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Yuji Okada

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Akira Yasuda; Yoichi Matsuo; Nobuo Ochi; Yuji Okada; Hirozumi Sawai; Hiromitsu Takeyama
Solid variant of serous cystadenoma of the pancreas.
Donghui Xu; Yoichi Matsuo; Jiachi Ma; Shuji Koide; Nobuo Ochi; Akira Yasuda; Hitoshi Funahashi; Yuji Okada; Hiromitsu Takeyama
Cancer cell-derived IL-1α promotes HGF secretion by stromal cells and enhances metastatic potential in pancreatic cancer cells.
Satoru Takayama; Hiroki Takahashi; Yoichi Matsuo; Yuji Okada; Hiromitsu Takeyama
Effect of Helicobacter bilis infection on human bile duct cancer cells.

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All Publications

2011: Akira Yasuda; Yoichi Matsuo; Nobuo Ochi; Yuji Okada; Hirozumi Sawai; Hiromitsu Takeyama
Solid variant of serous cystadenoma of the pancreas.
Archives of medical science : AMS 2011;7(2):353-5.
2010: Donghui Xu; Yoichi Matsuo; Jiachi Ma; Shuji Koide; Nobuo Ochi; Akira Yasuda; Hitoshi Funahashi; Yuji Okada; Hiromitsu Takeyama
Cancer cell-derived IL-1α promotes HGF secretion by stromal cells and enhances metastatic potential in pancreatic cancer cells.
Journal of surgical oncology 2010;102(5):469-77.
2010: Satoru Takayama; Hiroki Takahashi; Yoichi Matsuo; Yuji Okada; Hiromitsu Takeyama
Effect of Helicobacter bilis infection on human bile duct cancer cells.
Digestive diseases and sciences 2010;55(7):1905-10.
2008: Jiachi Ma; Hirozumi Sawai; Yoichi Matsuo; Nobuo Ochi; Akira Yasuda; Hiroki Takahashi; Takehiro Wakasugi; Hitoshi Funahashi; Mikinori Sato; Yuji Okada; Hiromitsu Takeyama; Tadao Manabe
Interleukin-1alpha enhances angiogenesis and is associated with liver metastatic potential in human gastric cancer cell lines.
The Journal of surgical research 2008;148(2):197-204.
2008: Takayuki Saito; Miki Asano; Norikazu Nomura; Michiko Ishida; Akihiro Mizuno; Takuya Nakayama; Yuji Okada; Akira Mishima
Surgical treatment for infected thrombus in the superior vena cava using an off-pump venoatrial shunt.
The Annals of thoracic surgery 2008;85(3):1113-4.
2008: Hitoshi Funahashi; Yuji Okada; Hirozumi Sawai; Takehiro Wakasugi; Yoshimi Akamo; Tadao Manabe
Complete extragastric growth in a giant gastrointestinal stromal tumor: report of a case.
International surgery 2008;93(1):45-9.
2008: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Hiroki Takahashi; Yoichi Matsuo; Akira Yasuda; Nobuo Ochi; Hiromitsu Takeyama; Tadao Manabe
Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells.
The Journal of surgical research 2008;144(1):117-23.
2007: Satoru Takayama; Hiroki Takahashi; Yoichi Matsuo; Yuji Okada; Tadao Manabe
Effects of Helicobacter pylori infection on human pancreatic cancer cell line.
Hepato-gastroenterology 2007;54(80):2387-91.
2007: Hiroki Takahashi; Hitoshi Funahashi; Hirozumi Sawai; Yoichi Matsuo; Minoru Yamamoto; Yuji Okada; Hiromitsu Takeyama; Tadao Manabe
Synthetic serine protease inhibitor, gabexate mesilate, prevents nuclear factor-kappaB activation and increases TNF-alpha-mediated apoptosis in human pancreatic cancer cells.
Digestive diseases and sciences 2007;52(10):2646-52.
2007: Akira Yasuda; Hirozumi Sawai; Hiroki Takahashi; Nobuo Ochi; Yoichi Matsuo; Hitoshi Funahashi; Mikinori Sato; Yuji Okada; Hiromitsu Takeyama; Tadao Manabe
Stem cell factor/c-kit receptor signaling enhances the proliferation and invasion of colorectal cancer cells through the PI3K/Akt pathway.
Digestive diseases and sciences 2007;52(9):2292-300.
