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Masaru Okabe

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Anatomy

Chemicals & Drugs

Physiology

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Molecular Sequence Data

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Fertilization

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Publications

TOP 3
Tokuhiro Keizo; Isotani Ayako; Yokota Sadaki; Yano Yoshihisa; Oshio Shigeru; Hirose Mika; Wada Morimasa; Fujita Kyoko; Ogawa Yukiko; Okabe Masaru; Nishimune Yoshitake; Tanaka Hiromitsu
OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse.
Kokubu Chikara; Horie Kyoji; Abe Koichiro; Ikeda Ryuji; Mizuno Sumi; Uno Yoshihiro; Ogiwara Sanae; Ohtsuka Masato; Isotani Ayako; Okabe Masaru; Imai Kenji; Takeda Junji
A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice.
Nimura Keisuke; Ura Kiyoe; Shiratori Hidetaka; Ikawa Masato; Okabe Masaru; Schwartz Robert J; Kaneda Yasufumi
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.

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All Publications

2009: Tokuhiro Keizo; Isotani Ayako; Yokota Sadaki; Yano Yoshihisa; Oshio Shigeru; Hirose Mika; Wada Morimasa; Fujita Kyoko; Ogawa Yukiko; Okabe Masaru; Nishimune Yoshitake; Tanaka Hiromitsu
OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse.
PLoS genetics 2009;5(11):e1000712.
2009: Kokubu Chikara; Horie Kyoji; Abe Koichiro; Ikeda Ryuji; Mizuno Sumi; Uno Yoshihiro; Ogiwara Sanae; Ohtsuka Masato; Isotani Ayako; Okabe Masaru; Imai Kenji; Takeda Junji
A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice.
Nature genetics 2009;41(8):946-52.
2009: Nimura Keisuke; Ura Kiyoe; Shiratori Hidetaka; Ikawa Masato; Okabe Masaru; Schwartz Robert J; Kaneda Yasufumi
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
Nature 2009;460(7252):287-91.
2009: Yamaguchi Ryo; Muro Yuko; Isotani Ayako; Tokuhiro Keizo; Takumi Kazuhiro; Adham Ibrahim; Ikawa Masahito; Okabe Masaru
Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse.
Biology of reproduction 2009;81(1):142-6.
2009: Okada Yuka; Ueshin Yuko; Hasuwa Hidetoshi; Takumi Kazuhiro; Okabe Masaru; Ikawa Masahito
Targeted gene modification in mouse ES cells using integrase-defective lentiviral vectors.
Genesis (New York, N.Y. : 2000) 2009;47(4):217-23.
2008: Inoue Naokazu; Ikawa Masahito; Okabe Masaru
Putative sperm fusion protein IZUMO and the role of N-glycosylation.
Biochemical and biophysical research communications 2008;377(3):910-4.
2008: Yamaguchi Ryo; Yamagata Kazuo; Hasuwa Hidetoshi; Inano Emiko; Ikawa Masahito; Okabe Masaru
Cd52, known as a major maturation-associated sperm membrane antigen secreted from the epididymis, is not required for fertilization in the mouse.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(8):851-61.
2008: Tokuhiro Keizo; Hirose Mika; Miyagawa Yasushi; Tsujimura Akira; Irie Shinji; Isotani Ayako; Okabe Masaru; Toyama Yoshiro; Ito Chizuru; Toshimori Kiyotaka; Takeda Ken; Oshio Shigeru; Tainaka Hitoshi; Tsuchida Junji; Okuyama Akihiko; Nishimune Yoshitake; Tanaka Hiromitsu
Meichroacidin containing the membrane occupation and recognition nexus motif is essential for spermatozoa morphogenesis.
The Journal of biological chemistry 2008;283(27):19039-48.
2008: Ito Takashi; Kimura Yasushi; Uozumi Yoriko; Takai Mika; Muraoka Satoko; Matsuda Takahisa; Ueki Kei; Yoshiyama Minoru; Ikawa Masahito; Okabe Masaru; Schaffer Stephen W; Fujio Yasushi; Azuma Junichi
Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy.
Journal of molecular and cellular cardiology 2008;44(5):927-37.
2008: Kuramochi-Miyagawa Satomi; Watanabe Toshiaki; Gotoh Kengo; Totoki Yasushi; Toyoda Atsushi; Ikawa Masahito; Asada Noriko; Kojima Kanako; Yamaguchi Yuka; Ijiri Takashi W; Hata Kenichiro; Li En; Matsuda Yoichi; Kimura Tohru; Okabe Masaru; Sakaki Yoshiyuki; Sasaki Hiroyuki; Nakano Toru
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.
Genes & development 2008;22(7):908-17.
2008: Sato Takahiro; Kurokawa Mamoru; Nakashima Yoshiki; Ida Takanori; Takahashi Tomoko; Fukue Yoshihiko; Ikawa Masahito; Okabe Masaru; Kangawa Kenji; Kojima Masayasu
Ghrelin deficiency does not influence feeding performance.
