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Sam Okret

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Experimental Liver Neoplasms

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Co-Publications
Name
10
Pazirandeh, Ahmad
9
Jondal, Mikael
7
Rafter, Ingalill
5
Davani, Behrous
5
Lidén, Johan
4
Bladh, Lars-Göran
4
Fuxe, Kjell
4
Subramaniam, Nanthakumar
3
Samuelsson, Magnus
3
Poellinger, Lorenz
3
GUSTAFSSON, Jan-�ke
3
Wissink, S
3
Agnati, Luigi
3
Efendic, Suad
3
Cintra, A

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Publications

TOP 3
Qiao Shengjun; Okret Sam; Jondal Mikael
Thymocyte-synthesized glucocorticoids play a role in thymocyte homeostasis and are down-regulated by adrenocorticotropic hormone.
Bladh Lars-Göran; Johansson-Haque Krishan; Rafter Ingalill; Nilsson Stefan; Okret Sam
Inhibition of extracellular signal-regulated kinase (ERK) signaling participates in repression of nuclear factor (NF)-kappaB activity by glucocorticoids.
Johansson-Haque Krishan; Palanichamy Elanchelian; Okret Sam
Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP.

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All Publications

2009: Qiao Shengjun; Okret Sam; Jondal Mikael
Thymocyte-synthesized glucocorticoids play a role in thymocyte homeostasis and are down-regulated by adrenocorticotropic hormone.
Endocrinology 2009;150(9):4163-9.
2009: Bladh Lars-Göran; Johansson-Haque Krishan; Rafter Ingalill; Nilsson Stefan; Okret Sam
Inhibition of extracellular signal-regulated kinase (ERK) signaling participates in repression of nuclear factor (NF)-kappaB activity by glucocorticoids.
Biochimica et biophysica acta 2009;1793(3):439-46.
2008: Johansson-Haque Krishan; Palanichamy Elanchelian; Okret Sam
Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP.
Journal of molecular endocrinology 2008;41(4):239-49.
2008: Qiao Shengjun; Chen Liying; Okret Sam; Jondal Mikael
Age-related synthesis of glucocorticoids in thymocytes.
Experimental cell research 2008;314(16):3027-35.
2005: Johansson Anne-Sofie M; Lidén Johan; Okret Sam; Palmblad Jan E W
Effects of ethanol on cytokine generation and NFkappaB activity in human lung epithelial cell.
Biochemical pharmacology 2005;70(4):545-51.
2005: Pazirandeh Ahmad; Jondal Mikael; Okret Sam
Conditional expression of a glucocorticoid receptor transgene in thymocytes reveals a role for thymic-derived glucocorticoids in thymopoiesis in vivo.
Endocrinology 2005;146(6):2501-7.
2005: Bladh Lars-Göran; Lidén Johan; Dahlman-Wright Karin; Reimers Mark; Nilsson Stefan; Okret Sam
Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 repression.
Molecular pharmacology 2005;67(3):815-26.
2005: Bladh Lars-Göran; Lidén Johan; Pazirandeh Ahmad; Rafter Ingalill; Dahlman-Wright Karin; Nilsson Stefan; Okret Sam
Identification of target genes involved in the antiproliferative effect of glucocorticoids reveals a role for nuclear factor-(kappa)B repression.
Molecular endocrinology (Baltimore, Md.) 2005;19(3):632-43.
2004: Jondal Mikael; Pazirandeh Ahmad; Okret Sam
Different roles for glucocorticoids in thymocyte homeostasis?
Trends in immunology 2004;25(11):595-600.
2004: Pazirandeh Ahmad; Jondal Mikael; Okret Sam
Glucocorticoids delay age-associated thymic involution through directly affecting the thymocytes.
Endocrinology 2004;145(5):2392-401.
2004: Davani Behrous; Portwood Neil; Bryzgalova Galina; Reimer Martina Kvist; Heiden Thomas; Ostenson Claes-Göran; Okret Sam; Ahren Bo; Efendic Suad; Khan Akhtar
Aged transgenic mice with increased glucocorticoid sensitivity in pancreatic beta-cells develop diabetes.
Diabetes 2004;53 Suppl 1():S51-9.
2003: Joseph Bertrand; Wallén-Mackenzie Asa; Benoit Gérard; Murata Takashi; Joodmardi Eliza; Okret Sam; Perlmann Thomas
p57(Kip2) cooperates with Nurr1 in developing dopamine cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15619-24.
2003: Lidén Johan; Ek Alexandra; Palmberg Lena; Okret Sam; Larsson Kjell
Organic dust activates NF-kappaB in lung epithelial cells.
Respiratory medicine 2003;97(8):882-92.
2003: Alheim K; Corness J; Samuelsson M K R; Bladh L-G; Murata T; Nilsson T; Okret S
Identification of a functional glucocorticoid response element in the promoter of the cyclin-dependent kinase inhibitor p57Kip2.
Journal of molecular endocrinology 2003;30(3):359-68.
2003: Subramaniam Nanthakumar; Campión Javier; Rafter Ingalill; Okret Sam
Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1.
The Biochemical journal 2003;370(Pt 3):1087-95.
2002: Samuelsson Magnus K R; Pazirandeh Ahmad; Okret Sam
A pro-apoptotic effect of the CDK inhibitor p57(Kip2) on staurosporine-induced apoptosis in HeLa cells.
Biochemical and biophysical research communications 2002;296(3):702-9.
2002: Pazirandeh Ahmad; Xue Yintong; Prestegaard Tore; Jondal Mikael; Okret Sam
Effects of altered glucocorticoid sensitivity in the T cell lineage on thymocyte and T cell homeostasis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):727-9.
2001: Doppler W; Windegger M; Soratroi C; Tomasi J; Lechner J; Rusconi S; Cato A C; Almlöf T; Liden J; Okret S; Gustafsson J A; Richard-Foy H; Starr D B; Klocker H; Edwards D; Geymayer S
Expression level-dependent contribution of glucocorticoid receptor domains for functional interaction with STAT5.
Molecular and cellular biology 2001;21(9):3266-79.
2001: Jondal M; Pazirandeh A; Okret S
A role for glucocorticoids in the thymus?
Trends in immunology 2001;22(4):185-6.
2000: Davani B; Khan A; Hult M; Mårtensson E; Okret S; Efendic S; Jörnvall H; Oppermann U C
Type 1 11beta -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets.
The Journal of biological chemistry 2000;275(45):34841-4.
2000: Pazirandeh A; Xue Y; Okret S; Jondal M
Glucocorticoid resistance in thymocytes from mice expressing a T cell receptor transgene.
Biochemical and biophysical research communications 2000;276(1):189-96.
2000: Liden J; Rafter I; Truss M; Gustafsson J A; Okret S
Glucocorticoid effects on NF-kappaB binding in the transcription of the ICAM-1 gene.
Biochemical and biophysical research communications 2000;273(3):1008-14.
1999: Samuelsson M K; Pazirandeh A; Davani B; Okret S
p57Kip2, a glucocorticoid-induced inhibitor of cell cycle progression in HeLa cells.
Molecular endocrinology (Baltimore, Md.) 1999;13(11):1811-22.
1999: Subramaniam N; Treuter E; Okret S
Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoids.
The Journal of biological chemistry 1999;274(25):18121-7.
1999: Pazirandeh A; Xue Y; Rafter I; Sjövall J; Jondal M; Okret S
Paracrine glucocorticoid activity produced by mouse thymic epithelial cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):893-901.
1998: Subramaniam N; Cairns W; Okret S
Glucocorticoids repress transcription from a negative glucocorticoid response element recognized by two homeodomain-containing proteins, Pbx and Oct-1.
The Journal of biological chemistry 1998;273(36):23567-74.
1998: Dumont A; Hehner S P; Schmitz M L; Gustafsson J A; Lidén J; Okret S; van der Saag P T; Wissink S; van der Burg B; Herrlich P; Haegeman G; De Bosscher K; Fiers W
Cross-talk between steroids and NF-kappa B: what language?
Trends in biochemical sciences 1998;23(7):233-5.
1998: Ling Z C; Khan A; Delauny F; Davani B; Ostenson C G; Gustafsson J A; Okret S; Landau B R; Efendic S
Increased glucocorticoid sensitivity in islet beta-cells: effects on glucose 6-phosphatase, glucose cycling and insulin release.
Diabetologia 1998;41(6):634-9.
1997: Delaunay F; Khan A; Cintra A; Davani B; Ling Z C; Andersson A; Ostenson C G; Gustafsson J; Efendic S; Okret S
Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids.
The Journal of clinical investigation 1997;100(8):2094-8.
1997: Liden J; Delaunay F; Rafter I; Gustafsson J; Okret S
A new function for the C-terminal zinc finger of the glucocorticoid receptor. Repression of RelA transactivation.
The Journal of biological chemistry 1997;272(34):21467-72.
1997: van der Burg B; Liden J; Okret S; Delaunay F; Wissink S; van der Saag P T; Gustafsson J A
Nuclear Factor-kappa B Repression in Antiinflammation and Immunosuppression by Glucocorticoids.
Trends in endocrinology and metabolism: TEM 1997;8(4):152-7.
1997: Subramaniam N; Cairns W; Okret S
Studies on the mechanism of glucocorticoid-mediated repression from a negative glucocorticoid response element from the bovine prolactin gene.
DNA and cell biology 1997;16(2):153-63.
1996: Delaunay F; Liden J; Gustafsson J A; Okret S
Glucocorticoid receptor lacking the tau 1 transactivation domain is a gene-specific regulator of the wild-type glucocorticoid-receptor activity.
European journal of biochemistry / FEBS 1996;242(3):839-45.
1996: Matheson H; Branting C; Rafter I; Okret S; Rafter J
