Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Allan Okey

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Anatomy

Living Beings

Physiology

Enzyme Induction

Procedures

Disorders

Experimental Liver Neoplasms

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
23
Harper, Patricia
15
Boutros, Paul
15
Pohjanvirta, Raimo
10
Moffat, Ivy
8
Tuomisto, Jouko
7
Prokipcak, RD
7
Denison, Michael
7
Giannone, JV
6
Franc, Monique
5
Roberts, Eve
4
Li, Wei
4
Riddick, David
4
Wong, JM
3
Tijet, Nathalie
3
Lindén, Jere

Sign-in to see all Coauthors

Publications

TOP 3
Celius Trine; Roblin Steven; Harper Patricia A; Matthews Jason; Boutros Paul C; Pohjanvirta Raimo; Okey Allan B
Aryl hydrocarbon receptor-dependent induction of flavin-containing monooxygenase mRNAs in mouse liver.
Cotterchio Michelle; Boucher Beatrice A; Manno Michael; Gallinger Steven; Okey Allan B; Harper Patricia A
Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk.
Franc Monique A; Moffat Ivy D; Boutros Paul C; Tuomisto Jouni T; Tuomisto Jouko; Pohjanvirta Raimo; Okey Allan B
Patterns of dioxin-altered mRNA expression in livers of dioxin-sensitive versus dioxin-resistant rats.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Allan Okey (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2008: Celius Trine; Roblin Steven; Harper Patricia A; Matthews Jason; Boutros Paul C; Pohjanvirta Raimo; Okey Allan B
Aryl hydrocarbon receptor-dependent induction of flavin-containing monooxygenase mRNAs in mouse liver.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(12):2499-505.
2008: Cotterchio Michelle; Boucher Beatrice A; Manno Michael; Gallinger Steven; Okey Allan B; Harper Patricia A
Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(11):3098-107.
2008: Franc Monique A; Moffat Ivy D; Boutros Paul C; Tuomisto Jouni T; Tuomisto Jouko; Pohjanvirta Raimo; Okey Allan B
Patterns of dioxin-altered mRNA expression in livers of dioxin-sensitive versus dioxin-resistant rats.
Archives of toxicology 2008;82(11):809-30.
2008: Pohjanvirta Raimo; Boutros Paul C; Moffat Ivy D; Lindén Jere; Wendelin Dominique; Okey Allan B
Genome-wide effects of acute progressive feed restriction in liver and white adipose tissue.
Toxicology and applied pharmacology 2008;230(1):41-56.
2008: Boutros Paul C; Yan Rui; Moffat Ivy D; Pohjanvirta Raimo; Okey Allan B
Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: comparison of rat and mouse.
BMC genomics 2008;9():419.
2007: Moffat Ivy D; Boutros Paul C; Celius Trine; Lindén Jere; Pohjanvirta Raimo; Okey Allan B
microRNAs in adult rodent liver are refractory to dioxin treatment.
Toxicological sciences : an official journal of the Society of Toxicology 2007;99(2):470-87.
2007: Moffat Ivy D; Roblin Steven; Harper Patricia A; Okey Allan B; Pohjanvirta Raimo
Aryl hydrocarbon receptor splice variants in the dioxin-resistant rat: tissue expression and transactivational activity.
Molecular pharmacology 2007;72(4):956-66.
2007: Okey Allan B
An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI.
Toxicological sciences : an official journal of the Society of Toxicology 2007;98(1):5-38.
2006: Cotterchio Michelle; Boucher Beatrice A; Manno Michael; Gallinger Steven; Okey Allan; Harper Patricia
Dietary phytoestrogen intake is associated with reduced colorectal cancer risk.
The Journal of nutrition 2006;136(12):3046-53.
2006: Semeralul Mawahib O; Boutros Paul C; Likhodi Olga; Okey Allan B; Van Tol Hubert H M; Wong Albert H C
Microarray analysis of the developing cortex.
Journal of neurobiology 2006;66(14):1646-58.
2006: Reiner Eric J; Clement Ray E; Okey Allan B; Marvin Chris H
