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Jean Bennett
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36
Maguire, Albert
15
Jacobson, Samuel
14
Aleman, Tomas
14
Cideciyan, Artur
13
Dejneka, Nadine
13
Tang, Waixing
11
Wilson, James
10
Auricchio, Alberto
9
Surace, Enrico
9
Rex, Tonia
7
Anand, Vibha
6
Acland, Gregory
6
Wei, Zhangyong
6
Stone, Edwin
5
Schwartz, Sharon
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All Publications
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2009: Zhang Ying; Singh Manvendra K; Degenhardt Karl R; Lu Min Min; Bennett Jean; Yoshida Yutaka; Epstein Jonathan A
Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects.
Developmental biology 2009;325(1):82-93.
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2008: Allocca Mariacarmela; Doria Monica; Petrillo Marco; Colella Pasqualina; Garcia-Hoyos Maria; Gibbs Daniel; Kim So Ra; Maguire Albert; Rex Tonia S; Di Vicino Umberto; Cutillo Luisa; Sparrow Janet R; Williams David S; Bennett Jean; Auricchio Alberto
Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice.
The Journal of clinical investigation 2008;118(5):1955-64.
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2008: Lebherz Corinna; Maguire Albert; Tang Waixing; Bennett Jean; Wilson James M
Novel AAV serotypes for improved ocular gene transfer.
The journal of gene medicine 2008;10(4):375-82.
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2008: Bennicelli Jeannette; Wright John Fraser; Komaromy Andras; Jacobs Jonathan B; Hauck Bernd; Zelenaia Olga; Mingozzi Federico; Hui Daniel; Chung Daniel; Rex Tonia S; Wei Zhangyong; Qu Guang; Zhou Shangzhen; Zeiss Caroline; Arruda Valder R; Acland Gregory M; Dell'Osso Lou F; High Katherine A; Maguire Albert M; Bennett Jean
Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(3):458-65.
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2007: Bennett Jean
Retinal progenitor cells--timing is everything.
The New England journal of medicine 2007;356(15):1577-9.
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2006: Shindler Kenneth S; Guan Yangtai; Ventura Elvira; Bennett Jean; Rostami Abdolmohamad
Retinal ganglion cell loss induced by acute optic neuritis in a relapsing model of multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2006;12(5):526-32.
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2006: Bedrosian Jeffrey C; Gratton Michael Anne; Brigande John V; Tang Waixing; Landau Jessica; Bennett Jean
In vivo delivery of recombinant viruses to the fetal murine cochlea: transduction characteristics and long-term effects on auditory function.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(3):328-35.
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2006: Jacobson Samuel G; Acland Gregory M; Aguirre Gustavo D; Aleman Tomas S; Schwartz Sharon B; Cideciyan Artur V; Zeiss Caroline J; Komaromy Andras M; Kaushal Shalesh; Roman Alejandro J; Windsor Elizabeth A M; Sumaroka Alexander; Pearce-Kelling Susan E; Conlon Thomas J; Chiodo Vincent A; Boye Sanford L; Flotte Terence R; Maguire Albert M; Bennett Jean; Hauswirth William W
Safety of recombinant adeno-associated virus type 2-RPE65 vector delivered by ocular subretinal injection.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(6):1074-84.
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2006: Zhang Zhibing; Kostetskii Igor; Tang Waixing; Haig-Ladewig Lisa; Sapiro Rossana; Wei Zhangyong; Patel Aatish M; Bennett Jean; Gerton George L; Moss Stuart B; Radice Glenn L; Strauss Jerome F
Deficiency of SPAG16L causes male infertility associated with impaired sperm motility.
Biology of reproduction 2006;74(4):751-9.
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2006: Bennett Jean
Commentary: an aye for eye gene therapy.
Human gene therapy 2006;17(2):177-9.
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2006: Wilson David F; Vinogradov Sergei A; Grosul Pavel; Sund Newman; Vacarezza M Noel; Bennett Jean
Imaging oxygen pressure in the rodent retina by phosphorescence lifetime.
Advances in experimental medicine and biology 2006;578():119-24.
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2005: Bennett Jean
Strategies for delivery of rod-derived cone viability factor.
Retina (Philadelphia, Pa.) 2005;25(8 Suppl):S47.
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2005: Cideciyan Artur V; Swider Malgorzata; Aleman Tomas S; Sumaroka Alexander; Schwartz Sharon B; Roman Marisa I; Milam Ann H; Bennett Jean; Stone Edwin M; Jacobson Samuel G
ABCA4-associated retinal degenerations spare structure and function of the human parapapillary retina.
