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Olle Olerup

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Physiology

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Disorders

Multiple Sclerosis

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T-Lymphocytes

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Johan Grunewald; Anders Eklund; Olle Olerup
Human leukocyte antigen class I alleles and the disease course in sarcoidosis patients.
Olle Ringdén; Marie Schaffer; Katarina Le Blanc; Ulla Persson; Dan Hauzenberger; Mohammad R Abedi; Olle Olerup; Per Ljungman; Mats Remberger
Which donor should be chosen for hematopoietic stem cell transplantation among unrelated HLA-A, -B, and -DRB1 genomically identical volunteers?
Marie Schaffer; A Aldener-Cannavá; Mats Remberger; Olle Ringdén; Olle Olerup
Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation.

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All Publications

2004: Johan Grunewald; Anders Eklund; Olle Olerup
Human leukocyte antigen class I alleles and the disease course in sarcoidosis patients.
American journal of respiratory and critical care medicine 2004;169(6):696-702.
2004: Olle Ringdén; Marie Schaffer; Katarina Le Blanc; Ulla Persson; Dan Hauzenberger; Mohammad R Abedi; Olle Olerup; Per Ljungman; Mats Remberger
Which donor should be chosen for hematopoietic stem cell transplantation among unrelated HLA-A, -B, and -DRB1 genomically identical volunteers?
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(2):128-34.
2003: Marie Schaffer; A Aldener-Cannavá; Mats Remberger; Olle Ringdén; Olle Olerup
Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation.
Tissue antigens 2003;62(3):243-50.
2003: Cecilia Bernstrand; Henrik Carstensen; Bodil Jakobsen; Arne Svejgaard; Jan-Inge Henter; Olle Olerup
Immunogenetic heterogeneity in single-system and multisystem langerhans cell histiocytosis.
Pediatric research 2003;54(1):30-6.
2002: Johan Grunewald; Jan Wahlström; M Berlin; Hans Wigzell; Anders Eklund; Olle Olerup
Lung restricted T cell receptor AV2S3+ CD4+ T cell expansions in sarcoidosis patients with a shared HLA-DRbeta chain conformation.
Thorax 2002;57(4):348-52.
2001: Marie Schaffer; Olle Olerup
HLA-AB typing by polymerase-chain reaction with sequence-specific primers: more accurate, less errors, and increased resolution compared to serological typing.
Tissue antigens 2001;58(5):299-307.
2001: Kirsten Muri Boberg; Anne Spurkland; Giuseppe Rocca; Thore Egeland; Susanne Saarinen; Stephen Mitchell; Ulrika Broomé; Roger Chapman; Olle Olerup; Albert Pares; Floriano Rosina; Erik Schrumpf
The HLA-DR3,DQ2 heterozygous genotype is associated with an accelerated progression of primary sclerosing cholangitis.
Scandinavian journal of gastroenterology 2001;36(8):886-90.
2001: A Aldener-Cannavá; Olle Olerup
HLA-DPB1 typing by polymerase chain reaction amplification with sequence-specific primers.
Tissue antigens 2001;57(4):287-99.
2001: Jan Wahlström; Kianoosh Katchar; Hans Wigzell; Olle Olerup; Anders Eklund; Johan Grunewald
Analysis of intracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis.
American journal of respiratory and critical care medicine 2001;163(1):115-21.
2000: Susanne Saarinen; Olle Olerup; Ulrika Broomé
Increased frequency of autoimmune diseases in patients with primary sclerosing cholangitis.
The American journal of gastroenterology 2000;95(11):3195-9.
2000: Thomas Masterman; Arturs Ligers; Tomas Olsson; M Andersson; Olle Olerup; Jan Hillert
HLA-DR15 is associated with lower age at onset in multiple sclerosis.
Annals of neurology 2000;48(2):211-9.
2000: Johan Grunewald; M Berlin; Olle Olerup; Anders Eklund
Lung T-helper cells expressing T-cell receptor AV2S3 associate with clinical features of pulmonary sarcoidosis.
