FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Koichi Okamoto

Research Profile

Procedures

Immunohistochemistry

Disorders

Anatomy

Living Beings

Concepts & Ideas

Magnetic Resonance Imaging

Chemicals & Drugs

Physiology

Mutation

Co-author Network

Publications

TOP 3
Masaki Ikeda; Satoko Kakuda; Hiroo Kasahara; Kouki Makioka; Yoichi Nakazato; Masakuni Amari; Motonobu Arai; Yukio Fujita; Natsumi Furuta; Kimitoshi Hirayanagi; Eriko Takai; Masamitsu Takatama; Setsuki Tsukagoshi; Koichi Okamoto
Encephalopathy with amyloid angiopathy and numerous amyloid plaques with low levels of CSF Aβ1-40/Aβ1-42.
Mitsuko Ushikubo; Koichi Okamoto
Circumstances surrounding death and nursing difficulties with end-of-life care for individuals with ALS in central Japan.
Yuji Mizuno; Yukio Fujita; Masamitsu Takatama; Koichi Okamoto
Comparison of phosphorylated TDP-43-positive inclusions in oculomotor neurons in patients with non-ALS and ALS disorders.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Koichi Okamoto (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Masaki Ikeda; Satoko Kakuda; Hiroo Kasahara; Kouki Makioka; Yoichi Nakazato; Masakuni Amari; Motonobu Arai; Yukio Fujita; Natsumi Furuta; Kimitoshi Hirayanagi; Eriko Takai; Masamitsu Takatama; Setsuki Tsukagoshi; Koichi Okamoto
Encephalopathy with amyloid angiopathy and numerous amyloid plaques with low levels of CSF Aβ1-40/Aβ1-42.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2012;19(4):186-90.
2012: Mitsuko Ushikubo; Koichi Okamoto
Circumstances surrounding death and nursing difficulties with end-of-life care for individuals with ALS in central Japan.
International journal of palliative nursing 2012;18(11):554-60.
2012: Yuji Mizuno; Yukio Fujita; Masamitsu Takatama; Koichi Okamoto
Comparison of phosphorylated TDP-43-positive inclusions in oculomotor neurons in patients with non-ALS and ALS disorders.
Journal of the neurological sciences 2012;315(1-2):20-5.
2012: Kouki Makioka; Yoichi Nakazato; Masamitsu Takatama; Tsuneo Yamazaki; Koichi Okamoto
Activation and alteration of lysosomes in multiple system atrophy.
Neuroreport 2012;23(5):270-6.
2012: Natsumi Furuta; Masaki Ikeda; Yukio Fujita; Yuichi Tashiro; Koichi Okamoto
[A case of POEMS syndrome associated with Waldenström's macroglobulinemia and treated with lenalidomide].
Rinshō shinkeigaku = Clinical neurology 2012;52(3):186-9.
2011: Koichi Okamoto
[Recent pathological classification of frontotemporal lobar degeneration].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 10(Pt 2):375-8.
2011: Tenshi Osawa; Masamitsu Takatama; Yukio Fujita; Yuji Mizuno; Yoichi Nakazato; Koichi Okamoto
Optineurin in neurodegenerative diseases.
Neuropathology : official journal of the Japanese Society of Neuropathology 2011;31(6):569-74.
2011: Yukio Fujita; Koichi Okamoto
[FUS/TLS in frontotemporal lobar degeneration].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 8():88-92.
2011: Shintaro Hayashi; Koichi Okamoto
[Leber's hereditary optic neuropathy after head trauma: a case report].
Rinshō shinkeigaku = Clinical neurology 2011;51(10):781-3.
2011: Koichi Okamoto
[108th Scientific Meeting of the Japanese Society of Internal Medicine: symposium: 1. Progress in dementia research--dementia disorders and protein; (5) TDP-43].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(9):2489-94.
2011: Yukio Fujita; Sayaka Fujita; Masamitsu Takatama; Masaki Ikeda; Koichi Okamoto
Numerous FUS-positive inclusions in an elderly woman with motor neuron disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2011;31(2):170-6.
2011: Yuji Mizuno; Yukio Fujita; Masamitsu Takatama; Koichi Okamoto
Peripherin partially localizes in Bunina bodies in amyotrophic lateral sclerosis.
Journal of the neurological sciences 2011;302(1-2):14-8.
2011: Yukio Fujita; Kazuhiko Watabe; Ken Ikeda; Yuji Mizuno; Koichi Okamoto
Morphological changes of Golgi apparatus in adult rats after facial nerve injuries.
Neuropathology : official journal of the Japanese Society of Neuropathology 2011;31(1):42-7.
2010: Kouki Makioka; Tsuneo Yamazaki; Yukio Fujita; Masamitsu Takatama; Yoichi Nakazato; Koichi Okamoto
Involvement of endoplasmic reticulum stress defined by activated unfolded protein response in multiple system atrophy.
Journal of the neurological sciences 2010;297(1-2):60-5.
2010: Setsuki Tsukagoshi; Masaki Ikeda; Shinobu Tano; Kai Obayashi; Yukio Fujita; Koichi Okamoto
[Case of recurrent delayed radiation myelopathy with 5-year remission interval].
Rinshō shinkeigaku = Clinical neurology 2010;50(6):393-8.
