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Masaaki Oka

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Ryouichi Tsunedomi; Masahito Tsutsui; Kiyoshi Yoshimura; Kazuhiko Sakamoto; Takao Tamesa; Noriaki Hashimoto; Michihisa Iida; Norio Iizuka; Shinsuke Kanekiyo; Masaaki Oka
ABCB6 mRNA and DNA methylation levels serve as useful biomarkers for prediction of early intrahepatic recurrence of hepatitis C virus-related hepatocellular carcinoma.
Ryouichi Tsunedomi; Sawako Harada; Norio Iizuka; Masaaki Oka
Susceptibility of hepatoma-derived cells to histone deacetylase inhibitors is associated with ID2 expression.
Mitsuaki Nishioka; Masaaki Oka; Toshiyuki Okada; Naoko Okayama; Kouhei Sakai; Yutaka Suehiro; Koji Ueno; Rajvir Dahiya; Shoichi Hazama; Hiroshi Hirata; Kohzoh Imai; Yuji Hinoda
Possible involvement of Wnt11 in colorectal cancer progression.

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2013: Ryouichi Tsunedomi; Masahito Tsutsui; Kiyoshi Yoshimura; Kazuhiko Sakamoto; Takao Tamesa; Noriaki Hashimoto; Michihisa Iida; Norio Iizuka; Shinsuke Kanekiyo; Masaaki Oka
ABCB6 mRNA and DNA methylation levels serve as useful biomarkers for prediction of early intrahepatic recurrence of hepatitis C virus-related hepatocellular carcinoma.
International journal of oncology 2013;42(5):1551-9.
2013: Ryouichi Tsunedomi; Sawako Harada; Norio Iizuka; Masaaki Oka
Susceptibility of hepatoma-derived cells to histone deacetylase inhibitors is associated with ID2 expression.
International journal of oncology 2013;42(4):1159-66.
2013: Mitsuaki Nishioka; Masaaki Oka; Toshiyuki Okada; Naoko Okayama; Kouhei Sakai; Yutaka Suehiro; Koji Ueno; Rajvir Dahiya; Shoichi Hazama; Hiroshi Hirata; Kohzoh Imai; Yuji Hinoda
Possible involvement of Wnt11 in colorectal cancer progression.
Molecular carcinogenesis 2013;52(3):207-17.
2012: Shin Kan; Shigeo Koido; Kazunari Maeda; Shoichi Hazama; Sadamu Homma; Yuka Inoue; Masato Okamoto; Masaaki Oka
Suppressive effects of cyclophosphamide and gemcitabine on regulatory T-cell induction in vitro.
Anticancer research 2012;32(12):5363-9.
2012: Chiyo Nakasuga; Shoichi Hazama; Yuka Inoue; Hiroto Matsui; Nobuaki Suzuki; Shigefumi Yoshino; Masaaki Oka
[A patient with intestinal gastrointestinal stromal tumor refractory to molecular targeted but whose quality of life improved after palliative surgery].
Gan to kagaku ryoho. Cancer & chemotherapy 2012;39(12):1902-4.
2012: Yufeng Wang; Shigefumi Yoshino; Xiulian Zhang; Masaaki Oka; Nobuaki Suzuki; Tomio Ueno; Junko K Akada; Norio Iizuka; Yasuhiro Kuramitsu; Kazuyuki Nakamura
Proteomic differential display identifies upregulated vinculin as a possible biomarker of pancreatic cancer.
Oncology reports 2012;28(5):1845-50.
2012: Yufeng Wang; Shigefumi Yoshino; Masaaki Oka; Nobuaki Suzuki; Tomio Ueno; Junko K Akada; Norio Iizuka; Takao Kitagawa; Yasuhiro Kuramitsu; Kazuyuki Nakamura
Glyoxalase I (GLO1) is up-regulated in pancreatic cancerous tissues compared with related non-cancerous tissues.
Anticancer research 2012;32(8):3219-22.
2012: Michihisa Iida; Norio Iizuka; Yoshinari Maeda; Kazuhiko Sakamoto; Takao Tamesa; Yoshihiro Tokuhisa; Ryouichi Tsunedomi; Masahiro Tsutsui; Shin Yoshida; Kiyoshi Yoshimura; Masaaki Oka
Overexpression of the RD RNA binding protein in hepatitis C virus-related hepatocellular carcinoma.
Oncology reports 2012;28(2):728-34.
2012: Masamune Aihara; Kimikazu Hamano; Yutaro Inoue; Hiroko Nishioka; Masaaki Oka; Shigeru Yamamoto; Yoichi Mizukami
Optimizing high-resolution melting analysis for the detection of mutations of GPR30/GPER-1 in breast cancer.
Gene 2012;501(2):118-26.
2012: Masumi Yanagawa; Shigeru Yamamoto; Tomoko Furuya; Kenzo Ikemot; Shigeto Kawauchi; Yukiko Nagashima; Atunori Oga; Masaaki Oka; Kohsuke Sasaki
Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype.
BMC research notes 2012;5():376.
2012: Shigeru Yamamoto; Kiyoshi Yoshimura; Noriko Maeda; Yukiko Nagashima; Michiko Tamesa; Masaaki Oka
Prospective ultrasonographic prediction of sentinel lymph node metastasis by real-time virtual sonography constructed with three-dimensional computed tomography-lymphography in breast cancer patients.
Breast cancer (Tokyo, Japan) 2012;19(1):77-82.
2011: Yufeng Wang; Shigefumi Yoshino; Xiulian Zhang; Norio Iizuka; Yasuhiro Kuramitsu; Masaaki Oka; Nobuaki Suzuki; Tomio Ueno; Kazuyuki Nakamura
Differential expression of up-regulated cofilin-1 and down-regulated cofilin-2 characteristic of pancreatic cancer tissues.
Oncology reports 2011;26(6):1595-9.
2011: Yufeng Wang; Yuichiro Yokoyama; Norio Iizuka; Yasuhiro Kuramitsu; Masaaki Oka; Isao Sakaida; Motonari Takashima; Takao Tamesa; Kazuyuki Nakamura
Identification of four isoforms of aldolase B down-regulated in hepatocellular carcinoma tissues by means of two-dimensional Western blotting.
In vivo (Athens, Greece) 2011;25(6):881-6.
2011: Yasuhiro Kuramitsu; Junko K Akada; Norio Iizuka; Masaaki Oka; Kiwamu Okita; Isao Sakaida; Motonari Takashima; Takao Tamesa; Toshifusa Toda; Yufeng Wang; Yuichiro Yokoyama; Kazuyuki Nakamura
Up-regulation of 42 kDa tubulin alpha-6 chain fragment in well-differentiated hepatocellular carcinoma tissues from patients infected with hepatitis C virus.
Anticancer research 2011;31(10):3331-6.
2011: Yufeng Wang; Yasuhiro Kuramitsu; Shigefumi Yoshino; Motonari Takashima; Xiulian Zhang; Tomio Ueno; Nobuaki Suzuki; Masaaki Oka; Kazuyuki Nakamura
Screening for serological biomarkers of pancreatic cancer by two-dimensional electrophoresis and liquid chromatography-tandem mass spectrometry.
Oncology reports 2011;26(1):287-92.
2011: Norio Iizuka; Masaaki Oka; Isao Sakaida; Toyoki Moribe; Toshiaki Miura; Naoki Kimura; Shigeru Tamatsukuri; Hideo Ishitsuka; Koichi Uchida; Shuji Terai; Satoyoshi Yamashita; Kiwamu Okita; Koichiro Sakata; Yoshiyasu Karino; Joji Toyota; Eiji Ando; Tatsuya Ide; Michio Sata; Ryouichi Tsunedomi; Masahito Tsutsui; Michihisa Iida; Yoshihiro Tokuhisa; Kazuhiko Sakamoto; Takao Tamesa; Yusuke Fujita; Yoshihiko Hamamoto
Efficient detection of hepatocellular carcinoma by a hybrid blood test of epigenetic and classical protein markers.
Clinica chimica acta; international journal of clinical chemistry 2011;412(1-2):152-8.
2010: Shigefumi Yoshino; Shin Yoshida; Noriko Maeda; Yoshinari Maeda; Kazunari Maeda; Shoichi Hazama; Masaaki Oka
[Clinical evaluation of the combination treatment of intrapleural or intraperitoneal administration of lentinan and OK-432 for malignant effusion].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(12):2798-800.
2010: Yoshitaro Shindo; Shigefumi Yoshino; Yoshinari Maeda; Nobuaki Suzuki; Masaaki Oka
[A case of unresectable advanced gastric cancer successfully treated with chemotherapy after gastrojejunostomy].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(12):2487-9.
