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Kazunori Ohnishi

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Satoki Nakamura; Aya Asahina; Shinya Fujisawa; Yasuyuki Nagata; Kiyoshi Shibata; Tomonari Takemura; Lin Tan; Tomohiro Yagyu; Daisuke Yokota; Kazunori Ohnishi
JmjC-domain containing histone demethylase 1B-mediated p15(Ink4b) suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia.
Takafumi Naito; Kazunori Ohnishi; Masaki Tashiro; Keisuke Yamamoto; Yoshiyuki Kagawa; Junichi Kawakami
Impact of cachexia on pharmacokinetic disposition of and clinical responses to oxycodone in cancer patients.
Katsuhito Hori; Kazunori Ohnishi; Kasumi Yamakawa; Naoko Yoshida; Junichi Kawakami
Detection of fluoroquinolone-induced tendon disorders using a hospital database in Japan.

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2013: Satoki Nakamura; Aya Asahina; Shinya Fujisawa; Yasuyuki Nagata; Kiyoshi Shibata; Tomonari Takemura; Lin Tan; Tomohiro Yagyu; Daisuke Yokota; Kazunori Ohnishi
JmjC-domain containing histone demethylase 1B-mediated p15(Ink4b) suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia.
Molecular carcinogenesis 2013;52(1):57-69.
2012: Takafumi Naito; Kazunori Ohnishi; Masaki Tashiro; Keisuke Yamamoto; Yoshiyuki Kagawa; Junichi Kawakami
Impact of cachexia on pharmacokinetic disposition of and clinical responses to oxycodone in cancer patients.
European journal of clinical pharmacology 2012;68(10):1411-8.
2012: Katsuhito Hori; Kazunori Ohnishi; Kasumi Yamakawa; Naoko Yoshida; Junichi Kawakami
Detection of fluoroquinolone-induced tendon disorders using a hospital database in Japan.
Pharmacoepidemiology and drug safety 2012;21(8):886-9.
2012: Kazunori Ohnishi; Shigeki Ohtake; Jin Takeuchi; Tetsuzo Tauchi; Noriko Usui; Fumiharu Yagasaki; Hirohito Yamazaki; Shin Fujisawa; Kiyotoshi Imai; Hitoshi Kiyoi; Yasuhiro Maeda; Koichi Miyamura; Yasushi Miyazaki; Naoki Mori; Tadashi Nagai; Chiaki Nakaseko; Tomoki Naoe
Long-term outcome following imatinib therapy for chronic myelogenous leukemia, with assessment of dosage and blood levels: the JALSG CML202 study.
Cancer science 2012;103(6):1071-8.
2012: Kazunori Ohnishi
[Molecular pathogenesis and treatment of CML in accelerated phase and blast crisis].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 2():309-13.
2012: Makoto Sano; Masao Saotome; Hiroshi Satoh; Tsuyoshi Urushida; Hideki Katoh; Kazunori Ohnishi; Hideharu Hayashi
Pulmonary arterial hypertension caused by treatment with dasatinib for chronic myeloid leukemia -critical alert-.
Internal medicine (Tokyo, Japan) 2012;51(17):2337-40.
2012: Masashi Miwa; Yasuyuki Nagata; Satoki Nakamura; Kazunori Ohnishi; Masafumi Ono; Yukitoshi Sakao; Kazuyuki Shigeno; Hiroyuki Suzuki; Hideo Yasuda; Tomoyuki Fujikura; Sayaka Ishigaki; Akihiko Kato; Yoshihide Fujigaki
Recovery of kidney function by rituximab-based therapy in a patient with Waldenström's macroglobulinemia-related nephropathy presenting cast nephropathy and interstitial lymphocytic infiltration.
Internal medicine (Tokyo, Japan) 2012;51(13):1725-30.
2012: Shinya Motohashi; Kazunori Ohnishi; Takaaki Ono; Katsuhito Hori; Junichi Kawakami
[Comparison of 1 mg/body and 3 mg/body of intravenous granisetron for the prevention of chemotherapy-induced nausea and vomiting and adverse events in hematological malignancy patients].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2012;132(5):675-81.
2011: Takafumi Naito; Kazunori Ohnishi; Yoshiaki Takashina; Masaki Tashiro; Keisuke Yamamoto; Yoshiyuki Kagawa; Junichi Kawakami
CYP3A5*3 affects plasma disposition of noroxycodone and dose escalation in cancer patients receiving oxycodone.