2010: Kouki Makioka; Masaki Ikeda; Yoshio Ikeda; Ai Nakasone; Tenshi Osawa; Atsushi Sasaki; Tomohiro Otani; Masashi Arai; Koichi Okamoto
Familial amyloid polyneuropathy (Finnish type) presenting multiple cranial nerve deficits with carpal tunnel syndrome and orthostatic hypotension.
Neurological research 2010;32(5):472-5.
2010: Koichi Okamoto; Yukio Fujita; Yuji Mizuno
Pathology of protein synthesis and degradation systems in ALS.
Neuropathology : official journal of the Japanese Society of Neuropathology 2010;30(2):189-93.
2009: Koichi Okamoto
[History and classification of frontotemporal lobar degeneration].
Brain and nerve = Shinkei kenkyū no shinpo 2009;61(11):1203-8.
2009: Kouki Makioka; Tsuneo Yamazaki; Satoko Kakuda; Koichi Okamoto
Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions.
Neurological research 2009;31(9):959-68.
2009: Ai Kadokura; Tsuneo Yamazaki; Cynthia A Lemere; Masamitsu Takatama; Koichi Okamoto
Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: their relation to AD common pathology.
Neuropathology : official journal of the Japanese Society of Neuropathology 2009;29(5):566-73.
2009: Ai Kadokura; Tsuneo Yamazaki; Satoko Kakuda; Kouki Makioka; Cynthia A Lemere; Yukio Fujita; Masamitsu Takatama; Koichi Okamoto
Phosphorylation-dependent TDP-43 antibody detects intraneuronal dot-like structures showing morphological characters of granulovacuolar degeneration.
Neuroscience letters 2009;463(1):87-92.
2009: Seiya Ishibashi; Tsuneo Yamazaki; Koichi Okamoto
Association of autophagy with cholesterol-accumulated compartments in Niemann-Pick disease type C cells.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2009;16(7):954-9.
2009: Yuji Mizuno; Jeffrey R Guyon; Koichi Okamoto; Louis Kunkel
Expression of synemin in the mouse spinal cord.
Muscle & nerve 2009;39(5):634-41.
2009: Natsumi Furuta; Yukio Fujita; Akiko Sekine; Masaki Ikeda; Koichi Okamoto
[Reversible posterior leukoencephalopathy syndrome associated with carbamazepine-induced hypertension].
Rinshō shinkeigaku = Clinical neurology 2009;49(4):191-3.
2009: Masaki Ikeda; Takeshi Kawarabayashi; Yasuo Harigaya; Atsushi Sasaki; Shuichi Yamada; Etsuro Matsubara; Tetsuro Murakami; Yuya Tanaka; Tomoko Kurata; Xu Wuhua; Kenji Ueda; Hisashi Kuribara; Yasushi Ikarashi; Yoichi Nakazato; Koichi Okamoto; Koji Abe; Mikio Shoji
Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology.
Brain research 2009;1250():232-41.
2008: Koichi Okamoto
[Early symptoms of frontotemporal lobar degeneration].
Rinshō shinkeigaku = Clinical neurology 2008;48(11):999-1001.
2008: Yukio Fujita; Yuji Mizuno; Masamitsu Takatama; Koichi Okamoto
Anterior horn cells with abnormal TDP-43 immunoreactivities show fragmentation of the Golgi apparatus in ALS.
Journal of the neurological sciences 2008;269(1-2):30-4.
2008: Yukiko Hashimoto; Kazuhiro Muramatsu; Takefumi Uemura; Reiko Harada; Takashi Sato; Koichi Okamoto; Akihiro Harada
Neuron-specific and inducible recombination by Cre recombinase in the mouse.
Neuroreport 2008;19(6):621-4.
2008: Koichi Okamoto; Yuji Mizuno; Yukio Fujita
Bunina bodies in amyotrophic lateral sclerosis.
Neuropathology : official journal of the Japanese Society of Neuropathology 2008;28(2):109-15.
2008: Koichi Okamoto; Tsuneo Yamazaki; Haruhiko Banno; Gen Sobue; Mari Yoshida; Masamitsu Takatama
Neuropathological studies of patients with possible non-herpetic acute limbic encephalitis and so-called acute juvenile female non-herpetic encephalitis.
Internal medicine (Tokyo, Japan) 2008;47(4):231-6.
2007: Naoki Wada; Makoto Sohmiya; Toru Shimizu; Koichi Okamoto; Kenji Shirakura
Clinical analysis of risk factors for falls in home-living stroke patients using functional evaluation tools.
Archives of physical medicine and rehabilitation 2007;88(12):1601-5.
2007: Yuji Mizuno; Jeffrey R Guyon; Koichi Okamoto; Louis Kunkel
Synemin expression in brain.
Muscle & nerve 2007;36(4):497-504.
2007: Takeshi Tomizawa; Yoriaki Kaneko; Yuka Kaneko; Yasuyuki Saito; Hiroshi Ohnishi; Jun Okajo; Chie Okuzawa; Tomomi Ishikawa-Sekigami; Yoji Murata; Hideki Okazawa; Koichi Okamoto; Yoshihisa Nojima; Takashi Matozaki
Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):869-77.
