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Hyun Ok

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Lin Chu; Lawrence F Colwell; Jisong Cui; Jilly Evans; Amy Galka; Mark T Goulet; Nancy Hayes; Jane Lo; John Menke; Hyun O Ok; Debra L Ondeyka; Minal Patel; Grace M Quaker; Heather Sings; Helen M Armstrong; Linda L Chang; Amy F Cheng; Stephanie L Witkin; Annie Zhao; Feroze Ujjainwalla
Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors.
Scott B Hoyt; Clare London; Hyun O Ok; Edward Gonzalez; Joseph L Duffy; Catherine Abbadie; Brian Dean; John P Felix; Maria L Garcia; Nina Jochnowitz; Bindhu V Karanam; Xiaohua Li; Kathryn A Lyons; Erin McGowan; D Euan MacIntyre; William J Martin; Birgit T Priest; McHardy Smith; Richard A Tschirret-Guth; Vivien A Warren; Brande S Williams; Gregory J Kaczorowski; William H Parsons
Benzazepinone Nav1.7 blockers: potential treatments for neuropathic pain.
George R Lankas; Barbara Leiting; Ranabir Sinha Roy; George J Eiermann; Maria G Beconi; Szalkowski Deborah; Chi-Chung Chan; Scott D Edmondson; William P Feeney; Huaibing He; Dawn E Ippolito; Dooseop Kim; Kathryn A Lyons; Hyun O Ok; Reshma A Patel; Aleksandr N Petrov; Kelly Ann Pryor; Xiaoxia Qian; Leah Reigle; Andrea Woods; Joseph K Wu; Dennis Zaller; Xiaoping Zhang; Lan Zhu; Ann E Weber; Nancy A Thornberry
Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9.

