FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Iwao Ohtsuki

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Phenomena

Muscle Contraction

Disorders

Procedures

Electrophoresis, Polyacrylamide Gel

Co-author Network

Publications

TOP 3
Yusuke S Kato; Takuya Miyakawa; Yumiko Miyauchi; Iwao Ohtsuki; Takao Ojima; Yoriko Sawano; Daijiro Takeshita; Hiroyuki Tanaka; Fumiaki Yumoto; Masaru Tanokura
Structure of the Ca(2+)-saturated C-terminal domain of scallop troponin C in complex with a troponin I fragment.
Naoto Tadano; Cheng-Kun Du; Fumiaki Yumoto; Sachio Morimoto; Mika Ohta; Ming-Fang Xie; Koji Nagata; Dong-Yun Zhan; Qun-Wei Lu; Yoshikazu Miwa; Fumi Takahashi-Yanaga; Masaru Tanokura; Iwao Ohtsuki; Toshiyuki Sasaguri
Biological actions of green tea catechins on cardiac troponin C.
Naoto Tadano; Sachio Morimoto; Fumi Takahashi-Yanaga; Yoshikazu Miwa; Iwao Ohtsuki; Toshiyuki Sasaguri
Propyl gallate, a strong antioxidant, increases the Ca2+ sensitivity of cardiac myofilament.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Iwao Ohtsuki (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Yusuke S Kato; Takuya Miyakawa; Yumiko Miyauchi; Iwao Ohtsuki; Takao Ojima; Yoriko Sawano; Daijiro Takeshita; Hiroyuki Tanaka; Fumiaki Yumoto; Masaru Tanokura
Structure of the Ca(2+)-saturated C-terminal domain of scallop troponin C in complex with a troponin I fragment.
Biological chemistry 2013;394(1):55-68.
2010: Naoto Tadano; Cheng-Kun Du; Fumiaki Yumoto; Sachio Morimoto; Mika Ohta; Ming-Fang Xie; Koji Nagata; Dong-Yun Zhan; Qun-Wei Lu; Yoshikazu Miwa; Fumi Takahashi-Yanaga; Masaru Tanokura; Iwao Ohtsuki; Toshiyuki Sasaguri
Biological actions of green tea catechins on cardiac troponin C.
British journal of pharmacology 2010;161(5):1034-43.
2009: Naoto Tadano; Sachio Morimoto; Fumi Takahashi-Yanaga; Yoshikazu Miwa; Iwao Ohtsuki; Toshiyuki Sasaguri
Propyl gallate, a strong antioxidant, increases the Ca2+ sensitivity of cardiac myofilament.
Journal of pharmacological sciences 2009;109(3):456-8.
2007: Cheng-Kun Du; Sachio Morimoto; Kiyomasa Nishii; Reiko Minakami; Mika Ohta; Naoto Tadano; Qun-Wei Lu; Yuan-Yuan Wang; Dong-Yun Zhan; Misato Mochizuki; Satomi Kita; Yoshikazu Miwa; Fumi Takahashi-Yanaga; Takahiro Iwamoto; Iwao Ohtsuki; Toshiyuki Sasaguri
Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation.
Circulation research 2007;101(2):185-94.
2007: Fumiaki Yumoto; Koji Nagata; Yumiko Miyauchi; Takao Ojima; Hiroyuki Tanaka; Kiyoyoshi Nishita; Iwao Ohtsuki; Masaru Tanokura
Crystallization and preliminary X-ray analysis of the Ca2+-bound C-terminal lobe of troponin C in complex with a troponin I-derived peptide fragment from Akazara scallop.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 6):535-7.
2005: Fumiaki Yumoto; Qun-Wei Lu; Sachio Morimoto; Hiroyuki Tanaka; Naoko Kono; Koji Nagata; Takao Ojima; Fumi Takahashi-Yanaga; Yoshikazu Miwa; Toshiyuki Sasaguri; Kiyoyoshi Nishita; Masaru Tanokura; Iwao Ohtsuki
Drastic Ca2+ sensitization of myofilament associated with a small structural change in troponin I in inherited restrictive cardiomyopathy.
Biochemical and biophysical research communications 2005;338(3):1519-26.
2005: Hiroyuki Tanaka; Yuhei Takeya; Teppei Doi; Fumiaki Yumoto; Masaru Tanokura; Iwao Ohtsuki; Kiyoyoshi Nishita; Takao Ojima
Comparative studies on the functional roles of N- and C-terminal regions of molluskan and vertebrate troponin-I.