Investigative ophthalmology & visual science 2005;46(12):4739-46.
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2005: Acland Gregory M; Aguirre Gustavo D; Bennett Jean; Aleman Tomas S; Cideciyan Artur V; Bennicelli Jeannette; Dejneka Nadine S; Pearce-Kelling Susan E; Maguire Albert M; Palczewski Krzysztof; Hauswirth William W; Jacobson Samuel G
Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(6):1072-82.
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2005: Wang Fushan; Tang Waixing; McGraw Helen M; Bennett Jean; Enquist Lynn W; Friedman Harvey M
Herpes simplex virus type 1 glycoprotein e is required for axonal localization of capsid, tegument, and membrane glycoproteins.
Journal of virology 2005;79(21):13362-72.
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2005: Wilson David F; Vinogradov Sergei A; Grosul Pavel; Vaccarezza M Noel; Kuroki Akiko; Bennett Jean
Oxygen distribution and vascular injury in the mouse eye measured by phosphorescence-lifetime imaging.
Applied optics 2005;44(25):5239-48.
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2005: Zhang Zhibing; Jones Brian H; Tang Waixing; Moss Stuart B; Wei Zhangyong; Ho Clement; Pollack Michael; Horowitz Eran; Bennett Jean; Baker Michael E; Strauss Jerome F
Dissecting the axoneme interactome: the mammalian orthologue of Chlamydomonas PF6 interacts with sperm-associated antigen 6, the mammalian orthologue of Chlamydomonas PF16.
Molecular & cellular proteomics : MCP 2005;4(7):914-23.
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2005: Hahn Paul; Lindsten Tullia; Tolentino Michael; Thompson Craig B; Bennett Jean; Dunaief Joshua L
Persistent fetal ocular vasculature in mice deficient in bax and bak.
Archives of ophthalmology 2005;123(6):797-802.
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2005: Jacobson Samuel G; Aleman Tomas S; Cideciyan Artur V; Sumaroka Alexander; Schwartz Sharon B; Windsor Elizabeth A M; Traboulsi Elias I; Heon Elise; Pittler Steven J; Milam Ann H; Maguire Albert M; Palczewski Krzysztof; Stone Edwin M; Bennett Jean
Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(17):6177-82.
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2005: Lebherz Corinna; Maguire Albert M; Auricchio Alberto; Tang Waixing; Aleman Tomas S; Wei Zhangyong; Grant Rebecca; Cideciyan Artur V; Jacobson Samuel G; Wilson James M; Bennett Jean
Nonhuman primate models for diabetic ocular neovascularization using AAV2-mediated overexpression of vascular endothelial growth factor.
Diabetes 2005;54(4):1141-9.
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2005: Lebherz Corinna; Auricchio Alberto; Maguire Albert M; Rivera Victor M; Tang Waixing; Grant Rebecca L; Clackson Tim; Bennett Jean; Wilson James M
Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates.
Human gene therapy 2005;16(2):178-86.
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2005: Schwartz Sharon B; Aleman Tomas S; Cideciyan Artur V; Windsor Elizabeth A M; Sumaroka Alexander; Roman Alejandro J; Rane Tej; Smilko Elaine E; Bennett Jean; Stone Edwin M; Kimberling William J; Liu Xue-Zhong; Jacobson Samuel G
Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.
Investigative ophthalmology & visual science 2005;46(2):734-43.
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2005: Wilson David F; Vinogradov Sergei A; Grosul Pavel; Kuroki Akiko; Bennett Jean
Imaging oxygen pressure in the retina of the mouse eye.
Advances in experimental medicine and biology 2005;566():159-65.
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2005: Rex Tonia S; Peet John A; Surace Enrico M; Calvert Peter D; Nikonov Sergei S; Lyubarsky Arkady L; Bendo Elisabeth; Hughes Thomas; Pugh E N; Bennett Jean
The distribution, concentration, and toxicity of enhanced green fluorescent protein in retinal cells after genomic or somatic (virus-mediated) gene transfer.
Molecular vision 2005;11():1236-45.
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2005: Keiser Nicholas W; Tang Waixing; Wei Zhangyong; Bennett Jean
Spatial and temporal expression patterns of the choroideremia gene in the mouse retina.
Molecular vision 2005;11():1052-60.
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2004: Schuettauf Frank; Vorwerk Christian; Naskar Rita; Orlin Anton; Quinto Kristine; Zurakowski David; Dejneka Nadine S; Klein Ronald L; Meyer Edward M; Bennett Jean
Adeno-associated viruses containing bFGF or BDNF are neuroprotective against excitotoxicity.
