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Eiko Ohtsuka

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Hiroshi Morioka; Mikiko Kurihara; Hiroyuki Kobayashi; Kousuke Satou; Yasuo Komatsu; Makiyo Uchida; Eiko Ohtsuka; Takuya Torizawa; Koichi Kato; Ichio Shimada; Tsukasa Matsunaga; Osamu Nikaido
DNA-binding properties of the antibody specific for the Dewar photoproduct of thymidylyl-(3-5')-thymidine.
Yuji Yamamoto; Satoshi Shuto; Yutaka Tamura; Tetsuya Kodama; Shuichi Hoshika; Satoshi Ichikawa; Yoshihito Ueno; Eiko Ohtsuka; Yasuo Komatsu; Akira Matsuda
Oligodeoxynucleotides having a loop consisting of 3'-deoxy-4'-C-(2-hydroxyethyl)thymidines form stable hairpins.
Satoshi Shuto; Yutaka Tamura; Yuji Yamamoto; Tetsuya Kodama; Shuichi Hoshika; Satoshi Ichikawa; Yoshihito Ueno; Eiko Ohtsuka; Yasuo Komatsu; Akira Matsuda
Stable hairpins having a loop consisting of 3'-deoxy-4'-C-(2-hydroxyethyl)thymidines.

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All Publications

2006: Hiroshi Morioka; Mikiko Kurihara; Hiroyuki Kobayashi; Kousuke Satou; Yasuo Komatsu; Makiyo Uchida; Eiko Ohtsuka; Takuya Torizawa; Koichi Kato; Ichio Shimada; Tsukasa Matsunaga; Osamu Nikaido
DNA-binding properties of the antibody specific for the Dewar photoproduct of thymidylyl-(3-5')-thymidine.
Nucleosides, nucleotides & nucleic acids 2006;25(4-6):667-79.
2004: Yuji Yamamoto; Satoshi Shuto; Yutaka Tamura; Tetsuya Kodama; Shuichi Hoshika; Satoshi Ichikawa; Yoshihito Ueno; Eiko Ohtsuka; Yasuo Komatsu; Akira Matsuda
Oligodeoxynucleotides having a loop consisting of 3'-deoxy-4'-C-(2-hydroxyethyl)thymidines form stable hairpins.
Biochemistry 2004;43(27):8690-9.
2004: Satoshi Shuto; Yutaka Tamura; Yuji Yamamoto; Tetsuya Kodama; Shuichi Hoshika; Satoshi Ichikawa; Yoshihito Ueno; Eiko Ohtsuka; Yasuo Komatsu; Akira Matsuda
Stable hairpins having a loop consisting of 3'-deoxy-4'-C-(2-hydroxyethyl)thymidines.
Nucleic acids symposium series (2004) 2004;(48):67-8.
2002: Yasuo Komatsu; Kaoru Nobuoka; Naoko Karino-Abe; Akira Matsuda; Eiko Ohtsuka
In vitro selection of hairpin ribozymes activated with short oligonucleotides.
Biochemistry 2002;41(29):9090-8.
2000: Yasuo Komatsu; S Yamashita; N Kazama; Kaoru Nobuoka; Eiko Ohtsuka
Construction of new ribozymes requiring short regulator oligonucleotides as a cofactor.
Journal of molecular biology 2000;299(5):1231-43.
2000: H Yokoyama; Ryuta Mizutani; Yoshinori Satow; Yasuo Komatsu; Eiko Ohtsuka; Osamu Nikaido
Crystal structure of the 64M-2 antibody Fab fragment in complex with a DNA dT(6-4)T photoproduct formed by ultraviolet radiation.
Journal of molecular biology 2000;299(3):711-23.
2000: Yasuo Komatsu; I Kanzaki; M Shirai; I Kumagai; S Yamashita; Eiko Ohtsuka
Functional domain-assembly in hairpin ribozymes.
Journal of biochemistry 2000;127(4):531-6.
2000: Takuya Torizawa; N Yamamoto; Takahiro Suzuki; Kaoru Nobuoka; Yasuo Komatsu; Hiroshi Morioka; Osamu Nikaido; Eiko Ohtsuka; Koichi Kato; Ichio Shimada
DNA binding mode of the Fab fragment of a monoclonal antibody specific for cyclobutane pyrimidine dimer.
Nucleic acids research 2000;28(4):944-51.
