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Suzanne Benjannet

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Heiner K. Berthold; Suzanne Benjannet; Nabil G Seidah; Ioanna Gouni-Berthold
Evidence from a randomized trial that simvastatin, but not ezetimibe, upregulates circulating PCSK9 levels.
Suzanne Benjannet; Michel Chrétien; Josée Hamelin; Nabil G Seidah
Loss- and gain-of-function PCSK9 variants: cleavage specificity, dominant negative effects, and low density lipoprotein receptor (LDLR) degradation.
Marianne Abifadel; Suzanne Benjannet; Dominique Bonnefont-Rousselot; Eric Bruckert; Valérie Carreau; Alain Carrié; John Chapman; Philippe Couvert; Maryse Guerin; Josée Hamelin; Zélie Julia; Wilfried Le Goff; Olivier Meilhac; Jean-Baptiste Michel; Annik Prat; Jean-Pierre Rabès; Nabil G Seidah; Laurent Tosolini; Mathilde Varret; catherine boileau
Identification and characterization of new gain-of-function mutations in the PCSK9 gene responsible for autosomal dominant hypercholesterolemia.

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All Publications

2013: Heiner K. Berthold; Suzanne Benjannet; Nabil G Seidah; Ioanna Gouni-Berthold
Evidence from a randomized trial that simvastatin, but not ezetimibe, upregulates circulating PCSK9 levels.
PloS one 2013;8(3):e60095.
2012: Suzanne Benjannet; Michel Chrétien; Josée Hamelin; Nabil G Seidah
Loss- and gain-of-function PCSK9 variants: cleavage specificity, dominant negative effects, and low density lipoprotein receptor (LDLR) degradation.
The Journal of biological chemistry 2012;287(40):33745-55.
2012: Marianne Abifadel; Suzanne Benjannet; Dominique Bonnefont-Rousselot; Eric Bruckert; Valérie Carreau; Alain Carrié; John Chapman; Philippe Couvert; Maryse Guerin; Josée Hamelin; Zélie Julia; Wilfried Le Goff; Olivier Meilhac; Jean-Baptiste Michel; Annik Prat; Jean-Pierre Rabès; Nabil G Seidah; Laurent Tosolini; Mathilde Varret; catherine boileau
Identification and characterization of new gain-of-function mutations in the PCSK9 gene responsible for autosomal dominant hypercholesterolemia.
Atherosclerosis 2012;223(2):394-400.
2012: Caroline Richard; Nabil G Seidah; Alice H Lichtenstein; Suzanne Benjannet; Patrick Couture; Sophie Desroches; Benoît Lamarche
Effect of the Mediterranean diet with and without weight loss on surrogate markers of cholesterol homeostasis in men with the metabolic syndrome.
The British journal of nutrition 2012;107(5):705-11.
2011: Wesley F Zandberg; Suzanne Benjannet; Josée Hamelin; B Mario Pinto; Nabil G Seidah
N-glycosylation controls trafficking, zymogen activation and substrate processing of proprotein convertases PC1/3 and subtilisin kexin isozyme-1.
Glycobiology 2011;21(10):1290-300.
2011: Delia Susan-Resiga; Dorota Szumska; Marie-Claude Asselin; Suzanne Benjannet; Shoumo Bhattacharya; Ann Chamberland; Daniel Constam; Robert Day; Rachid Essalmani; Josée Hamelin; Annik Prat; Nabil G Seidah
Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.
The Journal of biological chemistry 2011;286(26):22785-94.
2011: Estelle Rousselet; Suzanne Benjannet; Edwidge Marcinkiewicz; Marie-Claude Asselin; Claude Lazure; Nabil G Seidah
Proprotein convertase PC7 enhances the activation of the EGF receptor pathway through processing of the EGF precursor.
The Journal of biological chemistry 2011;286(11):9185-95.
2011: A Tremblay; Benoît Lamarche; Valéry Lemelin; Lizbeth Hoos; Suzanne Benjannet; Nabil G Seidah; Harry R Davis; Patrick Couture
Atorvastatin increases intestinal expression of NPC1L1 in hyperlipidemic men.
Journal of lipid research 2011;52(3):558-65.
2011: Estelle Rousselet; Suzanne Benjannet; Josée Hamelin; Maryssa Canuel; Nabil G Seidah
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
The Journal of biological chemistry 2011;286(4):2728-38.