Regulatory peptides 2008;145(1-3):7-11.
2008: Inoue Naokazu; Okabe Masaru
Sperm-egg fusion assay in mammals.
Methods in molecular biology (Clifton, N.J.) 2008;475():335-45.
2008: Ikawa Masahito; Inoue Naokazu; Okabe Masaru
Mechanisms of sperm-egg interactions emerging from gene-manipulated animals.
The International journal of developmental biology 2008;52(5-6):657-64.
2007: Yahata Kazuhide; Maeshima Kazuhiro; Sone Takefumi; Ando Taichi; Okabe Masaru; Imamoto Naoko; Imamoto Fumio
cHS4 insulator-mediated alleviation of promoter interference during cell-based expression of tandemly associated transgenes.
Journal of molecular biology 2007;374(3):580-90.
2007: Umehara Hiroki; Kimura Tohru; Ohtsuka Satoshi; Nakamura Toshinobu; Kitajima Kenji; Ikawa Masahito; Okabe Masaru; Niwa Hitoshi; Nakano Toru
Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase-3.
Stem cells (Dayton, Ohio) 2007;25(11):2705-11.
2007: Tsujikawa Kazutake; Yayama Katsutoshi; Hayashi Tamon; Matsushita Hiroaki; Yamaguchi Taijiro; Shigeno Tomomi; Ogitani Yusuke; Hirayama Megumi; Kato Tetsuya; Fukada So-ichiro; Takatori Shingo; Kawasaki Hiromu; Okamoto Hiroshi; Ikawa Masahito; Okabe Masaru; Yamamoto Hiroshi
Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16702-7.
2007: Ueda Yasutaka; Yamaguchi Ryo; Ikawa Masahito; Okabe Masaru; Morii Eiichi; Maeda Yusuke; Kinoshita Taroh
PGAP1 knock-out mice show otocephaly and male infertility.
The Journal of biological chemistry 2007;282(42):30373-80.
2007: Okabe M; Cummins J M
Mechanisms of sperm-egg interactions emerging from gene-manipulated animals.
Cellular and molecular life sciences : CMLS 2007;64(15):1945-58.
2007: Murayama K; Kimura T; Tarutani M; Tomooka M; Hayashi R; Okabe M; Nishida K; Itami S; Katayama I; Nakano T
Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors.
Oncogene 2007;26(33):4882-8.
2007: Yabuta Norikazu; Okada Nobuhiro; Ito Akihiko; Hosomi Toshiya; Nishihara Souichi; Sasayama Yuya; Fujimori Azumi; Okuzaki Daisuke; Zhao Hanjun; Ikawa Masahito; Okabe Masaru; Nojima Hiroshi
Lats2 is an essential mitotic regulator required for the coordination of cell division.
The Journal of biological chemistry 2007;282(26):19259-71.
2007: Okada Yuka; Ueshin Yuko; Isotani Ayako; Saito-Fujita Tomoko; Nakashima Hisako; Kimura Kazushi; Mizoguchi Akira; Oh-Hora Masatsugu; Mori Yoshiko; Ogata Masato; Oshima Robert G; Okabe Masaru; Ikawa Masahito
Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer.
Nature biotechnology 2007;25(2):233-7.
2007: Nakamura Toshinobu; Arai Yoshikazu; Umehara Hiroki; Masuhara Masaaki; Kimura Tohru; Taniguchi Hisaaki; Sekimoto Toshihiro; Ikawa Masahito; Yoneda Yoshihiro; Okabe Masaru; Tanaka Satoshi; Shiota Kunio; Nakano Toru
PGC7/Stella protects against DNA demethylation in early embryogenesis.
Nature cell biology 2007;9(1):64-71.
2007: Inoue Naokazu; Yamaguchi Ryo; Ikawa Masahito; Okabe Masaru
Sperm-egg interaction and gene manipulated animals.
Society of Reproduction and Fertility supplement 2007;65():363-71.
2006: Okabe Masaru
[Observation of sperm-egg interaction through gene-manipulated animals]
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(11):1062-72.
2006: Yamaguchi Ryo; Yamagata Kazuo; Ikawa Masahito; Moss Stuart B; Okabe Masaru
Aberrant distribution of ADAM3 in sperm from both angiotensin-converting enzyme (Ace)- and calmegin (Clgn)-deficient mice.
Biology of reproduction 2006;75(5):760-6.
2006: Nagamori Ippei; Yomogida Kentaro; Ikawa Masahito; Okabe Masaru; Yabuta Norikazu; Nojima Hiroshi
The testes-specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(10):1161-71.
2006: Takegahara Noriko; Takamatsu Hyota; Toyofuku Toshihiko; Tsujimura Tohru; Okuno Tatsusada; Yukawa Kazunori; Mizui Masayuki; Yamamoto Midori; Prasad Durbaka V R; Suzuki Kazuhiro; Ishii Masaru; Terai Kenta; Moriya Masayuki; Nakatsuji Yuji; Sakoda Saburo; Sato Shintaro; Akira Shizuo; Takeda Kiyoshi; Inui Masanori; Takai Toshiyuki; Ikawa Masahito; Okabe Masaru; Kumanogoh Atsushi; Kikutani Hitoshi
Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis.
