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Akira Ohtsuru

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sadanori akita; Kenji Hayashida; Akiyoshi Hirano; Akira Ohtsuru; Keiji Suzuki; Kozo Akino; Hiroshi Yoshimoto; Shunichi Yamashita
Early experiences with stem cells in treating chronic wounds.
EunSook Kim; Michiko Matsuse; Norisato Mitsutake; Akira Ohtsuru; Vladimir Saenko; Keiji Suzuki; Shunichi Yamashita
Imatinib enhances docetaxel-induced apoptosis through inhibition of nuclear factor-κB activation in anaplastic thyroid carcinoma cells.
Akira Ohtsuru; Shunichi Yamashita
[Anaplastic thyroid carcinoma].

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2012: sadanori akita; Kenji Hayashida; Akiyoshi Hirano; Akira Ohtsuru; Keiji Suzuki; Kozo Akino; Hiroshi Yoshimoto; Shunichi Yamashita
Early experiences with stem cells in treating chronic wounds.
Clinics in plastic surgery 2012;39(3):281-92.
2012: EunSook Kim; Michiko Matsuse; Norisato Mitsutake; Akira Ohtsuru; Vladimir Saenko; Keiji Suzuki; Shunichi Yamashita
Imatinib enhances docetaxel-induced apoptosis through inhibition of nuclear factor-κB activation in anaplastic thyroid carcinoma cells.
Thyroid : official journal of the American Thyroid Association 2012;22(7):717-24.
2011: Akira Ohtsuru; Shunichi Yamashita
[Anaplastic thyroid carcinoma].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 2():356-61.
2011: Keiji Suzuki; Norisato Mitsutake; Vladimir Saenko; Masatoshi Suzuki; Michiko Matsuse; Akira Ohtsuru; Atsushi Kumagai; Tatsuya Uga; Hiroshi Yano; Yuji Nagayama; Shunichi Yamashita
Dedifferentiation of human primary thyrocytes into multilineage progenitor cells without gene introduction.
PloS one 2011;6(4):e19354.
2010: sadanori akita; Kozo Akino; Akiyoshi Hirano; Akira Ohtsuru; Shunichi Yamashita
Mesenchymal stem cell therapy for cutaneous radiation syndrome.
Health physics 2010;98(6):858-62.
2010: sadanori akita; Kozo Akino; Akiyoshi Hirano; Akira Ohtsuru; Shunichi Yamashita
Noncultured autologous adipose-derived stem cells therapy for chronic radiation injury.
Stem cells international 2010;2010():532704.
2008: Zhaowei Meng; Norisato Mitsutake; Masahiro Nakashima; Dmitriy Starenki; Michiko Matsuse; Shu Takakura; Hiroyuki Namba; Vladimir Saenko; Kazuo Umezawa; Akira Ohtsuru; Shunichi Yamashita
Dehydroxymethylepoxyquinomicin, a novel nuclear Factor-kappaB inhibitor, enhances antitumor activity of taxanes in anaplastic thyroid cancer cells.
Endocrinology 2008;149(11):5357-65.
2008: Sachio Makino; Norisato Mitsutake; Masahiro Nakashima; Vladimir Saenko; Akira Ohtsuru; Kazuo Umezawa; Katsumi Tanaka; Akiyoshi Hirano; Shunichi Yamashita
DHMEQ, a novel NF-kappaB inhibitor, suppresses growth and type I collagen accumulation in keloid fibroblasts.
Journal of dermatological science 2008;51(3):171-80.
2008: Shu Takakura; Norisato Mitsutake; Masahiro Nakashima; Hiroyuki Namba; Vladimir Saenko; Tatiana Rogounovitch; Yuka Nakazawa; Tomayoshi Hayashi; Akira Ohtsuru; Shunichi Yamashita
Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells.
Cancer science 2008;99(6):1147-54.
2007: Tsuyoshi Izumo; Akira Ohtsuru; Yoshiharu Tokunaga; Hiroyuki Namba; Yasufumi Kaneda; Izumi Nagata; Shunichi Yamashita
Epstein-Barr virus-based vector improves the tumor cell killing effect of pituitary tumor in HVJ-liposome-mediated transcriptional targeting suicide gene therapy.
International journal of oncology 2007;31(2):379-87.
2007: Atsushi Kumagai; Hiroyuki Namba; Zhanay Akanov; Vladimir Saenko; Serik Meirmanov; Akira Ohtsuru; Hiroshi Yano; Shigeto Maeda; Masanobu Anami; Tomayoshi Hayashi; Masahiro Ito; Sagadat Sagandikova; Zhanar Eleubaeva; Daniyal Mussinov; Maira Espenbetova; Shunichi Yamashita
Clinical implications of pre-operative rapid BRAF analysis for papillary thyroid cancer.
Endocrine journal 2007;54(3):399-405.
