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Takashi Okai

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Satoshi Miyagami; Shingo Oishi; Akihiko Sekizawa; Walter Ventura; Junko Yotsumoto; Keiko Koide; Takashi Okai
Physiological changes in the pattern of placental gene expression early in the first trimester.
Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Masamitsu Nakamura; Shoko Hamada; Akihiko Sekizawa; Takashi Okai
Distribution of nuchal translucency thickness in Japanese fetuses.
Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Masamitsu Nakamura; Akihiko Sekizawa; Takashi Okai
Vasa previa is not infrequent.

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2013: Satoshi Miyagami; Shingo Oishi; Akihiko Sekizawa; Walter Ventura; Junko Yotsumoto; Keiko Koide; Takashi Okai
Physiological changes in the pattern of placental gene expression early in the first trimester.
Reproductive sciences (Thousand Oaks, Calif.) 2013;20(6):710-4.
2013: Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Masamitsu Nakamura; Shoko Hamada; Akihiko Sekizawa; Takashi Okai
Distribution of nuchal translucency thickness in Japanese fetuses.
The journal of obstetrics and gynaecology research 2013;39(4):766-9.
2012: Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Masamitsu Nakamura; Akihiko Sekizawa; Takashi Okai
Vasa previa is not infrequent.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2012;25(12):2795-6.
2012: Caroline E Fox; Takashi Okai; Samantha Pretlove; Akihiko Sekizawa; Ben C Chan; Mark D Kilby
Maternal cell-free messenger RNA in twin pregnancies: the effects of chorionicity and severe twin to twin transfusion syndrome (TTTS).
Acta obstetricia et gynecologica Scandinavica 2012;91(10):1206-11.
2012: Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Masamitsu Nakamura; Ayumi Okuyama; Akihiko Sekizawa; Shoko Hamada; Takashi Okai
Gestational weight loss has adverse effects on placental development.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2012;25(10):1909-12.
2012: Kiyotake Ichizuka; Ryu Matsuoka; M Nakamura; Takashi Okai; Akihiko Sekizawa; Junichi Hasegawa; S Umemura
High-intensity focused ultrasound treatment for twin reversed arterial perfusion sequence.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2012;40(4):476-8.
2012: Masamitsu Nakamura; Akihiko Sekizawa; Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuaka; Takashi Mimura; Takashi Okai
Amount of hemorrhage during vaginal delivery correlates with length from placental edge to external os in cases with low-lying placenta whose length between placental edge and internal os was 1-2 cm.
The journal of obstetrics and gynaecology research 2012;38(8):1041-5.
2012: Azusa Shinjo; Mayumi Tokunaka; Ryu Matsuoka; Tomohiro Oba; Hajime Ota; Katsufumi Otsuki; Maki Sawada; Takashi Okai
Retrospective cohort study: a comparison of two different management strategies in patients with preterm premature rupture of membranes.
Archives of gynecology and obstetrics 2012;286(2):337-45.
2012: Yasushi Sasaki; Jun Takahashi; Koichi Ogawa; Takashi Okai
Complete hydatidiform mole coexisting with a normal fetus delivered at 33 weeks of gestation and involving maternal lung metastasis: a case report.
The Journal of reproductive medicine 2012;57(7-8):301-4.
2012: Junko Yotsumoto; Yuditiya Purwosunu; Akihiko Sekizawa; Kiyotake Ichizuka; Hiroshi Kawame; Keiko Koide; Ryu Matsuoka; Takashi Okai
Attitudes toward non-invasive prenatal diagnosis among pregnant women and health professionals in Japan.
Prenatal diagnosis 2012;32(7):674-9.
2012: Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Masamitsu Nakamura; Shoko Hamada; Akihiko Sekizawa; Takashi Okai
Prediction of hemorrhage in placenta previa.
Taiwanese journal of obstetrics & gynecology 2012;51(1):3-6.
2011: Shoko Hamada; Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Masamitsu Nakamura; Akihiko Sekizawa; Takashi Okai
Ultrasonographic findings of placenta lacunae and a lack of a clear zone in cases with placenta previa and normal placenta.
Prenatal diagnosis 2011;31(11):1062-5.
2011: Junichi Hasegawa; Kiyotake Ichizuka; Otsuki Katsufumi; Ryu Matsuoka; Masamitsu Nakamura; Kaori Arakawa; Akihiko Sekizawa; Takashi Okai
Analysis of placental weight centiles is useful to estimate cause of fetal growth restriction.
