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Tomio Okamura

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Living Beings

Dogs
Macaca

Chemicals & Drugs

Physiology

Disorders

Anatomy

Procedures

Electric Stimulation

Concepts & Ideas

Drug Dose-Response Relationship

Phenomena

Muscle Contraction

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Co-Publications
Name
142
Toda, Noboru
70
Ayajiki, Kazuhide
20
Fujioka, Hideyuki
17
Shinozaki, Kazuya
11
Kashiwagi, Atsunori
9
Toda, M
8
Masada, Masahiro
7
Nishio, Yoshihiko
6
Uchiyama, M
5
Yoshida, Yuichi
5
Kikkawa, Ryuichi
4
Hayashida, H
3
Tanaka, T
3
Toda, N
3
Kimura, Toshio

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Publications

TOP 3
Ayajiki Kazuhide; Ozeki Yasushi; Wang Chunmei; Okamura Tomio
Cilostazol's effect on the response to perivascular nerve stimulation in isolated dog cerebral and mesenteric arteries.
Ayajiki Kazuhide; Kimura Toshio; Yamamizu Kohei; Okamura Tomio
Mechanisms underlying mechanical responses to Ephedra herb of isolated rabbit urinary bladder and urethra, a possible stress urinary incontinence therapeutic.
Yamamizu Kohei; Shinozaki Kazuya; Ayajiki Kazuhide; Gemba Munekazu; Okamura Tomio
Oral administration of both tetrahydrobiopterin and L-arginine prevents endothelial dysfunction in rats with chronic renal failure.