Current eye research 2004;29(6):379-86.
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2004: Dejneka Nadine S; Kuroki Akiko M; Fosnot Joshua; Tang Waixing; Tolentino Michael J; Bennett Jean
Systemic rapamycin inhibits retinal and choroidal neovascularization in mice.
Molecular vision 2004;10():964-72.
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2004: Wong Wai T; Rex Tonia S; Auricchio Alberto; Maguire Albert M; Chung Daniel; Tang Waixing; Bennett Jean
Effect of over-expression of pigment epithelium derived factor (PEDF) on developing retinal vasculature in the mouse.
Molecular vision 2004;10():837-44.
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2004: Rex Tonia S; Allocca Mariacarmela; Domenici Luciano; Surace Enrico M; Maguire Albert M; Lyubarsky Arkady; Cellerino Alessandro; Bennett Jean; Auricchio Alberto
Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(5):855-61.
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2004: Rex T S; Tsui I; Hahn P; Maguire A M; Duan D; Bennett J; Dunaief J L
Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress.
Human gene therapy 2004;15(10):960-7.
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2004: Chen Lin; Wu Wayne; Dentchev Tzvete; Zeng Yong; Wang Jianhua; Tsui Irena; Tobias John W; Bennett Jean; Baldwin Donald; Dunaief Joshua L
Light damage induced changes in mouse retinal gene expression.
Experimental eye research 2004;79(2):239-47.
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2004: Aleman Tomas S; Jacobson Samuel G; Chico John D; Scott Michele L; Cheung Andy Y; Windsor Elizabeth A M; Furushima Masatoshi; Redmond T Michael; Bennett Jean; Palczewski Krzysztof; Cideciyan Artur V
Impairment of the transient pupillary light reflex in Rpe65(-/-) mice and humans with leber congenital amaurosis.
Investigative ophthalmology & visual science 2004;45(4):1259-71.
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2004: Cideciyan Artur V; Aleman Tomas S; Swider Malgorzata; Schwartz Sharon B; Steinberg Janet D; Brucker Alexander J; Maguire Albert M; Bennett Jean; Stone Edwin M; Jacobson Samuel G
Mutations in ABCA4 result in accumulation of lipofuscin before slowing of the retinoid cycle: a reappraisal of the human disease sequence.
Human molecular genetics 2004;13(5):525-34.
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2004: Dejneka Nadine S; Surace Enrico M; Aleman Tomas S; Cideciyan Artur V; Lyubarsky Arkady; Savchenko Andrey; Redmond T Michael; Tang Waixing; Wei Zhangyong; Rex Tonia S; Glover Ernest; Maguire Albert M; Pugh Edward N; Jacobson Samuel G; Bennett Jean
In utero gene therapy rescues vision in a murine model of congenital blindness.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(2):182-8.
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2004: Bennett Jean
Gene therapy for Leber congenital amaurosis.
Novartis Foundation symposium 2004;255():195-202; discussion 202-7.
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2003: Hahn Paul; Lindsten Tullia; Ying Gui-Shuang; Bennett Jean; Milam Ann H; Thompson Craig B; Dunaief Joshua L
Proapoptotic bcl-2 family members, Bax and Bak, are essential for developmental photoreceptor apoptosis.
Investigative ophthalmology & visual science 2003;44(8):3598-605.
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2003: Surace Enrico M; Auricchio Alberto; Reich Samuel J; Rex Tonia; Glover Ernest; Pineles Stacey; Tang Waixing; O'Connor Erin; Lyubarsky Arkady; Savchenko Andrey; Pugh Edward N; Maguire Albert M; Wilson James M; Bennett Jean
Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transduction.
Journal of virology 2003;77(14):7957-63.
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2003: Reich Samuel J; Bennett Jean
Gene therapy for ocular neovascularization: a cure in sight.
Current opinion in genetics & development 2003;13(3):317-22.
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2003: Bennett J
Immune response following intraocular delivery of recombinant viral vectors.
Gene therapy 2003;10(11):977-82.
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2003: Reich Samuel J; Fosnot Joshua; Kuroki Akiko; Tang Waixing; Yang Xiangyang; Maguire Albert M; Bennett Jean; Tolentino Michael J
Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.
Molecular vision 2003;9():210-6.
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2003: Chen Lin; Dentchev Tzvete; Wong Robert; Hahn Paul; Wen Rong; Bennett Jean; Dunaief Joshua L
Increased expression of ceruloplasmin in the retina following photic injury.