The journal of obstetrics and gynaecology research 2011;37(11):1658-65.
2011: J Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; M Nakamura; Antonio Farina; Akihiko Sekizawa; Takashi Okai
Location of the placenta or the umbilical cord insertion site in the lowest uterine segment is associated with low maternal blood pressure.
BJOG : an international journal of obstetrics and gynaecology 2011;118(12):1464-9.
2011: Junichi Hasegawa; Kiyotake Ichizuka; Shinji Iwasaki; Ryu Matsuoka; Akihiko Sekizawa; Takashi Okai
Velamentous cord insertion caused by oblique implantation after in vitro fertilization and embryo transfer.
The journal of obstetrics and gynaecology research 2011;37(11):1698-701.
2011: Junichi Hasegawa; Miwa Higashi; Kiyotake Ichizuka; Ryu Matsuoka; Takashi Mimura; Masamitsu Nakamura; Akihiko Sekizawa; Shoko Takahashi; Takashi Okai
Can ultrasonography of the placenta previa predict antenatal bleeding?
Journal of clinical ultrasound : JCU 2011;39(8):458-62.
2011: Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Masamitsu Nakamura; Akihiko Sekizawa; Takashi Okai
Prediction of risk for vasa previa at 9-13 weeks' gestation.
The journal of obstetrics and gynaecology research 2011;37(10):1346-51.
2011: Takashi Mimura; Masamitsu Nakamura; Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Akihiko Sekizawa; Takashi Okai
Correlation between the cervical length and the amount of bleeding during cesarean section in placenta previa.
The journal of obstetrics and gynaecology research 2011;37(7):830-5.
2011: Antonio Farina; Cinzia Zucchini; Paola De Sanctis; Danila Morano; Akihiko Sekizawa; Yuditiya Purwosunu; Takashi Okai; Nicola Rizzo
Gene expression in chorionic villous samples at 11 weeks of gestation in women who develop pre-eclampsia later in pregnancy: implications for screening.
Prenatal diagnosis 2011;31(2):181-5.
2011: Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; Takashi Mimura; Masamitsu Nakamura; Shoko Hamada; Akihiko Sekizawa; Takashi Okai
Localization of the embryo in the lower part of the gestational sac at 6-7 weeks' gestation is associated with placenta previa.
Fetal diagnosis and therapy 2011;30(3):203-6.
2010: Antonio Farina; Cinzia Zucchini; Akihiko Sekizawa; Yuditiya Purwosunu; Paola de Sanctis; Giuseppe Santarsiero; Nicola Rizzo; Danila Morano; Takashi Okai
Performance of messenger RNAs circulating in maternal blood in the prediction of preeclampsia at 10-14 weeks.
American journal of obstetrics and gynecology 2010;203(6):575.e1-7.
2010: Junichi Hasegawa; Antonio Farina; Masamitsu Nakamura; Ryu Matsuoka; Kiyotake Ichizuka; Akihiko Sekizawa; Takashi Okai
Analysis of the ultrasonographic findings predictive of vasa previa.
Prenatal diagnosis 2010;30(12-13):1121-5.
2010: Takashi Okai; Tomoaki Ikeda; Tatsuhiko Kawarabayashi; Shiro Kozuma; Junichi Sugawara; Hiroshi Chisaka; Satoshi Yoneda; Ryu Matsuoka; Hitoo Nakano; Kunihiro Okamura; Shigeru Saito
Intrapartum management guidelines based on fetal heart rate pattern classification.
The journal of obstetrics and gynaecology research 2010;36(5):925-8.
2010: Junichi Hasegawa; T Mimura; T Morimoto; Ryu Matsuoka; Kiyotake Ichizuka; Akihiko Sekizawa; Takashi Okai
Detection of umbilical venous constriction by Doppler flow measurement at midgestation.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2010;36(2):196-201.
2010: Akihiko Sekizawa; Yuditiya Purwosunu; Antonio Farina; H Shimizu; M Nakamura; Noroyono Wibowo; Nicola Rizzo; Takashi Okai
Prediction of pre-eclampsia by an analysis of placenta-derived cellular mRNA in the blood of pregnant women at 15-20 weeks of gestation.
BJOG : an international journal of obstetrics and gynaecology 2010;117(5):557-64.