Journal of clinical pharmacology 2011;51(11):1529-38.
2011: Takaaki Ono; Shuichi Miyawaki; Fumihiko Kimura; Heiwa Kanamori; Shigeki Ohtake; Kunio Kitamura; Hiroyuki Fujita; Isamu Sugiura; Kensuke Usuki; Nobuhiko Emi; Shigehisa Tamaki; Yasutaka Aoyama; Hiroyasu Kaya; Tomoki Naoe; Kenichi Tadokoro; Toshikazu Yamaguchi; Ryuzo Ohno; Kazunori Ohnishi
BCR-ABL1 mutations in patients with imatinib-resistant Philadelphia chromosome-positive leukemia by use of the PCR-Invader assay.
Leukemia research 2011;35(5):598-603.
2011: Satoki Nakamura; Kazunori Ohnishi; Kiyoshi Shibata; Tomonari Takemura; Lin Tan; Yasutaka Tanaka; Mitsuo Toda; Kenji Tsunekawa; Manabu Yamada; Mayumi Yamaoka; Junko Yamashita; Michio Fujie; Shinya Fujisawa; Reiko Makita; Yasuyuki Nagata; Mitsuji Yamashita
Transcriptional repression of Cdc25B by IER5 inhibits the proliferation of leukemic progenitor cells through NF-YB and p300 in acute myeloid leukemia.
PloS one 2011;6(11):e28011.
2010: Satoki Nakamura; Mitsuji Yamashita; Daisuke Yokota; Isao Hirano; Takaaki Ono; Michio Fujie; Kiyoshi Shibata; Taishi Niimi; Takuya Suyama; Kasthuraiah Maddali; Kazuhide Asai; Junko Yamashita; Yukiko Iguchi; Kazunori Ohnishi
Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity.
Investigational new drugs 2010;28(4):381-91.
2010: Keiji Matsumoto; Takafumi Naito; Katsuhito Hori; Naoya Suzuki; Yasunori Miyamoto; Yoshiaki Takashina; Kazunori Ohnishi; Junichi Kawakami
Surveillance of workplace contamination and occupational exposure to antineoplastic agents in a hospital setting: establishment of a monitoring method using Doxorubicin.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010;130(3):431-9.
2009: Kayoko Minakata; Kazunori Ohnishi; Satoki Nakamura; Masako Suzuki; Osamu Suzuki
Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(25):2624-9.
2009: Akihiro Takeshita; N Yamakage; Kaori Shinjo; T Ono; I Hirano; Satoshi Nakamura; Kazuyuki Shigeno; Tadasu Tobita; Masato Maekawa; H Kiyoi; Tomoki Naoe; Kazunori Ohnishi; Y Sugimoto; Ryuzo Ohno
CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells.
Leukemia 2009;23(7):1329-36.
2009: Akihiro Takeshita; Kaori Shinjo; Nozomi Yamakage; Takaaki Ono; Isao Hirano; Hirotaka Matsui; Kazuyuki Shigeno; Satoki Nakamura; Tadasu Tobita; Masato Maekawa; Kazunori Ohnishi; Yoshikazu Sugimoto; Hitoshi Kiyoi; Tomoki Naoe; Ryuzo Ohno
CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma.
British journal of haematology 2009;146(1):34-43.
2008: Satoki Nakamura; Keiji Okinaka; Isao Hirano; Takaaki Ono; Yuya Sugimoto; Kazuyuki Shigeno; Shinya Fujisawa; Kaori Shinjo; Kazunori Ohnishi
KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells.
Leukemia research 2008;32(9):1358-65.
2008: Yuya Sugimoto; Satoki Nakamura; Keiji Okinaka; Isao Hirano; Takaaki Ono; Kazuyuki Shigeno; Kaori Shinjo; Kazunori Ohnishi
HOXA10 expression induced by Abl kinase inhibitors enhanced apoptosis through PI3K pathway in CML cells.
Leukemia research 2008;32(6):962-71.
2007: Kazunori Ohnishi
[An advance in the treatment of CML].
Gan to kagaku ryoho. Cancer & chemotherapy 2007;34(13):2185-90.
2007: Kazunori Ohnishi
PML-RARalpha inhibitors (ATRA, tamibaroten, arsenic troxide) for acute promyelocytic leukemia.
International journal of clinical oncology 2007;12(5):313-7.