2010: Shigefumi Yoshino; Kiyoshi Yoshimura; Nobuaki Suzuki; Michihisa Iida; Shin Yoshida; Yoshinari Maeda; Kazunari Maeda; Shoichi Hazama; Masaaki Oka
[Immunoregulatory effects of PSK on the Th1/Th2 balance and regulatory T-cells in patients with colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(12):2234-6.
2010: Yasuhiro Kuramitsu; Byron Baron; Shigefumi Yoshino; Xiulian Zhang; T Tanaka; Masakazu Yashiro; Kosei Hirakawa; Masaaki Oka; Kazuyuki Nakamura
Proteomic differential display analysis shows up-regulation of 14-3-3 sigma protein in human scirrhous-type gastric carcinoma cells.
Anticancer research 2010;30(11):4459-65.
2010: Shigeto Kawauchi; Tomoko Furuya; Kenzo Ikemoto; Motonao Nakao; Shigeru Yamamoto; Masaaki Oka; Kohsuke Sasaki
DNA copy number aberrations associated with aneuploidy and chromosomal instability in breast cancers.
Oncology reports 2010;24(4):875-83.
2010: Kiyoshi Yoshimura; Masaaki Oka; Kenzaburo Tani
[Genetic diagnosis of intestinal cancer].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 8():451-7.
2010: Kiyoshi Yoshimura; Kelly Olino; BARISH EDIL; Richard D Schulick; Masaaki Oka
Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer).
Surgery today 2010;40(5):404-10.
2010: Toshiyuki Okada; Yutaka Suehiro; Koji Ueno; Shoko Mitomori; Sayaka Kaneko; Mitsuaki Nishioka; Naoko Okayama; Kouhei Sakai; Shingo Higaki; Shoichi Hazama; Hiroshi Hirata; Isao Sakaida; Masaaki Oka; Yuji Hinoda
TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer.
Genes, chromosomes & cancer 2010;49(5):452-62.
2010: Taku Nishimura; Tomio Ueno; Hiroki Nakatsu; Atsunori Oga; Sei Kobayashi; Masaaki Oka
In vivo motility evaluation of the grafted gastric wall with small intestinal submucosa.
Tissue engineering. Part A 2010;16(5):1761-8.
2010: Masahito Tsutsui; Norio Iizuka; Toyoki Moribe; Toshiaki Miura; Naoki Kimura; Shigeru Tamatsukuri; Hideo Ishitsuka; Yusuke Fujita; Yoshihiko Hamamoto; Ryouichi Tsunedomi; Michihisa Iida; Yoshihiro Tokuhisa; Kazuhiko Sakamoto; Takao Tamesa; Isao Sakaida; Masaaki Oka
Methylated cyclin D2 gene circulating in the blood as a prognosis predictor of hepatocellular carcinoma.
Clinica chimica acta; international journal of clinical chemistry 2010;411(7-8):516-20.
2010: Shoichi Hazama; Atsushi Nagashima; Hiroshi Kondo; Shin Yoshida; Ryoichi Shimizu; Atsuhiro Araki; Shigefumi Yoshino; Naoko Okayama; Yuji Hinoda; Masaaki Oka
Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A1*28 polymorphism.
Cancer science 2010;101(3):722-7.
2010: Shigefumi Yoshino; Seiji Watanabe; Motohiro Imano; Tetsuya Suga; Saburo Nakazawa; Shoichi Hazama; Masaaki Oka
Improvement of QOL and prognosis by treatment of superfine dispersed lentinan in patients with advanced gastric cancer.
Hepato-gastroenterology 2010;57(97):172-7.
2010: Katumi Tsuji; Shigeto Kawauchi; Soichiro Saito; Tomoko Furuya; Kenzo Ikemoto; Motonao Nakao; Shigeru Yamamoto; Masaaki Oka; Takashi Hirano; Kohsuke Sasaki
Breast cancer cell lines carry cell line-specific genomic alterations that are distinct from aberrations in breast cancer tissues: comparison of the CGH profiles between cancer cell lines and primary cancer tissues.
BMC cancer 2010;10():15.
2010: Ryouichi Tsunedomi; Yasushi Ogawa; Norio Iizuka; Kazuhiko Sakamoto; Takao Tamesa; Toyoki Moribe; Masaaki Oka
The assessment of methylated BASP1 and SRD5A2 levels in the detection of early hepatocellular carcinoma.
International journal of oncology 2010;36(1):205-12.
2010: Shigeru Yamamoto; Noriko Maeda; Michiko Tamesa; Yukiko Nagashima; Kazuyoshi Suga; Masaaki Oka
Sentinel lymph node detection in breast cancer patients by real-time virtual sonography constructed with three-dimensional computed tomography-lymphography.
The breast journal 2010;16(1):4-8.
2009: Yusaku Watanabe; Masahito Tsutsui; Shigeru Takeda; Shigefumi Yoshino; Masaaki Oka
[A case of esophageal cancer associated with colon cancer successfully treated with combination chemotherapy of FOLFOX and concurrent radiotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):2439-41.
2009: Nobuaki Suzuki; Shigefumi Yoshino; Hideaki Somura; Tomio Ueno; Masaaki Oka
[A case of rapid growth GIST successfully treated with resection after long-term use of imatinib].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):2354-6.
2009: Masahito Tsutsui; Shigefumi Yoshino; Kazuhiko Sakamoto; Masaaki Oka
[Long-term survival after surgery and adjuvant imatinib in a patient with rectal GIST, local recurrence, liver metastases and mediastinal pleural metastasis].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):2351-3.
2009: Hiroki Nakatsu; Shoichi Hazama; Shinobu Tomochika; Kazuhiko Sakamoto; Shigefumi Yoshino; Masaaki Oka
[Extended lymphadenectomy for gastric regional lymph node metastasis from transverse colon cancer--a case report].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):2217-9.
2009: Shinobu Tomochika; Shouichi Hazama; Hiroki Nakatsu; Shin Yoshida; Yoshihiro Tokuhisa; Shigefumi Yoshino; Masaaki Oka
[A case of ascending colon cancer successfully treated for synchronous liver metastases with mFOLFOX6 after a resection of the primary tumor].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):2184-6.
2009: Kiyoshi Yoshimura; Kristen F Meckel; Lindsay S Laird; Christina Y Chia; Jang-June Park; Kelly L Olino; Ryouichi Tsunedomi; Toshio Harada; Norio Iizuka; Shoichi Hazama; Yukihiko Kato; Jesse W Keller; John M Thompson; Fumin Chang; Lewis H Romer; Ajay Jain; Christine A Iacobuzio-Donahue; Masaaki Oka; Drew M Pardoll; Richard D Schulick
Integrin alpha2 mediates selective metastasis to the liver.
Cancer research 2009;69(18):7320-8.
2009: Toyoki Moribe; Norio Iizuka; Toshiaki Miura; Naoki Kimura; Shigeru Tamatsukuri; Hideo Ishitsuka; Yoshihiko Hamamoto; Kazuhiko Sakamoto; Takao Tamesa; Masaaki Oka
Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2009;125(2):388-97.
2009: Takao Tamesa; Norio Iizuka; Naohide Mori; Toshimasa Okada; Norikazu Takemoto; Akira Tangoku; Masaaki Oka
High serum levels of vascular endothelial growth factor after hepatectomy are associated with poor prognosis in hepatocellular carcinoma.
Hepato-gastroenterology 2009;56(93):1122-6.
2009: Shoichi Hazama; Seiji Watanabe; Manabu Ohashi; Masashi Yagi; Michinari Suzuki; Kenji Matsuda; Tatsuhito Yamamoto; Yasuyo Suga; Tetsuya Suga; Saburo Nakazawa; Masaaki Oka
Efficacy of orally administered superfine dispersed lentinan (beta-1,3-glucan) for the treatment of advanced colorectal cancer.
Anticancer research 2009;29(7):2611-7.
2009: Naoki Kimura; Toyoki Moribe; Norio Iizuka; Toshiaki Miura; Shigeru Tamatsukuri; Hideo Ishitsuka; Yoshihiko Hamamoto; Masaaki Oka
Rapid and quantitative detection of CpG-methylation status using TaqMan PCR combined with methyl-binding-domain polypeptide.
Clinical biochemistry 2009;42(10-11):1113-22.
2009: Michiko Sato Tamesa; Yasuhiro Kuramitsu; Masanori Fujimoto; Noriko Maeda; Yukiko Nagashima; T Tanaka; Shigeru Yamamoto; Masaaki Oka; Kazuyuki Nakamura
Detection of autoantibodies against cyclophilin A and triosephosphate isomerase in sera from breast cancer patients by proteomic analysis.