Advances in analytical techniques for polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like PCBs.
Analytical and bioanalytical chemistry 2006;386(4):791-806.
2006: Harper Patricia A; Riddick David S; Okey Allan B
Regulating the regulator: factors that control levels and activity of the aryl hydrocarbon receptor.
Biochemical pharmacology 2006;72(3):267-79.
2006: Pastorelli Roberta; Carpi Donatella; Campagna Roberta; Airoldi Luisa; Pohjanvirta Raimo; Viluksela Matti; Hakansson Helen; Boutros Paul C; Moffat Ivy D; Okey Allan B; Fanelli Roberto
Differential expression profiling of the hepatic proteome in a rat model of dioxin resistance: correlation with genomic and transcriptomic analyses.
Molecular & cellular proteomics : MCP 2006;5(5):882-94.
2006: Pohjanvirta Raimo; Niittynen Marjo; Lindén Jere; Boutros Paul C; Moffat Ivy D; Okey Allan B
Evaluation of various housekeeping genes for their applicability for normalization of mRNA expression in dioxin-treated rats.
Chemico-biological interactions 2006;160(2):134-49.
2006: Tijet Nathalie; Boutros Paul C; Moffat Ivy D; Okey Allan B; Tuomisto Jouko; Pohjanvirta Raimo
Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries.
Molecular pharmacology 2006;69(1):140-53.
2005: Boutros Paul C; Okey Allan B
Unsupervised pattern recognition: an introduction to the whys and wherefores of clustering microarray data.
Briefings in bioinformatics 2005;6(4):331-43.
2005: Okey Allan B; Franc Monique A; Moffat Ivy D; Tijet Nathalie; Boutros Paul C; Korkalainen Merja; Tuomisto Jouko; Pohjanvirta Raimo
Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: the case of the aryl hydrocarbon receptor.
Toxicology and applied pharmacology 2005;207(2 Suppl):43-51.
2005: Séguin Béatrice; Boutros Paul C; Li Xujian; Okey Allan B; Uetrecht Jack P
Gene expression profiling in a model of D-penicillamine-induced autoimmunity in the Brown Norway rat: predictive value of early signs of danger.
Chemical research in toxicology 2005;18(8):1193-202.
2005: Okey Allan B; Boutros Paul C; Harper Patricia A
Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes.
Pharmacogenetics and genomics 2005;15(6):371-9.
2004: Boutros Paul C; Okey Allan B
PUNS: transcriptomic- and genomic-in silico PCR for enhanced primer design.
Bioinformatics (Oxford, England) 2004;20(15):2399-400.
2004: Boutros Paul C; Moffat Ivy D; Franc Monique A; Tijet Nathalie; Tuomisto Jouko; Pohjanvirta Raimo; Okey Allan B
Dioxin-responsive AHRE-II gene battery: identification by phylogenetic footprinting.
Biochemical and biophysical research communications 2004;321(3):707-15.
2004: Nebert Daniel W; Dalton Timothy P; Okey Allan B; Gonzalez Frank J
Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer.
The Journal of biological chemistry 2004;279(23):23847-50.
2004: Roblin Steven; Okey Allan B; Harper Patricia A
AH receptor antagonist inhibits constitutive CYP1A1 and CYP1B1 expression in rat BP8 cells.
Biochemical and biophysical research communications 2004;317(1):142-8.
2002: Harper Patricia A; Wong Judy m Y; Lam Maria S M; Okey Allan B
Polymorphisms in the human AH receptor.
Chemico-biological interactions 2002;141(1-2):161-87.
2002: Sy Sherwin K B; Ciaccia Antonio; Li Wei; Roberts Eve A; Okey Allan; Kalow Werner; Tang Bing-Kou
Modeling of human hepatic CYP3A4 enzyme kinetics, protein, and mRNA indicates deviation from log-normal distribution in CYP3A4 gene expression.
European journal of clinical pharmacology 2002;58(5):357-65.
2001: Ozdemir V; Kalow W; Okey A B; Lam M S; Albers L J; Reist C; Fourie J; Posner P; Collins E J; Roy R
