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Søren-Peter Olesen

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Jens-Peter David; Søren-Peter Olesen; Hanne B Rasmussen; Martin N Andersen; Nicole Schmitt
Trafficking of the IKs -complex in MDCK cells: site of subunit assembly and determinants of polarized localization.
Christel Kroigaard; Olga Kudryavtseva; Søren-Peter Olesen; Thomas Dalsgaard; Christine Wandall-Frostholm; Ulf Simonsen
K(Ca)3.1 channel downregulation and impaired endothelium-derived hyperpolarization-type relaxation in pulmonary arteries from chronically hypoxic rats.
Nina Oyen; Mattis F Ranthe; Jan Wohlfahrt; Heather A Boyd; Lisbeth Carstensen; Morten S Olesen; Søren-Peter Olesen; Mads Melbye
Familial aggregation of lone atrial fibrillation in young persons.

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2013: Jens-Peter David; Søren-Peter Olesen; Hanne B Rasmussen; Martin N Andersen; Nicole Schmitt
Trafficking of the IKs -complex in MDCK cells: site of subunit assembly and determinants of polarized localization.
Traffic (Copenhagen, Denmark) 2013;14(4):399-411.
2013: Christel Kroigaard; Olga Kudryavtseva; Søren-Peter Olesen; Thomas Dalsgaard; Christine Wandall-Frostholm; Ulf Simonsen
K(Ca)3.1 channel downregulation and impaired endothelium-derived hyperpolarization-type relaxation in pulmonary arteries from chronically hypoxic rats.
Experimental physiology 2013;98(4):957-69.
2012: Nina Oyen; Mattis F Ranthe; Jan Wohlfahrt; Heather A Boyd; Lisbeth Carstensen; Morten S Olesen; Søren-Peter Olesen; Mads Melbye
Familial aggregation of lone atrial fibrillation in young persons.
Journal of the American College of Cardiology 2012;60(10):917-21.
2012: Morten S Olesen; Søren-Peter Olesen; Nicole Schmitt; Lei Yuan; Michael Christiansen; Stig Haunsø; Paula L Hedley; Anders G Holst; Thomas Jespersen; Bo Liang; Jonas B Nielsen; Nikolaj Nielsen; Jesper H Svendsen
High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation.
Circulation. Cardiovascular genetics 2012;5(4):450-9.
2012: Jonathan M Cordeiro; José M Di Diego; Dana Giannandrea; Bruce Kornreich; N Sydney Moise; Søren-Peter Olesen; Kirstine Calloe; Charles Antzelevitch
Physiological consequences of transient outward K+ current activation during heart failure in the canine left ventricle.
Journal of molecular and cellular cardiology 2012;52(6):1291-8.
2012: Katarzyna Krzystanek; Søren-Peter Olesen; Hanne Borger Rasmussen; Olivier Staub; Hugues Abriel; Morten Grunnet; Thomas Jespersen
Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels.
Heart rhythm : the official journal of the Heart Rhythm Society 2012;9(3):440-8.
2011: Ewa Soltysinska; Stefanie Thiele; Søren-Peter Olesen; Oleg E Osadchii
Chronic sympathetic activation promotes downregulation of β-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction.
Pflügers Archiv : European journal of physiology 2011;462(4):529-43.
2011: Morten Laursen; Morten Grunnet; Thomas Jespersen; Søren-Peter Olesen; Tomas Mow
Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts.
Journal of pharmacological and toxicological methods 2011;64(2):134-44.
2011: Kirstine Calloe; Natalie Chlus; Charles Antzelevitch; José M Di Diego; Thomas Jespersen; Eyal Nof; Søren-Peter Olesen; Jonathan M Cordeiro
Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes.
Journal of cardiovascular electrophysiology 2011;22(9):1057-66.
2011: Anders Peter Larsen; Morten Grunnet; Annette Buur Steffensen; Søren-Peter Olesen
Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state.
Biophysical journal 2011;101(4):818-27.
2011: Ewa Soltysinska; Søren-Peter Olesen; Oleg E Osadchii
Myocardial structural, contractile and electrophysiological changes in the guinea-pig heart failure model induced by chronic sympathetic activation.