2007: Shintaro Hayashi; Tsuneo Yamazaki; Koichi Okamoto
Nonapoptotic cell death caused by the inhibition of RNA polymerase disrupts organelle distribution.
Journal of the neurological sciences 2007;256(1-2):10-20.
2007: Shintaro Hayashi; Masakuni Amari; Masamitsu Takatama; Koichi Okamoto
Morphometric and topographical studies of small neurons in sporadic amyotrophic lateral sclerosis spinal gray matter.
Neuropathology : official journal of the Japanese Society of Neuropathology 2007;27(2):121-6.
2007: Miao Yu; Kazuo Kasai; Kazuaki Nagashima; Seiji Torii; Hiromi Yokota-Hashimoto; Koichi Okamoto; Toshiyuki Takeuchi; Hiroshi Gomi; Tetsuro Izumi
Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain.
Molecular biology of the cell 2007;18(2):688-96.
2007: Masaki Ikeda; Kazuyuki Mizushima; Yukio Fujita; Mitsunori Watanabe; Atsushi Sasaki; Kouki Makioka; Mariko Enoki; Motonobu Nakamura; Tomohiro Otani; Masamitsu Takatama; Koichi Okamoto
Familial amyloid polyneuropathy (Finnish type) in a Japanese family: Clinical features and immunocytochemical studies.
Journal of the neurological sciences 2007;252(1):4-8.
2007: Yuji Mizuno; Jeffrey R Guyon; Akiko Ishii; Sachiko Hoshino; Norio Ohkoshi; Akira Tamaoka; Koichi Okamoto; Louis Kunkel
Beta-synemin expression in cardiotoxin-injected rat skeletal muscle.
BMC musculoskeletal disorders 2007;8():40.
2006: Koichi Okamoto
[Pathomechanism of vascular dementia].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 8():769-72.
2006: Yuji Mizuno; Masakuni Amari; Masamitsu Takatama; Hitoshi Aizawa; Ban Mihara; Koichi Okamoto
Transferrin localizes in Bunina bodies in amyotrophic lateral sclerosis.
Acta neuropathologica 2006;112(5):597-603.
2006: Yuji Mizuno; Masakuni Amari; Masamitsu Takatama; Hitoshi Aizawa; Ban Mihara; Koichi Okamoto
Immunoreactivities of p62, an ubiqutin-binding protein, in the spinal anterior horn cells of patients with amyotrophic lateral sclerosis.
Journal of the neurological sciences 2006;249(1):13-8.
2006: Yukio Fujita; Eisaku Ohama; Masamitsu Takatama; Safa Al-Sarraj; Koichi Okamoto
Fragmentation of Golgi apparatus of nigral neurons with alpha-synuclein-positive inclusions in patients with Parkinson's disease.
Acta neuropathologica 2006;112(3):261-5.
2006: Yuji Mizuno; Eisaku Ohama; Junko Hirato; Yoichi Nakazato; Hitoshi Takahashi; Masamitsu Takatama; Toshiyuki Takeuchi; Koichi Okamoto
Nestin immunoreactivity of Purkinje cells in Creutzfeldt-Jakob disease.
Journal of the neurological sciences 2006;246(1-2):131-7.
2006: Kazuko Fukushima; Yuji Mizuno; Masamitsu Takatama; Koichi Okamoto
Increased neuronal expression of alpha B-crystallin in human olivary hypertrophy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2006;26(3):196-200.
2006: Mitsunori Watanabe; Mandy Jackson; Masaki Ikeda; Kazuyuki Mizushima; Masakuni Amari; Masamitsu Takatama; Shunsaku Hirai; Yoshio Ikeda; Masami Shizuka-Ikeda; Koichi Okamoto
Genetic analysis of the cystatin C gene in familial and sporadic ALS patients.
Brain research 2006;1073-1074():20-4.
2005: Masamitsu Yaguchi; Hisa Yaguchi; Tetsuro Itoh; Koichi Okamoto
Encephalopathy with isolated reversible splenial lesion of the corpus callosum.
Internal medicine (Tokyo, Japan) 2005;44(12):1291-4.
2005: Yukio Fujita; Koichi Okamoto
Golgi apparatus of the motor neurons in patients with amyotrophic lateral sclerosis and in mice models of amyotrophic lateral sclerosis.
Neuropathology : official journal of the Japanese Society of Neuropathology 2005;25(4):388-94.
2005: Yoko Suzuki; Makoto Tanaka; Makoto Sohmiya; Sachiyo Ichinose; Akira Omori; Koichi Okamoto
Identification of nitrated proteins in the normal rat brain using a proteomics approach.
Neurological research 2005;27(6):630-3.
2005: Masaki Ikeda; Mikio Shoji; Toshitaka Kawarai; Takeshi Kawarabayashi; Etsuro Matsubara; Tetsuro Murakami; Atsushi Sasaki; Yasushi Tomidokoro; Yasushi Ikarashi; Hisashi Kuribara; Koichi Ishiguro; Masato Hasegawa; Shu-Hui C. Yen; M Azhar Chishti; Yasuo Harigaya; Koji Abe; Koichi Okamoto; Peter St George-Hyslop; David Westaway
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice.
The American journal of pathology 2005;166(2):521-31.
2005: Makoto Sohmiya; Makoto Tanaka; Yoko Suzuki; Yutaka Tanino; Koichi Okamoto; Yorihiro Yamamoto
An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients.
