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Hitoshi Okamura

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Anatomy

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Circadian Rhythm

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Akira Hashiramoto; Takashi Yamane; Ken Tsumiyama; Kohsuke Yoshida; Koichiro Komai; Hiroyuki Yamada; Fumiyoshi Yamazaki; Masao Doi; Hitoshi Okamura; Shunichi Shiozawa
Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.
Kyoko Yako; M Sasano; K Miki; Hirofumi Sakai; M Dozono; D Frekers; M B Greenfield; K Hatanaka; E Ihara; M Kato; T Kawabata; Hiroshi Kuboki; Y Maeda; H Matsubara; K Muto; S Noji; Hitoshi Okamura; Taijiro Okabe; S Sakaguchi; Y Sakemi; Y Sasamoto; K Sekiguchi; Yoshihiro Shimizu; K Suda; Y Tameshige; A Tamii; T Uesaka; T Wakasa; H Zheng
Gamow-Teller strength distributions in 48Sc by the 48Ca(p,n) and 48Ti(n,p) reactions and two-neutrino double-beta decay nuclear matrix elements.
Yasuhide Fukatsu; Tetsuya Noguchi; Tetsuya Hosooka; Takeshi Ogura; Ko Kotani; Takaya Abe; Tetsuro Shibakusa; Kazuo Inoue; Mashito Sakai; Kazutoshi Tobimatsu; Kenjiro Inagaki; Toyo Yoshioka; Masahiro Matsuo; Jun Nakae; Yasushi Matsuki; Ryuji Hiramatsu; Kohei Kaku; Hitoshi Okamura; Tohru Fushiki; Masato Kasuga
Muscle-specific overexpression of heparin-binding epidermal growth factor-like growth factor increases peripheral glucose disposal and insulin sensitivity.

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All Publications

2010: Akira Hashiramoto; Takashi Yamane; Ken Tsumiyama; Kohsuke Yoshida; Koichiro Komai; Hiroyuki Yamada; Fumiyoshi Yamazaki; Masao Doi; Hitoshi Okamura; Shunichi Shiozawa
Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1560-5.
2009: Kyoko Yako; M Sasano; K Miki; Hirofumi Sakai; M Dozono; D Frekers; M B Greenfield; K Hatanaka; E Ihara; M Kato; T Kawabata; Hiroshi Kuboki; Y Maeda; H Matsubara; K Muto; S Noji; Hitoshi Okamura; Taijiro Okabe; S Sakaguchi; Y Sakemi; Y Sasamoto; K Sekiguchi; Yoshihiro Shimizu; K Suda; Y Tameshige; A Tamii; T Uesaka; T Wakasa; H Zheng
Gamow-Teller strength distributions in 48Sc by the 48Ca(p,n) and 48Ti(n,p) reactions and two-neutrino double-beta decay nuclear matrix elements.
Physical review letters 2009;103(1):012503.
2009: Yasuhide Fukatsu; Tetsuya Noguchi; Tetsuya Hosooka; Takeshi Ogura; Ko Kotani; Takaya Abe; Tetsuro Shibakusa; Kazuo Inoue; Mashito Sakai; Kazutoshi Tobimatsu; Kenjiro Inagaki; Toyo Yoshioka; Masahiro Matsuo; Jun Nakae; Yasushi Matsuki; Ryuji Hiramatsu; Kohei Kaku; Hitoshi Okamura; Tohru Fushiki; Masato Kasuga
Muscle-specific overexpression of heparin-binding epidermal growth factor-like growth factor increases peripheral glucose disposal and insulin sensitivity.
Endocrinology 2009;150(6):2683-91.
2009: Miki Tanioka; Hiroyuki Yamada; Masao Doi; Hideki Bando; Yoshiaki Yamaguchi; Chikako Nishigori; Hitoshi Okamura
Molecular clocks in mouse skin.
The Journal of investigative dermatology 2009;129(5):1225-31.
2009: Yoko Masuda; Noriaki Emoto; Hidemi Nonaka; Kazuhiro Yagita; Takeshi Todo; Hitoshi Okamura; Mitsuhiro Yokoyama; Ken-ichi Hirata
Role of angiotensin and the clock system in the circadian regulation of plasminogen activator inhibitor-1.
The Kobe journal of medical sciences 2009;54(6):E264-71.
2008: Takeshi Nishio; Hideki Bando; Hitoshi Bamba; Yasuo Hisa; Hitoshi Okamura
Circadian gene expression in the murine larynx.
Auris, nasus, larynx 2008;35(4):539-44.
2008: Naonobu Nishino; Yoshikazu Tamori; Sanshiro Tateya; Takayuki Kawaguchi; Tetsuro Shibakusa; Wataru Mizunoya; Kazuo Inoue; Riko Kitazawa; Sohei Kitazawa; Yasushi Matsuki; Ryuji Hiramatsu; Satoru Masubuchi; Asako Omachi; Kazuhiro Kimura; Masayuki Saito; Taku Amo; Shigeo Ohta; Tomohiro Yamaguchi; Takashi Osumi; Jinglei Cheng; Toyoshi Fujimoto; Harumi Nakao; Kazuki Nakao; Atsu Aiba; Hitoshi Okamura; Tohru Fushiki; Masato Kasuga
FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets.