2010: Tsuyoshi Okuda; Akihiko Sekizawa; Yuditiya Purwosunu; Masaaki Nagatsuka; Miki Morioka; Masaki Hayashi; Takashi Okai
Genetics of endometrial cancers.
Obstetrics and gynecology international 2010;2010():984013.
2010: Junichi Hasegawa; Masamitsu Nakamura; Ryu Matsuoka; Takashi Mimura; Kiyotake Ichizuka; Akihiko Sekizawa; Takashi Okai
Evaluation of placental function using near infrared spectroscopy during fetal growth restriction.
Journal of perinatal medicine 2010;38(1):29-32.
2009: Hanako Shimizu; Akihiko Sekizawa; Yuditiya Purwosunu; Masamitsu Nakamura; Antonio Farina; Nicola Rizzo; Takashi Okai
PP13 mRNA expression in the cellular component of maternal blood as a marker for preeclampsia.
Prenatal diagnosis 2009;29(13):1231-6.
2009: Yuditiya Purwosunu; Akihiko Sekizawa; Shiho Yoshimura; Antonio Farina; Noroyono Wibowo; Masamitsu Nakamura; Hanako Shimizu; Takashi Okai
Expression of angiogenesis-related genes in the cellular component of the blood of preeclamptic women.
Reproductive sciences (Thousand Oaks, Calif.) 2009;16(9):857-64.
2009: Keiko Koide; Akihiko Sekizawa; Masamitsu Nakamura; Ryu Matsuoka; Takashi Okai
Hypovolemic shock due to massive edema of a pedunculated uterine myoma after delivery.
The journal of obstetrics and gynaecology research 2009;35(4):794-6.
2009: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; T Mimura; Akihiko Sekizawa; Antonio Farina; Takashi Okai
Predisposing factors for massive hemorrhage during Cesarean section in patients with placenta previa.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2009;34(1):80-4.
2009: Masamitsu Nakamura; Akihiko Sekizawa; Yuditiya Purwosunu; Shiho Okazaki; Antonio Farina; Noroyono Wibowo; Hanako Shimizu; Takashi Okai
Cellular mRNA expressions of anti-oxidant factors in the blood of preeclamptic women.
Prenatal diagnosis 2009;29(7):691-6.
2009: Yuditiya Purwosunu; Akihiko Sekizawa; Shiho Okazaki; Antonio Farina; Noroyono Wibowo; Masamitsu Nakamura; Nicola Rizzo; Hiroshi Saito; Takashi Okai
Prediction of preeclampsia by analysis of cell-free messenger RNA in maternal plasma.
American journal of obstetrics and gynecology 2009;200(4):386.e1-7.
2009: Akihiko Sekizawa; Yuditiya Purwosunu; Shiho Yoshimura; Masamitsu Nakamura; Hanako Shimizu; Takashi Okai; Nicola Rizzo; Antonio Farina
PP13 mRNA expression in trophoblasts from preeclamptic placentas.
Reproductive sciences (Thousand Oaks, Calif.) 2009;16(4):408-13.
2009: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Akihiko Sekizawa; Takashi Okai
Ultrasound diagnosis and management of umbilical cord abnormalities.
Taiwanese journal of obstetrics & gynecology 2009;48(1):23-7.
2009: Keiichiro Yoneyama; Aiko Kimura; Mari Kogo; Yuji Kiuchi; Taro Morimoto; Takashi Okai
Clinical predictive factors for preterm birth in women with threatened preterm labour or preterm premature ruptured membranes?
The Australian & New Zealand journal of obstetrics & gynaecology 2009;49(1):16-21.
2009: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Mihoko Kotani; Masamitsu Nakamura; Takao Mikoshiba; Akihiko Sekizawa; Takashi Okai
Atypical variable deceleration in the first stage of labor is a characteristic fetal heart-rate pattern for velamentous cord insertion and hypercoiled cord.
The journal of obstetrics and gynaecology research 2009;35(1):35-9.
2009: Minoru Kurita; Junichi Hasegawa; Takao Mikoshiba; Yuditiya Purwosunu; Ryu Matsuoka; Kiyotake Ichizuka; Akihiko Sekizawa; Takashi Okai
Ultrasound evaluation of the amount of Wharton's jelly and the umbilical coiling index.
Fetal diagnosis and therapy 2009;26(2):85-9.