Experimental physiology 2011;96(7):647-63.
2011: Martin N Andersen; Søren-Peter Olesen; Hanne B Rasmussen
Kv7.1 surface expression is regulated by epithelial cell polarization.
American journal of physiology. Cell physiology 2011;300(4):C814-24.
2011: Morten S Olesen; Thomas Jespersen; Jonas B Nielsen; Bo Liang; Daniel V Møller; Paula Hedley; Michael Christiansen; András Varró; Søren-Peter Olesen; Stig Haunsø; Nicole Schmitt; Jesper H Svendsen
Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.
Cardiovascular research 2011;89(4):786-93.
2011: Morten Laursen; Søren-Peter Olesen; Morten Grunnet; Tomas Mow; Thomas Jespersen
Characterization of cardiac repolarization in the Göttingen minipig.
Journal of pharmacological and toxicological methods 2011;63(2):186-95.
2010: A Lundby; Thomas Jespersen; Nicole Schmitt; Morten Grunnet; Søren-Peter Olesen; Jonathan M Cordeiro; Kirstine Calloe
Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.
British journal of pharmacology 2010;160(8):2028-44.
2010: Anders Peter Larsen; Søren-Peter Olesen; Morten Grunnet; Steven Poelzing
Pharmacological activation of IKr impairs conduction in guinea pig hearts.
Journal of cardiovascular electrophysiology 2010;21(8):923-9.
2010: Yanzong Yang; Yiqing Yang; Bo Liang; Jinqiu Liu; Jun Li; Morten Grunnet; Søren-Peter Olesen; Hanne B Rasmussen; Patrick T Ellinor; Lianjun Gao; Xiaoping Lin; Li Li; Lei Wang; Junjie Xiao; Yi Liu; Ying Liu; Shulong Zhang; Dandan Liang; Luying Peng; Thomas Jespersen; Yi-Han Chen
Identification of a Kir3.4 mutation in congenital long QT syndrome.
American journal of human genetics 2010;86(6):872-80.
2010: Jørgen Søndergaard; Poul Erik Mouritzen; Søren-Peter Olesen; Søren Molin; Hans Fink; Frede Blaabjerg; Gunnar Sivertsen
[We wish more professional debate about the bibliometric research indicators].
Ugeskrift for laeger 2010;172(12):984; author reply 984.
2010: Bo Hjorth Bentzen; Rune Wederkinck Andersen; Søren-Peter Olesen; Morten Grunnet; Antonio Nardi
Synthesis and characterisation of NS13558: a new important tool for addressing KCa1.1 channel function ex vivo.
Naunyn-Schmiedeberg's archives of pharmacology 2010;381(3):271-83.
2010: Jeffrey J Layne; Bernhard Nausch; Søren-Peter Olesen; Mark T Nelson
BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;298(2):R378-84.
2010: Anders Peter Larsen; Søren-Peter Olesen
Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics.
PloS one 2010;5(2):e9021.
2010: Kirstine Calloe; Ewa Soltysinska; Thomas Jespersen; Alicia Lundby; Charles Antzelevitch; Søren-Peter Olesen; Jonathan M Cordeiro
Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle.
Journal of molecular and cellular cardiology 2010;48(1):191-200.
2009: Ewa Soltysinska; Søren-Peter Olesen; Torsten Christ; Erich Wettwer; Andras Varró; Morten Grunnet; Thomas Jespersen
Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.
Pflügers Archiv : European journal of physiology 2009;459(1):11-23.
2009: Karoline Einarsen; Kirstine Calloe; Morten Grunnet; Søren-Peter Olesen; Nicole Schmitt
Functional properties of human neuronal Kv11 channels.
Pflügers Archiv : European journal of physiology 2009;458(4):689-700.
2009: Jacob Tfelt-Hansen; Søren-Peter Olesen; Jesper Hastrup Svendsen; Thomas Jespersen
[Inherited cardiac diseases caused by Nav1.5 sodium channel mutations].
