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Nikos Oikonomakos

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
31
Leonidas, Demetres
26
Johnson, Louise
21
Zographos, Spyros
17
Chrysina, Evangelia
16
Acharya, Ravi
13
Skamnaki, Vicky
11
Kosmopoulou, Magda
9
Papageorgiou, Anastassios
9
Tiraidis, Costas
9
Watson, Kimberly
8
Tsitsanou, Katerina
8
Fleet, George
6
Barford, David
6
Archontis, Georgios
4
Docsa, Tibor

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Publications

TOP 3
Benltifa Mahmoud; Hayes Joseph M; Vidal Sébastien; Gueyrard David; Goekjian Peter G; Praly Jean-Pierre; Kizilis Gregory; Tiraidis Costas; Alexacou Kyra-Melinda; Chrysina Evangelia D; Zographos Spyros E; Leonidas Demetres D; Archontis Georgios; Oikonomakos Nikos G
Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors.
Samanta Anirban; Leonidas Demetres D; Dasgupta Swagata; Pathak Tanmaya; Zographos Spyros E; Oikonomakos Nikos G
Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation.
Vénien-Bryan Catherine; Jonic Slavica; Skamnaki Vasiliki; Brown Nick; Bischler Nicolas; Oikonomakos Nikos G; Boisset Nicolas; Johnson Louise N
The structure of phosphorylase kinase holoenzyme at 9.9 angstroms resolution and location of the catalytic subunit and the substrate glycogen phosphorylase.

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All Publications

2009: Benltifa Mahmoud; Hayes Joseph M; Vidal Sébastien; Gueyrard David; Goekjian Peter G; Praly Jean-Pierre; Kizilis Gregory; Tiraidis Costas; Alexacou Kyra-Melinda; Chrysina Evangelia D; Zographos Spyros E; Leonidas Demetres D; Archontis Georgios; Oikonomakos Nikos G
Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors.
Bioorganic & medicinal chemistry 2009;17(20):7368-80.
2009: Samanta Anirban; Leonidas Demetres D; Dasgupta Swagata; Pathak Tanmaya; Zographos Spyros E; Oikonomakos Nikos G
Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation.
Journal of medicinal chemistry 2009;52(4):932-42.
2009: Vénien-Bryan Catherine; Jonic Slavica; Skamnaki Vasiliki; Brown Nick; Bischler Nicolas; Oikonomakos Nikos G; Boisset Nicolas; Johnson Louise N
The structure of phosphorylase kinase holoenzyme at 9.9 angstroms resolution and location of the catalytic subunit and the substrate glycogen phosphorylase.
Structure (London, England : 1993) 2009;17(1):117-27.
2008: Wen Xiaoan; Sun Hongbin; Liu Jun; Cheng Keguang; Zhang Pu; Zhang Liying; Hao Jia; Zhang Luyong; Ni Peizhou; Zographos Spyros E; Leonidas Demetres D; Alexacou Kyra-Melinda; Gimisis Thanasis; Hayes Joseph M; Oikonomakos Nikos G
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
Journal of medicinal chemistry 2008;51(12):3540-54.
2008: Alexacou Kyra-Melinda; Hayes Joseph M; Tiraidis Costas; Zographos Spyros E; Leonidas Demetres D; Chrysina Evangelia D; Archontis Georgios; Oikonomakos Nikos G; Paul Jashuva V; Varghese Babu; Loganathan Duraikkannu
Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
Proteins 2008;71(3):1307-23.
2008: Oikonomakos Nikos G; Somsák László
Advances in glycogen phosphorylase inhibitor design.
Current opinion in investigational drugs (London, England : 2000) 2008;9(4):379-95.
2008: Li Hongqing; Liu Tao; Zhang Yongmin; Favre Sylvain; Bello Claudia; Vogel Pierre; Butters Terry D; Oikonomakos Nikos G; Marrot Jérôme; Blériot Yves
New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase.
Chembiochem : a European journal of chemical biology 2008;9(2):253-60.
2007: Tiraidis Costas; Alexacou Kyra-Melinda; Zographos Spyros E; Leonidas Demetres D; Gimisis Thanasis; Oikonomakos Nikos G
FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase.
Protein science : a publication of the Protein Society 2007;16(8):1773-82.