The FEBS journal 2005;272(17):4475-86.
2005: Teppei Doi; Ai Satoh; Hiroyuki Tanaka; Akira Inoue; Fumiaki Yumoto; Masaru Tanokura; Iwao Ohtsuki; Kiyoyoshi Nishita; Takao Ojima
Functional importance of Ca2+-deficient N-terminal lobe of molluscan troponin C in troponin regulation.
Archives of biochemistry and biophysics 2005;436(1):83-90.
2005: Naoto Tadano; Sachio Morimoto; Akira Yoshimura; Makoto Miura; Kimitomo Yoshioka; Mitsuo Sakato; Iwao Ohtsuki; Yoshikazu Miwa; Fumi Takahashi-Yanaga; Toshiyuki Sasaguri
SCH00013, a novel Ca(2+) sensitizer with positive inotropic and no chronotropic action in heart failure.
Journal of pharmacological sciences 2005;97(1):53-60.
2003: Qun-Wei Lu; Sachio Morimoto; Keita Harada; Cheng-Kun Du; Fumi Takahashi-Yanaga; Yoshikazu Miwa; Toshiyuki Sasaguri; Iwao Ohtsuki
Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
Journal of molecular and cellular cardiology 2003;35(12):1421-7.
2003: Iwao Ohtsuki; Sachio Morimoto; Fumi Takahashi-Yanaga
Several aspects of calcium regulator mechanisms linked to troponin.
Advances in experimental medicine and biology 2003;538():221-9; discussion 229.
2003: Fumiaki Yumoto; Koji Nagata; Kyoko Adachi; Nobuaki Nemoto; Takao Ojima; Kiyoyoshi Nishita; Iwao Ohtsuki; Masaru Tanokura
NMR structural study of troponin C C-terminal domain complexed with troponin I fragment from Akazara scallop.
Advances in experimental medicine and biology 2003;538():195-200; discussion 201.
2002: Iwao Ohtsuki; Fumie Shiraishi
Periodic binding of troponin C.I and troponin I to tropomyosin-actin filaments.
Journal of biochemistry 2002;131(5):739-43.
2002: Sachio Morimoto; Qun-Wei Lu; Keita Harada; Fumi Takahashi-Yanaga; Reiko Minakami; Mika Ohta; Toshiyuki Sasaguri; Iwao Ohtsuki
Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):913-8.
2001: Fumi Takahashi-Yanaga; Sachio Morimoto; Keita Harada; Reiko Minakami; Fumie Shiraishi; Mika Ohta; Qun-Wei Lu; Toshiyuki Sasaguri; Iwao Ohtsuki
Functional consequences of the mutations in human cardiac troponin I gene found in familial hypertrophic cardiomyopathy.
Journal of molecular and cellular cardiology 2001;33(12):2095-107.
2001: Iwao Ohtsuki
[Molecular mechanisms of calcium regulation of striated muscle contraction and its genetic disorder].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2001;118(3):147-58.
2001: Fumi Takahashi-Yanaga; Iwao Ohtsuki; Sachio Morimoto
Effects of troponin T mutations in familial hypertrophic cardiomyopathy on regulatory functions of other troponin subunits.
Journal of biochemistry 2001;130(1):127-31.
2001: Sachio Morimoto; Mika Ohta; T Goto; Iwao Ohtsuki
A pH-sensitive interaction of troponin I with troponin C coupled with strongly binding cross-bridges in cardiac myofilament activation.
Biochemical and biophysical research communications 2001;282(3):811-5.
2000: Fumi Takahashi-Yanaga; Sachio Morimoto; Iwao Ohtsuki
Effect of Arg145Gly mutation in human cardiac troponin I on the ATPase activity of cardiac myofibrils.
Journal of biochemistry 2000;127(3):355-7.
2000: Keita Harada; Fumi Takahashi-Yanaga; Reiko Minakami; Sachio Morimoto; Iwao Ohtsuki
Functional consequences of the deletion mutation deltaGlu160 in human cardiac troponin T.
Journal of biochemistry 2000;127(2):263-8.
1999: Fumie Shiraishi; Sachio Morimoto; Kiyoyoshi Nishita; Takao Ojima; Iwao Ohtsuki