2007: Tomoyuki Fujisawa; Takafumi Suda; Shun Matsuura; Noriyuki Enomoto; Kaori Takeshita; Kazunori Ohnishi; Kingo Chida
Peripheral T-cell lymphoma with diffuse pulmonary infiltration and an increase in serum KL-6 level.
Respirology (Carlton, Vic.) 2007;12(3):452-4.
2007: Shinya Fujisawa; Ryuzo Ohno; Kazuyuki Shigeno; Naohi Sahara; Satoki Nakamura; Kensuke Naito; Miki Kobayashi; Kaori Shinjo; Akihiro Takeshita; Yoshinari Suzuki; Hisakuni Hashimoto; Kenji Kinoshita; Masahito Shimoya; Toshikazu Kaise; Kazunori Ohnishi
Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide.
Cancer chemotherapy and pharmacology 2007;59(4):485-93.
2007: Kazunori Ohnishi
[The management of chronic phase CML].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 1():499-504.
2006: Keisuke Yamazaki; Hajime Terada; Hiroshi Satoh; Kensuke Naito; Akihiro Takeshita; Akihiko Uehara; Hideki Katoh; Kazunori Ohnishi; Hideharu Hayashi
Arrhythmogenic effects of arsenic trioxide in patients with acute promyelocytic leukemia and an electrophysiological study in isolated guinea pig papillary muscles.
Circulation journal : official journal of the Japanese Circulation Society 2006;70(11):1407-14.
2006: Naohi Sahara; Kazunori Ohnishi; Takaaki Ono; Yuya Sugimoto; Miki Kobayashi; Kaori Takeshita; Kazuyuki Shigeno; Satoki Nakamura; Kensuke Naito; Sadahiro Tamashima; Kenji Nara; Tadasu Tobita; Akihiro Takeshita; Ryuzo Ohno
Clinicopathological and prognostic characteristics of CD33-positive multiple myeloma.
European journal of haematology 2006;77(1):14-8.
2006: Naohi Sahara; Akihiro Takeshita; Takaaki Ono; Yuya Sugimoto; Miki Kobayashi; Kazuyuki Shigeno; Satoki Nakamura; Kaori Shinjo; Kensuke Naito; Kiyoshi Shibata; Takemi Otsuki; Hideharu Hayashi; Kazunori Ohnishi
Role for interleukin-6 and insulin-like growth factor-I via PI3-K/Akt pathway in the proliferation of CD56- and CD56+ multiple myeloma cells.
Experimental hematology 2006;34(6):736-44.
2006: Kensuke Naito; Miki Kobayashi; Naohi Sahara; Kazuyuki Shigeno; Satoki Nakamura; Kaori Shinjo; Tadasu Tobita; Akihiro Takeshita; Ryuzo Ohno; Kazunori Ohnishi
Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy.
International journal of hematology 2006;83(4):318-23.
2006: Satoki Nakamura; Miki Kobayashi; Kiyoshi Shibata; Naohi Sahara; Kazuyuki Shigeno; Kaori Shinjo; Kensuke Naito; Hideharu Hayashi; Kazunori Ohnishi
Etodolac induces apoptosis and inhibits cell adhesion to bone marrow stromal cells in human myeloma cells.
Leukemia research 2006;30(2):123-35.
2005: Akihiro Takeshita; Kaori Shinjo; Kensuke Naito; Hirotaka Matsui; Naohi Sahara; Kazuyuki Shigeno; Taeko Suzumura; Toshinobu Horii; Naohito Shirai; Masato Maekawa; Yoshihiro Yada; Hirofumi Teshima; Jin Takeuchi; Kazunori Ohnishi; Ryuzo Ohno
Two patients with all-trans retinoic acid-resistant acute promyelocytic leukemia treated successfully with gemtuzumab ozogamicin as a single agent.
International journal of hematology 2005;82(5):445-8.
2005: Kazuyuki Shigeno; Kensuke Naito; Naohi Sahara; Miki Kobayashi; Satoki Nakamura; Sinya Fujisawa; Kaori Shinjo; Akihiro Takeshita; Ryuzo Ohno; Kazunori Ohnishi
Arsenic trioxide therapy in relapsed or refractory Japanese patients with acute promyelocytic leukemia: updated outcomes of the phase II study and postremission therapies.
International journal of hematology 2005;82(3):224-9.