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All Publications

2008: Ayajiki Kazuhide; Ozeki Yasushi; Wang Chunmei; Okamura Tomio
Cilostazol's effect on the response to perivascular nerve stimulation in isolated dog cerebral and mesenteric arteries.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(7):1425-33.
2008: Ayajiki Kazuhide; Kimura Toshio; Yamamizu Kohei; Okamura Tomio
Mechanisms underlying mechanical responses to Ephedra herb of isolated rabbit urinary bladder and urethra, a possible stress urinary incontinence therapeutic.
Journal of pharmacological sciences 2008;107(2):175-80.
2007: Yamamizu Kohei; Shinozaki Kazuya; Ayajiki Kazuhide; Gemba Munekazu; Okamura Tomio
Oral administration of both tetrahydrobiopterin and L-arginine prevents endothelial dysfunction in rats with chronic renal failure.
Journal of cardiovascular pharmacology 2007;49(3):131-9.
2007: Shinozaki Kazuya; Nishio Yoshihiko; Ayajiki Kazuhide; Yoshida Yuichi; Masada Masahiro; Kashiwagi Atsunori; Okamura Tomio
Pitavastatin restores vascular dysfunction in insulin-resistant state by inhibiting NAD(P)H oxidase activity and uncoupled endothelial nitric oxide synthase-dependent superoxide production.
Journal of cardiovascular pharmacology 2007;49(3):122-30.
2007: Toda Noboru; Ayajiki Kazuhide; Okamura Tomio
Interaction of endothelial nitric oxide and angiotensin in the circulation.
Pharmacological reviews 2007;59(1):54-87.
2006: Okamura Tomio
[EDRF]
Nippon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 5():244-8.
2005: Shinozaki Kazuya; Nishio Yoshihiko; Yoshida Yuichi; Koya Daisuke; Ayajiki Kazuhide; Masada Masahiro; Kashiwagi Atsunori; Okamura Tomio
Supplement of tetrahydrobiopterin by a gene transfer of GTP cyclohydrolase I cDNA improves vascular dysfunction in insulin-resistant rats.
Journal of cardiovascular pharmacology 2005;46(4):505-12.
2005: Toda Noboru; Ayajiki Kazuhede; Okamura Tomio
Nitric oxide and penile erectile function.
Pharmacology & therapeutics 2005;106(2):233-66.
2005: Ayajiki Kazuhide; Fujioka Hideyuki; Shinozaki Kazuya; Okamura Tomio
Effects of capsaicin and nitric oxide synthase inhibitor on increase in cerebral blood flow induced by sensory and parasympathetic nerve stimulation in the rat.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;98(5):1792-8.
2004: Shinozaki Kazuya; Ayajiki Kazuhide; Kashiwagi Atsunori; Masada Masahiro; Okamura Tomio
Malfunction of vascular control in lifestyle-related diseases: mechanisms underlying endothelial dysfunction in the insulin-resistant state.
Journal of pharmacological sciences 2004;96(4):401-5.
2004: Okamura Tomio
[Gene, regulation of synthesis, and physiological activity of nNOS]
Nippon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():455-9.
2004: Ayajiki Kazuhide; Shinozaki Kazuya; Okamura Tomio
[Mechanisms of nitric oxide production]
Nippon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():446-50.
2004: Shinozaki Kazuya; Kashiwagi Atsunori; Masada Masahiro; Okamura Tomio
Molecular mechanisms of impaired endothelial function associated with insulin resistance.
Current drug targets. Cardiovascular & haematological disorders 2004;4(1):1-11.
2004: Fujioka Hideyuki; Ayajiki Kazuhide; Shinozaki Kazuya; Okamura Tomio
Mechanisms underlying endothelium-dependent flow increase in perfused rat mesenteric vascular bed.
European journal of pharmacology 2004;485(1-3):219-25.
2004: Shinozaki Kazuya; Ayajiki Kazuhide; Nishio Yoshihiko; Sugaya Takeshi; Kashiwagi Atsunori; Okamura Tomio
Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance.
Hypertension 2004;43(2):255-62.
2003: Tanaka Toshiki; Ayajiki Kazuhide; Fujioka Hideyuki; Toda Noboru; Okamura Tomio
Protection by hypothermia of hypoxia-induced inhibition of neurogenic vasodilation in porcine cerebral arteries.
Journal of pharmacological sciences 2003;92(2):93-9.
2003: Shinozaki Kazuya; Kashiwagi Atsunori; Masada Masahiro; Okamura Tomio
Stress and vascular responses: oxidative stress and endothelial dysfunction in the insulin-resistant state.
Journal of pharmacological sciences 2003;91(3):187-91.
2003: Ayajiki Kazuhide; Fujioka Hideyuki; Toda Noboru; Okada Shigeru; Minamiyama Yukiko; Imaoka Susumu; Funae Yoshihiko; Watanabe Shuji; Nakamura Akio; Okamura Tomio
Mediation of arachidonic acid metabolite(s) produced by endothelial cytochrome P-450 3A4 in monkey arterial relaxation.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(3):237-43.
2002: Fujioka Hideyuki; Ayajiki Kazuhide; Shinozaki Kazuya; Toda Noboru; Okamura Tomio
Mechanisms underlying endothelium-dependent, nitric oxide- and prostanoid-independent relaxation in monkey and dog coronary arteries.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(5):488-95.
2002: Ayajiki Kazuhide; Fujioka Hideyuki; Torii Ryuzo; Toda Noboru; Okamura Tomio
Endothelial and neuronal functions in cerebral and temporal arteries from monkeys fed a high-cholesterol diet.
