Ko Okumura

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Kamijo Seiji; Takai Toshiro; Kuhara Takatoshi; Tokura Tomoko; Ushio Hiroko; Ota Mikiko; Harada Norihiro; Ogawa Hideoki; Okumura Ko
Cupressaceae pollen grains modulate dendritic cell response and exhibit IgE-inducing adjuvant activity in vivo.
Ishikawa Yasuko; Tokura Tomoko; Ushio Hiroko; Niyonsaba François; Yamamoto Yuji; Tadokoro Tadahiro; Ogawa Hideoki; Okumura Ko
Lipid-soluble components of honeybee-collected pollen exert antiallergic effect by inhibiting IgE-mediated mast cell activation in vivo.
Fukai Tatsuo; Nishiyama Chiharu; Kanada Shunsuke; Nakano Nobuhiro; Hara Mutsuko; Tokura Tomoko; Ikeda Shigaku; Ogawa Hideoki; Okumura Ko
Involvement of PU.1 in the transcriptional regulation of TNF-alpha.

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2009: Kamijo Seiji; Takai Toshiro; Kuhara Takatoshi; Tokura Tomoko; Ushio Hiroko; Ota Mikiko; Harada Norihiro; Ogawa Hideoki; Okumura Ko
Cupressaceae pollen grains modulate dendritic cell response and exhibit IgE-inducing adjuvant activity in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(10):6087-94.
2009: Ishikawa Yasuko; Tokura Tomoko; Ushio Hiroko; Niyonsaba François; Yamamoto Yuji; Tadokoro Tadahiro; Ogawa Hideoki; Okumura Ko
Lipid-soluble components of honeybee-collected pollen exert antiallergic effect by inhibiting IgE-mediated mast cell activation in vivo.
Phytotherapy research : PTR 2009;23(11):1581-6.
2009: Fukai Tatsuo; Nishiyama Chiharu; Kanada Shunsuke; Nakano Nobuhiro; Hara Mutsuko; Tokura Tomoko; Ikeda Shigaku; Ogawa Hideoki; Okumura Ko
Involvement of PU.1 in the transcriptional regulation of TNF-alpha.
Biochemical and biophysical research communications 2009;388(1):102-6.
2009: Potaczek Daniel P; Maeda Keiko; Wang Qing-Hui; Nakano Nobuhiro; Kanada Shunsuke; Stepien Ewa; Branicka Agnieszka; Fukai Tatsuo; Hara Mutsuko; Tokura Tomoko; Ogawa Hideoki; Undas Anetta; Okumura Ko; Nishiyama Chiharu
FcepsilonRIalpha gene -18483A>C polymorphism affects transcriptional activity through YY1 binding.
Immunogenetics 2009;61(9):649-55.
2009: Potaczek D P; Okumura K; Nishiyama C
FCER1A genetic variability and serum IgE levels.
Allergy 2009;64(9):1383.
2009: Wang Xiao-Ling; Takai Toshiro; Kamijo Seiji; Gunawan Hendra; Ogawa Hideoki; Okumura Ko
NADPH oxidase activity in allergenic pollen grains of different plant species.
Biochemical and biophysical research communications 2009;387(3):430-4.
2009: Kato T; Takai T; Fujimura T; Matsuoka H; Ogawa T; Murayama K; Ishii A; Ikeda S; Okumura K; Ogawa H
Mite serine protease activates protease-activated receptor-2 and induces cytokine release in human keratinocytes.
Allergy 2009;64(9):1366-74.
2009: Le T A; Takai T; Kinoshita H; Suto H; Ikeda S; Okumura K; Ogawa H
Inhibition of double-stranded RNA-induced TSLP in human keratinocytes by glucocorticoids.
Allergy 2009;64(8):1231-2.
2009: Ito Tomonobu; Nishiyama Chiharu; Nakano Nobuhiro; Nishiyama Makoto; Usui Yoshihiko; Takeda Kazuyoshi; Kanada Shunsuke; Fukuyama Kanako; Akiba Hisaya; Tokura Tomoko; Hara Mutsuko; Tsuboi Ryoji; Ogawa Hideoki; Okumura Ko
Roles of PU.1 in monocyte- and mast cell-specific gene regulation: PU.1 transactivates CIITA pIV in cooperation with IFN-gamma.
International immunology 2009;21(7):803-16.
2009: Takai Toshiro; Ochiai Yuri; Ichikawa Saori; Sato Emi; Ogawa Takasuke; Tokura Tomoko; Kuhara Takatoshi; Kawai Hiroshi; Hatanaka Hideki; Takahashi Seizo; Ogawa Hideoki; Okumura Ko
Enzyme-linked immunosorbent assays with high sensitivity for antigen-specific and total murine IgE: a useful tool for the study of allergies in mouse models.
Allergology international : official journal of the Japanese Society of Allergology 2009;58(2):225-35.
2009: Totsuka Teruji; Kanai Takanori; Nemoto Yasuhiro; Tomita Takayuki; Okamoto Ryuichi; Tsuchiya Kiichiro; Nakamura Tetsuya; Sakamoto Naoya; Akiba Hisaya; Okumura Ko; Yagita Hideo; Watanabe Mamoru
RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6079-87.
2009: Usui Yoshihiko; Takeuchi Masaru; Hattori Takaaki; Okunuki Yoko; Nagasawa Kazumi; Kezuka Takeshi; Okumura Ko; Yagita Hideo; Akiba Hisaya; Goto Hiroshi
Suppression of experimental autoimmune uveoretinitis by regulatory dendritic cells in mice.
Archives of ophthalmology 2009;127(4):514-9.
2009: Nakayama Masafumi; Akiba Hisaya; Takeda Kazuyoshi; Kojima Yuko; Hashiguchi Masaaki; Azuma Miyuki; Yagita Hideo; Okumura Ko
Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.
Blood 2009;113(16):3821-30.
2009: Sekine Chiyoko; Moriyama Yuko; Koyanagi Akemi; Koyama Noriko; Ogata Hideko; Okumura Ko; Yagita Hideo
Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands.
International immunology 2009;21(3):295-301.
2009: Shimokawa N; Nishiyama C; Hirota T; Tamari M; Hara M; Ikeda S; Okumura K; Ogawa H
Functional analysis of a polymorphism in the promoter region of the IL-12/23p40 gene.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(2):228-35.
2009: Seto Takahiko; Takai Toshiro; Ebihara Nobuyuki; Matsuoka Hiroyuki; Wang Xiao-Ling; Ishii Akira; Ogawa Hideoki; Murakami Akira; Okumura Ko
SLPI prevents cytokine release in mite protease-exposed conjunctival epithelial cells.
Biochemical and biophysical research communications 2009;379(3):681-5.
2009: Niyonsaba F; Suzuki A; Ushio H; Nagaoka I; Ogawa H; Okumura K
The human antimicrobial peptide dermcidin activates normal human keratinocytes.
The British journal of dermatology 2009;160(2):243-9.
2009: Nakano Nobuhiro; Nishiyama Chiharu; Yagita Hideo; Koyanagi Akemi; Akiba Hisaya; Chiba Shigeru; Ogawa Hideoki; Okumura Ko
Notch signaling confers antigen-presenting cell functions on mast cells.
The Journal of allergy and clinical immunology 2009;123(1):74-81.e1.
2009: Kinoshita Hirokazu; Takai Toshiro; Le Tuan Anh; Kamijo Seiji; Wang Xiao Ling; Ushio Hiroko; Hara Mutsuko; Kawasaki Junko; Vu Anh Tuan; Ogawa Takasuke; Gunawan Hendra; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
The Journal of allergy and clinical immunology 2009;123(1):179-86.
2009: Niyonsaba François; Nagaoka Isao; Ogawa Hideoki; Okumura Ko
Multifunctional antimicrobial proteins and peptides: natural activators of immune systems.
Current pharmaceutical design 2009;15(21):2393-413.
2009: Potaczek Daniel P; Nishiyama Chiharu; Sanak Marek; Szczeklik Andrew; Okumura Ko
Genetic variability of the high-affinity IgE receptor alpha-subunit (FcepsilonRIalpha).
Immunologic research 2009;45(1):75-84.
2008: Niwa Yusuke; Nishiyama Chiharu; Nakano Nobuhiro; Kamei Asuka; Kato Hisanori; Kanada Shunsuke; Ikeda Shigaku; Ogawa Hideoki; Okumura Ko
Opposite effects of PU.1 on mast cell stimulation.
Biochemical and biophysical research communications 2008;375(1):95-100.
2008: Wang Qing-Hui; Nishiyama Chiharu; Nakano Nobuhiro; Shimokawa Naomi; Hara Mutsuko; Kanada Shunsuke; Ogawa Hideoki; Okumura Ko
Suppressive effect of Elf-1 on FcepsilonRI alpha-chain expression in primary mast cells.
Immunogenetics 2008;60(10):557-63.
2008: Ebihara Nobuyuki; Funaki Toshinari; Matsuda Hiroshi; Okumura Ko; Murakami Akira; Ra Chisei
Corneal abnormalities in the NC/Nga mouse: an atopic dermatitis model.
Cornea 2008;27(8):923-9.
2008: Sawada Taisuke; Nishiyama Chiharu; Kishi Takuma; Sasazuki Tomonari; Komazawa-Sakon Sachiko; Xue Xin; Piao Jiang-Hu; Ogata Hideko; Nakayama Jun-ichi; Taki Tomohiko; Hayashi Yasuhide; Watanabe Mamoru; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity.
The Journal of biological chemistry 2008;283(39):26820-8.
2008: Takeda Kazuyoshi; Kojima Yuko; Ikejima Kenichi; Harada Kenichi; Yamashina Shunhei; Okumura Kyoko; Aoyama Tomonori; Frese Steffen; Ikeda Hiroko; Haynes Nicole M; Cretney Erika; Yagita Hideo; Sueyoshi Noriyoshi; Sato Nobuhiro; Nakanuma Yasuni; Smyth Mark J; Okumura Ko
Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10895-900.
2008: Nakajima Akihito; Kurihara Hidetake; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
Mitochondrial Extrusion through the cytoplasmic vacuoles during cell death.
The Journal of biological chemistry 2008;283(35):24128-35.
2008: Zheng Yan; Niyonsaba François; Ushio Hiroko; Ikeda Shigaku; Nagaoka Isao; Okumura Ko; Ogawa Hideoki
Microbicidal protein psoriasin is a multifunctional modulator of neutrophil activation.
Immunology 2008;124(3):357-67.
2008: Moriyama Yuko; Sekine Chiyoko; Koyanagi Akemi; Koyama Noriko; Ogata Hideko; Chiba Shigeru; Hirose Sachiko; Okumura Ko; Yagita Hideo
Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice.
International immunology 2008;20(6):763-73.
2008: Potaczek D P; Nishiyama C; Sanak M; Szczeklik A; Okumura K; Ogawa H
FCER1A gene exon 1A polymorphisms in Japanese and Polish subjects--a comparative analysis of haplotypes.
Allergy 2008;63(5):626-7.
2008: Ishikawa Yasuko; Tokura Tomoko; Nakano Nobuhiro; Hara Mutsuko; Niyonsaba François; Ushio Hiroko; Yamamoto Yuji; Tadokoro Tadahiro; Okumura Ko; Ogawa Hideoki
Inhibitory effect of honeybee-collected pollen on mast cell degranulation in vivo and in vitro.
Journal of medicinal food 2008;11(1):14-20.