2005: Masanori Sakakima; Yoshihide Fujigaki; Takayuki Tsuji; Hirotaka Fukasawa; Takehiko Miyaji; Kensuke Naito; Tatsuo Yamamoto; Katsuhiko Yonemura; Kazunori Ohnishi; Akira Hishida
High dose chemotherapy and stem cell support in a patient of light- and heavy-chain deposition disease with abnormal marrow cell surface antigens and no monoclonal protein.
Internal medicine (Tokyo, Japan) 2005;44(9):970-4.
2005: Miki Kobayashi; Satoki Nakamura; Kiyoshi Shibata; Naohi Sahara; Kazuyuki Shigeno; Kaori Shinjo; Kensuke Naito; Kazunori Ohnishi
Etodolac inhibits EBER expression and induces Bcl-2-regulated apoptosis in Burkitt's lymphoma cells.
European journal of haematology 2005;75(3):212-20.
2005: Kaori Shinjo; Akihiro Takeshita; Naohi Sahara; Miki Kobayashi; Satoki Nakamura; Kazuyuki Shigeno; Kensuke Naito; Masato Maekawa; Kazunori Ohnishi; Ryuzo Ohno
Delayed recovery of normal hematopoiesis in arsenic trioxide treatment of acute promyelocytic leukemia: a comparison to all-trans retinoic acid treatment.
Internal medicine (Tokyo, Japan) 2005;44(8):818-24.
2005: Akihiro Takeshita; Kaori Shinjo; Kensuke Naito; Hirotaka Matsui; Naohi Sahara; Kazuyuki Shigeno; Toshinobu Horii; Naohito Shirai; Masato Maekawa; Kazunori Ohnishi; Tomoki Naoe; Ryuzo Ohno
Efficacy of gemtuzumab ozogamicin on ATRA- and arsenic-resistant acute promyelocytic leukemia (APL) cells.
Leukemia 2005;19(8):1306-11.
2005: Kensuke Naito; Kazunori Ohnishi
[Current and new therapeutic strategies in acute myeloid leukemia].
Gan to kagaku ryoho. Cancer & chemotherapy 2005;32(3):292-6.
2004: Satoki Nakamura; Reiko Nakamura; Kiyoshi Shibata; Miki Kobayashi; Naohi Sahara; Kazuyuki Shigeno; Kaori Shinjo; Kensuke Naito; Kazunori Ohnishi; Noriyuki Kasahara; Yuichi Iwaki
Development of packaging cell lines for generation of adeno-associated virus vectors by lentiviral gene transfer of trans-complementary components.
European journal of haematology 2004;73(4):285-94.
2004: Kazuyuki Shigeno; Hitoshi Yoshida; Ling Pan; Jian-Min Luo; Shinya Fujisawa; Kensuke Naito; Satoki Nakamura; Kaori Shinjo; Akihiro Takeshita; Ryuzo Ohno; Kazunori Ohnishi
Disease-related potential of mutations in transcriptional cofactors CREB-binding protein and p300 in leukemias.
Cancer letters 2004;213(1):11-20.
2004: Akihiro Takeshita; Kensuke Naito; Kaori Shinjo; Naohi Sahara; Hirotaka Matsui; Kazunori Ohnishi; Hiroki Beppu; Kaori Ohtsubo; Toshinobu Horii; Masato Maekawa; Toshiya Inaba; Ryuzo Ohno
Deletion 6p23 and add(11)(p15) leading to NUP98 translocation in a case of therapy-related atypical chronic myelocytic leukemia transforming to acute myelocytic leukemia.
Cancer genetics and cytogenetics 2004;152(1):56-60.
2004: Naohi Sahara; Akihiro Takeshita; Miki Kobayashi; Kazuyuki Shigeno; Satoki Nakamura; Kaori Shinjo; Kensuke Naito; Masato Maekawa; Toshinobu Horii; Kazunori Ohnishi; Kunio Kitamura; Tomoki Naoe; Hideharu Hayash; Ryuzo Ohno
Phenylarsine oxide (PAO) more intensely induces apoptosis in acute promyelocytic leukemia and As2O3-resistant APL cell lines than As2O3 by activating the mitochondrial pathway.
Leukemia & lymphoma 2004;45(5):987-95.
2004: Kazunori Ohnishi; Akio Ino; Yuji Kishimoto; Noriko Usui; Chihiro Shimazaki; Shigeki Ohtake; Hirokuni Taguchi; Fumiharu Yagasaki; Masao Tomonaga; Tomomitsu Hotta; Ryuzo Ohno
Multicenter prospective study of interferon alpha versus allogeneic stem cell transplantation for patients with new diagnoses of chronic myelogenous leukemia.