Molecular vision 2003;9():151-8.
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2003: Anand Vibha; Barral Duarte C; Zeng Yong; Brunsmann Frank; Maguire Albert M; Seabra Miguel C; Bennett Jean
Gene therapy for choroideremia: in vitro rescue mediated by recombinant adenovirus.
Vision research 2003;43(8):919-26.
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2003: Reich S J; Auricchio A; Hildinger M; Glover E; Maguire A M; Wilson J M; Bennett J
Efficient trans-splicing in the retina expands the utility of adeno-associated virus as a vector for gene therapy.
Human gene therapy 2003;14(1):37-44.
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2003: Liang Fong-Qi; Surace Enrico; Dejneka Nadine S; Maguire Albert M; Bennett Jean
Müller cell transduction by AAV2 in normal and degenerative retinas.
Advances in experimental medicine and biology 2003;533():439-45.
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2003: Dejneka Nadine S; Surace Enrico M; Bennett Jean
Gene therapy for Leber congenital amaurosis.
Advances in experimental medicine and biology 2003;533():415-22.
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2003: Dejneka Nadine S; Rex Tonia S; Bennett Jean
Gene therapy and animal models for retinal disease.
Developments in ophthalmology 2003;37():188-98.
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2002: Behling K C; Surace E M; Bennett J
Pigment epithelium-derived factor expression in the developing mouse eye.
Molecular vision 2002;8():449-54.
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2002: Ho Thucanh T; Maguire Albert M; Aguirre Gustavo D; Surace Enrico M; Anand Vibha; Zeng Yong; Salvetti Anna; Hopwood John J; Haskins Mark E; Bennett Jean
Phenotypic rescue after adeno-associated virus-mediated delivery of 4-sulfatase to the retinal pigment epithelium of feline mucopolysaccharidosis VI.
The journal of gene medicine 2002;4(6):613-21.
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2002: Auricchio Alberto; Behling Kathryn C; Maguire Albert M; O'Connor Erin M; Bennett Jean; Wilson James M; Tolentino Michael J
Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(4):490-4.
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2002: Duncan Jacque L; Aleman Tomas S; Gardner Leigh M; De Castro Elaine; Marks Daniel A; Emmons Jessica M; Bieber Michelle L; Steinberg Janet D; Bennett Jean; Stone Edwin M; MacDonald Ian M; Cideciyan Artur V; Maguire Maureen G; Jacobson Samuel G
Macular pigment and lutein supplementation in choroideremia.
Experimental eye research 2002;74(3):371-81.
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2002: Anand Vibha; Duffy Bethany; Yang Zaixin; Dejneka Nadine S; Maguire Albert M; Bennett Jean
A deviant immune response to viral proteins and transgene product is generated on subretinal administration of adenovirus and adeno-associated virus.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(2):125-32.
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2001: Auricchio A; Kobinger G; Anand V; Hildinger M; O'Connor E; Maguire A M; Wilson J M; Bennett J
Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model.
Human molecular genetics 2001;10(26):3075-81.
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2001: Liang F Q; Aleman T S; Dejneka N S; Dudus L; Fisher K J; Maguire A M; Jacobson S G; Bennett J
Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosa.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(5):461-72.
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2001: Dejneka N S; Bennett J
Gene therapy and retinitis pigmentosa: advances and future challenges.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(7):662-8.
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2001: Karakousis P C; John S K; Behling K C; Surace E M; Smith J E; Hendrickson A; Tang W X; Bennett J; Milam A H
Localization of pigment epithelium derived factor (PEDF) in developing and adult human ocular tissues.
Molecular vision 2001;7():154-63.
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2001: Gupta A R; Dejneka N S; D'Amato R J; Yang Z; Syed N; Maguire A M; Bennett J
Strain-dependent anterior segment neovascularization following intravitreal gene transfer of basic fibroblast growth factor (bFGF).
The journal of gene medicine 2001;3(3):252-9.
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2001: Acland G M; Aguirre G D; Ray J; Zhang Q; Aleman T S; Cideciyan A V; Pearce-Kelling S E; Anand V; Zeng Y; Maguire A M; Jacobson S G; Hauswirth W W; Bennett J
Gene therapy restores vision in a canine model of childhood blindness.
Nature genetics 2001;28(1):92-5.
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2001: Liang F Q; Aleman T S; ZaixinYang; Cideciyan A V; Jacobson S G; Bennett J
Melatonin delays photoreceptor degeneration in the rds/rds mouse.
Neuroreport 2001;12(5):1011-4.