The Journal of clinical investigation 2008;118(8):2808-21.
2008: T Fukuyama; Masao Doi; Masahiro Matsuo; Hiromi Nishinaga; Shigeru Miyake; Hitoshi Okamura
Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus.
Biomedical research (Tokyo, Japan) 2008;29(2):93-8.
2007: Hideki Bando; Takeshi Nishio; Gijsbertus T J van der Horst; Satoru Masubuchi; Yasuo Hisa; Hitoshi Okamura
Vagal regulation of respiratory clocks in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(16):4359-65.
2007: Hiroyuki Fukuya; Noriaki Emoto; Hidemi Nonaka; Kazuhiro Yagita; Hitoshi Okamura; Mitsuhiro Yokoyama
Circadian expression of clock genes in human peripheral leukocytes.
Biochemical and biophysical research communications 2007;354(4):924-8.
2006: Naoko Hashimoto; Yoshiaki Kido; Tohru Uchida; Shun-ichiro Asahara; Yutaka Shigeyama; Tomokazu Matsuda; Akihiko Takeda; Daisuke Tsuchihashi; Akihiko Nishizawa; Wataru Ogawa; Yoshito Fujimoto; Hitoshi Okamura; Karen C Arden; Pedro L Herrera; Tetsuo Noda; Masato Kasuga
Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass.
Nature genetics 2006;38(5):589-93.
2006: Yoshito Fujimoto; Kazuhiro Yagita; Hitoshi Okamura
Does mPER2 protein oscillate without its coding mRNA cycling?: post-transcriptional regulation by cell clock.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(5):525-30.
2006: Hiroshi Inoue; Wataru Ogawa; Akihiro Asakawa; Yasuo Okamoto; Akihiko Nishizawa; Michihiro Matsumoto; Kiyoshi Teshigawara; Yasushi Matsuki; Eijiro Watanabe; Ryuji Hiramatsu; Kenji Notohara; Koji Katayose; Hitoshi Okamura; C Ronald Kahn; Tetsuo Noda; Kiyoshi Takeda; Shizuo Akira; Akio Inui; Masato Kasuga
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.
Cell metabolism 2006;3(4):267-75.
2006: Inês Chaves; Kazuhiro Yagita; Sander Barnhoorn; Hitoshi Okamura; Gijsbertus T J van der Horst; Filippo Tamanini
Functional evolution of the photolyase/cryptochrome protein family: importance of the C terminus of mammalian CRY1 for circadian core oscillator performance.
Molecular and cellular biology 2006;26(5):1743-53.
2005: Atsushi Ishida; Tatsushi Mutoh; Tomoko Ueyama; Hideki Bando; Satoru Masubuchi; Daiichiro Nakahara; Gozoh Tsujimoto; Hitoshi Okamura
Light activates the adrenal gland: timing of gene expression and glucocorticoid release.
Cell metabolism 2005;2(5):297-307.
2005: Hitoshi Okamura
[Molecular mechanisms of circadian clock: how digestive organs tick?].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2005;102(10):1259-66.
2005: Satoru Masubuchi; Noritoshi Kataoka; Paolo Sassone-Corsi; Hitoshi Okamura
Mouse Period1 (mPER1) acts as a circadian adaptor to entrain the oscillator to environmental light/dark cycles by regulating mPER2 protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(19):4719-24.
2005: Xin Dong; Kazuhiro Yagita; Jing Zhang; Hitoshi Okamura
Expression of ubiquitin-related enzymes in the suprachiasmatic nucleus with special reference to ubiquitin carboxy-terminal hydrolase UchL1.
Biomedical research (Tokyo, Japan) 2005;26(2):43-9.
2005: Mohammad Saifur Rohman; Noriaki Emoto; Hidemi Nonaka; Ryusuke Okura; MASATAKA NISHIMURA; Kazuhiro Yagita; Gijsbertus T J van der Horst; Masafumi Matsuo; Hitoshi Okamura; Mitsuhiro Yokoyama
Circadian clock genes directly regulate expression of the Na(+)/H(+) exchanger NHE3 in the kidney.
Kidney international 2005;67(4):1410-9.
2005: Yoshinobu Yamamoto; Kazuhiro Yagita; Hitoshi Okamura
Role of cyclic mPer2 expression in the mammalian cellular clock.
Molecular and cellular biology 2005;25(5):1912-21.
2005: Daisuke Matsui; Shigeki Takekida; Hitoshi Okamura
Molecular oscillation of Per1 and Per2 genes in the rodent brain: an in situ hybridization and molecular biological study.