2007: Norisato Mitsutake; Atsuhiko Iwao; Kazuhiro Nagai; Hiroyuki Namba; Akira Ohtsuru; Vladimir Saenko; Shunichi Yamashita
Characterization of side population in thyroid cancer cell lines: cancer stem-like cells are enriched partly but not exclusively.
Endocrinology 2007;148(4):1797-803.
2007: Nader Ghotbi; Masako Iwanaga; Akira Ohtsuru; Yoji Ogawa; Shunichi Yamashita
Cancer screening with whole-body PET/CT for healthy asymptomatic people in Japan: re-evaluation of its test validity and radiation exposure.
Asian Pacific journal of cancer prevention : APJCP 2007;8(1):93-7.
2007: Osami Sato; Naoto Ashizawa; Akira Ohtsuru; Ryo Imanishi; Hiroaki Kawano; Shinji Seto; Shunichi Yamashita; Isao Shimokawa; Katsusuke Yano
Fibrotic response to angiotensin II is blunted in the kidney, but not in the heart, in insulin-sensitive long-lived transgenic dwarf rats.
International journal of molecular medicine 2007;19(1):23-7.
2006: Iryna Palona; Hiroyuki Namba; Norisato Mitsutake; Dmitriy Starenki; Alexei Podtcheko; Ilya Sedliarou; Akira Ohtsuru; Vladimir Saenko; Yuji Nagayama; Kazuo Umezawa; Shunichi Yamashita
BRAFV600E promotes invasiveness of thyroid cancer cells through nuclear factor kappaB activation.
Endocrinology 2006;147(12):5699-707.
2006: Nader Ghotbi; Akira Ohtsuru; Yoji Ogawa; Mariko Morishita; Nana Norimatsu; Hiroyuki Namba; Hiroyuki Moriuchi; Masataka Uetani; Shunichi Yamashita
Pediatric CT scan usage in Japan: results of a hospital survey.
Radiation medicine 2006;24(8):560-7.
2006: Atsushi Kumagai; Hiroyuki Namba; Shu Takakura; Eiko Inamasu; Vladimir Saenko; Akira Ohtsuru; Shunichi Yamashita
No evidence of ARAF, CRAF and MET mutations in BRAFT1799A negative human papillary thyroid carcinoma.
Endocrine journal 2006;53(5):615-20.
2006: Atsushi Kumagai; Hiroyuki Namba; Norisato Mitsutake; Vladimir Saenko; Akira Ohtsuru; Masahiro Ito; Jaeduk Yoshimura Noh; Kiminori Sugino; Koichi Ito; Shunichi Yamashita
Childhood thyroid carcinoma with BRAFT1799A mutation shows unique pathological features of poor differentiation.
Oncology reports 2006;16(1):123-6.
2006: Yujo Kawashita; Hikaru Fujioka; Akira Ohtsuru; Hiroaki Kuroda; Susumu Eguchi; Yasufumi Kaneda; Shunichi Yamashita; Takashi Kanematsu
Total vascular exclusion safely facilitates liver specific gene transfer by the HVJ (sendai virus)-liposome method in rats.
The Journal of surgical research 2006;132(1):136-41.
2006: Dmitry Bulgin; Alexei Podtcheko; Shu Takakura; Norisato Mitsutake; Hiroyuki Namba; Vladimir Saenko; Akira Ohtsuru; Tatiana Rogounovitch; Iryna Palona; Shunichi Yamashita
Selective pharmacologic inhibition of c-Jun NH2-terminal kinase radiosensitizes thyroid anaplastic cancer cell lines via induction of terminal growth arrest.
Thyroid : official journal of the American Thyroid Association 2006;16(3):217-24.
2006: Hajime Isomoto; Akira Ohtsuru; Vera Braiden; Miyoko Iwamatsu; Fumio Miki; Yujo Kawashita; Yohei Mizuta; Yasufumi Kaneda; Shigeru Kohno; Shunichi Yamashita
Heat-directed suicide gene therapy mediated by heat shock protein promoter for gastric cancer.
Oncology reports 2006;15(3):629-35.
2006: Alexei Podtcheko; Akira Ohtsuru; Hiroyuki Namba; Vladimir Saenko; Dmitriy Starenki; Iryna Palona; Ilya Sedliarou; Tatiana Rogounovitch; Shunichi Yamashita
Inhibition of ABL tyrosine kinase potentiates radiation-induced terminal growth arrest in anaplastic thyroid cancer cells.
Radiation research 2006;165(1):35-42.
2005: Yujo Kawashita; Hikaru Fujioka; Akira Ohtsuru; Yasufumi Kaneda; Yukio Kamohara; Yasushi Kawazoe; Shunichi Yamashita; Takashi Kanematsu
The efficacy and safety of gene transfer into the porcine liver in vivo by HVJ (Sendai virus) liposome.
Transplantation 2005;80(11):1623-9.
