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Hideyuki Okano

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Physiology

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Spinal Cord Injuries

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TOP 3
Yaguchi Masae; Tabuse Masanao; Ohta Shigeki; Ohkusu-Tsukada Kozo; Takeuchi Tamaki; Yamane Junichi; Katoh Hiroyuki; Nakamura Masaya; Matsuzaki Yumi; Yamada Masayuki; Itoh Toshio; Nomura Tatsuji; Toyama Yoshiaki; Okano Hideyuki; Toda Masahiro
Transplantation of dendritic cells promotes functional recovery from spinal cord injury in common marmoset.
Murata Junko; Ohtsuka Toshiyuki; Tokunaga Akinori; Nishiike Suetaka; Inohara Hidenori; Okano Hideyuki; Kageyama Ryoichiro
Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1.
Mine Yutaka; Hayashi Takuro; Yamada Motoyuki; Okano Hideyuki; Kawase Takeshi
Environmental cue-dependent dopaminergic neuronal differentiation and functional effect of grafted neuroepithelial stem cells in parkinsonian brain.

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All Publications

2009: Yaguchi Masae; Tabuse Masanao; Ohta Shigeki; Ohkusu-Tsukada Kozo; Takeuchi Tamaki; Yamane Junichi; Katoh Hiroyuki; Nakamura Masaya; Matsuzaki Yumi; Yamada Masayuki; Itoh Toshio; Nomura Tatsuji; Toyama Yoshiaki; Okano Hideyuki; Toda Masahiro
Transplantation of dendritic cells promotes functional recovery from spinal cord injury in common marmoset.
Neuroscience research 2009;65(4):384-92.
2009: Murata Junko; Ohtsuka Toshiyuki; Tokunaga Akinori; Nishiike Suetaka; Inohara Hidenori; Okano Hideyuki; Kageyama Ryoichiro
Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1.
Journal of neuroscience research 2009;87(16):3521-34.
2009: Mine Yutaka; Hayashi Takuro; Yamada Motoyuki; Okano Hideyuki; Kawase Takeshi
Environmental cue-dependent dopaminergic neuronal differentiation and functional effect of grafted neuroepithelial stem cells in parkinsonian brain.
Neurosurgery 2009;65(4):741-53; discussion 753.
2009: Miura Kyoko; Okada Yohei; Aoi Takashi; Okada Aki; Takahashi Kazutoshi; Okita Keisuke; Nakagawa Masato; Koyanagi Michiyo; Tanabe Koji; Ohnuki Mari; Ogawa Daisuke; Ikeda Eiji; Okano Hideyuki; Yamanaka Shinya
Variation in the safety of induced pluripotent stem cell lines.
Nature biotechnology 2009;27(8):743-5.
2009: Nagoshi Narihito; Shibata Shinsuke; Nakamura Masaya; Matsuzaki Yumi; Toyama Yoshiaki; Okano Hideyuki
Neural crest-derived stem cells display a wide variety of characteristics.
Journal of cellular biochemistry 2009;107(6):1046-52.
2009: Tatsumi Kimiko; Tsuji Shoji; Miwa Hideki; Morisaku Toshinori; Nuriya Mutsuo; Orihara Minako; Kaneko Kazunari; Okano Hideyuki; Yasui Masato
Drosophila big brain does not act as a water channel, but mediates cell adhesion.
FEBS letters 2009;583(12):2077-82.
2009: Okano Hideyuki; Temple Sally
Cell types to order: temporal specification of CNS stem cells.
Current opinion in neurobiology 2009;19(2):112-9.
2009: Akamatsu Wado; DeVeale Brian; Okano Hideyuki; Cooney Austin J; van der Kooy Derek
Suppression of Oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(7):2113-24.
2009: Morikawa Satoru; Mabuchi Yo; Niibe Kunimichi; Suzuki Sadafumi; Nagoshi Narihito; Sunabori Takehiko; Shimmura Shigeto; Nagai Yasuo; Nakagawa Taneaki; Okano Hideyuki; Matsuzaki Yumi
Development of mesenchymal stem cells partially originate from the neural crest.
Biochemical and biophysical research communications 2009;379(4):1114-9.
2009: Ogawa Daisuke; Okada Yohei; Nakamura Masaya; Kanemura Yonehiro; Okano Hirotaka James; Matsuzaki Yumi; Shimazaki Takuya; Ito Mamoru; Ikeda Eiji; Tamiya Takashi; Nagao Seigo; Okano Hideyuki
Evaluation of human fetal neural stem/progenitor cells as a source for cell replacement therapy for neurological disorders: properties and tumorigenicity after long-term in vitro maintenance.
Journal of neuroscience research 2009;87(2):307-17.
2009: Kumagai Gentaro; Okada Yohei; Yamane Junichi; Nagoshi Narihito; Kitamura Kazuya; Mukaino Masahiko; Tsuji Osahiko; Fujiyoshi Kanehiro; Katoh Hiroyuki; Okada Seiji; Shibata Shinsuke; Matsuzaki Yumi; Toh Satoshi; Toyama Yoshiaki; Nakamura Masaya; Okano Hideyuki
Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury.
PloS one 2009;4(11):e7706.
2008: Yamada Masayuki; Momoshima Suketaka; Masutani Yoshitaka; Fujiyoshi Kanehiro; Abe Osamu; Nakamura Masaya; Aoki Shigeki; Tamaoki Norikazu; Okano Hideyuki
Diffusion-tensor neuronal fiber tractography and manganese-enhanced MR imaging of primate visual pathway in the common marmoset: preliminary results.
Radiology 2008;249(3):855-64.
2008: Naka Hayato; Nakamura Shiho; Shimazaki Takuya; Okano Hideyuki
Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development.
Nature neuroscience 2008;11(9):1014-23.
2008: Ozawa Yoko; Nakao Keiko; Kurihara Toshihide; Shimazaki Takuya; Shimmura Shigeto; Ishida Susumu; Yoshimura Akihiko; Tsubota Kazuo; Okano Hideyuki
Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation.
The Journal of biological chemistry 2008;283(36):24561-70.
2008: Miyagi Satoru; Masui Shinji; Niwa Hitoshi; Saito Tetsuichiro; Shimazaki Takuya; Okano Hideyuki; Nishimoto Masazumi; Muramatsu Masami; Iwama Atsushi; Okuda Akihiko
Consequence of the loss of Sox2 in the developing brain of the mouse.
FEBS letters 2008;582(18):2811-5.
2008: Kurihara Toshihide; Ozawa Yoko; Nagai Norihiro; Shinoda Kei; Noda Kousuke; Imamura Yutaka; Tsubota Kazuo; Okano Hideyuki; Oike Yuichi; Ishida Susumu
Angiotensin II type 1 receptor signaling contributes to synaptophysin degradation and neuronal dysfunction in the diabetic retina.
Diabetes 2008;57(8):2191-8.
2008: Okano Hideyuki; Sawamoto Kazunobu
Neural stem cells: involvement in adult neurogenesis and CNS repair.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2008;363(1500):2111-22.
2008: Okano Hideyuki; Yanagida Toshio; Iriki Atsushi
Introduction. Japan: its tradition and hot topics in biological sciences.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2008;363(1500):2067-9.
2008: Kawahara Hironori; Imai Takao; Imataka Hiroaki; Tsujimoto Masafumi; Matsumoto Ken; Okano Hideyuki
Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.
The Journal of cell biology 2008;181(4):639-53.
2008: Nagoshi Narihito; Shibata Shinsuke; Kubota Yoshiaki; Nakamura Masaya; Nagai Yasuo; Satoh Etsuko; Morikawa Satoru; Okada Yohei; Mabuchi Yo; Katoh Hiroyuki; Okada Seiji; Fukuda Keiichi; Suda Toshio; Matsuzaki Yumi; Toyama Yoshiaki; Okano Hideyuki
Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad.
Cell stem cell 2008;2(4):392-403.
2008: Sunabori Takehiko; Tokunaga Akinori; Nagai Takeharu; Sawamoto Kazunobu; Okabe Masaru; Miyawaki Atsushi; Matsuzaki Yumi; Miyata Takaki; Okano Hideyuki
Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors.