Treatment-resistance to clozapine in association with ultrarapid CYP1A2 activity and the C-->A polymorphism in intron 1 of the CYP1A2 gene: effect of grapefruit juice and low-dose fluvoxamine.
Journal of clinical psychopharmacology 2001;21(6):603-7.
2001: Franc M A; Pohjanvirta R; Tuomisto J; Okey A B
In vivo up-regulation of aryl hydrocarbon receptor expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a dioxin-resistant rat model.
Biochemical pharmacology 2001;62(12):1565-78.
2001: Wong J M; Okey A B; Harper P A
Human aryl hydrocarbon receptor polymorphisms that result in loss of CYP1A1 induction.
Biochemical and biophysical research communications 2001;288(4):990-6.
2001: Franc M A; Pohjanvirta R; Tuomisto J; Okey A B
Persistent, low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effect on aryl hydrocarbon receptor expression in a dioxin-resistance model.
Toxicology and applied pharmacology 2001;175(1):43-53.
2001: Wong J M; Harper P A; Meyer U A; Bock K W; Morike K; Lagueux J; Ayotte P; Tyndale R F; Sellers E M; Manchester D K; Okey A B
Ethnic variability in the allelic distribution of human aryl hydrocarbon receptor codon 554 and assessment of variant receptor function in vitro.
Pharmacogenetics 2001;11(1):85-94.
2000: Iba M M; Fung J; Giannone J V; Okey A B
Comparative induction of CYP1A1 expression by pyridine and its metabolites.
Archives of biochemistry and biophysics 2000;378(2):299-310.
1999: Pohjanvirta R; Viluksela M; Tuomisto J T; Unkila M; Karasinska J; Franc M A; Holowenko M; Giannone J V; Harper P A; Tuomisto J; Okey A B
Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains.
Toxicology and applied pharmacology 1999;155(1):82-95.
1998: Li W; Harper P A; Tang B K; Okey A B
Regulation of cytochrome P450 enzymes by aryl hydrocarbon receptor in human cells: CYP1A2 expression in the LS180 colon carcinoma cell line after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or 3-methylcholanthrene.
Biochemical pharmacology 1998;56(5):599-612.
1998: Pohjanvirta R; Wong J M; Li W; Harper P A; Tuomisto J; Okey A B
Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant rat strain.
Molecular pharmacology 1998;54(1):86-93.
1998: Giannone J V; Li W; Probst M; Okey A B
Prolonged depletion of AH receptor without alteration of receptor mRNA levels after treatment of cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Biochemical pharmacology 1998;55(4):489-97.
1997: Okey A B; Giannone J V; Smart W; Wong J M; Manchester D K; Parker N B; Feeley M M; Grant D L; Gilman A
Binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to AH receptor in placentas from normal versus abnormal pregnancy outcomes.
Chemosphere 1997;34(5-7):1535-47.
1995: Okey A B; Riddick D S; Harper P A
Ah receptor role in TCDD toxicity: still some mysteries but no myth--a reply to the commentary by Dr. L.W.D. Weber and Dr. B.U. Stahl.
Toxicology letters 1995;75(1-3):249-54.
1995: Giannone J V; Okey A B; Harper P A
Characterization of polyclonal antibodies to the aromatic hydrocarbon receptor.
Canadian journal of physiology and pharmacology 1995;73(1):7-17.
1995: Huang Y; Harper P A; Okey A B
Aromatic hydrocarbon receptor in cultured fetal cells from C57BL/6J and DBA/2J mice: similarity in molecular mass to receptors in adult livers.
Canadian journal of physiology and pharmacology 1995;73(1):18-26.
1994: Okey A B; Riddick D S; Harper P A
Molecular biology of the aromatic hydrocarbon (dioxin) receptor.
Trends in pharmacological sciences 1994;15(7):226-32.
1994: de Morais S M; Giannone J V; Okey A B
Photoaffinity labeling of the Ah receptor with 3-[3H]methylcholanthrene and formation of a 165-kDa complex between the ligand-binding subunit and a novel cytosolic protein.
