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Andrew Olaharski

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Andrew J Olaharski; Silvio Albertini; Lutz Mueller; Andreas Zeller; Melanie Struwe; Elmar Gocke; Kyle Kolaja
GADD45α induction in the GreenScreen HC indicator assay does not occur independently of cytotoxicity.
Andrew J Olaharski; Hans Bitter; Nina Gonzaludo; Rama Kondru; David M Goldstein; Tanja S Zabka; Henry Lin; Thomas Singer; Kyle Kolaja
Modeling bone marrow toxicity using kinase structural motifs and the inhibition profiles of small molecular kinase inhibitors.
Andrew J Olaharski; Hirdesh Uppal; Matthew Cooper; Stefan Platz; Tanja S Zabka; Kyle L Kolaja
In vitro to in vivo concordance of a high throughput assay of bone marrow toxicity across a diverse set of drug candidates.

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All Publications

2011: Andrew J Olaharski; Silvio Albertini; Lutz Mueller; Andreas Zeller; Melanie Struwe; Elmar Gocke; Kyle Kolaja
GADD45α induction in the GreenScreen HC indicator assay does not occur independently of cytotoxicity.
Environmental and molecular mutagenesis 2011;52(1):28-34.
2010: Andrew J Olaharski; Hans Bitter; Nina Gonzaludo; Rama Kondru; David M Goldstein; Tanja S Zabka; Henry Lin; Thomas Singer; Kyle Kolaja
Modeling bone marrow toxicity using kinase structural motifs and the inhibition profiles of small molecular kinase inhibitors.
Toxicological sciences : an official journal of the Society of Toxicology 2010;118(1):266-75.
2009: Andrew J Olaharski; Hirdesh Uppal; Matthew Cooper; Stefan Platz; Tanja S Zabka; Kyle L Kolaja
In vitro to in vivo concordance of a high throughput assay of bone marrow toxicity across a diverse set of drug candidates.
Toxicology letters 2009;188(2):98-103.
2009: Andrew J Olaharski; Nina Gonzaludo; Hans Bitter; David Goldstein; Stephan Kirchner; Hirdesh Uppal; Kyle Kolaja
Identification of a kinase profile that predicts chromosome damage induced by small molecule kinase inhibitors.
PLoS computational biology 2009;5(7):e1000446.
2006: Andrew J Olaharski; Zhiying Ji; Ji-Young Woo; Sophia Lim; Alan E Hubbard; Luoping Zhang; Martyn T Smith
The histone deacetylase inhibitor trichostatin a has genotoxic effects in human lymphoblasts in vitro.
Toxicological sciences : an official journal of the Society of Toxicology 2006;93(2):341-7.
2006: Andrew J Olaharski; Rita Sotelo; Gilberto Solorza-Luna; María E Gonsebatt; Patricia Guzman; Alejandro Mohar; David A Eastmond
Tetraploidy and chromosomal instability are early events during cervical carcinogenesis.
Carcinogenesis 2006;27(2):337-43.
2005: Andrew J Olaharski; Jasper Rine; Brett L Marshall; Joshua Babiarz; Luoping Zhang; Eric Verdin; Martyn T Smith
The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases.
PLoS genetics 2005;1(6):e77.
2005: Andrew J Olaharski; S T Mondrala; David A Eastmond
Chromosomal malsegregation and micronucleus induction in vitro by the DNA topoisomerase II inhibitor fisetin.
Mutation research 2005;582(1-2):79-86.
2004: Andrew J Olaharski; David A Eastmond
Elevated levels of tetraploid cervical cells in human papillomavirus-positive Papanicolaou smears diagnosed as atypical squamous cells of undetermined significance.
Cancer 2004;102(3):192-9.