Journal of cell science 2008;121(Pt 8):1204-12.
2008: Ohta Shigeki; Ueda Yoko; Yaguchi Masae; Matsuzaki Yumi; Nakamura Masaya; Toyama Yoshiaki; Tanioka Yoshikuni; Tamaoki Norikazu; Nomura Tatsuji; Okano Hideyuki; Kawakami Yutaka; Toda Masahiro
Isolation and characterization of dendritic cells from common marmosets for preclinical cell therapy studies.
Immunology 2008;123(4):566-74.
2008: Murata Hiroaki; Tsuji Shingo; Tsujii Masahiko; Nakamura Toru; Fu Hai Ying; Eguchi Hiroshi; Asahi Kayoko; Okano Hideyuki; Kawano Sunao; Hayashi Norio
Helicobacter pylori infection induces candidate stem cell marker Musashi-1 in the human gastric epithelium.
Digestive diseases and sciences 2008;53(2):363-9.
2008: Renault-Mihara Francois; Okada Seiji; Shibata Shinsuke; Nakamura Masaya; Toyama Yoshiaki; Okano Hideyuki
Spinal cord injury: emerging beneficial role of reactive astrocytes' migration.
The international journal of biochemistry & cell biology 2008;40(9):1649-53.
2008: Ma Dexuan; Lu Li; Boneva Nadezhda B; Warashina Shogo; Kaplamadzhiev Desislav B; Mori Yoshimi; Nakaya Masa-aki; Kikuchi Mitsuru; Tonchev Anton B; Okano Hideyuki; Yamashima Tetsumori
Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus.
Hippocampus 2008;18(3):326-33.
2007: Hattori Yujiro; Ohta Shigeki; Hamada Kenji; Yamada-Okabe Hisafumi; Kanemura Yonehiro; Matsuzaki Yumi; Okano Hideyuki; Kawakami Yutaka; Toda Masahiro
Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1.
Biochemical and biophysical research communications 2007;364(4):737-42.
2007: Yoshitake Akihiro; Mori Atsuo; Shimizu Hideyuki; Ueda Toshihiko; Kabei Nobuyuki; Hachiya Takashi; Okano Hideyuki; Yozu Ryohei
Use of an epidural cooling catheter with a closed countercurrent lumen to protect against ischemic spinal cord injury in pigs.
The Journal of thoracic and cardiovascular surgery 2007;134(5):1220-6.
2007: Marumo Takeshi; Hishikawa Keiichi; Matsuzaki Yumi; Imai Naohiko; Takase Osamu; Shimosawa Tatsuo; Okano Hideyuki; Fujita Toshiro
Angiotensin II type 1 receptor blockade prevents decrease in adult stem-like cells in kidney after ureteral obstruction.
European journal of pharmacology 2007;573(1-3):216-20.
2007: Fujita Jun; Mori Mitsuharu; Kawada Hiroshi; Ieda Yasuyo; Tsuma Mitsuyo; Matsuzaki Yumi; Kawaguchi Haruko; Yagi Takashi; Yuasa Shinsuke; Endo Jin; Hotta Tomomitsu; Ogawa Satoshi; Okano Hideyuki; Yozu Ryohei; Ando Kiyoshi; Fukuda Keiichi
Administration of granulocyte colony-stimulating factor after myocardial infarction enhances the recruitment of hematopoietic stem cell-derived myofibroblasts and contributes to cardiac repair.
Stem cells (Dayton, Ohio) 2007;25(11):2750-9.
2007: Adachi Kazuhide; Mirzadeh Zaman; Sakaguchi Masanori; Yamashita Toru; Nikolcheva Tania; Gotoh Yukiko; Peltz Gary; Gong Leyi; Kawase Takeshi; Alvarez-Buylla Arturo; Okano Hideyuki; Sawamoto Kazunobu
Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone.
Stem cells (Dayton, Ohio) 2007;25(11):2827-36.
2007: Fujiyoshi Kanehiro; Yamada Masayuki; Nakamura Masaya; Yamane Junichi; Katoh Hiroyuki; Kitamura Kazuya; Kawai Kenji; Okada Seiji; Momoshima Suketaka; Toyama Yoshiaki; Okano Hideyuki
In vivo tracing of neural tracts in the intact and injured spinal cord of marmosets by diffusion tensor tractography.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(44):11991-8.
2007: Ishibashi Satoru; Kuroiwa Toshihiko; Sakaguchi Masanori; Sun Liyuan; Kadoya Toshihiko; Okano Hideyuki; Mizusawa Hidehiro
Galectin-1 regulates neurogenesis in the subventricular zone and promotes functional recovery after stroke.
Experimental neurology 2007;207(2):302-13.
2007: Imai Naohiko; Hishikawa Keiichi; Marumo Takeshi; Hirahashi Junichi; Inowa Toshihiko; Matsuzaki Yumi; Okano Hideyuki; Kitamura Tadaichi; Salant David; Fujita Toshiro
Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury.
Stem cells (Dayton, Ohio) 2007;25(10):2469-75.
2007: Okano Hideyuki
Isolation and identification of putative stem/progenitor cells from human cycling endometrium.
The journal of obstetrics and gynaecology research 2007;33 Suppl 1():S56-7.
2007: Okano Hideyuki; Sakaguchi Masanori; Ohki Koichi; Suzuki Norihiro; Sawamoto Kazunobu
Regeneration of the central nervous system using endogenous repair mechanisms.
Journal of neurochemistry 2007;102(5):1459-65.
2007: Kitamura Kazuya; Iwanami Akio; Nakamura Masaya; Yamane Junichi; Watanabe Kota; Suzuki Yoshinori; Miyazawa Daisuke; Shibata Shinsuke; Funakoshi Hiroshi; Miyatake Shinichi; Coffin Robert S; Nakamura Toshikazu; Toyama Yoshiaki; Okano Hideyuki
Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury.
Journal of neuroscience research 2007;85(11):2332-42.
2007: Okano Hideyuki; Kaneko Shinjiro; Okada Seiji; Iwanami Akio; Nakamura Masaya; Toyama Yoshiaki
Regeneration-based therapies for spinal cord injuries.
Neurochemistry international 2007;51(2-4):68-73.
2007: Izumi-Nagai Kanako; Nagai Norihiro; Ozawa Yoko; Mihara Masahiko; Ohsugi Yoshiyuki; Kurihara Toshihide; Koto Takashi; Satofuka Shingo; Inoue Makoto; Tsubota Kazuo; Okano Hideyuki; Oike Yuichi; Ishida Susumu
Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularization.
The American journal of pathology 2007;170(6):2149-58.
2007: Iijima Takatoshi; Ogura Hiroo; Takatsuki Kanako; Kawahara Shigenori; Wakabayashi Kenichiro; Nakayama Daisuke; Fujioka Masato; Kimura Yuki; Bernstein Alan; Okano Hirotaka James; Kirino Yutaka; Okano Hideyuki
Impaired motor functions in mice lacking the RNA-binding protein Hzf.
Neuroscience research 2007;58(2):183-9.
2007: Hayakawa-Yano Yoshika; Nishida Keigo; Fukami Shinichi; Gotoh Yukiko; Hirano Toshio; Nakagawa Toshiyuki; Shimazaki Takuya; Okano Hideyuki
Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord.
Stem cells (Dayton, Ohio) 2007;25(6):1410-22.
2007: Watanabe Kenta; Kondo Kenji; Takeuchi Naonobu; Okano Hideyuki; Yamasoba Tatsuya
Musashi-1 expression in postnatal mouse olfactory epithelium.
Neuroreport 2007;18(7):641-4.
2007: Sakaguchi M; Imaizumi Y; Okano H
Expression and function of galectin-1 in adult neural stem cells.
Cellular and molecular life sciences : CMLS 2007;64(10):1254-8.
2007: Koide Yoko; Morikawa Satoru; Mabuchi Yo; Muguruma Yukari; Hiratsu Emi; Hasegawa Kohji; Kobayashi Makoto; Ando Kiyoshi; Kinjo Kentaro; Okano Hideyuki; Matsuzaki Yumi
Two distinct stem cell lineages in murine bone marrow.