Electrophoresis 2009;30(12):2168-81.
2009: Kazuhisa Tokuno; Shoichi Hazama; Shigefumi Yoshino; Shin Yoshida; Masaaki Oka
Increased prevalence of regulatory T-cells in the peripheral blood of patients with gastrointestinal cancer.
Anticancer research 2009;29(5):1527-32.
2009: Yasuyo Chochi; Shigeto Kawauchi; Motonao Nakao; Tomoko Furuya; Kiichiro Hashimoto; Atsunori Oga; Masaaki Oka; Kohsuke Sasaki
A copy number gain of the 6p arm is linked with advanced hepatocellular carcinoma: an array-based comparative genomic hybridization study.
The Journal of pathology 2009;217(5):677-84.
2009: Shin Yoshida; Shoichi Hazama; Kazuhisa Tokuno; Kazuhiko Sakamoto; Motonari Takashima; Takao Tamesa; Toshihiko Torigoe; Noriyuki Sato; Masaaki Oka
Concomitant overexpression of heat-shock protein 70 and HLA class-I in hepatitis C virus-related hepatocellular carcinoma.
Anticancer research 2009;29(2):539-44.
2009: Tomio Ueno; Motonari Takashima; Michihisa Iida; Shin Yoshida; Nobuaki Suzuki; Masaaki Oka
Improvement of early delayed gastric emptying in patients with Billroth I type of reconstruction after pylorus preserving pancreatoduodenectomy.
Journal of hepato-biliary-pancreatic surgery 2009;16(3):300-4.
2008: Toyoki Moribe; Norio Iizuka; Toshiaki Miura; Markus Stark; Shigeru Tamatsukuri; Hideo Ishitsuka; Yoshihiko Hamamoto; Kazuhiko Sakamoto; Takao Tamesa; Masaaki Oka
Identification of novel aberrant methylation of BASP1 and SRD5A2 for early diagnosis of hepatocellular carcinoma by genome-wide search.
International journal of oncology 2008;33(5):949-58.
2008: Michihisa Iida; Norio Iizuka; Isao Sakaida; Toyoki Moribe; Nozomi Fujita; Toshiaki Miura; Shigeru Tamatsukuri; Hideo Ishitsuka; Koichi Uchida; Shuji Terai; Yoshihiro Tokuhisa; Kazuhiko Sakamoto; Takao Tamesa; Takanobu Miyamoto; Yoshihiko Hamamoto; Masaaki Oka
Relation between serum levels of cell-free DNA and inflammation status in hepatitis C virus-related hepatocellular carcinoma.
Oncology reports 2008;20(4):761-5.
2008: Takashi Hamaguchi; Norio Iizuka; Ryouichi Tsunedomi; Yoshihiko Hamamoto; Takanobu Miyamoto; Michihisa Iida; Yoshihiro Tokuhisa; Kazuhiko Sakamoto; Motonari Takashima; Takao Tamesa; Masaaki Oka
Glycolysis module activated by hypoxia-inducible factor 1alpha is related to the aggressive phenotype of hepatocellular carcinoma.
International journal of oncology 2008;33(4):725-31.
2008: Toru Kawaoka; Masaaki Oka; Motonari Takashima; Tomio Ueno; Koutaro Yamamoto; Noboru Yahara; Shigefumi Yoshino; Shoichi Hazama
Adoptive immunotherapy for pancreatic cancer: cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1.
Oncology reports 2008;20(1):155-63.
2008: Toshiyuki Tanaka; Yasuhiro Kuramitsu; Masanori Fujimoto; Seiji Naito; Masaaki Oka; Kazuyuki Nakamura
Downregulation of two isoforms of ubiquitin carboxyl-terminal hydrolase isozyme L1 correlates with high metastatic potentials of human SN12C renal cell carcinoma cell clones.
Electrophoresis 2008;29(12):2651-9.
2008: Norio Iizuka; Yoshihiko Hamamoto; Ryouichi Tsunedomi; Masaaki Oka
Translational microarray systems for outcome prediction of hepatocellular carcinoma.
Cancer science 2008;99(4):659-65.
2008: Yuichiro Yokoyama; Yasuhiro Kuramitsu; Motonari Takashima; Masanori Fujimoto; Norio Iizuka; Shuji Terai; Kiwamu Okita; Isao Sakaida; Masaaki Oka; Deborah A Raynes; Vince Guerriero; Kazuyuki Nakamura
Increased expression of heat shock protein-binding protein 1 and heat shock protein 70 in human hepatocellular carcinoma tissues.
Molecular medicine reports 2008;1(2):197-201.
2008: Michiko Tamesa; Shigeru Yamamoto; Noriko Maeda; Yukiko Nagashima; Masaaki Oka
[Significance of pyrimidine nucleoside phosphorylase and dihydropyrimidine dehydrogenase levels to predict postoperative recurrence in primary breast cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2008;35(3):431-6.
2008: Ryouichi Tsunedomi; Norio Iizuka; Takao Tamesa; Kazuhiko Sakamoto; Takashi Hamaguchi; Hideaki Somura; Mamoru Yamada; Masaaki Oka
Decreased ID2 promotes metastatic potentials of hepatocellular carcinoma by altering secretion of vascular endothelial growth factor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1025-31.
2008: Shoichi Hazama; Masaaki Oka
[CPT-11 (Irinotecan)].
Gan to kagaku ryoho. Cancer & chemotherapy 2008;35(2):182-4.
2008: Hideaki Somura; Norio Iizuka; Takao Tamesa; Kazuhiko Sakamoto; Takashi Hamaguchi; Ryouichi Tsunedomi; Hisafumi Yamada-Okabe; Mikiko Sawamura; Masaya Eramoto; Takanobu Miyamoto; Yoshihiko Hamamoto; Masaaki Oka
A three-gene predictor for early intrahepatic recurrence of hepatocellular carcinoma after curative hepatectomy.
Oncology reports 2008;19(2):489-95.
2008: Hiroshi Kondo; Shoichi Hazama; Toru Kawaoka; Shigefumi Yoshino; Shin Yoshida; Kazuhisa Tokuno; Motonari Takashima; Tomio Ueno; Yuji Hinoda; Masaaki Oka
Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes.
Anticancer research 2008;28(1B):379-87.
2008: Kazuo Hashimoto; Yoshihisa Shimizu; Yutaka Suehiro; Naoko Okayama; Shinichi Hashimoto; Toshiyuki Okada; Mikako Hiura; Koji Ueno; Shoichi Hazama; Shingo Higaki; Yuichiro Hamanaka; Masaaki Oka; Isao Sakaida; Yuji Hinoda
Hypermethylation status of APC inversely correlates with the presence of submucosal invasion in laterally spreading colorectal tumors.
Molecular carcinogenesis 2008;47(1):1-8.
2007: Y Tokuhisa; Norio Iizuka; Isao Sakaida; T Moribe; N Fujita; Toshiaki Miura; Shigeru Tamatsukuri; Hideo Ishitsuka; Koichi Uchida; Shuji Terai; Kazuhiko Sakamoto; Takao Tamesa; Masaaki Oka
Circulating cell-free DNA as a predictive marker for distant metastasis of hepatitis C virus-related hepatocellular carcinoma.
British journal of cancer 2007;97(10):1399-403.
2007: Shigeru Takeda; Kazuhisa Tokuno; Taku Nishimura; Shigefumi Yoshino; Masaaki Oka
[A clinical study of esophagectomy after chemo-radiation therapy for advanced esophageal carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 2007;34(12):1982-4.
2007: Shunji Uchimura; Norio Iizuka; Takao Tamesa; Takanobu Miyamoto; Yoshihiko Hamamoto; Masaaki Oka
Resampling based on geographic patterns of hepatitis virus infection reveals a common gene signature for early intrahepatic recurrence of hepatocellular carcinoma.
Anticancer research 2007;27(5A):3323-30.
2007: Kuniko Mikuriya; Yasuhiro Kuramitsu; Shomei Ryozawa; Masanori Fujimoto; Sayaka Mori; Masaaki Oka; Kimikazu Hamano; Kiwamu Okita; Isao Sakaida; Kazuyuki Nakamura
Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/mass spectrometry.
International journal of oncology 2007;30(4):849-55.
2007: Shigeki Kanamura; Masaaki Oka
Post-prandial portal hemodynamics after upper gastrointestinal tract abscission.
Hepato-gastroenterology 2007;54(74):445-8.