2005: Yujo Kawashita; Akira Ohtsuru; Fumio Miki; H Kuroda; M Morishita; Yasufumi Kaneda; K Hatsushiba; Takashi Kanematsu; Shunichi Yamashita
Eradication of hepatocellular carcinoma xenografts by radiolabelled, lipiodol-inducible gene therapy.
Gene therapy 2005;12(22):1633-9.
2005: Kozo Akino; sadanori akita; Toru Mizuguchi; Ichiro Takumi; Run Yu; Xhi-yong Wang; Jacek Rozga; Achilles A Demetriou; Shlomo Melmed; Akira Ohtsuru; Shunichi Yamashita
A novel molecular marker of pituitary tumor transforming gene involves in a rat liver regeneration.
The Journal of surgical research 2005;129(1):142-6.
2005: Mariko Morishita; Akira Ohtsuru; Atsushi Kumagai; Hiroyuki Namba; Noriko Sato; Tomayoshi Hayashi; Shunichi Yamashita
Vitamin D3 treatment for locally advanced thyroid cancer: a case report.
Endocrine journal 2005;52(5):613-6.
2005: Hajime Isomoto; Hiroaki Ueno; Vladimir A Saenko; Muhtashan S Mondal; Yoshito Nishi; Naoko Kawano; Ken Ohnita; Yohei Mizuta; Akira Ohtsuru; Shunichi Yamashita; Masamitsu Nakazato; Shigeru Kohno
Impact of Helicobacter pylori infection on gastric and plasma ghrelin dynamics in humans.
The American journal of gastroenterology 2005;100(8):1711-20.
2005: Mariko Morishita; Akira Ohtsuru; Tomayoshi Hayashi; Ichiro Isomoto; Noriaki Itoyanagi; Shigeto Maeda; Sumihisa Honda; Hiroshi Yano; Tatsuya Uga; Takeshi Nagayasu; Takashi Kanematsu; Shunichi Yamashita
Clinical significance of categorisation of mammographic density for breast cancer prognosis.
International journal of oncology 2005;26(5):1307-12.
2005: Alexei Podtcheko; Hiroyuki Namba; Vladimir Saenko; Akira Ohtsuru; Dmitriy Starenki; Serik Meirmanov; Iryna Polona; Tatiana Rogounovitch; Shunichi Yamashita
Radiation-induced senescence-like terminal growth arrest in thyroid cells.
Thyroid : official journal of the American Thyroid Association 2005;15(4):306-13.
2005: Kikuko Iwanaga; Noboru Takamura; Yasuyo Abe; Ye Zhaojia; Ken Shinzato; Hiroshi Hosoda; Kenji Kangawa; Akira Ohtsuru; Shigeru Kohno; Shunichi Yamashita; Kiyoshi Aoyagi
Plasma concentrations of adrenomedullin and ghrelin in hemodialysis patients with sustained and episodic hypotension.
Endocrine journal 2005;52(1):23-8.
2004: Naomi Hayashida; Hiroyuki Namba; Atsushi Kumagai; Tomayoshi Hayashi; Akira Ohtsuru; Masahiro Ito; Vladimir Saenko; Shigeto Maeda; Takashi Kanematsu; Shunichi Yamashita
A rapid and simple detection method for the BRAF(T1796A) mutation in fine-needle aspirated thyroid carcinoma cells.
Thyroid : official journal of the American Thyroid Association 2004;14(11):910-5.
2004: Dmitriy Starenki; Hiroyuki Namba; Vladimir Saenko; Akira Ohtsuru; Shigeto Maeda; Kazuo Umezawa; Shunichi Yamashita
Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(20):6821-9.
2004: Hajime Isomoto; Masamitsu Nakazato; Hiroaki Ueno; Yukari Date; Yoshito Nishi; Hiroshi Mukae; Yohei Mizuta; Akira Ohtsuru; Shunichi Yamashita; Shigeru Kohno
Low plasma ghrelin levels in patients with Helicobacter pylori-associated gastritis.
The American journal of medicine 2004;117(6):429-32.
2004: Akira Ohtsuru; Yasuhiro Nagata; Akihito Enjoji; Takashi Kanematsu; Shunichi Yamashita
[Gastrectomy].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():406-9.
2004: Atsushi Kumagai; Hiroyuki Namba; Vladimir Saenko; Kiyoto Ashizawa; Akira Ohtsuru; Masahiro Ito; Naofumi Ishikawa; Kiminori Sugino; Koichi Ito; Steve Jeremiah; Gerry A Thomas; Tetyana I Bogdanova; Mykola D Tronko; Takeshi Nagayasu; Yoshisada Shibata; Shunichi Yamashita
Low frequency of BRAFT1796A mutations in childhood thyroid carcinomas.
The Journal of clinical endocrinology and metabolism 2004;89(9):4280-4.