Journal of cardiovascular pharmacology 2002;40(3):456-66.
2002: Ayajiki Kazuhide; Okamura Tomio; Noda Kumiko; Toda Noboru
Functional study on nitroxidergic nerve in isolated dog pulmonary arteries and veins.
Japanese journal of pharmacology 2002;89(2):197-200.
2002: Kimura Toshio; Ayajiki Kazuhide; Noda Yoichi; Okamura Tomio
Comparison of the responses to thrombin in monkey renal and uterine arteries.
Journal of the Society for Gynecologic Investigation 2002;9(3):146-51.
2002: Okamura Tomio; Fujioka Hideyuki; Ayajiki Kazuhide
Effects of nipradilol on alpha-adrenoceptor function in ocular arteries.
Pharmacology 2002;65(2):110-8.
2002: Ayajiki Kazuhide; Toda Noboru; Okamura Tomio
[Nitroxidergic (nitrergic) nerve and erectile dysfunction]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 2002;119(1):21-8.
2002: Okamura Tomio; Ayajiki Kazuhide; Fujioka Hideyuki; Shinozaki Kazuya; Toda Noboru
Neurogenic cerebral vasodilation mediated by nitric oxide.
Japanese journal of pharmacology 2002;88(1):32-8.
2001: Shinozaki K; Hirayama A; Nishio Y; Yoshida Y; Ohtani T; Okamura T; Masada M; Kikkawa R; Kodama K; Kashiwagi A
Coronary endothelial dysfunction in the insulin-resistant state is linked to abnormal pteridine metabolism and vascular oxidative stress.
Journal of the American College of Cardiology 2001;38(7):1821-8.
2001: Okamura T; Fujioka H; Ayajiki K
Effects of calcium antagonists on the nitrergic nerve function in canine corpus cavernosum.
Japanese journal of pharmacology 2001;87(3):208-13.
2001: Ayajiki K; Fujioka H; Okamura T; Toda N
Relatively selective neuronal nitric oxide synthase inhibition by 7-nitroindazole in monkey isolated cerebral arteries.
European journal of pharmacology 2001;423(2-3):179-83.
2001: Toda N; Ayajiki K; Fujioka H; Okamura T
Ginsenoside potentiates NO-mediated neurogenic vasodilatation of monkey cerebral arteries.
Journal of ethnopharmacology 2001;76(1):109-13.
2001: Ayajiki K; Fujioka H; Noda K; Okamura T; Toda N
Modifications by sumatriptan and acetylcholine of nitric oxide-mediated neurogenic dilatation in dog cerebral arteries.
European journal of pharmacology 2001;420(1):67-72.
2001: Kimura T; Toda N; Noda Y; Okamura T
Mechanisms of relaxation induced by angiotensin II in isolated canine and human uterine arteries.
Journal of cardiovascular pharmacology 2001;37(5):585-95.
2001: Kadowaki T; Okamura T; Ueshima H
[Lipid disorder and atherosclerosis caused by smoking]
Nippon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 3():214-9.
2001: Okamura T; Ayajiki K; Toda N
Hypothermia on NO-mediated neurogenic relaxation and on hypoxic inhibition in the response of canine cerebral arteries.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(1):47-53.
2000: Ayajiki K; Fujioka H; Okamura T
Mechanisms underlying endothelium-dependent, nitric oxide/prostacyclin-independent, acetylcholine-induced relaxation in canine corpus cavernosum.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(4-5):448-51.
2000: Okamura T; Ghoneim H A; Ayajiki K; Ammar E S; Toda N
Mechanisms underlying contraction and relaxation induced by nerve stimulation in monkey uterine arteries.
Pharmacology 2000;61(4):251-6.
2000: Ayajiki K; Ozaki M; Shiomi M; Okamura T; Toda N
Comparison of endothelium-dependent relaxation in carotid arteries from Japanese white and Watanabe heritable hyperlipidemic rabbits.
Journal of cardiovascular pharmacology 2000;36(5):622-30.
2000: Ayajiki K; Tanaka T; Okamura T; Toda N
Evidence for nitroxidergic innervation in monkey ophthalmic arteries in vivo and in vitro.
American journal of physiology. Heart and circulatory physiology 2000;279(4):H2006-12.
2000: Shinozaki K; Nishio Y; Okamura T; Yoshida Y; Maegawa H; Kojima H; Masada M; Toda N; Kikkawa R; Kashiwagi A
Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats.
Circulation research 2000;87(7):566-73.
2000: Toda N; Ayajiki K; Tanaka T; Okamura T
Preganglionic and postganglionic neurons responsible for cerebral vasodilation mediated by nitric oxide in anesthetized dogs.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(4):700-8.
2000: Shinozaki K; Okamura T; Nishio Y; Kashiwagi A; Kikkawa R; Toda N
Evaluation of endothelial free radical release by vascular tension responses in insulin-resistant rat aorta.
European journal of pharmacology 2000;394(2-3):295-9.
2000: Toda N; Tanaka T; Ayajiki K; Okamura T
Cerebral vasodilatation induced by stimulation of the pterygopalatine ganglion and greater petrosal nerve in anesthetized monkeys.
Neuroscience 2000;96(2):393-8.
1999: Fujioka H; Okamura T; Toda N
Inhibition by adrenomedullin of amine release from adrenergic nerves in dog mesenteric arteries.
European journal of pharmacology 1999;385(2-3):155-61.
1999: Shinozaki K; Kashiwagi A; Nishio Y; Okamura T; Yoshida Y; Masada M; Toda N; Kikkawa R
Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta.
Diabetes 1999;48(12):2437-45.
1999: Ayajiki K; Okamura T; Fujioka H; Imaoka S; Funae Y; Toda N
Involvement of CYP3A-derived arachidonic acid metabolite(s) in responses to endothelium-derived K+ channel opening substance in monkey lingual artery.
British journal of pharmacology 1999;128(3):802-8.
1999: Kashiwagi A; Shinozaki K; Nishio Y; Okamura T; Toda N; Kikkawa R
Free radical production in endothelial cells as a pathogenetic factor for vascular dysfunction in the insulin resistance state.
Diabetes research and clinical practice 1999;45(2-3):199-203.
1999: Toda M; Okamura T; Ayajiki K; Toda N
Neurogenic vasoconstriction as affected by cholinergic and nitroxidergic nerves in dog ciliary and ophthalmic arteries.
Investigative ophthalmology & visual science 1999;40(8):1753-60.
1999: Okamura T; Ayajiki K; Fujioka H; Toda M; Fujimiya M; Toda N
Effects of endothelial impairment by saponin on the responses to vasodilators and nitrergic nerve stimulation in isolated canine corpus cavernosum.
British journal of pharmacology 1999;127(3):802-8.
1999: Okamura T; Ayajiki K; Fujioka H; Toda N
Mechanisms underlying arginine vasopressin-induced relaxation in monkey isolated coronary arteries.
Journal of hypertension 1999;17(5):673-8.
1999: Ayajiki K; Hayashida H; Okamura T; Toda N
Influence of denervation on neurogenic inhibitory response of corpus cavernosum and nitric oxide synthase histochemistry.
Brain research 1999;825(1-2):14-21.
1999: Toda M; Okamura T; Fujimiya M; Azuma I; Toda N
Mechanisms underlying the neurogenic relaxation of isolated porcine sphincter pupillae.
Experimental eye research 1999;68(4):505-12.
1999: Okamura T; Ayajiki K; Uchiyama M; Uehara M; Toda N
Neurogenic vasodilatation of canine isolated small labial arteries.
The Journal of pharmacology and experimental therapeutics 1999;288(3):1031-6.
1999: Tanaka T; Okamura T; Handa J; Toda N
Neurogenic vasodilation mediated by nitric oxide in porcine cerebral arteries.
Journal of cardiovascular pharmacology 1999;33(1):56-64.
1998: Ayajiki K; Okamura T; Fujioka H; Nakayama K; Tsuji K; Toda N
Functional studies on blockade by neosurugatoxin of nicotinic receptors in nitroxidergic and sensory nerve terminals and intramural ganglionic cells.
Japanese journal of pharmacology 1998;78(2):217-23.
1998: Okamura T; Tanobe Y; Fujioka H; Ayajiki K; Toda N
Mechanism of neurogenic relaxation and modification of the response by enteric substances in isolated dog colon.
European journal of pharmacology 1998;358(3):245-52.
1998: Okamura T; Fujioka H; Ayajiki K; Toda N
Modifications by superoxide-generating agent, neurotransmitters and neuromodulators of nitroxidergic nerve function in monkey cerebral arteries.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1321-5.
1998: Okamura T; Ayajiki K; Uchiyama M; Kagami K; Toda N
Mechanisms underlying constrictor and dilator responses to perivascular nerve stimulation in canine lingual arteries.
European journal of pharmacology 1998;354(1):43-50.
1998: Toda N; Toda M; Ayajiki K; Okamura T
Cholinergic nerve function in monkey ciliary arteries innervated by nitroxidergic nerve.
The American journal of physiology 1998;274(5 Pt 2):H1582-9.
1998: Toda N; Okamura T
Cerebral vasodilators.
Japanese journal of pharmacology 1998;76(4):349-67.
1998: Okamura T; Ayajiki K; Toda N
Monkey corpus cavernosum relaxation mediated by NO and other relaxing factor derived from nerves.
The American journal of physiology 1998;274(4 Pt 2):H1075-81.
1998: Toda M; Ayajiki K; Okamura T; Azuma I; Toda N
Desmopressin-induced dog ciliary artery relaxation.
European journal of pharmacology 1998;344(2-3):197-201.
1998: Shiraishi S; Okamura T; Kodama M; Toda N
Mechanisms underlying the neurogenic relaxation in dog isolated hepatic arteries.
Journal of cardiovascular pharmacology 1998;31(3):372-6.
1998: Sai Y; Ayajiki K; Okamura T; Nosaka S; Toda N
Comparison of the effects of pancuronium and vecuronium in canine coronary and renal arteries.
Anesthesiology 1998;88(1):165-71.
1997: Toda N; Ayajiki K; Okamura T
Effect of Ca2+/calmodulin-dependent protein kinase II inhibitors on the neurogenic cerebroarterial relaxation.
European journal of pharmacology 1997;340(1):59-65.
1997: Okamura T; Toda M; Ayajiki K; Toda N
Receptor subtypes involved in relaxation and contraction by arginine vasopressin in canine isolated short posterior ciliary arteries.
Journal of vascular research 1997;34(6):464-72.
1997: Ayajiki K; Hayashida H; Okamura T; Toda N
Pelvic nerve stimulation-induced pressor responses in corpus cavernosum of anesthetized dogs.
The American journal of physiology 1997;273(5 Pt 2):H2141-5.
1997: Toda M; Okamura T; Azuma I; Toda N
Modulation by neurogenic acetylcholine of nitroxidergic nerve function in porcine ciliary arteries.
Investigative ophthalmology & visual science 1997;38(11):2261-9.