2007: Akiyoshi Furuta; Hitoshi Funahashi; Hirozumi Sawai; Mikinori Sato; Yuji Okada; Hiromitsu Takeyama; Tadao Manabe
The relationship between GDNF and integrins in human colorectal cancer cell activity.
Hepato-gastroenterology 2007;54(77):1398-402.
2007: Takahisa Hirokawa; Tetsushi Hayakawa; Moritsugu Tanaka; Yuji Okada; Hirozumi Sawai; Hiromitsu Takeyama; Tadao Manabe
Laparoscopic surgery for diagnosis and treatment of bowel obstruction: case report of paracecal hernia.
Medical science monitor : international medical journal of experimental and clinical research 2007;13(7):CS79-82.
2007: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Yoichi Matsuo; Tetsushi Hayakawa; Moritsugu Tanaka; Hiromitsu Takeyama; Tadao Manabe
Gastrointestinal stromal tumor of the rectum with liver metastasis: report of a case.
Hepato-gastroenterology 2007;54(76):1113-5.
2007: Nobuo Ochi; Yoichi Matsuo; Hirozumi Sawai; Akira Yasuda; Hiroki Takahashi; Mikinori Sato; Hitoshi Funahashi; Yuji Okada; Tadao Manabe
Vascular endothelial growth factor-C secreted by pancreatic cancer cell line promotes lymphatic endothelial cell migration in an in vitro model of tumor lymphangiogenesis.
Pancreas 2007;34(4):444-51.
2007: Hiromitsu Takeyama; Hirozumi Sawai; Takehiro Wakasugi; Hiroki Takahashi; Yoichi Matsuo; Nobuo Ochi; Akira Yasuda; Mikinori Sato; Yuji Okada; Hitoshi Funahashi; Yoshimi Akamo; Tadao Manabe
Successful paclitaxel-based chemotherapy for an alpha-fetoprotein-producing gastric cancer patient with multiple liver metastases.
World journal of surgical oncology 2007;5():79.
2007: Hiroki Takahashi; Hirozumi Sawai; Hitoshi Funahashi; Yoichi Matsuo; Akira Yasuda; Nobuo Ochi; Mikinori Sato; Yuji Okada; Hiromitsu Takeyama
Antiproteases in preventing the invasive potential of pancreatic cancer cells.
JOP : Journal of the pancreas 2007;8(4 Suppl):501-8.
2006: Moritsugu Tanaka; Hirozumi Sawai; Yuji Okada; Minoru Yamamoto; Hitoshi Funahashi; Tetsushi Hayakawa; Hiromitsu Takeyama; Tadao Manabe
Malignant solitary fibrous tumor originating from the peritoneum and review of the literature.
Medical science monitor : international medical journal of experimental and clinical research 2006;12(10):CS95-8.
2006: Hirozumi Sawai; Yuji Okada; Moritsugu Tanaka; Hitoshi Funahashi; Minoru Yamamoto; Hiromitsu Takeyama; Tadao Manabe
Combined gemcitabine and alpha-interferon therapy for pancreatic cancer: report of a case.
Digestive diseases and sciences 2006;51(7):1285-9.
2006: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Yoichi Matsuo; Hiroki Takahashi; Hiromitsu Takeyama; Tadao Manabe
Integrin-linked kinase activity is associated with interleukin-1 alpha-induced progressive behavior of pancreatic cancer and poor patient survival.
Oncogene 2006;25(23):3237-46.
2006: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Yoichi Matsuo; Minoru Yamamoto; Moritsugu Tanaka; Hiromitsu Takeyama; Tadao Manabe
Surgical treatment for relief of severe pain with chronic pancreatitis that is resistant to conservative treatment.
Hepato-gastroenterology 2006;53(69):438-41.
2006: Akira Yasuda; Hirozumi Sawai; Hiroki Takahashi; Nobuo Ochi; Yoichi Matsuo; Hitoshi Funahashi; Mikinori Sato; Yuji Okada; Hiromitsu Takeyama; Tadao Manabe
The stem cell factor/c-kit receptor pathway enhances proliferation and invasion of pancreatic cancer cells.
Molecular cancer 2006;5():46.
2006: Hiroki Takahashi; Hirozumi Sawai; Yoichi Matsuo; Hitoshi Funahashi; Mikinori Satoh; Yuji Okada; Hiroshi Inagaki; Hiromitsu Takeyama; Tadao Manabe
Reactive lymphoid hyperplasia of the liver in a patient with colon cancer: report of two cases.
BMC gastroenterology 2006;6():25.