2000: H Inoue; T Furukawa; T Tamura; Yasuo Komatsu; Eiko Ohtsuka
Two-terpyridine.Cu(II) complexes-containing antisense systems for rapid and highly site-specific RNA cleavage.
Nucleic acids symposium series 2000;(44):279-80.
1999: Yasuo Komatsu; I Kumagai; Eiko Ohtsuka
Investigation of the recognition of an important uridine in an internal loop of a hairpin ribozyme prepared using post-synthetically modified oligonucleotides.
Nucleic acids research 1999;27(22):4314-23.
1999: Hiroshi Kobayashi; J Kato; Hiroshi Morioka; Jon D Stewart; Eiko Ohtsuka
Tryptophan H33 plays an important role in pyrimidine (6-4) pyrimidone photoproduct binding by a high-affinity antibody.
Protein engineering 1999;12(10):879-84.
1999: Takuya Torizawa; Koichi Kato; Jun-Ya Kato; Hiroshi Kobayashi; Yasuo Komatsu; Hiroshi Morioka; Osamu Nikaido; Eiko Ohtsuka; Ichio Shimada
Conformational multiplicity of the antibody combining site of a monoclonal antibody specific for a (6-4) photoproduct.
Journal of molecular biology 1999;290(3):731-40.
1999: Hiroshi Kobayashi; K Sato; Yasuo Komatsu; Hiroshi Morioka; Jon D Stewart; Toshiki Tsurimoto; Eiko Ohtsuka
Effects of a high-affinity antibody fragment on DNA polymerase reactions near a (6-4) photoproduct site.
Photochemistry and photobiology 1999;69(2):226-30.
1999: Hiroshi Kobayashi; Hiroshi Morioka; K Tobisawa; Takuya Torizawa; Koichi Kato; Ichio Shimada; Osamu Nikaido; Jon D Stewart; Eiko Ohtsuka
Probing the interaction between a high-affinity single-chain Fv and a pyrimidine (6-4) pyrimidone photodimer by site-directed mutagenesis.
Biochemistry 1999;38(2):532-9.
1999: Yasuo Komatsu; S Yamashita; N Kazama; Eiko Ohtsuka
Induction of ribozyme activity by anti-ribozyme oligonucleotides.
Nucleic acids symposium series 1999;(42):279-80.
1999: H Yokoyama; Ryuta Mizutani; Yoshinori Satow; Yasuo Komatsu; Eiko Ohtsuka; Osamu Nikaido
Crystal structures of the 64M-2 and 64M-3 antibody Fabs complexed with DNA (6-4) photoproducts.
Nucleic acids symposium series 1999;(42):267-8.
1999: T Tamura; T Furukawa; Yasuo Komatsu; Eiko Ohtsuka; H Inoue
Toward artificial ribonucleases: design and synthesis of 2'-O-methyloligonucleotides with a terpyridine-copper(II) complex.
Nucleic acids symposium series 1999;(42):109-10.
1999: K Sato; Yasuo Komatsu; Takuya Torizawa; Koichi Kato; Ichio Shimada; Eiko Ohtsuka
Chemical synthesis and properties of (6-4) photoproduct and its analogs.
Nucleic acids symposium series 1999;(42):37-8.
1999: Y Terashima; Masayoshi Fukuoka; Eiko Ohtsuka; H Inoue
Further studies of KMnO4 oxidation of synthetic DNAs containing oxidatively damaged bases.
Nucleic acids symposium series 1999;(42):35-6.
1998: Hiroshi Kobayashi; Hiroshi Morioka; Osamu Nikaido; Jon D Stewart; Eiko Ohtsuka
The role of surface lysines in pyrimidine (6-4) pyrimidone photoproduct binding by a high-affinity antibody.
Protein engineering 1998;11(11):1089-92.
1998: Yasuo Komatsu; M Shirai; Eiko Ohtsuka
Modification and application of self-trimming hairpin ribozymes to targeting a transcribed RNA in vitro.
Journal of biochemistry 1998;124(5):986-91.
1998: S Koizume; H Inoue; Hiroyuki Kamiya; Eiko Ohtsuka
Neighboring base damage induced by permanganate oxidation of 8-oxoguanine in DNA.
Nucleic acids research 1998;26(15):3599-607.
1998: Takuya Torizawa; Koichi Kato; Y Kimura; T Asada; Hiroshi Kobayashi; Yasuo Komatsu; Hiroshi Morioka; Osamu Nikaido; Eiko Ohtsuka; Ichio Shimada
31P NMR study of the interactions between oligodeoxynucleotides containing (6-4) photoproduct and Fab fragments of monoclonal antibodies specific for (6-4) photoproduct.