American journal of respiratory and critical care medicine 2000;161(3 Pt 1):814-8.
2000: Anna Fogdell-Hahn; Arturs Ligers; M Grønning; Jan Hillert; Olle Olerup
Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease.
Tissue antigens 2000;55(2):140-8.
1999: T Masterma; Arturs Ligers; Olle Olerup; Magnus Vrethem; Jan Hillert
CTLA-4 dimorphisms in gammopathy-associated peripheral neuropathy.
European journal of neurology : the official journal of the European Federation of Neurological Societies 1999;6(4):491-3.
1999: Arturs Ligers; C Xu; Susanne Saarinen; Jan Hillert; Olle Olerup
The CTLA-4 gene is associated with multiple sclerosis.
Journal of neuroimmunology 1999;97(1-2):182-90.
1999: Anne Spurkland; Susanne Saarinen; Kirsten Muri Boberg; Stephen Mitchell; U Broome; Llorenc Caballeria; E Ciusani; Roger Chapman; G Ercilla; O Fausa; I Knutsen; Albert Pares; Floriano Rosina; Olle Olerup; Erik Thorsby; Erik Schrumpf
HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations.
Tissue antigens 1999;53(5):459-69.
1998: Olle Ringdén; Mats Remberger; S Carlens; H Hagglund; Jonas Mattsson; Johan Aschan; B Lönnqvist; S Klaesson; Jacek Winiarski; Tina Dalianis; Olle Olerup; Elda Sparrelid; A Elmhorn-Rosenborg; Britt-Marie Svahn; Per Ljungman
Low incidence of acute graft-versus-host disease, using unrelated HLA-A-, HLA-B-, and HLA-DR-compatible donors and conditioning, including anti-T-cell antibodies.
Transplantation 1998;66(5):620-5.
1997: M Berlin; Anna Fogdell-Hahn; Olle Olerup; Anders Eklund; Johan Grunewald
HLA-DR predicts the prognosis in Scandinavian patients with pulmonary sarcoidosis.
American journal of respiratory and critical care medicine 1997;156(5):1601-5.
1997: Arturs Ligers; Bing He; Anna Fogdell-Hahn; Olle Olerup; Jan Hillert
No linkage or association of a VNTR marker in the junction region of the immunoglobulin heavy chain genes in multiple sclerosis.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1997;24(4):259-64.
1997: H Zetterquist; M Bengtsson; G Bäckström; I Egle-Jansson; A M Ekdahl; N Grunnet; Ida Gustafsson; I Knutsen; A Kuhle; L Rydberg; Anne Spurkland; Rudi Steffensen; M Storgärds; E Szojmer; G Söderholm; B Thuresson; H Turesson; Olle Olerup
Report from the HLA class II typing by PCR-SSP Multicentre Study.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1997;24(3):191-9.
1997: Marita Troye-Blomberg; A Fogdell; G el-Ghazali; A Larsson; M H King; F Sisay-Joof; Olle Olerup; Johan Grunewald; Annette Jepson
Analysis of the T-cell receptor V beta usage in monozygotic and dizygotic twins living in a Plasmodium falciparum endemic area in west Africa.
Scandinavian journal of immunology 1997;45(5):541-5.
1997: Jan Wahlström; M Berlin; R Lundgren; Olle Olerup; Hans Wigzell; Anders Eklund; Johan Grunewald
Lung and blood T-cell receptor repertoire in extrinsic allergic alveolitis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(4):772-9.
1997: Olle Olerup; A Aldener-Cannavá; Anna Fogdell-Hahn; R R Getty; Dawn R Wagenknecht; John A McIntyre
DQB1*0202 and the new DQB1*0203 allele: a fourth pair of DQB1 alleles differing only at codon 57.
Tissue antigens 1997;49(3 Pt 1):271-3.