Nature cell biology 2006;8(6):615-22.
2006: Watanabe S; Umehara H; Murayama K; Okabe M; Kimura T; Nakano T
Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells.
Oncogene 2006;25(19):2697-707.
2006: Zhao Hanjun; Ito Akihiko; Kimura Shinya H; Yabuta Norikazu; Sakai Naohiko; Ikawa Masahito; Okabe Masaru; Matsuzawa Yuji; Yamashita Shizuya; Nojima Hiroshi
RECS1 deficiency in mice induces susceptibility to cystic medial degeneration.
Genes & genetic systems 2006;81(1):41-50.
2006: Kobayashi Shin; Isotani Ayako; Mise Nathan; Yamamoto Masamichi; Fujihara Yoshitaka; Kaseda Kazuhiro; Nakanishi Tomoko; Ikawa Masahito; Hamada Hiroshi; Abe Kuniya; Okabe Masaru
Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages.
Current biology : CB 2006;16(2):166-72.
2005: Wang Xiangchun; Inoue Shinya; Gu Jianguo; Miyoshi Eiji; Noda Katsuhisa; Li Wenzhe; Mizuno-Horikawa Yoko; Nakano Miyako; Asahi Michio; Takahashi Motoko; Uozumi Naofumi; Ihara Shinji; Lee Seung Ho; Ikeda Yoshitaka; Yamaguchi Yukihiro; Aze Yoshiya; Tomiyama Yoshiaki; Fujii Junichi; Suzuki Keiichiro; Kondo Akihiro; Shapiro Steven D; Lopez-Otin Carlos; Kuwaki Tomoyuki; Okabe Masaru; Honke Koichi; Taniguchi Naoyuki
Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15791-6.
2005: Tanaka Hiromitsu; Iguchi Naoko; Isotani Ayako; Kitamura Kouichi; Toyama Yoshiro; Matsuoka Yasuhiro; Onishi Masayoshi; Masai Kumiko; Maekawa Mamiko; Toshimori Kiyotaka; Okabe Masaru; Nishimune Yoshitake
HANP1/H1T2, a novel histone H1-like protein involved in nuclear formation and sperm fertility.
Molecular and cellular biology 2005;25(16):7107-19.
2005: Yahata Kazuhide; Kishine Hiroe; Sone Takefumi; Sasaki Yukari; Hotta Junko; Chesnut Jonathan D; Okabe Masaru; Imamoto Fumio
Multi-gene gateway clone design for expression of multiple heterologous genes in living cells: conditional gene expression at near physiological levels.
Journal of biotechnology 2005;118(2):123-34.
2005: Kumanogoh Atsushi; Shikina Takashi; Suzuki Kazuhiro; Uematsu Satoshi; Yukawa Kazunori; Kashiwamura Shin-Ichiro; Tsutsui Hiroko; Yamamoto Midori; Takamatsu Hyota; Ko-Mitamura Elizabeth P; Takegahara Noriko; Marukawa Satoko; Ishida Isao; Morishita Hiroshi; Prasad Durbaka V R; Tamura Manabu; Mizui Masayuki; Toyofuku Toshihiko; Akira Shizuo; Takeda Kiyoshi; Okabe Masaru; Kikutani Hitoshi
Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice.
Immunity 2005;22(3):305-16.
2005: Inoue Naokazu; Ikawa Masahito; Isotani Ayako; Okabe Masaru
The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.
Nature 2005;434(7030):234-8.
2005: Isotani Ayako; Nakanishi Tomoko; Kobayashi Shin; Lee Jiyoung; Chuma Shinichiro; Nakatsuji Norio; Ishino Fumitoshi; Okabe Masaru
Genomic imprinting of XX spermatogonia and XX oocytes recovered from XX<-->XY chimeric testes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):4039-44.
2005: Kondoh Gen; Tojo Hiromasa; Nakatani Yuka; Komazawa Nobuyasu; Murata Chie; Yamagata Kazuo; Maeda Yusuke; Kinoshita Taroh; Okabe Masaru; Taguchi Ryo; Takeda Junji
Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization.
Nature medicine 2005;11(2):160-6.
2004: Hanada Reiko; Teranishi Hitoshi; Pearson James Todd; Kurokawa Mamoru; Hosoda Hiroshi; Fukushima Nobuhiro; Fukue Yoshihiko; Serino Ryota; Fujihara Hiroaki; Ueta Yoichi; Ikawa Masahito; Okabe Masaru; Murakami Noboru; Shirai Mikiyasu; Yoshimatsu Hironobu; Kangawa Kenji; Kojima Masayasu
Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway.
Nature medicine 2004;10(10):1067-73.
2004: Nakanishi Tomoko; Isotani Ayako; Yamaguchi Ryo; Ikawa Masahito; Baba Tadashi; Suarez Susan S; Okabe Masaru
Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice.