The Journal of biological chemistry 1994;269(16):12129-36.
1994: Riddick D S; Huang Y; Harper P A; Okey A B
2,3,7,8-Tetrachlorodibenzo-p-dioxin versus 3-methylcholanthrene: comparative studies of Ah receptor binding, transformation, and induction of CYP1A1.
The Journal of biological chemistry 1994;269(16):12118-28.
1994: Okey A B; Riddick D S; Harper P A
The Ah receptor: mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds.
Toxicology letters 1994;70(1):1-22.
1993: Jellinck P H; Forkert P G; Riddick D S; Okey A B; Michnovicz J J; Bradlow H L
Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation.
Biochemical pharmacology 1993;45(5):1129-36.
1992: Harper P A; Giannone J V; Okey A B; Denison M S
In vitro transformation of the human Ah receptor and its binding to a dioxin response element.
Molecular pharmacology 1992;42(4):603-12.
1991: Harper P A; Golas C L; Okey A B
Ah receptor in mice genetically "nonresponsive" for cytochrome P4501A1 induction: cytosolic Ah receptor, transformation to the nuclear binding state, and induction of aryl hydrocarbon hydroxylase by halogenated and nonhalogenated aromatic hydrocarbons in embryonic tissues and cells.
Molecular pharmacology 1991;40(5):818-26.
1991: Harper P A; Prokipcak R D; Bush L E; Golas C L; Okey A B
Detection and characterization of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the human colon adenocarcinoma cell line LS180.
Archives of biochemistry and biophysics 1991;290(1):27-36.
1991: Prokipcak R D; Okey A B
Downregulation of the Ah receptor in mouse hepatoma cells treated in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Canadian journal of physiology and pharmacology 1991;69(8):1204-10.
1991: Lorenzen A; Okey A B
Detection and characterization of Ah receptor in tissue and cells from human tonsils.
Toxicology and applied pharmacology 1991;107(2):203-14.
1990: Prokipcak R D; Denison M S; Okey A B
Nuclear Ah receptor from mouse hepatoma cells: effect of partial proteolysis on relative molecular mass and DNA-binding properties.
Archives of biochemistry and biophysics 1990;283(2):476-83.
1990: Lorenzen A; Okey A B
Detection and characterization of [3H]2,3,7,8-tetrachlorodibenzo-p-dioxin binding to Ah receptor in a rainbow trout hepatoma cell line.
Toxicology and applied pharmacology 1990;106(1):53-62.
1990: Prokipcak R D; Okey A B
Equivalent molecular mass of cytosolic and nuclear forms of Ah receptor from Hepa-1 cells determined by photoaffinity labeling with 2,3,7,8-[3H]tetrachlorodibenzo-p-dioxin.
Biochemical and biophysical research communications 1990;172(2):698-704.
1990: Golas C L; Prokipcak R D; Okey A B; Manchester D K; Safe S; Fujita T
Competitive binding of 7-substituted-2,3-dichlorodibenzo-p-dioxins with human placental ah receptor--a QSAR analysis.
Biochemical pharmacology 1990;40(4):737-41.
1990: Roberts E A; Johnson K C; Harper P A; Okey A B
Characterization of the Ah receptor mediating aryl hydrocarbon hydroxylase induction in the human liver cell line Hep G2.
Archives of biochemistry and biophysics 1990;276(2):442-50.
1989: Prokipcak R D; Faber L E; Okey A B
Characterization of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: use of chemical crosslinking and a monoclonal antibody directed against a 59-kDa protein associated with steroid receptors.
Archives of biochemistry and biophysics 1989;274(2):648-58.
1989: Denison M S; Vella L M; Okey A B
Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver: lack of sensitivity to alkaline phosphatase when compared with that of glucocorticoid receptor.
Archives of biochemistry and biophysics 1989;273(2):458-65.
