-106.
1999: Yeongjin Hong; Kazuhito Ohishi; R Watanabe; Y Endo; Yusuke Maeda; Taroh Kinoshita
GPI1 stabilizes an enzyme essential in the first step of glycosylphosphatidylinositol biosynthesis.
The Journal of biological chemistry 1999;274(26):18582-8.
1999: R Watanabe; Kazuhito Ohishi; Yusuke Maeda; Norihiro Nakamura; Taroh Kinoshita
Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis.
The Biochemical journal 1999;339 ( Pt 1)():185-92.
1999: M Nozaki; Kazuhito Ohishi; N Yamada; Taroh Kinoshita; Andras Nagy; Jun Takeda
Developmental abnormalities of glycosylphosphatidylinositol-anchor-deficient embryos revealed by Cre/loxP system.
Laboratory investigation; a journal of technical methods and pathology 1999;79(3):293-9.
1999: Norimitsu Inoue; Kazuhito Ohishi; Y Endo; T Fujita; Jun Takeda; Taroh Kinoshita
Human and mouse GPAA1 (Glycosylphosphatidylinositol anchor attachment 1) genes: genomic structures, chromosome loci and the presence of a minor class intron.
Cytogenetics and cell genetics 1999;84(3-4):199-205.
1998: Yusuke Maeda; S Tomita; R Watanabe; Kazuhito Ohishi; Taroh Kinoshita
DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.
The EMBO journal 1998;17(17):4920-9.
1998: S Tomita; Norimitsu Inoue; Yusuke Maeda; Kazuhito Ohishi; Jun Takeda; Taroh Kinoshita
A homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cells.
The Journal of biological chemistry 1998;273(15):9249-54.
1997: Yeongjin Hong; Kazuhito Ohishi; Norimitsu Inoue; Y Endo; T Fujita; Jun Takeda; Taroh Kinoshita
Structures and chromosomal localizations of the glycosylphosphatidylinositol synthesis gene PIGC and its pseudogene PIGCP1.
Genomics 1997;44(3):347-9.
1997: Taroh Kinoshita; Kazuhito Ohishi; Jun Takeda
GPI-anchor synthesis in mammalian cells: genes, their products, and a deficiency.
Journal of biochemistry 1997;122(2):251-7.
1996: M Takahashi; Norimitsu Inoue; Kazuhito Ohishi; Yusuke Maeda; Norihiro Nakamura; Y Endo; T Fujita; Jun Takeda; Taroh Kinoshita
PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor.
The EMBO journal 1996;15(16):4254-61.
1996: Kazuhito Ohishi; Y Kurimoto; Norimitsu Inoue; Y Endo; Jun Takeda; Taroh Kinoshita
Cloning and characterization of the murine GPI anchor synthesis gene Pigf, a homologue of the human PIGF gene.
Genomics 1996;34(3):340-6.
1995: Kazuhito Ohishi; Norimitsu Inoue; Y Endo; T Fujita; Jun Takeda; Taroh Kinoshita
Structure and chromosomal localization of the GPI-anchor synthesis gene PIGF and its pseudogene psi PIGF.
Genomics 1995;29(3):804-7.