Stem cells (Dayton, Ohio) 2007;25(5):1213-21.
2007: Kato Naoko; Shimmura Shigeto; Kawakita Tetsuya; Miyashita Hideyuki; Ogawa Yoko; Yoshida Satoru; Higa Kazunari; Okano Hideyuki; Tsubota Kazuo
Beta-catenin activation and epithelial-mesenchymal transition in the pathogenesis of pterygium.
Investigative ophthalmology & visual science 2007;48(4):1511-7.
2007: Ozawa Yoko; Nakao Keiko; Shimazaki Takuya; Shimmura Shigeto; Kurihara Toshihide; Ishida Susumu; Yoshimura Akihiko; Tsubota Kazuo; Okano Hideyuki
SOCS3 is required to temporally fine-tune photoreceptor cell differentiation.
Developmental biology 2007;303(2):591-600.
2007: Masuda Hirotaka; Maruyama Tetsuo; Hiratsu Emi; Yamane Junichi; Iwanami Akio; Nagashima Takashi; Ono Masanori; Miyoshi Hiroyuki; Okano Hirotaka James; Ito Mamoru; Tamaoki Norikazu; Nomura Tatsuji; Okano Hideyuki; Matsuzaki Yumi; Yoshimura Yasunori
Noninvasive and real-time assessment of reconstructed functional human endometrium in NOD/SCID/gamma c(null) immunodeficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(6):1925-30.
2007: Kanai Ryuichi; Tomita Hideyuki; Hirose Yuichi; Ohba Shigeo; Goldman Steven; Okano Hideyuki; Kawase Takeshi; Yazaki Takahito
Augmented therapeutic efficacy of an oncolytic herpes simplex virus type 1 mutant expressing ICP34.5 under the transcriptional control of musashi1 promoter in the treatment of malignant glioma.
Human gene therapy 2007;18(1):63-73.
2007: Watanabe Kota; Nakamura Masaya; Okano Hideyuki; Toyama Yoshiaki
Establishment of three-dimensional culture of neural stem/progenitor cells in collagen Type-1 Gel.
Restorative neurology and neuroscience 2007;25(2):109-17.
2006: Kurihara Toshihide; Ozawa Yoko; Shinoda Kei; Nagai Norihiro; Inoue Makoto; Oike Yuichi; Tsubota Kazuo; Ishida Susumu; Okano Hideyuki
Neuroprotective effects of angiotensin II type 1 receptor (AT1R) blocker, telmisartan, via modulating AT1R and AT2R signaling in retinal inflammation.
Investigative ophthalmology & visual science 2006;47(12):5545-52.
2006: Kaneko Shinjiro; Iwanami Akio; Nakamura Masaya; Kishino Akiyoshi; Kikuchi Kaoru; Shibata Shinsuke; Okano Hirotaka J; Ikegami Takeshi; Moriya Ayako; Konishi Osamu; Nakayama Chikao; Kumagai Kazuo; Kimura Toru; Sato Yasufumi; Goshima Yoshio; Taniguchi Masahiko; Ito Mamoru; He Zhigang; Toyama Yoshiaki; Okano Hideyuki
A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord.
Nature medicine 2006;12(12):1380-9.
2006: Kanai Ryuichi; Eguchi Keisuke; Takahashi Miwa; Goldman Steven; Okano Hideyuki; Kawase Takeshi; Yazaki Takahito
Enhanced therapeutic efficacy of oncolytic herpes vector G207 against human non-small cell lung cancer--expression of an RNA-binding protein, Musashi1, as a marker for the tailored gene therapy.
The journal of gene medicine 2006;8(11):1329-40.
2006: Sasaki Tsutomu; Kitagawa Kazuo; Yagita Yoshiki; Sugiura Shiro; Omura-Matsuoka Emi; Tanaka Shigeru; Matsushita Kohji; Okano Hideyuki; Tsujimoto Yoshihide; Hori Masatsugu
Bcl2 enhances survival of newborn neurons in the normal and ischemic hippocampus.
Journal of neuroscience research 2006;84(6):1187-96.
2006: Kaneko Naoko; Okano Hideyuki; Sawamoto Kazunobu
Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(10):1145-59.
2006: Arata Yukinobu; Kouike Hiroko; Zhang Yanping; Herman Michael A; Okano Hideyuki; Sawa Hitoshi
Wnt signaling and a Hox protein cooperatively regulate psa-3/Meis to determine daughter cell fate after asymmetric cell division in C. elegans.
Developmental cell 2006;11(1):105-15.
2006: Okada Seiji; Nakamura Masaya; Katoh Hiroyuki; Miyao Tamaki; Shimazaki Takuya; Ishii Ken; Yamane Junichi; Yoshimura Akihiko; Iwamoto Yukihide; Toyama Yoshiaki; Okano Hideyuki
Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.
Nature medicine 2006;12(7):829-34.
2006: Murata Junko; Tokunaga Akinori; Okano Hideyuki; Kubo Takeshi
Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification.
The Journal of comparative neurology 2006;497(3):502-18.
2006: Ninomiya Mikiko; Yamashita Toru; Araki Nobuo; Okano Hideyuki; Sawamoto Kazunobu
Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying cells in the subventricular zone.
Neuroscience letters 2006;403(1-2):63-7.
2006: Yamashita Toru; Ninomiya Mikiko; Hernández Acosta Pilar; García-Verdugo Jose Manuel; Sunabori Takehiko; Sakaguchi Masanori; Adachi Kazuhide; Kojima Takuro; Hirota Yuki; Kawase Takeshi; Araki Nobuo; Abe Koji; Okano Hideyuki; Sawamoto Kazunobu
Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(24):6627-36.
2006: Sakaguchi Masanori; Shingo Tetsuro; Shimazaki Takuya; Okano Hirotaka James; Shiwa Mieko; Ishibashi Satoru; Oguro Hideyuki; Ninomiya Mikiko; Kadoya Toshihiko; Horie Hidenori; Shibuya Akira; Mizusawa Hidehiro; Poirier Françoise; Nakauchi Hiromitsu; Sawamoto Kazunobu; Okano Hideyuki
A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(18):7112-7.
2006: Miyagi Satoru; Nishimoto Masazumi; Saito Tetsuichiro; Ninomiya Mikiko; Sawamoto Kazunobu; Okano Hideyuki; Muramatsu Masami; Oguro Hideyuki; Iwama Atsushi; Okuda Akihiko
The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon.
The Journal of biological chemistry 2006;281(19):13374-81.
2006: Fujioka Masato; Kanzaki Sho; Okano Hirotaka James; Masuda Masatsugu; Ogawa Kaoru; Okano Hideyuki
Proinflammatory cytokines expression in noise-induced damaged cochlea.
Journal of neuroscience research 2006;83(4):575-83.
2006: Kawada Hiroshi; Takizawa Shunya; Takanashi Tomomi; Morita Yuko; Fujita Jun; Fukuda Keiichi; Takagi Shigeharu; Okano Hideyuki; Ando Kiyoshi; Hotta Tomomitsu
Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem/progenitor cells and transition of bone marrow-derived neuronal cells.
Circulation 2006;113(5):701-10.
2006: Sawamoto Kazunobu; Wichterle Hynek; Gonzalez-Perez Oscar; Cholfin Jeremy A; Yamada Masayuki; Spassky Nathalie; Murcia Noel S; Garcia-Verdugo Jose Manuel; Marin Oscar; Rubenstein John L R; Tessier-Lavigne Marc; Okano Hideyuki; Alvarez-Buylla Arturo
New neurons follow the flow of cerebrospinal fluid in the adult brain.
Science (New York, N.Y.) 2006;311(5761):629-32.
2006: Nagata Hiroshi; Akiba Yasutada; Suzuki Hidekazu; Okano Hideyuki; Hibi Toshifumi
Expression of Musashi-1 in the rat stomach and changes during mucosal injury and restitution.
FEBS letters 2006;580(1):27-33.
2006: Matsumoto Arifumi; Okada Yohei; Nakamichi Masanori; Nakamura Masaya; Toyama Yoshiaki; Sobue Gen; Nagai Makiko; Aoki Masashi; Itoyama Yasuto; Okano Hideyuki
Disease progression of human SOD1 (G93A) transgenic ALS model rats.