The Kobe journal of medical sciences 2005;51(5-6):85-93.
2005: Filippo Tamanini; Kazuhiro Yagita; Hitoshi Okamura; Gijsbertus T J van der Horst
Nucleocytoplasmic shuttling of clock proteins.
Methods in enzymology 2005;393():418-35.
2004: Hitoshi Okamura
Clock genes in cell clocks: roles, actions, and mysteries.
Journal of biological rhythms 2004;19(5):388-99.
2004: Jing Zhang; Xin Dong; Yoshito Fujimoto; Hitoshi Okamura
Molecular signals of Mammalian circadian clock.
The Kobe journal of medical sciences 2004;50(3-4):101-9.
2003: Kunihiko Kawamoto; Mamoru Nagano; Fumio Kanda; Kazuo Chihara; Yasufumi Shigeyoshi; Hitoshi Okamura
Two types of VIP neuronal components in rat suprachiasmatic nucleus.
Journal of neuroscience research 2003;74(6):852-7.
2003: Shun Yamaguchi; Hiromi Isejima; Takuya Matsuo; Ryusuke Okura; Kazuhiro Yagita; Masaki Kobayashi; Hitoshi Okamura
Synchronization of cellular clocks in the suprachiasmatic nucleus.
Science (New York, N.Y.) 2003;302(5649):1408-12.
2003: Takuya Matsuo; Shun Yamaguchi; Shigeru Mitsui; Aki Emi; Fukuko Shimoda; Hitoshi Okamura
Control mechanism of the circadian clock for timing of cell division in vivo.
Science (New York, N.Y.) 2003;302(5643):255-9.
2003: Hidehito Kimura; Xing Dong; Kazuhiro Yagita; Hitoshi Okamura
Brain expression of apurinic/apyrimidinic endonuclease (APE/Ref-1) multifunctional DNA repair enzyme gene in the mouse with special reference to the suprachiasmatic nucleus.
Neuroscience research 2003;46(4):443-52.
2003: Takao Mohri; Noriaki Emoto; Hidemi Nonaka; Hiroyuki Fukuya; Kazuhiro Yagita; Hitoshi Okamura; Mitsuhiro Yokoyama
Alterations of circadian expressions of clock genes in Dahl salt-sensitive rats fed a high-salt diet.
Hypertension 2003;42(2):189-94.
2003: Hitoshi Okamura
Integration of mammalian circadian clock signals: from molecule to behavior.
The Journal of endocrinology 2003;177(1):3-6.
2003: Tatsushi Mutoh; Shigenobu Shibata; Horst-Werner Korf; Hitoshi Okamura
Melatonin modulates the light-induced sympathoexcitation and vagal suppression with participation of the suprachiasmatic nucleus in mice.
The Journal of physiology 2003;547(Pt 1):317-32.
2003: Hitoshi Okamura
Integration of molecular rhythms in the mammalian circadian system.
Novartis Foundation symposium 2003;253():161-70, discussion 102-9, 281-4.
2003: Hitoshi Okamura
[Molecular mechanisms of biological clock: from molecular rhythms to physiological rhythms].
Nō to shinkei = Brain and nerve 2003;55(1):5-11.
2003: MASATAKA NISHIMURA; K Yamagata; H Sugiura; Hitoshi Okamura
The activity-regulated cytoskeleton-associated (Arc) gene is a new light-inducible early gene in the mouse suprachiasmatic nucleus.
Neuroscience 2003;116(4):1141-7.
2002: Masahiko Kishimoto; Yasuhiko Okimura; Kazuhiro Yagita; Genzo Iguchi; Mariko Fumoto; Keiji Iida; Hiroshi Kaji; Hitoshi Okamura; Kazuo Chihara
Novel function of the transactivation domain of a pituitary-specific transcription factor, Pit-1.
The Journal of biological chemistry 2002;277(47):45141-8.
2002: Hitoshi Okamura; Shun Yamaguchi; Kazuhiro Yagita
Molecular machinery of the circadian clock in mammals.
Cell and tissue research 2002;309(1):47-56.
2002: Hiroyasu Onishi; Shun Yamaguchi; Kazuhiro Yagita; Yoshiki Ishida; Xin Dong; Hidehito Kimura; Zhang Jing; Hidefumi Ohara; Hitoshi Okamura
Rev-erbalpha gene expression in the mouse brain with special emphasis on its circadian profiles in the suprachiasmatic nucleus.
Journal of neuroscience research 2002;68(5):551-7.
2002: Yoshiki Ishida; Chihiro Yokoyama; Tsutomu Inatomi; Kazuhiro Yagita; Xin Dong; Lily Yan; Shun Yamaguchi; Ikuko Nagatsu; Takahide Komori; Kunio Kitahama; Hitoshi Okamura
Circadian rhythm of aromatic L-amino acid decarboxylase in the rat suprachiasmatic nucleus: gene expression and decarboxylating activity in clock oscillating cells.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(5):447-59.