1989: Roberts E A; Vella L M; Golas C L; Dafoe L A; Okey A B
Ah receptor in spleen of rodent and primate species: detection by binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Canadian journal of physiology and pharmacology 1989;67(6):594-600.
1989: Okey A B; Vella L M; Harper P A
Detection and characterization of a low affinity form of cytosolic Ah receptor in livers of mice nonresponsive to induction of cytochrome P1-450 by 3-methylcholanthrene.
Molecular pharmacology 1989;35(6):823-30.
1988: Prokipcak R D; Okey A B
Physicochemical characterization of the nuclear form of Ah receptor from mouse hepatoma cells exposed in culture to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Archives of biochemistry and biophysics 1988;267(2):811-28.
1988: Harper P A; Golas C L; Okey A B
Characterization of the Ah receptor and aryl hydrocarbon hydroxylase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and benz(a)anthracene in the human A431 squamous cell carcinoma line.
Cancer research 1988;48(9):2388-95.
1987: Manchester D K; Gordon S K; Golas C L; Roberts E A; Okey A B
Ah receptor in human placenta: stabilization by molybdate and characterization of binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo(a)pyrene.
Cancer research 1987;47(18):4861-8.
1987: Denison M S; Vella L M; Okey A B
Structure and function of the Ah receptor: sulfhydryl groups required for binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to cytosolic receptor from rodent livers.
Archives of biochemistry and biophysics 1987;252(2):388-95.
1986: Denison M S; Okey A B; Hamilton J W; Bloom S E; Wilkinson C F
Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: ontogeny in chick embryo liver.
Journal of biochemical toxicology 1986;1(3):39-49.
1986: Denison M S; Vella L M; Okey A B
Hepatic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Partial stabilization by molybdate.
The Journal of biological chemistry 1986;261(22):10189-95.
1986: Roberts E A; Golas C L; Okey A B
Ah receptor mediating induction of aryl hydrocarbon hydroxylase: detection in human lung by binding of 2,3,7,8-[3H]tetrachlorodibenzo-p-dioxin.
Cancer research 1986;46(7):3739-43.
1986: Okey A B; Roberts E A; Harper P A; Denison M S
Induction of drug-metabolizing enzymes: mechanisms and consequences.
Clinical biochemistry 1986;19(2):132-41.
1986: Denison M S; Harper P A; Okey A B
Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Codistribution of unoccupied receptor with cytosolic marker enzymes during fractionation of mouse liver, rat liver and cultured Hepa-1c1 cells.
European journal of biochemistry / FEBS 1986;155(2):223-9.
1986: Denison M S; Vella L M; Okey A B
Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols.
The Journal of biological chemistry 1986;261(9):3987-95.
1984: Okey A B; Vella L M; Iverson F
Ah receptor in primate liver: binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and carcinogenic aromatic hydrocarbons.
Canadian journal of physiology and pharmacology 1984;62(10):1292-5.
1984: Okey A B; Dubé A W; Vella L M
Binding of benzo(a)pyrene and dibenz(a,h)anthracene to the Ah receptor in mouse and rat hepatic cytosols.
Cancer research 1984;44(4):1426-32.
1984: Okey A B; Vella L M
Elevated binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene to the Ah receptor in hepatic cytosols from phenobarbital-treated rats and mice.
Biochemical pharmacology 1984;33(4):531-8.
1982: Okey A B; Vella L M
Binding of 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin to a common Ah receptor site in mouse and rat hepatic cytosols.
European journal of biochemistry / FEBS 1982;127(1):39-47.

Sign-in to see more