Journal of neuroscience research 2006;83(1):119-33.
2006: Kanai R; Tomita H; Shinoda A; Takahashi M; Goldman S; Okano H; Kawase T; Yazaki T
Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashi1 promoter retargeting of gamma34.5-mediated virulence.
Gene therapy 2006;13(2):106-16.
2006: Okano H
Adult neural stem cells and central nervous system repair.
Ernst Schering Research Foundation workshop 2006;(60):215-28.
2006: Toriya Masako; Tokunaga Akinori; Sawamoto Kazunobu; Nakao Keiko; Okano Hideyuki
Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain.
Developmental neuroscience 2006;28(1-2):142-55.
2005: Ikegami Takeshi; Nakamura Masaya; Yamane Junichi; Katoh Hiroyuki; Okada Seiji; Iwanami Akio; Watanabe Kota; Ishii Ken; Kato Fumikazu; Fujita Hiroshi; Takahashi Toyomi; Okano Hirotaka James; Toyama Yoshiaki; Okano Hideyuki
Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury.
The European journal of neuroscience 2005;22(12):3036-46.
2005: Inaji Motoki; Okauchi Takashi; Ando Kiyoshi; Maeda Jun; Nagai Yuji; Yoshizaki Takahito; Okano Hideyuki; Nariai Tadashi; Ohno Kikuo; Obayashi Shigeru; Higuchi Makoto; Suhara Tetsuya
Correlation between quantitative imaging and behavior in unilaterally 6-OHDA-lesioned rats.
Brain research 2005;1064(1-2):136-45.
2005: Nakamura Masaya; Toyama Yoshiaki; Okano Hideyuki
[Transplantation of neural stem cells for spinal cord injury]
Rinsho shinkeigaku = Clinical neurology 2005;45(11):874-6.
2005: Iijima Takatoshi; Imai Takao; Kimura Yuki; Bernstein Alan; Okano Hirotaka James; Yuzaki Michisuke; Okano Hideyuki
Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):17190-5.
2005: Kanuka Hirotaka; Hiratou Tetsuo; Igaki Tatsushi; Kanda Hiroshi; Kuranaga Erina; Sawamoto Kazunobu; Aigaki Toshiro; Okano Hideyuki; Miura Masayuki
Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity.
Biochimica et biophysica acta 2005;1726(3):225-37.
2005: Mori Atsuo; Ueda Toshihiko; Hachiya Takashi; Kabei Nobuyuki; Okano Hideyuki; Yozu Ryohei; Sasaki Tatsuumi
An epidural cooling catheter protects the spinal cord against ischemic injury in pigs.
The Annals of thoracic surgery 2005;80(5):1829-33.
2005: Yamamoto S; Yoshino I; Shimazaki T; Murohashi M; Hevner R F; Lax I; Okano H; Shibuya M; Schlessinger J; Gotoh N
Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15983-8.
2005: Kanuka Hirotaka; Kuranaga Erina; Takemoto Kiwamu; Hiratou Tetsuo; Okano Hideyuki; Miura Masayuki
Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development.
The EMBO journal 2005;24(21):3793-806.
2005: Okano Hideyuki; Okada Seiji; Nakamura Masaya; Toyama Yoshiaki
Neural stem cells and regeneration of injured spinal cord.
Kidney international 2005;68(5):1927-31.
2005: Sasaki Takahiro; Iwata Satoshi; Okano Hirotaka James; Urasaki Yasuyo; Hamada Junichi; Tanaka Hirotoshi; Dang Nam H; Okano Hideyuki; Morimoto Chikao
Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats: possible involvement of Nedd9 in the differentiation of neurons after ischemia.
Stroke; a journal of cerebral circulation 2005;36(11):2457-62.
2005: Okada Seiji; Ishii Ken; Yamane Junichi; Iwanami Akio; Ikegami Takeshi; Katoh Hiroyuki; Iwamoto Yukihide; Nakamura Masaya; Miyoshi Hiroyuki; Okano Hirotaka James; Contag Christopher H; Toyama Yoshiaki; Okano Hideyuki
In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(13):1839-41.
2005: Asai Rieko; Okano Hideyuki; Yasugi Sadao
Correlation between Musashi-1 and c-hairy-1 expression and cell proliferation activity in the developing intestine and stomach of both chicken and mouse.
Development, growth & differentiation 2005;47(8):501-10.
2005: Kohyama Jun; Tokunaga Akinori; Fujita Yuko; Miyoshi Hiroyuki; Nagai Takeharu; Miyawaki Atsushi; Nakao Keiko; Matsuzaki Yumi; Okano Hideyuki
Visualization of spatiotemporal activation of Notch signaling: live monitoring and significance in neural development.
Developmental biology 2005;286(1):311-25.
2005: Suzuki Tsuyoshi; Izumoto Shuichi; Wada Kouichi; Fujimoto Yasunori; Maruno Motohiko; Yamasaki Mami; Kanemura Yonehiro; Shimazaki Takuya; Okano Hideyuki; Yoshimine Toshiki
Inhibition of glioma cell proliferation by neural stem cell factor.
Journal of neuro-oncology 2005;74(3):233-9.
2005: Tomita Yuichi; Matsumura Keisuke; Wakamatsu Yoshio; Matsuzaki Yumi; Shibuya Isao; Kawaguchi Haruko; Ieda Masaki; Kanakubo Sachiko; Shimazaki Takuya; Ogawa Satoshi; Osumi Noriko; Okano Hideyuki; Fukuda Keiichi
Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart.
The Journal of cell biology 2005;170(7):1135-46.
2005: Tamura Mutsuhiro; Nakamura Masaya; Ogawa Yuto; Toyama Yoshiaki; Miura Masayuki; Okano Hideyuki
Targeted expression of anti-apoptotic protein p35 in oligodendrocytes reduces delayed demyelination and functional impairment after spinal cord injury.
Glia 2005;51(4):312-21.
2005: Sahara Makoto; Sata Masataka; Matsuzaki Yumi; Tanaka Kimie; Morita Toshihiro; Hirata Yasunobu; Okano Hideyuki; Nagai Ryozo
Comparison of various bone marrow fractions in the ability to participate in vascular remodeling after mechanical injury.
Stem cells (Dayton, Ohio) 2005;23(7):874-8.
2005: Yamashita Toru; Sawamoto Kazunobu; Suzuki Shigeaki; Suzuki Norihiro; Adachi Kazuhide; Kawase Takeshi; Mihara Masahiko; Ohsugi Yoshiyuki; Abe Koji; Okano Hideyuki
Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons.
Journal of neurochemistry 2005;94(2):459-68.
2005: Uchida Koichi; Momiyama Toshihiko; Okano Hideyuki; Yuzaki Michisuke; Koizumi Amane; Mine Yutaka; Kawase Takeshi
Potential functional neural repair with grafted neural stem cells of early embryonic neuroepithelial origin.
Neuroscience research 2005;52(3):276-86.
2005: Nakamura Masaya; Okada Seiji; Toyama Yoshiaki; Okano Hideyuki
Role of IL-6 in spinal cord injury in a mouse model.
Clinical reviews in allergy & immunology 2005;28(3):197-204.
2005: Hishikawa Keiichi; Marumo Takeshi; Miura Shigeki; Nakanishi Asato; Matsuzaki Yumi; Shibata Katsunori; Ichiyanagi Tomoko; Kohike Hiroko; Komori Takuya; Takahashi Ichiro; Takase Osamu; Imai Naohiko; Yoshikawa Masahiro; Inowa Toshihiko; Hayashi Matsuhiko; Nakaki Toshio; Nakauchi Hiromitsu; Okano Hideyuki; Fujita Toshiro
Musculin/MyoR is expressed in kidney side population cells and can regulate their function.
The Journal of cell biology 2005;169(6):921-8.
2005: Matsuda Yoshimasa; Wakamatsu Yoshio; Kohyama Jun; Okano Hideyuki; Fukuda Kimiko; Yasugi Sadao
Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development.
Development (Cambridge, England) 2005;132(12):2783-93.