2007: Toshio Harada; Yasuhiro Kuramitsu; Akira Makino; Masanori Fujimoto; Norio Iizuka; Yoshinobu Hoshii; Motonari Takashima; Michiko Tamesa; Taku Nishimura; Shigeru Takeda; Toshihiro Abe; Shigefumi Yoshino; Masaaki Oka; Kazuyuki Nakamura
Expression of tropomyosin alpha 4 chain is increased in esophageal squamous cell carcinoma as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/mass spectrometry.
Proteomics. Clinical applications 2007;1(2):215-23.
2006: Hiroaki Toshimitsu; Norio Iizuka; Kohtaro Yamamoto; Shigeto Kawauchi; Atsunori Oga; Tomoko Furuya; Masaaki Oka; Kohsuke Sasaki
Molecular features linked to the growth-inhibitory effects of gemcitabine on human pancreatic cancer cells.
Oncology reports 2006;16(6):1285-91.
2006: Ryouichi Tsunedomi; Norio Iizuka; Hisafumi Yamada-Okabe; Takao Tamesa; Toshimasa Okada; Kazuhiko Sakamoto; Motonari Takashima; Takeshi Hamaguchi; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto; Mamoru Yamada; Masaaki Oka
Identification of ID2 associated with invasion of hepatitis C virus-related hepatocellular carcinoma by gene expression profile.
International journal of oncology 2006;29(6):1445-51.
2006: Norio Iizuka; Isao Sakaida; Toyoki Moribe; Nozomi Fujita; Toshiaki Miura; Markus Stark; Shigeru Tamatsukuri; Hideo Ishitsuka; Koichi Uchida; Shuji Terai; Kazuhiko Sakamoto; Takao Tamesa; Masaaki Oka
Elevated levels of circulating cell-free DNA in the blood of patients with hepatitis C virus-associated hepatocellular carcinoma.
Anticancer research 2006;26(6C):4713-9.
2006: Shin Yoshida; Shoichi Hazama; Hiroshi Kondo; Kazuhiko Sakamoto; Takao Tamesa; Tomio Ueno; Masaaki Oka
[Adjuvant hepatic arterial infusion after resection of hepatic metastasis from colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2006;33(12):1845-7.
2006: Norio Iizuka; Takao Tamesa; Kazuhiko Sakamoto; Takanobu Miyamoto; Yoshihiko Hamamoto; Masaaki Oka
Different molecular pathways determining extrahepatic and intrahepatic recurrences of hepatocellular carcinoma.
Oncology reports 2006;16(5):1137-42.
2006: Kazuhiko Sakamoto; Masaaki Oka; Shigehumi Yoshino; Shoichi Hazama; Toshihiro Abe; Naoko Okayama; Yuji Hinoda
Relation between cytokine promoter gene polymorphism and toxicity of 5-fluorouracil plus cisplatin chemotherapy.
Oncology reports 2006;16(2):381-7.
2006: Motonari Takashima; Yasuhiro Kuramitsu; Yuichiro Yokoyama; Norio Iizuka; Toshio Harada; Masanori Fujimoto; Isao Sakaida; Kiwamu Okita; Masaaki Oka; Kazuyuki Nakamura
Proteomic analysis of autoantibodies in patients with hepatocellular carcinoma.
Proteomics 2006;6(13):3894-900.
2006: Norio Iizuka; Ryouichi Tsunedomi; Takao Tamesa; Toshimasa Okada; Kazuhiko Sakamoto; Takashi Hamaguchi; Hisafumi Yamada-Okabe; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto; Masaaki Oka
Involvement of c-myc-regulated genes in hepatocellular carcinoma related to genotype-C hepatitis B virus.
Journal of cancer research and clinical oncology 2006;132(7):473-81.
2006: Tomomitu Sato; Norio Iizuka; Yoshihiko Hamamoto; Shigefumi Yoshino; Toshihiro Abe; Shigeru Takeda; Shunji Uchimura; Takanobu Miyamoto; Fumiyoshi Sei; Kenji Hamada; Hisafumi Yamada-Okabe; Masaaki Oka
Esophageal squamous cell carcinomas with distinct invasive depth show different gene expression profiles associated with lymph node metastasis.
International journal of oncology 2006;28(5):1043-55.
2006: Yasuhiro Kuramitsu; Toshio Harada; Motonari Takashima; Yuuichirou Yokoyama; Isao Hidaka; Norio Iizuka; Tosifusa Toda; Masanori Fujimoto; Xiulian Zhang; Isao Sakaida; Kiwamu Okita; Masaaki Oka; Kazuyuki Nakamura
Increased expression and phosphorylation of liver glutamine synthetase in well-differentiated hepatocellular carcinoma tissues from patients infected with hepatitis C virus.
Electrophoresis 2006;27(8):1651-8.
2006: Yuichiro Yokoyama; Yasuhiro Kuramitsu; Motonari Takashima; Norio Iizuka; Shuji Terai; Masaaki Oka; Kazuyuki Nakamura; Kiwamu Okita; Isao Sakaida
Protein level of apolipoprotein E increased in human hepatocellular carcinoma.
International journal of oncology 2006;28(3):625-31.
2006: Hideto Hayashi; Akira Tangoku; Kazuyoshi Suga; Kensaku Shimizu; Katsuhiko Ueda; Shigefumi Yoshino; Toshihiro Abe; Tomomitsu Sato; Naofumi Matsunaga; Masaaki Oka
CT lymphography-navigated sentinel lymph node biopsy in patients with superficial esophageal cancer.
Surgery 2006;139(2):224-35.
2006: Toru Kawaoka; Motonari Takashima; Koutaro Yamamoto; Tomio Ueno; Masaaki Oka
[Adoptive immunotherapy using MUC1--specific CTLs for unresectable pancreatic cancer].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 1():279-82.
2005: Kazuyoshi Suga; Kensaku Shimizu; Yasuhiko Kawakami; Akira Tangoku; Mohammed Zaki; Naofumi Matsunaga; Masaaki Oka
Lymphatic drainage from esophagogastric tract: feasibility of endoscopic CT lymphography for direct visualization of pathways.
Radiology 2005;237(3):952-60.
2005: Shigefumi Yoshino; Shoichi Hazama; Ryouichi Shimizu; Shintaroh Fukuda; Akitoshi Kudoh; Eishi Mizuta; Yutaka Ogura; Akiko Sano; Masaaki Oka
[Usefulness in predicting parameters for the selection of responders who received immunochemotherapy with PSK in patients with colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2005;32(11):1568-70.
2005: Toru Kawaoka; Shigefumi Yoshino; Hiroshi Kondo; Koutaro Yamamoto; Shoichi Hazama; Masaaki Oka
[Clinical evaluation of intrapleural or peritoneal repetitive administration of Lentinan and OK-432 for malignant effusion].
Gan to kagaku ryoho. Cancer & chemotherapy 2005;32(11):1565-7.
2005: Yukiko Nagashima; Noriko Sanpei; Shigeru Yamamoto; Shigehumi Yoshino; Akira Tangoku; Masaaki Oka
[Evaluation of host immunity and side effects in breast cancer patients treated with adjuvant chemotherapy (FEC therapy)].
Gan to kagaku ryoho. Cancer & chemotherapy 2005;32(11):1550-2.
2005: Kotaro Yamamoto; Tomio Ueno; Toru Kawaoka; Shoichi Hazama; Mikiko Fukui; Yutaka Suehiro; Yuichiro Hamanaka; Yoshito Ikematsu; Kohzoh Imai; Masaaki Oka; Yuji Hinoda
MUC1 peptide vaccination in patients with advanced pancreas or biliary tract cancer.
Anticancer research 2005;25(5):3575-9.
2005: Ryouichi Tsunedomi; Norio Iizuka; Yoshihiko Hamamoto; Shunji Uchimura; Takanobu Miyamoto; Takao Tamesa; Toshimasa Okada; Norikazu Takemoto; Motonari Takashima; Kazuhiko Sakamoto; Kenji Hamada; Hisafumi Yamada-Okabe; Masaaki Oka
Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma.
International journal of oncology 2005;27(3):661-7.
2005: Akiko Hara; Norio Iizuka; Yoshihiko Hamamoto; Shunji Uchimura; Takanobu Miyamoto; Ryouichi Tsunedomi; Koji Miyamoto; Shoichi Hazama; Kiwamu Okita; Masaaki Oka
Molecular dissection of a medicinal herb with anti-tumor activity by oligonucleotide microarray.
Life sciences 2005;77(9):991-1002.
2005: Katsuhiro Matoba; Norio Iizuka; Toshikazu Gondo; Tokuhiro Ishihara; Hisafumi Yamada-Okabe; Takao Tamesa; Norikazu Takemoto; Kiichiro Hashimoto; Kazuhiko Sakamoto; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto; Masaaki Oka
Tumor HLA-DR expression linked to early intrahepatic recurrence of hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2005;115(2):231-40.