FEBS letters 1998;429(2):157-61.
1998: Hiroshi Morioka; H Miura; Hiroshi Kobayashi; T Koizumi; K Fujii; K Asano; T Matsunaga; Osamu Nikaido; Jon D Stewart; Eiko Ohtsuka
Antibodies specific for (6-4) DNA photoproducts: cloning, antibody modeling and construction of a single-chain Fv derivative.
Biochimica et biophysica acta 1998;1385(1):17-32.
1998: T Oku; S Ikeda; H Sasaki; K Fukuda; Hiroshi Morioka; Eiko Ohtsuka; H Yoshikawa; Toshiki Tsurimoto
Functional sites of human PCNA which interact with p21 (Cip1/Waf1), DNA polymerase delta and replication factor C.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(6):357-69.
1998: Hiroshi Kobayashi; Hiroshi Morioka; Takuya Torizawa; Koichi Kato; Ichio Shimada; Osamu Nikaido; Eiko Ohtsuka
Specificities and rates of binding of anti-(6-4) photoproduct antibody fragments to synthetic thymine photoproducts.
Journal of biochemistry 1998;123(1):182-8.
1997: Yasuo Komatsu; T Tsujino; Takahiro Suzuki; Osamu Nikaido; Eiko Ohtsuka
Antigen structural requirements for recognition by a cyclobutane thymine dimer-specific monoclonal antibody.
Nucleic acids research 1997;25(19):3889-94.
1997: Yasuo Komatsu; I Kanzaki; M Shirai; Eiko Ohtsuka
A new type of hairpin ribozyme consisting of three domains.
Biochemistry 1997;36(32):9935-40.
1997: Yasuo Komatsu; M Shirai; S Yamashita; Eiko Ohtsuka
Construction of hairpin ribozymes with a three-way junction.
Bioorganic & medicinal chemistry 1997;5(6):1063-9.
1997: T Nishizaki; S Iwai; Eiko Ohtsuka; H Nakamura
Solution structure of an RNA.2'-O-methylated RNA hybrid duplex containing an RNA.DNA hybrid segment at the center.
Biochemistry 1997;36(9):2577-85.
1997: Yasuo Komatsu; T Tujino; Takahiro Suzuki; Osamu Nikaido; Eiko Ohtsuka
Preliminary studies for interaction of a cyclobutane thymine dimer region with its cognate antibody.
Nucleic acids symposium series 1997;(37):281-2.
1997: M Fukuoka; T Yamauchi; S Koizume; H Inoue; Eiko Ohtsuka
Mechanistic studies on the neighboring base damage induced by KMnO4 oxidation of 8-oxoguanine in DNA.
Nucleic acids symposium series 1997;(37):81-2.
1996: S Iwai; M Wakasa; Eiko Ohtsuka; S Kanaya; A Kidera; H Nakamura
Interaction of the basic protrusion of Escherichia coli ribonuclease HI with its substrate.
Journal of molecular biology 1996;263(5):699-706.
1996: J Kawakami; K Yuda; Y A Suh; PARMOD KUMAR; Fumiko Nishikawa; H Maeda; Kazunari Taira; Eiko Ohtsuka; Shin-Ichi Nishikawa
Constructing an efficient trans-acting genomic HDV ribozyme.
FEBS letters 1996;394(2):132-6.
1996: Yasuo Komatsu; I Kanzaki; Eiko Ohtsuka
Enhanced folding of hairpin ribozymes with replaced domains.
Biochemistry 1996;35(30):9815-20.
1996: M Shimizu; Hiroshi Morioka; H Inoue; Eiko Ohtsuka
Triplex-mediated cleavage of DNA by 1,10-phenanthroline-linked 2'-O-methyl RNA.
FEBS letters 1996;384(3):207-10.
1996: T Nishizaki; S Iwai; T Ohkubo; C Kojima; H Nakamura; Y Kyogoku; Eiko Ohtsuka
Solution Strucutres of DNA duplexes containing a DNA x RNA hybrid region, d(GG)r(AGAU)d(GAC) x d(GTCATCTCC) and d(GGAGA)r(UGAC) x d(GTCATCTCC).
Biochemistry 1996;35(13):4016-25.