Ugeskrift for laeger 2009;171(15):1261-5.
2009: Jacob Tfelt-Hansen; T Jespersen; J Hofman-Bang; H Borger Rasmussen; P Cedergreen; Flemming Skovby; H Abriel; Jesper Hastrup Svendsen; Søren-Peter Olesen; Michael Christiansen; Stig Haunso
Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A.
The Canadian journal of cardiology 2009;25(3):156-60.
2009: Kirstine Calloe; Jonathan M Cordeiro; José M Di Diego; Rie Schultz Hansen; Morten Grunnet; Søren-Peter Olesen; Charles Antzelevitch
A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome.
Cardiovascular research 2009;81(4):686-94.
2009: Bo Hjorth Bentzen; Oleg Osadchii; Thomas Jespersen; Rie Schultz Hansen; Søren-Peter Olesen; Morten Grunnet
Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury.
Pflügers Archiv : European journal of physiology 2009;457(5):979-88.
2008: Christian Frøkjaer-Jensen; M Wayne Davis; Christopher E Hopkins; Blake J Newman; Jason M Thummel; Søren-Peter Olesen; Morten Grunnet; Erik M Jorgensen
Single-copy insertion of transgenes in Caenorhabditis elegans.
Nature genetics 2008;40(11):1375-83.
2008: Johannes P Hofgaard; Kathrin Banach; Sarah Mollerup; Helene Korvenius Jørgensen; Søren-Peter Olesen; Niels-Henrik Holstein-Rathlou; Morten Schak Nielsen
Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes.
Pflügers Archiv : European journal of physiology 2008;457(2):303-13.
2008: Morten Grunnet; Rie Schultz Hansen; Søren-Peter Olesen
hERG1 channel activators: a new anti-arrhythmic principle.
Progress in biophysics and molecular biology 2008;98(2-3):347-62.
2008: Anders Peter Larsen; Søren-Peter Olesen; Morten Grunnet; Thomas Jespersen
Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.
Pflügers Archiv : European journal of physiology 2008;456(6):1137-48.
2008: Rie Schultz Hansen; Søren-Peter Olesen; Lars Christian B Rønn; Morten Grunnet
In vivo effects of the IKr agonist NS3623 on cardiac electrophysiology of the guinea pig.
Journal of cardiovascular pharmacology 2008;52(1):35-41.
2008: Torben Peitersen; Morten Grunnet; Alan P Benson; Arun V Holden; Niels-Henrik Holstein-Rathlou; Søren-Peter Olesen
Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(5):734-41.
2008: Antonio Nardi; Søren-Peter Olesen
BK channel modulators: a comprehensive overview.
Current medicinal chemistry 2008;15(11):1126-46.
2008: Alicia Lundby; Lasse Steen Ravn; Jesper Hastrup Svendsen; Stig Hauns; Søren-Peter Olesen; Nicole Schmitt
KCNE3 mutation V17M identified in a patient with lone atrial fibrillation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008;21(1-3):47-54.
2007: Kirstine Calloe; Lasse Steen Ravn; Nicole Schmitt; jin liang sui; Morten Duno; Stig Haunso; Morten Grunnet; Jesper Hastrup Svendsen; Søren-Peter Olesen
Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.
Biochemical and biophysical research communications 2007;364(4):889-95.
2007: Alicia Lundby; Lasse Steen Ravn; Jesper Hastrup Svendsen; Søren-Peter Olesen; Nicole Schmitt
KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(12):1532-41.
2007: Bo Hjorth Bentzen; Antonio Nardi; Kirstine Calloe; Lars Siim Madsen; Søren-Peter Olesen; Morten Grunnet
The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels.
Molecular pharmacology 2007;72(4):1033-44.
2007: Pernille Elmedyb; Søren-Peter Olesen; Morten Grunnet
Activation of ERG2 potassium channels by the diphenylurea NS1643.
Neuropharmacology 2007;53(2):283-94.
2007: Rie Schultz Hansen; Søren-Peter Olesen; Morten Grunnet
Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart.
The Journal of pharmacology and experimental therapeutics 2007;321(3):996-1002.