Increased c-fos mRNA and binding to the AP-1 recognition sequence accompanies the proliferative response to deoxycholate of HT29 cells.
Carcinogenesis 1996;17(3):421-6.
1995: Caldenhoven E; Liden J; Wissink S; Van de Stolpe A; Raaijmakers J; Koenderman L; Okret S; Gustafsson J A; Van der Saag P T
Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.
Molecular endocrinology (Baltimore, Md.) 1995;9(4):401-12.
1993: Gearing K L; Cairns W; Okret S; Gustafsson J A
Heterogeneity in the 5' untranslated region of the rat glucocorticoid receptor mRNA.
The Journal of steroid biochemistry and molecular biology 1993;46(5):635-9.
1993: Cairns C; Cairns W; Okret S
Inhibition of gene expression by steroid hormone receptors via a negative glucocorticoid response element: evidence for the involvement of DNA-binding and agonistic effects of the antiglucocorticoid/antiprogestin RU486.
DNA and cell biology 1993;12(8):695-702.
1993: Cintra A; Solfrini V; Bunnemann B; Okret S; Bortolotti F; Gustafsson J A; Fuxe K
Prenatal development of glucocorticoid receptor gene expression and immunoreactivity in the rat brain and pituitary gland: a combined in situ hybridization and immunocytochemical analysis.
Neuroendocrinology 1993;57(6):1133-47.
1993: Gearing K L; Gustafsson J A; Okret S
Heterogeneity in the polyglutamine tract of the glucocorticoid receptor from different rat strains.
Nucleic acids research 1993;21(8):2014.
1991: Cairns W; Cairns C; Pongratz I; Poellinger L; Okret S
Assembly of a glucocorticoid receptor complex prior to DNA binding enhances its specific interaction with a glucocorticoid response element.
The Journal of biological chemistry 1991;266(17):11221-6.
1991: Tanaka H; Dong Y; Li Q; Okret S; Gustafsson J A
Identification and characterization of a cis-acting element that interferes with glucocorticoid-inducible activation of the mouse mammary tumor virus promoter.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5393-7.
1991: Okret S; Dong Y; Brönnegård M; Gustafsson J A
Regulation of glucocorticoid receptor expression.
Biochimie 1991;73(1):51-9.
1991: Cintra A; Fuxe K; Solfrini V; Agnati L F; Tinner B; Wikström A C; Staines W; Okret S; Gustafsson J A
Central peptidergic neurons as targets for glucocorticoid action. Evidence for the presence of glucocorticoid receptor immunoreactivity in various types of classes of peptidergic neurons.
The Journal of steroid biochemistry and molecular biology 1991;40(1-3):93-103.
1991: Okret S; Dong Y; Tanaka H; Cairns B; Gustafsson J A
The mechanism for glucocorticoid-resistance in a rat hepatoma cell variant that contains functional glucocorticoid receptor.
The Journal of steroid biochemistry and molecular biology 1991;40(1-3):353-61.
1990: Dong Y; Cairns W; Okret S; Gustafsson J A
A glucocorticoid-resistant rat hepatoma cell variant contains functional glucocorticoid receptor.
The Journal of biological chemistry 1990;265(13):7526-31.
1989: Ceccatelli S; Dagerlind A; Schalling M; Wikstróm A C; Okret S; Gustafsson J A; Goldstein M; Hökfelt T
The glucocorticoid receptor in the adrenal gland is localized in the cytoplasm of adrenaline cells.
Acta physiologica Scandinavica 1989;137(4):559-60.
1989: Dong Y; Aronsson M; Gustafsson J A; Okret S
The mechanism of cAMP-induced glucocorticoid receptor expression. Correlation to cellular glucocorticoid response.
The Journal of biological chemistry 1989;264(23):13679-83.
1989: Härfstrand A; Cintra A; Fuxe K; Aronsson M; Wikström A C; Okret S; Gustafsson J A; Agnati L F
Regional differences in glucocorticoid receptor immunoreactivity among neuropeptide Y immunoreactive neurons of the rat brain.
Acta physiologica Scandinavica 1989;135(1):3-9.
1988: Dong Y; Poellinger L; Gustafsson J A; Okret S
Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms.
Molecular endocrinology (Baltimore, Md.) 1988;2(12):1256-64.
1988: Aronsson M; Fuxe K; Dong Y; Agnati L F; Okret S; Gustafsson J A
Localization of glucocorticoid receptor mRNA in the male rat brain by in situ hybridization.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):9331-5.
1988: Dong Y; Poellinger L; Okret S; Höög J O; von Bahr-Lindström H; Jörnvall H; Gustafsson J A
Regulation of gene expression of class I alcohol dehydrogenase by glucocorticoids.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(3):767-71.

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