2005: Kazuyoshi Suga; Shigeru Yamamoto; Akira Tangoku; Masaaki Oka; Yasuhiko Kawakami; Naofumi Matsunaga
Breast sentinel lymph node navigation with three-dimensional interstitial multidetector-row computed tomographic lymphography.
Investigative radiology 2005;40(6):336-42.
2005: Koutaro Yamamoto; Takashi Mine; Kazuko Katagiri; Nobuaki Suzuki; Toru Kawaoka; Tomio Ueno; Satoko Matsueda; Akira Yamada; Kyogo Itoh; Hideaki Yamana; Masaaki Oka
Immunological evaluation of personalized peptide vaccination for patients with pancreatic cancer.
Oncology reports 2005;13(5):874-83.
2005: Motonari Takashima; Yasuhiro Kuramitsu; Yuichiro Yokoyama; Norio Iizuka; Masanori Fujimoto; Takashi Nishisaka; Kiwamu Okita; Masaaki Oka; Kazuyuki Nakamura
Overexpression of alpha enolase in hepatitis C virus-related hepatocellular carcinoma: association with tumor progression as determined by proteomic analysis.
Proteomics 2005;5(6):1686-92.
2005: Norikazu Takemoto; Norio Iizuka; Hisafumi Yamada-Okabe; Kenji Hamada; Takao Tamesa; Toshimasa Okada; Kiichiro Hashimoto; Kazuhiko Sakamoto; Motonari Takashima; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto; Masaaki Oka
Sex-based molecular profiling of hepatitis C virus-related hepatocellular carcinoma.
International journal of oncology 2005;26(3):673-8.
2005: Norio Iizuka; Masaaki Oka; Hisafumi Yamada-Okabe; Naohide Mori; Takao Tamesa; Toshimasa Okada; Norikazu Takemoto; Kazuhiko Sakamoto; Kenji Hamada; Hideo Ishitsuka; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto
Self-organizing-map-based molecular signature representing the development of hepatocellular carcinoma.
FEBS letters 2005;579(5):1089-100.
2005: Tomio Ueno; Koutaro Yamamoto; Toru Kawaoka; Motonari Takashima; Masaaki Oka
Current antibiotic prophylaxis in pancreatoduodenectomy in Japan.
Journal of hepato-biliary-pancreatic surgery 2005;12(4):304-9.
2004: Norio Iizuka; Yoshihiko Hamamoto; Masaaki Oka
Predicting individual outcomes in hepatocellular carcinoma.
Lancet 2004;364(9448):1837-9.
2004: Norio Iizuka; Masaaki Oka; Takao Tamesa; Yoshihiko Hamamoto; Hisafumi Yamada-Okabe
Imbalance in expression levels of insulin-like growth factor 2 and H19 transcripts linked to progression of hepatocellular carcinoma.
Anticancer research 2004;24(6):4085-9.
2004: Yoshitaka Maeda; Minekatsu Nishida; Takashi Takao; Naohide Mori; Takao Tamesa; Akira Tangoku; Masaaki Oka
Risk factors for postoperative liver failure after hepatectomy for hepatocellular carcinoma.
Hepato-gastroenterology 2004;51(60):1792-6.
2004: Takao Tamesa; Yusaku Watanabe; Kiyoshi Yoshimura; Naohide Mori; Shigeru Yamamoto; Shoichi Hazama; Akira Tangoku; Masaaki Oka
[A case of disseminated tumor from cecal cancer with survival for over 5 years after twice surgical resection and systemic chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2004;31(11):1864-6.
2004: Atsuhiro Araki; Shoichi Hazama; Kiyoshi Yoshimura; Shigefumi Yoshino; Norio Iizuka; Masaaki Oka
Tumor secreting high levels of IL-15 induces specific immunity to low immunogenic colon adenocarcinoma via CD8+ T cells.
International journal of molecular medicine 2004;14(4):571-6.
2004: Hiroaki Toshimitsu; Kiichiro Hashimoto; Akira Tangoku; Norio Iizuka; Kohtaro Yamamoto; Shigeto Kawauchi; Atsunori Oga; Tomoko Furuya; Masaaki Oka; Kohsuke Sasaki
Molecular signature linked to acquired resistance to cisplatin in esophageal cancer cells.
Cancer letters 2004;211(1):69-78.
2004: Yuichiro Yokoyama; Yasuhiro Kuramitsu; Motonari Takashima; Norio Iizuka; Toshifusa Toda; Shuji Terai; Isao Sakaida; Masaaki Oka; Kazuyuki Nakamura; Kiwamu Okita
Proteomic profiling of proteins decreased in hepatocellular carcinoma from patients infected with hepatitis C virus.
Proteomics 2004;4(7):2111-6.
2004: Akira Tangoku; Shigeru Yamamoto; Kazuyoshi Suga; Katsuhiko Ueda; Yukiko Nagashima; Makoto Hida; Tomomitsu Sato; Kazuhiko Sakamoto; Masaaki Oka
Sentinel lymph node biopsy using computed tomography-lymphography in patients with breast cancer.
Surgery 2004;135(3):258-65.
2004: Norio Iizuka; Masaaki Oka; Hisafumi Yamada-Okabe; Kenji Hamada; Hironobu Nakayama; Naohide Mori; Takao Tamesa; Toshimasa Okada; Norikazu Takemoto; Katsuhiro Matoba; Motonari Takashima; Katsuhiko Sakamoto; Akira Tangoku; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto
Molecular signature in three types of hepatocellular carcinoma with different viral origin by oligonucleotide microarray.
International journal of oncology 2004;24(3):565-74.
2004: Akira Tangoku; S Yoshino; Toshihiro Abe; Hideto Hayashi; T Satou; Tomio Ueno; Masaaki Oka
Mediastinoscope-assisted transhiatal esophagectomy for esophageal cancer.
Surgical endoscopy 2004;18(3):383-9.
2004: Kazuyoshi Suga; Yue Yuan; Munemasa Okada; Naofumi Matsunaga; Akira Tangoku; Shigeru Yamamoto; Masaaki Oka
Breast sentinel lymph node mapping at CT lymphography with iopamidol: preliminary experience.
Radiology 2004;230(2):543-52.
2003: Toshimasa Okada; Norio Iizuka; Hisafumi Yamada-Okabe; Naohide Mori; Takao Tamesa; Norikazu Takemoto; Akira Tangoku; Kenji Hamada; Hironobu Nakayama; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto; Masaaki Oka
Gene expression profile linked to p53 status in hepatitis C virus-related hepatocellular carcinoma.
FEBS letters 2003;555(3):583-90.
2003: Motonari Takashima; Yasuhiro Kuramitsu; Yuuichiro Yokoyama; Norio Iizuka; Toshifusa Toda; Isao Sakaida; Kiwamu Okita; Masaaki Oka; Kazuyuki Nakamura
Proteomic profiling of heat shock protein 70 family members as biomarkers for hepatitis C virus-related hepatocellular carcinoma.
Proteomics 2003;3(12):2487-93.
2003: Norio Iizuka; Masaaki Oka; Kotaro Yamamoto; Akira Tangoku; Koji Miyamoto; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto; Kiwamu Okita
Identification of common or distinct genes related to antitumor activities of a medicinal herb and its major component by oligonucleotide microarray.
International journal of cancer. Journal international du cancer 2003;107(4):666-72.
2003: Takashi Ueno; Akira Tangoku; Shigefumi Yoshino; Toshihiro Abe; Hideto Hayashi; Hiroaki Toshimitsu; Kiichiro Hashimoto; Tomomitsu Satoh; Atsunori Oga; Tomoko Furuya; Masaaki Oka; Kohsuke Sasaki
Prediction of nodal metastasis by comparative genomic hybridization in biopsy specimens from patients with superficial esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(14):5137-41.
2003: Masatoshi Kato; Shoichi Hazama; Kazuhiko Sakamoto; Shigefumi Yoshino; Akira Tangoku; Masaaki Oka
[Significance of intracellular cytokines levels in peripheral lymphocytes for evaluation of surgical stress after hepatectomy in patients with hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(11):1848-50.
2003: Takao Tamesa; Naohide Mori; Toshimasa Okada; Norikazu Takemoto; Kazuhiko Sakamoto; Takahiro Yamasaki; Akira Tangoku; Masaaki Oka
[A case of Vp4 hepatocellular carcinoma treated with surgical resection and continuous intrahepatic artery infusion chemotherapy of low-dose cisplatin and 5-fluorouracil].
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(11):1769-72.