2007: Pernille Elmedyb; Kirstine Calloe; Nicole Schmitt; Rie Schultz Hansen; Morten Grunnet; Søren-Peter Olesen
Modulation of ERG channels by XE991.
Basic & clinical pharmacology & toxicology 2007;100(5):316-22.
2007: Henrik Sindal Jensen; Morten Grunnet; Søren-Peter Olesen
Inactivation as a new regulatory mechanism for neuronal Kv7 channels.
Biophysical journal 2007;92(8):2747-56.
2007: Thomas Jespersen; Mathieu Membrez; Céline S Nicolas; Bruno Pitard; Olivier Staub; Søren-Peter Olesen; Isabelle Baro; Hugues Abriel
The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family.
Cardiovascular research 2007;74(1):64-74.
2007: Nathalie H Nielsen; Bo G Winkel; Jørgen K Kanters; Nicole Schmitt; Jacob Hofman-Bang; Henrik Sindal Jensen; Bo Hjorth Bentzen; Bjarne Sigurd; Lars Larsen; Paal Skytt Andersen; Stig Haunsø; Keld Kjeldsen; Morten Grunnet; Michael Christiansen; Søren-Peter Olesen
Mutations in the Kv1.5 channel gene KCNA5 in cardiac arrest patients.
Biochemical and biophysical research communications 2007;354(3):776-82.
2007: Hanne B Rasmussen; Christian Frøkjaer-Jensen; Camilla S Jensen; Henrik Sindal Jensen; Nanna K Jørgensen; Hiroaki Misono; James Trimmer; Søren-Peter Olesen; Nicole Schmitt
Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.
Journal of cell science 2007;120(Pt 6):953-63.
2006: Bo Hjorth Bentzen; Nicole Schmitt; Kirstine Calloe; William Dalby-Brown; Morten Grunnet; Søren-Peter Olesen
The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.
Neuropharmacology 2006;51(6):1068-77.
2006: Rie Schultz Hansen; Thomas Goldin Diness; Torsten Christ; Erich Wettwer; Ursula Ravens; Søren-Peter Olesen; Morten Grunnet
Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N'-(3'-trifluoromethylphenyl)urea].
Molecular pharmacology 2006;70(4):1319-29.
2006: Alicia Lundby; Søren-Peter Olesen
KCNE3 is an inhibitory subunit of the Kv4.3 potassium channel.
Biochemical and biophysical research communications 2006;346(3):958-67.
2006: Thomas Goldin Diness; Rie Schultz Hansen; Søren-Peter Olesen; Morten Grunnet
Frequency-dependent modulation of KCNQ1 and HERG1 potassium channels.
Biochemical and biophysical research communications 2006;343(4):1224-33.
2006: Torben Peitersen; Charlotte Hougaard; Thomas Jespersen; Nanna K Jorgensen; Søren-Peter Olesen; Morten Grunnet
Subtype-specific, bi-component inhibition of SK channels by low internal pH.
Biochemical and biophysical research communications 2006;343(3):943-9.
2006: Thomas Jespersen; Morten Grunnet; Hanne B Rasmussen; Nils B Jørgensen; Henrik Sindal Jensen; Kamilla Angelo; Søren-Peter Olesen; Dan A Klaerke
The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?
Biochemical and biophysical research communications 2006;341(4):979-88.
2006: Oscar Casis; Søren-Peter Olesen; Michael C Sanguinetti
Mechanism of action of a novel human ether-a-go-go-related gene channel activator.
Molecular pharmacology 2006;69(2):658-65.
2006: William Dalby-Brown; Henrik H Hansen; Mads P G Korsgaard; Naheed Mirza; Søren-Peter Olesen
K(v)7 channels: function, pharmacology and channel modulators.
Current topics in medicinal chemistry 2006;6(10):999-1023.
2006: Rie Schultz Hansen; Thomas Goldin Diness; Torsten Christ; Joachim Demnitz; Ursula Ravens; Søren-Peter Olesen; Morten Grunnet
Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).
Molecular pharmacology 2006;69(1):266-77.