Journal of the neurological sciences 2005;228(1):49-53.
2004: Masamitsu Yaguchi; Yukio Fujita; Masakuni Amari; Masamitsu Takatama; Safa Al-Sarraj; Peter N Leigh; Koichi Okamoto
Morphological differences of intraneuronal ubiquitin-positive inclusions in the dentate gyrus and parahippocampal gyrus of motor neuron disease with dementia.
Neuropathology : official journal of the Japanese Society of Neuropathology 2004;24(4):296-301.
2004: Yuichi Tashiro; Tsuneo Yamazaki; Yukiko Shimada; Yoshiko Ohno-Iwashita; Koichi Okamoto
Axon-dominant localization of cell-surface cholesterol in cultured hippocampal neurons and its disappearance in Niemann-Pick type C model cells.
The European journal of neuroscience 2004;20(8):2015-21.
2004: Yuji Mizuno; Jeffrey R Guyon; simon simon watkins; Kazuyuki Mizushima; Toshikuni Sasaoka; Michihiro Imamura; Louis Kunkel; Koichi Okamoto
Beta-synemin localizes to regions of high stress in human skeletal myofibers.
Muscle & nerve 2004;30(3):337-46.
2004: Makoto Sohmiya; Makoto Tanaka; Nyou Wei Tak; Makoto Yanagisawa; Yutaka Tanino; Yoko Suzuki; Koichi Okamoto; Yorihiro Yamamoto
Redox status of plasma coenzyme Q10 indicates elevated systemic oxidative stress in Parkinson's disease.
Journal of the neurological sciences 2004;223(2):161-6.
2004: Yuji Mizuno; Toshiyuki Takeuchi; Masamitsu Takatama; Koichi Okamoto
Expression of nestin in ballooned neurons in patients with Creutzfeldt-Jakob disease.
Neuroscience letters 2004;366(2):144-7.
2004: Yuka Sakazume; Makoto Tanaka; Itsuo Isobe; Rika Tominaga; Eiji Nanba; Koichi Okamoto
[A case of middle-aged onset sialidosis type I].
Rinshō shinkeigaku = Clinical neurology 2004;44(8):541-4.
2004: Makoto Sohmiya; Makoto Tanaka; Koichi Okamoto; Akio Fujisawa; Yorihiro Yamamoto
Synergistic inhibition of lipid peroxidation by vitamin E and a dopamine agonist, cabergoline.
Neurological research 2004;26(4):418-21.
2004: Koichi Okamoto
[Differential diagnosis between cerebrovascular dementia and Alzheimer disease].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 4():141-6.
2004: Makoto Sohmiya; Makoto Tanaka; Yoshiaki Aihara; Koichi Okamoto
Structural changes in the midbrain with aging and Parkinson's disease: an MRI study.
Neurobiology of aging 2004;25(4):449-53.
2004: Yukifusa Igeta; Koichi Ishiguro; Koichi Okamoto
[An adult case of bacterial meningitis caused by penicillin-resistant streptococcus pneumoniae].
Rinshō shinkeigaku = Clinical neurology 2004;44(3):154-9.
2004: Koichi Okamoto
[The coexistence of vascular dementia and Alzheimer's disease].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl():201-5.
2003: Yuji Mizuno; Toshiyuki Takeuchi; Masamitsu Takatama; Koichi Okamoto
Expression of nestin in Purkinje cells in patients with Creutzfeldt-Jakob disease.
Neuroscience letters 2003;352(2):109-12.
2003: Chieko Inoue; Yoshio Ikeda; Makoto Tanaka; Yuka Sakazume; Koichi Okamoto
A case of mixed connective tissue disease showing a lymphoid follicle in muscle pathology.
Journal of the neurological sciences 2003;215(1-2):119-21.
2003: Yoko Suzuki; Makoto Tanaka; Makoto Sohmiya; Toshihiko Yoshida; Koichi Okamoto
Antioxidant properties of carvedilol: inhibition of lipid peroxidation, protein oxidation and superoxide generation.
Neurological research 2003;25(7):749-53.
2003: Masamitsu Yaguchi; Ai Nakasone; Makoto Sohmiya; Futoshi Saitoh; Nariyuki Ohya; Takatomo Yoshida; Yoichi Nakazato; Koichi Okamoto
Gliomatosis cerebri involving the lumbosacral spinal cord.
Internal medicine (Tokyo, Japan) 2003;42(7):615-8.
2003: Yuji Mizuno; Seiji Hori; Akira Kakizuka; Koichi Okamoto
Vacuole-creating protein in neurodegenerative diseases in humans.
Neuroscience letters 2003;343(2):77-80.
2003: Makoto Tanaka; Taku Ichiba; Susumu Kondo; Shunsaku Hirai; Koichi Okamoto
Cerebral blood flow and oxygen metabolism in patients with progressive dementia and amyotrophic lateral sclerosis.
Neurological research 2003;25(4):351-6.
2003: Masamitsu Yaguchi; Yoshio Hashizume; Mari Yoshida; Nicholas K Gonatas; Koichi Okamoto
Reduction of the size of the Golgi apparatus of spinal anterior horn cells in patients with X-linked spinal and bulbar muscular atrophy.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2003;4(1):17-21.