1997: Ulrika Broomé; Johan Grunewald; A Scheynius; Olle Olerup; Rolf Hultcrantz
Preferential V beta3 usage by hepatic T lymphocytes in patients with primary sclerosing cholangitis.
Journal of hepatology 1997;26(3):527-34.
1997: A Fogdell; Olle Olerup; Sten Fredrikson; Magnus Vrethem; Jan Hillert
Linkage analysis of HLA class II genes in Swedish multiplex families with multiple sclerosis.
Neurology 1997;48(3):758-62.
1997: Marie Schaffer; Olle Olerup
A novel DRB1*13 allele (DRB1*1327) on a DR17, DQ2 haplotype with a DRB1*0301 sequence motif in the 2nd hyperpolymorphic region.
Tissue antigens 1997;49(2):186-8.
1996: Jan Hillert; T Käll; Olle Olerup; Mats Söderström
Distribution of HLA-Dw2 in optic neuritis and multiple sclerosis indicates heterogeneity.
Acta neurologica Scandinavica 1996;94(3):161-6.
1996: A Aldener-Cannavá; Olle Olerup
HLA-DPA1 typing by PCR amplification with sequence-specific primers (PCR-SSP) and distribution of DPA1 alleles in Caucasian, African and Oriental populations.
Tissue antigens 1996;48(3):153-60.
1996: Lennart Emtestam; Olle Olerup
On T-cell recognition of nickel as a hapten.
Acta dermato-venereologica 1996;76(5):344-7.
1996: Lennart Emtestam; P Wallberg; A Aldener; Olle Olerup
Multiple basal cell carcinomas: no association with HLA-DRB, HLA-DQA1 or HLA-DQB1 in Swedish patients.
The British journal of dermatology 1996;134(5):886-91.
1995: H Zetterquist; Olle Olerup
A novel DRB1 allele (HLA-DRB1*1318) featuring a DR8-associated sequence motif on a DR52 haplotype.
Tissue antigens 1995;46(4):337-9.
1995: A Fogdell; Jan Hillert; C Sachs; Olle Olerup
The multiple sclerosis- and narcolepsy-associated HLA class II haplotype includes the DRB5*0101 allele.
Tissue antigens 1995;46(4):333-6.
1995: Olle Olerup; R Olsson; R Hultcrantz; U Broome
HLA-DR and HLA-DQ are not markers for rapid disease progression in primary sclerosing cholangitis.
Gastroenterology 1995;108(3):870-8.
1994: A Aldener-Cannavá; Olle Olerup
HLA-DOB1 "low-resolution' typing by PCR amplification with sequence-specific primers (PCR-SSP).
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1994;21(6):447-55.
1994: Marita Troye-Blomberg; Olle Olerup; Hedvig Perlmann; A Larsson; Gehad Elghazali; A Fogdell; A Jepsen; J P Lepers; J P Pandey; J Grunewald
Characterization of regulatory T-cell responses in humans induced by the P. Falciparum blood stage antigen Pf155/RESA.
Behring Institute Mitteilungen 1994;(95):97-105.
1994: Marita Troye-Blomberg; J P Lepers; K Sjöberg; L Rahalimalala; A Larsson; Olle Olerup; Peter Perlmann
Presentation of the Plasmodium falciparum antigen Pf155/RESA to human T cells. Variations in responsiveness induced by antigen presenting cells from different but MHC class II identical donors.
Immunology letters 1994;43(1-2):59-66.
1994: Olle Olerup; T Daniels; L A Baxter-Lowe
Correct sequence of the A*3001 allele obtained by PCR-SSP typing and automated nucleotide sequencing.
Tissue antigens 1994;44(4):265-7.
1994: A Fogdell; Olle Olerup
The DQA1*0104 allele is carried by DRB1*1001- and DRB1*1401-positive haplotypes in Caucasians, Africans and Orientals.
Tissue antigens 1994;44(1):19-24.
1994: Olle Olerup
Retrospective analysis of HLA-DR typing by serology, TaqI RFLP analysis, and PCR amplification with sequence-specific primers.