1997: Okamura T; Ayajiki K; Toda N
Hypoxia-induced inhibition of the response to nitroxidergic nerve stimulation in canine cerebral arteries.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(7):807-13.
1997: Zhang J X; Okamura T; Toda N
Prejunctional regulation by endogenous and exogenous acetylcholine of adrenergic nerve function in isolated canine mesenteric arteries.
Hypertension research : official journal of the Japanese Society of Hypertension 1997;20(2):119-25.
1997: Ayajiki K; Okamura T; Toda N
Flunarizine, an anti-migraine agent, impairs nitroxidergic nerve function in cerebral arteries.
European journal of pharmacology 1997;329(1):49-53.
1997: Toda N; Ayajiki K; Uchiyama M; Okamura T
Nitric oxide-mediated neurogenic vasodilatation in isolated monkey lingual arteries.
The American journal of physiology 1997;272(4 Pt 2):H1582-8.
1997: Okamura T; Zhang J X; Kangawa K; Toda N
Inhibition by adrenomedullin of the adrenergic neurogenic response in canine mesenteric arteries.
Japanese journal of pharmacology 1997;73(3):259-61.
1997: Uchiyama M; Okamura T; Uehara M; Toda N
Analysis of the vasodilator nerve function by nicotine in isolated dog skin artery.
European journal of pharmacology 1997;321(1):19-25.
1997: Toda N; Ayajiki K; Okamura T
Inhibition of nitroxidergic nerve function by neurogenic acetylcholine in monkey cerebral arteries.
The Journal of physiology 1997;498 ( Pt 2)():453-61.
1997: Shiraishi S; Okamura T; Toda N
beta1-Adrenoceptor-mediated relaxation by norepinephrine in dog hepatic arteries.
Japanese journal of pharmacology 1997;73(1):101-3.
1997: Okamura T; Ayajiki K; Kangawa K; Toda N
Mechanism of adrenomedullin-induced relaxation in isolated canine retinal arteries.
Investigative ophthalmology & visual science 1997;38(1):56-61.
1996: Okamura T; Kitamura Y; Uchiyama M; Toda M; Ayajiki K; Toda N
Canine retinal arterial and arteriolar dilatation induced by nipradilol, a possible glaucoma therapeutic.
Pharmacology 1996;53(5):302-10.
1996: Hayashida H; Fujimoto H; Yoshida K; Tomoyoshi T; Okamura T; Toda N
Comparison of neurogenic contraction and relaxation in canine corpus cavernosum and penile artery and vein.
Japanese journal of pharmacology 1996;72(3):231-40.
1996: Toda N; Toda M; Ayajiki K; Okamura T
Monkey central retinal artery is innervated by nitroxidergic vasodilator nerves.
Investigative ophthalmology & visual science 1996;37(11):2177-84.
1996: Zhang J X; Okamura T; Toda N
Pre- and postjunctional modulation by endothelin-1 of the adrenergic neurogenic response in canine mesenteric arteries.
European journal of pharmacology 1996;311(2-3):169-76.
1996: Okamura T; Ayajiki K; Toda N
Neural mechanism of pressor action of nitric oxide synthase inhibitor in anesthetized monkeys.
Hypertension 1996;28(3):341-6.
1996: Toda N; Ayajiki K; Okamura T
Hypercapnia relaxes cerebral arteries and potentiates neurally-induced relaxation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(5):1068-74.
1996: Toda N; Okamura T
Nitroxidergic nerve: regulation of vascular tone and blood flow in the brain.
Journal of hypertension 1996;14(4):423-34.
1996: Hayashida H; Okamura T; Tomoyoshi T; Toda N
Neurogenic nitric oxide mediates relaxation of canine corpus cavernosum.
The Journal of urology 1996;155(3):1122-7.
1995: Tanobe Y; Okamura T; Fujimura M; Toda N
Functional role and histological demonstration of nitric-oxide-mediated inhibitory nerves in dog sphincter of Oddi.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 1995;7(4):219-27.
1995: Toda N; Kimura T; Okamura T
Nitroxidergic nerve stimulation relaxes human uterine vein.
Journal of the autonomic nervous system 1995;55(3):189-92.
1995: Toda N; Uchiyama M; Okamura T
Prejunctional modulation of nitroxidergic nerve function in canine cerebral arteries.
Brain research 1995;700(1-2):213-8.
1995: Okamura T; Ayajiki K; Toda N
Basilar arterial construction caused by intracisternal NG-nitro-L-arginine in anesthetized monkeys.
Cardiovascular research 1995;30(5):663-7.
1995: Okamura T; Kimura T; Toda N
Neurogenic vasodilation in canine uterine and iliac arteries.
Journal of hypertension 1995;13(10):1163-8.
1995: Toda N; Zhang J X; Ayajiki K; Okamura T
Mechanisms underlying endothelium-independent relaxation by acetylcholine in canine retinal and cerebral arteries.
The Journal of pharmacology and experimental therapeutics 1995;274(3):1507-12.
1995: Okamura T; Uchiyama M; An J; Toda N
Nitric oxide-mediated neurogenic relaxation in monkey mesenteric veins.
Japanese journal of pharmacology 1995;68(4):405-11.
1995: Sai Y; Okamura T; Amakata Y; Toda N
Comparison of responses of canine pulmonary artery and vein to angiotensin II, bradykinin and vasopressin.
European journal of pharmacology 1995;282(1-3):235-41.
1995: Kimura T; Okamura T; Yoshida Y; Toda N
Relaxant responses to prostaglandin F2 alpha and E2 of isolated human uterine arteries.