2002: Lily Yan; Hitoshi Okamura
Gradients in the circadian expression of Per1 and Per2 genes in the rat suprachiasmatic nucleus.
The European journal of neuroscience 2002;15(7):1153-62.
2002: Kazuhiro Yagita; Filippo Tamanini; Maya Yasuda; Jan H J Hoeijmakers; Gijsbertus T J van der Horst; Hitoshi Okamura
Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein.
The EMBO journal 2002;21(6):1301-14.
2002: Yasuo Sumi; Kazuhiro Yagita; Shun Yamaguchi; Yoshiki Ishida; Yoshikazu Kuroda; Hitoshi Okamura
Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus.
Neuroscience letters 2002;320(1-2):13-6.
2002: Yasufumi Shigeyoshi; Elizabeth Meyer-Bernstein; Kazuhiro Yagita; Weili Fu; Yifeng Chen; Toru Takumi; Peter Schotland; Amita Sehgal; Hitoshi Okamura
Restoration of circadian behavioural rhythms in a period null Drosophila mutant (per01) by mammalian period homologues mPer1 and mPer2.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(2):163-71.
2001: Hidemi Nonaka; Noriaki Emoto; Koji Ikeda; Hiroyuki Fukuya; Mohammad Saifur Rohman; Sunu Budhi Raharjo; Kazuhiro Yagita; Hitoshi Okamura; Mitsuhiro Yokoyama
Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells.
Circulation 2001;104(15):1746-8.
2001: M Asai; Shun Yamaguchi; H Isejima; M Jonouchi; T Moriya; Shigenobu Shibata; Masaki Kobayashi; Hitoshi Okamura
Visualization of mPer1 transcription in vitro: NMDA induces a rapid phase shift of mPer1 gene in cultured SCN.
Current biology : CB 2001;11(19):1524-7.
2001: Yoshiki Ishida; Kazuhiro Yagita; T Fukuyama; MASATAKA NISHIMURA; M Nagano; Yasufumi Shigeyoshi; Shun Yamaguchi; Takahide Komori; Hitoshi Okamura
Constitutive expression and delayed light response of casein kinase Iepsilon and Idelta mRNAs in the mouse suprachiasmatic nucleus.
Journal of neuroscience research 2001;64(6):612-6.
2001: S Mitsui; Shun Yamaguchi; T Matsuo; Y Ishida; Hitoshi Okamura
Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism.
Genes & development 2001;15(8):995-1006.
2001: Kazuhiro Yagita; Filippo Tamanini; Gijsbertus T J van der Horst; Hitoshi Okamura
Molecular mechanisms of the biological clock in cultured fibroblasts.
Science (New York, N.Y.) 2001;292(5515):278-81.
2001: T Nakamura; Yasufumi Shigeyoshi; Y Maebayashi; Shun Yamaguchi; Kazuhiro Yagita; Hitoshi Okamura
Different developmental profiles of the expression of preprosomatostatin and preprotachykinin-A mRNAs in rat SCN neurons.
Brain research. Developmental brain research 2001;127(1):81-6.
2001: S Yamamoto; Yasufumi Shigeyoshi; Yoshiki Ishida; T Fukuyama; Shun Yamaguchi; Kazuhiro Yagita; T Moriya; Shigenobu Shibata; Naoyuki Takashima; Hitoshi Okamura
Expression of the Per1 gene in the hamster: brain atlas and circadian characteristics in the suprachiasmatic nucleus.
The Journal of comparative neurology 2001;430(4):518-32.
2001: Shun Yamaguchi; Masaki Kobayashi; Shigeru Mitsui; Yoshiki Ishida; Gijsbertus T J van der Horst; M Suzuki; Shigenobu Shibata; Hitoshi Okamura
View of a mouse clock gene ticking.
Nature 2001;409(6821):684.
2000: Shigeki Takekida; Lily Yan; Elizabeth S Maywood; Michael H Hastings; Hitoshi Okamura
Differential adrenergic regulation of the circadian expression of the clock genes Period1 and Period2 in the rat pineal gland.
The European journal of neuroscience 2000;12(12):4557-61.
2000: S Miyake; Yasuo Sumi; Lily Yan; Shigeki Takekida; T Fukuyama; Yoshiki Ishida; Shun Yamaguchi; Kazuhiro Yagita; Hitoshi Okamura
Phase-dependent responses of Per1 and Per2 genes to a light-stimulus in the suprachiasmatic nucleus of the rat.
Neuroscience letters 2000;294(1):41-4.
2000: Shun Yamaguchi; Shigeru Mitsui; S Miyake; Lily Yan; H Onishi; Kazuhiro Yagita; M Suzuki; Shigenobu Shibata; Masaki Kobayashi; Hitoshi Okamura
The 5' upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation.
Current biology : CB 2000;10(14):873-6.
2000: Shun Yamaguchi; Shigeru Mitsui; Lily Yan; Kazuhiro Yagita; S Miyake; Hitoshi Okamura
Role of DBP in the circadian oscillatory mechanism.