2004: Ryo Imanishi; Naoto Ashizawa; Akira Ohtsuru; Shinji Seto; Yuri Akiyama-Uchida; Hiroaki Kawano; Hiroaki Kuroda; Masahiro Nakashima; Vladimir Saenko; Shunichi Yamashita; Katsusuke Yano
GH suppresses TGF-beta-mediated fibrosis and retains cardiac diastolic function.
Molecular and cellular endocrinology 2004;218(1-2):137-46.
2004: Hajime Isomoto; Vladimir A Saenko; Yusei Kanazawa; Yoshito Nishi; Akira Ohtsuru; Kenichiro Inoue; Yuko Akazawa; Fuminao Takeshima; Katsuhisa Omagari; Masanobu Miyazaki; Yohei Mizuta; Ikuo Murata; Shunichi Yamashita; Shigeru Kohno
Enhanced expression of interleukin-8 and activation of nuclear factor kappa-B in endoscopy-negative gastroesophageal reflux disease.
The American journal of gastroenterology 2004;99(4):589-97.
2004: Toshiyuki Nakayama; Ayumi Yoshizaki; N Kawahara; Akira Ohtsuru; Chun-Yang Wen; Eiichiro Fukuda; Masahiro Nakashima; Ichiro Sekine
Expression of Tie-1 and 2 receptors, and angiopoietin-1, 2 and 4 in gastric carcinoma; immunohistochemical analyses and correlation with clinicopathological factors.
Histopathology 2004;44(3):232-9.
2004: Ryo Imanishi; Shinji Seto; Genji Toda; Masanori Yoshida; Akira Ohtsuru; Yuji Koide; Takeshi Baba; Katsusuke Yano
High brachial-ankle pulse wave velocity is an independent predictor of the presence of coronary artery disease in men.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(2):71-8.
2004: Dmitriy Starenki; Hiroyuki Namba; Vladimir Saenko; Akira Ohtsuru; Shunichi Yamashita
Inhibition of nuclear factor-kappaB cascade potentiates the effect of a combination treatment of anaplastic thyroid cancer cells.
The Journal of clinical endocrinology and metabolism 2004;89(1):410-8.
2004: Mariko Morishita; Kaoru Uchimaru; Katsuaki Sato; Akira Ohtsuru; Shunichi Yamashita; Takashi Kanematsu; Naohide Yamashita
Thyroglobulin-pulsed human monocyte-derived dendritic cells induce CD4+ T cell activation.
International journal of molecular medicine 2004;13(1):33-9.
2003: Yusei Kanazawa; Hajime Isomoto; Chun-Yang Wen; Ai-Ping Wang; Vladimir A Saenko; Akira Ohtsuru; Fuminao Takeshima; Katsuhisa Omagari; Yohei Mizuta; Ikuo Murata; Shunichi Yamashita; Shigeru Kohno
Impact of endoscopically minimal involvement on IL-8 mRNA expression in esophageal mucosa of patients with non-erosive reflux disease.
World journal of gastroenterology : WJG 2003;9(12):2801-4.
2003: Hiroyuki Namba; Masahiro Nakashima; Tomayoshi Hayashi; Naomi Hayashida; Shigeto Maeda; Tatiana Rogounovitch; Akira Ohtsuru; Vladimir Saenko; Takashi Kanematsu; Shunichi Yamashita
Clinical implication of hot spot BRAF mutation, V599E, in papillary thyroid cancers.
The Journal of clinical endocrinology and metabolism 2003;88(9):4393-7.
2003: Vladimir Saenko; Tatiana Rogounovitch; Yuki Shimizu-Yoshida; Alexander Abrosimov; Eugeny Lushnikov; Pavel O Roumiantsev; Naomichi Matsumoto; Masahiro Nakashima; Serik Meirmanov; Akira Ohtsuru; Hiroyuki Namba; Anatoly Tsyb; Shunichi Yamashita
Novel tumorigenic rearrangement, Delta rfp/ret, in a papillary thyroid carcinoma from externally irradiated patient.
Mutation research 2003;527(1-2):81-90.
2003: Takehiro Daian; Akira Ohtsuru; Tatiana Rogounovitch; Hiroshi Ishihara; Akiyoshi Hirano; Yuri Akiyama-Uchida; Vladimir Saenko; Tohru Fujii; Shunichi Yamashita
Insulin-like growth factor-I enhances transforming growth factor-beta-induced extracellular matrix protein production through the P38/activating transcription factor-2 signaling pathway in keloid fibroblasts.
The Journal of investigative dermatology 2003;120(6):956-62.
2003: Alexei Podtcheko; Akira Ohtsuru; Satoshi Tsuda; Hiroyuki Namba; Vladimir Saenko; Masahiro Nakashima; Norisato Mitsutake; Shigeru Kanda; Junichi Kurebayashi; Shunichi Yamashita
The selective tyrosine kinase inhibitor, STI571, inhibits growth of anaplastic thyroid cancer cells.
The Journal of clinical endocrinology and metabolism 2003;88(4):1889-96.