2007: Leonidas Demetres D; Swamy Bale M; Hatzopoulos George N; Gonchigar Sathisha J; Chachadi Vishwanath B; Inamdar Shashikala R; Zographos Spyros E; Oikonomakos Nikos G
Structural basis for the carbohydrate recognition of the Sclerotium rolfsii lectin.
Journal of molecular biology 2007;368(4):1145-61.
2007: Polydoridis Savvas; Leonidas Demetres D; Oikonomakos Nikos G; Archontis Georgios
Recognition of ribonuclease A by 3'-5'-pyrophosphate-linked dinucleotide inhibitors: a molecular dynamics/continuum electrostatics analysis.
Biophysical journal 2007;92(5):1659-72.
2007: Birch Alan M; Kenny Peter W; Oikonomakos Nikos G; Otterbein Ludovic; Schofield Paul; Whittamore Paul R O; Whalley Dave P
Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(2):394-9.
2006: Hampson Laura J; Arden Catherine; Agius Loranne; Ganotidis Minas; Kosmopoulou Magda N; Tiraidis Costas; Elemes Yiannis; Sakarellos Constantinos; Leonidas Demetres D; Oikonomakos Nikos G
Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site.
Bioorganic & medicinal chemistry 2006;14(23):7835-45.
2006: Whittamore Paul R O; Addie Matthew S; Bennett Stuart N L; Birch Alan M; Butters Michael; Godfrey Linda; Kenny Peter W; Morley Andrew D; Murray Paul M; Oikonomakos Nikos G; Otterbein Ludovic R; Pannifer Andrew D; Parker Jeremy S; Readman Kristy; Siedlecki Pawel S; Schofield Paul; Stocker Andy; Taylor Melvyn J; Townsend Linda A; Whalley David P; Whitehouse Jennifer
Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies.
Bioorganic & medicinal chemistry letters 2006;16(21):5567-71.
2006: Oikonomakos Nikos G; Tiraidis Costas; Leonidas Demetres D; Zographos Spyros E; Kristiansen Marit; Jessen Claus U; Nørskov-Lauritsen Leif; Agius Loranne
Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
Journal of medicinal chemistry 2006;49(19):5687-701.
2006: Leonidas Demetres D; Maiti Tushar Kanti; Samanta Anirban; Dasgupta Swagata; Pathak Tanmaya; Zographos Spyros E; Oikonomakos Nikos G
The binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal.
Bioorganic & medicinal chemistry 2006;14(17):6055-64.
2006: Petsalakis Evangelia I; Chrysina Evangelia D; Tiraidis Costas; Hadjiloi Theodoros; Leonidas Demetres D; Oikonomakos Nikos G; Aich Udayanath; Varghese Babu; Loganathan Duraikkannu
Crystallographic studies on N-azidoacetyl-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine.
Bioorganic & medicinal chemistry 2006;14(15):5316-24.
2006: Lukacs Christine M; Oikonomakos Nikos G; Crowther Robert L; Hong Li-Na; Kammlott R Ursula; Levin Wayne; Li Shirley; Liu Chao-Min; Lucas-McGady Debra; Pietranico Sherrie; Reik Linda
The crystal structure of human muscle glycogen phosphorylase a with bound glucose and AMP: an intermediate conformation with T-state and R-state features.
Proteins 2006;63(4):1123-6.
2006: Hadjiloi Theodoros; Tiraidis Costas; Chrysina Evangelia D; Leonidas Demetres D; Oikonomakos Nikos G; Tsipos Panagiotis; Gimisis Thanasis
Binding of oxalyl derivatives of beta-d-glucopyranosylamine to muscle glycogen phosphorylase b.
Bioorganic & medicinal chemistry 2006;14(11):3872-82.
2006: Anagnostou Eleni; Kosmopoulou Magda N; Chrysina Evangelia D; Leonidas Demetres D; Hadjiloi Theodoros; Tiraidis Costantinos; Zographos Spyros E; Györgydeák Zoltán; Somsák László; Docsa Tibor; Gergely Pál; Kolisis Fragiskos N; Oikonomakos Nikos G
Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase.
Bioorganic & medicinal chemistry 2006;14(1):181-9.