Molecular and cellular biology 2000;20(13):4773-81.
2000: Kazuhiro Yagita; Shun Yamaguchi; Filippo Tamanini; Gijsbertus T J van der Horst; Jan H J Hoeijmakers; Akira Yasui; Jennifer J Loros; Jay C Dunlap; Hitoshi Okamura
Dimerization and nuclear entry of mPER proteins in mammalian cells.
Genes & development 2000;14(11):1353-63.
2000: Lily Yan; S Miyake; Hitoshi Okamura
Distribution and circadian expression of dbp in SCN and extra-SCN areas in the mouse brain.
Journal of neuroscience research 2000;59(2):291-5.
1999: Hitoshi Okamura; S Miyake; Yasuo Sumi; Shun Yamaguchi; Akira Yasui; Manja Muijtjens; Jan H J Hoeijmakers; Gijsbertus T J van der Horst
Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock.
Science (New York, N.Y.) 1999;286(5449):2531-4.
1999: Y Maebayashi; Yasufumi Shigeyoshi; Toru Takumi; Hitoshi Okamura
A putative transcription factor with seven zinc-finger motifs identified in the developing suprachiasmatic nucleus by the differential display PCR method.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(22):10176-83.
1999: Lily Yan; Shigeki Takekida; Yasufumi Shigeyoshi; Hitoshi Okamura
Per1 and Per2 gene expression in the rat suprachiasmatic nucleus: circadian profile and the compartment-specific response to light.
Neuroscience 1999;94(1):141-50.
1999: Toru Takumi; Y Nagamine; S Miyake; C Matsubara; K Taguchi; Shigeki Takekida; Yoko Sakakida; K Nishikawa; T Kishimoto; S Niwa; K Okumura; Hitoshi Okamura
A mammalian ortholog of Drosophila timeless, highly expressed in SCN and retina, forms a complex with mPER1.
Genes to cells : devoted to molecular & cellular mechanisms 1999;4(1):67-75.
1998: Toru Takumi; K Taguchi; S Miyake; Yoko Sakakida; Naoyuki Takashima; C Matsubara; Y Maebayashi; K Okumura; Shigeki Takekida; S Yamamoto; Kazuhiro Yagita; L Yan; M W Young; Hitoshi Okamura
A light-independent oscillatory gene mPer3 in mouse SCN and OVLT.
The EMBO journal 1998;17(16):4753-9.
1998: Toru Takumi; C Matsubara; Yasufumi Shigeyoshi; K Taguchi; Kazuhiro Yagita; Y Maebayashi; Yoko Sakakida; K Okumura; Naoyuki Takashima; Hitoshi Okamura
A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(3):167-76.
1997: Yasufumi Shigeyoshi; Y Maebayashi; Hitoshi Okamura
Co-localization of preprosomatostatin mRNA and preprotachykinin A mRNA in neurons of the rat suprachiasmatic nucleus.
Brain research. Molecular brain research 1997;48(1):159-63.
1997: Yasufumi Shigeyoshi; T Ogura; H Esumi; Kazuo Chihara; Yasuhiko Ibata; Hitoshi Okamura
Lesion-induced neuronal nitric oxide synthase in Purkinje cells of the rat cerebellar cortex: histochemical and in situ hybridization study.
Brain research. Molecular brain research 1997;44(2):229-37.
1997: Hitoshi Okamura; T Murakami; C Yokoyama; T Nakamura; Yasuhiko Ibata
Self-injurious behavior and dopaminergic neuron system in neonatal 6-hydroxydopamine-lesioned rat: 2. Intracerebral microinjection of dopamine agonists and antagonists.
The Journal of pharmacology and experimental therapeutics 1997;280(2):1031-7.
1997: C Yokoyama; Hitoshi Okamura
Self-injurious behavior and dopaminergic neuron system in neonatal 6-hydroxydopamine-lesioned rat: 1. Dopaminergic neurons and receptors.
The Journal of pharmacology and experimental therapeutics 1997;280(2):1016-30.
1996: Yasuo Hisa; Toshiyuki Uno; N Tadaki; Shinobu Koike; H Banba; M Tanaka; Hitoshi Okamura; Yasuhiko Ibata
Relationship of neuropeptides to nitrergic innervation of the canine laryngeal glands.
Regulatory peptides 1996;66(3):197-201.
1996: Shigeji Matsumoto; Hitoshi Okamura; K Suzuki; N Sugai; T Shimizu
Inhibitory mechanism of CO2 inhalation on slowly adapting pulmonary stretch receptors in the anesthetized rabbit.
The Journal of pharmacology and experimental therapeutics 1996;279(1):402-9.
1996: Masaki Tanaka; Hitoshi Okamura; T Matsuda; Yasufumi Shigeyoshi; Yasuo Hisa; K Chihara; Yasuhiko Ibata
Somatostatin neurons form a distinct peptidergic neuronal group in the rat suprachiasmatic nucleus: a double labeling in situ hybridization study.
