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Sharon O'Kane

Research Profile

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TOP 3
Karen So; Lisa Taylor; James A Bush; Piyush Durani; Tracey Mason; Duncan A McGrouther; Anthony Metcalfe; Sharon O'Kane; Gaynor Skotny; Mark W J Ferguson
Avotermin for scar improvement following scar revision surgery: a randomized, double-blind, within-patient, placebo-controlled, phase II clinical trial.
Nick Occleston; Anthony Metcalfe; Adam Boanas; Nicholas J Burgoyne; Kerry Nield; Sharon O'Kane; Mark W J Ferguson
Therapeutic improvement of scarring: mechanisms of scarless and scar-forming healing and approaches to the discovery of new treatments.
Mark W J Ferguson; Jonathan Duncan; Jeremy Bond; James Bush; Piyush Durani; Karen So; Lisa Taylor; Jonquille Chantrey; Tracey Mason; Gaynor James; Hugh Laverty; Nick Occleston; Abdul Sattar; Anna Ludlow; Sharon O'Kane
Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies.

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All Publications

2011: Karen So; Lisa Taylor; James A Bush; Piyush Durani; Tracey Mason; Duncan A McGrouther; Anthony Metcalfe; Sharon O'Kane; Gaynor Skotny; Mark W J Ferguson
Avotermin for scar improvement following scar revision surgery: a randomized, double-blind, within-patient, placebo-controlled, phase II clinical trial.
Plastic and reconstructive surgery 2011;128(1):163-72.
2010: Nick Occleston; Anthony Metcalfe; Adam Boanas; Nicholas J Burgoyne; Kerry Nield; Sharon O'Kane; Mark W J Ferguson
Therapeutic improvement of scarring: mechanisms of scarless and scar-forming healing and approaches to the discovery of new treatments.
Dermatology research and practice 2010;2010():.
2009: Mark W J Ferguson; Jonathan Duncan; Jeremy Bond; James Bush; Piyush Durani; Karen So; Lisa Taylor; Jonquille Chantrey; Tracey Mason; Gaynor James; Hugh Laverty; Nick Occleston; Abdul Sattar; Anna Ludlow; Sharon O'Kane
Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies.
Lancet 2009;373(9671):1264-74.
2008: Jeremy S Bond; Jonathan A L Duncan; Abdul Sattar; Adam Boanas; Tracey Mason; Sharon O'Kane; Mark W J Ferguson
Maturation of the human scar: an observational study.
Plastic and reconstructive surgery 2008;121(5):1650-8.
2008: Jeremy S Bond; Jonathan A L Duncan; Tracey Mason; Abdul Sattar; Adam Boanas; Sharon O'Kane; Mark W J Ferguson
Scar redness in humans: how long does it persist after incisional and excisional wounding?
Plastic and reconstructive surgery 2008;121(2):487-96.
2007: Simon Atkins; Alison R Loescher; Fiona M Boissonade; Keith G Smith; Nick Occleston; Sharon O'Kane; Mark W J Ferguson; Peter P Robinson
Interleukin-10 reduces scarring and enhances regeneration at a site of sciatic nerve repair.
Journal of the peripheral nervous system : JPNS 2007;12(4):269-76.
2007: Joanne E Bluff; Mark W J Ferguson; Sharon O'Kane; Grenham Ireland
Bone marrow-derived endothelial progenitor cells do not contribute significantly to new vessels during incisional wound healing.
Experimental hematology 2007;35(3):500-6.
2007: Yasunori Sasaki; Sharon O'Kane; Jill Dixon; Michael J Dixon; Mark W J Ferguson
Temporal and spatial expression of Pax9 and Sonic hedgehog during development of normal mouse palates and cleft palates in TGF-beta3 null embryos.
Archives of oral biology 2007;52(3):260-7.
2006: Jonathan A L Duncan; Jeremy S Bond; Tracey Mason; Anna Ludlow; Peter Cridland; Sharon O'Kane; Mark W J Ferguson
Visual analogue scale scoring and ranking: a suitable and sensitive method for assessing scar quality?
Plastic and reconstructive surgery 2006;118(4):909-18.
2006: Simon Atkins; Keith G Smith; Alison R Loescher; Fiona M Boissonade; Sharon O'Kane; Mark W J Ferguson; Peter P Robinson
Scarring impedes regeneration at sites of peripheral nerve repair.
Neuroreport 2006;17(12):1245-9.
2006: Joanne E Bluff; Siobhán O'Ceallaigh; Sharon O'Kane; Mark W J Ferguson; Grenham Ireland
The microcirculation in acute murine cutaneous incisional wounds shows a spatial and temporal variation in the functionality of vessels.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(4):434-42.
2004: Mark W J Ferguson; Sharon O'Kane
Scar-free healing: from embryonic mechanisms to adult therapeutic intervention.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1445):839-50.
2003: Alice H M Beare; Sharon O'Kane; Stephen M Krane; Mark W J Ferguson
Severely impaired wound healing in the collagenase-resistant mouse.
The Journal of investigative dermatology 2003;120(1):153-63.
2002: Robin van den Boom; Jacintha M Wilmink; Sharon O'Kane; Jason Wood; Mark W J Ferguson
Transforming growth factor-beta levels during second- intention healing are related to the different course of wound contraction in horses and ponies.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2002;10(3):188-94.
2000: Concepción Martínez-Alvarez; Consuelo Tudela; Julia Pérez-Miguelsanz; Sharon O'Kane; J Puerta; Mark W J Ferguson
Medial edge epithelial cell fate during palatal fusion.
Developmental biology 2000;220(2):343-57.
2000: Concepción Martínez-Alvarez; R Bonelli; Consuelo Tudela; Angel Gato; J Mena; Sharon O'Kane; Mark W J Ferguson
Bulging medial edge epithelial cells and palatal fusion.
The International journal of developmental biology 2000;44(3):331-5.
1999: Y Taya; Sharon O'Kane; Mark W J Ferguson
Pathogenesis of cleft palate in TGF-beta3 knockout mice.
Development (Cambridge, England) 1999;126(17):3869-79.
1997: Sharon O'Kane; Mark W J Ferguson
Transforming growth factor beta s and wound healing.
The international journal of biochemistry & cell biology 1997;29(1):63-78.
1996: C Martínez-Alvarez; Sharon O'Kane; Y Taya; Mark W J Ferguson
Palate development in the TGF-beta 3 knockout mouse. Low vacuum scanning electron microscopy reveals changes in the medial edge epithelium.
The International journal of developmental biology 1996;Suppl 1():115S-116S.