1995: K Fukuda; Hiroshi Morioka; S Imajou; S Ikeda; Eiko Ohtsuka; T Tsurimoto
Structure-function relationship of the eukaryotic DNA replication factor, proliferating cell nuclear antigen.
The Journal of biological chemistry 1995;270(38):22527-34.
1995: Yasuo Komatsu; I Kanzaki; M Koizumi; Eiko Ohtsuka
Modification of primary structures of hairpin ribozymes for probing active conformations.
Journal of molecular biology 1995;252(3):296-304.
1995: S Iwai; S Kataoka; M Wakasa; Eiko Ohtsuka; H Nakamura
Recognition of 2'-hydroxyl groups by Escherichia coli ribonuclease HI.
FEBS letters 1995;368(2):315-20.
1995: Eiko Ohtsuka
[Achievement of Dr. H. G. Khorana and nucleic acids chemistry].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(10):1674-6.
1995: Eiko Ohtsuka; J Kawakami
[Structure and molecular design of ribozymes].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(10):1400-7.
1995: S Iwai; M Maeda; M Shirai; Y Shimada; T Osafune; T Murata; Eiko Ohtsuka
Reaction mechanism of T4 endonuclease V determined by analysis using modified oligonucleotide duplexes.
Biochemistry 1995;34(14):4601-9.
1995: H Kamiya; N Murata-Kamiya; S Koizume; H Inoue; S Nishimura; Eiko Ohtsuka
8-Hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene: effects of sequence contexts on mutation spectra.
Carcinogenesis 1995;16(4):883-9.
1995: H Kamiya; N Murata-Kamiya; M Fujimuro; K Kido; H Inoue; S Nishimura; C Masutani; F Hanaoka; Eiko Ohtsuka
Comparison of incorporation and extension of nucleotides in vitro opposite 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene.
Japanese journal of cancer research : Gann 1995;86(3):270-6.
1995: Yasuo Komatsu; I Kanzaki; M Koizumi; Eiko Ohtsuka
Construction of new hairpin ribozymes with replaced domains.
Nucleic acids symposium series 1995;(34):223-4.
1994: Y Uchiyama; S Iwai; Yoshio Ueno; M Ikehara; Eiko Ohtsuka
Role of the Mg2+ ion in the Escherichia coli ribonuclease HI reaction.
Journal of biochemistry 1994;116(6):1322-9.
1994: Y Uchiyama; Y Miura; H Inoue; Eiko Ohtsuka; Yoshio Ueno; M Ikehara; S Iwai
Studies of the interactions between Escherichia coli ribonuclease HI and its substrate.
Journal of molecular biology 1994;243(4):782-91.
1994: Eiko Ohtsuka
[Synthesis and functional studies on nucleic acids. Problems related to synthetic ras genes].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1994;114(10):747-64.
1994: S Iwai; Eiko Ohtsuka
[DNA/RNA synthesizers].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1994;39(11):1788-99.
1994: Y Uchiyama; H Inoue; Eiko Ohtsuka; C Nakai; S Kanaya; Yoshio Ueno; M Ikehara
DNA-linked RNase H for site-selective cleavage of RNA.
Bioconjugate chemistry 1994;5(4):327-32.
1994: S Iwai; M Maeda; Y Shimada; N Hori; T Murata; Hiroshi Morioka; Eiko Ohtsuka
Endonuclease V from bacteriophage T4 interacts with its substrate in the minor groove.
Biochemistry 1994;33(18):5581-8.
1994: M Shimizu; H Inoue; Eiko Ohtsuka
Detailed study of sequence-specific DNA cleavage of triplex-forming oligonucleotides linked to 1,10-phenanthroline.
Biochemistry 1994;33(2):606-13.
1993: J Kawakami; PARMOD KUMAR; Y A Suh; Fumiko Nishikawa; K Kawakami; Kazunari Taira; Eiko Ohtsuka; Shin-Ichi Nishikawa
Identification of important bases in a single-stranded region (SSrC) of the hepatitis delta (delta) virus ribozyme.
European journal of biochemistry / FEBS 1993;217(1):29-36.
1993: M Koizumi; H Kamiya; Eiko Ohtsuka
Inhibition of c-Ha-ras gene expression by hammerhead ribozymes containing a stable C(UUCG)G hairpin loop.
Biological & pharmaceutical bulletin 1993;16(9):879-83.
1993: H Kamiya; M Suzuki; Eiko Ohtsuka
Mutation-spectrum of a true abasic site in codon 12 of a c-Ha-ras gene in mammalian cells.