Journal of cardiovascular pharmacology 1995;26(2):333-8.
1995: Nishikawa M; Okamura T; Toda N
[Effect of the novel calcium antagonist AE0047 on responses of isolated dog blood vessels to vasoconstricting agents and to nerve stimulation]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 1995;106(1):19-29.
1995: Okamura T; Toda N
Comparison of the effect of dopamine in primate arteries and veins.
Hypertension research : official journal of the Japanese Society of Hypertension 1995;18 Suppl 1():S35-7.
1995: Okamura T; Ide S; Toda N
Characteristics of DQ2511-induced relaxation in isolated dog, monkey and human arteries.
Pharmacology 1995;50(6):370-9.
1995: Okamura T; Yoshida K; Toda N
Nitroxidergic innervation in dog and monkey renal arteries.
Hypertension 1995;25(5):1090-5.
1995: Toda N; Yoshida K; Okamura T
Involvement of nitroxidergic and noradrenergic nerves in the relaxation of dog and monkey temporal veins.
Journal of cardiovascular pharmacology 1995;25(5):741-7.
1995: Toda N; Kitamura Y; Okamura T
Functional role of nerve-derived nitric oxide in isolated dog ophthalmic arteries.
Investigative ophthalmology & visual science 1995;36(3):563-70.
1995: Kitamura Y; Okamura T; Kani K; Toda N
Histamine actions in dog retinal central arteries as compared to those in middle cerebral and temporal arteries.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1995;11(2):167-76.
1994: Shiraishi S; Okamura T; Mori A; Toda N
Differences in adrenergic nerve and receptor function in dog internal thoracic, coronary and mesenteric arteries.
Japanese journal of pharmacology 1994;66(4):481-8.
1994: Okamura T; Toda N
Nitric oxide (NO)-mediated, vasodilator nerve function and its susceptibility to calcium antagonists.
Journal of the autonomic nervous system 1994;49 Suppl():S55-8.
1994: Okamura T; Toda N
Mechanism underlying nicotine-induced relaxation in dog saphenous arteries.
European journal of pharmacology 1994;263(1-2):85-91.
1994: Ayajiki K; Okamura T; Toda N
Neurogenic relaxations caused by nicotine in isolated cat middle cerebral arteries.
The Journal of pharmacology and experimental therapeutics 1994;270(2):795-801.
1994: Yoshida K; Okamura T; Toda N
Histological and functional studies on the nitroxidergic nerve innervating monkey cerebral, mesenteric and temporal arteries.
Japanese journal of pharmacology 1994;65(4):351-9.
1994: Okamura T; Yamazaki M; Toda N
Responses to histamine and acetylcholine in isolated monkey mesenteric veins versus arteries.
Cardiovascular research 1994;28(5):667-72.
1994: Toda N; Kitamura Y; Okamura T
Role of nitroxidergic nerve in dog retinal arterioles in vivo and arteries in vitro.
The American journal of physiology 1994;266(5 Pt 2):H1985-92.
1994: Okamura T; Toda N
Inhibition by calmodulin antagonists of the neurogenic relaxation in cerebral arteries.
European journal of pharmacology 1994;256(1):79-83.
1994: Toda N; Kimura T; Yoshida K; Bredt D S; Snyder S H; Yoshida Y; Okamura T
Human uterine arterial relaxation induced by nitroxidergic nerve stimulation.
The American journal of physiology 1994;266(4 Pt 2):H1446-50.
1994: Enokibori M; Okamura T; Toda N
Mechanism underlying substance P-induced relaxation in dog isolated superficial temporal arteries.
British journal of pharmacology 1994;111(1):77-82.
1993: Yoshida K; Okamura T; Kimura H; Bredt D S; Snyder S H; Toda N
Nitric oxide synthase-immunoreactive nerve fibers in dog cerebral and peripheral arteries.
Brain research 1993;629(1):67-72.
1993: Toda N; Okamura T
Responses to perivascular nerve stimulation of distal temporal arteries from dogs and monkeys.
Journal of cardiovascular pharmacology 1993;22(5):744-9.
1993: Toda N; Ayajiki K; Okamura T
Endothelial modulation of contractions caused by oxyhemoglobin and NG-nitro-L-arginine in isolated dog and monkey cerebral arteries.
Stroke; a journal of cerebral circulation 1993;24(10):1584-8; discussion 1589.
1993: Okamura T; Enokibori M; Toda N
Neurogenic and non-neurogenic relaxations caused by nicotine in isolated dog superficial temporal artery.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1416-21.
1993: Toda N; Enokibori M; Matsumoto T; Okamura T
Responsiveness to dopamine of isolated epicardial coronary arteries from humans, monkeys, and dogs.
Anesthesia and analgesia 1993;77(3):526-32.
1993: Wang Y; Okamura T; Toda N
Mechanisms of acetylcholine-induced relaxation in dog external and internal ophthalmic arteries.
Experimental eye research 1993;57(3):275-81.
1993: Toda N; Ayajiki K; Enokibori M; Okamura T
Monkey cerebral arterial relaxation caused by hypercapnic acidosis and hypertonic bicarbonate.
The American journal of physiology 1993;265(3 Pt 2):H929-33.
1993: Kitamura Y; Okamura T; Kani K; Toda N
Nitric oxide-mediated retinal arteriolar and arterial dilatation induced by substance P.