2005: Okano Hideyuki; Kawahara Hironori; Toriya Masako; Nakao Keio; Shibata Shinsuke; Imai Takao
Function of RNA-binding protein Musashi-1 in stem cells.
Experimental cell research 2005;306(2):349-56.
2005: Suzuki Shigeaki; Yamashita Toru; Tanaka Kortaro; Hattori Hidenori; Sawamoto Kazunobu; Okano Hideyuki; Suzuki Norihiro
Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(6):685-93.
2005: Yoda Akinori; Kouike Hiroko; Okano Hideyuki; Sawa Hitoshi
Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans.
Development (Cambridge, England) 2005;132(8):1885-93.
2005: Iwanami A; Yamane J; Katoh H; Nakamura M; Momoshima S; Ishii H; Tanioka Y; Tamaoki N; Nomura T; Toyama Y; Okano H
Establishment of graded spinal cord injury model in a nonhuman primate: the common marmoset.
Journal of neuroscience research 2005;80(2):172-81.
2005: Iwanami A; Kaneko S; Nakamura M; Kanemura Y; Mori H; Kobayashi S; Yamasaki M; Momoshima S; Ishii H; Ando K; Tanioka Y; Tamaoki N; Nomura T; Toyama Y; Okano H
Transplantation of human neural stem cells for spinal cord injury in primates.
Journal of neuroscience research 2005;80(2):182-90.
2005: Yano Masato; Okano Hirotaka J; Okano Hideyuki
Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation.
The Journal of biological chemistry 2005;280(13):12690-9.
2005: Akamatsu Wado; Fujihara Hiroaki; Mitsuhashi Takayuki; Yano Masato; Shibata Shinsuke; Hayakawa Yoshika; Okano Hirotaka James; Sakakibara Shin-Ichi; Takano Hiroshi; Takano Toshiya; Takahashi Takao; Noda Tetsuo; Okano Hideyuki
The RNA-binding protein HuD regulates neuronal cell identity and maturation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4625-30.
2005: Hishikawa Keiichi; Marumo Takeshi; Miura Shigeki; Nakanishi Asato; Matsuzaki Yumi; Shibata Katsunori; Kohike Hiroko; Komori Takuya; Hayashi Matsuhiko; Nakaki Toshio; Nakauchi Hiromitsu; Okano Hideyuki; Fujita Toshiro
Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16.
Biochemical and biophysical research communications 2005;328(1):288-91.
2005: Hirota Yuki; Sawamoto Kazunobu; Takahashi Kuniaki; Ueda Ryu; Okano Hideyuki
The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster.
Development genes and evolution 2005;215(2):90-6.
2005: Inaji Motoki; Yoshizaki Takahito; Okauchi Takashi; Maeda Jun; Nagai Yuji; Nariai Tadashi; Ohno Kikuo; Ando Kiyoshi; Okano Hideyuki; Obayashi Shigeru; Suhara Tetsuya
In vivo PET measurements with [11C]PE2I to evaluate fetal mesencephalic transplantations to unilateral 6-OHDA-lesioned rats.
Cell transplantation 2005;14(9):655-63.
2004: Kawada Hiroshi; Fujita Jun; Kinjo Kentaro; Matsuzaki Yumi; Tsuma Mitsuyo; Miyatake Hiroko; Muguruma Yukari; Tsuboi Kosuke; Itabashi Yuji; Ikeda Yasuo; Ogawa Satoshi; Okano Hideyuki; Hotta Tomomitsu; Ando Kiyoshi; Fukuda Keiichi
Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction.
Blood 2004;104(12):3581-7.
2004: Okada Yohei; Shimazaki Takuya; Sobue Gen; Okano Hideyuki
Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells.
Developmental biology 2004;275(1):124-42.
2004: Uchida Koichi; Mukai Makio; Okano Hideyuki; Kawase Takeshi
Possible oncogenicity of subventricular zone neural stem cells: case report.
Neurosurgery 2004;55(4):977-8.
2004: Ishibashi Satoru; Sakaguchi Masanori; Kuroiwa Toshihiko; Yamasaki Mami; Kanemura Yonehiro; Shizuko Ichinose; Shimazaki Takuya; Onodera Masafumi; Okano Hideyuki; Mizusawa Hidehiro
Human neural stem/progenitor cells, expanded in long-term neurosphere culture, promote functional recovery after focal ischemia in Mongolian gerbils.
Journal of neuroscience research 2004;78(2):215-23.
2004: Tokunaga Akinori; Kohyama Jun; Yoshida Tetsu; Nakao Keiko; Sawamoto Kazunobu; Okano Hideyuki
Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain.
Journal of neurochemistry 2004;90(1):142-54.
2004: Ozawa Yoko; Nakao Keiko; Shimazaki Takuya; Takeda Junji; Akira Shizuo; Ishihara Katsuhiko; Hirano Toshio; Oguchi Yoshihisa; Okano Hideyuki
Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina.
Molecular and cellular neurosciences 2004;26(2):258-70.
2004: Yoshizaki Takahito; Inaji Motoki; Kouike Hiroko; Shimazaki Takuya; Sawamoto Kazunobu; Ando Kiyoshi; Date Isao; Kobayashi Kazuto; Suhara Tetsuya; Uchiyama Yasuo; Okano Hideyuki
Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells.
Neuroscience letters 2004;363(1):33-7.
2004: Mikami Yuji; Okano Hideyuki; Sakaguchi Masanori; Nakamura Masaya; Shimazaki Takuya; Okano Hirotaka James; Kawakami Yutaka; Toyama Yoshiaki; Toda Masahiro
Implantation of dendritic cells in injured adult spinal cord results in activation of endogenous neural stem/progenitor cells leading to de novo neurogenesis and functional recovery.
Journal of neuroscience research 2004;76(4):453-65.
2004: Okada S; Nakamura M; Mikami Y; Shimazaki T; Mihara M; Ohsugi Y; Iwamoto Y; Yoshizaki K; Kishimoto T; Toyama Y; Okano H
Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury.
Journal of neuroscience research 2004;76(2):265-76.
2004: Ohba Hiroyuki; Chiyoda Tatsuyuki; Endo Emmy; Yano Masato; Hayakawa Yoshika; Sakaguchi Masanori; Darnell Robert B; Okano Hirotaka J; Okano Hideyuki
Sox21 is a repressor of neuronal differentiation and is antagonized by YB-1.
Neuroscience letters 2004;358(3):157-60.
2004: Watanabe Kota; Nakamura Masaya; Iwanami Akio; Fujita Yuko; Kanemura Yonehiro; Toyama Yoshiaki; Okano Hideyuki
Comparison between fetal spinal-cord- and forebrain-derived neural stem/progenitor cells as a source of transplantation for spinal cord injury.
Developmental neuroscience 2004;26(2-4):275-87.
2004: Ieda Masaki; Fukuda Keiichi; Hisaka Yasuyo; Kimura Kensuke; Kawaguchi Haruko; Fujita Jun; Shimoda Kouji; Takeshita Eiko; Okano Hideyuki; Kurihara Yukiko; Kurihara Hiroki; Ishida Junji; Fukamizu Akiyoshi; Federoff Howard J; Ogawa Satoshi
Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression.
The Journal of clinical investigation 2004;113(6):876-84.
2004: Matsuzaki Yumi; Kinjo Kentaro; Mulligan Richard C; Okano Hideyuki
Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells.
Immunity 2004;20(1):87-93.
2004: Murata Junko; Murayama Ayako; Horii Arata; Doi Katsumi; Harada Tamotsu; Okano Hideyuki; Kubo Takeshi
Expression of Musashi1, a neural RNA-binding protein, in the cochlea of young adult mice.
Neuroscience letters 2004;354(3):201-4.
2003: Okano Hideyuki; Yoshizaki Takahito; Okada Seiji
[Regeneration of central nervous system: its concept and strategy]
Rinsho shinkeigaku = Clinical neurology 2003;43(11):824-6.
2003: Kanuka Hirotaka; Kuranaga Erina; Hiratou Tetsuo; Igaki Tatsushi; Nelson Bryce; Okano Hideyuki; Miura Masayuki
Cytosol-endoplasmic reticulum interplay by Sec61alpha translocon in polyglutamine-mediated neurotoxicity in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11723-8.