2008: Gunawan Hendra; Takai Toshiro; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Protease activity of allergenic pollen of cedar, cypress, juniper, birch and ragweed.
Allergology international : official journal of the Japanese Society of Allergology 2008;57(1):83-91.
2008: Nagasawa Masayuki; Yi Zhu; Imashuku Shinsaku; Nonoyama Shigeaki; Ogawa Kazuyuki; Okumura Ko; Mizutani Shuki
Soluble TWEAK is markedly elevated in hemophagocytic lymphohistiocytosis.
American journal of hematology 2008;83(3):222-5.
2008: Wong Muh Geot; Suzuki Yusuke; Tanifuji Chiaki; Akiba Hisaya; Okumura Ko; Sugaya Takeshi; Yamamoto Tokunori; Horikoshi Satoshi; Tan Si Yen; Pollock Carol; Tomino Yasuhiko
Peritubular ischemia contributes more to tubular damage than proteinuria in immune-mediated glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2008;19(2):290-7.
2008: Ng William; Nishiyama Chiharu; Mizoguchi Masayuki; Nakano Nobuhiro; Suga Yasushi; Ikeda Shigaku; Itoh Shigeru; Kinoshita Katsuyuki; Okumura Ko; Ogawa Hideoki
Human umbilical cord epithelial cells express Notch1: implications for its epidermal-like differentiation.
Journal of dermatological science 2008;49(2):143-52.
2008: Jayawardana Sumanasiri T M; Ushio Hiroko; Niyonsaba François; Gondokaryono Srie Prihianti; Takenaka Hiroshi; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Monomeric IgE and lipopolysaccharide synergistically prevent mast-cell apoptosis.
Biochemical and biophysical research communications 2008;365(1):137-42.
2008: Ito Y; Kanai T; Totsuka T; Okamoto R; Tsuchiya K; Nemoto Y; Yoshioka A; Tomita T; Nagaishi T; Sakamoto N; Sakanishi T; Okumura K; Yagita H; Watanabe M
Blockade of NKG2D signaling prevents the development of murine CD4+ T cell-mediated colitis.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(1):G199-207.
2008: Nakajima A; Kojima Y; Nakayama M; Yagita H; Okumura K; Nakano H
Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells.
Oncogene 2008;27(1):76-84.
2008: Takagi Atsushi; Nishiyama Chiharu; Maeda Keiko; Tokura Tomoko; Kawada Hiroshi; Kanada Shunsuke; Niwa Yusuke; Nakano Nobuhiro; Mayuzumi Nobuyasu; Nishiyama Makoto; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Role of Sp1 in transcription of human ATP2A2 gene in keratinocytes.
The Journal of investigative dermatology 2008;128(1):96-103.
2008: Gunawan Hendra; Takai Toshiro; Kamijo Seiji; Wang Xiao Ling; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Characterization of proteases, proteins, and eicosanoid-like substances in soluble extracts from allergenic pollen grains.
International archives of allergy and immunology 2008;147(4):276-88.
2008: Nakano Nobuhiro; Nishiyama Chiharu; Tokura Tomoko; Nagasako-Akazome Yoko; Ohtake Yasuyuki; Okumura Ko; Ogawa Hideoki
Procyanidin C1 from apple extracts inhibits Fc epsilon RI-mediated mast cell activation.
International archives of allergy and immunology 2008;147(3):213-21.
2008: Ogawa Takasuke; Takai Toshiro; Kato Takeshi; Kikuchi Yuko; Niyonsaba François; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Upregulation of the release of granulocyte-macrophage colony-stimulating factor from keratinocytes stimulated with cysteine protease activity of recombinant major mite allergens, Der f 1 and Der p 1.
International archives of allergy and immunology 2008;146(1):27-35.
2007: Heissig Beate; Lund Leif R; Akiyama Haruyo; Ohki Makiko; Morita Yohei; Rømer John; Nakauchi Hiromitsu; Okumura Ko; Ogawa Hideoki; Werb Zena; Danø Keld; Hattori Koichi
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
Cell stem cell 2007;1(6):658-70.
2007: Hattori Takaaki; Usui Yoshihiko; Okunuki Yoko; Sonoda Yasushi; Usui Masahiko; Takada Eiko; Mizuguchi Junichiro; Yagita Hideo; Okumura Ko; Akiba Hisaya; Takeuchi Masaru
Blockade of the OX40 ligand prolongs corneal allograft survival.
European journal of immunology 2007;37(12):3597-604.
2007: Zheng Y; Niyonsaba F; Ushio H; Nagaoka I; Ikeda S; Okumura K; Ogawa H
Cathelicidin LL-37 induces the generation of reactive oxygen species and release of human alpha-defensins from neutrophils.
The British journal of dermatology 2007;157(6):1124-31.
2007: Gondokaryono Srie Prihianti; Ushio Hiroko; Niyonsaba François; Hara Mutsuko; Takenaka Hiroshi; Jayawardana Sumanasiri T M; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
The extra domain A of fibronectin stimulates murine mast cells via toll-like receptor 4.
Journal of leukocyte biology 2007;82(3):657-65.
2007: Takeda Kazuyoshi; Okumura Ko; Smyth Mark J
Combination antibody-based cancer immunotherapy.
Cancer science 2007;98(9):1297-302.
2007: Seko Yoshinori; Yagita Hideo; Okumura Ko; Azuma Miyuki; Nagai Ryozo
Roles of programmed death-1 (PD-1)/PD-1 ligands pathway in the development of murine acute myocarditis caused by coxsackievirus B3.
Cardiovascular research 2007;75(1):158-67.
2007: Yuminamochi Eri; Koike Taisuke; Takeda Kazuyoshi; Horiuchi Isao; Okumura Ko
Interleukin-12- and interferon-gamma-mediated natural killer cell activation by Agaricus blazei Murill.
Immunology 2007;121(2):197-206.
2007: Nakano Nobuhiro; Nishiyama Chiharu; Kanada Shunsuke; Niwa Yusuke; Shimokawa Naomi; Ushio Hiroko; Nishiyama Makoto; Okumura Ko; Ogawa Hideoki
Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections.
Blood 2007;109(11):4846-55.
2007: Takeda K; Stagg J; Yagita H; Okumura K; Smyth M J
Targeting death-inducing receptors in cancer therapy.
Oncogene 2007;26(25):3745-57.
2007: Takeda Kazuyoshi; Okumura Ko
Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human NK-cell activity.
The Journal of nutrition 2007;137(3 Suppl 2):791S-3S.
2007: Tsuchihashi Hitoshi; Hasegawa Toshio; Sumiyoshi Koji; Ogawa Hideoki; Ikeda Shigaku; Ando Takashi; Nakao Atsuhito; Okumura Ko
TWEAK inhibits TGF-beta-induced contraction of normal and keloid fibroblast-embedded collagen gel.
Journal of dermatological science 2007;45(3):216-8.
2007: Niyonsaba François; Ushio Hiroko; Nakano Nobuhiro; Ng William; Sayama Koji; Hashimoto Koji; Nagaoka Isao; Okumura Ko; Ogawa Hideoki
Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines.
The Journal of investigative dermatology 2007;127(3):594-604.
2007: Piao Jiang-Hu; Yoshida Hisahiro; Yeh Wen-Chen; Doi Takahiro; Xue Xin; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
TNF receptor-associated factor 2-dependent canonical pathway is crucial for the development of Peyer's patches.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2272-7.
2007: Chen Xuejun; Niyonsaba François; Ushio Hiroko; Hara Mutsuko; Yokoi Hidenori; Matsumoto Kenji; Saito Hirohisa; Nagaoka Isao; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Antimicrobial peptides human beta-defensin (hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability.
European journal of immunology 2007;37(2):434-44.
2006: Nakajima Akihito; Komazawa-Sakon Sachiko; Takekawa Mutsuhiro; Sasazuki Tomonari; Yeh Wen-Chen; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway.
The EMBO journal 2006;25(23):5549-59.
2006: Kamata Koichi; Kamijo Seiji; Nakajima Atsuo; Koyanagi Akemi; Kurosawa Hisashi; Yagita Hideo; Okumura Ko
Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6433-9.
2006: Usui Yoshihiko; Akiba Hisaya; Takeuchi Masaru; Kezuka Takeshi; Takeuchi Aya; Hattori Takaaki; Okunuki Yoko; Yamazaki Tomohide; Yagita Hideo; Usui Masahiko; Okumura Ko
The role of the ICOS/B7RP-1 T cell costimulatory pathway in murine experimental autoimmune uveoretinitis.
European journal of immunology 2006;36(11):3071-81.
2006: Oikawa Tsunekazu; Kamimura Yosuke; Akiba Hisaya; Yagita Hideo; Okumura Ko; Takahashi Hiroki; Zeniya Mikio; Tajiri Hisao; Azuma Miyuki
Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4281-7.
2006: Takeda K; Suzuki T; Shimada S-I; Shida K; Nanno M; Okumura K
Interleukin-12 is involved in the enhancement of human natural killer cell activity by Lactobacillus casei Shirota.
Clinical and experimental immunology 2006;146(1):109-15.
2006: Kikuchi Yuko; Takai Toshiro; Kuhara Takatoshi; Ota Mikiko; Kato Takeshi; Hatanaka Hideki; Ichikawa Saori; Tokura Tomoko; Akiba Hisaya; Mitsuishi Kouichi; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Crucial commitment of proteolytic activity of a purified recombinant major house dust mite allergen Der p1 to sensitization toward IgE and IgG responses.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1609-17.
2006: Takagi Atsushi; Nishiyama Chiharu; Kanada Shunsuke; Niwa Yusuke; Fukuyama Kanako; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Prolonged MHC class II expression and CIITA transcription in human keratinocytes.
Biochemical and biophysical research communications 2006;347(2):388-93.
2006: Kamijo Seiji; Nakajima Atsuo; Ikeda Kaori; Aoki Kazuhiro; Ohya Keiichi; Akiba Hisaya; Yagita Hideo; Okumura Ko
Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody.
Biochemical and biophysical research communications 2006;347(1):124-32.
2006: Kanai Takanori; Uraushihara Koji; Totsuka Teruji; Nemoto Yasuhiro; Fujii Rei; Kawamura Takahiro; Makita Shin; Sawada Daisuke; Yagita Hideo; Okumura Ko; Watanabe Mamoru
Ameliorating effect of saporin-conjugated anti-CD11b monoclonal antibody in a murine T-cell-mediated chronic colitis.
Journal of gastroenterology and hepatology 2006;21(7):1136-42.
2006: Maeda Keiko; Nishiyama Chiharu; Tokura Tomoko; Nakano Hiroyasu; Kanada Shunsuke; Nishiyama Makoto; Okumura Ko; Ogawa Hideoki
FOG-1 represses GATA-1-dependent FcepsilonRI beta-chain transcription: transcriptional mechanism of mast-cell-specific gene expression in mice.
Blood 2006;108(1):262-9.
2006: Uno Tomoyasu; Takeda Kazuyoshi; Kojima Yuko; Yoshizawa Hirohisa; Akiba Hisaya; Mittler Robert S; Gejyo Fumitake; Okumura Ko; Yagita Hideo; Smyth Mark J
Eradication of established tumors in mice by a combination antibody-based therapy.
Nature medicine 2006;12(6):693-8.
2006: Nakano H; Nakajima A; Sakon-Komazawa S; Piao J-H; Xue X; Okumura K
Reactive oxygen species mediate crosstalk between NF-kappaB and JNK.