2005: Thomas Jespersen; Morten Grunnet; Søren-Peter Olesen
The KCNQ1 potassium channel: from gene to physiological function.
Physiology (Bethesda, Md.) 2005;20():408-16.
2005: Morten Grunnet; Elijah Raphael Behr; Kirstine Calloe; Jacob Hofman-Bang; Jan Till; Michael Christiansen; William John McKenna; Søren-Peter Olesen; Nicole Schmitt
Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome.
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(11):1238-49.
2005: Henrik Sindal Jensen; Kirstine Callø; Thomas Jespersen; Bo Skaaning Jensen; Søren-Peter Olesen
The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.
Brain research. Molecular brain research 2005;139(1):52-62.
2005: Kirstine Calloe; Pernille Elmedyb; Søren-Peter Olesen; Nanna K Jorgensen; Morten Grunnet
Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.
Biophysical journal 2005;89(3):2159-69.
2005: Lars Siim Madsen; palle christophersen; Søren-Peter Olesen
Blockade of Ca2+-activated K+ channels in T cells: an option for the treatment of multiple sclerosis?
European journal of immunology 2005;35(4):1023-6.
2005: Morten Grunnet; Søren-Peter Olesen; Dan A Klaerke; Thomas Jespersen
hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics.
Biochemical and biophysical research communications 2005;328(4):1146-53.
2005: Delphine S Dupuis; Dan A Klaerke; Søren-Peter Olesen
Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels.
Basic & clinical pharmacology & toxicology 2005;96(2):123-30.
2004: Dorte Strøbaek; Lene Teuber; Tino Dyhring; Philip K Ahring; Katrine Kjaer; Rie Schultz Hansen; Søren-Peter Olesen; palle christophersen; Bo Skaaning-Jensen
Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime).
Biochimica et biophysica acta 2004;1665(1-2):1-5.
2004: Thomas Jespersen; Hanne B Rasmussen; Morten Grunnet; Henrik Sindal Jensen; Kamilla Angelo; Delphine S Dupuis; Lotte K Vogel; Nanna K Jorgensen; Dan A Klaerke; Søren-Peter Olesen
Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.
Journal of cell science 2004;117(Pt 19):4517-26.
2004: Hanne B Rasmussen; Morten Møller; Hans-Günther Knaus; Bo Skaaning Jensen; Søren-Peter Olesen; Nanna K Jørgensen
Subcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heart.
American journal of physiology. Heart and circulatory physiology 2004;286(4):H1300-9.
2004: Charlotte Hougaard; Dan A Klaerke; Else Hoffmann; Søren-Peter Olesen; Nanna K Jorgensen
Modulation of KCNQ4 channel activity by changes in cell volume.
Biochimica et biophysica acta 2004;1660(1-2):1-6.
2003: Morten Grunnet; Thomas Jespersen; Eskild Colding-Jørgensen; Marianne Schwartz; Dan A Klaerke; John Vissing; Søren-Peter Olesen; Morten Duno
Characterization of two new dominant ClC-1 channel mutations associated with myotonia.
Muscle & nerve 2003;28(6):722-32.
2003: Kamilla Angelo; Yuliya V Korolkova; Morten Grunnet; Eugene V Grishin; Kirill A Pluzhnikov; Dan A Klaerke; Hans-Günther Knaus; Morten Møller; Søren-Peter Olesen
A radiolabeled peptide ligand of the hERG channel, [125I]-BeKm-1.
Pflügers Archiv : European journal of physiology 2003;447(1):55-63.
2003: Nanna K Jorgensen; Stine F Pedersen; Hanne B Rasmussen; Morten Grunnet; Dan A Klaerke; Søren-Peter Olesen
Cell swelling activates cloned Ca(2+)-activated K(+) channels: a role for the F-actin cytoskeleton.
Biochimica et biophysica acta 2003;1615(1-2):115-25.
2003: Morten Grunnet; Hanne B Rasmussen; Anders Hay-Schmidt; Maiken W Rosenstierne; Dan A Klaerke; Søren-Peter Olesen; Thomas Jespersen
KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.