2003: Hisahara Shin; Okano Hideyuki; Miura Masayuki
Caspase-mediated oligodendrocyte cell death in the pathogenesis of autoimmune demyelination.
Neuroscience research 2003;46(4):387-97.
2003: Okano Hideyuki; Ogawa Yuto; Nakamura Masaya; Kaneko Shinjiro; Iwanami Akio; Toyama Yoshiaki
Transplantation of neural stem cells into the spinal cord after injury.
Seminars in cell & developmental biology 2003;14(3):191-8.
2003: Okano Hideyuki
Making and repairing the mammalian brain: Introduction.
Seminars in cell & developmental biology 2003;14(3):159.
2003: Uchida Koichi; Okano Hideyuki; Hayashi Takuro; Mine Yutaka; Tanioka Yoshikuni; Nomura Tatsuji; Kawase Takeshi
Grafted swine neuroepithelial stem cells can form myelinated axons and both efferent and afferent synapses with xenogeneic rat neurons.
Journal of neuroscience research 2003;72(6):661-9.
2003: Yuasa Yoshihiro; Okabe Masataka; Yoshikawa Shingo; Tabuchi Katsuhiko; Xiong Wen-Cheng; Hiromi Yasushi; Okano Hideyuki
Drosophila homeodomain protein REPO controls glial differentiation by cooperating with ETS and BTB transcription factors.
Development (Cambridge, England) 2003;130(11):2419-28.
2003: Sasaki Tsutomu; Kitagawa Kazuo; Sugiura Shiro; Omura-Matsuoka Emi; Tanaka Shigeru; Yagita Yoshiki; Okano Hideyuki; Matsumoto Masayasu; Hori Masatsugu
Implication of cyclooxygenase-2 on enhanced proliferation of neural progenitor cells in the adult mouse hippocampus after ischemia.
Journal of neuroscience research 2003;72(4):461-71.
2003: Okada Seiji; Okano Hideyuki
[Regulatory mechanisms of neural stem cell and strategies for therapy]
Nippon rinsho. Japanese journal of clinical medicine 2003;61(3):449-56.
2002: Hirota Yuki; Sawamoto Kazunobu; Okano Hideyuki
tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila.
Mechanisms of development 2002;119 Suppl 1():S279-83.
2002: Hirota Yuki; Sawamoto Kazunobu; Okano Hideyuki
tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila.
Gene expression patterns : GEP 2002;2(3-4):323-7.
2002: Okano Hideyuki; Yoshizaki Takahito; Shimazaki Takuya; Sawamoto Kazunobu
Isolation and transplantation of dopaminergic neurons and neural stem cells.
Parkinsonism & related disorders 2002;9(1):23-8.
2002: Okano Hideyuki
Neural stem cells: progression of basic research and perspective for clinical application.
The Keio journal of medicine 2002;51(3):115-28.
2002: Ogawa Y; Sawamoto K; Miyata T; Miyao S; Watanabe M; Nakamura M; Bregman B S; Koike M; Uchiyama Y; Toyama Y; Okano H
Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats.
Journal of neuroscience research 2002;69(6):925-33.
2002: Murayama Ayako; Matsuzaki Yumi; Kawaguchi Ayano; Shimazaki Takuya; Okano Hideyuki
Flow cytometric analysis of neural stem cells in the developing and adult mouse brain.
Journal of neuroscience research 2002;69(6):837-47.
2002: Yagita Yoshiki; Kitagawa Kazuo; Sasaki Tsutomu; Miyata Takaki; Okano Hideyuki; Hori Masatsugu; Matsumoto Masayasu
Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia.
Journal of neuroscience research 2002;69(6):750-6.
2002: Okano Hideyuki
Stem cell biology of the central nervous system.
Journal of neuroscience research 2002;69(6):698-707.
2002: Kuranaga Erina; Kanuka Hirotaka; Igaki Tatsushi; Sawamoto Kazunobu; Ichijo Hidenori; Okano Hideyuki; Miura Masayuki
Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila.
Nature cell biology 2002;4(9):705-10.
2002: Shibata Mamoru; Yamawaki Takemori; Sasaki Takahiro; Hattori Hidenori; Hamada Junichi; Fukuuchi Yasuo; Okano Hideyuki; Miura Masayuki
Upregulation of Akt phosphorylation at the early stage of middle cerebral artery occlusion in mice.
Brain research 2002;942(1-2):1-10.
2002: Okano Hideyuki; Imai Takao; Okabe Masataka
Musashi: a translational regulator of cell fate.
Journal of cell science 2002;115(Pt 7):1355-9.
2002: Takasawa Ken-ichiro; Kitagawa Kazuo; Yagita Yoshiki; Sasaki Tsutomu; Tanaka Shigeru; Matsushita Kohji; Ohstuki Toshiho; Miyata Takaki; Okano Hideyuki; Hori Masatsugu; Matsumoto Masayasu
Increased proliferation of neural progenitor cells but reduced survival of newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(3):299-307.
2002: Okano Hideyuki
[Neural stem cells: their identification, isolation and potential therapeutic application]
Seikagaku. The Journal of Japanese Biochemical Society 2002;74(1):17-26.
2001: Okano H
[Neural stem cells: the basic biology and prospects for brain repair]
Rinsho shinkeigaku = Clinical neurology 2001;41(12):1036-40.
2001: Yamamoto N; Yamamoto S; Inagaki F; Kawaichi M; Fukamizu A; Kishi N; Matsuno K; Nakamura K; Weinmaster G; Okano H; Nakafuku M
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.
The Journal of biological chemistry 2001;276(48):45031-40.
2001: Sakakibara S; Nakamura Y; Satoh H; Okano H
Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(20):8091-107.
2001: Sawamoto K; Yamamoto A; Kawaguchi A; Yamaguchi M; Mori K; Goldman S A; Okano H
Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage-specific neural promoters.
Journal of neuroscience research 2001;65(3):220-7.
2001: Yagita Y; Kitagawa K; Ohtsuki T; Takasawa Ki; Miyata T; Okano H; Hori M; Matsumoto M
Neurogenesis by progenitor cells in the ischemic adult rat hippocampus.
Stroke; a journal of cerebral circulation 2001;32(8):1890-6.
2001: Imai T; Tokunaga A; Yoshida T; Hashimoto M; Mikoshiba K; Weinmaster G; Nakafuku M; Okano H
The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA.
Molecular and cellular biology 2001;21(12):3888-900.
2001: Sawamoto K; Nakao N; Kakishita K; Ogawa Y; Toyama Y; Yamamoto A; Yamaguchi M; Mori K; Goldman S A; Itakura T; Okano H
Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(11):3895-903.
2001: Sawamoto K; Nakao N; Kobayashi K; Matsushita N; Takahashi H; Kakishita K; Yamamoto A; Yoshizaki T; Terashima T; Murakami F; Itakura T; Okano H
Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6423-8.
2001: Mori H; Sakakibara S; Imai T; Nakamura Y; Iijima T; Suzuki A; Yuasa Y; Takeda M; Okano H
Expression of mouse igf2 mRNA-binding protein 3 and its implications for the developing central nervous system.
Journal of neuroscience research 2001;64(2):132-43.
2001: Toda M; Iizuka Y; Yu W; Imai T; Ikeda E; Yoshida K; Kawase T; Kawakami Y; Okano H; Uyemura K
Expression of the neural RNA-binding protein Musashi1 in human gliomas.
Glia 2001;34(1):1-7.
2001: Akamatsu W; Okano H
[Neural stem cell, as a source of graft material for transplantation in neuronal disease]
No to hattatsu. Brain and development 2001;33(2):114-20.
2001: Kishi N; Tang Z; Maeda Y; Hirai A; Mo R; Ito M; Suzuki S; Nakao K; Kinoshita T; Kadesch T; Hui C; Artavanis-Tsakonas S; Okano H; Matsuno K
Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2001;19(1):21-35.
2001: Kawaguchi A; Miyata T; Sawamoto K; Takashita N; Murayama A; Akamatsu W; Ogawa M; Okabe M; Tano Y; Goldman S A; Okano H
Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells.