Cell death and differentiation 2006;13(5):730-7.
2006: Kikuchi Yuko; Takai Toshiro; Ota Mikiko; Kato Takeshi; Takeda Ken; Mitsuishi Kouichi; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Application of immunoreaction enhancer solutions to an enzyme-linked immunosorbent assay for antigen-specific IgE in mice immunized with recombinant major mite allergens or ovalbumin.
International archives of allergy and immunology 2006;141(4):322-30.
2006: Takai Toshiro; Mizuuchi Eri; Kikuchi Yuko; Nagamune Teruyuki; Okumura Ko; Ogawa Hideoki
Glycosylation of recombinant proforms of major house dust mite allergens Der p 1 and Der f 1 decelerates the speed of maturation.
International archives of allergy and immunology 2006;139(3):181-7.
2005: Nakano Nobuhiro; Nakao Atsuhito; Uchida Takafumi; Shirasaka Norifumi; Yoshizumi Hajime; Okumura Ko; Tsuboi Ryoji; Ogawa Hideoki
Effects of arachidonic acid analogs on FcepsilonRI-mediated activation of mast cells.
Biochimica et biophysica acta 2005;1738(1-3):19-28.
2005: Takaya Norihide; Katoh Youichi; Iwabuchi Kazuhisa; Hayashi Ichiro; Konishi Hakuoh; Itoh Seigo; Okumura Ko; Ra Chisei; Nagaoka Isao; Daida Hiroyuki
Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor gamma-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury.
Journal of molecular and cellular cardiology 2005;39(6):856-64.
2005: Miyahira Yasushi; Takashima Yasuhiro; Kobayashi Seiki; Matsumoto Yasunobu; Takeuchi Tsutomu; Ohyanagi-Hara Mutsuko; Yoshida Ayako; Ohwada Akihiko; Akiba Hisaya; Yagita Hideo; Okumura Ko; Ogawa Hideoki
Immune responses against a single CD8+-T-cell epitope induced by virus vector vaccination can successfully control Trypanosoma cruzi infection.
Infection and immunity 2005;73(11):7356-65.
2005: Chen Xuejun; Niyonsaba François; Ushio Hiroko; Okuda Daiju; Nagaoka Isao; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli.
Journal of dermatological science 2005;40(2):123-32.
2005: Tokura Tomoko; Nakano Nobuhiro; Ito Tomonobu; Matsuda Hironori; Nagasako-Akazome Yoko; Kanda Tomomasa; Ikeda Mitsuo; Okumura Ko; Ogawa Hideoki; Nishiyama Chiharu
Inhibitory effect of polyphenol-enriched apple extracts on mast cell degranulation in vitro targeting the binding between IgE and FcepsilonRI.
Bioscience, biotechnology, and biochemistry 2005;69(10):1974-7.
2005: Xue Xin; Piao Jiang-Hu; Nakajima Akihito; Sakon-Komazawa Sachiko; Kojima Yuko; Mori Kazutoshi; Yagita Hideo; Okumura Ko; Harding Heather; Nakano Hiroyasu
Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha.
The Journal of biological chemistry 2005;280(40):33917-25.
2005: Heissig Beate; Rafii Shahin; Akiyama Haruyo; Ohki Yuichi; Sato Yayoi; Rafael Tejada; Zhu Zhenping; Hicklin Daniel J; Okumura Ko; Ogawa Hideoki; Werb Zena; Hattori Koichi
Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization.
The Journal of experimental medicine 2005;202(6):739-50.
2005: Akiba Hisaya; Takeda Kazuyoshi; Kojima Yuko; Usui Yoshihiko; Harada Norihiro; Yamazaki Tomohide; Ma Juan; Tezuka Katsunari; Yagita Hideo; Okumura Ko
The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2340-8.
2005: Niyonsaba François; Ushio Hiroko; Nagaoka Isao; Okumura Ko; Ogawa Hideoki
The human beta-defensins (-1, -2, -3, -4) and cathelicidin LL-37 induce IL-18 secretion through p38 and ERK MAPK activation in primary human keratinocytes.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1776-84.
2005: Yamazaki Tomohide; Akiba Hisaya; Koyanagi Akemi; Azuma Miyuki; Yagita Hideo; Okumura Ko
Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1586-92.
2005: Nakano N; Nakao A; Ishidoh K; Tsuboi R; Kominami E; Okumura K; Ogawa H
CDK5 regulates cell-cell and cell-matrix adhesion in human keratinocytes.
The British journal of dermatology 2005;153(1):37-45.
2005: Kato Takeshi; Takai Toshiro; Mitsuishi Kouichi; Okumura Ko; Ogawa Hideoki
Cystatin A inhibits IL-8 production by keratinocytes stimulated with Der p 1 and Der f 1: biochemical skin barrier against mite cysteine proteases.
The Journal of allergy and clinical immunology 2005;116(1):169-76.
2005: Nishiyama Chiharu; Ito Tomonobu; Nishiyama Makoto; Masaki Shigehiro; Maeda Keiko; Nakano Nobuhiro; Ng William; Fukuyama Kanako; Yamamoto Masayuki; Okumura Ko; Ogawa Hideoki
GATA-1 is required for expression of Fc{epsilon}RI on mast cells: analysis of mast cells derived from GATA-1 knockdown mouse bone marrow.
International immunology 2005;17(7):847-56.
2005: Bashuda Hisashi; Kimikawa Masaaki; Seino Kenichiro; Kato Yojiro; Ono Fumiko; Shimizu Akira; Yagita Hideo; Teraoka Satoshi; Okumura Ko
Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates.
The Journal of clinical investigation 2005;115(7):1896-902.
2005: Takai Toshiro; Kato Takeshi; Ota Mikiko; Yasueda Hiroshi; Kuhara Takatoshi; Okumura Ko; Ogawa Hideoki
Recombinant Der p 1 and Der f 1 with in vitro enzymatic activity to cleave human CD23, CD25 and alpha1-antitrypsin, and in vivo IgE-eliciting activity in mice.
International archives of allergy and immunology 2005;137(3):194-200.
2005: Ota Tsuyoshi; Takeda Kazuyoshi; Akiba Hisaya; Hayakawa Yoshihiro; Ogasawara Kouetsu; Ikarashi Yoshinori; Miyake Sachiko; Wakasugi Hiro; Yamamura Takashi; Kronenberg Mitchell; Raulet David H; Kinoshita Katsuyuki; Yagita Hideo; Smyth Mark J; Okumura Ko
IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.
Blood 2005;106(1):184-92.
2005: Kawada Hiroshi; Nishiyama Chiharu; Takagi Atsushi; Tokura Tomoko; Nakano Nobuhiro; Maeda Keiko; Mayuzumi Nobuyasu; Ikeda Shigaku; Okumura Ko; Ogawa Hideoki
Transcriptional regulation of ATP2C1 gene by Sp1 and YY1 and reduced function of its promoter in Hailey-Hailey disease keratinocytes.
The Journal of investigative dermatology 2005;124(6):1206-14.
2005: Totsuka Teruji; Kanai Takanori; Makita Shin; Fujii Rei; Nemoto Yasuhiro; Oshima Shigeru; Okamoto Ryuichi; Koyanagi Akemi; Akiba Hisaya; Okumura Ko; Yagita Hideo; Watanabe Mamoru
Regulation of murine chronic colitis by CD4+CD25- programmed death-1+ T cells.
European journal of immunology 2005;35(6):1773-85.
2005: Tanaka Toshitaka; Ebata Tomohiko; Tajima Atsushi; Kinoshita Katsuyuki; Okumura Ko; Yagita Hideo
Beta2-microglobulin required for cell surface expression of blastocyst MHC.
Biochemical and biophysical research communications 2005;332(1):311-7.
2005: Kaduka Yuki; Takeda Kazuyoshi; Nakayama Masafumi; Kinoshita Katsuyuki; Yagita Hideo; Okumura Ko
TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage.
Biochemical and biophysical research communications 2005;331(2):384-90.
2005: Aramaki O; Inoue F; Takayama T; Shimazu M; Kitajima M; Ikeda Y; Okumura K; Yagita H; Shirasugi N; Niimi M
Various costimulatory pathways are essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplantation proceedings 2005;37(4):1934-6.
2005: Takai Toshiro; Takaoka Masatoshi; Yasueda Hiroshi; Okumura Ko; Ogawa Hideoki
Dilution method to refold bacterially expressed recombinant Der f 2 and Der p 2 to exhibit the secondary structure and histamine-releasing activity of natural allergens.
International archives of allergy and immunology 2005;137(1):1-8.
2005: Tsukahara Rintaro; Takeuchi Masaru; Akiba Hisaya; Kezuka Takeshi; Takeda Kazuyoshi; Usui Yoshihiko; Usui Masahiko; Yagita Hideo; Okumura Ko
Critical contribution of CD80 and CD86 to induction of anterior chamber-associated immune deviation.
International immunology 2005;17(5):523-30.
2005: Kimura Hiroko; Nagao Fumiko; Tanaka Yukio; Sakai Shizu; Ohnishi S Tsuyoshi; Okumura Ko
Beneficial effects of the Nishino breathing method on immune activity and stress level.
Journal of alternative and complementary medicine (New York, N.Y.) 2005;11(2):285-91.
2005: Kanamaru Yutaka; Sumiyoshi Koji; Ushio Hiroko; Ogawa Hideoki; Okumura Ko; Nakao Atsuhito
Smad3 deficiency in mast cells provides efficient host protection against acute septic peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4193-7.
2005: Nakazawa Takuya; Takai Toshiro; Hatanaka Hideki; Mizuuchi Eri; Nagamune Teruyuki; Okumura Ko; Ogawa Hideoki
Multiple-mutation at a potential ligand-binding region decreased allergenicity of a mite allergen Der f 2 without disrupting global structure.
FEBS letters 2005;579(9):1988-94.
2005: Takai Toshiro; Kato Takeshi; Yasueda Hiroshi; Okumura Ko; Ogawa Hideoki
Analysis of the structure and allergenicity of recombinant pro- and mature Der p 1 and Der f 1: major conformational IgE epitopes blocked by prodomains.
The Journal of allergy and clinical immunology 2005;115(3):555-63.
2005: Aramaki Osamu; Inoue Fumihiko; Takayama Tadatoshi; Shimazu Motohide; Kitajima Masaki; Ikeda Yoshifumi; Okumura Ko; Yagita Hideo; Shirasugi Nozomu; Niimi Masanori
Interleukin-10 but not transforming growth factor-beta is essential for generation and suppressor function of regulatory cells induced by intratracheal delivery of alloantigen.
Transplantation 2005;79(5):568-76.
2005: Takai Toshiro; Kato Takeshi; Sakata Yasuhisa; Yasueda Hiroshi; Izuhara Kenji; Okumura Ko; Ogawa Hideoki
Recombinant Der p 1 and Der f 1 exhibit cysteine protease activity but no serine protease activity.
Biochemical and biophysical research communications 2005;328(4):944-52.
2005: Nakano Nobuhiro; Nishiyama Chiharu; Masuoka Nobutaka; Nishiyama Makoto; Yamane Hisakazu; Okumura Ko; Ogawa Hideoki
Analysis of PU.1/ICSBP (IRF-8) complex formation with various PU.1 mutants: molecular cloning of rat Icsbp (Irf-8) cDNA.
Immunogenetics 2005;56(12):871-7.