2005: Archontis G; Watson K A; Xie Q; Andreou G; Chrysina E D; Zographos S E; Oikonomakos N G; Karplus M
Glycogen phosphorylase inhibitors: a free energy perturbation analysis of glucopyranose spirohydantoin analogues.
Proteins 2005;61(4):984-98.
2005: Watson Kimberly A; Chrysina Evangelia D; Tsitsanou Katerina E; Zographos Spyros E; Archontis Georgios; Fleet George W J; Oikonomakos Nikos G
Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins 2005;61(4):966-83.
2005: Klabunde Thomas; Wendt K Ulrich; Kadereit Dieter; Brachvogel Volker; Burger Hans-Jörg; Herling Andreas W; Oikonomakos Nikos G; Kosmopoulou Magda N; Schmoll Dieter; Sarubbi Edoardo; von Roedern Erich; Schönafinger Karl; Defossa Elisabeth
Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes.
Journal of medicinal chemistry 2005;48(20):6178-93.
2005: Hatzopoulos George N; Leonidas Demetres D; Kardakaris Rozina; Kobe Joze; Oikonomakos Nikos G
The binding of IMP to ribonuclease A.
The FEBS journal 2005;272(15):3988-4001.
2005: Oikonomakos Nikos G; Kosmopoulou Magda N; Chrysina Evangelia D; Leonidas Demetres D; Kostas Ioannis D; Wendt K Ulrich; Klabunde Thomas; Defossa Elisabeth
Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.
Protein science : a publication of the Protein Society 2005;14(7):1760-71.
2005: Chrysina Evangelia D; Kosmopoulou Magda N; Tiraidis Constantinos; Kardakaris Rozina; Bischler Nicolas; Leonidas Demetres D; Hadady Zsuzsa; Somsak Laszlo; Docsa Tibor; Gergely Pal; Oikonomakos Nikos G
Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.
Protein science : a publication of the Protein Society 2005;14(4):873-88.
2005: Chrysina Evangelia D; Kosmopoulou Magda N; Kardakaris Rozina; Bischler Nicolas; Leonidas Demetres D; Kannan Thanukrishnan; Loganathan Duraikkannu; Oikonomakos Nikos G
Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies.
Bioorganic & medicinal chemistry 2005;13(3):765-72.
2004: Kosmopoulou Magda N; Leonidas Demetres D; Chrysina Evangelia D; Bischler Nicolas; Eisenbrand Gerhard; Sakarellos Constantinos E; Pauptit Richard; Oikonomakos Nikos G
Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex.
European journal of biochemistry / FEBS 2004;271(11):2280-90.
2003: Leonidas Demetres D; Chavali Gayatri B; Oikonomakos Nikos G; Chrysina Evangelia D; Kosmopoulou Magda N; Vlassi Metaxia; Frankling Claire; Acharya K Ravi
High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors.
Protein science : a publication of the Protein Society 2003;12(11):2559-74.
2003: Pinotsis Nikos; Leonidas Demetres D; Chrysina Evangelia D; Oikonomakos Nikos G; Mavridis Irene M
The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: kinetic and crystallographic studies.
Protein science : a publication of the Protein Society 2003;12(9):1914-24.
2003: Oikonomakos Nikos G; Chrysina Evangelia D; Kosmopoulou Magda N; Leonidas Demetres D
Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution.
Biochimica et biophysica acta 2003;1647(1-2):325-32.
2003: Leonidas Demetres D; Swamy Bale M; Bhat Anuradha G; Inamdar Shashikala R; Kosmopoulou Magda N; Chrysina Evangelia D; Oikonomakos Nikos G
Crystallization and preliminary X-ray crystallographic analysis of Sclerotium rolfsii lectin.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 2):363-5.
2002: Oikonomakos Nikos G
Glycogen phosphorylase as a molecular target for type 2 diabetes therapy.
Current protein & peptide science 2002;3(6):561-86.
2002: Cook A; Lowe E D; Chrysina E D; Skamnaki V T; Oikonomakos N G; Johnson L N
Structural studies on phospho-CDK2/cyclin A bound to nitrate, a transition state analogue: implications for the protein kinase mechanism.
Biochemistry 2002;41(23):7301-11.