FEBS letters 1993;328(1-2):125-9.
1993: H Kamiya; N Murata; T Murata; S Iwai; A Matsukage; C Masutani; F Hanaoka; Eiko Ohtsuka
Cyclobutane thymine dimers in a ras proto-oncogene hot spot activate the gene by point mutation.
Nucleic acids research 1993;21(10):2355-61.
1993: Eiko Ohtsuka; M Shimizu
[Recognition and cleavage of duplex DNA by modified oligonucleotides via triple-helix formation].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1993;38(3):503-15.
1993: Yasuo Komatsu; M Koizumi; A Sekiguchi; Eiko Ohtsuka
Cross-ligation and exchange reactions catalyzed by hairpin ribozymes.
Nucleic acids research 1993;21(2):185-90.
1993: Shin-Ichi Nishikawa; PARMOD KUMAR; Y H Jeoung; J Kawakami; Fumiko Nishikawa; Y Suh; Eiko Ohtsuka; Kazunari Taira
Chemical probing studies of the hepatitis delta virus (HDV) genomic ribozyme.
Nucleic acids symposium series 1993;(29):119-20.
1993: Hiroshi Morioka; H Miura; H Kamiya; T Matsunaga; Osamu Nikaido; Eiko Ohtsuka
Cloning of VH and VL genes for antibodies specific for pyrimidine photo dimers.
Nucleic acids symposium series 1993;(29):111-2.
1992: M Koizumi; Eiko Ohtsuka
Design of RNAs that inhibit the activated c-Ha-ras gene in mammalian cells.
Annals of the New York Academy of Sciences 1992;660():276.
1992: N Hori; T Doi; Y Karaki; M Kikuchi; M Ikehara; Eiko Ohtsuka
Participation of glutamic acid 23 of T4 endonuclease V in the beta-elimination reaction of an abasic site in a synthetic duplex DNA.
Nucleic acids research 1992;20(18):4761-4.
1992: H Kamiya; M Suzuki; Yasuo Komatsu; H Miura; K Kikuchi; T Sakaguchi; N Murata; C Masutani; F Hanaoka; Eiko Ohtsuka
An abasic site analogue activates a c-Ha-ras gene by a point mutation at modified and adjacent positions.
Nucleic acids research 1992;20(17):4409-15.
1992: M Koizumi; H Kamiya; Eiko Ohtsuka
Ribozymes designed to inhibit transformation of NIH3T3 cells by the activated c-Ha-ras gene.
Gene 1992;117(2):179-84.
1992: N Hori; S Iwai; H Inoue; Eiko Ohtsuka
Photoaffinity labeling of T4 endonuclease V with a substrate containing a phenyldiazirine derivative.
The Journal of biological chemistry 1992;267(22):15591-4.
1992: H Kamiya; K Miura; H Ishikawa; H Inoue; S Nishimura; Eiko Ohtsuka
c-Ha-ras containing 8-hydroxyguanine at codon 12 induces point mutations at the modified and adjacent positions.
Cancer research 1992;52(12):3483-5.
1992: M Shimizu; A Konishi; Y Shimada; H Inoue; Eiko Ohtsuka
Oligo(2'-O-methyl)ribonucleotides. Effective probes for duplex DNA.
FEBS letters 1992;302(2):155-8.
1992: H Kamiya; H Miura; H Kato; S Nishimura; Eiko Ohtsuka
Induction of mutation of a synthetic c-Ha-ras gene containing hypoxanthine.
Cancer research 1992;52(7):1836-9.
1992: K Kido; H Inoue; Eiko Ohtsuka
Sequence-dependent cleavage of DNA by alkylation with antisense oligodeoxyribonucleotides containing a 2-(N-iodoacetylaminoethyl)thio-adenine.
Nucleic acids research 1992;20(6):1339-44.
1992: Yasuo Komatsu; M Koizumi; A Sekiguchi; Eiko Ohtsuka
Cross-ligation and exchange reaction of RNA catalyzed by hairpin ribozymes.
Nucleic acids symposium series 1992;(27):43-4.
1991: A Sekiguchi; Yasuo Komatsu; M Koizumi; Eiko Ohtsuka
Mutagenesis and self-ligation of the self-cleavage domain of the satellite RNA minus strand of tobacco ringspot virus and its binding to polyamines.
Nucleic acids research 1991;19(24):6833-8.