2003: Toru Kawaoka; Shigefumi Yoshino; Shoichi Hazama; Akira Tangoku; Masaaki Oka
[Clinical evaluation of intrapleural or peritoneal administration of lentinan and OK-432 for malignant effusion].
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(11):1562-5.
2003: Atsuhiro Araki; Shoichi Hazama; Masaaki Oka; Yuji Hinoda
[Polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 in colorectal cancer].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():229-32.
2003: Shoichi Hazama; Masaaki Oka; Yuji Hinoda
[Polymorphism in colorectal cancer].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():42-6.
2003: Toshihiro Abe; Akira Tangoku; Masaaki Oka
[Esophageal diverticula].
Nihon Geka Gakkai zasshi 2003;104(9):601-5.
2003: Norio Iizuka; Masaaki Oka; Hisafumi Yamada-Okabe; Naohide Mori; Takao Tamesa; Toshimasa Okada; Norikazu Takemoto; Kiichiro Hashimoto; Akira Tangoku; Kenji Hamada; Hironobu Nakayama; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto
Differential gene expression in distinct virologic types of hepatocellular carcinoma: association with liver cirrhosis.
Oncogene 2003;22(19):3007-14.
2003: Norio Iizuka; Masaaki Oka; Hisafumi Yamada-Okabe; Minekatsu Nishida; Yoshitaka Maeda; Naohide Mori; Takashi Takao; Takao Tamesa; Akira Tangoku; Hisahiro Tabuchi; Kenji Hamada; Hironobu Nakayama; Hideo Ishitsuka; Takanobu Miyamoto; Akira Hirabayashi; Shunji Uchimura; Yoshihiko Hamamoto
Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection.
Lancet 2003;361(9361):923-9.
2003: Yuji Hinoda; Yoshito Ikematsu; Michiko Horinochi; Shuji Sato; Kotaro Yamamoto; Tomoko Nakano; Mikiko Fukui; Yutaka Suehiro; Yuichiro Hamanaka; Yoshiro Nishikawa; Hideo Kida; Shinji Waki; Masaaki Oka; Kohzoh Imai; Suguru Yonezawa
Increased expression of MUC1 in advanced pancreatic cancer.
Journal of gastroenterology 2003;38(12):1162-6.
2003: Norio Iizuka; Naohide Mori; Takao Tamesa; Akira Tangoku; Masaaki Oka
Telomerase activity and Nm23-H2 protein expression in hepatocellular carcinoma.
Anticancer research 2003;23(1A):43-7.
2003: Koji Matsuoka; Tomio Ueno; Katsuhiko Morita; Hiroo Kawano; Kazuhito Yamaguchi; Tsuyoshi Maekawa; Akira Tangoku; Masaaki Oka
Effects of moderate hypothermia on proinflammatory cytokine production in a rat model of caerulein-induced pancreatitis.
Pancreas 2003;26(1):e12-7.
2002: Yuji Hinoda; Naoko Okayama; Naofumi Takano; Kozue Fujimura; Yutaka Suehiro; Yuichiro Hamanaka; Shoichi Hazama; Yutaka Kitamura; Naoyuki Kamatani; Masaaki Oka
Association of functional polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 genes with colorectal cancer.
International journal of cancer. Journal international du cancer 2002;102(5):526-9.
2002: Koutaro Yamamoto; Noboru Yahara; Toru Kawaoka; Hideto Hayashi; Shoichi Hazama; Akira Tangoku; Masaaki Oka
[An autopsy case of sepsis following radiofrequency ablation (RFA) for metastatic liver carcinoma after bile duct reconstruction].
Gan to kagaku ryoho. Cancer & chemotherapy 2002;29(12):2238-41.
2002: Kiyoshi Yoshimura; Shoichi Hazama; Norio Iizuka; Naofumi Takano; Kohji Matsuoka; Akira Tangoku; Masaaki Oka
[Hepatic arterial infusion of IL-2 and chemotherapy for unresectable liver metastasis from colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2002;29(12):2117-20.
2002: Noboru Yahara; Toshihiro Abe; K Morita; Akira Tangoku; Masaaki Oka
Comparison of interleukin-6, interleukin-8, and granulocyte colony-stimulating factor production by the peritoneum in laparoscopic and open surgery.
Surgical endoscopy 2002;16(11):1615-9.
2002: Mitsuo Nakamura; Masaaki Oka; Norio Iizuka; Shigeto Kawauchi; Toshikazu Gondo; Tomio Ueno; Akira Tangoku
Osteopontin expression in chronic pancreatitis.
Pancreas 2002;25(2):182-7.
2002: Norio Iizuka; Masaaki Oka; Hisafumi Yamada-Okabe; Naohide Mori; Takao Tamesa; Toshimasa Okada; Norikazu Takemoto; Akira Tangoku; Kenji Hamada; Hironobu Nakayama; Takanobu Miyamoto; Shunji Uchimura; Yoshihiko Hamamoto
Comparison of gene expression profiles between hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma by oligonucleotide microarray data on the basis of a supervised learning method.
Cancer research 2002;62(14):3939-44.
2002: Norio Iizuka; Shoichi Hazama; Kiyoshi Yoshimura; Shigefumi Yoshino; Akira Tangoku; Koji Miyamoto; Kiwamu Okita; Masaaki Oka
Anticachectic effects of the natural herb Coptidis rhizoma and berberine on mice bearing colon 26/clone 20 adenocarcinoma.
International journal of cancer. Journal international du cancer 2002;99(2):286-91.
2002: Noboru Yahara; Masaaki Oka
[Immunotherapy for unresectable pancreatic cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2002;29(3):390-7.
2002: Naofumi Takano; Norio Iizuka; Shoichi Hazama; Shigefumi Yoshino; Akira Tangoku; Masaaki Oka
Expression of estrogen receptor-alpha and -beta mRNAs in human gastric cancer.
Cancer letters 2002;176(2):129-35.
2002: Takashi Ueno; Akira Tangoku; Shigefumi Yoshino; Toshihiro Abe; Hiroaki Toshimitsu; Tomoko Furuya; Shigeto Kawauchi; Atsunori Oga; Masaaki Oka; Kohsuke Sasaki
Gain of 5p15 detected by comparative genomic hybridization as an independent marker of poor prognosis in patients with esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):526-33.
2002: Naoko Okayama; Kozue Fujimura; Yutaka Suehiro; Yuichiro Hamanaka; Motoki Fujiwara; Tomoyo Matsubara; Tsuyoshi Maekawa; Shoichi Hazama; Masaaki Oka; Hiroaki Nohara; Kozo Kayano; Kiwamu Okita; Yuji Hinoda
Simple genotype analysis of the Asp299Gly polymorphism of the Toll-like receptor-4 gene that is associated with lipopolysaccharide hyporesponsiveness.
Journal of clinical laboratory analysis 2002;16(1):56-8.
2001: Norio Iizuka; Akira Tangoku; Shoichi Hazama; Shigefumi Yoshino; Naohide Mori; Masaaki Oka
Nm23-H1 gene as a molecular switch between the free-floating and adherent states of gastric cancer cells.
Cancer letters 2001;174(1):65-71.
2001: Yoshitaka Maeda; Minekatsu Nishida; N Mori; Takao Tamesa; T Okada; Akira Tangoku; Masaaki Oka
[Combined hepatocellular carcinoma and cholangiocellular carcinoma].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 6():401-5.
2001: Naofumi Takano; K Saito; Akira Tangoku; Masaaki Oka
[Local therapy for stage IV advanced breast cancer with brain metastasis].
Gan to kagaku ryoho. Cancer & chemotherapy 2001;28(11):1783-6.
2001: Toshihiro Abe; Masaaki Oka; Akira Tangoku; Hideto Hayashi; Koutaro Yamamoto; Noboru Yahara; K Morita; T Tabata; Y Ohmoto
Interleukin-6 production in lung tissue after transthoracic esophagectomy.
Journal of the American College of Surgeons 2001;192(3):322-9.
2001: Kiyoshi Yoshimura; Shoichi Hazama; Norio Iizuka; Shigefumi Yoshino; K Yamamoto; M Muraguchi; Y Ohmoto; T Noma; Masaaki Oka
Successful immunogene therapy using colon cancer cells (colon 26) transfected with plasmid vector containing mature interleukin-18 cDNA and the Igkappa leader sequence.
Cancer gene therapy 2001;8(1):9-16.
2000: Shigefumi Yoshino; T Tabata; Shoichi Hazama; Norio Iizuka; Koutaro Yamamoto; M Hirayama; Akira Tangoku; Masaaki Oka
Immunoregulatory effects of the antitumor polysaccharide lentinan on Th1/Th2 balance in patients with digestive cancers.