Investigative ophthalmology & visual science 1993;34(10):2859-65.
1993: Toda N; Ayajiki K; Okamura T
Neural mechanism underlying basilar arterial constriction by intracisternal L-NNA in anesthetized dogs.
The American journal of physiology 1993;265(1 Pt 2):H103-7.
1993: Matsumoto T; Okamura T; Kinoshita M; Toda N
Interactions of nitrovasodilators and atrial natriuretic peptide in isolated dog coronary arteries.
European journal of pharmacology 1993;237(1):31-7.
1993: Ayajiki K; Okamura T; Toda N
Nitric oxide mediates, and acetylcholine modulates, neurally induced relaxation of bovine cerebral arteries.
Neuroscience 1993;54(3):819-25.
1993: Toda N; Ayajiki K; Okamura T
Cerebroarterial relaxations mediated by nitric oxide derived from endothelium and vasodilator nerve.
Journal of vascular research 1993;30(2):61-7.
1993: Yoshida K; Okamura T; Toda N
Potentiation by hypoxia of contractions caused by angiotensin II in dog and monkey cerebral arteries.
Stroke; a journal of cerebral circulation 1993;24(3):421-5; discussion 426.
1993: Wang Y; Okamura T; Toda N
Mechanisms of histamine-induced relaxation in external and internal ophthalmic arteries.
Investigative ophthalmology & visual science 1993;34(1):41-8.
1993: Toda N; Ayajiki K; Yoshida K; Kimura H; Okamura T
Impairment by damage of the pterygopalatine ganglion of nitroxidergic vasodilator nerve function in canine cerebral and retinal arteries.
Circulation research 1993;72(1):206-13.
1993: Toda N; Kitamura Y; Okamura T
Neural mechanism of hypertension by nitric oxide synthase inhibitor in dogs.
Hypertension 1993;21(1):3-8.
1992: Okamura T; Matsumoto T; Ikemoto F; Toda N
Mechanisms of the biphasic responses to endothelin-3 in dog coronary arteries.
British journal of pharmacology 1992;107(4):1037-41.
1992: Ayajiki K; Okamura T; Toda N
Involvement of nitric oxide in endothelium-dependent, phasic relaxation caused by histamine in monkey cerebral arteries.
Japanese journal of pharmacology 1992;60(4):357-62.
1992: Okamura T; Wang Y; Toda N
Local generation and action of angiotensin II in dog iris sphincter muscle.
Experimental eye research 1992;55(4):563-8.
1992: Okamura T; Nishikawa M; Yoshida K; Toda N
AE0047, a new dihydropyridine Ca2+ entry blocker, inhibits the responses to adrenergic nerve stimulation and substance P in dog mesenteric arteries.
European journal of pharmacology 1992;220(1):27-33.
1992: Toda N; Okamura T
[Neurotransmission and nitric oxide (NO)]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 1992;100(3):173-82.
1992: Toda N; Okamura T
Different susceptibility of vasodilator nerve, endothelium and smooth muscle functions to Ca++ antagonists in cerebral arteries.
The Journal of pharmacology and experimental therapeutics 1992;261(1):234-9.
1992: Toda N; Ayajiki K; Toda H; Hatano Y; Okamura T
Mechanism underlying mannitol-induced relaxation in isolated monkey cerebral arteries.
The American journal of physiology 1992;262(3 Pt 2):H897-902.
1992: Toda N; Okamura T
Mechanism of neurally induced monkey mesenteric artery relaxation and contraction.
Hypertension 1992;19(2):161-6.
1992: Toda N; Baba H; Tanobe Y; Okamura T
Mechanism of relaxation induced by K+ and nicotine in dog duodenal longitudinal muscle.
The Journal of pharmacology and experimental therapeutics 1992;260(2):697-701.
1992: Okamura T; Aimi Y; Kimura H; Murakami K; Toda N
Existence of renin in the endothelium of human artery.
Journal of hypertension 1992;10(1):49-53.
1991: Toda N; Okamura T
Reciprocal regulation by putatively nitroxidergic and adrenergic nerves of monkey and dog temporal arterial tone.
The American journal of physiology 1991;261(6 Pt 2):H1740-5.
1991: Toda N; Okamura T
Role of nitric oxide in neurally induced cerebroarterial relaxation.
The Journal of pharmacology and experimental therapeutics 1991;258(3):1027-32.
1991: Okamura T; Yamazaki M; Toda N
Responses to dopamine of isolated human and monkey veins compared with those of the arteries.
The Journal of pharmacology and experimental therapeutics 1991;258(1):275-9.
1991: Inoue M; Okamura T; Toda N
Influence of methylene blue and oxyhemoglobin on mammalian vascular responses to sodium nitroprusside and nitroglycerin.
Archives internationales de pharmacodynamie et de thérapie 1991;311():104-21.
1991: Toda N; Kawakami M; Yamazaki M; Okamura T
Comparison of endothelium-dependent responses of monkey cerebral and temporal arteries.
British journal of pharmacology 1991;102(4):805-10.
1991: Toda N; Yoshida K; Okamura T
Analysis of the potentiating action of N(G)-nitro-L-arginine on the contraction of the dog temporal artery elicited by transmural stimulation of noradrenergic nerves.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(2):221-4.
1990: Toda N; Okamura T
Mechanism underlying the response to vasodilator nerve stimulation in isolated dog and monkey cerebral arteries.
