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Kisho Ohtani

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Kaku Nakano; Kensuke Egashira; Kisho Ohtani; Zhao Gang; Eiko Iwata; Miho Miyagawa; Kenji Sunagawa
Azelnidipine has anti-atherosclerotic effects independent of its blood pressure-lowering actions in monkeys and mice.
Kensuke Egashira; Kaku Nakano; Kisho Ohtani; Kouta Funakoshi; Gang Zhao; Yoshiko Ihara; Jun-Ichiro Koga; Satoshi Kimura; Ryuji Tominaga; Kenji Sunagawa
Local delivery of anti-monocyte chemoattractant protein-1 by gene-eluting stents attenuates in-stent stenosis in rabbits and monkeys.
Yoshiko Ihara; Kensuke Egashira; Kaku Nakano; Kisho Ohtani; Mitsuki Kubo; Jun-ichiro Koga; Masaru Iwai; Masatsugu Horiuchi; Zhao Gang; Sho-ichi Yamagishi; Kenji Sunagawa
Upregulation of the ligand-RAGE pathway via the angiotensin II type I receptor is essential in the pathogenesis of diabetic atherosclerosis.

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2008: Kaku Nakano; Kensuke Egashira; Kisho Ohtani; Zhao Gang; Eiko Iwata; Miho Miyagawa; Kenji Sunagawa
Azelnidipine has anti-atherosclerotic effects independent of its blood pressure-lowering actions in monkeys and mice.
Atherosclerosis 2008;196(1):172-9.
2007: Kensuke Egashira; Kaku Nakano; Kisho Ohtani; Kouta Funakoshi; Gang Zhao; Yoshiko Ihara; Jun-Ichiro Koga; Satoshi Kimura; Ryuji Tominaga; Kenji Sunagawa
Local delivery of anti-monocyte chemoattractant protein-1 by gene-eluting stents attenuates in-stent stenosis in rabbits and monkeys.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2563-8.
2007: Yoshiko Ihara; Kensuke Egashira; Kaku Nakano; Kisho Ohtani; Mitsuki Kubo; Jun-ichiro Koga; Masaru Iwai; Masatsugu Horiuchi; Zhao Gang; Sho-ichi Yamagishi; Kenji Sunagawa
Upregulation of the ligand-RAGE pathway via the angiotensin II type I receptor is essential in the pathogenesis of diabetic atherosclerosis.
Journal of molecular and cellular cardiology 2007;43(4):455-64.
2007: Kaku Nakano; Kensuke Egashira; Kisho Ohtani; Gang Zhao; Kouta Funakoshi; Yoshiko Ihara; Kenji Sunagawa
Catheter-based adenovirus-mediated anti-monocyte chemoattractant gene therapy attenuates in-stent neointima formation in cynomolgus monkeys.
Atherosclerosis 2007;194(2):309-16.
2006: Kisho Ohtani; Kensuke Egashira; Kaku Nakano; Gang Zhao; Kouta Funakoshi; Yoshiko Ihara; Satoshi Kimura; Ryuji Tominaga; Ryuichi Morishita; Kenji Sunagawa
Stent-based local delivery of nuclear factor-kappaB decoy attenuates in-stent restenosis in hypercholesterolemic rabbits.
Circulation 2006;114(25):2773-9.
2006: Kisho Ohtani; Kensuke Egashira; Yoshiko Ihara; Kaku Nakano; Kouta Funakoshi; Gang Zhao; Masataka Sata; Kenji Sunagawa
Angiotensin II type 1 receptor blockade attenuates in-stent restenosis by inhibiting inflammation and progenitor cells.
Hypertension 2006;48(4):664-70.
2004: Qingwei Zhao; Kensuke Egashira; Ken-ichi Hiasa; Minako Ishibashi; Shujiro Inoue; Kisho Ohtani; Chunyan Tan; Masabumi Shibuya; Akira Takeshita; Kenji Sunagawa
Essential role of vascular endothelial growth factor and Flt-1 signals in neointimal formation after periadventitial injury.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2284-9.