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2001: Dejneka N S; Auricchio A; Maguire A M; Ye X; Gao G P; Wilson J M; Bennett J
Pharmacologically regulated gene expression in the retina following transduction with viral vectors.
Gene therapy 2001;8(6):442-6.
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2001: Liang F Q; Dejneka N S; Cohen D R; Krasnoperova N V; Lem J; Maguire A M; Dudus L; Fisher K J; Bennett J
AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(2):241-8.
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2000: Bennett J
Gene therapy for retinitis pigmentosa.
Current opinion in molecular therapeutics 2000;2(4):420-5.
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2000: Bennett J; Maguire A M
Gene therapy for ocular disease.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(6):501-5.
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2000: Jacobson S G; Cideciyan A V; Iannaccone A; Weleber R G; Fishman G A; Maguire A M; Affatigato L M; Bennett J; Pierce E A; Danciger M; Farber D B; Stone E M
Disease expression of RP1 mutations causing autosomal dominant retinitis pigmentosa.
Investigative ophthalmology & visual science 2000;41(7):1898-908.
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2000: Anand V; Chirmule N; Fersh M; Maguire A M; Bennett J
Additional transduction events after subretinal readministration of recombinant adeno-associated virus.
Human gene therapy 2000;11(3):449-57.
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2000: Bennett J; Anand V; Acland G M; Maguire A M
Cross-species comparison of in vivo reporter gene expression after recombinant adeno-associated virus-mediated retinal transduction.
Methods in enzymology 2000;316():777-89.
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2000: Bennett J; Zeng Y; Gupta A R; Maguire A M
Application of adenoviral vectors. Analysis of eye development.
Methods in molecular biology (Clifton, N.J.) 2000;135():525-35.
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1999: Dreyer E B; Vorwerk C K; Zurakowski D; Simon P D; Bennett J
Infection with adeno-associated virus may protect against excitotoxicity.
Neuroreport 1999;10(14):2887-90.
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1999: Bennett J; Maguire A M; Cideciyan A V; Schnell M; Glover E; Anand V; Aleman T S; Chirmule N; Gupta A R; Huang Y; Gao G P; Nyberg W C; Tazelaar J; Hughes J; Wilson J M; Jacobson S G
Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9920-5.
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1999: Simon P D; Vorwerk C K; Mansukani S S; Chen S J; Wilson J M; Zurakowski D; Bennett J; Dreyer E B
bcl-2 gene therapy exacerbates excitotoxicity.
Human gene therapy 1999;10(10):1715-20.
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1999: Dudus L; Anand V; Acland G M; Chen S J; Wilson J M; Fisher K J; Maguire A M; Bennett J
Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV.
Vision research 1999;39(15):2545-53.
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1998: Bennett J; Zeng Y; Bajwa R; Klatt L; Li Y; Maguire A M
Adenovirus-mediated delivery of rhodopsin-promoted bcl-2 results in a delay in photoreceptor cell death in the rd/rd mouse.
Gene therapy 1998;5(9):1156-64.
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1998: Zeng Y; Rosborough R C; Li Y; Gupta A R; Bennett J
Temporal and spatial regulation of gene expression mediated by the promoter for the human tissue inhibitor of metalloproteinases-3 (TIMP-3)-encoding gene.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;211(3):228-37.
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1997: Bennett J; Duan D; Engelhardt J F; Maguire A M
Real-time, noninvasive in vivo assessment of adeno-associated virus-mediated retinal transduction.
Investigative ophthalmology & visual science 1997;38(13):2857-63.
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1997: Hoffman L M; Maguire A M; Bennett J
Cell-mediated immune response and stability of intraocular transgene expression after adenovirus-mediated delivery.
Investigative ophthalmology & visual science 1997;38(11):2224-33.
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1996: Bennett J; Tanabe T; Sun D; Zeng Y; Kjeldbye H; Gouras P; Maguire A M
Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy.
Nature medicine 1996;2(6):649-54.
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1995: Bennett J; Sun D; Karikó K
Sequence analysis of the 5.34-kb 5' flanking region of the human rhodopsin-encoding gene.
Gene 1995;167(1-2):317-20.
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1995: Budenz D L; Bennett J; Alonso L; Maguire A
In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells.
Investigative ophthalmology & visual science 1995;36(11):2211-5.
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1994: Bennett J; Wilson J; Sun D; Forbes B; Maguire A
Adenovirus vector-mediated in vivo gene transfer into adult murine retina.
Investigative ophthalmology & visual science 1994;35(5):2535-42.
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