Biology of reproduction 2004;71(3):959-65.
2004: Matsumura Hiroyuki; Hasuwa Hidetoshi; Inoue Naokazu; Ikawa Masahito; Okabe Masaru
Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain.
Biochemical and biophysical research communications 2004;321(2):275-9.
2004: Iwatani Hirotsugu; Ito Takahito; Imai Enyu; Matsuzaki Yumi; Suzuki Akira; Yamato Masaya; Okabe Masaru; Hori Masatsugu
Hematopoietic and nonhematopoietic potentials of Hoechst(low)/side population cells isolated from adult rat kidney.
Kidney international 2004;65(5):1604-14.
2004: Kuramochi-Miyagawa Satomi; Kimura Tohru; Ijiri Takashi W; Isobe Taku; Asada Noriko; Fujita Yukiko; Ikawa Masahito; Iwai Naomi; Okabe Masaru; Deng Wei; Lin Haifan; Matsuda Yoichi; Nakano Toru
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.
Development (Cambridge, England) 2004;131(4):839-49.
2004: Suzuki Akira; Iwatani Hirotsugu; Ito Takahito; Imai Enyu; Okabe Masaru; Nakamura Hiroyuki; Isaka Yoshitaka; Yamato Masaya; Hori Masatsugu
Platelet-derived growth factor plays a critical role to convert bone marrow cells into glomerular mesangial-like cells.
Kidney international 2004;65(1):15-24.
2004: Hasuwa Hidetoshi; Okabe Masaru
RNAi in living mice.
Methods in molecular biology (Clifton, N.J.) 2004;252():501-8.
2003: Tadokoro Yuko; Yomogida Kentaro; Yagura Yo; Yamada Shuichi; Okabe Masaru; Nishimune Yoshitake
Characterization of histone H2A.X expression in testis and specific labeling of germ cells at the commitment stage of meiosis with histone H2A.X promoter-enhanced green fluorescent protein transgene.
Biology of reproduction 2003;69(4):1325-9.
2003: Yamamoto Masahiro; Sato Shintaro; Hemmi Hiroaki; Hoshino Katsuaki; Kaisho Tsuneyasu; Sanjo Hideki; Takeuchi Osamu; Sugiyama Masanaka; Okabe Masaru; Takeda Kiyoshi; Akira Shizuo
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.
Science (New York, N.Y.) 2003;301(5633):640-3.
2003: Azukizawa Hiroaki; Kosaka Hiroshi; Sano Shigetoshi; Heath William R; Takahashi Isao; Gao Xing-Hua; Sumikawa Yasuyuki; Okabe Masaru; Yoshikawa Kunihiko; Itami Satoshi
Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes.
European journal of immunology 2003;33(7):1879-88.
2003: Kimura Tohru; Ito Chizuru; Watanabe Shoko; Takahashi Tohru; Ikawa Masahito; Yomogida Kentaro; Fujita Yukiko; Ikeuchi Megumi; Asada Noriko; Matsumiya Kiyomi; Okuyama Akihiko; Okabe Masaru; Toshimori Kiyotaka; Nakano Toru
Mouse germ cell-less as an essential component for nuclear integrity.
Molecular and cellular biology 2003;23(4):1304-15.
2003: Nagashima H; Fujimura T; Takahagi Y; Kurome M; Wako N; Ochiai T; Esaki R; Kano K; Saito S; Okabe M; Murakami H
Development of efficient strategies for the production of genetically modified pigs.
Theriogenology 2003;59(1):95-106.
2003: Sakuma Takahiko; Higashibata Yuji; Kawahata Hirohisa; Yamada Shuichi; Okabe Masaru; Kitamura Yukihiko; Nomura Shintaro
Difference of osteopontin gene regulation between bone and kidney.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2003;8(3):361-6.
2002: Nakanishi Tomoko; Kuroiwa Asato; Yamada Shuichi; Isotani Ayako; Yamashita Atsuko; Tairaka Ai; Hayashi Tamon; Takagi Tatsuya; Ikawa Masahito; Matsuda Yoichi; Okabe Masaru
FISH analysis of 142 EGFP transgene integration sites into the mouse genome.
Genomics 2002;80(6):564-74.
2002: Hasuwa Hidetoshi; Kaseda Kazuhiro; Einarsdottir Thorbjorg; Okabe Masaru
Small interfering RNA and gene silencing in transgenic mice and rats.
FEBS letters 2002;532(1-2):227-30.
2002: Murakami Yoshiko; Kosaka Hiroshi; Maeda Yusuke; Nishimura Jun-ichi; Inoue Norimitsu; Ohishi Kazuhito; Okabe Masaru; Takeda Junji; Kinoshita Taroh
Inefficient response of T lymphocytes to glycosylphosphatidylinositol anchor-negative cells: implications for paroxysmal nocturnal hemoglobinuria.
Blood 2002;100(12):4116-22.