Effects of removal and reconstitution of myosin regulatory light chain and troponin C on the Ca(2+)-sensitive ATPase activity of myofibrils from scallop striated muscle.
Journal of biochemistry 1999;126(6):1020-4.
1999: H Nakaura; F Yanaga; Iwao Ohtsuki; Sachio Morimoto
Effects of missense mutations Phe110Ile and Glu244Asp in human cardiac troponin T on force generation in skinned cardiac muscle fibers.
Journal of biochemistry 1999;126(3):457-60.
1999: H Nakaura; Sachio Morimoto; F Yanaga; M Nakata; H Nishi; T Imaizumi; Iwao Ohtsuki
Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy.
The American journal of physiology 1999;277(2 Pt 1):C225-32.
1999: Sachio Morimoto; H Nakaura; F Yanaga; Iwao Ohtsuki
Functional consequences of a carboxyl terminal missense mutation Arg278Cys in human cardiac troponin T.
Biochemical and biophysical research communications 1999;261(1):79-82.
1999: Sachio Morimoto; Keita Harada; Iwao Ohtsuki
Roles of troponin isoforms in pH dependence of contraction in rabbit fast and slow skeletal and cardiac muscles.
Journal of biochemistry 1999;126(1):121-9.
1999: F Yanaga; Sachio Morimoto; Iwao Ohtsuki
Ca2+ sensitization and potentiation of the maximum level of myofibrillar ATPase activity caused by mutations of troponin T found in familial hypertrophic cardiomyopathy.
The Journal of biological chemistry 1999;274(13):8806-12.
1999: Iwao Ohtsuki
Calcium ion regulation of muscle contraction: the regulatory role of troponin T.
Molecular and cellular biochemistry 1999;190(1-2):33-8.
1998: T Goto; F Yanaga; Iwao Ohtsuki
Studies on the endothelin-1-induced contraction of rat granulation tissue pouch mediated by myofibroblasts.
Biochimica et biophysica acta 1998;1405(1-3):55-66.
1998: Sachio Morimoto; Iwao Ohtsuki
[Calcium regulation of contraction and relaxation in skeletal muscle].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(12 Suppl):1744-52.
1998: Sachio Morimoto; F Yanaga; Reiko Minakami; Iwao Ohtsuki
Ca2+-sensitizing effects of the mutations at Ile-79 and Arg-92 of troponin T in hypertrophic cardiomyopathy.
The American journal of physiology 1998;275(1 Pt 1):C200-7.
1996: Sachio Morimoto; Iwao Ohtsuki
Reduced positive feedback regulation between myosin crossbridge and cardiac troponin C in fast skeletal myofibrils.
Journal of biochemistry 1996;119(4):737-42.
1995: A Kawashima; Sachio Morimoto; A Suzuki; Fumie Shiraishi; Iwao Ohtsuki
Troponin isoform dependent pH dependence of the Ca(2+)-activated myofibrillar ATPase activity of avian slow and fast skeletal muscles.
Biochemical and biophysical research communications 1995;207(2):585-92.
1994: Sachio Morimoto; Iwao Ohtsuki
Ca2+ binding to cardiac troponin C in the myofilament lattice and its relation to the myofibrillar ATPase activity.
European journal of biochemistry / FEBS 1994;226(2):597-602.
1994: Y Nakamura; Fumie Shiraishi; Iwao Ohtsuki
The effect of troponin C substitution on the Ca(2+)-sensitive ATPase activity of vertebrate and invertebrate myofibrils by troponin Cs with various numbers of Ca(2+)-binding sites.
Comparative biochemistry and physiology. Biochemistry and molecular biology 1994;108(1):121-33.
1994: A Kawashima; Fumie Shiraishi; Iwao Ohtsuki; K Yamamoto
The exchange of Ca(2+)-receptive protein complex (troponin) in the myofibrils of fast and slow skeletal muscles.