2010: Suzanne Benjannet; Yascara Grisel Luna Saavedra; Josée Hamelin; Marie-Claude Asselin; Rachid Essalmani; Antonella Pasquato; Peter Lemaire; Gerald Duke; Bowman Miao; Franck Duclos; Rex Parker; Gaétan Mayer; Nabil G Seidah
Effects of the prosegment and pH on the activity of PCSK9: evidence for additional processing events.
The Journal of biological chemistry 2010;285(52):40965-78.
2010: Geneviève Dubuc; Michel Tremblay; Guillaume Paré; Hélène Jacques; Josée Hamelin; Suzanne Benjannet; Lucie Boulet; Jacques Genest; Lise Bernier; Nabil G Seidah; Jean Davignon
A new method for measurement of total plasma PCSK9: clinical applications.
Journal of lipid research 2010;51(1):140-9.
2008: Simona Ozden; Marianne Lucas-Hourani; Pierre-Emmanuel Ceccaldi; Ajoy Basak; Menogh Valentine; Suzanne Benjannet; Josée Hamelin; Yves Jacob; Kamel Mamchaoui; Vincent Mouly; Philippe Desprès; Antoine Gessain; Gillian Butler-Browne; Michel Chrétien; Frédéric Tangy; Pierre-Olivier Vidalain; Nabil G Seidah
Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein.
The Journal of biological chemistry 2008;283(32):21899-908.
2008: Steve Poirier; Gaetan Mayer; Suzanne Benjannet; Eric Bergeron; Jadwiga Marcinkiewicz; Nasha Nassoury; Harald Mayer; Johannes Nimpf; Annik Prat; Nabil G Seidah
The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2.
The Journal of biological chemistry 2008;283(4):2363-72.
2007: Philomena Pullikotil; Suzanne Benjannet; Janice Mayne; Nabil G Seidah
The proprotein convertase SKI-1/S1P: alternate translation and subcellular localization.
The Journal of biological chemistry 2007;282(37):27402-13.
2007: Nasha Nassoury; Daniel A Blasiole; Angie Tebon Oler; Suzanne Benjannet; Josée Hamelin; Poupon Viviane; Peter S McPherson; Alan D Attie; Annik Prat; Nabil G Seidah
The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR.
Traffic (Copenhagen, Denmark) 2007;8(6):718-32.
2006: Suzanne Benjannet; David Rhainds; Josée Hamelin; Nasha Nassoury; Nabil G Seidah
The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications.
The Journal of biological chemistry 2006;281(41):30561-72.
2005: Weijun Jin; Ilia V Fuki; Nabil G Seidah; Suzanne Benjannet; Jane M Glick; Daniel J Rader
Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase.
The Journal of biological chemistry 2005;280(44):36551-9.
2005: Alexandre Salvas; Suzanne Benjannet; Timothy L Reudelhuber; Michel Chrétien; Nabil G Seidah
Evidence for proprotein convertase activity in the endoplasmic reticulum/early Golgi.
FEBS letters 2005;579(25):5621-5.
2005: Geraldine Siegfried; Ajoy Basak; Wendy Prichett-Pejic; Nathalie Scamuffa; Liming Ma; Suzanne Benjannet; John P Veinot; Fabien Calvo; Nabil G Seidah; Abdel-Majid Khatib
Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases.
Oncogene 2005;24(46):6925-35.
2005: Martin J Vincent; Eric Bergeron; Suzanne Benjannet; Bobbie R Erickson; Pierre E Rollin; Thomas G Ksiazek; Nabil G Seidah; Stuart T Nichol
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.
Virology journal 2005;2():69.
2005: Louise Wickham; Suzanne Benjannet; Edwige Marcinkiewicz; Michel Chretien; Nabil G Seidah
Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin.
Journal of neurochemistry 2005;92(1):93-102.
2004: Suzanne Benjannet; James A Cromlish; Karidia Diallo; Michel Chrétien; Nabil G Seidah
The metabolism of beta-amyloid converting enzyme and beta-amyloid precursor protein processing.
Biochemical and biophysical research communications 2004;325(1):235-42.