2002: Oikonomakos Nikos G; Zographos Spyros E; Skamnaki Vicky T; Archontis Georgios
The 1.76 A resolution crystal structure of glycogen phosphorylase B complexed with glucose, and CP320626, a potential antidiabetic drug.
Bioorganic & medicinal chemistry 2002;10(5):1313-9.
2002: Oikonomakos Nikos G; Kosmopoulou Magda; Zographos Spyros E; Leonidas Demetres D; Chrysina Evangelia D; Somsák László; Nagy Veronika; Praly Jean-Pierre; Docsa Tibor; Tóth Béla; Gergely Pál
Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.
European journal of biochemistry / FEBS 2002;269(6):1684-96.
2002: Oikonomakos Nikos G; Skamnaki Vicky T; Osz Erzsébet; Szilágyi László; Somsák László; Docsa Tibor; Tóth Béla; Gergely Pál
Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase B.
Bioorganic & medicinal chemistry 2002;10(2):261-8.
2001: Poulas K; Eliopoulos E; Vatzaki E; Navaza J; Kontou M; Oikonomakos N; Acharya K R; Tzartos S J
Crystal structure of Fab198, an efficient protector of the acetylcholine receptor against myasthenogenic antibodies.
European journal of biochemistry / FEBS 2001;268(13):3685-93.
2000: Tsitsanou K E; Skamnaki V T; Oikonomakos N G
Structural basis of the synergistic inhibition of glycogen phosphorylase a by caffeine and a potential antidiabetic drug.
Archives of biochemistry and biophysics 2000;384(2):245-54.
2000: Oikonomakos N G; Schnier J B; Zographos S E; Skamnaki V T; Tsitsanou K E; Johnson L N
Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site.
The Journal of biological chemistry 2000;275(44):34566-73.
2000: Skamnaki V T; Oikonomakos N G
Kinetic characterization of the double mutant R148A/E182S of glycogen phosphorylase kinase catalytic subunit: the role of the activation loop.
Journal of protein chemistry 2000;19(6):499-505.
2000: Oikonomakos N G; Skamnaki V T; Tsitsanou K E; Gavalas N G; Johnson L N
A new allosteric site in glycogen phosphorylase b as a target for drug interactions.
Structure (London, England : 1993) 2000;8(6):575-84.
2000: Kontou M; Leonidas D D; Vatzaki E H; Tsantili P; Mamalaki A; Oikonomakos N G; Acharya K R; Tzartos S J
The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor.
European journal of biochemistry / FEBS 2000;267(8):2389-97.
1999: Skamnaki V T; Owen D J; Noble M E; Lowe E D; Lowe G; Oikonomakos N G; Johnson L N
Catalytic mechanism of phosphorylase kinase probed by mutational studies.
Biochemistry 1999;38(44):14718-30.
1999: Oikonomakos N G; Tsitsanou K E; Zographos S E; Skamnaki V T; Goldmann S; Bischoff H
Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate.
Protein science : a publication of the Protein Society 1999;8(10):1930-45.
1999: Tsitsanou K E; Oikonomakos N G; Zographos S E; Skamnaki V T; Gregoriou M; Watson K A; Johnson L N; Fleet G W
Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure.
Protein science : a publication of the Protein Society 1999;8(4):741-9.
1998: Gregoriou M; Noble M E; Watson K A; Garman E F; Krulle T M; de la Fuente C; Fleet G W; Oikonomakos N G; Johnson L N
The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.
Protein science : a publication of the Protein Society 1998;7(4):915-27.
1997: Zographos S E; Oikonomakos N G; Tsitsanou K E; Leonidas D D; Chrysina E D; Skamnaki V T; Bischoff H; Goldmann S; Watson K A; Johnson L N
The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor.
Structure (London, England : 1993) 1997;5(11):1413-25.
1997: Lowe E D; Noble M E; Skamnaki V T; Oikonomakos N G; Owen D J; Johnson L N
The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition.
The EMBO journal 1997;16(22):6646-58.
1996: Oikonomakos N G; Zographos S E; Tsitsanou K E; Johnson L N; Acharya K R
Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal.
Protein science : a publication of the Protein Society 1996;5(12):2416-28.