2005: Takeda Kazuyoshi; Cretney Erika; Hayakawa Yoshihiro; Ota Tsuyoshi; Akiba Hisaya; Ogasawara Kouetsu; Yagita Hideo; Kinoshita Katsuyuki; Okumura Ko; Smyth Mark J
TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.
Blood 2005;105(5):2082-9.
2005: Kaneda Hiroshi; Takeda Kazuyoshi; Ota Tsuyoshi; Kaduka Yuki; Akiba Hisaya; Ikarashi Yoshinori; Wakasugi Hiro; Kronenberg Mitchell; Kinoshita Katsuyuki; Yagita Hideo; Okumura Ko
ICOS costimulates invariant NKT cell activation.
Biochemical and biophysical research communications 2005;327(1):201-7.
2005: Ito Tomonobu; Nishiyama Chiharu; Nishiyama Makoto; Matsuda Hironori; Maeda Keiko; Akizawa Yushiro; Tsuboi Ryoji; Okumura Ko; Ogawa Hideoki
Mast cells acquire monocyte-specific gene expression and monocyte-like morphology by overproduction of PU.1.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):376-83.
2005: Mehmut Murat; Takeda Kazuyoshi; Abe Masaaki; Ogata Hideko; Hirose Sachiko; Okumura Ko; Fujime Makoto
Fas ligand and TNF-related apoptosis-inducing ligand induction on infiltrating lymphocytes in bladder carcinoma by bacillus Calmette-Guérin treatment.
Urologia internationalis 2005;75(1):80-7.
2004: Nishiyama Chiharu; Akizawa Yushiro; Nishiyama Makoto; Tokura Tomoko; Kawada Hiroshi; Mitsuishi Kouichi; Hasegawa Masanari; Ito Tomonobu; Nakano Nobuhiro; Okamoto Atsushi; Takagi Atsushi; Yagita Hideo; Okumura Ko; Ogawa Hideoki
Polymorphisms in the Fc epsilon RI beta promoter region affecting transcription activity: a possible promoter-dependent mechanism for association between Fc epsilon RI beta and atopy.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6458-64.
2004: Kasuga Chinatsu; Ebata Tomohiko; Kayagaki Nobuhiko; Yagita Hideo; Hishii Makoto; Arai Hajime; Sato Kiyoshi; Okumura Ko
Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kappaB inhibitors.
Cancer science 2004;95(10):840-4.
2004: Yagita Hideo; Takeda Kazuyoshi; Hayakawa Yoshihiro; Smyth Mark J; Okumura Ko
TRAIL and its receptors as targets for cancer therapy.
Cancer science 2004;95(10):777-83.
2004: Ushio Hiroko; Nakao Atsuhito; Supajatura Volaluck; Miyake Kensuke; Okumura Ko; Ogawa Hideoki
MD-2 is required for the full responsiveness of mast cells to LPS but not to PGN.
Biochemical and biophysical research communications 2004;323(2):491-8.
2004: Nishiyama Chiharu; Masuoka Nobutaka; Nishiyama Makoto; Ito Tomonobu; Yamane Hisakazu; Okumura Ko; Ogawa Hideoki
Evidence against requirement of Ser41 and Ser45 for function of PU.1 -- molecular cloning of rat PU.1.
FEBS letters 2004;572(1-3):57-64.
2004: Inazaki Kumi; Kanamaru Yutaka; Kojima Yuko; Sueyoshi Noriyoshi; Okumura Ko; Kaneko Kazunari; Yamashiro Yuichiro; Ogawa Hideoki; Nakao Atsuhito
Smad3 deficiency attenuates renal fibrosis, inflammation,and apoptosis after unilateral ureteral obstruction.
Kidney international 2004;66(2):597-604.
2004: Sumiyoshi Koji; Nakao Atsuhito; Setoguchi Yasuhiro; Okumura Ko; Ogawa Hideoki
Exogenous Smad3 accelerates wound healing in a rabbit dermal ulcer model.
The Journal of investigative dermatology 2004;123(1):229-36.
2004: Sasazuki Tomonari; Okazaki Tatsuma; Tada Kurisu; Sakon-Komazawa Sachiko; Katano Mitsuo; Tanaka Masao; Yagita Hideo; Okumura Ko; Tominaga Naoko; Hayashizaki Yoshihide; Okazaki Yasushi; Nakano Hiroyasu
Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes are induced by TNF and responsible for elimination of ROS.
Molecular immunology 2004;41(5):547-51.
2004: Jin Long; Nakao Atsuhito; Nakayama Masafumi; Yamaguchi Noriko; Kojima Yuko; Nakano Nobuhiro; Tsuboi Ryoji; Okumura Ko; Yagita Hideo; Ogawa Hideoki
Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes.
The Journal of investigative dermatology 2004;122(5):1175-9.
2004: Nishiyama Chiharu; Nishiyama Makoto; Ito Tomonobu; Masaki Shigehiro; Masuoka Nobutaka; Yamane Hisakazu; Kitamura Toshio; Ogawa Hideoki; Okumura Ko
Functional analysis of PU.1 domains in monocyte-specific gene regulation.
FEBS letters 2004;561(1-3):63-8.
2004: Takeda Kazuyoshi; Yamaguchi Noriko; Akiba Hisaya; Kojima Yuko; Hayakawa Yoshihiro; Tanner Jane E; Sayers Thomas J; Seki Naoko; Okumura Ko; Yagita Hideo; Smyth Mark J
Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.
The Journal of experimental medicine 2004;199(4):437-48.
2004: Seko Yoshinori; Sugishita Kazuyuki; Sato Osamu; Takagi Atsuhiko; Tada Yusuke; Matsuo Hiroshi; Yagita Hideo; Okumura Ko; Nagai Ryozo
Expression of costimulatory molecules (4-1BBL and Fas) and major histocompatibility class I chain-related A (MICA) in aortic tissue with Takayasu's arteritis.
Journal of vascular research 2004;41(1):84-90.
2004: Aramaki Osamu; Shirasugi Nozomu; Takayama Tadatoshi; Shimazu Motohide; Kitajima Masaki; Ikeda Yoshifumi; Azuma Miyuki; Okumura Ko; Yagita Hideo; Niimi Masanori
Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen.
Transplantation 2004;77(1):6-12.
2004: Nishiyama Chiharu; Nishiyama Makoto; Ito Tomonobu; Masaki Shigehiro; Maeda Keiko; Masuoka Nobutaka; Yamane Hisakazu; Kitamura Toshio; Ogawa Hideoki; Okumura Ko
Overproduction of PU.1 in mast cell progenitors: its effect on monocyte- and mast cell-specific gene expression.
Biochemical and biophysical research communications 2004;313(3):516-21.
2004: Kudo Takahiro; Nagata Satoru; Aoyagi Yo; Suzuki Ryuyo; Matsuda Hironori; Ohtsuka Yoshikazu; Shimizu Toshiaki; Okumura Ko; Yamashiro Yuichiro
Polarized production of T-helper cell type 1 cells in Peyer's patches in Crohn's disease.
Digestion 2004;70(4):214-25.
2003: Miyahira Yasushi; Akiba Hisaya; Katae Masaharu; Kubota Kaori; Kobayashi Seiki; Takeuchi Tsutomu; García-Sastre Adolfo; Fukuchi Yoshinosuke; Okumura Ko; Yagita Hideo; Aoki Takashi
Cutting edge: a potent adjuvant effect of ligand to receptor activator of NF-kappa B gene for inducing antigen-specific CD8+ T cell response by DNA and viral vector vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6344-8.
2003: Miyahira Yasushi; Akiba Hisaya; Ogawa Shu-Hei; Ishi Tomohiro; Watanabe Shiho; Kobayashi Seiki; Takeuchi Tsutomu; Aoki Takashi; Tezuka Katsunari; Abe Ryo; Okumura Ko; Yagita Hideo; Watanabe Naohiro
Involvement of ICOS-B7RP-1 costimulatory pathway in the regulation of immune responses to Leishmania major and Nippostrongylus brasiliensis infections.
Immunology letters 2003;89(2-3):193-9.
2003: Kanai Takanori; Totsuka Teruji; Uraushihara Koji; Makita Shin; Nakamura Tetsuya; Koganei Kazutaka; Fukushima Tsuneo; Akiba Hisaya; Yagita Hideo; Okumura Ko; Machida Utako; Iwai Hideyuki; Azuma Miyuki; Chen Lieping; Watanabe Mamoru
Blockade of B7-H1 suppresses the development of chronic intestinal inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):4156-63.
2003: Wongpiyabovorn Jongkonnee; Suto Hajime; Ushio Hiroko; Izuhara Kenji; Mitsuishi Koichi; Ikeda Shigaku; Nakao Atsuhito; Okumura Ko; Ogawa Hideoki
Up-regulation of interleukin-13 receptor alpha1 on human keratinocytes in the skin of psoriasis and atopic dermatitis.
Journal of dermatological science 2003;33(1):31-40.
2003: Tsuge T; Suzuki Y; Shimokawa T; Horikoshi S; Okumura K; Ra C; Tomino Y
Monocyte chemoattractant protein (MCP)-1 production via functionally reconstituted Fcalpha receptor (CD89) on glomerular mesangial cells.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52(10):428-32.
2003: Tsushima Fumihiko; Iwai Hideyuki; Otsuki Noriko; Abe Masaaki; Hirose Sachiko; Yamazaki Tomohide; Akiba Hisaya; Yagita Hideo; Takahashi Yuzo; Omura Ken; Okumura Ko; Azuma Miyuki
Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses.
European journal of immunology 2003;33(10):2773-82.
2003: Dan N; Kanai T; Totsuka T; Iiyama R; Yamazaki M; Sawada T; Miyata T; Yagita H; Okumura K; Watanabe M
Ameliorating effect of anti-Fas ligand MAb on wasting disease in murine model of chronic colitis.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(4):G754-60.
2003: Hirano Takao; Miyajima Hiroaki; Tateno Masatoshi; Oshimi Kazuo; Okumura Ko
[The chimerism and GVT effects on murine mini-transplantation model]
Nippon rinsho. Japanese journal of clinical medicine 2003;61(9):1527-34.
2003: Sumiyoshi K; Nakao A; Setoguchi Y; Okumura K; Tsuboi R; Ogawa H
Smads regulate collagen gel contraction by human dermal fibroblasts.
The British journal of dermatology 2003;149(3):464-70.
2003: Aramaki Osamu; Shirasugi Nozomu; Akiyama Yoshinobu; Shibutani Shintaro; Takayama Tadatoshi; Shimazu Motohide; Kitajima Masaki; Ikeda Yoshifumi; Okumura Ko; Yagita Hideo; Niimi Masanori
CD27/CD70, CD134/CD134 ligand, and CD30/CD153 pathways are independently essential for generation of regulatory cells after intratracheal delivery of alloantigen.
Transplantation 2003;76(5):772-6.
2003: Iwai Hideyuki; Abe Masaaki; Hirose Sachiko; Tsushima Fumihiko; Tezuka Katsunari; Akiba Hisaya; Yagita Hideo; Okumura Ko; Kohsaka Hitoshi; Miyasaka Nobuyuki; Azuma Miyuki
Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):2848-54.
2003: Hasegawa Masanari; Nishiyama Chiharu; Nishiyama Makoto; Akizawa Yushiro; Mitsuishi Kouichi; Ito Tomonobu; Kawada Hiroshi; Furukawa Susumu; Ra Chisei; Okumura Ko; Ogawa Hideoki
A novel -66T/C polymorphism in Fc epsilon RI alpha-chain promoter affecting the transcription activity: possible relationship to allergic diseases.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1927-33.