2004: Suzanne Benjannet; David Rhainds; Rachid Essalmani; Janice Mayne; Louise Wickham; Weijun Jin; Marie-Claude Asselin; Josée Hamelin; Mathilde Varret; Delphine Allard; Mélanie Trillard; Marianne Abifadel; Angie Tebon; Alan D Attie; Daniel J Rader; catherine boileau; Louise Brissette; Michel Chrétien; Annik Prat; Nabil G Seidah
NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol.
The Journal of biological chemistry 2004;279(47):48865-75.
2003: Geraldine Siegfried; Ajoy Basak; James A Cromlish; Suzanne Benjannet; Jadwiga Marcinkiewicz; Michel Chrétien; Nabil G Seidah; Abdel-Majid Khatib
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis.
The Journal of clinical investigation 2003;111(11):1723-32.
2003: Marianne Abifadel; Mathilde Varret; Jean-Pierre Rabès; Delphine Allard; Khadija Ouguerram; Martine Devillers; Corinne Cruaud; Suzanne Benjannet; Louise Wickham; Danièle Erlich; Aurélie Derré; Ludovic Villéger; Michel Farnier; Isabel Beucler; Eric Bruckert; Jean CHAMBAZ; Bernard Chanu; Jean-Michel Lecerf; Gerald Luc; Philippe Moulin; Jean Weissenbach; Annick Prat; Michel Krempf; Claudine Junien; Nabil G Seidah; catherine boileau
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.
Nature genetics 2003;34(2):154-6.
2003: Geraldine Siegfried; Abdel-Majid Khatib; Suzanne Benjannet; Michel Chrétien; Nabil G Seidah
The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity.
Cancer research 2003;63(7):1458-63.
2003: Nabil G Seidah; Suzanne Benjannet; Louise Wickham; Jadwiga Marcinkiewicz; Stephanie Belanger Jasmin; Stefano Stifani; Ajoy Basak; Annik Prat; Michel Chretien
The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):928-33.
2002: Aram Elagoz; Suzanne Benjannet; Aida Mammarbassi; Louise Wickham; Nabil G Seidah
Biosynthesis and cellular trafficking of the convertase SKI-1/S1P: ectodomain shedding requires SKI-1 activity.
The Journal of biological chemistry 2002;277(13):11265-75.
2001: Suzanne Benjannet; A Elagoz; Louise Wickham; M Mamarbachi; JS Munzer; Ajoy Basak; Claude Lazure; James A Cromlish; Sangram S Sisodia; F Checler; Michel Chrétien; Nabil G Seidah
Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.
The Journal of biological chemistry 2001;276(14):10879-87.
2000: Jean-Claude Lissitzky; José Luis; JS Munzer; Suzanne Benjannet; Fabrice Parat; Michel Chrétien; Jacques Marvaldi; Nabil G Seidah
Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7.
The Biochemical journal 2000;346 Pt 1():133-8.
2000: BB Touré; JS Munzer; Ajoy Basak; Suzanne Benjannet; J Rochemont; Claude Lazure; Michel Chrétien; Nabil G Seidah
Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegment.
The Journal of biological chemistry 2000;275(4):2349-58.
1999: M Zhong; JS Munzer; Ajoy Basak; Suzanne Benjannet; SJ Mowla; jeff Keyser; Michel Chrétien; Nabil G Seidah
The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity.
The Journal of biological chemistry 1999;274(48):33913-20.
1999: Nabil G Seidah; Suzanne Benjannet; Josée Hamelin; Aida M Mamarbachi; Ajoy Basak; Jadwiga Marcinkiewicz; Majambu Mbikay; Michel Chrétien; Mieczyslaw Marcinkiewicz
The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1.
Annals of the New York Academy of Sciences 1999;885():57-74.
1999: Nabil G Seidah; SJ Mowla; Josée Hamelin; Aida M Mamarbachi; Suzanne Benjannet; BB Touré; Ajoy Basak; JS Munzer; Jadwiga Marcinkiewicz; M Zhong; J C Barale; Claude Lazure; Richard A Murphy; Michel Chrétien; Mieczyslaw Marcinkiewicz
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1321-6.
1998: S E Girardin; Suzanne Benjannet; J C Barale; Michel Chrétien; Nabil G Seidah
The LIM homeobox protein mLIM3/Lhx3 induces expression of the prolactin gene by a Pit-1/GHF-1-independent pathway in corticotroph AtT20 cells.