2006: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Yoichi Matsuo; Hiroki Takahashi; Hiromitsu Takeyama; Tadao Manabe
Interleukin-1alpha enhances the aggressive behavior of pancreatic cancer cells by regulating the alpha6beta1-integrin and urokinase plasminogen activator receptor expression.
BMC cell biology 2006;7():8.
2006: Yoichi Matsuo; Hiroki Takahashi; Hirozumi Sawai; Yuji Okada; Tadao Manabe
[Molecular mechanism in pathogenesis in pancreatic neoplasms: NF-kappaB].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 1():44-7.
2005: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Yoichi Matsuo; Hiromitsu Takeyama; Tadao Manabe
Anaplastic carcinoma of the pancreas with squamous features: report of a case and immunohistochemical study.
Medical science monitor : international medical journal of experimental and clinical research 2005;11(11):CS65-8.
2005: Yoshinori Ito; Yuji Okada; Mikinori Sato; Hirozumi Sawai; Hitoshi Funahashi; Takayuki Murase; Tetsushi Hayakawa; Tadao Manabe
Expression of glial cell line-derived neurotrophic factor family members and their receptors in pancreatic cancers.
Surgery 2005;138(4):788-94.
2005: Hirozumi Sawai; Hitoshi Funahashi; Yuji Okada; Yoichi Matsuo; Masaki Sakamoto; Minoru Yamamoto; Hiromitsu Takeyama; Tadao Manabe
Interleukin-1alpha enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells.
Medical science monitor : international medical journal of experimental and clinical research 2005;11(10):BR343-50.
2005: Hitoshi Funahashi; Yuji Okada; Hirozumi Sawai; Minoru Yamamoto; Tetsushi Hayakawa; Moritsugu Tanaka; Hiromitsu Takeyama; Tadao Manabe
Serous cystadenoma of the pancreas has abnormal imaging characteristics: report of a case.
International surgery 2005;90(3):134-6.
2005: Hitoshi Funahashi; Yuji Okada; Hirozumi Sawai; Hiroki Takahashi; Yoichi Matsuo; Hiromitsu Takeyama; Tadao Manabe
The role of glial cell line-derived neurotrophic factor (GDNF) and integrins for invasion and metastasis in human pancreatic cancer cells.
Journal of surgical oncology 2005;91(1):77-83.
2005: Takeshi Hasegawa; Mikinori Sato; Masaaki Kurimoto; Hiroki Takahashi; Takashi Kawashima; Youichi Matsuo; Minoru Yamamoto; Hirozumi Sawai; Hitoshi Funahashi; Yuji Okada; Hiromitsu Takeyama; Tadao Manabe
Biological effect of irradiation on adhesion molecules in human colon cancer cells in vitro.
Anticancer research 2005;25(2A):875-9.
2005: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Yoichi Matsuo; Hiroki Takahashi; Hiromitsu Takeyama; Tadao Manabe
Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation.
Molecular cancer 2005;4():37.
2004: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Yoichi Matsuo; Moritsugu Tanaka; Tadao Manabe
Immunohistochemical analysis of molecular biological factors in intraductal papillary-mucinous tumors and mucinous cystic tumors of the pancreas.
Scandinavian journal of gastroenterology 2004;39(11):1159-65.
2004: Hitoshi Funahashi; Hirozumi Sawai; Yuji Okada; Masaki Sakamoto; Hiroki Takahashi; Youichi Matsuo; Takehiro Wakasugi; Minoru Yamamoto; Hiromitsu Takeyama; Tadao Manabe
[The QOL of the patient with advanced pancreatic carcinoma was changed for the better with combination therapy consisting of arterial chemotherapy and injection of interferon].
Gan to kagaku ryoho. Cancer & chemotherapy 2004;31(11):1832-4.
2004: Hiroki Takahashi; Hitoshi Funahashi; Hirozumi Sawai; Masaki Sakamoto; Yoichi Matsuo; Minoru Yamamoto; Yuji Okada; Tetsushi Hayakawa; Tadao Manabe
Glial cell line-derived neurotrophic factor enhances nuclear factor-kappaB activity and invasive potential in human pancreatic cancer cells.
Pancreas 2004;29(1):22-7.
2004: Yoichi Matsuo; Hirozumi Sawai; Hitoshi Funahashi; Hiroki Takahashi; Masaki Sakamoto; Minoru Yamamoto; Yuji Okada; Tetsushi Hayakawa; Tadao Manabe
Enhanced angiogenesis due to inflammatory cytokines from pancreatic cancer cell lines and relation to metastatic potential.