2003: Tajima Atsushi; Tanaka Toshitaka; Ebata Tomohiko; Takeda Kazuyoshi; Kawasaki Akemi; Kelly Janice M; Darcy Phillip K; Vance Russell E; Raulet David H; Kinoshita Katsuyuki; Okumura Ko; Smyth Mark J; Yagita Hideo
Blastocyst MHC, a putative murine homologue of HLA-G, protects TAP-deficient tumor cells from natural killer cell-mediated rejection in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1715-21.
2003: Sakon Sachiko; Xue Xin; Takekawa Mutsuhiro; Sasazuki Tomonari; Okazaki Tatsuma; Kojima Yuko; Piao Jian-Hu; Yagita Hideo; Okumura Ko; Doi Takahiro; Nakano Hiroyasu
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death.
The EMBO journal 2003;22(15):3898-909.
2003: Nakayama Masafumi; Harada Norihiro; Okumura Ko; Yagita Hideo
Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies.
Biochemical and biophysical research communications 2003;306(4):819-25.
2003: Yokoi H; Seki M; Okazoe S; Okumura K; Yoshikawa H
The role and expression of CD27 and CD70 lymphocytes in the human tonsil.
Lymphology 2003;36(2):74-83.
2003: Miyahira Yasushi; Katae Masaharu; Kobayashi Seiki; Takeuchi Tsutomu; Fukuchi Yoshinosuke; Abe Ryo; Okumura Ko; Yagita Hideo; Aoki Takashi
Critical contribution of CD28-CD80/CD86 costimulatory pathway to protection from Trypanosoma cruzi infection.
Infection and immunity 2003;71(6):3131-7.
2003: Shirasugi Nozomu; Akiyama Yoshinobu; Aramaki Osamu; Shibutani Sintaro; Matsumoto Kenji; Bashuda Hisashi; Yagita Hideo; Okumura Ko; Ikeda Yoshifumi; Niimi Masanori
Role of the CTLA4 pathway in hyporesponsiveness induced by intratracheal delivery of alloantigen.
Transplantation 2003;75(10):1636-9.
2003: Akizawa Yushiro; Nishiyama Chiharu; Hasegawa Masanari; Maeda Keiko; Nakahata Tatsutoshi; Okumura Ko; Ra Chisei; Ogawa Hideoki
Regulation of human FcepsilonRI beta chain gene expression by Oct-1.
International immunology 2003;15(5):549-56.
2003: Hasegawa Masanari; Nishiyama Chiharu; Nishiyama Makoto; Akizawa Yushiro; Takahashi Kyoko; Ito Tomonobu; Furukawa Susumu; Ra Chisei; Okumura Ko; Ogawa Hideoki
Regulation of the human Fc epsilon RI alpha-chain distal promoter.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(7):3732-8.
2003: Totsuka T; Kanai T; Uraushihara K; Iiyama R; Yamazaki M; Akiba H; Yagita H; Okumura K; Watanabe M
Therapeutic effect of anti-OX40L and anti-TNF-alpha MAbs in a murine model of chronic colitis.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(4):G595-603.
2003: Nishiyama Chiharu; Yokota Toyokazu; Nishiyama Makoto; Ra Chisei; Okumura Ko; Ogawa Hideoki
Molecular cloning of rat transcription factor YY1.
Bioscience, biotechnology, and biochemistry 2003;67(3):654-8.
2003: Funaki Toshinari; Nakao Atsuhito; Ebihara Nobuyuki; Setoguchi Yasuhiro; Fukuchi Yoshinosuke; Okumura Ko; Ra Chisei; Ogawa Hideoki; Kanai Atsushi
Smad7 suppresses the inhibitory effect of TGF-beta2 on corneal endothelial cell proliferation and accelerates corneal endothelial wound closure in vitro.
Cornea 2003;22(2):153-9.
2003: Miyahira Yasushi; Katae Masaharu; Takeda Kazuyoshi; Yagita Hideo; Okumura Ko; Kobayashi Seiki; Takeuchi Tsutomu; Kamiyama Tsuneo; Fukuchi Yoshinosuke; Aoki Takashi
Activation of natural killer T cells by alpha-galactosylceramide impairs DNA vaccine-induced protective immunity against Trypanosoma cruzi.
Infection and immunity 2003;71(3):1234-41.
2003: Sumiyoshi Koji; Nakao Atsuhito; Setoguchi Yasuhiro; Tsuboi Ryoji; Okumura Ko; Ogawa Hideoki
TGF-beta/Smad signaling inhibits IFN-gamma and TNF-alpha-induced TARC (CCL17) production in HaCaT cells.
Journal of dermatological science 2003;31(1):53-8.
2003: Totsuka Teruji; Kanai Takanori; Iiyama Ryoichi; Uraushihara Koji; Yamazaki Motomi; Okamoto Ryuichi; Hibi Toshifumi; Tezuka Katsunari; Azuma Miyuki; Akiba Hisaya; Yagita Hideo; Okumura Ko; Watanabe Mamoru
Ameliorating effect of anti-inducible costimulator monoclonal antibody in a murine model of chronic colitis.
Gastroenterology 2003;124(2):410-21.
2003: Okazaki Tatsuma; Sakon Sachiko; Sasazuki Tomonari; Sakurai Hiroaki; Doi Takahiro; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses.
Biochemical and biophysical research communications 2003;300(4):807-12.
2003: Muto T; Hsieh S D; Sakurai Y; Yoshinaga H; Suto H; Okumura K; Ogawa H
Prevalence of atopic dermatitis in Japanese adults.
The British journal of dermatology 2003;148(1):117-21.
2003: Nakayama Masafumi; Ishidoh Kazumi; Kojima Yuko; Harada Norihiro; Kominami Eiki; Okumura Ko; Yagita Hideo
Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):341-8.
2003: Maeda Keiko; Nishiyama Chiharu; Tokura Tomoko; Akizawa Yushiro; Nishiyama Makoto; Ogawa Hideoki; Okumura Ko; Ra Chisei
Regulation of cell type-specific mouse Fc epsilon RI beta-chain gene expression by GATA-1 via four GATA motifs in the promoter.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):334-40.
2003: Kanamaru Yutaka; Nakao Atsuhito; Tanaka Yuichi; Inagaki Yutaka; Ushio Hiroko; Shirato Isao; Horikoshi Satoshi; Okumura Ko; Ogawa Hideoki; Tomino Yasuhiko
Involvement of p300 in TGF-beta/Smad-pathway-mediated alpha2(I) collagen expression in mouse mesangial cells.
Nephron. Experimental nephrology 2003;95(1):e36-42.
2002: Nakao Atsuhito; Sagara Hironori; Setoguchi Yasuhiro; Okada Takenori; Okumura Ko; Ogawa Hideoki; Fukuda Takeshi
Expression of Smad7 in bronchial epithelial cells is inversely correlated to basement membrane thickness and airway hyperresponsiveness in patients with asthma.
The Journal of allergy and clinical immunology 2002;110(6):873-8.
2002: Uchida Takafumi; Suto Hajime; Ra Chisei; Ogawa Hideoki; Kobata Tetsuji; Okumura Ko
Preferential expression of T(h)2-type chemokine and its receptor in atopic dermatitis.
International immunology 2002;14(12):1431-8.
2002: Harada Norihiro; Nakayama Masafumi; Nakano Hiroyasu; Fukuchi Yoshinosuke; Yagita Hideo; Okumura Ko
Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells.
Biochemical and biophysical research communications 2002;299(3):488-93.
2002: Yamazaki Tomohide; Akiba Hisaya; Iwai Hideyuki; Matsuda Hironori; Aoki Mami; Tanno Yuka; Shin Tahiro; Tsuchiya Haruo; Pardoll Drew M; Okumura Ko; Azuma Miyuki; Yagita Hideo
Expression of programmed death 1 ligands by murine T cells and APC.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5538-45.
2002: Takai Toshiro; Mineki Reiko; Nakazawa Takuya; Takaoka Masatoshi; Yasueda Hiroshi; Murayama Kimie; Okumura Ko; Ogawa Hideoki
Maturation of the activities of recombinant mite allergens Der p 1 and Der f 1, and its implication in the blockade of proteolytic activity.
FEBS letters 2002;531(2):265-72.
2002: Kayagaki Nobuhiko; Yamaguchi Noriko; Abe Masaaki; Hirose Sachiko; Shirai Toshikazu; Okumura Ko; Yagita Hideo
Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL).
Cellular immunology 2002;219(2):82-91.
2002: Akiyama Yoshinobu; Shirasugi Nozomu; Uchida Norio; Matsumoto Kenji; Kitajima Masaki; Bashuda Hisashi; Yagita Hideo; Okumura Ko; Aramaki Osamu; Niimi Masanori
B7/CTLA4 pathway is essential for generating regulatory cells after intratracheal delivery of alloantigen in mice.
Transplantation 2002;74(5):732-8.
2002: Katae Masaharu; Miyahira Yasushi; Takeda Kazuyoshi; Matsuda Hironori; Yagita Hideo; Okumura Ko; Takeuchi Tsutomu; Kamiyama Tsuneo; Ohwada Akihiko; Fukuchi Yoshinosuke; Aoki Takashi
Coadministration of an interleukin-12 gene and a Trypanosoma cruzi gene improves vaccine efficacy.
Infection and immunity 2002;70(9):4833-40.
2002: Kojima Yuko; Kawasaki-Koyanagi Akemi; Sueyoshi Noriyoshi; Kanai Atsushi; Yagita Hideo; Okumura Ko
Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity.
Biochemical and biophysical research communications 2002;296(2):328-36.
2002: Sasazuki Tomonari; Sawada Taisuke; Sakon Sachiko; Kitamura Toshio; Kishi Takuma; Okazaki Tatsuma; Katano Mitsuo; Tanaka Masao; Watanabe Mamoru; Yagita Hideo; Okumura Ko; Nakano Hiroyasu
Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death.
The Journal of biological chemistry 2002;277(32):28853-60.
2002: Ebihara Nobuyuki; Okumura Ko; Nakayasu Kiyoo; Kanai Atsushi; Ra Chisei
High level of Fc epsilon receptor I-bindable immunoglobulin E in the tear fluid and increased immunoglobulin E-saturated cells in the giant papillae of vernal keratoconjunctivitis patients.
Japanese journal of ophthalmology 2002;46(4):357-63.
2002: Kanamaru Yutaka; Nakao Atsuhito; Shirato Isao; Okumura Ko; Ogawa Hideoki; Tomino Yasuhiko; Ra Chisei
Chronic graft-versus-host autoimmune disease in Fc receptor gamma chain-deficient mice results in lipoprotein glomerulopathy.
Journal of the American Society of Nephrology : JASN 2002;13(6):1527-33.
2002: Nishiyama Chiharu; Takahashi Kyoko; Ohtake Yasuyuki; Yokota Toyokazu; Okumura Ko; Ogawa Hideoki; Ra Chisei
Analysis of transactivation region of Elf-1 by using a yeast one-hybrid system.
Bioscience, biotechnology, and biochemistry 2002;66(5):1105-7.
2002: Miyajima Hiroaki; Watanabe Naohiro; Ovary Zoltan; Okumura Ko; Hirano Takao
Rat monoclonal anti-murine IgE antibody removes IgE molecules already bound to mast cells or basophilic leukemia cells, resulting in the inhibition of systemic anaphylaxis and passive cutaneous anaphylaxis.