2002: Yokoyama Chieko; Yabuki Tomoko; Shimonishi Manabu; Wada Masayuki; Hatae Toshihisa; Ohkawara Susumu; Takeda Junji; Kinoshita Taroh; Okabe Masaru; Tanabe Tadashi
Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction.
Circulation 2002;106(18):2397-403.
2002: Yamagata Kazuo; Nakanishi Tomoko; Ikawa Masahito; Yamaguchi Ryou; Moss Stuart B; Okabe Masaru
Sperm from the calmegin-deficient mouse have normal abilities for binding and fusion to the egg plasma membrane.
Developmental biology 2002;250(2):348-57.
2002: Gao Xing-Hua; Kondoh Gen; Tarutani Masahito; Hara Mariko; Inoue Shintaro; Nakanishi Tomoko; Okabe Masaru; Yamaguchi Yuji; Yoshikawa Kunihiko; Itami Satoshi; Takeda Junji
Rapid compensation for glycosylphosphatidylinositol anchor deficient keratinocytes after birth: visualization of glycosylphosphatidylinositol-anchored proteins in situ.
The Journal of investigative dermatology 2002;118(6):998-1002.
2002: Murakami Hiroshi; Nagashima Hiroshi; Takahagi Yoichi; Miyagawa Shuji; Fujimura Tatsuya; Toyomura Koji; Nakai Rie; Yamada Mako; Kurihara Takashi; Shigehisa Tamotsu; Okabe Masaru; Seya Tsukasa; Shirakura Ryota; Kinoshita Taroh
Transgenic pigs expressing human decay-accelerating factor regulated by porcine MCP gene promoter.
Molecular reproduction and development 2002;61(3):302-11.
2002: Osugi Tomoaki; Oshima Yuichi; Fujio Yasushi; Funamoto Masanobu; Yamashita Atsuko; Negoro Shinji; Kunisada Keita; Izumi Masahiro; Nakaoka Yoshikazu; Hirota Hisao; Okabe Masaru; Yamauchi-Takihara Keiko; Kawase Ichiro; Kishimoto Tadamitsu
Cardiac-specific activation of signal transducer and activator of transcription 3 promotes vascular formation in the heart.
The Journal of biological chemistry 2002;277(8):6676-81.
2002: Tohda Akira; Okuno Tsuyoshi; Matsumiya Kiyomi; Okabe Masaru; Kishikawa Hidefumi; Dohmae Kayoko; Okuyama Akihiko; Nishimune Yoshitake
Restoration of spermatogenesis and fertility in azoospermic mutant mice by suppression and reelevation of testosterone followed by intracytoplasmic sperm injection.
Biology of reproduction 2002;66(1):85-90.
2001: Ikawa M; Nakanishi T; Yamada S; Wada I; Kominami K; Tanaka H; Nozaki M; Nishimune Y; Okabe M
Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility.
Developmental biology 2001;240(1):254-61.
2001: Ito T; Suzuki A; Imai E; Okabe M; Hori M
Bone marrow is a reservoir of repopulating mesangial cells during glomerular remodeling.
Journal of the American Society of Nephrology : JASN 2001;12(12):2625-35.
2001: Watanabe C; Kumanogoh A; Shi W; Suzuki K; Yamada S; Okabe M; Yoshida K; Kikutani H
Enhanced immune responses in transgenic mice expressing a truncated form of the lymphocyte semaphorin CD100.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4321-8.
2001: Miyagawa S; Murakami H; Takahagi Y; Nakai R; Yamada M; Murase A; Koyota S; Koma M; Matsunami K; Fukuta D; Fujimura T; Shigehisa T; Okabe M; Nagashima H; Shirakura R; Taniguchi N
Remodeling of the major pig xenoantigen by N-acetylglucosaminyltransferase III in transgenic pig.
The Journal of biological chemistry 2001;276(42):39310-9.
2001: Nakanishi T; Ikawa M; Yamada S; Toshimori K; Okabe M
Alkalinization of acrosome measured by GFP as a pH indicator and its relation to sperm capacitation.
Developmental biology 2001;237(1):222-31.
2001: Horie K; Kuroiwa A; Ikawa M; Okabe M; Kondoh G; Matsuda Y; Takeda J
Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(16):9191-6.
2001: Kimura S H; Ikawa M; Ito A; Okabe M; Nojima H
Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery.
Oncogene 2001;20(25):3290-300.
2001: Miyagawa S; Yamada M; Matsunami K; Koresawa Y; Ikawa M; Okabe M; Shirakura R
A synthetic dDAF (CD55) gene based on optimal codon usage for transgenic animals.
Journal of biochemistry 2001;129(5):795-801.
2001: Tamatani M; Matsuyama T; Yamaguchi A; Mitsuda N; Tsukamoto Y; Taniguchi M; Che Y H; Ozawa K; Hori O; Nishimura H; Yamashita A; Okabe M; Yanagi H; Stern D M; Ogawa S; Tohyama M
ORP150 protects against hypoxia/ischemia-induced neuronal death.