International journal of hematology 2004;79(4):345-53.
2003: Jian-Min Luo; H Yoshida; S Komura; N Ohishi; Ling Pan; Kazuyuki Shigeno; I Hanamura; K Miura; S Iida; R Ueda; Tomoki Naoe; Y Akao; Ryuzo Ohno; Kazunori Ohnishi
Possible dominant-negative mutation of the SHIP gene in acute myeloid leukemia.
Leukemia 2003;17(1):1-8.
2002: Naohi Sahara; Akihiro Takeshita; Kazuyuki Shigeno; Shinya Fujisawa; Kaori Takeshita; Kensuke Naito; Michio Ihara; Takaaki Ono; Sadahiro Tamashima; Kenji Nara; Kazunori Ohnishi; Ryuzo Ohno
Clinicopathological and prognostic characteristics of CD56-negative multiple myeloma.
British journal of haematology 2002;117(4):882-5.
2002: Hirotaka Matsui; Akihiro Takeshita; Kensuke Naito; Kaori Shinjo; Kazuyuki Shigeno; Masato Maekawa; Y Yamakawa; M Tanimoto; Miki Kobayashi; Kazunori Ohnishi; Ryuzo Ohno
Reduced effect of gemtuzumab ozogamicin (CMA-676) on P-glycoprotein and/or CD34-positive leukemia cells and its restoration by multidrug resistance modifiers.
Leukemia 2002;16(5):813-9.
2002: Kazunori Ohnishi; H Yoshida; Kazuyuki Shigeno; Satoshi Nakamura; Shinya Fujisawa; Kensuke Naito; Kaori Shinjo; fujita yohta; Hirotaka Matsui; Naohi Sahara; Akihiro Takeshita; Hiroshi Satoh; Hajime Terada; Ryuzo Ohno
Arsenic trioxide therapy for relapsed or refractory Japanese patients with acute promyelocytic leukemia: need for careful electrocardiogram monitoring.
Leukemia 2002;16(4):617-22.
2002: Akihiro Takeshita; Kaori Shinjo; Kensuke Naito; Kazunori Ohnishi; Masato Higuchi; Ryuzo Ohno
Erythropoietin receptor in myelodysplastic syndrome and leukemia.
Leukemia & lymphoma 2002;43(2):261-4.
2002: Kaori Shinjo; Akihiro Takeshita; Mitsuaki Yanagi; Kazuko Yokota; Kazumi Hirano; Mieko Suzuki; Kazunori Ohnishi; Ryuzo Ohno
Efficacy of the Shinki bioclean room for preventing infection in neutropenic patients.
Journal of advanced nursing 2002;37(3):227-33.
2001: Kazunori Ohnishi
[Chronic myelogenous leukemia].
Gan to kagaku ryoho. Cancer & chemotherapy 2001;28(9):1199-205.
2001: Akihiro Takeshita; Kazuyuki Shigeno; Kaori Shinjo; Kensuke Naito; Kazunori Ohnishi; Hideharu Hayashi; M Tanimoto; Ryuzo Ohno
All-trans retinoic acid (ATRA) differentiates acute promyelocytic leukemia cells independently of P-glycoprotein (P-gp) related multidrug resistance.
Leukemia & lymphoma 2001;42(4):739-46.
2001: Kazunori Ohnishi; T Ino; Y Kishimoto; N Usui; C Shimazaki; S Ohtake; H Taguchi; S Kusumoto; Kazutaka Kuriyama; T Hotta; Ryuzo Ohno
Multicenter prospective study of interferon-alpha versus bone marrow transplantation for newly diagnosed patients with chronic myelogenous leukemia: a preliminary analysis.
Cancer chemotherapy and pharmacology 2001;48 Suppl 1():S59-64.
2001: M Izumi; Akihiro Takeshita; Kaori Shinjo; Kensuke Naito; H Matsui; Kiyoshi Shibata; Kazunori Ohnishi; T Kanno; Ryuzo Ohno
Decreased amount of mpl and reduced expression of glycoprotein IIb/IIIa and glycoprotein Ib on platelets from patients with refractory anemia: analysis by a non-isotopic quantitative ligand binding assay and immunofluorescence.
European journal of haematology 2001;66(4):245-52.