2003: Masamitsu Yaguchi; Kazuaki Nagashima; Tetsuro Izumi; Koichi Okamoto
Neuropathological study of C57BL/6Akita mouse, type 2 diabetic model: enhanced expression of alphaB-crystallin in oligodendrocytes.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(1):44-50.
2003: Masamitsu Yaguchi; Koichi Okamoto; Yoichi Nakazato
Frontotemporal dementia with cerebral intraneuronal ubiquitin-positive inclusions but lacking lower motor neuron involvement.
Acta neuropathologica 2003;105(1):81-5.
2002: Koichi Okamoto; Makoto Tanaka; Susumu Kondo
Treatment of vascular dementia.
Annals of the New York Academy of Sciences 2002;977():507-12.
2002: Makoto Tanaka; Koichi Okamoto; Shunsaku Hirai
Cerebral blood flow and oxygen metabolism in vascular dementia evaluated by positron emission tomography: importance of frontal lobe hypoperfusion and hypometabolism.
Annals of the New York Academy of Sciences 2002;977():135-40.
2002: Shinobu Tano; Yukiko Hashimoto; Yuji Mizuno; Makoto Tanaka; Koichi Okamoto
[A case of herpes simplex encephalitis with noticeable findings of SPECT].
Rinshō shinkeigaku = Clinical neurology 2002;42(10):966-9.
2002: Toshihiko Yoshida; Makoto Tanaka; Yoko Suzuki; Makoto Sohmiya; Koichi Okamoto
Antioxidant properties of cabergoline: inhibition of brain auto-oxidation and superoxide anion production of microglial cells in rats.
Neuroscience letters 2002;330(1):1-4.
2002: Makoto Uesugi; Koichi Okamoto; Makoto Tanaka; Nicholas K Gonatas
Masses of phosphorylated neurofilaments are associated with abnormal golgi apparatus of anterior horn neurons of beta, beta'-iminodipropionitrile-intoxicated rats.
Neuropathology : official journal of the Japanese Society of Neuropathology 2002;22(2):61-5.
2002: Toshihiko Yoshida; Makoto Tanaka; Koichi Okamoto
Immunoglobulin G induces microglial superoxide production.
Neurological research 2002;24(4):361-4.
2002: Atsushi Sakurai; Koichi Okamoto; Masamitsu Yaguchi; Yukio Fujita; Yuji Mizuno; Yoichi Nakazato; Nicholas K Gonatas
Pathology of the inferior olivary nucleus in patients with multiple system atrophy.
Acta neuropathologica 2002;103(6):550-4.
2002: Kazuaki Nagashima; Seiji Torii; Zhaohong Yi; Michihiro Igarashi; Koichi Okamoto; Toshiyuki Takeuchi; Tetsuro Izumi
Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions.
FEBS letters 2002;517(1-3):233-8.
2002: Masami Shizuka-Ikeda; Etsuro Matsubara; Masaki Ikeda; Mitsuyasu Kanai; Yasushi Tomidokoro; Yoshio Ikeda; Mitsunori Watanabe; Takeshi Kawarabayashi; Yasuo Harigaya; Koichi Okamoto; Kei Maruyama; Eduardo M Castaño; Peter St George-Hyslop; Mikio Shoji
Generation of amyloid beta protein from a presenilin-1 and betaAPP complex.
Biochemical and biophysical research communications 2002;292(2):571-8.
2002: Yukio Fujita; Koichi Okamoto; Atsushi Sakurai; Hirofumi Kusaka; Hitoshi Aizawa; Ban Mihara; Nicholas K Gonatas
The Golgi apparatus is fragmented in spinal cord motor neurons of amyotrophic lateral sclerosis with basophilic inclusions.
Acta neuropathologica 2002;103(3):243-7.
2001: Koichi Okamoto; Yoshio Ikeda
[Channelopathy].
Rinshō shinkeigaku = Clinical neurology 2001;41(12):1226-8.
2001: Masamitsu Karasawa; Norifumi Tsukamoto; Arito Yamane; Koichi Okamoto; Tadashi Maehara; Akihiko Yokohama; Yoshihisa Nojima; M Omine
Analysis of the distribution of CAG repeats and X-chromosome inactivation status of HUMARA gene in healthy female subjects using improved fluorescence-based assay.
International journal of hematology 2001;74(3):281-6.
2001: Yasushi Tomidokoro; Yasuo Harigaya; Etsuro Matsubara; Masaki Ikeda; Takeshi Kawarabayashi; Tomoaki Shirao; Koichi Ishiguro; Koichi Okamoto; Steven G Younkin; Mikio Shoji
Brain Abeta amyloidosis in APPsw mice induces accumulation of presenilin-1 and tau.
The Journal of pathology 2001;194(4):500-6.
2001: Y Aihara; Tomio Inoue; T Tashiro; Koichi Okamoto; Yoshiaki Komiya; K Mikoshiba
Movement of endoplasmic reticulum in the living axon is distinct from other membranous vesicles in its rate, form, and sensitivity to microtubule inhibitors.
Journal of neuroscience research 2001;65(3):236-46.
2001: Shintaro Hayashi; Atsushi Sakurai; Masakuni Amari; Koichi Okamoto
Pathological study of the diffuse myelin pallor in the anterolateral columns of the spinal cord in amyotrophic lateral sclerosis.