FEBS letters 1998;431(3):333-8.
1998: Suzanne Benjannet; Aida M Mamarbachi; Josée Hamelin; D Savaria; JS Munzer; Michel Chrétien; Nabil G Seidah
Residues unique to the pro-hormone convertase PC2 modulate its autoactivation, binding to 7B2 and enzymatic activity.
FEBS letters 1998;428(1-2):37-42.
1997: Suzanne Benjannet; D Savaria; Andrea Laslop; JS Munzer; Michel Chrétien; Mieczyslaw Marcinkiewicz; Nabil G Seidah
Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway.
The Journal of biological chemistry 1997;272(42):26210-8.
1997: J Lusson; Suzanne Benjannet; Josée Hamelin; D Savaria; Michel Chrétien; Nabil G Seidah
The integrity of the RRGDL sequence of the proprotein convertase PC1 is critical for its zymogen and C-terminal processing and for its cellular trafficking.
The Biochemical journal 1997;326 ( Pt 3)():737-44.
1997: JS Munzer; Ajoy Basak; M Zhong; Aida M Mamarbachi; Josée Hamelin; D Savaria; Claude Lazure; G N Hendy; Suzanne Benjannet; Michel Chrétien; Nabil G Seidah
In vitro characterization of the novel proprotein convertase PC7.
The Journal of biological chemistry 1997;272(32):19672-81.
1997: jeff Keyser; Suzanne Benjannet; D Savaria; Nabil G Seidah
Comparative functional role of PC7 and furin in the processing of the HIV envelope glycoprotein gp160.
FEBS letters 1997;405(1):68-72.
1996: M Zhong; Suzanne Benjannet; Claude Lazure; S Munzer; Nabil G Seidah
Functional analysis of human PACE4-A and PACE4-C isoforms: identification of a new PACE4-CS isoform.
FEBS letters 1996;396(1):31-6.
1996: Nabil G Seidah; Suzanne Benjannet; S Pareek; D Savaria; Josée Hamelin; B Goulet; J Laliberte; Claude Lazure; Michel Chrétien; R A Murphy
Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases.
The Biochemical journal 1996;314 ( Pt 3)():951-60.
1996: F Vollenweider; Suzanne Benjannet; jeff Keyser; D Savaria; Claude Lazure; Gary Thomas; Michel Chrétien; Nabil G Seidah
Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.
The Biochemical journal 1996;314 ( Pt 2)():521-32.
1996: Nabil G Seidah; Suzanne Benjannet; S Pareek; Michel Chrétien; R A Murphy
Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases.
FEBS letters 1996;379(3):247-50.
1995: Suzanne Benjannet; D Savaria; Michel Chrétien; Nabil G Seidah
7B2 is a specific intracellular binding protein of the prohormone convertase PC2.
Journal of neurochemistry 1995;64(5):2303-11.
1995: Suzanne Benjannet; J Lusson; Josée Hamelin; D Savaria; Michel Chrétien; Nabil G Seidah
Structure-function studies on the biosynthesis and bioactivity of the precursor convertase PC2 and the formation of the PC2/7B2 complex.
FEBS letters 1995;362(2):151-5.
1995: R Day; Suzanne Benjannet; L Matsuuchi; R B Kelly; M Marcinkiewicz; M Chrétien; N G Seidah
Maintained PC1 and PC2 expression in the AtT-20 variant cell line 6T3 lacking regulated secretion and POMC: restored POMC expression and regulated secretion after cAMP treatment.
DNA and cell biology 1995;14(2):175-88.
1993: Suzanne Benjannet; N Rondeau; L Paquet; A Boudreault; Claude Lazure; Michel Chrétien; Nabil G Seidah
Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2.
The Biochemical journal 1993;294 ( Pt 3)():735-43.
1993: F Jean; Ajoy Basak; N Rondeau; Suzanne Benjannet; Geoffrey N Hendy; Nabil G Seidah; Michel Chrétien; Claude Lazure
Enzymic characterization of murine and human prohormone convertase-1 (mPC1 and hPC1) expressed in mammalian GH4C1 cells.
The Biochemical journal 1993;292 ( Pt 3)():891-900.
1992: Nabil G Seidah; H Fournier; Guy Boileau; Suzanne Benjannet; N Rondeau; Michel Chrétien
The cDNA structure of the porcine pro-hormone convertase PC2 and the comparative processing by PC1 and PC2 of the N-terminal glycopeptide segment of porcine POMC.