2000: Kazunori Ohnishi; H Yoshida; Kazuyuki Shigeno; Satoshi Nakamura; Shinya Fujisawa; Kensuke Naito; Kaori Shinjo; fujita yohta; Hirotaka Matsui; Akihiro Takeshita; S Sugiyama; Hiroshi Satoh; Hajime Terada; Ryuzo Ohno
Prolongation of the QT interval and ventricular tachycardia in patients treated with arsenic trioxide for acute promyelocytic leukemia.
Annals of internal medicine 2000;133(11):881-5.
2000: Kaori Shinjo; Akihiro Takeshita; Kazunori Ohnishi; T Sakura; Shuichi Miyawaki; A Hiraoka; M Takeuchi; S Tomoyasu; H Wakita; K Ata; H Fukutani; R Ueda; Ryuzo Ohno
Good prognosis of patients with acute promyelocytic leukemia who achieved second complete remission (CR) with a new retinoid, Am80, after relapse from CR induced by all-trans-retinoic acid.
International journal of hematology 2000;72(4):470-3.
2000: Ling Pan; Kazunori Ohnishi; W J Zhang; H Yoshida; Lola Maksumova; Farkhad Muratkhodjaev; Kazuyuki Shigeno; Satoshi Nakamura; Jian-Min Luo; Hong-Ling Hao; Shinya Fujisawa; Kensuke Naito; Kaori Shinjo; Akihiro Takeshita; Ryuzo Ohno
In vitro IL-12 treatment of peripheral blood mononuclear cells from patients with leukemia or myelodysplastic syndromes: increase in cytotoxicity and reduction in WT1 gene expression.
Leukemia 2000;14(9):1634-41.
2000: Kazunori Ohnishi; S Minami; T Ueda; M Nishimura; K Tsubaki; Y Takemoto; Akihiro Takeshita; H Sao; S Kageyama; R Ueda; Ryuzo Ohno
Multicenter prospective study of interferon-alpha and conventional chemotherapy versus bone marrow transplantation for newly diagnosed patients with chronic myelogenous leukemia. Kouseisho Leukemia Study Group.
International journal of hematology 2000;72(2):229-36.
2000: Lola Maksumova; Kazunori Ohnishi; Farkhad Muratkhodjaev; W Zhang; Ling Pan; Akihiro Takeshita; Ryuzo Ohno
Increased sensitivity of multidrug-resistant myeloid leukemia cell lines to lovastatin.
Leukemia 2000;14(8):1444-50.
2000: Kensuke Naito; Akihiro Takeshita; Kazuyuki Shigeno; Satoshi Nakamura; Shinya Fujisawa; Kaori Shinjo; H Yoshida; Kazunori Ohnishi; M Mori; Susumu Terakawa; Ryuzo Ohno
Calicheamicin-conjugated humanized anti-CD33 monoclonal antibody (gemtuzumab zogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemia cell lines, but is inactive on P-glycoprotein-expressing sublines.
Leukemia 2000;14(8):1436-43.
2000: Satoshi Nakamura; Kazunori Ohnishi; H Yoshida; Kaori Shinjo; Akihiro Takeshita; K Tohyama; Ryuzo Ohno; Y Koide
Retrovirus-mediated gene transfer of granulocyte colony-stimulating factor receptor (G-CSFR) cDNA into MDS cells and induction of their differentiation by G-CSF.
Cytokines, cellular & molecular therapy 2000;6(2):61-70.
2000: W J Zhang; Kazunori Ohnishi; H Yoshida; Ling Pan; Lola Maksumova; Farkhad Muratkhodjaev; Jian-Min Luo; Kazuyuki Shigeno; Shinya Fujisawa; Kensuke Naito; Satoshi Nakamura; Kaori Shinjo; Akihiro Takeshita; Ryuzo Ohno
Spicamycin and KRN5500 induce apoptosis in myeloid and lymphoid cell lines with down-regulation of bcl-2 expression and modulation of promyelocytic leukemia protein.
Japanese journal of cancer research : Gann 2000;91(6):604-11.
2000: Kazunori Ohnishi
[Clinicopathological characteristics of Burkitt lymphoma].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(3):635-8.
2000: Kazunori Ohnishi
Current trends in the management of malignant lymphoma: new WHO classification, guidelines for high-dose therapy with HSCT, and new response criteria.
International journal of clinical oncology 2000;5(1):1-7.