Anticancer research 2000;20(6C):4707-11.
2000: N lizuka; K Miyamoto; Akira Tangoku; H Hayashi; Shoichi Hazama; Shigefumi Yoshino; Kiyoshi Yoshimura; K Hirose; H Yoshida; Masaaki Oka
Downregulation of intracellular nm23-H1 prevents cisplatin-induced DNA damage in oesophageal cancer cells: possible association with Na(+), K(+)-ATPase.
British journal of cancer 2000;83(9):1209-15.
2000: Yoshitaka Maeda; Minekatsu Nishida; T Takao; Naohide Mori; Takao Tamesa; Y Maeda; Akira Tangoku; Masaaki Oka; H Shirasawa
[Hepatocellular carcinoma with tumor thrombus in the portal and hepatic veins treated successfully with hepatectomy and chemotherapy--a case report].
Gan to kagaku ryoho. Cancer & chemotherapy 2000;27(12):1951-4.
2000: T Takao; M Nisida; Yoshitaka Maeda; Naohide Mori; Takao Tamesa; Akira Tangoku; Masaaki Oka
[Significance of reduction surgery for giant hepatocellular carcinoma with diffuse lung metastases and multiple intrahepatic metastases].
Gan to kagaku ryoho. Cancer & chemotherapy 2000;27(12):1947-50.
2000: Norio Iizuka; Koji Miyamoto; Shoichi Hazama; Shigefumi Yoshino; Kiyoshi Yoshimura; Kiwamu Okita; T Fukumoto; S Yamamoto; Akira Tangoku; Masaaki Oka
Anticachectic effects of Coptidis rhizoma, an anti-inflammatory herb, on esophageal cancer cells that produce interleukin 6.
Cancer letters 2000;158(1):35-41.
2000: T Ueda; T Sakabe; Masaaki Oka; Yoshitaka Maeda; Minekatsu Nishida; F Murakami; T Maekawa
Levels of interleukin (IL)-6, IL-8, and IL-1 receptor antagonist in the hepatic vein following liver surgery.
Hepato-gastroenterology 2000;47(34):1048-51.
2000: Akira Tangoku; Hideto Hayashi; S Kanamura; S Yoshino; Toshihiro Abe; Y Yoshimoto; T Morioka; Masaaki Oka
Lymph node metastases identified with mediastinoscopy in a patient with superficial carcinoma of the esophagus.
Surgical endoscopy 2000;14(6):595.
2000: Akira Tangoku; H Hayashi; S Yoshino; Toshihiro Abe; K Tada; K Morita; T Ueno; Masaaki Oka
[Esophageal dilation therapy for achalasia of the esophagus].
Nihon Geka Gakkai zasshi 2000;101(4):345-51.
2000: Norio Iizuka; Koji Miyamoto; Kiwamu Okita; Akira Tangoku; H Hayashi; S Yosino; T Abe; T Morioka; Shoichi Hazama; Masaaki Oka
Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines.
Cancer letters 2000;148(1):19-25.
1999: K Hirazawa; Shoichi Hazama; Masaaki Oka
Depressed cytotoxic activity of hepatic nonparenchymal cells in rats with obstructive jaundice.
Surgery 1999;126(5):900-7.
1999: Yoshitaka Maeda; Minekatsu Nishida; T Takao; K Harada; Naohide Mori; Takao Tamesa; H Somura; Akira Tangoku; Masaaki Oka; T Konishi
[A case of multiple liver metastases from breast cancer successfully treated with intra-arterial administration of docetaxel].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(12):1951-4.
1999: T Takao; M Nisida; Yoshitaka Maeda; Naohide Mori; Takao Tamesa; Akira Tangoku; Masaaki Oka
[Study of continuous arterial infusion chemotherapy with low-dose cisplatin and 5-fluorouracil for patients with hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(12):1836-40.
1999: Akira Tangoku; K Yamamoto; K Hirazawa; T Takao; N Mori; K Tada; Masaaki Oka
Laparoscopic resection of large leiomyomas of the gastric fundus.
Surgical endoscopy 1999;13(10):1050-2.
1999: Toshihiro Abe; Akira Tangoku; Hideto Hayashi; S Takeda; S Yoshino; Masaaki Oka
Esophageal perforation and mediastinal abscess following placement of a covered self-expanding metallic stent and radiation therapy in a cancer patient.
Surgical endoscopy 1999;13(10):1044-6.
1999: Norio Iizuka; K Hirose; T Noma; Shoichi Hazama; Akira Tangoku; H Hayashi; T Abe; K Yamamoto; Masaaki Oka
The nm23-H1 gene as a predictor of sensitivity to chemotherapeutic agents in oesophageal squamous cell carcinoma.
British journal of cancer 1999;81(3):469-75.
1999: Akira Tangoku; Hideto Hayashi; S Yoshino; T Ueno; Toshihiro Abe; Y Yoshimoto; T Morioka; Masaaki Oka
Wire-guided transoral esophagogastrostomy for carcinoma of the cervical esophagus.
Journal of the American College of Surgeons 1999;189(3):330-3.
1999: Norio Iizuka; Shoichi Hazama; K Hirose; T Abe; N Tokuda; T Fukumoto; Akira Tangoku; Masaaki Oka
Interleukin-1 receptor antagonist mRNA expression and the progression of gastric carcinoma.
Cancer letters 1999;142(2):179-84.
1999: T Ueno; Masaaki Oka; K Nishihara; Koutaro Yamamoto; M Nakamura; Noboru Yahara; T Adachi
Laparoscopic distal pancreatectomy with preservation of the spleen.
Surgical laparoscopy, endoscopy & percutaneous techniques 1999;9(4):290-3.
1999: A Inaba; T Uchiyama; Masaaki Oka
Role of prostaglandin E2 in rat colon carcinoma.
Hepato-gastroenterology 1999;46(28):2347-51.
1999: Masaaki Oka; S Hazama; M Takahashi; K Yamamoto; T Abe; S Yoshino; H Hayashi; Akira Tangoku
Relationship between serum levels of soluble interleukin-2 receptor and various disease parameters in patients with squamous cell carcinoma of the esophagus.
Hepato-gastroenterology 1999;46(28):2254-9.
1999: Y Masaki; Masaaki Oka; Y Ogura; Tomio Ueno; K Nishihara; Akira Tangoku; M Takahashi; M Yamamoto; T Irimura
Sialylated MUC1 mucin expression in normal pancreas, benign pancreatic lesions, and pancreatic ductal adenocarcinoma.
Hepato-gastroenterology 1999;46(28):2240-5.
1999: Shoichi Hazama; T Noma; F Wang; Norio Iizuka; Y Ogura; Kiyoshi Yoshimura; E Inoguchi; M Hakozaki; K Hirose; T Suzuki; Masaaki Oka
Tumour cells engineered to secrete interleukin-15 augment anti-tumour immune responses in vivo.
British journal of cancer 1999;80(9):1420-6.
1999: Masaaki Oka; Y Yoshimoto; T Ueno; Kiyoshi Yoshimura; Y Maeda; A Tangoku
Treatment of cholecystoduodenal fistula by laparoscopy.
Surgical laparoscopy, endoscopy & percutaneous techniques 1999;9(3):213-6.
1999: T Ueda; T Sakabe; Masaaki Oka; Yoshitaka Maeda; Minekatsu Nishida; F Murakami; T Maekawa
Decreased hepatic nitric oxide synthesis during liver surgery.
Hepato-gastroenterology 1999;46(27):1917-22.
1999: Norio Iizuka; Akira Tangoku; H Hayashi; S Yosino; T Abe; T Morioka; Masaaki Oka
The association between nm23-H1 expression and survival in patients with esophageal squamous cell carcinoma.
Cancer letters 1999;138(1-2):139-44.
1999: T Tabata; Shoichi Hazama; Shigefumi Yoshino; Masaaki Oka
Th2 subset dominance among peripheral blood T lymphocytes in patients with digestive cancers.
American journal of surgery 1999;177(3):203-8.
1999: T Takao; M Nishida; Y Maeda; S Hiraki; K Takao; A Tangoku; Masaaki Oka
Effect of cautery with irrigation forceps on the remnant liver after hepatectomy in rats.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1999;31(2):173-9.
1998: Minekatsu Nishida; Yoshitaka Maeda; K Takao; K Harada; R Etoh; Akira Tangoku; Masaaki Oka
[Combined hepatic resection and removal of portal vein tumor thrombi].
Gan to kagaku ryoho. Cancer & chemotherapy 1998;25(9):1374-7.