Molecular and cellular biochemistry 1994;132(2):173-7.
1994: Sachio Morimoto; Iwao Ohtsuki
Role of troponin C in determining the Ca(2+)-sensitivity and cooperativity of the tension development in rabbit skeletal and cardiac muscles.
Journal of biochemistry 1994;115(1):144-6.
1993: Fumie Shiraishi; Iwao Ohtsuki; K Yamamoto
Effect of troponin T-treatment on the composition of rabbit skeletal myofibrils.
Fukuoka igaku zasshi = Hukuoka acta medica 1993;84(11):449-52.
1992: M Tanokura; M Imaizumi; K Yamada; Fumie Shiraishi; Iwao Ohtsuki
Preparation and characterization of troponin C from bullfrog skeletal muscle.
Journal of biochemistry 1992;112(6):800-3.
1992: Fumie Shiraishi; Iwao Ohtsuki; T Ojima; K Nishita
Ca(2+)-and Sr(2+)-sensitivity of Akazara scallop troponin.
Fukuoka igaku zasshi = Hukuoka acta medica 1992;83(10):383-5.
1992: M Hatakenaka; Iwao Ohtsuki
Effect of removal and reconstitution of troponins C and I on the Ca(2+)-activated tension development of single glycerinated rabbit skeletal muscle fibers.
European journal of biochemistry / FEBS 1992;205(3):985-93.
1992: Fumie Shiraishi; M Kambara; Iwao Ohtsuki
Replacement of troponin components in myofibrils.
Journal of biochemistry 1992;111(1):61-5.
1991: M Hatakenaka; Iwao Ohtsuki
Replacement of three troponin components with cardiac troponin components within single glycerinated skeletal muscle fibers.
Biochemical and biophysical research communications 1991;181(3):1022-7.
1990: Fumie Shiraishi; Iwao Ohtsuki
Ca2(+)- and Sr2(+)-sensitivity of the ATPase of myofibrils and natural actomyosins prepared from various muscles.
Fukuoka igaku zasshi = Hukuoka acta medica 1990;81(7):237-41.
1990: Fumie Shiraishi; Iwao Ohtsuki
Properties of desensitized myosin B of chicken gizzard.
Fukuoka igaku zasshi = Hukuoka acta medica 1990;81(6):221-5.
1989: Fumie Shiraishi; Iwao Ohtsuki
Removal of troponin C from natural actomyosin of rabbit skeletal muscle by CDTA.
Fukuoka igaku zasshi = Hukuoka acta medica 1989;80(4):167-9.
1989: Sachio Morimoto; Iwao Ohtsuki
Ca2+ binding to skeletal muscle troponin C in skeletal and cardiac myofibrils.
Journal of biochemistry 1989;105(3):435-9.
1989: Iwao Ohtsuki; Sachio Morimoto
Calcium regulation of myofibrillar contraction.
Progress in clinical and biological research 1989;315():213-4.
1988: Sachio Morimoto; T Fujiwara; Iwao Ohtsuki
Restoration of Ca2+-activated tension of CDTA-treated single skeletal muscle fibers by troponin C.
Journal of biochemistry 1988;104(6):873-4.
1988: Sachio Morimoto; Iwao Ohtsuki
Effect of substitution of troponin C in cardiac myofibrils with skeletal troponin C or calmodulin on the Ca2+- and Sr2+-sensitive ATPase activity.
Journal of biochemistry 1988;104(1):149-54.
1988: Iwao Ohtsuki; Y Onoyama; Fumie Shiraishi
Electron microscopic study of troponin.
Journal of biochemistry 1988;103(6):913-9.
1986: Fumie Shiraishi; Iwao Ohtsuki
Effect of trifluoperazine on the Ca2+-sensitive actomyosin ATPase of cardiac and skeletal muscle.
Fukuoka igaku zasshi = Hukuoka acta medica 1986;77(11):591-3.
1984: Iwao Ohtsuki; Fumie Shiraishi; N Suenaga; T Miyata; M Tanokura
A 26K fragment of troponin T from rabbit skeletal muscle.
Journal of biochemistry 1984;95(5):1337-42.
1982: N Suenaga; Iwao Ohtsuki
Effect of troponin and tropomyosin on the interaction between cytochalasin B and actin filaments.
Journal of biochemistry 1982;91(4):1249-56.