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All Publications

2012: Lin Chu; Lawrence F Colwell; Jisong Cui; Jilly Evans; Amy Galka; Mark T Goulet; Nancy Hayes; Jane Lo; John Menke; Hyun O Ok; Debra L Ondeyka; Minal Patel; Grace M Quaker; Heather Sings; Helen M Armstrong; Linda L Chang; Amy F Cheng; Stephanie L Witkin; Annie Zhao; Feroze Ujjainwalla
Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors.
Bioorganic & medicinal chemistry letters 2012;22(12):4133-8.
2007: Scott B Hoyt; Clare London; Hyun O Ok; Edward Gonzalez; Joseph L Duffy; Catherine Abbadie; Brian Dean; John P Felix; Maria L Garcia; Nina Jochnowitz; Bindhu V Karanam; Xiaohua Li; Kathryn A Lyons; Erin McGowan; D Euan MacIntyre; William J Martin; Birgit T Priest; McHardy Smith; Richard A Tschirret-Guth; Vivien A Warren; Brande S Williams; Gregory J Kaczorowski; William H Parsons
Benzazepinone Nav1.7 blockers: potential treatments for neuropathic pain.
Bioorganic & medicinal chemistry letters 2007;17(22):6172-7.
2005: George R Lankas; Barbara Leiting; Ranabir Sinha Roy; George J Eiermann; Maria G Beconi; Szalkowski Deborah; Chi-Chung Chan; Scott D Edmondson; William P Feeney; Huaibing He; Dawn E Ippolito; Dooseop Kim; Kathryn A Lyons; Hyun O Ok; Reshma A Patel; Aleksandr N Petrov; Kelly Ann Pryor; Xiaoxia Qian; Leah Reigle; Andrea Woods; Joseph K Wu; Dennis Zaller; Xiaoping Zhang; Lan Zhu; Ann E Weber; Nancy A Thornberry
Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9.
Diabetes 2005;54(10):2988-94.
2004: Jinyou Xu; Hyun O Ok; Edward J Gonzalez; Lawrence F Colwell; Bahanu Habulihaz; Huaibing He; Barbara Leiting; Kathryn A Lyons; Frank Marsilio; Reshma A Patel; Joseph K Wu; Nancy A Thornberry; Ann E Weber; Emma R Parmee
Discovery of potent and selective beta-homophenylalanine based dipeptidyl peptidase IV inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(18):4759-62.
2000: Michael J Forrest; Gary J Hom; TJ Bach; Mari Rios Candelore; Margaret A Cascieri; Catherine D Strader; Laurie M Tota; Michael H Fisher; J Szumiloski; Hyun O Ok; Ann E Weber; Matthew J Wyvratt; Pasquale P Vicario; O Marko; L Deng; C Cioffe; B Hegarty-Friscino; E MacIntyre
L-750355, a human beta3-adrenoceptor agonist; in vitro pharmacology and profile of activity in vivo in the rhesus monkey.
European journal of pharmacology 2000;407(1-2):175-81.
2000: Linda L Brockunier; Emma R Parmee; Hyun O Ok; Mari Rios Candelore; Margaret A Cascieri; Lawrence F Colwell; L Deng; William P Feeney; Michael J Forrest; Gary J Hom; D Euan MacIntyre; Laurie M Tota; Matthew J Wyvratt; Michael H Fisher; Ann E Weber
Human beta3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides.
Bioorganic & medicinal chemistry letters 2000;10(18):2111-4.
2000: Hyun O Ok; L B Reigle; Mari Rios Candelore; Margaret A Cascieri; Lawrence F Colwell; L Deng; William P Feeney; Michael J Forrest; Gary J Hom; D Euan MacIntyre; Catherine D Strader; Laurie M Tota; P Wang; Matthew J Wyvratt; Michael H Fisher; Ann E Weber
Substituted oxazole benzenesulfonamides as potent human beta3 adrenergic receptor agonists.
Bioorganic & medicinal chemistry letters 2000;10(14):1531-4.
1999: Emma R Parmee; Elizabeth M Naylor; L Perkins; Vincent J Colandrea; Hyun O Ok; Mari Rios Candelore; Margaret A Cascieri; L Deng; William P Feeney; Michael J Forrest; Gary J Hom; D Euan MacIntyre; Randall R Miller; Ralph A Stearns; Catherine D Strader; Laurie M Tota; Matthew J Wyvratt; Michael H Fisher; Ann E Weber
Human beta3 adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides.
Bioorganic & medicinal chemistry letters 1999;9(5):749-54.
1998: Ann E Weber; Hyun O Ok; Raul Alvaro; Mari Rios Candelore; Margaret A Cascieri; Shuet-Hing Lee Chiu; L Deng; Michael J Forrest; Gary J Hom; JE Hutchins; J Kao; D Euan MacIntyre; Robert J Mathvink; Debra McLoughlin; Randall R Miller; R C Newbold; Timothy V Olah; Emma R Parmee; L Perkins; Ralph A Stearns; Catherine D Strader; J Szumiloski; Yui S Tang; Laurie M Tota; Michael H Fisher
3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic properties.
Bioorganic & medicinal chemistry letters 1998;8(16):2111-6.
1998: Michael H Fisher; A M Amend; TJ Bach; J M Barker; Edward J Brady; Mari Rios Candelore; D Carroll; Margaret A Cascieri; Shuet-Hing Lee Chiu; L Deng; Michael J Forrest; B Hegarty-Friscino; Xiao-Ming Guan; Gary J Hom; JE Hutchins; Linda J Kelly; Robert J Mathvink; Joseph M Metzger; Randall R Miller; Hyun O Ok; Emma R Parmee; Richard Saperstein; Catherine D Strader; Ralph A Stearns; D Euan MacIntyre
A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys.
The Journal of clinical investigation 1998;101(11):2387-93.
1998: Emma R Parmee; Hyun O Ok; Mari Rios Candelore; Laurie M Tota; L Deng; Catherine D Strader; Matthew J Wyvratt; Michael H Fisher; Ann E Weber
Discovery of L-755,507: a subnanomolar human beta 3 adrenergic receptor agonist.
Bioorganic & medicinal chemistry letters 1998;8(9):1107-12.