International archives of allergy and immunology 2002;128(1):24-32.
2002: Seko Yoshinori; Ishiyama Shigeru; Nishikawa Toshiro; Kasajima Takeshi; Hiroe Michiaki; Suzuki Shin; Ishiwata Sugao; Kawai Sachio; Tanaka Yuetsu; Azuma Miyuki; Kobata Tetsuji; Yagita Hideo; Okumura Ko; Nagai Ryozo
Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, OX40L and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2002;11(3):166-70.
2002: Supajatura Volaluck; Ushio Hiroko; Nakao Atsuhito; Akira Shizuo; Okumura Ko; Ra Chisei; Ogawa Hideoki
Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity.
The Journal of clinical investigation 2002;109(10):1351-9.
2002: Nishiyama Chiharu; Hasegawa Masanari; Nishiyama Makoto; Takahashi Kyoko; Akizawa Yushiro; Yokota Toyokazu; Okumura Ko; Ogawa Hideoki; Ra Chisei
Regulation of human Fc epsilon RI alpha-chain gene expression by multiple transcription factors.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4546-52.
2002: Seko Yoshinori; Kayagaki Nobuhiko; Seino Ken-ichiro; Yagita Hideo; Okumura Ko; Nagai Ryozo
Role of Fas/FasL pathway in the activation of infiltrating cells in murine acute myocarditis caused by Coxsackievirus B3.
Journal of the American College of Cardiology 2002;39(8):1399-403.
2002: Suzuki Ryuyo; Nakao Atsuhito; Kanamaru Yutaka; Okumura Ko; Ogawa Hideoki; Ra Chisei
Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta.
International immunology 2002;14(4):339-45.
2002: Yamada Masato; Yagita Hideo; Inoue Hideko; Takanashi Tsuyoshi; Matsuda Hironori; Munechika Eiko; Kanamaru Yutaka; Shirato Isao; Tomino Yasuhiko; Matushima Kouji; Okumura Ko; Hashimoto Hiroshi
Selective accumulation of CCR4+ T lymphocytes into renal tissue of patients with lupus nephritis.
Arthritis and rheumatism 2002;46(3):735-40.
2002: Supajatura Volaluck; Ushio Hiroko; Wada Akihiro; Yahiro Kinnosuke; Okumura Ko; Ogawa Hideoki; Hirayama Toshiya; Ra Chisei
Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):2603-7.
2002: Futagawa Toshiro; Akiba Hisaya; Kodama Tomohiro; Takeda Kazuyoshi; Hosoda Yasuyuki; Yagita Hideo; Okumura Ko
Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells.
International immunology 2002;14(3):275-86.
2002: Sumiyoshi K; Nakao A; Ushio H; Mitsuishi K; Okumura K; Tsuboi R; Ra C; Ogawa H
Transforming growth factor-beta1 suppresses atopic dermatitis-like skin lesions in NC/Nga mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(2):309-14.
2002: Kobayashi Noriyoshi; Suzuki Yusuke; Tsuge Toshinao; Okumura Ko; Ra Chisei; Tomino Yasuhiko
FcRn-mediated transcytosis of immunoglobulin G in human renal proximal tubular epithelial cells.
American journal of physiology. Renal physiology 2002;282(2):F358-65.
2002: Kagaya Fumie; Hori Junko; Kamiya Kazutaka; Kaji Yuichi; Oshika Tetsuro; Amano Shiro; Yamagami Satoru; Tsuru Tadahiko; Tanaka Sumiyoshi; Matsuda Hironori; Yagita Hideo; Okumura Ko
Inhibition of murine corneal allograft rejection by treatment with antibodies to CD80 and CD86.
Experimental eye research 2002;74(1):131-9.
2002: Takeda Kazuyoshi; Smyth Mark J; Cretney Erika; Hayakawa Yoshihiro; Kayagaki Nobuhiko; Yagita Hideo; Okumura Ko
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development.
The Journal of experimental medicine 2002;195(2):161-9.
2002: Nakayama Masafumi; Ishidoh Kazumi; Kayagaki Nobuhiko; Kojima Yuko; Yamaguchi Noriko; Nakano Hiroyasu; Kominami Eiki; Okumura Ko; Yagita Hideo
Multiple pathways of TWEAK-induced cell death.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):734-43.
2001: Takeda K; Smyth M J; Cretney E; Hayakawa Y; Yamaguchi N; Yagita H; Okumura K
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth.
Cellular immunology 2001;214(2):194-200.
2001: Seko Y; Takahashi N; Oshima H; Shimozato O; Akiba H; Takeda K; Kobata T; Yagita H; Okumura K; Azuma M; Nagai R
Expression of tumour necrosis factor (TNF) ligand superfamily co-stimulatory molecules CD30L, CD27L, OX40L, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3.
The Journal of pathology 2001;195(5):593-603.
2001: Sato K; Hida S; Takayanagi H; Yokochi T; Kayagaki N; Takeda K; Yagita H; Okumura K; Tanaka N; Taniguchi T; Ogasawara K
Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta.
European journal of immunology 2001;31(11):3138-46.
2001: Nozawa K; Ohata J; Sakurai J; Hashimoto H; Miyajima H; Yagita H; Okumura K; Azuma M
Preferential blockade of CD8(+) T cell responses by administration of anti-CD137 ligand monoclonal antibody results in differential effect on development of murine acute and chronic graft-versus-host diseases.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):4981-6.
2001: Uchida T; Nakao A; Nakano N; Kuramasu A; Saito H; Okumura K; Ra C; Ogawa H
Identification of Nash1, a novel protein containing a nuclear localization signal, a sterile alpha motif, and an SH3 domain preferentially expressed in mast cells.
Biochemical and biophysical research communications 2001;288(1):137-41.
2001: Takeda K; Okumura K
[Current advances and expectations in tumor immunology]
Human cell : official journal of Human Cell Research Society 2001;14(3):159-63.
2001: Tada K; Okazaki T; Sakon S; Kobarai T; Kurosawa K; Yamaoka S; Hashimoto H; Mak T W; Yagita H; Okumura K; Yeh W C; Nakano H
Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death.
The Journal of biological chemistry 2001;276(39):36530-4.
2001: Supajatura V; Ushio H; Nakao A; Okumura K; Ra C; Ogawa H
Protective roles of mast cells against enterobacterial infection are mediated by Toll-like receptor 4.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):2250-6.
2001: Okazaki T; Nakao A; Nakano H; Takahashi F; Takahashi K; Shimozato O; Takeda K; Yagita H; Okumura K
Impairment of bleomycin-induced lung fibrosis in CD28-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):1977-81.
2001: Nishiyama C; Hasegawa M; Nishiyama M; Takahashi K; Yokota T; Okumura K; Ra C
Cloning of full-length genomic DNA encoding human FcepsilonRI alpha-chain and its transcriptional regulation.
Biochemical and biophysical research communications 2001;284(4):1056-64.
2001: Ebata T; Mogi S; Hata Y; Fujimoto J I; Yagita H; Okumura K; Azuma M
Rapid induction of CD95 ligand and CD4+ T cell-mediated apoptosis by CD137 (4-1BB) costimulation.
European journal of immunology 2001;31(5):1410-6.
2001: Shirasugi N; Ikeda Y; Akiyama Y; Matsumoto K; Hamano K; Esato K; Bashuda H; Yagita H; Okumura K; Takami H; Kodaira S; Niimi M
Induction of hyporesponsiveness to fully allogeneic cardiac grafts by intratracheal delivery of alloantigen.
Transplantation 2001;71(4):561-4.
2001: Kanamaru Y; Nakao A; Mamura M; Suzuki Y; Shirato I; Okumura K; Tomino Y; Ra C
Blockade of TGF-beta signaling in T cells prevents the development of experimental glomerulonephritis.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2818-23.
2001: Nohara C; Akiba H; Nakajima A; Inoue A; Koh C S; Ohshima H; Yagita H; Mizuno Y; Okumura K
Amelioration of experimental autoimmune encephalomyelitis with anti-OX40 ligand monoclonal antibody: a critical role for OX40 ligand in migration, but not development, of pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):2108-15.
2001: Takai T; Okumura K; Ra C
Direct expression of the extracellular portion of human FcepsilonRIalpha chain as inclusion bodies in Escherichia coli.
Bioscience, biotechnology, and biochemistry 2001;65(1):79-85.
2001: Takeda K; Hayakawa Y; Smyth M J; Kayagaki N; Yamaguchi N; Kakuta S; Iwakura Y; Yagita H; Okumura K
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.
Nature medicine 2001;7(1):94-100.
2000: Nagao F; Nakayama M; Muto T; Okumura K
Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the immune system in healthy human subjects.
Bioscience, biotechnology, and biochemistry 2000;64(12):2706-8.
2000: Mogi S; Sakurai J; Kohsaka T; Enomoto S; Yagita H; Okumura K; Azuma M
Tumour rejection by gene transfer of 4-1BB ligand into a CD80(+) murine squamous cell carcinoma and the requirements of co-stimulatory molecules on tumour and host cells.
Immunology 2000;101(4):541-7.
2000: Shirasugi N; Matsumoto S; Hamano K; Esato K; Matsumoto K; Bashuda H; Yagita H; Okumura K; Ikeda Y; Takami H; Kodaira S; Niimi M
Survival of fully allogeneic cardiac allografts induced by delivery of alloantigen via respiratory mucosa is abrogated by blockade of the B7 pathway.
Transplantation proceedings 2000;32(7):2034.
2000: Nakayama M; Kayagaki N; Yamaguchi N; Okumura K; Yagita H
Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity.
The Journal of experimental medicine 2000;192(9):1373-80.
2000: Nagao F; Suzui M; Takeda K; Yagita H; Okumura K
Mobilization of NK cells by exercise: downmodulation of adhesion molecules on NK cells by catecholamines.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(4):R1251-6.
2000: Takai T; Yuuki T; Iwamoto-Yasue N; Okumura K; Ra C
Epitope analysis and primary structures of variable regions of anti-human FcepsilonRI monoclonal antibodies, and expression of the chimeric antibodies fused with human constant regions.
Bioscience, biotechnology, and biochemistry 2000;64(9):1856-67.
2000: Shimokawa T; Tsuge T; Okumura K; Ra C
Identification and characterization of the promoter for the gene encoding the human myeloid IgA Fc receptor (FcalphaR, CD89).
Immunogenetics 2000;51(11):945-54.
2000: Seko Y; Takahashi N; Tada Y; Yagita H; Okumura K; Nagai R
Restricted usage of T-cell receptor Vgamma-Vdelta genes and expression of costimulatory molecules in Takayasu's arteritis.
International journal of cardiology 2000;75 Suppl 1():S77-83; discussion S85-7.
2000: Hattori K; Hirano T; Oshimi K; Yagita H; Okumura K
A metalloproteinase inhibitor prevents acute graft-versus-host disease while preserving the graft-versus-leukaemia effect of allogeneic bone marrow transplantation.
Leukemia & lymphoma 2000;38(5-6):553-61.
2000: Noguchi M; Sakamoto N; Okumura K; Sato N; Yamada K; Isobe Y; Kato A; Oshimi K
[CD8-positive diffuse large B-cell lymphoma]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2000;41(7):591-5.
2000: Nakao A; Miike S; Hatano M; Okumura K; Tokuhisa T; Ra C; Iwamoto I
Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity.