2003: Hiroaki Tamura; Akira Ohtsuru; Yukio Kamohara; Hikaru Fujioka; Katsuhiko Yanaga; Takashi Kanematsu; Shunichi Yamashita
Bax cleavage implicates caspase-dependent H2O2-induced apoptosis of hepatocytes.
International journal of molecular medicine 2003;11(3):369-74.
2003: Chun-Yang Wen; Masahiro Ito; Long-Dian Chen; Mutsumi Matsuu; Kazuko Shichijo; Toshiyuki Nakayama; Masahiro Nakashima; Zhao-Min Xu; Akira Ohtsuru; Chao-Tien Hsu; Ichiro Sekine
Expression of Tie-2 and angiopoietin-1 and -2 in early phase of ulcer healing.
Journal of gastroenterology 2003;38(5):431-5.
2003: Masahiro Nakashima; Toshiyuki Nakayama; Akira Ohtsuru; Eiichiro Fukada; Daisuke Niino; Kazuyuki Yamazumi; Shinji Naito; Masahiro Ito; Ichiro Sekine
Expression of parathyroid hormone (PTH)-related peptide (PthrP) and PTH/PTHrP receptor in osteoclast-like giant cells.
Pathology, research and practice 2003;199(2):85-92.
2002: Tatiana Rogounovitch; Vladimir Saenko; Yuki Shimizu-Yoshida; Alexander Abrosimov; Eugeny Lushnikov; Pavel O Roumiantsev; Akira Ohtsuru; Hiroyuki Namba; Anatoly Tsyb; Shunichi Yamashita
Large deletions in mitochondrial DNA in radiation-associated human thyroid tumors.
Cancer research 2002;62(23):7031-41.
2002: Masahiro Ito; Masahiro Nakashima; Toshiyuki Nakayama; Saburo Shikuwa; Akira Ohtsuru; Ichiro Sekine
Preventive effects of parathyroid hormone-related peptide on stress-induced gastric hypercontraction in the rat.
Journal of gastroenterology and hepatology 2002;17(12):1260-6.
2002: Masahiro Ito; Masahiro Nakashima; Toshiyuki Nakayama; Akira Ohtsuru; Yuji Nagayama; Noboru Takamura; Evgeni P Demedchik; Ichiro Sekine; Shunichi Yamashita
Expression of receptor-type tyrosine kinase, Axl, and its ligand, Gas6, in pediatric thyroid carcinomas around chernobyl.
Thyroid : official journal of the American Thyroid Association 2002;12(11):971-5.
2002: Ryo Imanishi; Akira Ohtsuru; Miyoko Iwamatsu; Takashi Iioka; Hiroyuki Namba; Shinji Seto; Katsusuke Yano; Shunichi Yamashita
A histone deacetylase inhibitor enhances killing of undifferentiated thyroid carcinoma cells by p53 gene therapy.
The Journal of clinical endocrinology and metabolism 2002;87(10):4821-4.
2002: Yuri Akiyama-Uchida; Naoto Ashizawa; Akira Ohtsuru; Shinji Seto; Tomoo Tsukazaki; Hiroshi Kikuchi; Shunichi Yamashita; Katsusuke Yano
Norepinephrine enhances fibrosis mediated by TGF-beta in cardiac fibroblasts.
Hypertension 2002;40(2):148-54.
2002: Shinji Naito; Kazuhiro Shimizu; Kozo Akino; Akira Ohtsuru; Masahisa Watanabe; Shunichi Yamashita; Ichiro Sekine
Autocrine/paracrine involvement of parathyroid hormone-related peptide in vascular leiomyoma.
Endocrine journal 2002;49(3):335-41.
2002: Hiroaki Kuroda; Akira Ohtsuru; Mitsuru Futakuchi; Yujo Kawashita; Yuji Nagayama; Eiichiro Fukuda; Hiroyuki Namba; Tomoyuki Shirai; Takashi Kanematsu; Shunichi Yamashita
Distinctive gene expression of receptor-type tyrosine kinase families during rat hepatocarcinogenesis.
International journal of molecular medicine 2002;9(5):473-80.
2002: Satoshi Tsuda; Akira Ohtsuru; Shunichi Yamashita; Hiroshi Kanetake; Shigeru Kanda
Role of c-Fyn in FGF-2-mediated tube-like structure formation by murine brain capillary endothelial cells.
Biochemical and biophysical research communications 2002;290(4):1354-60.
2001: Yuki Shimizu-Yoshida; K Sugiyama; Tatiana Rogounovitch; Akira Ohtsuru; Hiroyuki Namba; Vladimir Saenko; Shunichi Yamashita
Radiation-inducible hSNK gene is transcriptionally regulated by p53 binding homology element in human thyroid cells.
Biochemical and biophysical research communications 2001;289(2):491-8.