2000: Akihiro Takeshita; Kaori Shinjo; Kensuke Naito; Kazunori Ohnishi; Y Sugimoto; Y Yamakawa; M Tanimoto; K Kitamura; Tomoki Naoe; Ryuzo Ohno
Role of P-glycoprotein in all-trans retinoic acid (ATRA) resistance in acute promyelocytic leukaemia cells: analysis of intracellular concentration of ATRA.
British journal of haematology 2000;108(1):90-2.
1999: Akihiro Takeshita; Kaori Shinjo; M Yamashita; Shinya Fujisawa; Kensuke Naito; Kazunori Ohnishi; K Takahashi; Hirotaka Matsui; Ryuzo Ohno
Extensive cytogenetic studies of clonality following interferon-alpha therapy in chronic myeloid leukemia occurring in monosomic cells in a patient with Turner syndrome mosaic.
Leukemia 1999;13(11):1749-53.
1999: Mitsuaki Yanagi; Kaori Shinjo; Akihiro Takeshita; Tadasu Tobita; K Yano; Miki Kobayashi; H Terasaki; Tomoki Naoe; Kazunori Ohnishi; Ryuzo Ohno
Simple and reliably sensitive diagnosis and monitoring of Philadelphia chromosome-positive cells in chronic myeloid leukemia by interphase fluorescence in situ hybridization of peripheral blood cells.
Leukemia 1999;13(4):542-52.
1999: Kazunori Ohnishi
[Oral antitumor drugs for hematological malignancies].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(3):295-300.
1998: Kazunori Ohnishi; Ryuzo Ohno
[New antitumor drugs for non-Hodgkin's lymphoma].
Gan to kagaku ryoho. Cancer & chemotherapy 1998;25(14):2223-8.
1998: Kazunori Ohnishi; Tadasu Tobita; K Sinjo; Akihiro Takeshita; Ryuzo Ohno
Modulation of homeobox B6 and B9 genes expression in human leukemia cell lines during myelomonocytic differentiation.
Leukemia & lymphoma 1998;31(5-6):599-608.
1998: W Zhang; Kazunori Ohnishi; Kazuyuki Shigeno; Shinya Fujisawa; Kensuke Naito; Satoshi Nakamura; K Takeshita; Akihiro Takeshita; Ryuzo Ohno
The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms.
Leukemia 1998;12(9):1383-91.
1998: Kazunori Ohnishi; M Tomonaga; N Kamada; K Onozawa; A Kuramoto; Hiroo Dohy; H Mizoguchi; Shuichi Miyawaki; K Tsubaki; Y Miura; Mitsuhiro Omine; T Kobayashi; Tomoki Naoe; T Ohshima; Kunitake Hirashima; S Ohtake; I Takahashi; Y Morishima; Kensuke Naito; Norio Asou; M Tanimoto; A Sakuma; Ryuzo Ohno
A long term follow-up of a randomized trial comparing interferon-alpha with busulfan for chronic myelogenous leukemia. The Kouseisho Leukemia Study Group.
Leukemia research 1998;22(9):779-86.
1998: Kaori Shinjo; Akihiro Takeshita; Satoshi Nakamura; Kenichi Naitoh; Mitsuaki Yanagi; Tadasu Tobita; Kazunori Ohnishi; Ryuzo Ohno
Serum thrombopoietin levels in patients correlate inversely with platelet counts during chemotherapy-induced thrombocytopenia.
Leukemia 1998;12(3):295-300.
1998: Akihiro Takeshita; Kaori Shinjo; M Izumi; P Ling; Satoshi Nakamura; Kensuke Naito; Kazunori Ohnishi; Ryuzo Ohno
Quantitative expression of thrombopoietin receptor on leukaemia cells from patients with acute myeloid leukaemia and acute lymphoblastic leukaemia.
British journal of haematology 1998;100(2):283-90.
1998: Kazunori Ohnishi; H Yamanishi; Kensuke Naito; M Utsumi; S Yokomaku; N Hirabayashi; Ryuzo Ohno
Reconstitution of peripheral blood lymphocyte subsets in the long-term disease-free survivors of patients with acute myeloblastic leukemia.
Leukemia 1998;12(1):52-8.
1997: Akihiro Takeshita; Kaori Shinjo; Kensuke Naito; Satoshi Nakamura; M Izumi; P Ling; Kazunori Ohnishi; Ryuzo Ohno
Amount of mpl on bone marrow haemopoietic precursor cells from healthy volunteers and patients with refractory anaemia.
British journal of haematology 1997;99(4):746-55.
