FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Peter Olinga

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Physiology

Cell Survival

Disorders

Procedures

Co-author Network

Publications

TOP 3
I M Westra; B T Pham; G M M Groothuis; Peter Olinga
Evaluation of fibrosis in precision-cut tissue slices.
Alison E M Vickers; Robyn Fisher; Peter Olinga; Sharon Dial
Repair pathways evident in human liver organ slices.
MG Elferink; Peter Olinga; E M van Leeuwen; S Bauerschmidt; J Polman; W G Schoonen; S H Heisterkamp; G M M Groothuis
Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Peter Olinga (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: I M Westra; B T Pham; G M M Groothuis; Peter Olinga
Evaluation of fibrosis in precision-cut tissue slices.
Xenobiotica; the fate of foreign compounds in biological systems 2013;43(1):98-112.
2011: Alison E M Vickers; Robyn Fisher; Peter Olinga; Sharon Dial
Repair pathways evident in human liver organ slices.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(7):1485-92.
2011: MG Elferink; Peter Olinga; E M van Leeuwen; S Bauerschmidt; J Polman; W G Schoonen; S H Heisterkamp; G M M Groothuis
Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes.
Toxicology and applied pharmacology 2011;253(1):57-69.
2010: Inge A M De Graaf; Peter Olinga; Marina H de Jager; Marjolijn T Merema; Ruben de Kanter; Esther G van de Kerkhof; Geny M M Groothuis
Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies.
Nature protocols 2010;5(9):1540-51.
2010: Courtney S Schaffert; Michael J Duryee; Robert G Bennett; Amy L DeVeney; Dean J Tuma; Peter Olinga; Karen C Easterling; Geoffrey M Thiele; Lynell W Klassen
Exposure of precision-cut rat liver slices to ethanol accelerates fibrogenesis.
American journal of physiology. Gastrointestinal and liver physiology 2010;299(3):G661-8.
2008: Lynell W Klassen; Geoffrey M Thiele; Michael J Duryee; Courtney S Schaffert; Amy L DeVeney; Carlos D Hunter; Peter Olinga; Dean J Tuma
An in vitro method of alcoholic liver injury using precision-cut liver slices from rats.
Biochemical pharmacology 2008;76(3):426-36.
2008: M G L Elferink; Peter Olinga; Annelies L Draaisma; Marjolijn T Merema; S Bauerschmidt; J Polman; W G Schoonen; Geny M M Groothuis
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity.
Toxicology and applied pharmacology 2008;229(3):300-9.
2008: Peter Olinga; M G L Elferink; Annelies L Draaisma; Marjolijn T Merema; J V Castell; G Pérez; Geny M M Groothuis
Coordinated induction of drug transporters and phase I and II metabolism in human liver slices.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;33(4-5):380-9.
2008: Marja van de Bovenkamp; Geny M M Groothuis; Dirk K F Meijer; Peter Olinga
Liver slices as a model to study fibrogenesis and test the effects of anti-fibrotic drugs on fibrogenic cells in human liver.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(3):771-8.
2007: Inge Am de Graaf; Geny M M Groothuis; Peter Olinga
Precision-cut tissue slices as a tool to predict metabolism of novel drugs.
Expert opinion on drug metabolism & toxicology 2007;3(6):879-98.
2007: Marja van de Bovenkamp; Geny M M Groothuis; Dirk K F Meijer; Peter Olinga
Liver fibrosis in vitro: cell culture models and precision-cut liver slices.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(4):545-57.
2006: Marja van de Bovenkamp; Geny M M Groothuis; Dirk K F Meijer; Peter Olinga
Precision-cut fibrotic rat liver slices as a new model to test the effects of anti-fibrotic drugs in vitro.
Journal of hepatology 2006;45(5):696-703.
2006: Marja van de Bovenkamp; Geny M M Groothuis; Dirk K F Meijer; Maarten J H Slooff; Peter Olinga
Human liver slices as an in vitro model to study toxicity-induced hepatic stellate cell activation in a multicellular milieu.
Chemico-biological interactions 2006;162(1):62-9.
2006: Werner I Hagens; Peter Olinga; Dirk K F Meijer; Geny M M Groothuis; Leonie Beljaars; Klaas Poelstra