Transplantation proceedings 1994;26(3):1750-1.
1994: A Fogdell; Olle Olerup
A novel DRB1 allele (DRB1*1415) formed by interallelic crossing over between the DRB1*1404 and the DRB1*0802 or 0804 alleles.
Tissue antigens 1994;43(5):327-9.
1994: Olle Olerup
HLA-B27 typing by a group-specific PCR amplification.
Tissue antigens 1994;43(4):253-6.
1994: C I Edvard Smith; K B Islam; Igor Vorechovský; Olle Olerup; E Wallin; H Rabbani; B Baskin; Lennart Hammarström
X-linked agammaglobulinemia and other immunoglobulin deficiencies.
Immunological reviews 1994;138():159-83.
1994: Jan Hillert; T Käll; Magnus Vrethem; Sten Fredrikson; M Ohlson; Olle Olerup
The HLA-Dw2 haplotype segregates closely with multiple sclerosis in multiplex families.
Journal of neuroimmunology 1994;50(1):95-100.
1994: Eleanor M Riley; Steve Bennett; Annette Jepson; M Hassan-King; H Whittle; Olle Olerup; Richard Carter
Human antibody responses to Pfs 230, a sexual stage-specific surface antigen of Plasmodium falciparum: non-responsiveness is a stable phenotype but does not appear to be genetically regulated.
Parasite immunology 1994;16(2):55-62.
1993: A Aldener; Olle Olerup
Characterization of a novel DQB1 (DQB1*0609) allele by PCR amplification with sequence-specific primers (PCR-SSP) and nucleotide sequencing.
Tissue antigens 1993;42(5):536-8.
1993: M S Hassan; Olle Olerup; C I Edvard Smith; Lennart Hammarström
Analysis of genetic variables in selective human IgG3 deficiency.
Tissue antigens 1993;41(5):267-8.
1993: Olle Olerup; A Aldener; A Fogdell
HLA-DQB1 and -DQA1 typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours.
Tissue antigens 1993;41(3):119-34.
1993: Lennart Emtestam; H Zetterquist; Olle Olerup
HLA-DR, -DQ and -DP alleles in nickel, chromium, and/or cobalt-sensitive individuals: genomic analysis based on restriction fragment length polymorphisms.
The Journal of investigative dermatology 1993;100(3):271-4.
1993: Jan Hillert; Olle Olerup
Multiple sclerosis is associated with genes within or close to the HLA-DR-DQ subregion on a normal DR15,DQ6,Dw2 haplotype.
Neurology 1993;43(1):163-8.
1992: Olle Olerup; C I Edvard Smith; J Björkander; Lennart Hammarström
Shared HLA class II-associated genetic susceptibility and resistance, related to the HLA-DQB1 gene, in IgA deficiency and common variable immunodeficiency.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10653-7.
1992: C B Sanjeevi; P R Narayanan; R Prabakar; N Charles; B E Thomas; R Balasubramaniam; Olle Olerup
No association or linkage with HLA-DR or -DQ genes in south Indians with pulmonary tuberculosis.
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1992;73(5):280-4.
1992: C B Sanjeevi; Olle Olerup
Restriction fragment length polymorphism analysis of HLA-DRB, -DQA, and -DQB genes in south Indians and Swedish Caucasians.
Transplantation proceedings 1992;24(5):1687-8.
1992: E Riley; Olle Olerup
HLA polymorphisms and evolution.
Immunology today 1992;13(9):333-5.
1992: H Zetterquist; U Broomé; K Einarsson; Olle Olerup
HLA class II genes in primary sclerosing cholangitis and chronic inflammatory bowel disease: no HLA-DRw52a association in Swedish patients with sclerosing cholangitis.
Gut 1992;33(7):942-6.
1992: Olle Olerup; H Zetterquist
HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation.
Tissue antigens 1992;39(5):225-35.