2004: Minako Ishibashi; Kensuke Egashira; Qingwei Zhao; Ken-ichi Hiasa; Kisho Ohtani; Yoshiko Ihara; Israel F Charo; Shinobu Kura; Teruhisa Tsuzuki; Akira Takeshita; Kenji Sunagawa
Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(11):e174-8.
2004: Kisho Ohtani; Kensuke Egashira; Ken-ichi Hiasa; Qingwei Zhao; Shiro Kitamoto; Minako Ishibashi; Makoto Usui; Shujiro Inoue; Yoshikazu Yonemitsu; Katsuo Sueishi; Masataka Sata; Masabumi Shibuya; Kenji Sunagawa
Blockade of vascular endothelial growth factor suppresses experimental restenosis after intraluminal injury by inhibiting recruitment of monocyte lineage cells.
Circulation 2004;110(16):2444-52.
2004: Kisho Ohtani; Kensuke Egashira
[NO and atherosclerosis].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():544-7.
2004: Kisho Ohtani; Makoto Usui; Kaku Nakano; Yoshiro Kohjimoto; Shunichi Kitajima; Yasuhiko Hirouchi; X-H Li; Shiro Kitamoto; Akira Takeshita; Kensuke Egashira
Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys.
Gene therapy 2004;11(16):1273-82.
2004: Ken-ichi Hiasa; Minako Ishibashi; Kisho Ohtani; Shujiro Inoue; Qingwei Zhao; Shiro Kitamoto; Masataka Sata; Toshihiro Ichiki; Akira Takeshita; Kensuke Egashira
Gene transfer of stromal cell-derived factor-1alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase-related pathway: next-generation chemokine therapy for therapeutic neovascularization.
Circulation 2004;109(20):2454-61.
2004: Minako Ishibashi; Ken-ichi Hiasa; Qingwei Zhao; Shujiro Inoue; Kisho Ohtani; Shiro Kitamoto; Miyuki Tsuchihashi; Takeshi Sugaya; Israel F Charo; Shinobu Kura; Teruhisa Tsuzuki; Tatsuro Ishibashi; Akira Takeshita; Kensuke Egashira
Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling.
Circulation research 2004;94(9):1203-10.
2004: Kisho Ohtani; Kensuke Egashira; Makoto Usui; Minako Ishibashi; Ken-ichi Hiasa; Qingwei Zhao; M Aoki; Yasufumi Kaneda; R Morishita; Akira Takeshita
Inhibition of neointimal hyperplasia after balloon injury by cis-element 'decoy' of early growth response gene-1 in hypercholesterolemic rabbits.
Gene therapy 2004;11(2):126-32.
2002: Makoto Usui; Kensuke Egashira; Kisho Ohtani; Chu Kataoka; Minako Ishibashi; Ken-ichi Hiasa; Makoto Katoh; Qingwei Zhao; Shiro Kitamoto; Akira Takeshita
Anti-monocyte chemoattractant protein-1 gene therapy inhibits restenotic changes (neointimal hyperplasia) after balloon injury in rats and monkeys.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1838-40.
2002: Kensuke Egashira; Qingwei Zhao; Chu Kataoka; Kisho Ohtani; Makoto Usui; Israel F Charo; Ken-Ichi Nishida; Shujiro Inoue; Makoto Katoh; Toshihiro Ichiki; Akira Takeshita
Importance of monocyte chemoattractant protein-1 pathway in neointimal hyperplasia after periarterial injury in mice and monkeys.
Circulation research 2002;90(11):1167-72.
2002: Mayuko Kubo-Inoue; Kensuke Egashira; Makoto Usui; Masao Takemoto; Kisho Ohtani; Makoto Katoh; Hiroaki Shimokawa; Akira Takeshita
Long-term inhibition of nitric oxide synthesis increases arterial thrombogenecity in rat carotid artery.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1478-84.