Biophysical journal 2003;85(3):1525-37.
2003: Trine Ljungstrom; Morten Grunnet; Bo Skaaning Jensen; Søren-Peter Olesen
Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels.
Pflügers Archiv : European journal of physiology 2003;446(6):684-94.
2003: Rikke Louise Schrøder; Dorte Strøbaek; Søren-Peter Olesen; palle christophersen
Voltage-independent KCNQ4 currents induced by (+/-)BMS-204352.
Pflügers Archiv : European journal of physiology 2003;446(5):607-16.
2003: Morten Grunnet; Thomas Jespersen; Nanna MacAulay; Nanna K Jørgensen; Nicole Schmitt; Olaf Pongs; Søren-Peter Olesen; Dan A Klaerke
KCNQ1 channels sense small changes in cell volume.
The Journal of physiology 2003;549(Pt 2):419-27.
2003: Tina C Stummann; Jørgen H Poulsen; Anders Hay-Schmidt; Morten Grunnet; Dan A Klaerke; Hanne B Rasmussen; Søren-Peter Olesen; Nanna K Jorgensen
Pharmacological investigation of the role of ion channels in salivary secretion.
Pflügers Archiv : European journal of physiology 2003;446(1):78-87.
2003: Niels J Willumsen; Morten Bech; Søren-Peter Olesen; Bo Skaaning Jensen; Mads P G Korsgaard; palle christophersen
High throughput electrophysiology: new perspectives for ion channel drug discovery.
Receptors & channels 2003;9(1):3-12.
2002: Yuliya V Korolkova; Eduard V Bocharov; Kamilla Angelo; Innokentiy Maslennikov; Olga V Grinenko; Aleksey V Lipkin; Elena D Nosyreva; Kirill A Pluzhnikov; Søren-Peter Olesen; Alexander S Arseniev; Eugene V Grishin
New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
The Journal of biological chemistry 2002;277(45):43104-9.
2002: Kamilla Angelo; Thomas Jespersen; Morten Grunnet; Morten Schak Nielsen; Dan A Klaerke; Søren-Peter Olesen
KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.
Biophysical journal 2002;83(4):1997-2006.
2002: Ninna R Holm; palle christophersen; jorn hounsgaard; Steen Gammeltoft; Søren-Peter Olesen
CNTF inhibits high voltage activated Ca2+ currents in fetal mouse cortical neurones.
Journal of neurochemistry 2002;82(3):495-503.
2002: Morten Grunnet; Thomas Jespersen; Hanne B Rasmussen; Trine Ljungstrøm; Nanna K Jorgensen; Søren-Peter Olesen; Dan A Klaerke
KCNE4 is an inhibitory subunit to the KCNQ1 channel.
The Journal of physiology 2002;542(Pt 1):119-30.
2002: Morten Grunnet; Nanna MacAulay; Nanna K Jorgensen; Skaaning Jensen; Søren-Peter Olesen; Dan A Klaerke
Regulation of cloned, Ca2+-activated K+ channels by cell volume changes.
Pflügers Archiv : European journal of physiology 2002;444(1-2):167-77.
2002: Thomas Jespersen; Morten Grunnet; Kamilla Angelo; Dan A Klaerke; Søren-Peter Olesen
Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.
BioTechniques 2002;32(3):536-8, 540.
2002: Delphine S Dupuis; Rikke Louise Schrøder; Thomas Jespersen; Jeppe K Christensen; palle christophersen; Bo Skaaning Jensen; Søren-Peter Olesen
Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.
European journal of pharmacology 2002;437(3):129-37.
2001: Bo Skaaning Jensen; Dorte Strøbaek; Søren-Peter Olesen; palle christophersen
The Ca2+-activated K+ channel of intermediate conductance: a molecular target for novel treatments?
Current drug targets 2001;2(4):401-22.
2001: M P Gersdorff Korsgaard; palle christophersen; Philip K Ahring; Søren-Peter Olesen
Identification of a novel voltage-gated Na+ channel rNa(v)1.5a in the rat hippocampal progenitor stem cell line HiB5.