The American journal of physiology 1990;259(5 Pt 2):H1511-7.
1990: Toda N; Okamura T
Possible role of nitric oxide in transmitting information from vasodilator nerve to cerebroarterial muscle.
Biochemical and biophysical research communications 1990;170(1):308-13.
1990: Okamura T; Yoshida K; Toda N
Suppression by methylene blue of prostaglandin I2 synthesis in isolated dog renal arteries.
The Journal of pharmacology and experimental therapeutics 1990;254(1):198-203.
1990: Toda N; Baba H; Okamura T
Role of nitric oxide in non-adrenergic, non-cholinergic nerve-mediated relaxation in dog duodenal longitudinal muscle strips.
Japanese journal of pharmacology 1990;53(2):281-4.
1990: Toda N; Okamura T
[Endothelium-derived relaxing factor (EDRF)]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 1990;95(6):295-308.
1990: Toda N; Okamura T
Comparison of the response to 5-carboxamidotryptamine and serotonin in isolated human, monkey and dog coronary arteries.
The Journal of pharmacology and experimental therapeutics 1990;253(2):676-82.
1990: Toda N; Okamura T
Beta adrenoceptor subtype in isolated human, monkey and dog epicardial coronary arteries.
The Journal of pharmacology and experimental therapeutics 1990;253(2):518-24.
1990: Okamura T; Okunishi H; Ayajiki K; Toda N
Conversion of angiotensin I to angiotensin II in dog isolated renal artery: role of two different angiotensin II-generating enzymes.
Journal of cardiovascular pharmacology 1990;15(3):353-9.
1990: Toda N; Inoue S; Okunishi H; Okamura T
Intra- and extraluminally-applied acetylcholine on the vascular tone or the response to transmural stimulation in dog isolated mesenteric arteries.
Naunyn-Schmiedeberg's archives of pharmacology 1990;341(1-2):30-6.
1990: Toda N; Okamura T
Modification by L-NG-monomethyl arginine (L-NMMA) of the response to nerve stimulation in isolated dog mesenteric and cerebral arteries.
Japanese journal of pharmacology 1990;52(1):170-3.
1990: Toda N; Ayaziki K; Okamura T
Modifications by endogenous prostaglandins of angiotensin II-induced contractions in dog and monkey cerebral and mesenteric arteries.
The Journal of pharmacology and experimental therapeutics 1990;252(1):374-9.
1990: Toda N; Minami Y; Okamura T
Inhibitory effects of L-NG-nitro-arginine on the synthesis of EDRF and the cerebroarterial response to vasodilator nerve stimulation.
Life sciences 1990;47(4):345-51.
1989: Toda N; Okamura T
Endothelium-dependent and -independent responses to vasoactive substances of isolated human coronary arteries.
The American journal of physiology 1989;257(3 Pt 2):H988-95.
1989: Okamura T; Inoue S; Toda N
Action of atrial natriuretic peptide (ANP) on dog cerebral arteries: evidence that neurogenic relaxation is not mediated by release of ANP.
British journal of pharmacology 1989;97(4):1258-64.
1989: Inoue S; Bian K; Okamura T; Okunishi H; Toda N
Mechanisms of action of eperisone on isolated dog saphenous arteries and veins.
Japanese journal of pharmacology 1989;50(3):271-82.
1989: Okamura T; Inoue S; Minami Y; Okunishi H; Toda N
Role of endothelium in the response to prostaglandin H2 in isolated dog arteries.
Japanese journal of pharmacology 1989;49(4):511-21.
1989: Toda N; Okunishi H; Okamura T
Responses to dopamine of isolated human gastroepiploic arteries.
Archives internationales de pharmacodynamie et de thérapie 1989;297():86-97.
1989: Okamura T; Minami Y; Toda N
Endothelium-dependent and -independent mechanisms of action of acetylcholine in monkey and dog isolated arteries.
Pharmacology 1989;38(5):279-88.
1989: Okamura T; Toda N
Different involvement of endothelium-derived relaxing factor and prostacyclin in vasodilator response to bradykinin in isolated dog blood vessels.
Advances in experimental medicine and biology 1989;247A():429-34.
1988: Lu W; Okamura T; Bian K; Inatomi A; Toda N
Prostaglandins involved in contractions by angiotensin II and bradykinin of isolated dog sphincter pupillae.
British journal of pharmacology 1988;95(2):544-50.
1988: Toda N; Inoue S; Okamura T; Okunishi H
Mechanism underlying relaxations caused by prostaglandins and thromboxane A2 analog in isolated dog arteries.
Journal of cardiovascular pharmacology 1988;11(3):354-62.
1988: Okamura T; Nakajima M; Toda N
Neuroeffector actions of thromboxane B2 in dog isolated mesenteric arteries.
British journal of pharmacology 1988;93(2):367-74.
1988: Toda N; Inoue S; Bian K; Okamura T
Endothelium-dependent and independent responses to prostaglandin H2 and arachidonic acid in isolated dog cerebral arteries.
The Journal of pharmacology and experimental therapeutics 1988;244(1):297-302.
1987: Okunishi H; Miyazaki M; Okamura T; Toda N
Different distribution of two types of angiotensin II-generating enzymes in the aortic wall.
Biochemical and biophysical research communications 1987;149(3):1186-92.

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