1996: Kontou M; Vatzaki E H; Kokla A; Acharya K R; Oikonomakos N G; Tzartos S J
Characterisation, crystallisation and preliminary X-ray diffraction analysis of a Fab fragment of a rat monoclonal antibody with very high affinity for the human muscle acetylcholine receptor.
FEBS letters 1996;389(2):195-8.
1996: Mitchell E P; Withers S G; Ermert P; Vasella A T; Garman E F; Oikonomakos N G; Johnson L N
Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry 1996;35(23):7341-55.
1995: Oikonomakos N G; Kontou M; Zographos S E; Watson K A; Johnson L N; Bichard C J; Fleet G W; Acharya K R
N-acetyl-beta-D-glucopyranosylamine: a potent T-state inhibitor of glycogen phosphorylase. A comparison with alpha-D-glucose.
Protein science : a publication of the Protein Society 1995;4(12):2469-77.
1995: Oikonomakos N G; Zographos S E; Johnson L N; Papageorgiou A C; Acharya K R
The binding of 2-deoxy-D-glucose 6-phosphate to glycogen phosphorylase b: kinetic and crystallographic studies.
Journal of molecular biology 1995;254(5):900-17.
1995: Zographos S E; Oikonomakos N G; Dixon H B; Griffin W G; Johnson L N; Leonidas D D
Sulphate-activated phosphorylase b: the pH-dependence of catalytic activity.
The Biochemical journal 1995;310 ( Pt 2)():565-70.
1995: Watson K A; Mitchell E P; Johnson L N; Cruciani G; Son J C; Bichard C J; Fleet G W; Oikonomakos N G; Kontou M; Zographos S E
Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection.
Acta crystallographica. Section D, Biological crystallography 1995;51(Pt 4):458-72.
1994: Oikonomakos N G; Kontou M; Zographos S E; Tsitoura H S; Johnson L N; Watson K A; Mitchell E P; Fleet G W; Son J C; Bichard C J
The design of potential antidiabetic drugs: experimental investigation of a number of beta-D-glucose analogue inhibitors of glycogen phosphorylase.
European journal of drug metabolism and pharmacokinetics 1994;19(3):185-92.
1994: Watson K A; Mitchell E P; Johnson L N; Son J C; Bichard C J; Orchard M G; Fleet G W; Oikonomakos N G; Leonidas D D; Kontou M
Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.
Biochemistry 1994;33(19):5745-58.
1993: Vatzaki E H; Acharya K R; Oikonomakos N G; Tzartos S J
Crystallization and preliminary crystallographic study of an Fab fragment of a pathogenic rat monoclonal antibody against the nicotinic acetylcholine receptor.
Protein science : a publication of the Protein Society 1993;2(10):1770-2.
1993: Johnson L N; Snape P; Martin J L; Acharya K R; Barford D; Oikonomakos N G
Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase b.
Journal of molecular biology 1993;232(1):253-67.
1992: Leonidas D D; Oikonomakos N G; Papageorgiou A C; Sotiroudis T G
Kinetic properties of tetrameric glycogen phosphorylase b in solution and in the crystalline state.
Protein science : a publication of the Protein Society 1992;1(9):1123-32.
1992: Leonidas D D; Oikonomakos N G; Papageorgiou A C; Acharya K R; Barford D; Johnson L N
Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate.
Protein science : a publication of the Protein Society 1992;1(9):1112-22.
1991: Martin J L; Veluraja K; Ross K; Johnson L N; Fleet G W; Ramsden N G; Bruce I; Orchard M G; Oikonomakos N G; Papageorgiou A C
Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes.
Biochemistry 1991;30(42):10101-16.
1991: Papageorgiou A C; Oikonomakos N G; Leonidas D D; Bernet B; Beer D; Vasella A
The binding of D-gluconohydroximo-1,5-lactone to glycogen phosphorylase. Kinetic, ultracentrifugation and crystallographic studies.
The Biochemical journal 1991;274 ( Pt 2)():329-38.
1991: Leonidas D D; Oikonomakos N G; Papageorgiou A C
Sulphate activates phosphorylase b by binding to the Ser (P) site.
Biochimica et biophysica acta 1991;1076(2):305-7.
1990: Leonidas D D; Oikonomakos N G; Papageorgiou A C; Xenakis A; Cazianis C T; Bem F
The ammonium sulfate activation of phosphorylase b.