1992: H Zetterquist; Olle Olerup
Identification of the HLA-DRB1*04, -DRB1*07, and -DRB1*09 alleles by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours.
Human immunology 1992;34(1):64-74.
1992: K Sjöberg; J P Lepers; Lucie A Raharimalala; A Larsson; Olle Olerup; N T Marbiah; Marita Troye-Blomberg; Peter Perlmann
Genetic regulation of human anti-malarial antibodies in twins.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2101-4.
1992: Sten Fredrikson; J Michelsberg; Jan Hillert; Z Wang; Jia-Bin Sun; Olle Olerup; Tomas Olsson; Hans Link
Conjugal multiple sclerosis: immunogenetic characterization and analysis of T- and B-cell reactivity to myelin proteins.
Neurology 1992;42(3 Pt 1):577-82.
1992: C B Sanjeevi; V Seshiah; E Möller; Olle Olerup
Different genetic backgrounds for malnutrition-related diabetes and type 1 (insulin-dependent) diabetes mellitus in south Indians.
Diabetologia 1992;35(3):283-6.
1992: Jan Hillert; Olle Olerup
Germ-line polymorphism of TCR genes and disease susceptibility--fact or hypothesis?
Immunology today 1992;13(2):47-9.
1992: Jan Hillert; C Leng; Olle Olerup
T-cell receptor alpha chain germline gene polymorphisms in multiple sclerosis.
Neurology 1992;42(1):80-4.
1991: J Wallin; Jan Hillert; Olle Olerup; B Carlsson; H Ström
Association of rheumatoid arthritis with a dominant DR1/Dw4/Dw14 sequence motif, but not with T cell receptor beta chain gene alleles or haplotypes.
Arthritis and rheumatism 1991;34(11):1416-24.
1991: Olle Olerup; H Zetterquist; E Möller
[Identification of HLA class II polymorphism with molecular biology techniques].
Läkartidningen 1991;88(40):3275-7.
1991: Marita Troye-Blomberg; Olle Olerup; A Larsson; K Sjöberg; Hedvig Perlmann; E Riley; J P Lepers; Peter Perlmann
Failure to detect MHC class II associations of the human immune response induced by repeated malaria infections to the Plasmodium falciparum antigen Pf155/RESA.
International immunology 1991;3(10):1043-51.
1991: Olle Olerup; M Troye-Blomberg; G M Schreuder; E M Riley
HLA-DR and -DQ gene polymorphism in West Africans is twice as extensive as in north European Caucasians: evolutionary implications.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8480-4.
1991: Olle Olerup; Jan Hillert
HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation.
Tissue antigens 1991;38(1):1-15.
1991: Olle Olerup; H Zetterquist
HLA-DRB1*01 subtyping by allele-specific PCR amplification: a sensitive, specific and rapid technique.
Tissue antigens 1991;37(5):197-204.
1991: Jan Hillert; C Leng; Olle Olerup
No association with germline T cell receptor beta-chain gene alleles or haplotypes in Swedish patients with multiple sclerosis.
Journal of neuroimmunology 1991;32(2):141-7.
1991: Jan Hillert; P O Osterman; Olle Olerup
No association with HLA-DR, -DQ or -DP alleles in Guillain-Barré syndrome.
Journal of neuroimmunology 1991;31(1):67-72.
1990: E Möller; J Böhme; M A Valugerdi; A Ridderstad; Olle Olerup
Speculations on mechanisms of HLA associations with autoimmune diseases and the specificity of "autoreactive" T lymphocytes.
Immunological reviews 1990;118():5-19.
1990: Olle Olerup; E Möller; U Persson
HLA-DP incompatibilities induce significant proliferation in primary mixed lymphocyte cultures in HLA-A, -B, -DR and -DQ compatible individuals: implications for allogeneic bone marrow transplantation.
Tissue antigens 1990;36(5):194-202.
1990: Olle Olerup; Holger Luthman; E Martin Ritzén; B Haglund-Stengler
TaqI HLA-B and -DRB RFLP analysis can predict disease in siblings of affected children with 21-hydroxylase deficiency.