Neuroscience letters 1996;215(2):119-22.
1996: Yasuo Hisa; N Tadaki; Toshiyuki Uno; Shinobu Koike; M Tanaka; Hitoshi Okamura; Yasuhiko Ibata
Nitrergic innervation of the rat larynx measured by nitric oxide synthase immunohistochemistry and NADPH-diaphorase histochemistry.
The Annals of otology, rhinology, and laryngology 1996;105(7):550-4.
1996: Toshiyuki Uno; Yasuo Hisa; N Tadaki; Hitoshi Okamura; Yasuhiko Ibata
Tyrosine hydroxylase-immunoreactive cells in the nodose ganglion for the canine larynx.
Neuroreport 1996;7(8):1373-6.
1996: Hitoshi Okamura; T Sugano; Y Ibata
Reserpine-induced immunocytochemical change of neuropeptide Y in the hypothalamic arcuate nucleus.
Neurochemical research 1996;21(2):239-43.
1996: Yasuo Hisa; Shinobu Koike; Toshiyuki Uno; N Tadaki; M Tanaka; Hitoshi Okamura; Yasuhiko Ibata
Nitrergic neurons in the canine intrinsic laryngeal muscle.
Neuroscience letters 1996;203(1):45-8.
1995: N Tadaki; Yasuo Hisa; Toshiyuki Uno; Shinobu Koike; Hitoshi Okamura; Yasuhiko Ibata
Neurotransmitters for the canine inferior pharyngeal constrictor muscle.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1995;113(6):755-9.
1995: Hitoshi Okamura; C Yokoyama; Y Ibata
Lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity.
Experimental neurology 1995;136(2):136-42.
1995: T Nishiwaki; Hitoshi Okamura; K Kanemasa; T Inatomi; Yasuhiko Ibata; Chiaki Fukuhara; S T Inouye
Differences of somatostatin mRNA in the rat suprachiasmatic nucleus under light-dark and constant dark conditions: an analysis by in situ hybridization.
Neuroscience letters 1995;197(3):231-4.
1995: C Yokoyama; Hitoshi Okamura; Yasuhiko Ibata
Dopamine D2-like receptors labeled by [3H]YM-09151-2 in the rat hippocampus: characterization and autoradiographic distribution.
Brain research 1995;681(1-2):153-9.
1995: Hitoshi Okamura; Masaki Tanaka; K Kanemasa; Y Ban; S T Inouye; Yasuhiko Ibata
In situ hybridization histochemistry of vgf mRNA in the rat suprachiasmatic nucleus: co-localization with vasopressin/neurophysin and VIP/PHI.
Neuroscience letters 1995;189(1):181-4a.
1995: Hitoshi Okamura; F Kawakami; Y Tamada; M Geffard; T Nishiwaki; Yasuhiko Ibata; S T Inouye
Circadian change of VIP mRNA in the rat suprachiasmatic nucleus following p-chlorophenylalanine (PCPA) treatment in constant darkness.
Brain research. Molecular brain research 1995;29(2):358-64.
1995: Yasuo Hisa; Toshiyuki Uno; N Tadaki; K Umehara; Hitoshi Okamura; Yasuhiko Ibata
NADPH-diaphorase and nitric oxide synthase in the canine superior cervical ganglion.
Cell and tissue research 1995;279(3):629-31.
1995: Hitoshi Okamura; K Umehara; N Tadaki; Yasuo Hisa; H Esumi; Yasuhiko Ibata
Sympathetic preganglionic neurons contain nitric oxide synthase and project to the superior cervical ganglion: combined application of retrograde neuronal tracer and NADPH-diaphorase histochemistry.
Brain research bulletin 1995;36(5):491-4.
1994: K Yagita; Hitoshi Okamura; Yasuhiko Ibata
Rehydration process from salt-loading: recovery of vasopressin and its coexisting galanin, dynorphin and tyrosine hydroxylase immunoreactivities in the supraoptic and paraventricular nuclei.
Brain research 1994;667(1):13-23.
1994: Hitoshi Okamura; Masaki Tanaka; K Kanemasa; Y Ban; S I Inouye; Yasuhiko Ibata
In situ hybridization histochemistry of vghm1f mRNA in the rat suprachiasmatic nucleus: co-localization with vasopressin/neurophysin and VIP/PHI.
Neuroscience letters 1994;182(2):181-4.
1994: Hitoshi Okamura; Yasuhiko Ibata
GRP immunoreactivity shows a day-night difference in the suprachiasmatic nuclear soma and efferent fibers: comparison to VIP immunoreactivity.
Neuroscience letters 1994;181(1-2):165-8.