2001: SS Shklyaev; Hiroyuki Namba; Norisato Mitsutake; GK Alipov; Y Nagayama; S Maeda; Akira Ohtsuru; H Tsubouchi; Shunichi Yamashita
Transient activation of c-Jun NH2-terminal kinase by growth factors influences survival but not apoptosis of human thyrocytes.
Thyroid : official journal of the American Thyroid Association 2001;11(7):629-36.
2001: Norisato Mitsutake; Hiroyuki Namba; SS Shklyaev; T Tsukazaki; Akira Ohtsuru; M Ohba; T Kuroki; H Ayabe; Shunichi Yamashita
PKC delta mediates ionizing radiation-induced activation of c-Jun NH(2)-terminal kinase through MKK7 in human thyroid cells.
Oncogene 2001;20(8):989-96.
2001: K Hamasaki; Masahiro Nakashima; S Naito; Y Akiyama; Akira Ohtsuru; Y Hamanaka; Chao-Tien Hsu; Masahiro Ito; Ichiro Sekine
The sympathetic nervous system promotes carbon tetrachloride-induced liver cirrhosis in rats by suppressing apoptosis and enhancing the growth kinetics of regenerating hepatocytes.
Journal of gastroenterology 2001;36(2):111-20.
2000: Vera Braiden; Akira Ohtsuru; Yujo Kawashita; Fumio Miki; T Sawada; M Ito; Y Cao; Yasufumi Kaneda; T Koji; Shunichi Yamashita
Eradication of breast cancer xenografts by hyperthermic suicide gene therapy under the control of the heat shock protein promoter.
Human gene therapy 2000;11(18):2453-63.
2000: Yujo Kawashita; Akira Ohtsuru; Hikaru Fujioka; Yukio Kamohara; Y Kawazoe; N Sugiyama; Susumu Eguchi; H Kuroda; Junichiro Furui; S Yamashita; Y Kaneda; Takashi Kanematsu
Safe and efficient gene transfer into porcine hepatocytes using Sendai virus-cationic liposomes for bioartificial liver support.
Artificial organs 2000;24(12):932-8.
2000: Hiroshi Ishihara; H Yoshimoto; M Fujioka; R Murakami; Akiyoshi Hirano; Tohru Fujii; Akira Ohtsuru; H Namba; Shunichi Yamashita
Keloid fibroblasts resist ceramide-induced apoptosis by overexpression of insulin-like growth factor I receptor.
The Journal of investigative dermatology 2000;115(6):1065-71.
2000: K Akino; Akira Ohtsuru; K Kanda; A Yasuda; T Yamamoto; Y Akino; S Naito; M Kurokawa; N Iwahori; Shunichi Yamashita
Parathyroid hormone-related peptide is a potent tumor angiogenic factor.
Endocrinology 2000;141(11):4313-6.
2000: Sautin Yuri; Noboru Takamura; SS Shklyaev; Y Nagayama; Akira Ohtsuru; Hiroyuki Namba; Shunichi Yamashita
Ceramide-induced apoptosis of human thyroid cancer cells resistant to apoptosis by irradiation.
Thyroid : official journal of the American Thyroid Association 2000;10(9):733-40.
2000: Akira Ohtsuru; H Yoshimoto; H Ishihara; Hiroyuki Namba; Shunichi Yamashita
Insulin-like growth factor-I (IGF-I)/IGF-I receptor axis and increased invasion activity of fibroblasts in keloid.
Endocrine journal 2000;47 Suppl():S41-4.
2000: SS Shklyaev; Hiroyuki Namba; T Hara; Akira Ohtsuru; Shunichi Yamashita
Sage transcript profiles in cultured human fetal fibroblasts, WI-38.
DNA sequence : the journal of DNA sequencing and mapping 2000;11(3-4):281-6.
1999: Akihiko Yonekura; Makoto Osaki; Y Hirota; T Tsukazaki; Y Miyazaki; Tomoko Matsumoto; Akira Ohtsuru; Hiroyuki Namba; Hiroyuki Shindo; Shunichi Yamashita
Transforming growth factor-beta stimulates articular chondrocyte cell growth through p44/42 MAP kinase (ERK) activation.
Endocrine journal 1999;46(4):545-53.
1999: S Nakamura; Akira Ohtsuru; N Takamura; Gaspar Kitange; Yoshiharu Tokunaga; A Yasunaga; Shobu Shibata; S Yamashita
Prop-1 gene expression in human pituitary tumors.
The Journal of clinical endocrinology and metabolism 1999;84(7):2581-4.
1999: Yujo Kawashita; Akira Ohtsuru; Y Kaneda; Y Nagayama; Y Kawazoe; S Eguchi; H Kuroda; H Fujioka; M Ito; Takashi Kanematsu; Shunichi Yamashita
Regression of hepatocellular carcinoma in vitro and in vivo by radiosensitizing suicide gene therapy under the inducible and spatial control of radiation.
Human gene therapy 1999;10(9):1509-19.