The Journal of experimental medicine 2000;192(2):151-8.
2000: Furumoto Y; Hiraoka S; Kawamoto K; Masaki S; Kitamura T; Okumura K; Ra C
Polymorphisms in FcepsilonRI beta chain do not affect IgE-mediated mast cell activation.
Biochemical and biophysical research communications 2000;273(2):765-71.
2000: Takeda K; Hayakawa Y; Atsuta M; Hong S; Van Kaer L; Kobayashi K; Ito M; Yagita H; Okumura K
Relative contribution of NK and NKT cells to the anti-metastatic activities of IL-12.
International immunology 2000;12(6):909-14.
2000: Takeda K; Hayakawa Y; Van Kaer L; Matsuda H; Yagita H; Okumura K
Critical contribution of liver natural killer T cells to a murine model of hepatitis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5498-503.
2000: Tsurui H; Nishimura H; Hattori S; Hirose S; Okumura K; Shirai T
Seven-color fluorescence imaging of tissue samples based on Fourier spectroscopy and singular value decomposition.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(5):653-62.
2000: Satake Y; Akiba H; Takeda K; Atsuta M; Yagita H; Okumura K
Characterization of rat OX40 ligand by monoclonal antibody.
Biochemical and biophysical research communications 2000;270(3):1041-8.
2000: Shimokawa T; Okumura K; Ra C
DNA induces apoptosis in electroporated human promonocytic cell line U937.
Biochemical and biophysical research communications 2000;270(1):94-9.
2000: Tsukada N; Akiba H; Kobata T; Aizawa Y; Yagita H; Okumura K
Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation.
Blood 2000;95(7):2434-9.
2000: Noguchi M; Okumura K; Kato A; Hirano T; Oshimi K
[Rapidly progressive, refractory eosinophilia with a 250,000/microliter eosinophil count]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2000;41(2):135-9.
2000: Kawamura T; Azuma M; Kayagaki N; Shimada S; Yagita H; Okumura K
Fas/Fas ligand-mediated apoptosis of murine Langerhans cells.
Journal of dermatological science 2000;22(2):96-101.
2000: Takeda K; Oshima H; Hayakawa Y; Akiba H; Atsuta M; Kobata T; Kobayashi K; Ito M; Yagita H; Okumura K
CD27-mediated activation of murine NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1741-5.
2000: Okumura K; Fukiyama K
[Hypertension and sudden death]
Nippon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():800-3.
2000: Akiba H; Miyahira Y; Atsuta M; Takeda K; Nohara C; Futagawa T; Matsuda H; Aoki T; Yagita H; Okumura K
Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis.
The Journal of experimental medicine 2000;191(2):375-80.
2000: Sakurai J; Ohata J; Saito K; Miyajima H; Hirano T; Kohsaka T; Enomoto S; Okumura K; Azuma M
Blockade of CTLA-4 signals inhibits Th2-mediated murine chronic graft-versus-host disease by an enhanced expansion of regulatory CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):664-9.
1999: Morita H; Takeda K; Yagita H; Okumura K
Immunosuppressive effect of leukotriene B(4) receptor antagonist in vitro.
Biochemical and biophysical research communications 1999;264(2):321-6.
1999: Kawamura T; Azuma M; Kayagaki N; Shimada S; Yagita H; Okumura K
Fas/Fas ligand-mediated elimination of antigen-bearing Langerhans cells in draining lymph nodes.
The British journal of dermatology 1999;141(2):201-5.
1999: Nakano H; Sakon S; Koseki H; Takemori T; Tada K; Matsumoto M; Munechika E; Sakai T; Shirasawa T; Akiba H; Kobata T; Santee S M; Ware C F; Rennert P D; Taniguchi M; Yagita H; Okumura K
Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9803-8.
1999: Seko Y; Takahashi N; Oshima H; Shimozato O; Akiba H; Kobata T; Yagita H; Okumura K; Azuma M; Yazaki Y
Expression of tumour necrosis factor (TNF) receptor/ligand superfamily co-stimulatory molecules CD40, CD30L, CD27L, and OX40L in murine hearts with chronic ongoing myocarditis caused by coxsackie virus B3.
The Journal of pathology 1999;188(4):423-30.
1999: Kayagaki N; Yamaguchi N; Nakayama M; Takeda K; Akiba H; Tsutsui H; Okamura H; Nakanishi K; Okumura K; Yagita H
Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):1906-13.
1999: Ebihara N; Yokoyama T; Kimura T; Nakayasu K; Okumura K; Kanai A; Ra C
Anti VLA-4 monoclonal antibody inhibits eosinophil infiltration in allergic conjunctivitis model of guinea pig.
Current eye research 1999;19(1):20-5.
1999: Hattori K; Hirano T; Ushiyama C; Miyajima H; Yamakawa N; Ikeda S; Yoshino K; Tateno M; Oshimi K; Kayagaki N; Yagita H; Okumura K
A metalloproteinase inhibitor prevents acute graft-versus-host disease in mice after bone marrow transplantation.
Bone marrow transplantation 1999;23(12):1283-9.
1999: Akiba H; Oshima H; Takeda K; Atsuta M; Nakano H; Nakajima A; Nohara C; Yagita H; Okumura K
CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7058-66.
1999: Seko Y; Takahashi N; Yagita H; Okumura K; Azuma M; Yazaki Y
Effects of in vivo administration of anti-B7-1/B7-2 monoclonal antibodies on the survival of mice with chronic ongoing myocarditis caused by Coxsackievirus B3.
The Journal of pathology 1999;188(1):107-12.
1999: Suzuki Y; Ra C; Saito K; Horikoshi S; Hasegawa S; Tsuge T; Okumura K; Tomino Y
Expression and physical association of Fc alpha receptor and Fc receptor gamma chain in human mesangial cells.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1999;14(5):1117-23.
1999: Kayagaki N; Yamaguchi N; Nakayama M; Eto H; Okumura K; Yagita H
Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs.
The Journal of experimental medicine 1999;189(9):1451-60.
1999: Hattori K; Hirano T; Miyajima H; Yamakawa N; Ikeda S; Yoshino K; Tateno M; Oshimi K; Kayagaki N; Yagita H; Okumura K
A metalloproteinase inhibitor prevents acute graft-versus-host disease while preserving the graft-versus-leukaemia effect of allogeneic bone marrow transplantation.
British journal of haematology 1999;105(1):303-12.
1999: Kodama T; Takeda K; Shimozato O; Hayakawa Y; Atsuta M; Kobayashi K; Ito M; Yagita H; Okumura K
Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12.
European journal of immunology 1999;29(4):1390-6.
1999: Tsukada N; Kobata T; Aizawa Y; Yagita H; Okumura K
Graft-versus-leukemia effect and graft-versus-host disease can be differentiated by cytotoxic mechanisms in a murine model of allogeneic bone marrow transplantation.
Blood 1999;93(8):2738-47.
1999: Hasegawa S; Pawankar R; Suzuki K; Nakahata T; Furukawa S; Okumura K; Ra C
Functional expression of the high affinity receptor for IgE (FcepsilonRI) in human platelets and its' intracellular expression in human megakaryocytes.
Blood 1999;93(8):2543-51.
1999: Takada T; Kato K; Yagita H; Hamada H; Okumura K
Effects of immunization with tumor cells double transfected with interleukin-2 (IL-2) and interleukin-12 (IL-12) genes on artificial metastasis of colon26 cells in BALB/c mice.
Clinical & experimental metastasis 1999;17(2):125-30.
1999: Ohtsuka Y; Naito K; Yamashiro Y; Yabuta K; Okumura K; Ra C
Induction of anaphylaxis in mouse intestine by orally administered antigen and its prevention with soluble high affinity receptor for IgE.
Pediatric research 1999;45(3):300-5.
1999: Shimozato O; Takeda K; Yagita H; Okumura K
Expression of CD30 ligand (CD153) on murine activated T cells.
Biochemical and biophysical research communications 1999;256(3):519-26.
1999: Kayagaki N; Yamaguchi N; Nakayama M; Kawasaki A; Akiba H; Okumura K; Yagita H
Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(5):2639-47.
1999: Kawahara T; Yagita H; Okumura K; Futagawa S
T cell-mediated effector mechanisms in the rejection of allogeneically transplanted hepatocytes.
Transplantation proceedings 1999;31(1-2):830-1.
1999: Hiraoka S; Furumoto Y; Koseki H; Takagaki Y; Taniguchi M; Okumura K; Ra C
Fc receptor beta subunit is required for full activation of mast cells through Fc receptor engagement.
International immunology 1999;11(2):199-207.
1999: Takahashi N; Seko Y; Azuma M; Yagita H; Okumura K; Yazaki Y
Evidence of cell-mediated cardiac myocyte injury involved in the heart failure of a patient with progressive systemic sclerosis.
Japanese circulation journal 1999;63(1):68-72.
1999: Atsuta R; Akiyama K; Shirasawa T; Okumura K; Fukuchi Y; Ra C
Atopic asthma is dominant in elderly onset asthmatics: possibility for an alteration of mast cell function by aging through Fc receptor expression.
International archives of allergy and immunology 1999;120 Suppl 1():76-81.
1998: Yokoi H; Seki M; Okazoe S; Okumura K; Ichikawa G
[The role and expression of CD27/CD70 in tonsil]
Nippon Jibiinkoka Gakkai kaiho 1998;101(12):1423-9.
1998: Kobayashi S; Goto S; Lord R; Chiba S; Vari F; Okumura K; Nagaoka I
Cytokine expression in hepatocytes of allografted rat livers.
Transplantation proceedings 1998;30(7):2982-3.
1998: Ohtsuka Y; Suzuki R; Nagata S; Oguchi S; Shimizu T; Yamashiro Y; Okumura K; Ra C
Chronic oral antigen exposure induces lymphocyte migration in anaphylactic mouse intestine.
Pediatric research 1998;44(5):791-7.
1998: Seino K; Iwabuchi K; Kayagaki N; Miyata R; Nagaoka I; Matsuzawa A; Fukao K; Yagita H; Okumura K
Chemotactic activity of soluble Fas ligand against phagocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4484-8.
1998: Akiba H; Atsuta M; Yagita H; Okumura K
Identification of rat OX40 ligand by molecular cloning.
Biochemical and biophysical research communications 1998;251(1):131-6.
1998: Suzuki Y; Shirato I; Okumura K; Ravetch J V; Takai T; Tomino Y; Ra C
Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis.
Kidney international 1998;54(4):1166-74.
1998: Kawahara T; Yagita H; Kasai S; Sawa M; Kato K; Okumura K; Futagawa S; Mito M
Allogeneic hepatocyte transplantation: contribution of Fas-Fas ligand interaction to allogeneic hepatocyte rejection.
Journal of gastroenterology and hepatology 1998;13 Suppl():S119-23.
1998: Seko Y; Takahashi N; Azuma M; Yagita H; Okumura K; Yazaki Y
Expression of costimulatory molecule CD40 in murine heart with acute myocarditis and reduction of inflammation by treatment with anti-CD40L/B7-1 monoclonal antibodies.
Circulation research 1998;83(4):463-9.
1998: Nakajima A; Kodama T; Morimoto S; Azuma M; Takeda K; Oshima H; Yoshino S; Yagita H; Okumura K
Antitumor effect of CD40 ligand: elicitation of local and systemic antitumor responses by IL-12 and B7.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1901-7.