1994: Y Tamada; Masaki Tanaka; Y Ichitani; Hitoshi Okamura; N Yanaihara; Yasuhiko Ibata
Pituitary adenylate cyclase-activating polypeptide (PACAP)-like immunoreactive neuronal elements in rat hypothalamus and median eminence with special reference to morphological background of its effect on anterior pituitary--light and electron microscopic immunocytochemistry.
Neuroscience letters 1994;180(2):105-8.
1994: Yasuo Hisa; N Tadaki; Toshiyuki Uno; Hitoshi Okamura; J Taguchi; Yasuhiko Ibata
Neuropeptide participation in canine laryngeal sensory innervation. Immunohistochemistry and retrograde labeling.
The Annals of otology, rhinology, and laryngology 1994;103(10):767-70.
1994: Yasuo Hisa; N Tadaki; Toshiyuki Uno; Hitoshi Okamura; J Taguchi; Yasuhiko Ibata
Calcitonin gene-related peptide-like immunoreactive motoneurons innervating the canine inferior pharyngeal constrictor muscle.
Acta oto-laryngologica 1994;114(5):560-4.
1994: Hitoshi Okamura; A Miyagawa; H Takagi; H Esumi; N Yanaihara; Yasuhiko Ibata
Co-existence of PACAP and nitric oxide synthase in the rat hypothalamus.
Neuroreport 1994;5(10):1177-80.
1994: F R Cagampang; Hitoshi Okamura; S Inouye
Circadian rhythms of norepinephrine in the rat suprachiasmatic nucleus.
Neuroscience letters 1994;173(1-2):185-8.
1994: A Miyagawa; Hitoshi Okamura; Yasuhiko Ibata
Coexistence of oxytocin and NADPH-diaphorase in magnocellular neurons of the paraventricular and the supraoptic nuclei of the rat hypothalamus.
Neuroscience letters 1994;171(1-2):13-6.
1994: Yasufumi Shigeyoshi; Hitoshi Okamura; T Inatomi; Toshimitsu Matsui; M Ito; Hiroshi Kaji; H Abe; H Nakata; Tsutomu Chiba; Kazuo Chihara
Distribution of mRNA for CCK-B receptor in the brain of Mastomys natalensis: abundant expression in telencephalic neurons.
Brain research 1994;640(1-2):81-92.
1994: Masaki Tanaka; Hitoshi Okamura; Y Tamada; I Nagatsu; Yoshifumi Tanaka; Yasuhiko Ibata
Catecholaminergic input to spinally projecting serotonin neurons in the rostral ventromedial medulla oblongata of the rat.
Brain research bulletin 1994;35(1):23-30.
1994: K Tominaga; Hitoshi Okamura; S T Inouye
Organotypic slice culture of the suprachiasmatic nucleus.
Neuroscience and biobehavioral reviews 1994;18(4):601-4.
1993: Y Otori; K Tominaga; Chiaki Fukuhara; J Yang; S Yamazaki; F R Cagampang; Hitoshi Okamura; S T Inouye
Substance P-like immunoreactivity in the suprachiasmatic nucleus of the rat.
Brain research 1993;619(1-2):271-7.
1993: Yasuhiko Ibata; Masaki Tanaka; Y Ichitani; Y Takahashi; Hitoshi Okamura
Neuronal interaction between VIP and vasopressin neurones in the rat suprachiasmatic nucleus.
Neuroreport 1993;4(2):128-30.
1993: Masaki Tanaka; Y Ichitani; Hitoshi Okamura; Yoshifumi Tanaka; Yasuhiko Ibata
The direct retinal projection to VIP neuronal elements in the rat SCN.
Brain research bulletin 1993;31(6):637-40.
1993: Masaki Tanaka; Hitoshi Okamura; N Yanaihara; Yoshifumi Tanaka; Yasuhiko Ibata
Differential expression of serotonin and [Met]enkephalin-Arg6-Gly7-Leu8 in neurons of the rat brain stem.
Brain research bulletin 1993;30(5-6):561-70.
1992: Yasuo Hisa; Toshiyuki Uno; N Tadaki; Y Murakami; Hitoshi Okamura; Yasuhiko Ibata
Distribution of calcitonin gene-related peptide nerve fibers in the canine larynx.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 1992;249(1):52-5.
1992: Toshiyuki Uno; Yasuo Hisa; Y Murakami; Hitoshi Okamura; Yasuhiko Ibata
Distribution of tyrosine hydroxylase immunoreactive nerve fibers in the canine larynx.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 1992;249(1):40-3.
1991: Y Ichitani; Hitoshi Okamura; Y Matsumoto; I Nagatsu; Yasuhiko Ibata
Degeneration of the nigral dopamine neurons after 6-hydroxydopamine injection into the rat striatum.
Brain research 1991;549(2):350-3.
1990: J Abe; Hitoshi Okamura; Yasuhiko Ibata; A Motoyama; I Wakabayashi; N Ling; Willis Paull
Immunocytochemical demonstration of GAP-like immunoreactive neuronal elements in the human hypothalamus and pituitary.
Histochemistry 1990;94(2):127-33.