FEBS letters 1992;310(3):235-9.
1992: Suzanne Benjannet; Timothy L Reudelhuber; C Mercure; N Rondeau; Michel Chrétien; Nabil G Seidah
Proprotein conversion is determined by a multiplicity of factors including convertase processing, substrate specificity, and intracellular environment. Cell type-specific processing of human prorenin by the convertase PC1.
The Journal of biological chemistry 1992;267(16):11417-23.
1992: Nabil G Seidah; Robert Day; Suzanne Benjannet; N Rondeau; A Boudreault; Timothy L Reudelhuber; M K Schafer; S J Watson; Michel Chrétien
The prohormone and proprotein processing enzymes PC1 and PC2: structure, selective cleavage of mouse POMC and human renin at pairs of basic residues, cellular expression, tissue distribution, and mRNA regulation.
NIDA research monograph 1992;126():132-50.
1991: Claude Lazure; Suzanne Benjannet; Nabil G Seidah; Michel Chrétien
Processed forms of neuroendocrine proteins 7B2 and secretogranin II are found in porcine pituitary extracts.
International journal of peptide and protein research 1991;38(4):392-400.
1991: Nabil G Seidah; M G Mattei; L Gaspar; Suzanne Benjannet; Majambu Mbikay; Michel Chrétien
Chromosomal assignments of the genes for neuroendocrine convertase PC1 (NEC1) to human 5q15-21, neuroendocrine convertase PC2 (NEC2) to human 20p11.1-11.2, and furin (mouse 7[D1-E2] region).
Genomics 1991;11(1):103-7.
1991: Suzanne Benjannet; N Rondeau; Robert Day; Michel Chrétien; Nabil G Seidah
PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3564-8.
1991: Nabil G Seidah; Mieczyslaw Marcinkiewicz; Suzanne Benjannet; L Gaspar; G Beaubien; M G Mattei; Claude Lazure; Majambu Mbikay; Michel Chrétien
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.
Molecular endocrinology (Baltimore, Md.) 1991;5(1):111-22.
1991: M Chretien; L Gasper; Suzanne Benjannet; Majambu Mbikay; Claude Lazure; Nabil G Seidah
The Jeremiah Metzger Lecture. From POMC to functional diversity of neural peptides: the key importance of convertases.
Transactions of the American Clinical and Climatological Association 1991;102():195-224.
1991: Nabil G Seidah; R Day; Mieczyslaw Marcinkiewicz; Suzanne Benjannet; Michel Chrétien
Mammalian neural and endocrine pro-protein and pro-hormone convertases belonging to the subtilisin family of serine proteinases.
Enzyme 1991;45(5-6):271-84.
1989: J Paquin; Suzanne Benjannet; N Sawyer; Claude Lazure; Michel Chrétien; Nabil G Seidah
Rat plasma kallikrein: purification, NH2-terminal sequencing and development of a specific radioimmunoassay.
Biochimica et biophysica acta 1989;999(2):103-10.
1989: F Gilbert; J S Chan; Suzanne Benjannet; Nabil G Seidah; P Nadeau; André Duranceau; E Lafontaine; R Beaulieu; Michel Chrétien
Value of plasma NH2-terminal fragment of pro-opiomelanocortin in marking human lung cancer in various clinical settings.
Clinical and investigative medicine. Médecine clinique et experimentale 1989;12(5):285-91.
1988: C G Linard; Majambu Mbikay; Suzanne Benjannet; C Lazure; Nabil G Seidah; M Chrétien
Correct processing and secretion of a human prostatic secretory protein (PSP94) in Escherichia coli.
Gene 1988;73(2):479-87.
1988: Mieczyslaw Marcinkiewicz; R Fischer-Colbrie; Jean-Pierre Falgueyret; Suzanne Benjannet; Nabil G Seidah; Claude Lazure; H Winkler; Michel Chrétien
Two-dimensional immunoblotting analysis and immunocytochemical localization of the secretory polypeptide 7B2 in adrenal medulla.
Neuroscience letters 1988;95(1-3):81-7.