1998: Xu M; Miura Y; Nagao F; Muto T; Okumura K
[NK cell activity and subsets of truck drivers along with related factors]
Nippon eiseigaku zasshi. Japanese journal of hygiene 1998;53(2):456-62.
1998: Sekine C; Yagita H; Miyasaka N; Okumura K
Expression and function of CD40 in rheumatoid arthritis synovium.
The Journal of rheumatology 1998;25(6):1048-53.
1998: Hattori K; Hirano T; Miyajima H; Yamakawa N; Tateno M; Oshimi K; Kayagaki N; Yagita H; Okumura K
Differential effects of anti-Fas ligand and anti-tumor necrosis factor alpha antibodies on acute graft-versus-host disease pathologies.
Blood 1998;91(11):4051-5.
1998: Akiba H; Nakano H; Nishinaka S; Shindo M; Kobata T; Atsuta M; Morimoto C; Ware C F; Malinin N L; Wallach D; Yagita H; Okumura K
CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase.
The Journal of biological chemistry 1998;273(21):13353-8.
1998: Ohtsuka Y; Udaka K; Yamashiro Y; Yagita H; Okumura K
Dystrophin acts as a transplantation rejection antigen in dystrophin-deficient mice: implication for gene therapy.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4635-40.
1998: Saito K; Sakurai J; Ohata J; Kohsaka T; Hashimoto H; Okumura K; Abe R; Azuma M
Involvement of CD40 ligand-CD40 and CTLA4-B7 pathways in murine acute graft-versus-host disease induced by allogeneic T cells lacking CD28.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4225-31.
1998: Suzuki K; Hirose T; Matsuda H; Hasegawa S; Okumura K; Ra C
The Fc receptor (FcR) gamma subunit is essential for IgE-binding activity of cell-surface expressed chimeric receptor molecules constructed from human high-affinity IgE receptor (Fc epsilon RI) alpha and FcR gamma subunits.
Molecular immunology 1998;35(5):259-70.
1998: Oshima H; Nakano H; Nohara C; Kobata T; Nakajima A; Jenkins N A; Gilbert D J; Copeland N G; Muto T; Yagita H; Okumura K
Characterization of murine CD70 by molecular cloning and mAb.
International immunology 1998;10(4):517-26.
1998: Mogi S; Ebata T; Setoguchi Y; Fujime M; Heike Y; Kohsaka T; Yagita H; Okumura K; Azuma M
Efficient generation of autologous peripheral blood-derived cytotoxic T lymphocytes against poorly immunogenic human tumors using recombinant CD80-adenovirus together with interleukin 12 and interleukin 2.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(3):713-20.
1998: Seko Y; Takahashi N; Azuma M; Yagita H; Okumura K; Yazaki Y
Effects of in vivo administration of anti-B7-1/B7-2 monoclonal antibodies on murine acute myocarditis caused by coxsackievirus B3.
Circulation research 1998;82(5):613-8.
1998: Nakano H; Shindo M; Sakon S; Nishinaka S; Mihara M; Yagita H; Okumura K
Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3537-42.
1998: Shindo M; Nakano H; Kuroyanagi H; Shirasawa T; Mihara M; Gilbert D J; Jenkins N A; Copeland N G; Yagita H; Okumura K
cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2.
Biochemical and biophysical research communications 1998;244(1):285-92.
1998: Seko Y; Takahashi N; Ishiyama S; Nishikawa T; Kasajima T; Hiroe M; Suzuki S; Ishiwata S; Kawai S; Azuma M; Yagita H; Okumura K; Yazaki Y
Expression of costimulatory molecules B7-1, B7-2, and CD40 in the heart of patients with acute myocarditis and dilated cardiomyopathy.
Circulation 1998;97(7):637-9.
1998: Shindo M; Nakano H; Sakon S; Yagita H; Mihara M; Okumura K
Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization.
Cytogenetics and cell genetics 1998;82(1-2):32-3.
1997: Seko Y; Sato O; Takagi A; Tada Y; Matsuo H; Yagita H; Okumura K; Yazaki Y
Perforin-secreting killer cell infiltration in the aortic tissue of patients with atherosclerotic aortic aneurysm.
Japanese circulation journal 1997;61(12):965-70.
1997: Seino K; Kayagaki N; Tsukada N; Fukao K; Yagita H; Okumura K
Transplantation of CD95 ligand-expressing grafts: influence of transplantation site and difficulty in protecting allo- and xenografts.
Transplantation 1997;64(7):1050-4.
1997: Yamaji C; Hirano T; Miyajima H; Hashimoto H; Okumura K; Ovary Z
Anti-Thy-1 antibody provokes reverse passive cutaneous anaphylaxis-like reactions.
International archives of allergy and immunology 1997;114(2):161-6.
1997: Kawahara T; Kasai S; Yagita H; Sawa M; Kato K; Azuma M; Nakajima A; Okumura K; Futagawa S; Mito M
Critical role of Fas/Fas ligand interaction in CD28-independent pathway of allogeneic murine hepatocyte rejection.
Hepatology (Baltimore, Md.) 1997;26(4):944-8.
1997: Seino K; Kayagaki N; Takeda K; Fukao K; Okumura K; Yagita H
Contribution of Fas ligand to T cell-mediated hepatic injury in mice.
Gastroenterology 1997;113(4):1315-22.
1997: Seko Y; Takahashi N; Yagita H; Okumura K; Yazaki Y
Expression of cytokine mRNAs in murine hearts with acute myocarditis caused by coxsackievirus b3.
The Journal of pathology 1997;183(1):105-8.
1997: Hirano N; Takahashi T; Takahashi T; Azuma M; Okumura K; Yazaki Y; Yagita H; Hirai H
Protective and therapeutic immunity against leukemia induced by irradiated B7-1 (CD80)-transduced leukemic cells.
Human gene therapy 1997;8(11):1375-84.
1997: Maeda K; Sato T; Azuma M; Yagita H; Okumura K
Characterization of rat CD80 and CD86 by molecular cloning and mAb.
International immunology 1997;9(7):993-1000.
1997: Hattori K; Hirano T; Ushiyama C; Miyajima H; Yamakawa N; Ebata T; Wada Y; Ikeda S; Yoshino K; Tateno M; Oshimi K; Kayagaki N; Yagita H; Okumura K
A metalloproteinase inhibitor prevents lethal acute graft-versus-host disease in mice.
Blood 1997;90(2):542-8.
1997: Kaneko H; Hishikawa T; Sekigawa I; Hashimoto H; Okumura K; Kaneko Y
Role of tumour necrosis factor-alpha (TNF-alpha) in the induction of HIV-1 gp120-mediated CD4+ T cell anergy.
Clinical and experimental immunology 1997;109(1):41-6.
1997: Enomoto A; Kato K; Yagita H; Okumura K
Adoptive transfer of cytotoxic T lymphocytes induced by CD86-transfected tumor cells suppresses multi-organ metastases of C1300 neuroblastoma in mice.
Cancer immunology, immunotherapy : CII 1997;44(4):204-10.
1997: Kawahara T; Kasai S; Yagita H; Kato K; Sawa M; Nakajima A; Azuma M; Okumura K; Futagawa S; Mito M
Involvement of Fas and Fas ligand interaction in allogeneic hepatocyte rejection in the spleen.
Transplantation proceedings 1997;29(4):2187-8.
1997: Nozawa K; Kayagaki N; Tokano Y; Yagita H; Okumura K; Hasimoto H
Soluble Fas (APO-1, CD95) and soluble Fas ligand in rheumatic diseases.
Arthritis and rheumatism 1997;40(6):1126-9.
1997: Nakajima A; Watanabe N; Yoshino S; Yagita H; Okumura K; Azuma M
Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells.
International immunology 1997;9(5):637-44.
1997: Nakano H; Shindo M; Yamada K; Yoshida M C; Santee S M; Ware C F; Jenkins N A; Gilbert D J; Yagita H; Copeland N C; Okumura K
Human TNF receptor-associated factor 5 (TRAF5): cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32.
Genomics 1997;42(1):26-32.
1997: Kato K; Okumura K; Yagita H
Immunoregulation by B7 and IL-12 gene transfer.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11 Suppl 3():572-6.
1997: Pawankar R; Okuda M; Yssel H; Okumura K; Ra C
Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells.
The Journal of clinical investigation 1997;99(7):1492-9.
1997: Kayagaki N; Yamaguchi N; Nagao F; Matsuo S; Maeda H; Okumura K; Yagita H
Polymorphism of murine Fas ligand that affects the biological activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3914-9.
1997: Nagao F; Yabe T; Lin L; Tokunaga K; Juji T; Okumura K
Japanese population does not manifest significant association between low NK activity and HLA-B(C) locus homozygosity.
Human immunology 1997;53(1):17-22.
1997: Sagara H; Matsuda H; Wada N; Yagita H; Fukuda T; Okumura K; Makino S; Ra C
A monoclonal antibody against very late activation antigen-4 inhibits eosinophil accumulation and late asthmatic response in a guinea pig model of asthma.
International archives of allergy and immunology 1997;112(3):287-94.
1997: Tsuzuki Y; Miura S; Kurose I; Suematsu M; Higuchi H; Shigematsu T; Kimura H; Serizawa H; Hokari R; Akiba Y; Yagita H; Okumura K; Tso P; Granger D N; Ishii H
Enhanced lymphocyte interaction in postcapillary venules of Peyer's patches during fat absorption in rats.
Gastroenterology 1997;112(3):813-25.
1997: Seino K; Kayagaki N; Fukao K; Okumura K; Yagita H
Rejection of Fas ligand-expressing grafts.
Transplantation proceedings 1997;29(1-2):1092-3.
1997: Kato T; Morokata T; Igarashi O; Yee S T; Inobe M; Uede T; Azuma M; Okumura K; Nariuchi H
Costimulatory effect of IL-12 on the activation of naive, memory CD4+ T cells, and Th1 clone.
Cellular immunology 1997;176(1):50-8.
1997: Tokano Y; Endo S; Hayashi F; Harada S; Kobayashi S; Tsuda H; Takasaki Y; Kyogoku Y; Arata Y; Okumura K; Hashimoto H; Hirose S
A hidden immunoglobulin G2 in patients with rheumatoid arthritis detected by nuclear magnetic resonance.
The Journal of rheumatology 1997;24(2):275-81.
1997: Seino K; Kayagaki N; Okumura K; Yagita H
Antitumor effect of locally produced CD95 ligand.
Nature medicine 1997;3(2):165-70.
1997: Nakajima A; Hirose S; Yagita H; Okumura K
Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1466-72.
1997: Bashuda H; Seino K; Ra C; Yagita H; Okumura K
Lack of cognate help by CD4+ T cells and anergy of CD8+ T cells are the principal mechanisms for anti-leukocyte function-associated antigen-1/intercellular adhesion molecule-1-induced cardiac allograft tolerance.
Transplantation 1997;63(1):113-8.
1997: Aizawa S; Nakano H; Ishida T; Horie R; Nagai M; Ito K; Yagita H; Okumura K; Inoue J; Watanabe T
Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation.
The Journal of biological chemistry 1997;272(4):2042-5.
1997: Tokano Y; Morimoto S; Hishikawa T; Murashima A; Abe M; Sekigawa I; Takasaki Y; Hashimoto H; Okumura K; Shirai T; Hirose S
Subsets of activated T cells in patients with systemic lupus erythematosus: the relation to cell cycle.
Scandinavian journal of rheumatology 1997;26(1):37-42.

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