Nature medicine 2001;7(3):317-23.
2001: Tashiro Y; Miyahara M; Shirasaki R; Okabe M; Heizmann C W; Murakami F
Local nonpermissive and oriented permissive cues guide vestibular axons to the cerebellum.
Development (Cambridge, England) 2001;128(6):973-81.
2001: Yamada M; Miyagawa S; Matsunami K; Koresawa Y; Kurihara T; Ikawa M; Okabe M; Shirakura R
A codon exchange DAF is a powerful material for xenografting.
Transplantation proceedings 2001;33(1-2):744-5.
2001: Suzuki A; Hanada T; Mitsuyama K; Yoshida T; Kamizono S; Hoshino T; Kubo M; Yamashita A; Okabe M; Takeda K; Akira S; Matsumoto S; Toyonaga A; Sata M; Yoshimura A
CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation.
The Journal of experimental medicine 2001;193(4):471-81.
2001: Ito T; Suzuki A; Okabe M; Imai E; Hori M
Application of bone marrow-derived stem cells in experimental nephrology.
Experimental nephrology 2001;9(6):444-50.
2000: Koresawa Y; Miyagawa S; Ikawa M; Matsunami K; Yamada M; Okabe M; Shirakura R
A new Cre recombinase gene based on optimal codon usage in mammals: a powerful material for organ-specific gene targeting.
Transplantation proceedings 2000;32(7):2516-7.
2000: Murakami H; Nagashima H; Takahagi Y; Fujimura T; Miyagawa S; Okabe M; Seya T; Shigehisa T; Taniguchi N; Shirakura R; Kinoshita T
Production of transgenic pigs expressing human DAF (CD55) regulated by the porcine MCP gene promoter.
Transplantation proceedings 2000;32(7):2505-6.
2000: Shi W; Kumanogoh A; Watanabe C; Uchida J; Wang X; Yasui T; Yukawa K; Ikawa M; Okabe M; Parnes J R; Yoshida K; Kikutani H
The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice.
Immunity 2000;13(5):633-42.
2000: Yoneda T; Imaizumi K; Maeda M; Yui D; Manabe T; Katayama T; Sato N; Gomi F; Morihara T; Mori Y; Miyoshi K; Hitomi J; Ugawa S; Yamada S; Okabe M; Tohyama M
Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein.
The Journal of biological chemistry 2000;275(15):11114-20.
2000: Koresawa Y; Miyagawa S; Ikawa M; Matsunami K; Yamada M; Shirakura R; Okabe M
Synthesis of a new Cre recombinase gene based on optimal codon usage for mammalian systems.
Journal of biochemistry 2000;127(3):367-72.
2000: Miyado K; Yamada G; Yamada S; Hasuwa H; Nakamura Y; Ryu F; Suzuki K; Kosai K; Inoue K; Ogura A; Okabe M; Mekada E
Requirement of CD9 on the egg plasma membrane for fertilization.
Science (New York, N.Y.) 2000;287(5451):321-4.
2000: Kunisada K; Negoro S; Tone E; Funamoto M; Osugi T; Yamada S; Okabe M; Kishimoto T; Yamauchi-Takihara K
Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):315-9.
1999: Kawakami N; Sakane N; Nishizawa F; Iwao M; Fukada S I; Tsujikawa K; Kohama Y; Ikawa M; Okabe M; Yamamoto H
Green fluorescent protein-transgenic mice: immune functions and their application to studies of lymphocyte development.
Immunology letters 1999;70(3):165-71.
1999: Kondoh G; Gao X H; Nakano Y; Koike H; Yamada S; Okabe M; Takeda J
Tissue-inherent fate of GPI revealed by GPI-anchored GFP transgenesis.
FEBS letters 1999;458(3):299-303.
1999: Kawakami N; Nishizawa F; Sakane N; Iwao M; Tsujikawa K; Ikawa M; Okabe M; Yamamoto H
Roles of integrins and CD44 on the adhesion and migration of fetal liver cells to the fetal thymus.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3211-6.
1999: Matsumoto A; Seki Y; Kubo M; Ohtsuka S; Suzuki A; Hayashi I; Tsuji K; Nakahata T; Okabe M; Yamada S; Yoshimura A
Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice.
Molecular and cellular biology 1999;19(9):6396-407.
1999: Nakanishi T; Ikawa M; Yamada S; Parvinen M; Baba T; Nishimune Y; Okabe M
Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein.
FEBS letters 1999;449(2-3):277-83.
1999: Imai E; Akagi Y; Isaka Y; Ikawa M; Takenaka M; Hori M; Okabe M
Glowing podocytes in living mouse: transgenic mouse carrying a podocyte-specific promoter.
Experimental nephrology 1999;7(1):63-6.
1998: Mikata S; Miyagawa S; Yoshitatsu M; Ikawa M; Okabe M; Matsuda H; Shirakura R
Prevention of hyperacute rejection by phosphatidylinositol-anchored mini-complement receptor type 1.