1999: T Ito; Masahiro Ito; S Naito; Akira Ohtsuru; Y Nagayama; T Kanematsu; S Yamashita; Ichiro Sekine
Expression of the Axl receptor tyrosine kinase in human thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association 1999;9(6):563-7.
1999: K Okano; T Usa; Akira Ohtsuru; T Tsukazaki; Y Miyazaki; Akihiko Yonekura; Hiroyuki Namba; H Shindoh; Shunichi Yamashita
Effect of 22-oxa-1,25-dihydroxyvitamin D3 on human thyroid cancer cell growth.
Endocrine journal 1999;46(2):243-52.
1999: H Yoshimoto; Hiroshi Ishihara; Akira Ohtsuru; K Akino; R Murakami; H Kuroda; H Namba; M Ito; Tohru Fujii; Shunichi Yamashita
Overexpression of insulin-like growth factor-1 (IGF-I) receptor and the invasiveness of cultured keloid fibroblasts.
The American journal of pathology 1999;154(3):883-9.
1999: M Nishihara; M Ito; Tsutomu Tomioka; Akira Ohtsuru; T Taguchi; Takashi Kanematsu
Clinicopathological implications of parathyroid hormone-related protein in human colorectal tumours.
The Journal of pathology 1999;187(2):217-22.
1998: K Akino; Akira Ohtsuru; M Nakashima; M Ito; Y Ting-Ting; Vera Braiden; T Kawawaki; J Baba; Shunichi Yamashita; N Iwahori
Distribution of the parathyroid hormone-related peptide and its receptor in the saccus vasculosus and choroid plexus in the red stingray (Dasyatis akajei: Elasmobranch).
Cellular and molecular neurobiology 1998;18(3):361-8.
1997: GK Alipov; M Ito; M Nakashima; Y Ikeda; T Nakayama; Akira Ohtsuru; Shunichi Yamashita; I Sekine
Expression of parathyroid hormone-related peptide (PTHrP) in gastric tumours.
The Journal of pathology 1997;182(2):174-9.
1997: M Ito; M Nakashima; GK Alipov; S Matsuzaki; Akira Ohtsuru; H Yano; Shunichi Yamashita; I Sekine
Gastric cancer associated with overexpression of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor in relation to tumor progression.
Journal of gastroenterology 1997;32(3):396-400.
1997: M Ito; Akira Ohtsuru
[PTH/PTHrP receptor].
Nihon rinsho. Japanese journal of clinical medicine 1997;55 Suppl 2():495-8.
1997: K Okano; T Tsukazaki; Akira Ohtsuru; Makoto Osaki; Akihiko Yonekura; K Iwasaki; Shunichi Yamashita
Expression of parathyroid hormone-related peptide in human osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1997;15(2):175-80.
1996: T Nakayama; M Ito; Akira Ohtsuru; S Naito; M Nakashima; James A Fagin; S Yamashita; I Sekine
Expression of the Ets-1 proto-oncogene in human gastric carcinoma: correlation with tumor invasion.
The American journal of pathology 1996;149(6):1931-9.
1996: K Okano; T Tsukazaki; Akira Ohtsuru; Hiroyuki Namba; Makoto Osaki; K Iwasaki; S Yamashita
Parathyroid hormone-related peptide in synovial fluid and disease activity of rheumatoid arthritis.
British journal of rheumatology 1996;35(11):1056-62.
1996: K Motomura; Akira Ohtsuru; H Enomoto; T Tsukazaki; Hiroyuki Namba; Y Tsuji; S Yamashita
Osteogenic action of parathyroid hormone-related peptide (1-141) in rat ROS cells.
Endocrine journal 1996;43(5):527-35.
1996: M Nakashima; M Ito; Akira Ohtsuru; G K Alipov; S Matsuzaki; T Nakayama; S Yamashita; I Sekine
Expression of parathyroid hormone (PTH)-related peptide (PTHrP) and PTH/PTHrP receptor in giant cell tumour of tendon sheath.
The Journal of pathology 1996;180(1):80-4.
1996: T Tsukazaki; Akira Ohtsuru; Hiroyuki Namba; J Oda; K Motomura; Makoto Osaki; T Kiriyama; K Iwasaki; S Yamashita
Parathyroid hormone-related protein (PTHrP) action in rat articular chondrocytes: comparison of PTH(1-34), PTHrP(1-34), PTHrP(1-141), PTHrP(100-114) and antisense oligonucleotides against PTHrP.
The Journal of endocrinology 1996;150(3):359-68.
1996: K Akino; Akira Ohtsuru; H Yano; S Ozeki; Hiroyuki Namba; M Nakashima; M Ito; T Matsumoto; S Yamashita
Antisense inhibition of parathyroid hormone-related peptide gene expression reduces malignant pituitary tumor progression and metastases in the rat.
Cancer research 1996;56(1):77-86.