1988: Mieczyslaw Marcinkiewicz; Suzanne Benjannet; Jean-Pierre Falgueyret; Nabil G Seidah; W Schürch; M Verdy; M Cantin; Michel Chrétien
Identification and localization of 7B2 protein in human, porcine, and rat thyroid gland and in human medullary carcinoma.
Endocrinology 1988;123(2):866-73.
1988: Suzanne Benjannet; Mieczyslaw Marcinkiewicz; Jean-Pierre Falgueyret; D E Johnson; Nabil G Seidah; Michel Chrétien
Secretory protein 7B2 is associated with pancreatic hormones within normal islets and some experimentally induced tumors.
Endocrinology 1988;123(2):874-84.
1988: Nabil G Seidah; J Paquin; Josée Hamelin; Suzanne Benjannet; M Chretien
Structural and immunological homology of human and porcine pituitary and plasma IRCM-serine protease 1 to plasma kallikrein: marked selectivity for pairs of basic residues suggests a widespread role in pro-hormone and pro-enzyme processing.
Biochimie 1988;70(1):33-46.
1987: Suzanne Benjannet; R Leduc; N Adrouche; Jean-Pierre Falgueyret; Mieczyslaw Marcinkiewicz; Nabil G Seidah; Majambu Mbikay; Claude Lazure; M Chretien
Chromogranin B (secretogranin I), a putative precursor of two novel pituitary peptides through processing at paired basic residues.
FEBS letters 1987;224(1):142-8.
1987: M Marcinkiewicz; Suzanne Benjannet; N G Seidah; M Cantin; M Chrétien
The pituitary polypeptide "7B2" is associated with LH/FSH and TSH cells and is localized within secretory vesicles.
Cell and tissue research 1987;250(1):205-14.
1987: Jean-Pierre Falgueyret; Mieczyslaw Marcinkiewicz; Suzanne Benjannet; M Cantin; Nabil G Seidah; Michel Chrétien
Immunocytochemical localization of a novel pituitary polypeptide "7B2" in the gastro-intestinal tract of the rat.
Cell and tissue research 1987;249(3):707-9.
1987: F Gilbert; W Walop; J S Chan; Suzanne Benjannet; Nabil G Seidah; W O Spitzer; Michel Chrétien
The role of the NH2-terminal portion of pro-opiomelanocortin as a biomarker for human lung cancer.
Clinical and investigative medicine. Médecine clinique et experimentale 1987;10(5):372-6.
1987: Majambu Mbikay; S Nolet; S Fournier; Suzanne Benjannet; P Chapdelaine; G Paradis; JY Dubé; R Tremblay; C Lazure; N G Seidah
Molecular cloning and sequence of the cDNA for a 94-amino-acid seminal plasma protein secreted by the human prostate.
DNA (Mary Ann Liebert, Inc.) 1987;6(1):23-9.
1985: M Marcinkiewicz; Suzanne Benjannet; N G Seidah; M Cantin; M Chrétien
Immunocytochemical localization of a novel pituitary protein (7B2) within the rat brain and hypophysis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1985;33(12):1219-26.
1985: Mieczyslaw Marcinkiewicz; Suzanne Benjannet; R A Sikstrom; M Cantin; Nabil G Seidah; M Chretien
Immunoreactivity of vasopressin and a novel pituitary protein '7B2' in Long-Evans and Brattleboro rat hypothalamus and hypophysis.
Neuroscience letters 1985;60(1):7-12.
1985: Suzanne Benjannet; R Leduc; Claude Lazure; Nabil G Seidah; Mieczyslaw Marcinkiewicz; Michel Chrétien
GAWK, a novel human pituitary polypeptide: isolation, immunocytochemical localization and complete amino acid sequence.
Biochemical and biophysical research communications 1985;126(1):602-9.
1981: Nabil G Seidah; J Rochemont; Josée Hamelin; Suzanne Benjannet; Michel Chrétien
The missing fragment of the pro-sequence of human pro-opiomelanocortin: sequence and evidence for C-terminal amidation.
Biochemical and biophysical research communications 1981;102(2):710-6.
1980: Nabil G Seidah; Suzanne Benjannet; R Routhier; G De Serres; J Rochemont; M Lis; Michel Chrétien
Purification and characterization of the N-terminal fragment of pro-opiomelanocortin from human pituitaries: homology to the bovine sequence.
Biochemical and biophysical research communications 1980;95(4):1417-24.