Pflügers Archiv : European journal of physiology 2001;443(1):18-30.
2001: Rikke Louise Schrøder; Thomas Jespersen; palle christophersen; Dorte Strøbaek; Bo Skaaning Jensen; Søren-Peter Olesen
KCNQ4 channel activation by BMS-204352 and retigabine.
Neuropharmacology 2001;40(7):888-98.
2001: Morten Grunnet; Thomas Jespersen; Kamilla Angelo; Christian Frøkjaer-Jensen; Dan A Klaerke; Søren-Peter Olesen; Bo Skaaning Jensen
Pharmacological modulation of SK3 channels.
Neuropharmacology 2001;40(7):879-87.
2001: R Søgaard; Trine Ljungstrøm; KA Pedersen; Søren-Peter Olesen; Bo Skaaning Jensen
KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology.
American journal of physiology. Cell physiology 2001;280(4):C859-66.
2001: Yuliya V Korolkova; Sergey A Kozlov; Aleksey V Lipkin; Kirill A Pluzhnikov; J K Hadley; A K Filippov; D A Brown; Kamilla Angelo; Dorte Strøbaek; Thomas Jespersen; Søren-Peter Olesen; Bo Skaaning Jensen; Eugene V Grishin
An ERG channel inhibitor from the scorpion Buthus eupeus.
The Journal of biological chemistry 2001;276(13):9868-76.
2001: Morten Grunnet; Bo Skaaning Jensen; Søren-Peter Olesen; Dan A Klaerke
Apamin interacts with all subtypes of cloned small-conductance Ca2+-activated K+ channels.
Pflügers Archiv : European journal of physiology 2001;441(4):544-50.
2000: Rikke Louise Schrøder; Bo Skaaning Jensen; Dorte Strøbaek; Søren-Peter Olesen; palle christophersen
Activation of the human, intermediate-conductance, Ca2+-activated K+ channel by methylxanthines.
Pflügers Archiv : European journal of physiology 2000;440(6):809-18.
2000: KA Pedersen; Nanna K Jørgensen; Bo Skaaning Jensen; Søren-Peter Olesen
Inhibition of the human intermediate-conductance, Ca2+-activated K+ channel by intracellular acidification.
Pflügers Archiv : European journal of physiology 2000;440(1):153-6.
2000: Dorte Strøbaek; Tino Dyhring; palle christophersen; Philip K Ahring; Søren-Peter Olesen
Pharmacological characterization of small-conductance Ca(2+)-activated K(+) channels stably expressed in HEK 293 cells.
British journal of pharmacology 2000;129(5):991-9.
1999: Bo Skaaning Jensen; N Odum; Nanna K Jorgensen; palle christophersen; Søren-Peter Olesen
Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(19):10917-21.
1999: KA Pedersen; Rikke Louise Schrøder; B Skaaning-Jensen; Dorte Strøbaek; Søren-Peter Olesen; palle christophersen
Activation of the human intermediate-conductance Ca(2+)-activated K(+) channel by 1-ethyl-2-benzimidazolinone is strongly Ca(2+)-dependent.
Biochimica et biophysica acta 1999;1420(1-2):231-40.
1999: Tino Dyhring; Bo Skaaning Jensen; Dorte Strøbaek; palle christophersen; Søren-Peter Olesen; Philip K Ahring
Functional characterization of a cloned human intermediate-conductance Ca(2+)-activated K+ channel.
Annals of the New York Academy of Sciences 1999;868():423-6.
1999: Lone Bang; JE Nielsen-Kudsk; Nicolai Gruhn; SA Theilgaard; Søren-Peter Olesen; Søren Boesgaard; Jan Aldershvile
Vascular smooth muscle contraction is an independent regulator of endothelial nitric oxide production.
Scandinavian cardiovascular journal : SCJ 1999;33(2):33-78.
1998: Lone Bang; JE Nielsen-Kudsk; Nicolai Gruhn; Simon Trautner; SA Theilgaard; Søren-Peter Olesen; Søren Boesgaard; Jan Aldershvile
Hydralazine-induced vasodilation involves opening of high conductance Ca2+-activated K+ channels.