Transplant immunology 1998;6(2):107-10.
1998: Ikawa M; Yamada S; Nakanishi T; Okabe M
'Green mice' and their potential usage in biological research.
FEBS letters 1998;430(1-2):83-7.
1997: Tanaka H; Ikawa M; Tsuchida J; Nozaki M; Suzuki M; Fujiwara T; Okabe M; Nishimune Y
Cloning and characterization of the human Calmegin gene encoding putative testis-specific chaperone.
Gene 1997;204(1-2):159-63.
1997: Kojima Y; Kominami K; Dohmae K; Nonomura N; Miki T; Okuyama A; Nishimune Y; Okabe M
Cessation of spermatogenesis in juvenile spermatogonial depletion (jsd/jsd) mice.
International journal of urology : official journal of the Japanese Urological Association 1997;4(5):500-7.
1997: Tarutani M; Itami S; Okabe M; Ikawa M; Tezuka T; Yoshikawa K; Kinoshita T; Takeda J
Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7400-5.
1997: Ikawa M; Wada I; Kominami K; Watanabe D; Toshimori K; Nishimune Y; Okabe M
The putative chaperone calmegin is required for sperm fertility.
Nature 1997;387(6633):607-11.
1997: Okabe M; Ikawa M; Kominami K; Nakanishi T; Nishimune Y
'Green mice' as a source of ubiquitous green cells.
FEBS letters 1997;407(3):313-9.
1997: Miyagawa S; Mikata S; Tanaka H; Ikawa M; Kominami K; Seya T; Nishimune Y; Shirakura R; Okabe M
The regulation of membrane cofactor protein (CD46) expression by the 3' untranslated region in transgenic mice.
Biochemical and biophysical research communications 1997;233(3):829-33.
1997: Akagi Y; Isaka Y; Akagi A; Ikawa M; Takenaka M; Moriyama T; Yamauchi A; Horio M; Ueda N; Okabe M; Imai E
Transcriptional activation of a hybrid promoter composed of cytomegalovirus enhancer and beta-actin/beta-globin gene in glomerular epithelial cells in vivo.
Kidney international 1997;51(4):1265-9.
1997: Miyagawa S; Ikawa M; Kominami K; Tanaka H; Mikata S; Matsuda H; Seya T; Shirakura R; Okabe M
The regulation of membrane cofactor protein (CD46) expression in transgenic mice: the importance of the first 125 BP of the 3' untranslated region.
Transplantation proceedings 1997;29(1-2):941-2.
1996: Kitayama H; Tsujimura T; Matsumura I; Oritani K; Ikeda H; Ishikawa J; Okabe M; Suzuki M; Yamamura K; Matsuzawa Y; Kitamura Y; Kanakura Y
Neoplastic transformation of normal hematopoietic cells by constitutively activating mutations of c-kit receptor tyrosine kinase.
Blood 1996;88(3):995-1004.
1996: Kawagoe K; Kitamura D; Okabe M; Taniuchi I; Ikawa M; Watanabe T; Kinoshita T; Takeda J
Glycosylphosphatidylinositol-anchor-deficient mice: implications for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria.
Blood 1996;87(9):3600-6.
1996: Miyagawa S; Ikawa M; Kominami K; Yoshimura Y; Tanaka H; Mikata S; Shirakura R; Matsuda H; Yanagi Y; Seya T; Okabe M
Difference of expression levels between gene technological product delta CYT-MCP(CD46) and intact MCP(CD46) in transgenic mice.
Transplantation proceedings 1996;28(2):585-6.
1996: Miyagawa S; Mikata M; Matsuda H; Ikawa M; Okabe M; Nagasawa S; Matsumoto M; Seya T; Shirakura R
In vitro and in vivo studies to prevent hyperacute rejection.
Transplantation proceedings 1996;28(2):1031-3.
1995: Muto N; Dota A; Tanaka T; Itoh N; Okabe M; Inada A; Nakanishi T; Tanaka K
Hinokitiol induces differentiation of teratocarcinoma F9 cells.
Biological & pharmaceutical bulletin 1995;18(11):1576-9.
1995: Ikawa M; Kominami K; Yoshimura Y; Tanaka K; Nishimune Y; Okabe M
A rapid and non-invasive selection of transgenic embryos before implantation using green fluorescent protein (GFP).
FEBS letters 1995;375(1-2):125-8.
1995: Watanabe D; Okabe M; Hamajima N; Morita T; Nishina Y; Nishimune Y
Characterization of the testis-specific gene 'calmegin' promoter sequence and its activity defined by transgenic mouse experiments.
FEBS letters 1995;368(3):509-12.
1995: Ikawa M; Ying X; Tanaka K; Ohashi K; Saji F; Okabe M
Improvement of fusing ability of human sperm to zona-free hamster eggs by conditioned media.
Biological & pharmaceutical bulletin 1995;18(1):5-8.
1994: Dohmae K; Okabe M; Nishimune Y
Experimental transmission of hantavirus infection in laboratory rats.