2009: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Akihiko Sekizawa; Takashi Okai
Umbilical cord insertion site in early gestation and development of placenta.
Journal of perinatal medicine 2009;37(5):481-5.
2009: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Masamitsu Nakamura; Akihiko Sekizawa; Takashi Okai
Do fetal heart rate deceleration patterns during labor differ between various umbilical cord abnormalities?
Journal of perinatal medicine 2009;37(3):276-80.
2008: Ken Nakayama; Katsufumi Otsuki; Kyoko Yakuwa; Akitoshi Hasegawa; Maki Sawada; Kaori Mitsukawa; Hiroshi Chiba; Masaaki Nagatsuka; Takashi Okai
Recombinant human lactoferrin inhibits matrix metalloproteinase (MMP-2, MMP-3, and MMP-9) activity in a rabbit preterm delivery model.
The journal of obstetrics and gynaecology research 2008;34(6):931-4.
2008: Antonio Farina; Akihiko Sekizawa; Paola De Sanctis; Yuditiya Purwosunu; Takashi Okai; Dong Hyun Cha; Jin Hee Kang; Claudia Vicenzi; Annalisa Tempesta; Noroyono Wibowo; Luisella Valvassori; Nicola Rizzo
Gene expression in chorionic villous samples at 11 weeks' gestation from women destined to develop preeclampsia.
Prenatal diagnosis 2008;28(10):956-61.
2008: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Mihoko Kotani; Azumi Ohmori; Masamitsu Nakamura; Akihiko Sekizawa; Takashi Okai
Intrapartum fetal heart rate pattern in oligohydramnios.
Fetal diagnosis and therapy 2008;24(3):267-70.
2008: Yuditiya Purwosunu; Akihiko Sekizawa; Takashi Okai
Detection and quantification of fetal DNA in maternal plasma by using LightCycler technology.
Methods in molecular biology (Clifton, N.J.) 2008;444():231-8.
2008: Yuditiya Purwosunu; Akihiko Sekizawa; Antonio Farina; Noroyono Wibowo; Keiko Koide; Shiho Okazaki; Masamitsu Nakamura; Takashi Okai
Evaluation of physiological alterations of the placenta through analysis of cell-free messenger ribonucleic acid concentrations of angiogenic factors.
American journal of obstetrics and gynecology 2008;198(1):124.e1-7.
2007: Akihiko Sekizawa; Yuditiya Purwosunu; Ryu Matsuoka; Keiko Koide; Shiho Okazaki; Antonio Farina; Hiroshi Saito; Takashi Okai
Recent advances in non-invasive prenatal DNA diagnosis through analysis of maternal blood.
The journal of obstetrics and gynaecology research 2007;33(6):747-64.
2007: Shiho Okazaki; Akihiko Sekizawa; Yuditiya Purwosunu; Antonio Farina; Noroyono Wibowo; Takashi Okai
Placenta-derived, cellular messenger RNA expression in the maternal blood of preeclamptic women.
Obstetrics and gynecology 2007;110(5):1130-6.
2007: Junichi Hasegawa; Atsushi Yanaihara; Shinji Iwasaki; Kaori Mitsukawa; Momoko Negishi; Takashi Okai
Reduction of connexin 43 in human cumulus cells yields good embryo competence during ICSI.
Journal of assisted reproduction and genetics 2007;24(10):463-6.
2007: Akihiko Sekizawa; Yuditiya Purwosunu; Antonio Farina; Takashi Okai; Haruo Takabayashi; Mikiko Kita; Hirofumi Yura; Michihiro Kitagawa
Development of noninvasive fetal DNA diagnosis from nucleated erythrocytes circulating in maternal blood.
Prenatal diagnosis 2007;27(9):846-8.
2007: Yuditiya Purwosunu; Akihiko Sekizawa; Antonio Farina; Noroyono Wibowo; Shiho Okazaki; Masamitsu Nakamura; Osamu Samura; Naoya Fujito; Takashi Okai
Cell-free mRNA concentrations of CRH, PLAC1, and selectin-P are increased in the plasma of pregnant women with preeclampsia.
Prenatal diagnosis 2007;27(8):772-7.
2007: Tomoko Akahane; Akihiko Sekizawa; Yuditiya Purwosunu; Masaaki Nagatsuka; Takashi Okai
The role of p53 mutation in the carcinomas arising from endometriosis.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2007;26(3):345-51.