European journal of pharmacology 1998;361(1):43-9.
1998: Bo Skaaning Jensen; D Strobaek; palle christophersen; Tino Dyhring; C Hansen; A Silahtaroglu; Søren-Peter Olesen; Philip K Ahring
Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.
The American journal of physiology 1998;275(3 Pt 1):C848-56.
1998: Nicolai Gruhn; JE Nielsen-Kudsk; SA Theilgaard; Lone Bang; Søren-Peter Olesen; Jan Aldershvile
Coronary vasorelaxant effect of levosimendan, a new inodilator with calcium-sensitizing properties.
Journal of cardiovascular pharmacology 1998;31(5):741-9.
1998: Søren-Peter Olesen; J Drejer; O Axelsson; P Moldt; Lone Bang; JE Nielsen-Kudsk; R Busse; A Mülsch
Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase.
British journal of pharmacology 1998;123(2):299-309.
1997: Philip K Ahring; Dorte Strøbaek; palle christophersen; Søren-Peter Olesen; Teit E Johansen
Stable expression of the human large-conductance Ca2+-activated K+ channel alpha- and beta-subunits in HEK293 cells.
FEBS letters 1997;415(1):67-70.
1997: Søren-Peter Olesen; A Møller; P I Mordvintcev; R Busse; A Mülsch
Regional measurements of NO formed in vivo during brain ischemia.
Acta neurologica Scandinavica 1997;95(4):219-24.
1997: N R Holm; palle christophersen; Søren-Peter Olesen; Steen Gammeltoft
Activation of calcium-dependent potassium channels in mouse [correction of rat] brain neurons by neurotrophin-3 and nerve growth factor.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(3):1002-6.
1996: Dorte Strøbaek; palle christophersen; Steen Dissing; Søren-Peter Olesen
ATP activates K and Cl channels via purinoceptor-mediated release of Ca2+ in human coronary artery smooth muscle.
The American journal of physiology 1996;271(5 Pt 1):C1463-71.
1996: Julie Tseng-Crank; N Godinot; Teit E Johansen; Philip K Ahring; Dorte Strøbaek; R Mertz; C D Foster; Søren-Peter Olesen; Peter H Reinhart
Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9200-5.
1996: Dorte Strøbaek; Søren-Peter Olesen; palle christophersen; Steen Dissing
P2-purinoceptor-mediated formation of inositol phosphates and intracellular Ca2+ transients in human coronary artery smooth muscle cells.
British journal of pharmacology 1996;118(7):1645-52.
1996: Dorte Strøbaek; palle christophersen; N R Holm; P Moldt; Philip K Ahring; Teit E Johansen; Søren-Peter Olesen
Modulation of the Ca(2+)-dependent K+ channel, hslo, by the substituted diphenylurea NS 1608, paxilline and internal Ca2+.
Neuropharmacology 1996;35(7):903-14.
1994: Alexander Mülsch; Rudi Busse; P I Mordvintcev; Anatoly F Vanin; E O Nielsen; J Scheel-Krüger; Søren-Peter Olesen
Nitric oxide promotes seizure activity in kainate-treated rats.
Neuroreport 1994;5(17):2325-8.
1994: M C McKay; Steven I Dworetzky; Nicholas A Meanwell; Søren-Peter Olesen; Peter H Reinhart; I B Levitan; John P Adelman; Valentin K Gribkoff
Opening of large-conductance calcium-activated potassium channels by the substituted benzimidazolone NS004.
Journal of neurophysiology 1994;71(5):1873-82.
1994: Søren-Peter Olesen; E Munch; F Wätjen; Jørgen Drejer
NS 004--an activator of Ca(2+)-dependent K+ channels in cerebellar granule cells.
Neuroreport 1994;5(8):1001-4.
1994: Søren-Peter Olesen; E Munch; P Moldt; Jørgen Drejer
Selective activation of Ca(2+)-dependent K+ channels by novel benzimidazolone.
European journal of pharmacology 1994;251(1):53-9.