1989: S Murakami; Hitoshi Okamura; G Pelletier; Yasuhiko Ibata
Differential colocalization of neuropeptide Y- and methionine-enkephalin-Arg6-Gly7-Leu8-like immunoreactivity in catecholaminergic neurons in the rat brain stem.
The Journal of comparative neurology 1989;281(4):532-44.
1989: Yasuhiko Ibata; Y Takahashi; Hitoshi Okamura; F Kawakami; H Terubayashi; T Kubo; N Yanaihara
Vasoactive intestinal peptide (VIP)-like immunoreactive neurons located in the rat suprachiasmatic nucleus receive a direct retinal projection.
Neuroscience letters 1989;97(1-2):1-5.
1989: T Ibuki; Hitoshi Okamura; M Miyazaki; N Yanaihara; E A Zimmerman; Yasuhiko Ibata
Comparative distribution of three opioid systems in the lower brainstem of the monkey (Macaca fuscata).
The Journal of comparative neurology 1989;279(3):445-56.
1989: Hitoshi Okamura; S Murakami; N Yanaihara; Yasuhiko Ibata
Coexistence of catecholamine and methionine enkephalin-Arg6-Gly7-Leu8 in neurons of the rat ventrolateral medulla oblongata. Application of combined peptide immunocytochemistry and histofluorescence method in the same vibratome section.
Histochemistry 1989;91(1):31-4.
1988: Hitoshi Okamura; K Kitahama; N Mons; Yasuhiko Ibata; M Jouvet; M Geffard
L-dopa-immunoreactive neurons in the rat hypothalamic tuberal region.
Neuroscience letters 1988;95(1-3):42-6.
1988: J Abe; Hitoshi Okamura; T Kitamura; Yasuhiko Ibata; N Minamino; H Matsuo; Willis Paull
Immunocytochemical demonstration of dynorphin(PH-8P)-like immunoreactive elements in the human hypothalamus.
The Journal of comparative neurology 1988;276(4):508-13.
1988: T Ibuki; Hitoshi Okamura; M Miyazaki; H Kimura; N Yanaihara; Yasuhiko Ibata
Colocalization of GABA and [Met]enkephalin-Arg6-Gly7-Leu8 in the rat cerebellum.
Neuroscience letters 1988;91(2):131-5.
1988: Yasuhiko Ibata; Y Takahashi; Hitoshi Okamura; T Kubo; F Kawakami
Fine structure of NPY-containing neurons in the lateral geniculate nucleus and their terminals in the suprachiasmatic nucleus of the rat.
Brain research 1988;439(1-2):230-5.
1987: J Abe; Hitoshi Okamura; S Makino; N Yanaihara; Yasuhiko Ibata
Immunocytochemical distribution of [Met]enkephalin-Arg-Gly-Leu immunoreactivity in the rat diencephalon.
Brain research bulletin 1987;19(6):735-41.
1985: Yasuhiko Ibata; F Kawakami; Hitoshi Okamura; H L Obata-Tsuto; N Morimoto; E A Zimmerman
Light and electron microscopic immunocytochemistry of beta-endorphin/beta-LPH-like immunoreactive neurons in the arcuate nucleus and surrounding areas of the rat hypothalamus.
Brain research 1985;341(2):233-42.
1985: T Tsuto; Hitoshi Okamura; K Fukui; H L Obata-Tsuto; H Terubayashi; J Yanagihara; Naomi Iwai; S Majima; N Yanaihara; Yasuhiko Ibata
Immunohistochemical investigations of gut hormones in the colon of patients with Hirschsprung's disease.
Journal of pediatric surgery 1985;20(3):266-70.
1984: Yasuhiko Ibata; F Kawakami; K Fukui; H L Obata-Tsuto; M Tanaka; T Kubo; Hitoshi Okamura; N Morimoto; C Yanaihara; N Yanaihara
Light and electron microscopic immunocytochemistry of neurotensin-like immunoreactive neurons in the rat hypothalamus.
Brain research 1984;302(2):221-30.
1984: H L Obata-Tsuto; T Tsuto; Hitoshi Okamura; T Kubo; F Fukui; N Yanaihara; Yasuhiko Ibata
The fine structures of the VIP-like immunoreactive neurons in the cat hypothalamus.
Brain research bulletin 1984;12(3):315-21.
1984: Yasuhiko Ibata; F Kawakami; K Fukui; Hitoshi Okamura; H L Obata-Tsuto; T Tsuto; H Terubayashi
Morphological survey of neurotensin-like immunoreactive neurons in the hypothalamus.
Peptides 1984;5 Suppl 1():109-20.
1983: H L Obata-Tsuto; Hitoshi Okamura; T Tsuto; H Terubayashi; K Fukui; N Yanaihara; Yasuhiko Ibata
Distribution of the VIP-like immunoreactive neurons in the cat central nervous system.
Brain research bulletin 1983;10(5):653-60.