Journal of the neurological sciences 2001;188(1-2):3-7.
2001: Makoto Sohmiya; Makoto Tanaka; Yoshiaki Aihara; Shunsaku Hirai; Koichi Okamoto
Age-related structural changes in the human midbrain: an MR image study.
Neurobiology of aging 2001;22(4):595-601.
2001: Makoto Kamiya; H Yamanouchi; T Yoshida; Hanako Arai; Hideaki Yokoo; Atsushi Sasaki; Junko Hirato; Yoichi Nakazato; Yuka Sakazume; Koichi Okamoto
Ataxia telangiectasia with vascular abnormalities in the brain parenchyma: report of an autopsy case and literature review.
Pathology international 2001;51(4):271-6.
2001: Makoto Sohmiya; Makoto Tanaka; A Sotomatsu; Yoshiaki Aihara; Koichi Okamoto
[Three elderly cases of hyperostosis cranii with various clinical symptoms].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2001;38(2):218-23.
2001: Mikio Shoji; Mitsuyasu Kanai; Etsuro Matsubara; Yasushi Tomidokoro; M Shizuka; Yoshio Ikeda; Masaki Ikeda; Yasuo Harigaya; Koichi Okamoto; Shunsaku Hirai
The levels of cerebrospinal fluid Abeta40 and Abeta42(43) are regulated age-dependently.
Neurobiology of aging 2001;22(2):209-15.
2001: H Takenoshita; Masami Shizuka-Ikeda; Hiroshi Mitoma; S Song; Yasuo Harigaya; Yukifusa Igeta; Masamitsu Yaguchi; Kazuyuki Ishida; Mikio Shoji; Makoto Tanaka; Hidehiro Mizusawa; Koichi Okamoto
Presynaptic inhibition of cerebellar GABAergic transmission by glutamate decarboxylase autoantibodies in progressive cerebellar ataxia.
Journal of neurology, neurosurgery, and psychiatry 2001;70(3):386-9.
2001: Yasushi Tomidokoro; Koichi Ishiguro; Yasuo Harigaya; Etsuro Matsubara; Masaki Ikeda; J M Park; K Yasutake; Takeshi Kawarabayashi; Koichi Okamoto; Mikio Shoji
Abeta amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice.
Neuroscience letters 2001;299(3):169-72.
2001: Toshihiko Yoshida; Makoto Tanaka; Koichi Okamoto
Inhibitory effect of nicergoline on superoxide generation by activated rat microglias measured using a simple chemiluminescence method.
Neuroscience letters 2001;297(1):5-8.
2000: Yoshio Ikeda; Masami Shizuka-Ikeda; Mitsunori Watanabe; M Schmitt; Koichi Okamoto; Mikio Shoji
Asymptomatic CTG expansion at the SCA8 locus is associated with cerebellar atrophy on MRI.
Journal of the neurological sciences 2000;182(1):76-9.
2000: K Takamine; Koichi Okamoto; Yukio Fujita; Atsushi Sakurai; Masamitsu Takatama; Nicholas K Gonatas
The involvement of the neuronal Golgi apparatus and trans-Golgi network in the human olivary hypertrophy.
Journal of the neurological sciences 2000;182(1):45-50.
2000: Yasushi Tomidokoro; Yasuo Harigaya; Etsuro Matsubara; Masaki Ikeda; Takeshi Kawarabayashi; Koichi Okamoto; Mikio Shoji
Impaired neurotransmitter systems by Abeta amyloidosis in APPsw transgenic mice overexpressing amyloid beta protein precursor.
Neuroscience letters 2000;292(3):155-8.
2000: Atsushi Sakurai; Koichi Okamoto; Yukio Fujita; Yoichi Nakazato; K Wakabayashi; H Takahashi; Nicholas K Gonatas
Fragmentation of the Golgi apparatus of the ballooned neurons in patients with corticobasal degeneration and Creutzfeldt-Jakob disease.
Acta neuropathologica 2000;100(3):270-4.
2000: Mikio Shoji; Takeshi Kawarabayashi; M Sato; A Sasaki; Takaomi C Saido; Etsuro Matsubara; Yasushi Tomidokoro; Mitsuyasu Kanai; M Shizuka; Koichi Ishiguro; Masaki Ikeda; Yasuo Harigaya; Koichi Okamoto; Shunsaku Hirai
Age-related amyloid beta protein accumulation induces cellular death and macrophage activation in transgenic mice.
The Journal of pathology 2000;191(1):93-101.
2000: Mikio Shoji; Yasuo Harigaya; A Sasaki; K Uéda; Koichi Ishiguro; Etsuro Matsubara; Mitsunori Watanabe; Masaki Ikeda; Mitsuyasu Kanai; Yasushi Tomidokoro; M Shizuka; Masakuni Amari; Kenji Kosaka; Yoichi Nakazato; Koichi Okamoto; Shunsaku Hirai
Accumulation of NACP/alpha-synuclein in lewy body disease and multiple system atrophy.
Journal of neurology, neurosurgery, and psychiatry 2000;68(5):605-8.
2000: Yukio Fujita; Koichi Okamoto; Atsushi Sakurai; Nicholas K Gonatas; Asao Hirano
Fragmentation of the Golgi apparatus of the anterior horn cells in patients with familial amyotrophic lateral sclerosis with SOD1 mutations and posterior column involvement.