2007: Kiyotake Ichizuka; S Ando; Mitsuyoshi Ichihara; T Ishikawa; N Uchiyama; Kazuaki Sasaki; Shin-ichiro Umemura; Ryu Matsuoka; Akihiko Sekizawa; Takashi Okai; Tomoko Akabane; Miki Kushima
Application of high-intensity focused ultrasound for umbilical artery occlusion in a rabbit model.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2007;30(1):47-51.
2007: Kyoko Yakuwa; Katsufumi Otsuki; K Nakayama; Akitoshi Hasegawa; Maki Sawada; Kaori Mitsukawa; Hiroshi Chiba; Masaaki Nagatsuka; Takashi Okai
Recombinant human lactoferrin has a potential to suppresses uterine cervical ripening in preterm delivery in animal model.
Archives of gynecology and obstetrics 2007;275(5):331-4.
2007: Yuditiya Purwosunu; Akihiko Sekizawa; Keiko Koide; Antonio Farina; Noroyono Wibowo; Gulardi Hanifa Wiknjosastro; Shiho Okazaki; Hiroshi Chiba; Takashi Okai
Cell-free mRNA concentrations of plasminogen activator inhibitor-1 and tissue-type plasminogen activator are increased in the plasma of pregnant women with preeclampsia.
Clinical chemistry 2007;53(3):399-404.
2007: Mitsuyoshi Ichihara; Kazuaki Sasaki; Shin-ichiro Umemura; Miki Kushima; Takashi Okai
Blood flow occlusion via ultrasound image-guided high-intensity focused ultrasound and its effect on tissue perfusion.
Ultrasound in medicine & biology 2007;33(3):452-9.
2007: Atsushi Yanaihara; Kaori Mitsukawa; Shinji Iwasaki; Katsufumi Otsuki; Toshihiro Kawamura; Takashi Okai
High concentrations of lactoferrin in the follicular fluid correlate with embryo quality during in vitro fertilization cycles.
Fertility and sterility 2007;87(2):279-82.
2007: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Hiroshi Fujikawa; Akihiko Sekizawa; Takashi Okai
Umbilical cord insertion to the lower uterine segment is a risk factor for vasa previa.
Fetal diagnosis and therapy 2007;22(5):358-60.
2006: Antonio Farina; Akihiko Sekizawa; Yuditiya Purwosunu; Nicola Rizzo; Irina Banzola; Manuela Concu; Danila Morano; Federica Giommi; Maurizio Bevini; Mohamad Mabrook; Paolo Carinci; Takashi Okai
Quantitative distribution of a panel of circulating mRNA in preeclampsia versus controls.
Prenatal diagnosis 2006;26(12):1115-20.
2006: S Okazaki; Akihiko Sekizawa; Yuditiya Purwosunu; M Iwasaki; Antonio Farina; Takashi Okai
Measurement of mRNA of trophoblast-specific genes in cellular and plasma components of maternal blood.
Journal of medical genetics 2006;43(9):e47.
2006: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; K Otsuki; Akihiko Sekizawa; Antonio Farina; Takashi Okai
Cord insertion into the lower third of the uterus in the first trimester is associated with placental and umbilical cord abnormalities.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;28(2):183-6.
2006: Yuditiya Purwosunu; Akihiko Sekizawa; Antonio Farina; Takashi Okai; Haruo Takabayashi; Peng Wen; Hirofumi Yura; Michihiro Kitagawa
Enrichment of NRBC in maternal blood: a more feasible method for noninvasive prenatal diagnosis.
Prenatal diagnosis 2006;26(6):545-7.
2006: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Akihiko Sekizawa; Antonio Farina; Takashi Okai
Velamentous cord insertion into the lower third of the uterus is associated with intrapartum fetal heart rate abnormalities.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;27(4):425-9.
2006: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Akihiko Sekizawa; Takashi Okai
Velamentous cord insertion: significance of prenatal detection to predict perinatal complications.
Taiwanese journal of obstetrics & gynecology 2006;45(1):21-5.
2006: Yuditiya Purwosunu; Akihiko Sekizawa; Keiko Koide; Shiho Okazaki; Antonio Farina; Takashi Okai
Clinical potential for noninvasive prenatal diagnosis through detection of fetal cells in maternal blood.
Taiwanese journal of obstetrics & gynecology 2006;45(1):10-20.