1997: Tomio Ueno; Masaaki Oka
[A case of far-advanced gastric cancer treated with continuous 5-fluorouracil injection and intrahepatic arterial infusion of low-dose cisplatin].
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24(12):1855-7.
1997: T Takao; Minekatsu Nishida; Yoshitaka Maeda; K Takao; Masaaki Oka
[The study of continuous infusion chemotherapy with low-dose cisplatin and 5-fluorouracil for patients with primary liver cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24(12):1724-7.
1997: K Hirazawa; Masaaki Oka; Y Ogura; M Miyahara; Shoichi Hazama; T Suzuki
New technique for inducing reversible obstructive jaundice in the rat.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1997;29(3):195-201.
1996: Masaaki Oka; Norio Iizuka; K Yamamoto; Toshikazu Gondo; T Abe; Shoichi Hazama; Y Akitomi; Y Koishihara; Y Ohsugi; Y Ooba; T Ishihara; T Suzuki
The influence of interleukin-6 on the growth of human esophageal cancer cell lines.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(12):1001-6.
1996: Y Masaki; Masaaki Oka
[Adoptive immunotherapy for pancreatic cancer, using MUC1 specific CTL].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(12):1679-80.
1996: S Hiraki; Minekatsu Nishida; Yoshitaka Maeda; K Nakashima; K Takao; T Takao; Masaaki Oka; T Suzuki
[Effects of intra-hepatic arterial injection of mitoxantrone for hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(11):1415-8.
1996: Masaaki Oka; K Yamamoto; M Takahashi; M Hakozaki; T Abe; Norio Iizuka; Shoichi Hazama; K Hirazawa; H Hayashi; Akira Tangoku; K Hirose; T Ishihara; T Suzuki
Relationship between serum levels of interleukin 6, various disease parameters and malnutrition in patients with esophageal squamous cell carcinoma.
Cancer research 1996;56(12):2776-80.
1996: K Wadamori; Masaaki Oka; Nobuko Tokuda; Yoshihisa Fujikura; Shoichi Hazama; Tetsuo Fukumoto; T Suzuki
Influence of continuous interleukin-2 administration via the portal vein on liver regeneration following partial hepatectomy in rats.
Hepatology (Baltimore, Md.) 1996;23(6):1578-83.
1996: S Hiraki; Minekatsu Nishida; K Takao; Masaaki Oka; T Suzuki
Effects of hepatic denervation on ischemia-reperfusion injury in dogs.
Transplantation proceedings 1996;28(3):1275-8.
1996: Masaaki Oka; K Hirazawa; K Yamamoto; Norio Iizuka; Shoichi Hazama; T Suzuki; N Kobayashi
Induction of Fas-mediated apoptosis on circulating lymphocytes by surgical stress.
Annals of surgery 1996;223(4):434-40.
1996: Masaaki Oka; K Hiwaki; K Takao; N Iizuka; K Yamamoto; T Suzuki
The saline ballooning method for peritoneal dissection during laparoscopic herniorrhaphy.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(4):448-9.
1996: Masaaki Oka; Shoichi Hazama; M Suzuki; F Wang; K Wadamori; Norio Iizuka; S Takeda; Y Akitomi; Y Ohba; K Kajiwara; T Suga; T Suzuki
In vitro and in vivo analysis of human leukocyte binding by the antitumor polysaccharide, lentinan.
International journal of immunopharmacology 1996;18(3):211-6.
1995: Masaaki Oka; K Hirose; Norio Iizuka; K Aoyagi; K Yamamoto; T Abe; Shoichi Hazama; T Suzuki
Cytokine mRNA expression patterns in human esophageal cancer cell lines.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(11):1005-9.
1995: Masaaki Oka; Shoichi Hazama; M Suzuki; Y Ogura; N Kobayashi; T Suzuki
Histological analysis of hepatocellular carcinoma treated by intraarterial combined immunochemotherapy.
Hepato-gastroenterology 1995;42(5):561-6.
1995: K Wadamori; Masaaki Oka; R Shimizu; Akira Tangoku; Shoichi Hazama; T Yagyu; T Suzuki; S Hatano; Fumie Kurokawa; Kiwamu Okita
[A case of multiple liver metastasis from ileac carcinoid effectively treated with continuous intraarterial infusion of somatostatin analog].
Gan to kagaku ryoho. Cancer & chemotherapy 1995;22(11):1669-72.
1995: Shoichi Hazama; Masaaki Oka; S Yoshino; Norio Iizuka; K Wadamori; K Yamamoto; K Hirazawa; F Wang; Y Ogura; Y Masaki
[Clinical effects and immunological analysis of intraabdominal and intrapleural injection of lentinan for malignant ascites and pleural effusion of gastric carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 1995;22(11):1595-7.
1995: Norio Iizuka; Masaaki Oka; T Noma; A Nakazawa; K Hirose; T Suzuki
NM23-H1 and NM23-H2 messenger RNA abundance in human hepatocellular carcinoma.
Cancer research 1995;55(3):652-7.
1994: Masaaki Oka; Shoichi Hazama; M Suzuki; F Wang; K Shimoda; Norio Iizuka; K Wadamori; T Suzuki; S Attwood
Depression of cytotoxicity of nonparenchymal cells in the liver after surgery.
Surgery 1994;116(5):877-82.
1994: M Tsurumi; Masaaki Oka; Shoichi Hazama; Akira Tangoku; Y Hamanaka; T Suzuki
[A case report: multiple liver metastasis from gastric cancer responding to intraarterial infusion of sequential low-dose MTX and 5-FU].
Gan to kagaku ryoho. Cancer & chemotherapy 1994;21(13):2179-82.
1994: Masaaki Oka; T Suzuki
[Strategy of treatment for pancreatic and biliary cancer with special reference to immunotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 1994;21(10):1571-6.
1994: Masaaki Oka; Shoichi Hazama; S Yoshino; K Shimoda; M Suzuki; R Shimizu; K Yano; M Nishida; T Suzuki
Intraarterial combined immunochemotherapy for unresectable hepatocellular carcinoma: preliminary results.
Cancer immunology, immunotherapy : CII 1994;38(3):194-200.
1993: K Shimoda; Masaaki Oka; Shoichi Hazama; M Suzuki; N Lizuka; K Wadamori; F Wang; T Suzuki
[Augmentation of cytotoxicity of nonparenchymal cell of the liver after continuous IL-2 administration via the portal vein].
Gan to kagaku ryoho. Cancer & chemotherapy 1993;20(11):1567-9.
1993: Masaaki Oka; H Mitsunaga; Shoichi Hazama; S Yoshino; T Suzuki
Natural killer activity and serum immunosuppressive acidic protein levels in esophageal and gastric cancers.
Surgery today 1993;23(8):669-74.
1993: Masaaki Oka; S Yoshino; Shoichi Hazama; K Shimoda; T Suzuki
The characterization of peritoneal and pleural exudate cells from malignant effusions.
Surgery today 1993;23(6):500-3.
1992: M Tsurumi; Masaaki Oka; Shoichi Hazama; K Yano; T Uchiyama; T Suzuki
[A study of complications of hepatic arterial infusion catheter].
Gan to kagaku ryoho. Cancer & chemotherapy 1992;19(10 Suppl):1584-6.
1992: Masaaki Oka; S Yoshino; Shoichi Hazama; K Shimoda; T Suzuki
Immunological analysis and clinical effects of intraabdominal and intrapleural injection of lentinan for malignant ascites and pleural effusion.
Biotherapy (Dordrecht, Netherlands) 1992;5(2):107-12.
1991: Shoichi Hazama; H Hayashi; Masaaki Oka; T Murakami; T Suzuki
[Regional immunochemotherapy for liver metastasis of esophageal cancer in a patient with variant hepatic artery].
Gan to kagaku ryoho. Cancer & chemotherapy 1991;18(11):2002-6.
1991: K Shimoda; Shoichi Hazama; H Mitsunaga; T Uchiyama; Masaaki Oka; T Suzuki
[A case of recurrent pelvic tumor of sigmoid colon cancer showing partial response to lipiodolization].
Gan to kagaku ryoho. Cancer & chemotherapy 1991;18(11):1951-4.
1990: S Yoshino; Masaaki Oka; Shoichi Hazama; T Suzuki
[Effect of intrapleural and/or intraperitoneal lentinan therapy in carcinomatous pleuritis and peritonitis].
Gan to kagaku ryoho. Cancer & chemotherapy 1990;17(8 Pt 2):1588-91.
1990: Shoichi Hazama; Masaaki Oka; R Shimizu; K Yano; S Yoshino; Norio Iizuka; T Murakami; T Suzuki
[Intraarterial combination immunotherapy in hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 1990;17(8 Pt 2):1638-42.