Journal of the neurological sciences 2000;174(2):137-40.
2000: Yoshio Ikeda; M Shizuka; Mitsunori Watanabe; Koichi Okamoto; Mikio Shoji
Molecular and clinical analyses of spinocerebellar ataxia type 8 in Japan.
Neurology 2000;54(4):950-5.
2000: Mikio Shoji; Takeshi Kawarabayashi; Etsuro Matsubara; Masaki Ikeda; Koichi Ishiguro; Yasuo Harigaya; Koichi Okamoto
Distribution of amyloid beta protein precursor in the Alzheimer's disease brain.
Psychiatry and clinical neurosciences 2000;54(1):45-54.
2000: Makoto Sohmiya; Makoto Tanaka; Koichi Okamoto
[Chronic hypertrophic cranial pachymeningitis].
Ryōikibetsu shōkōgun shirīzu 2000;(31):77-80.
1999: Yuka Sakazume; M Shizuka; Makoto Tanaka; Koichi Okamoto; Y Hayashi
[Sensory ataxic neuropathy presenting anti-a-fodrin antibody associated with rheumatoid arthritis].
Rinshō shinkeigaku = Clinical neurology 1999;39(9):935-9.
1999: Toshihiko Yoshida; Makoto Tanaka; A Sotomatsu; Koichi Okamoto
Effect of methylprednisolone-pulse therapy on superoxide production of neutrophils.
Neurological research 1999;21(5):509-12.
1999: Makoto Tanaka; Toshihiko Yoshida; Koichi Okamoto; Shunsaku Hirai
Dopamine and DOPA cause release of iron from ferritin and lipid peroxidation of liposomes.
Neuroreport 1999;10(9):1883-7.
1999: Mitsuyasu Kanai; M Shizuka; Katsuya Urakami; Etsuro Matsubara; Yasuo Harigaya; Koichi Okamoto; Mikio Shoji
Apolipoprotein E4 accelerates dementia and increases cerebrospinal fluid tau levels in Alzheimer's disease.
Neuroscience letters 1999;267(1):65-8.
1999: Etsuro Matsubara; Jorge Ghiso; Blas Frangione; Masakuni Amari; Yasushi Tomidokoro; Yoshio Ikeda; Yasuo Harigaya; Koichi Okamoto; Mikio Shoji
Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome.
Annals of neurology 1999;45(4):537-41.
1999: Yasushi Tomidokoro; Koichi Ishiguro; Yukifusa Igeta; Etsuro Matsubara; Mitsuyasu Kanai; M Shizuka; Takeshi Kawarabayashi; Yasuo Harigaya; S Kawakatsu; K Ii; Masaki Ikeda; Peter St George-Hyslop; Shunsaku Hirai; Koichi Okamoto; Mikio Shoji
Carboxyl-terminal fragments of presenilin-1 are closely related to cytoskeletal abnormalities in Alzheimer's brains.
Biochemical and biophysical research communications 1999;256(3):512-8.
1999: Masamitsu Karasawa; Norifumi Tsukamoto; H Sakai; Koichi Okamoto; Tadashi Maehara; T Naruse; K Morita; S Sato
Clinical outcome in three patients with myelodysplastic syndrome showing polyclonal hematopoiesis.
Acta haematologica 1999;101(1):46-9.
1999: Yukio Fujita; Koichi Okamoto; Atsushi Sakurai; Masakuni Amari; Yoichi Nakazato; Nicholas K Gonatas
Fragmentation of the Golgi apparatus of Betz cells in patients with amyotrophic lateral sclerosis.
Journal of the neurological sciences 1999;163(1):81-5.
1999: Kazuyuki Mizushima; Mitsunori Watanabe; I Kondo; Koichi Okamoto; M Shizuka; Koji Abe; M Aoki; Mikio Shoji
Analysis of spinocerebellar ataxia type 2 gene and haplotype analysis: (CCG)1-2 polymorphism and contribution to founder effect.
Journal of medical genetics 1999;36(2):112-4.
1999: Masamitsu Yaguchi; Koichi Okamoto
[Cockayne syndrome].
Ryōikibetsu shōkōgun shirīzu 1999;(27 Pt 2):411-3.
1998: M Shizuka; Mitsunori Watanabe; Yoshio Ikeda; Kazuyuki Mizushima; Koichi Okamoto; Mikio Shoji
Molecular analysis of a de novo mutation for spinocerebellar ataxia type 6 and (CAG)n repeat units in normal elder controls.
Journal of the neurological sciences 1998;161(1):85-7.
1998: Mitsunori Watanabe; Y Sugai; P Concannon; M Koenig; M Schmitt; M Sato; M Shizuka; Kazuyuki Mizushima; Yoshio Ikeda; Yasushi Tomidokoro; Koichi Okamoto; Mikio Shoji
Familial spinocerebellar ataxia with cerebellar atrophy, peripheral neuropathy, and elevated level of serum creatine kinase, gamma-globulin, and alpha-fetoprotein.
Annals of neurology 1998;44(2):265-9.