1997: Tadasu Tobita; Akihiro Takeshita; K Kitamura; Kazunori Ohnishi; Mitsuaki Yanagi; Akira Hiraoka; Takahiro Karasuno; M Takeuchi; Shuichi Miyawaki; R Ueda; Tomoki Naoe; Ryuzo Ohno
Treatment with a new synthetic retinoid, Am80, of acute promyelocytic leukemia relapsed from complete remission induced by all-trans retinoic acid.
Blood 1997;90(3):967-73.
1997: Tadasu Tobita; K Shinjyo; Mitsuaki Yanagi; Akihiro Takeshita; Kazunori Ohnishi; Ryuzo Ohno
Relapse in the external auditory canal of acute promyelocytic leukemia after treatment with all-trans retinoic acid.
Internal medicine (Tokyo, Japan) 1997;36(7):484-6.
1997: Kazunori Ohnishi
[Recent progress in the management of malignant lymphoma].
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24(9):1074-8.
1997: Kaori Shinjo; Akihiro Takeshita; Kazunori Ohnishi; Ryuzo Ohno
Granulocyte colony-stimulating factor receptor at various differentiation stages of normal and leukemic hematopoietic cells.
Leukemia & lymphoma 1997;25(1-2):37-46.
1997: Kaori Shinjo; Akihiro Takeshita; Masato Higuchi; Kazunori Ohnishi; Ryuzo Ohno
Erythropoietin receptor expression on human bone marrow erythroid precursor cells by a newly-devised quantitative flow-cytometric assay.
British journal of haematology 1997;96(3):551-8.
1996: Akihiro Takeshita; Y Shibata; K Shinjo; Mitsuaki Yanagi; Tadasu Tobita; Kazunori Ohnishi; Shuichi Miyawaki; K Shudo; R Ohno
Successful treatment of relapse of acute promyelocytic leukemia with a new synthetic retinoid, Am80.
Annals of internal medicine 1996;124(10):893-6.
1996: Akihiro Takeshita; K Shinjo; Kazunori Ohnishi; R Ohno
Expression of multidrug resistance P-glycoprotein in myeloid progenitor cells of different phenotype: comparison between normal bone marrow cells and leukaemia cells.
British journal of haematology 1996;93(1):18-21.
1995: Akihiro Takeshita; K Shinjo; Kazunori Ohnishi; R Ohno
Allergic reaction involving liver dysfunction and disseminated intravascular coagulation caused by a health food, Proporis.
Internal medicine (Tokyo, Japan) 1995;34(12):1207-9.
1995: K Shinjo; Akihiro Takeshita; Kazunori Ohnishi; R Ohno
Expression of granulocyte colony-stimulating factor receptor increases with differentiation in myeloid cells by a newly-devised quantitative flow-cytometric assay.
British journal of haematology 1995;91(4):783-94.
1995: Kazunori Ohnishi; R Ohno; M Tomonaga; N Kamada; K Onozawa; A Kuramoto; H Dohy; H Mizoguchi; Shuichi Miyawaki; K Tsubaki
A randomized trial comparing interferon-alpha with busulfan for newly diagnosed chronic myelogenous leukemia in chronic phase.
Blood 1995;86(3):906-16.
1995: Akihiro Takeshita; K Shinjo; Kazunori Ohnishi; R Ohno
New flow cytometric method for detection of minimally expressed multidrug resistance P-glycoprotein on normal and acute leukemia cells using biotinylated MRK16 and streptavidin-RED670 conjugate.
Japanese journal of cancer research : Gann 1995;86(6):607-15.
1994: Kazunori Ohnishi; R Ohno
[New antitumor drugs for malignant lymphoma: a review].
Gan to kagaku ryoho. Cancer & chemotherapy 1994;21(8):1157-62.
1994: R Ohno; Kazunori Ohnishi; Akihiro Takeshita; M Tanimoto; H Murakami; A Kanamaru; N Asou; T Kobayashi; K Kuriyama; E Ohmoto
All-trans retinoic acid therapy in relapsed/refractory or newly diagnosed acute promyelocytic leukemia (APL) in Japan.
Leukemia 1994;8 Suppl 3():S64-9.
1993: Kazunori Ohnishi; B Bonavida
Regulation of B-cell lymphoma growth in syngeneic SJL/J mice. establishment of tumor dormancy following administration of anti-CD4 monoclonal antibody into tumor-bearing mice.
Leukemia 1993;7(11):1801-6.