2006: Atsushi Yanaihara; Shinji Iwasaki; Momoko Negishi; Takashi Okai
Sperm retention site and its influence on cleavage rate and early development following intracytoplasmic sperm injection.
Journal of assisted reproduction and genetics 2006;23(2):63-7.
2006: Maki Sawada; Katsufumi Otsuki; Kaori Mitsukawa; Kyoko Yakuwa; Masaaki Nagatsuka; Takashi Okai
Cervical inflammatory cytokines and other markers in the cervical mucus of pregnant women with lower genital tract infection.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2006;92(2):117-21.
2005: Tomoko Akahane; Akihiko Sekizawa; Tsuyoshi Okuda; Miki Kushima; Hiroshi Saito; Takashi Okai
Disappearance of steroid hormone dependency during malignant transformation of ovarian clear cell cancer.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2005;24(4):369-76.
2005: Atsushi Yanaihara; Yukiko Otsuka; Shinji Iwasaki; Takashi Okai; Takumi Yanaihara
Strong expression of steroid sulfatase in human cumulus cells in patients with endometriosis.
Fertility and sterility 2005;84(2):464-7.
2005: Junichi Hasegawa; Atsushi Yanaihara; Shinji Iwasaki; Yukiko Otsuka; Momoko Negishi; Tomoko Akahane; Takashi Okai
Reduction of progesterone receptor expression in human cumulus cells at the time of oocyte collection during IVF is associated with good embryo quality.
Human reproduction (Oxford, England) 2005;20(8):2194-200.
2005: Keiko Koide; Akihiko Sekizawa; Mariko Iwasaki; Ryu Matsuoka; Susumu Honma; Antonio Farina; Hiroshi Saito; Takashi Okai
Fragmentation of cell-free fetal DNA in plasma and urine of pregnant women.
Prenatal diagnosis 2005;25(7):604-7.
2005: Junichi Hasegawa; Ryu Matsuoka; Kiyotake Ichizuka; Akihiko Sekizawa; Antonio Farina; Takashi Okai
Velamentous cord insertion and atypical variable decelerations with no accelerations.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2005;90(1):26-30.
2005: Akitoshi Hasegawa; Katsufumi Otsuki; Yasushi Sasaki; Maki Sawada; Kaori Mitsukawa; Hiroshi Chiba; Masaaki Nagatsuka; Takashi Okai; Atsuko Kato
Preventive effect of recombinant human lactoferrin in a rabbit preterm delivery model.
American journal of obstetrics and gynecology 2005;192(4):1038-43.
2005: Atsushi Yanaihara; Yukiko Otsuka; Shinji Iwasaki; Tadateru Aida; Tetsuhiko Tachikawa; Taro Irie; Takashi Okai
Differences in gene expression in the proliferative human endometrium.
Fertility and sterility 2005;83 Suppl 1():1206-15.
2005: Kiyotake Ichizuka; Ryu Matsuoka; Junichi Hasegawa; Nahoko Shirato; Masatoshi Jimbo; Katsufumi Otsuki; Akihiko Sekizawa; Antonio Farina; Takashi Okai
The Tei index for evaluation of fetal myocardial performance in sick fetuses.
Early human development 2005;81(3):273-9.
2005: Junichi Hasegawa; Kiyotake Ichizuka; Ryu Matsuoka; K Otsuki; Akihiko Sekizawa; Takashi Okai
Limitations of conservative treatment for repeat Cesarean scar pregnancy.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2005;25(3):310-1.
2005: Katsufumi Otsuki; Kyoko Yakuwa; Maki Sawada; Akitoshi Hasegawa; Yasushi Sasaki; Kaori Mitsukawa; Hiroshi Chiba; Masaaki Nagatsuka; Hiroshi Saito; Takashi Okai
Recombinant human lactoferrin has preventive effects on lipopolysaccharide-induced preterm delivery and production of inflammatory cytokines in mice.
Journal of perinatal medicine 2005;33(4):320-3.
2004: Yasushi Sasaki; Katsufumi Otsuki; Akitoshi Hasegawa; Maki Sawada; Hiroshi Chiba; Momoko Negishi; Masaaki Nagatsuka; Takashi Okai
Preventive effect of recombinant human lactoferrin on lipopolysaccharide-induced preterm delivery in mice.
Acta obstetricia et gynecologica Scandinavica 2004;83(11):1035-8.