Molecular and cellular neurosciences 2001;17(2):259-73.
2001: Oishi I; Iwai K; Kagohashi Y; Fujimoto H; Kariya K; Kataoka T; Sawa H; Okano H; Otani H; Yamamura H; Minami Y
Critical role of Caenorhabditis elegans homologs of Cds1 (Chk2)-related kinases in meiotic recombination.
Molecular and cellular biology 2001;21(4):1329-35.
2001: Hisahara S; Yuan J; Momoi T; Okano H; Miura M
Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination.
The Journal of experimental medicine 2001;193(1):111-22.
2000: Yoda A; Sawa H; Okano H
MSI-1, a neural RNA-binding protein, is involved in male mating behaviour in Caenorhabditis elegans.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(11):885-895.
2000: Okano H; Hirano T; Balaban E
Learning and memory.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12403-4.
2000: Sawa H; Kouike H; Okano H
Components of the SWI/SNF complex are required for asymmetric cell division in C. elegans.
Molecular cell 2000;6(3):617-24.
2000: Okano H
[Neural stem cells]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(13 Suppl):2063-77.
2000: Shibata M; Hisahara S; Hara H; Yamawaki T; Fukuuchi Y; Yuan J; Okano H; Miura M
Caspases determine the vulnerability of oligodendrocytes in the ischemic brain.
The Journal of clinical investigation 2000;106(5):643-53.
2000: Araki T; Shibata M; Takano R; Hisahara S; Imamura S i; Fukuuchi Y; Saruta T; Okano H; Miura M
Conditional expression of anti-apoptotic protein p35 by Cre-mediated DNA recombination in cardiomyocytes from loxP-p35-transgenic mice.
Cell death and differentiation 2000;7(5):485-92.
2000: Takano R; Hisahara S; Namikawa K; Kiyama H; Okano H; Miura M
Nerve growth factor protects oligodendrocytes from tumor necrosis factor-alpha-induced injury through Akt-mediated signaling mechanisms.
The Journal of biological chemistry 2000;275(21):16360-5.
2000: Jin M H; Sawamoto K; Ito M; Okano H
The interaction between the Drosophila secreted protein argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted spitz to the receptor.
Molecular and cellular biology 2000;20(6):2098-107.
2000: Hisahara S; Araki T; Sugiyama F; Yagami K i; Suzuki M; Abe K; Yamamura K; Miyazaki J; Momoi T; Saruta T; Bernard C C; Okano H; Miura M
Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination.
The EMBO journal 2000;19(3):341-8.
2000: Ohtani T; Ishihara K; Atsumi T; Nishida K; Kaneko Y; Miyata T; Itoh S; Narimatsu M; Maeda H; Fukada T; Itoh M; Okano H; Hibi M; Hirano T
Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses.
Immunity 2000;12(1):95-105.
2000: Tabuchi K; Sawamoto K; Suzuki E; Ozaki K; Sone M; Hama C; Tanifuji-Morimoto T; Yuasa Y; Yoshihara Y; Nose A; Okano H
GAL4/UAS-WGA system as a powerful tool for tracing Drosophila transsynaptic neural pathways.
Journal of neuroscience research 2000;59(1):94-9.
2000: Igaki T; Kanuka H; Inohara N; Sawamoto K; Núñez G; Okano H; Miura M
Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):662-7.
2000: Nakamura Y; Sakakibara S i; Miyata T; Ogawa M; Shimazaki T; Weiss S; Kageyama R; Okano H
The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(1):283-93.
2000: Hisahara S; Takano R; Shoji S; Okano H; Miura M
Role of caspase-1 subfamily in cytotoxic cytokine-induced oligodendrocyte cell death.
Journal of neural transmission. Supplementum 2000;(58):135-42.
2000: Kaneko Y; Sakakibara S; Imai T; Suzuki A; Nakamura Y; Sawamoto K; Ogawa Y; Toyama Y; Miyata T; Okano H
Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells.
Developmental neuroscience 2000;22(1-2):139-53.
1999: Kanuka H; Sawamoto K; Inohara N; Matsuno K; Okano H; Miura M
Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator.
Molecular cell 1999;4(5):757-69.
1999: Fujimoto J; Sawamoto K; Okabe M; Takagi Y; Tezuka T; Yoshikawa S; Ryo H; Okano H; Yamamoto T
Cloning and characterization of Dfak56, a homolog of focal adhesion kinase, in Drosophila melanogaster.
The Journal of biological chemistry 1999;274(41):29196-201.
1999: Hirota Y; Okabe M; Imai T; Kurusu M; Yamamoto A; Miyao S; Nakamura M; Sawamoto K; Okano H
Musashi and seven in absentia downregulate Tramtrack through distinct mechanisms in Drosophila eye development.
Mechanisms of development 1999;87(1-2):93-101.
1999: Akamatsu W; Okano H J; Osumi N; Inoue T; Nakamura S; Sakakibara S; Miura M; Matsuo N; Darnell R B; Okano H
Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9885-90.
1999: Akamatsu W; Okano H J; Osumi N; Inoue T; Nakamura S; Sakakibara S; Miura M; Matsuo N; Darnell R B; Okano H
Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9885-90.
1999: Sawamoto K; Winge P; Koyama S; Hirota Y; Yamada C; Miyao S; Yoshikawa S; Jin M H; Kikuchi A; Okano H
The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway.
The Journal of cell biology 1999;146(2):361-72.
1999: Araki T; Saruta T; Okano H; Miura M
Caspase activity is required for nephrogenesis in the developing mouse metanephros.
Experimental cell research 1999;248(2):423-9.
1999: Sawamoto K; Yamada C; Kishida S; Hirota Y; Taguchi A; Kikuchi A; Okano H
Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development.
Oncogene 1999;18(11):1967-74.
1999: Umemori H; Kadowaki Y; Hirosawa K; Yoshida Y; Hironaka K; Okano H; Yamamoto T
Stimulation of myelin basic protein gene transcription by Fyn tyrosine kinase for myelination.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(4):1393-7.
1999: Kanuka H; Hisahara S; Sawamoto K; Shoji S; Okano H; Miura M
Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(1):145-50.
1998: Tabuchi K; Yoshikawa S; Yuasa Y; Sawamoto K; Okano H
A novel Drosophila paired-like homeobox gene related to Caenorhabditis elegans unc-4 is expressed in subsets of postmitotic neurons and epidermal cells.
Neuroscience letters 1998;257(1):49-52.
1998: Okano H; Cyert M S; Ohya Y
Importance of phenylalanine residues of yeast calmodulin for target binding and activation.
The Journal of biological chemistry 1998;273(41):26375-82.
1998: Sawamoto K; Taguchi A; Hirota Y; Yamada C; Jin M H; Okano H
Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway.
Cell death and differentiation 1998;5(4):262-70.
1998: Hisahara S; Kanuka H; Shoji S; Yoshikawa S; Okano H; Miura M
Caenorhabditis elegans anti-apoptotic gene ced-9 prevents ced-3-induced cell death in Drosophila cells.
Journal of cell science 1998;111 ( Pt 6)():667-73.
1997: Sakakibara S; Okano H
Expression of neural RNA-binding proteins in the postnatal CNS: implications of their roles in neuronal and glial cell development.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(21):8300-12.
1997: Fletcher C F; Okano H J; Gilbert D J; Yang Y; Yang C; Copeland N G; Jenkins N A; Darnell R B
Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens.
Genomics 1997;45(2):313-9.
1997: Okano H; Okabe M; Taguchi A; Sawamoto K
Evolutionarily conserved mechanisms regulating neural development: lessons from the development of Drosophila peripheral nervous systems.
Human cell : official journal of Human Cell Research Society 1997;10(3):139-50.
1997: Kume S; Yamamoto A; Inoue T; Muto A; Okano H; Mikoshiba K
Developmental expression of the inositol 1,4,5-trisphosphate receptor and structural changes in the endoplasmic reticulum during oogenesis and meiotic maturation of Xenopus laevis.
Developmental biology 1997;182(2):228-39.