FEBS letters 1990;261(1):23-7.
1989: Papageorgiou A C; Oikonomakos N G; Leonidas D D
Inhibition of rabbit muscle glycogen phosphorylase by D-gluconohydroximo-1,5-lactone-N-phenylurethane.
Archives of biochemistry and biophysics 1989;272(2):376-85.
1989: Oikonomakos N G; Acharya K R; Melpidou A E; Stuart D I; Johnson L N
The binding of beta-glycerophosphate to glycogen phosphorylase b in the crystal.
Archives of biochemistry and biophysics 1989;270(1):62-8.
1988: Barford D; Schwabe J W; Oikonomakos N G; Acharya K R; Hajdu J; Papageorgiou A C; Martin J L; Knott J C; Vasella A; Johnson L N
Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the beta-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane.
Biochemistry 1988;27(18):6733-41.
1988: Oikonomakos N G; Acharya K R; Stuart D I; Melpidou A E; McLaughlin P J; Johnson L N
Uridine(5')diphospho(1)-alpha-D-glucose. A binding study to glycogen phosphorylase b in the crystal.
European journal of biochemistry / FEBS 1988;173(3):569-78.
1987: Oikonomakos N G; Johnson L N; Acharya K R; Stuart D I; Barford D; Hajdu J; Varvill K M; Melpidou A E; Papageorgiou T; Graves D J
Pyridoxal phosphate site in glycogen phosphorylase b: structure in native enzyme and in three derivatives with modified cofactors.
Biochemistry 1987;26(25):8381-9.
1987: Johnson L N; Acharya K R; Stuart D I; Barford D; Oikonomakos N G; Hajdu J; Varvill K M
Phosphate-recognition sites in catalysis and control of glycogen phosphorylase b.
Biochemical Society transactions 1987;15(5):1001-5.
1987: Hajdu J; Acharya K R; Stuart D I; McLaughlin P J; Barford D; Oikonomakos N G; Klein H; Johnson L N
Catalysis in the crystal: synchrotron radiation studies with glycogen phosphorylase b.
The EMBO journal 1987;6(2):539-46.
1985: Oikonomakos N G; Melpidou A E; Johnson L N
Crystallization of pig skeletal phosphorylase b. Purification, physical and catalytic characterization.
Biochimica et biophysica acta 1985;832(3):248-56.
1984: Melpidou A E; Oikonomakos N G; Evangelopoulos A E
The effect of ligands on the glucose-6-P activation and dissociation of phosphorylase a.
Progress in clinical and biological research 1984;144A():223-32.
1984: Sotiroudis T G; Oikonomakos N G; Evangelopoulos A E
Irreversible dissociation of pyridoxal 5'-phosphate from glycogen phosphorylase by sulphated polysaccharides.
Progress in clinical and biological research 1984;144A():181-93.
1983: Melpidou A E; Oikonomakos N G
Effect of glucose-6-P on the catalytic and structural properties of glycogen phosphorylase a.
FEBS letters 1983;154(1):105-10.
1983: Sotiroudis T G; Cazianis C T; Oikonomakos N G; Evangelopoulos A E
Effect of sodium cholate on the catalytic and structural properties of phosphorylase b.
European journal of biochemistry / FEBS 1983;131(3):625-31.
1982: Ktenas T B; Oikonomakos N G; Sotiroudis T G; Nikolaropoulos S; Evangelopoulos A E
Interaction of aliphatic amines with glycogen phosphorylase.
Journal of biochemistry 1982;92(6):2029-33.
1982: Oikonomakos N G; Sotiroudis T G; Nikolaropoulos S; Melpidou A E; Evangelopoulos A E
Homotropic interactions of phosphorylase with ligands as studied by spectroscopic techniques.
Progress in clinical and biological research 1982;102 Pt C():37-46.
1981: Sotiroudis T G; Oikonomakos N G; Evangelopoulos A E
Effect of prostaglandins on phosphorylase b.
Biochimica et biophysica acta 1981;658(2):270-9.
1980: Ktenas T B; Oikonomakos N G; Sotiroudis T G; Nikolaropoulos S I; Evangelopoulos A E
Effect of polymyxins on glycogen phosphorylase.
Biochemical and biophysical research communications 1980;97(2):415-22.

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