1991: H Kamiya; K Miura; N Ohtomo; S Nishimura; Eiko Ohtsuka
Transforming activity of a synthetic c-Ha-ras gene containing O6-methylguanine in codon 12.
Japanese journal of cancer research : Gann 1991;82(9):997-1002.
1991: M Koizumi; Eiko Ohtsuka
Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding.
Biochemistry 1991;30(21):5145-50.
1991: M Shimizu; H Inoue; Eiko Ohtsuka
Design of oligonucleotides for sequence-specific triple-helix formation. Properties of oligonucleotides containing 2'-deoxyxanthosine.
Nucleic acids symposium series 1991;(25):141-2.
1990: T Murata; S Iwai; Eiko Ohtsuka
Synthesis and characterization of a substrate for T4 endonuclease V containing a phosphorodithioate linkage at the thymine dimer site.
Nucleic acids research 1990;18(24):7279-86.
1990: Eiko Ohtsuka; H Kamiya
[Chemical synthesis of c-Ha-ras genes and their expression in Escherichia coli].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(14):2382-90.
1990: M Koizumi; Eiko Ohtsuka
[Ribozyme for sequence-dependent cleavage of target RNA].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(13):2191-200.
1990: Y Hayase; H Inoue; Eiko Ohtsuka
Secondary structure in formylmethionine tRNA influences the site-directed cleavage of ribonuclease H using chimeric 2'-O-methyl oligodeoxyribonucleotides.
Biochemistry 1990;29(37):8793-7.
1990: M Ishida; Y Kanamori; N Hori; T Inaoka; Eiko Ohtsuka
In vitro and in vivo activities of T4 endonuclease V mutants altered in the C-terminal aromatic region.
Biochemistry 1990;29(16):3817-21.
1990: T Sasaki; S Iwai; S Tsuda; K Hikichi; Eiko Ohtsuka
Chemical synthesis of oligoribonucleotides for structural studies.
Nucleic acids symposium series 1990;(22):43-4.
1989: J M Ha; Yoshiaki Ito; Gota Kawai; Takayuki Miyazawa; K i Miura; Eiko Ohtsuka; S Noguchi; Susumu Nishimura; Shigeyuki Yokoyama
Conformation of guanosine 5'-diphosphate as bound to a human c-Ha-ras mutant protein: a nuclear Overhauser effect study.
Biochemistry 1989;28(21):8411-6.
1989: M Koizumi; Y Hayase; S Iwai; H Kamiya; H Inoue; Eiko Ohtsuka
Design of RNA enzymes distinguishing a single base mutation in RNA.
Nucleic acids research 1989;17(17):7059-71.
1989: H Kamiya; K Miura; N Ohtomo; T Koda; M Kakinuma; S Nishimura; Eiko Ohtsuka
Transformation of NIH3T3 cells with synthetic c-Ha-ras genes.
Japanese journal of cancer research : Gann 1989;80(3):200-3.
1989: M Koizumi; Y Hayase; S Iwai; H Kamiya; H Inoue; Eiko Ohtsuka
Design of RNA enzymes for sequence-dependent cleavage of RNA.
Nucleic acids symposium series 1989;(21):107-8.
1988: M Koizumi; S Iwai; Eiko Ohtsuka
Cleavage of specific sites of RNA by designed ribozymes.
FEBS letters 1988;239(2):285-8.
1988: S Iwai; Eiko Ohtsuka
5'-Levulinyl and 2'-tetrahydrofuranyl protection for the synthesis of oligoribonucleotides by the phosphoramidite approach.
Nucleic acids research 1988;16(20):9443-56.
1988: K Miura; H Kamiya; S Kubota; M Ikehara; S Nishimura; Eiko Ohtsuka
Conversion of the guanine nucleotide binding sites of ras protein resulting in the reduction of base specificity.
Protein engineering 1988;2(3):227-31.
1988: M Koizumi; S Iwai; Eiko Ohtsuka
Construction of a series of several self-cleaving RNA duplexes using synthetic 21-mers.
FEBS letters 1988;228(2):228-30.
1988: H Inoue; Y Hayase; S Iwai; Eiko Ohtsuka
Sequence-specific cleavage of RNA using chimeric DNA splints and RNase H.
Nucleic acids symposium series 1988;(19):135-8.
1987: H Inoue; Y Hayase; S Iwai; Eiko Ohtsuka
Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H.
Nucleic acids symposium series 1987;(18):221-4.