Pancreas 2004;28(3):344-52.
2004: Hirozumi Sawai; Yuji Okada; Hitoshi Funahashi; Yoichi Matsuo; Minoru Yamamoto; Tetsushi Hayakawa; Moritsugu Tanaka; Hiromitsu Takeyama; Tadao Manabe
Expression of integrins in tumour tissue of a patient with cancer of the Vater's ampulla complicated by pancreas divisum.
European journal of gastroenterology & hepatology 2004;16(4):421-4.
2004: Hirozumi Sawai; Yuji Okada; Moritsugu Tanaka; Hitoshi Funahashi; Tetsushi Hayakawa; Tadao Manabe
Expression of integrins in intraductal papillary-mucinous tumors of the pancreas as an indicator of malignancy.
Pancreas 2004;28(1):20-4.
2003: Hitoshi Funahashi; Hiromitsu Takeyama; Hirozumi Sawai; Akiyoshi Furuta; Mikinori Sato; Yuji Okada; Tetsushi Hayakawa; Moritsugu Tanaka; Tadao Manabe
Alteration of integrin expression by glial cell line-derived neurotrophic factor (GDNF) in human pancreatic cancer cells.
Pancreas 2003;27(2):190-6.
2003: Hirozumi Sawai; Moritsugu Tanaka; Hitoshi Funahashi; Minoru Yamamoto; Yuji Okada; Hiromitsu Takeyama; Tadao Manabe
Multiple primary cancers of the duodenum and sigmoid colon: report of two cases.
Digestive diseases and sciences 2003;48(7):1268-72.
2003: Hirozumi Sawai; Hitoshi Funahashi; Yoichi Matsuo; Minoru Yamamoto; Yuji Okada; Tetsushi Hayakawa; Tadao Manabe
Expression and prognostic roles of integrins and interleukin-1 receptor type I in patients with ductal adenocarcinoma of the pancreas.
Digestive diseases and sciences 2003;48(7):1241-50.
2003: Hirozumi Sawai; Moritsugu Tanaka; Hitoshi Funahashi; Minoru Yamamoto; Taku Miyamae; Yuji Okada; Hiromitsu Takeyama; Tadao Manabe
Tumor-forming pancreatitis diagnosed preoperatively as intraductal papillary-mucinous tumor: report of a case.
Pancreas 2003;26(2):207-10.
2003: Hirozumi Sawai; Hitoshi Funahashi; Minoru Yamamoto; Yuji Okada; Tetsushi Hayakawa; Moritsugu Tanaka; Hiromitsu Takeyama; Tadao Manabe
Interleukin-1alpha enhances integrin alpha(6)beta(1) expression and metastatic capability of human pancreatic cancer.
Oncology 2003;65(2):167-73.
2003: Hirozumi Sawai; Hiromitsu Takeyama; Minoru Yamamoto; Akiyoshi Furuta; Hitoshi Funahashi; Yuji Okada; Mikinori Sato; Moritsugu Tanaka; Tadao Manabe
Enhancement of integrins by interleukin-1alpha, and their relationship with metastatic and invasive behavior of human pancreatic ductal adenocarcinoma cells.
Journal of surgical oncology 2003;82(1):51-6.
2001: Hirozumi Sawai; Minoru Yamamoto; Yuji Okada; Mikinori Sato; Yoshimi Akamo; Hiromitsu Takeyama; Tadao Manabe
Alteration of integrins by interleukin-1alpha in human pancreatic cancer cells.
Pancreas 2001;23(4):399-405.
1999: Yuji Okada; Mariko Suchi; Hiromitsu Takeyama; ME Hodgson; T Kato; Tadao Manabe
Noncardiogenic pulmonary edema as the chief manifestation of a pheochromocytoma: a case report of MEN 2A with pedigree analysis of the RET proto-oncogene.
The Tohoku journal of experimental medicine 1999;188(2):177-87.
1999: Yuji Okada; Hiromitsu Takeyama; Mikinori Sato; M Morikawa; K Sobue; Kiyofumi Asai; T Tada; T Kato; Tadao Manabe
Experimental implication of celiac ganglionotropic invasion of pancreatic-cancer cells bearing c-ret proto-oncogene with reference to glial-cell-line-derived neurotrophic factor (GDNF).
International journal of cancer. Journal international du cancer 1999;81(1):67-73.