2004: Atsushi Yanaihara; Yukiko Otsuka; Shinji Iwasaki; Keiko Koide; Tadateru Aida; Takashi Okai
Comparison in gene expression of secretory human endometrium using laser microdissection.
Reproductive biology and endocrinology : RB&E 2004;2():66.
2004: Junko Otsuka; Tsuyoshi Okuda; Akihiko Sekizawa; Satoshi Amemiya; Hiroshi Saito; Takashi Okai; Miki Kushima; Tetsuhiko Tachikawa
K-ras mutation may promote carcinogenesis of endometriosis leading to ovarian clear cell carcinoma.
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan 2004;37(3):188-92.
2004: Akihiko Sekizawa; Antonio Farina; Keiko Koide; Mariko Iwasaki; Susumu Honma; Kiyotake Ichizuka; Hiroshi Saito; Takashi Okai
beta-globin DNA in maternal plasma as a molecular marker of pre-eclampsia.
Prenatal diagnosis 2004;24(9):697-700.
2004: Antonio Farina; Akihiko Sekizawa; Mariko Iwasaki; Ryu Matsuoka; Kiyotake Ichizuka; Takashi Okai
Total cell-free DNA (beta-globin gene) distribution in maternal plasma at the second trimester: a new prospective for preeclampsia screening.
Prenatal diagnosis 2004;24(9):722-6.
2004: Satoshi Amemiya; Akihiko Sekizawa; Junko Otsuka; Tetsuhiko Tachikawa; Hiroshi Saito; Takashi Okai
Malignant transformation of endometriosis and genetic alterations of K-ras and microsatellite instability.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2004;86(3):371-6.
2004: Akihiko Sekizawa; Satoshi Amemiya; Junko Otsuka; Hiroshi Saito; Antonio Farina; Takashi Okai; Tetsuhiko Tachikawa
Malignant transformation of endometriosis: application of laser microdissection for analysis of genetic alterations according to pathological changes.
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan 2004;37(2):97-100.
2004: Junko Otsuka; Tsuyoshi Okuda; Akihiko Sekizawa; Satoshi Amemiya; Hiroshi Saito; Takashi Okai; Miki Kushima
Detection of p53 mutations in the plasma DNA of patients with ovarian cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2004;14(3):459-64.
2004: Antonio Farina; Akihiko Sekizawa; Nicola Rizzo; Manuela Concu; Irina Banzola; Paolo Carinci; Giuliana Simonazzi; Takashi Okai
Cell-free fetal DNA (SRY locus) concentration in maternal plasma is directly correlated to the time elapsed from the onset of preeclampsia to the collection of blood.
Prenatal diagnosis 2004;24(4):293-7.
2004: Antonio Farina; Akihiko Sekizawa; Yumi Sugito; Mariko Iwasaki; Masatoshi Jimbo; Hiroshi Saito; Takashi Okai
Fetal DNA in maternal plasma as a screening variable for preeclampsia. A preliminary nonparametric analysis of detection rate in low-risk nonsymptomatic patients.
Prenatal diagnosis 2004;24(2):83-6.
2004: Akihiko Sekizawa; Antonio Farina; Yumi Sugito; Ryu Matsuoka; Mariko Iwasaki; Hiroshi Saito; Takashi Okai
Proteinuria and hypertension are independent factors affecting fetal DNA values: a retrospective analysis of affected and unaffected patients.
Clinical chemistry 2004;50(1):221-4.
2003: Tetsuya Ishikawa; Takashi Okai; Kazuaki Sasaki; Shin-ichiro Umemura; Rei Fujiwara; Miki Kushima; Mitsuyoshi Ichihara; Kiyotake Ichizuka
Functional and histological changes in rat femoral arteries by HIFU exposure.
Ultrasound in medicine & biology 2003;29(10):1471-7.
2003: Yumi Sugito; Akihiko Sekizawa; Antonio Farina; Yasuo Yukimoto; Hiroshi Saito; Mariko Iwasaki; Nicola Rizzo; Takashi Okai
Relationship between severity of hyperemesis gravidarum and fetal DNA concentration in maternal plasma.
Clinical chemistry 2003;49(10):1667-9.
2003: Masatoshi Jimbo; Akihiko Sekizawa; Yumi Sugito; Ryu Matsuoka; Kiyotake Ichizuka; Hiroshi Saito; Takashi Okai
Placenta increta: Postpartum monitoring of plasma cell-free fetal DNA.