The Journal of infectious diseases 1994;170(6):1589-92.
1994: Ohashi K; Saji F; Wakimoto A; Tsutsui T; Nakazawa T; Okabe M; Mimura T; Tanizawa O
Selection of acrosome-reacted sperm with MH61-immunobeads.
Journal of andrology 1994;15(1):78-82.
1993: Ikawa M; Okabe M
[What does sperm recognize on fusing cells?]
Seikagaku. The Journal of Japanese Biochemical Society 1993;65(11):1429-33.
1993: Ying X; Okabe M; Mimura T
Selection of acrosome-reacted human spermatozoa and their fusing ability by micro-injection into the perivitelline space of hamster eggs.
Human reproduction (Oxford, England) 1993;8(7):1074-8.
1993: Okabe M; Kishi Y; Ying X; Kohama Y; Mimura T; Li S S
Characterization of capacitation inhibitory protein from rabbit seminal plasma: homology with human annexins.
Biological & pharmaceutical bulletin 1993;16(5):453-6.
1993: Noguchi T; Okabe M; Wang Z; Yamada K; Imai E; Tanaka T
An enhancer unit of L-type pyruvate kinase gene is responsible for transcriptional stimulation by dietary fructose as well as glucose in transgenic mice.
FEBS letters 1993;318(3):269-72.
1992: Ohashi K; Saji F; Kato M; Okabe M; Mimura T; Tanizawa O
Evaluation of acrosomal status using MH61-beads test and its clinical application.
Fertility and sterility 1992;58(4):803-8.
1992: Okabe M; Matzno S; Nagira M; Ying X; Kohama Y; Mimura T
Collection of acrosome-reacted human sperm using monoclonal antibody-coated paramagnetic beads.
Molecular reproduction and development 1992;32(4):389-93.
1992: Okabe M; Ying X; Nagira M; Ikawa M; Kohama Y; Mimura T; Tanaka K
Homology of an acrosome-reacted sperm-specific antigen to CD46.
Journal of pharmacobio-dynamics 1992;15(8):455-9.
1990: Okabe M; Nagira M; Kawai Y; Matzno S; Mimura T; Mayumi T
A human sperm antigen possibly involved in binding and/or fusion with zona-free hamster eggs.
Fertility and sterility 1990;54(6):1121-6.
1989: Kohama Y; Miyamoto T; Oka H; Yamamoto K; Murayama N; Tsujikawa K; Okabe M; Mimura T
Enhancement of heparin-binding ability of fibronectin by S-carboxamide-methylation.
Journal of pharmacobio-dynamics 1989;12(10):626-33.
1989: Kawai Y; Hama T; Mayumi T; Okabe M; Matzno S; Kohama Y; Mimura T
Flow cytometric analysis of mouse sperm using monoclonal anti-sperm antibody OBF13.
Journal of reproductive immunology 1989;16(1):71-82.
1989: Kohama Y; Oka H; Yamamoto K; Teramoto T; Okabe M; Mimura T; Nagase Y; Chiba Y; Fujita T
Induction of angiotensin-converting enzyme inhibitory activity by acid-limited proteolysis of glyceraldehyde 3-phosphate dehydrogenase.
Biochemical and biophysical research communications 1989;161(2):456-60.
1989: Mimura T; Tsujikawa K; Yasuda N; Nakajima H; Lee B G; Okabe M; Kohama Y
Studies on pharmacological activation of human serum immunoglobulin G by chemical modification and active subfragments. VIII. Effect of carboxamide-methylated light chain (Fr.I-L) on leukocyte functions.
Journal of pharmacobio-dynamics 1989;12(3):159-63.
1989: Okabe M; Yagasaki M; Matzno S; nagira M; Kohama Y; Mimura T
Glucosamine enhanced sperm-egg binding but inhibited sperm-egg fusion in mouse.
Experientia 1989;45(2):193-4.
1988: Kohama Y; Matsumoto S; Oka H; Teramoto T; Okabe M; Mimura T
Isolation of angiotensin-converting enzyme inhibitor from tuna muscle.
Biochemical and biophysical research communications 1988;155(1):332-7.
1988: Okabe M; Yagasaki M; Oda H; Matzno S; Kohama Y; Mimura T
Effect of a monoclonal anti-mouse sperm antibody (OBF13) on the interaction of mouse sperm with zona-free mouse and hamster eggs.
Journal of reproductive immunology 1988;13(3):211-9.
1988: Mimura T; Tsujikawa K; Yasuda N; Nakajima H; Haruyama M; Ohmura T; Okabe M
Suppression of gastric ulcer induced by stress and HCL-ethanol by intravenously administered metallothionein-II.
Biochemical and biophysical research communications 1988;151(2):725-9.
1987: Okabe M; Adachi T; Takada K; Oda H; Yagasaki M; Kohama Y; Mimura T
Capacitation-related changes in antigen distribution on mouse sperm heads and its relation to fertilization rate in vitro.
Journal of reproductive immunology 1987;11(2):91-100.

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