1997: Miura M; Hisahara S; Araki T; Okano H
Execution mechanisms of programmed cell death by caspase (ICE/CED-3) family proteases.
Heart and vessels 1997;Suppl 12():66-70.
1997: Okabe M; Sawamoto K; Imai T; Sakakibara S; Yoshikawa S; Okano H
Intrinsic and extrinsic determinants regulating cell fate decision in developing nervous system.
Developmental neuroscience 1997;19(1):9-16.
1996: Sawamoto K; Okano H
Cell-cell interactions during neural development: multiple types of lateral inhibitions involved in Drosophila eye development.
Neuroscience research 1996;26(3):205-14.
1996: Sawamoto K; Okabe M; Tanimura T; Mikoshiba K; Nishida Y; Okano H
The Drosophila secreted protein Argos regulates signal transduction in the Ras/MAPK pathway.
Developmental biology 1996;178(1):13-22.
1996: Chen J; Chang S; Duncan S A; Okano H J; Fishell G; Aderem A
Disruption of the MacMARCKS gene prevents cranial neural tube closure and results in anencephaly.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6275-9.
1996: Okabe M; Sawamoto K; Okano H
The function of the Drosophila argos gene product in the development of embryonic chordotonal organs.
Developmental biology 1996;175(1):37-49.
1996: Sawamoto K; Okabe M; Tanimura T; Hayashi S; Mikoshiba K; Okano H
argos Is required for projection of photoreceptor axons during optic lobe development in Drosophila.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;205(2):162-71.
1996: Matsumoto M; Nakagawa T; Inoue T; Nagata E; Tanaka K; Takano H; Minowa O; Kuno J; Sakakibara S; Yamada M; Yoneshima H; Miyawaki A; Fukuuchi Y; Furuichi T; Okano H; Mikoshiba K; Noda T
Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.
Nature 1996;379(6561):168-71.
1996: Okano H J; Pfaff D W; Gibbs R B
Expression of EGFR-, p75NGFR-, and PSTAIR (cdc2)-like immunoreactivity by proliferating cells in the adult rat hippocampal formation and forebrain.
Developmental neuroscience 1996;18(3):199-209.
1995: Newman L S; McKeever M O; Okano H J; Darnell R B
Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein.
Cell 1995;82(5):773-83.
1995: Ohnishi Y; Kubo S; Ono Y; Nozaki M; Gonda Y; Okano H; Matsuya T; Matsushiro A; Morita T
Cloning and sequencing of the gene coding for dextranase from Streptococcus salivarius.
Gene 1995;156(1):93-6.
1994: Okano H; Yoshikawa S; Suzuki A; Ueno N; Kaizu M; Okabe M; Takahashi T; Matsumoto M; Sawamoto K; Mikoshiba K
Cloning of a Drosophila melanogaster homologue of the mouse type-I bone morphogenetic proteins-2/-4 receptor: a potential decapentaplegic receptor.
Gene 1994;148(2):203-9.
1994: Sawamoto K; Okano H; Kobayakawa Y; Hayashi S; Mikoshiba K; Tanimura T
The function of argos in regulating cell fate decisions during Drosophila eye and wing vein development.
Developmental biology 1994;164(1):267-76.
1993: Mikoshiba K; Furuichi T; Miyawaki A; Yoshikawa S; Nakade S; Michikawa T; Nakagawa T; Okano H; Kume S; Muto A
Structure and function of inositol 1,4,5-trisphosphate receptor.
Annals of the New York Academy of Sciences 1993;707():178-97.
1993: Okano H J; Pfaff D W; Gibbs R B
RB and Cdc2 expression in brain: correlations with 3H-thymidine incorporation and neurogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(7):2930-8.
1993: Kume S; Muto A; Aruga J; Nakagawa T; Michikawa T; Furuichi T; Nakade S; Okano H; Mikoshiba K
The Xenopus IP3 receptor: structure, function, and localization in oocytes and eggs.
Cell 1993;73(3):555-70.
1993: Yoshikawa S; Miyamoto I; Aruga J; Furuichi T; Okano H; Mikoshiba K
Isolation of a Drosophila gene encoding a head-specific guanylyl cyclase.
Journal of neurochemistry 1993;60(4):1570-3.
1992: Okano H; Hayashi S; Tanimura T; Sawamoto K; Yoshikawa S; Watanabe J; Iwasaki M; Hirose S; Mikoshiba K; Montell C
Regulation of Drosophila neural development by a putative secreted protein.
Differentiation; research in biological diversity 1992;52(1):1-11.
1992: Okano H J; Pfaff D W; Gibbs R B
Role of local environmental factors in determining tissue-specific effects of estrogen: examination of uterine tissues transplanted to brain.
Molecular and cellular endocrinology 1992;87(1-3):179-92.
1992: Mikoshiba K; Furuichi T; Miyawaki A; Yoshikawa S; Maeda N; Niinobe M; Nakade S; Nakagawa T; Okano H; Aruga J
The inositol 1,4,5-trisphosphate receptor.
Ciba Foundation symposium 1992;164():17-29; discussion 29-35.
1992: Mikoshiba K; Furuichi T; Miyawaki A; Yoshikawa S; Nakagawa T; Aruga J; Okano H; Yamada N
Inositol 1,4,5-trisphosphate (IP3) receptors.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():62A-63A.
1991: Nakagawa T; Shiota C; Okano H; Mikoshiba K
Differential localization of alternative spliced transcripts encoding inositol 1,4,5-trisphosphate receptors in mouse cerebellum and hippocampus: in situ hybridization study.
Journal of neurochemistry 1991;57(5):1807-10.
1991: Nakagawa T; Okano H; Furuichi T; Aruga J; Mikoshiba K
The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6244-8.
1991: Aruga J; Okano H; Mikoshiba K
Identification of the new isoforms of mouse myelin basic protein: the existence of exon 5a.
Journal of neurochemistry 1991;56(4):1222-6.
1991: Okano H; Aruga J; Nakagawa T; Shiota C; Mikoshiba K
Myelin basic protein gene and the function of antisense RNA in its repression in myelin-deficient mutant mouse.
Journal of neurochemistry 1991;56(2):560-7.
1991: Mikoshiba K; Okano H; Tamura T; Ikenaka K
Structure and function of myelin protein genes.
Annual review of neuroscience 1991;14():201-17.
1991: Mikoshiba K; Aruga J; Okano H
Molecular biology of myelin basic protein: gene rearrangement and expression of anti-sense RNA in myelin-deficient mutants.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1991;98(1):51-61.
1990: Mikoshiba K; Okano H; Aruga J; Tamura T; Miura M; Ikenaka K; Nakagawa T
Chimeric and molecular genetic analysis of myelin-deficient (shiverer and mld) mutant mice.
Annals of the New York Academy of Sciences 1990;605():166-82.
1988: Okano H; Ikenaka K; Mikoshiba K
Recombination within the upstream gene of duplicated myelin basic protein genes of myelin deficient shimld mouse results in the production of antisense RNA.
The EMBO journal 1988;7(11):3407-12.
1988: Ikenaka K; Furuichi T; Iwasaki Y; Moriguchi A; Okano H; Mikoshiba K
Myelin proteolipid protein gene structure and its regulation of expression in normal and jimpy mutant mice.
Journal of molecular biology 1988;199(4):587-96.
1988: Okano H; Tamura T; Miura M; Aoyama A; Ikenaka K; Oshimura M; Mikoshiba K
Gene organization and transcription of duplicated MBP genes of myelin deficient (shi(mld)) mutant mouse.
The EMBO journal 1988;7(1):77-83.
1987: Mikoshiba K; Okano H; Inoue Y; Fujishiro M; Takamatsu K; Lachapelle F; Baumann N; Tsukada Y
Immunohistochemical, biochemical and electron microscopic analysis of myelin formation in the central nervous system of myelin deficient (mld) mutant mice.
Brain research 1987;432(1):111-21.
1987: Moriguchi A; Ikenaka K; Furuichi T; Okano H; Iwasaki Y; Mikoshiba K
The fifth exon of the myelin proteolipid protein-coding gene is not utilized in the brain of jimpy mutant mice.
Gene 1987;55(2-3):333-7.

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