Clinical chemistry 2003;49(9):1540-1.
2003: Akihiko Sekizawa; Kaori Yokokawa; Yumi Sugito; Mariko Iwasaki; Yasuo Yukimoto; Kiyotake Ichizuka; Hiroshi Saito; Takashi Okai
Evaluation of bidirectional transfer of plasma DNA through placenta.
Human genetics 2003;113(4):307-10.
2003: Tsuyoshi Okuda; Junko Otsuka; Akihiko Sekizawa; Hiroshi Saito; Reiko Makino; Miki Kushima; Antonio Farina; Yuzuru Kuwano; Takashi Okai
p53 mutations and overexpression affect prognosis of ovarian endometrioid cancer but not clear cell cancer.
Gynecologic oncology 2003;88(3):318-25.
2003: Akihiko Sekizawa; Masatoshi Jimbo; Hiroshi Saito; Mariko Iwasaki; Ryu Matsuoka; Takashi Okai; Antonio Farina
Cell-free fetal DNA in the plasma of pregnant women with severe fetal growth restriction.
American journal of obstetrics and gynecology 2003;188(2):480-4.
2002: Tetsuro Kondo; Akihiko Sekizawa; Hiroshi Saito; Masatoshi Jimbo; Yumi Sugito; Takashi Okai
Fate of fetal nucleated erythrocytes circulating in maternal blood: apoptosis is induced by maternal oxygen concentration.
Clinical chemistry 2002;48(9):1618-20.
2002: Susumu Honma; Kazuhisa Shimodaira; Yukiko Shimizu; Naoko Tsuchiya; Hiroshi Saito; Takumi Yanaihara; Takashi Okai
The influence of inflammatory cytokines on estrogen production and cell proliferation in human breast cancer cells.
Endocrine journal 2002;49(3):371-7.
2002: Ryu Matsuoka; Atsushi Yanaihara; Hiroshi Saito; Yoshiaki Furusawa; Yoshiro Toma; Yukiko Shimizu; Takumi Yanaihara; Takashi Okai
Regulation of estrogen activity in human endometrium: effect of IL-1beta on steroid sulfatase activity in human endometrial stromal cells.
Steroids 2002;67(7):655-9.
2002: Akihiko Sekizawa; Masatoshi Jimbo; Hiroshi Saito; Mariko Iwasaki; Yumi Sugito; Yasuo Yukimoto; Junko Otsuka; Takashi Okai
Increased cell-free fetal DNA in plasma of two women with invasive placenta.
Clinical chemistry 2002;48(2):353-4.
2001: Akihiko Sekizawa; Yumi Sugito; Mariko Iwasaki; A Watanabe; Masatoshi Jimbo; S Hoshi; Hiroshi Saito; Takashi Okai
Cell-free fetal DNA is increased in plasma of women with hyperemesis gravidarum.
Clinical chemistry 2001;47(12):2164-5.
2001: Akihiko Sekizawa; T Kondo; Mariko Iwasaki; A Watanabe; Masatoshi Jimbo; Hiroshi Saito; Takashi Okai
Accuracy of fetal gender determination by analysis of DNA in maternal plasma.
Clinical chemistry 2001;47(10):1856-8.
2001: Tsuyoshi Okuda; Hiroshi Saito; Akihiko Sekizawa; Yukiko Shimizu; T Akamatsu; Miki Kushima; Takumi Yanaihara; Takashi Okai; Antonio Farina
Steroid sulfatase expression in ovarian clear cell adenocarcinoma: immunohistochemical study.
Gynecologic oncology 2001;82(3):427-34.
2001: S Hoshi; T Morimoto; Hiroshi Saito; Kiyotake Ichizuka; Ryu Matsuoka; Atsushi Yanaihara; M Suzuki; Takumi Yanaihara; Takashi Okai
PTHrP and PTH/PTHrP receptor expressions in human endometrium.
Endocrine journal 2001;48(2):219-25.
2001: Atsushi Yanaihara; Takumi Yanaihara; Yoshiro Toma; Yukiko Shimizu; Hiroshi Saito; Takashi Okai; T Higashiyama; Yoshio Osawa
Localization and expression of steroid sulfatase in human fallopian tubes.
Steroids 2001;66(2):87-91.