1998: Mitsuyasu Kanai; Etsuro Matsubara; K Isoe; Katsuya Urakami; K Nakashima; Heii Arai; Hidetada Sasaki; Koji Abe; Takeshi Iwatsubo; T Kosaka; Mitsunori Watanabe; Yasushi Tomidokoro; M Shizuka; Kazuyuki Mizushima; T Nakamura; Yukifusa Igeta; Yoshio Ikeda; Masakuni Amari; Takeshi Kawarabayashi; Koichi Ishiguro; Yasuo Harigaya; K Wakabayashi; Koichi Okamoto; Shunsaku Hirai; Mikio Shoji
Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan.
Annals of neurology 1998;44(1):17-26.
1998: S Kano; Mitsunori Watanabe; Mitsuyasu Kanai; R Koike; Osamu Onodera; S Tsuji; Koichi Okamoto; Mikio Shoji
A Japanese family with adrenoleukodystrophy with a codon 291 deletion: a clinical, biochemical, pathological, and genetic report.
Journal of the neurological sciences 1998;158(2):187-92.
1998: Mikio Shoji; Etsuro Matsubara; Mitsuyasu Kanai; Mitsunori Watanabe; T Nakamura; Yasushi Tomidokoro; M Shizuka; K Wakabayashi; Yukifusa Igeta; Yoshio Ikeda; Kazuyuki Mizushima; Masakuni Amari; Koichi Ishiguro; Takeshi Kawarabayashi; Yasuo Harigaya; Koichi Okamoto; Shunsaku Hirai
Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease.
Journal of the neurological sciences 1998;158(2):134-40.
1998: Toshihiko Yoshida; Makoto Tanaka; A Sotomatsu; Shunsaku Hirai; Koichi Okamoto
Activated microglia cause iron-dependent lipid peroxidation in the presence of ferritin.
Neuroreport 1998;9(9):1929-33.
1998: Makoto Tanaka; Toshihiko Yoshida; Koichi Okamoto; Shunsaku Hirai
Antioxidant properties of nicergoline; inhibition of brain auto-oxidation and superoxide production of neutrophils in rats.
Neuroscience letters 1998;248(1):68-72.
1998: Kazuyuki Mizushima; Mitsunori Watanabe; Koji Abe; M Aoki; Y Itoyama; M Shizuka; Koichi Okamoto; Mikio Shoji
Analysis of spinocerebellar ataxia type 2 in Gunma Prefecture in Japan: CAG trinucleotide expansion and clinical characteristics.
Journal of the neurological sciences 1998;156(2):180-5.
1998: Mikio Shoji; Takeshi Kawarabayashi; M Sato; A Sasaki; Etsuro Matsubara; Yukifusa Igeta; Mitsuyasu Kanai; Yasushi Tomidokoro; M Shizuka; Koichi Ishiguro; Yasuo Harigaya; Koichi Okamoto; Shunsaku Hirai
Accumulation of amyloid beta protein in transgenic mice.
Neurobiology of aging 1998;19(1 Suppl):S59-63.
1998: Toshihiko Yoshida; Makoto Tanaka; A Sotomatsu; Koichi Okamoto; Shunsaku Hirai
Serum of Behçet's disease enhances superoxide production of normal neutrophils.
Free radical research 1998;28(1):39-44.
1997: Yukifusa Igeta; Takeshi Kawarabayashi; M Sato; N Yamada; Etsuro Matsubara; Koichi Ishiguro; Mitsuyasu Kanai; Yasushi Tomidokoro; J Osuga; Koichi Okamoto; Shunsaku Hirai; Mikio Shoji
Apolipoprotein E accumulates with the progression of A beta deposition in transgenic mice.
Journal of neuropathology and experimental neurology 1997;56(11):1228-35.
1997: M Shizuka; Mitsunori Watanabe; M Aoki; Yoshio Ikeda; Kazuyuki Mizushima; Koichi Okamoto; Y Itoyama; Koji Abe; Mikio Shoji
Analysis of the McLeod syndrome gene in three patients with neuroacanthocytosis.
Journal of the neurological sciences 1997;150(2):133-5.
1997: Takeshi Kawarabayashi; Yukifusa Igeta; M Sato; A Sasaki; Etsuro Matsubara; Mitsuyasu Kanai; Yasushi Tomidokoro; Koichi Ishiguro; Koichi Okamoto; Shunsaku Hirai; Mikio Shoji
Lysosomal generation of amyloid beta protein species in transgenic mice.
Brain research 1997;765(2):343-8.
1997: S Tanaka; Makoto Tanaka; N Wada; Koichi Okamoto; Shunsaku Hirai; K Tanaka
[Uncoupling of cerebellar blood flow and metabolism in paraneoplastic cerebellar degeneration: report of a case].
Rinshō shinkeigaku = Clinical neurology 1997;37(6):514-9.
1997: T Arai; Yasushi Ikarashi; Koichi Okamoto; Hisashi Kuribara; Yuji Maruyama
Memory disturbance and hippocampal degeneration induced by continuous intraventricular infusion of a protease inhibitor, leupeptin.
Brain research 1997;754(1-2):157-62.
1997: M Tanaka; S Kondo; Koichi Okamoto; Shunsaku Hirai
[Cerebral perfusion and oxygen metabolism in Parkinson's disease: positron emission tomographic study using oxygen-15-labeled CO2 and O2].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(1):218-21.