1995: T Tsukazaki; Akira Ohtsuru; H Enomoto; H Yano; K Motomura; M Ito; Hiroyuki Namba; K Iwasaki; S Yamashita
Expression of parathyroid hormone-related protein in rat articular cartilage.
Calcified tissue international 1995;57(3):196-200.
1995: C Hosoda; Akira Ohtsuru; Hiroyuki Namba; K Motomura; T Hara; M Nakashima; M Ito; K Yokoro; S Yamashita
Establishment and characterization of a malignant epithelioid hemangioendothelioma from mouse thyroid tumor.
Endocrine journal 1995;42(3):341-50.
1995: M Nakashima; Akira Ohtsuru; W T Luo; T Nakayama; H Enomoto; T Usa; T Kiriyama; M Ito; S Nagataki; S Yamashita
Expression of parathyroid hormone-related peptide in human thyroid tumours.
The Journal of pathology 1995;175(2):227-36.
1995: S Nagataki; M Nakashima; K Akino; Akira Ohtsuru; Hiroyuki Namba; T Kiriyama; M Ito; I Sekine; S Yamashita
Parathyroid hormone-related peptide expression in endocrine tumors.
Mineral and electrolyte metabolism 1995;21(1-3):148-51.
1994: T Tsukazaki; T Matsumoto; H Enomoto; T Usa; Akira Ohtsuru; Hiroyuki Namba; K Iwasaki; S Yamashita
Growth hormone directly and indirectly stimulates articular chondrocyte cell growth.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1994;2(4):259-67.
1994: T Tsukazaki; T Usa; T Matsumoto; H Enomoto; Akira Ohtsuru; Hiroyuki Namba; K Iwasaki; S Yamashita
Effect of transforming growth factor-beta on the insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes.
Experimental cell research 1994;215(1):9-16.
1994: T Usa; T Tsukazaki; Hiroyuki Namba; Akira Ohtsuru; H Kimura; M C Villadolid; S Nagataki; S Yamashita
Correlation between suppression of c-myc and antiproliferative effect of transforming growth factor-beta 1 in thyroid carcinoma cell growth.
Endocrinology 1994;135(4):1378-84.
1994: T Tsutsumi; Akio Ido; Kazuhiko Nakao; Keisuke Hamasaki; Yuji Kato; Akira Ohtsuru; Keisuke Nakata; T Tamaoki; S Nagataki
Reciprocal regulation of alpha-fetoprotein and albumin gene expression by butyrate in human hepatoma cells.
Gastroenterology 1994;107(2):499-504.
1994: T Nakayama; Akira Ohtsuru; H Enomoto; Hiroyuki Namba; S Ozeki; Y Shibata; T Yokota; M Nobuyoshi; M Ito; I Sekine
Coronary atherosclerotic smooth muscle cells overexpress human parathyroid hormone-related peptides.
Biochemical and biophysical research communications 1994;200(2):1028-35.
1994: M Ito; Akira Ohtsuru; H Enomoto; S Ozeki; M Nakashima; T Nakayama; K Shichijo; I Sekine; S Yamashita
Expression of parathyroid hormone-related peptide in relation to perturbations of gastric motility in the rat.
Endocrinology 1994;134(4):1936-42.
1993: M Ito; H Enomoto; T Usa; M C Villadolid; Akira Ohtsuru; Hiroyuki Namba; I Sekine; S Yamashita
Expression of parathyroid hormone related peptide in human pituitary tumours.
Journal of clinical pathology 1993;46(7):682-3.
1993: H Imamura; I Morimoto; S Etoh; T Usa; Hiroyuki Namba; Akira Ohtsuru; A Yokota; S Nagataki; S Yamashita
Skeletal muscle glucose transporter gene expression is not affected by injecting growth-hormone-secreting cells in young rats.
Diabetologia 1993;36(6):475-80.
1993: H Enomoto; S Yamashita; T Usa; Hiroyuki Namba; Akira Ohtsuru; M C Villadolid; T Tsukazaki; T Matsumoto; K Iwasaki
Autocrine/paracrine function of parathyroid hormone-related peptide in rat osteoblast-like cells.
Biochemical and biophysical research communications 1993;191(3):1261-9.
1992: M Hatano; Keisuke Nakata; Kazuhiko Nakao; T Tsutsumi; Akira Ohtsuru; T Nakamura; T Tamaoki; S Nagataki
Hepatocyte growth factor down-regulates the alpha-fetoprotein gene expression in PLC/PRF/5 human hepatoma cells.
Biochemical and biophysical research communications 1992;189(1):385-91.
1991: Kazuhiko Nakao; Keisuke Nakata; S Mitsuoka; Akira Ohtsuru; Akio Ido; M Hatano; Y Sato; T Nakayama; M Shima; Y Kusumoto
Transforming growth factor beta 1 differentially regulates alpha-fetoprotein and albumin in HuH-7 human hepatoma cells.
Biochemical and biophysical research communications 1991;174(3):1294-9.