Human genetics 1990;85(5):467-72.
1990: Olle Olerup; C I Edvard Smith; Lennart Hammarström
Different amino acids at position 57 of the HLA-DQ beta chain associated with susceptibility and resistance to IgA deficiency.
Nature 1990;347(6290):289-90.
1990: Olle Olerup
HLA class II typing by digestion of PCR-amplified DNA with allele-specific restriction endonucleases will fail to unequivocally identify the genotypes of many homozygous and heterozygous individuals.
Tissue antigens 1990;36(2):83-7.
1990: Marita Troye-Blomberg; K Sjöberg; Olle Olerup; E M Riley; L Kabilan; Hedvig Perlmann; N T Marbiah; Peter Perlmann
Characterization of regulatory T cell responses to defined immunodominant T cell epitopes of the Plasmodium falciparum antigen Pf155/RESA.
Immunology letters 1990;25(1-3):129-34.
1990: Olle Olerup; Jan Hillert; Sten Fredrikson
The HLA-D region-associated MS-susceptibility genes may be located telomeric to the HLA-DP subregion.
Tissue antigens 1990;36(1):37-9.
1990: Olle Olerup; E Möller; U Persson
HLA-DP incompatibilities induce proliferation in primary mixed lymphocyte culture in HLA-A, -B, -C, -DR, and -DQ-identical individuals.
Transplantation proceedings 1990;22(1):141-2.
1990: Olle Olerup; H Zetterquist; L Ohlson; B Carlsson; J Wallin; E Möller
Genomic HLA-DR and -DQ typing by Taq I RFLP analysis: an alternative to serologic tissue typing.
Transplantation proceedings 1990;22(1):144.
1990: Olle Olerup; M Schaffer; Jan Hillert; C Sachs
The narcolepsy-associated DRw15,DQw6,Dw2 haplotype has no unique HLA-DQA or -DQB restriction fragments and does not extend to the HLA-DP subregion.
Immunogenetics 1990;32(1):41-4.
1989: Olle Olerup; Jan Hillert; Sten Fredrikson; Tomas Olsson; S Kam-Hansen; E Möller; B Carlsson; J Wallin
Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(18):7113-7.
1989: J Wallin; B Carlsson; Olle Olerup; E Möller
Individuals with HLA-DR blank alleles display well-known DR-DQ RFLPs.
Tissue antigens 1989;34(1):9-16.
1988: Marita Troye-Blomberg; L Kabilan; E M Riley; J Ortlund; G Andersson; Hedvig Perlmann; Olle Olerup; B Högh; Eskild Petersen; R W Snow
T cell reactivity of defined peptides from a major Plasmodium falciparum vaccine candidate: the Pf155/RESA antigen.
Immunology letters 1988;19(3):229-33.
1988: E Möller; B Carlsson; Olle Olerup; J Wallin
Polymorphism of HLA class II genes in various diseases.
Annals of the New York Academy of Sciences 1988;546():143-50.
1988: Olle Olerup; Lennart Emtestam
Allergic contact dermatitis to nickel is associated with a Taq I HLA-DQA allelic restriction fragment.
Immunogenetics 1988;28(5):310-3.
1987: Olle Olerup; J Wallin; B Carlsson; J Marcusson; Lennart Emtestam; E Björnelius; E Möller
Genomic HLA-typing by RFLP-analysis using DR beta and DQ beta cDNA probes reveals normal DR-DQ linkages in patients with psoriasis vulgaris.
Tissue antigens 1987;30(3):139-42.
1987: Olle Olerup; B Carlsson; J Wallin; Tomas Olsson; Sten Fredrikson; Jan Ernerudh; E Möller
Genomic HLA-typing by RFLP-analysis using DR beta and DQ beta cDNA probes reveals normal DR-DQ linkages in patients with multiple sclerosis.
Tissue antigens 1987;30(3):135-8.