Gliotoxin non-selectively induces apoptosis in fibrotic and normal livers.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(2):232-9.
2006: Johannes H Proost; Leonie Beljaars; Peter Olinga; Pieter J Swart; Mirjam E Kuipers; Catharina Reker-Smit; Geny M M Groothuis; Dirk K F Meijer
Prediction of the pharmacokinetics of succinylated human serum albumin in man from in vivo disposition data in animals and in vitro liver slice incubations.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;27(2-3):123-32.
2006: Marianne G Rots; Marieke G L Elferink; Willemijn M Gommans; D Oosterhuis; Johanna A C Schalk; DT Curiel; Peter Olinga; Hidde J Haisma; Geny M M Groothuis
An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents.
The journal of gene medicine 2006;8(1):35-41.
2005: Alan F Hofmann; Salam F Zakko; Marco Lira; Carlo Clerici; lee hagey; K Karel Lambert; Joseph H Steinbach; Claudio D Schteingart; Peter Olinga; Geny M M Groothuis
Novel biotransformation and physiological properties of norursodeoxycholic acid in humans.
Hepatology (Baltimore, Md.) 2005;42(6):1391-8.
2005: Nils A 't Hart; Arjan van der Plaats; Alexander Faber; Henri G D Leuvenink; Peter Olinga; Janneke Wiersema-Buist; Gijsbertus J Verkerke; Gerhard Rakhorst; Rutger J Ploeg
Oxygenation during hypothermic rat liver preservation: an in vitro slice study to demonstrate beneficial or toxic oxygenation effects.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005;11(11):1403-11.
2005: Marja van de Bovenkamp; Geny M M Groothuis; Annelies L Draaisma; Marjolijn T Merema; Judith I Bezuijen; Marit J van Gils; Dirk K F Meijer; Scott L Friedman; Peter Olinga
Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu.
Toxicological sciences : an official journal of the Society of Toxicology 2005;85(1):632-8.
2005: Peter Olinga; Joost A B van der Hoeven; Marjolijn T Merema; Rennie L Freund; Rutger J Ploeg; Geny M M Groothuis
The influence of brain death on liver function.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(1):109-16.
2005: L G Koudstaal; N A 't Hart; Anke Van den Berg; Peter Olinga; Harry van Goor; Rutger J Ploeg; Henri G D Leuvenink
Brain death causes structural and inflammatory changes in donor intestine.
Transplantation proceedings 2005;37(1):448-9.
2004: Alison E M Vickers; Muriel Saulnier; Elba Cruz; Marjolijn T Merema; Kristine Rose; Philip Bentley; Peter Olinga
Organ slice viability extended for pathway characterization: an in vitro model to investigate fibrosis.
Toxicological sciences : an official journal of the Society of Toxicology 2004;82(2):534-44.
2004: Nils A 't Hart; Arjan van der Plaats; Henri G D Leuvenink; Janneke Wiersema-Buist; Peter Olinga; Marja J A van Luyn; Gijsbertus J Verkerke; Gerhard Rakhorst; Rutger J Ploeg
Initial blood washout during organ procurement determines liver injury and function after preservation and reperfusion.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(11):1836-44.
2004: Marieke G L Elferink; Peter Olinga; Annelies L Draaisma; Marjolijn T Merema; Klaas Nico Faber; Maarten J H Slooff; Dirk K F Meijer; Geny M M Groothuis
LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(5):G1008-16.
2004: Alex Y Hui; Andrew J Dannenberg; Joseph J Y Sung; Kotha Subbaramaiah; Baoheng Du; Peter Olinga; Scott L Friedman
Prostaglandin E2 inhibits transforming growth factor beta 1-mediated induction of collagen alpha 1(I) in hepatic stellate cells.
Journal of hepatology 2004;41(2):251-8.
2002: Ruben de Kanter; Marina H de Jager; Annelies L Draaisma; J U Jurva; Peter Olinga; Dirk K F Meijer; Geny M M Groothuis
Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices.
Xenobiotica; the fate of foreign compounds in biological systems 2002;32(5):349-62.
2001: Leonie Beljaars; Peter Olinga; Grietje Molema; Pieter De Bleser; Albert Geerts; Geny M M Groothuis; Dirk K F Meijer; Klaas Poelstra
Characteristics of the hepatic stellate cell-selective carrier mannose 6-phosphate modified albumin (M6P(28)-HSA).
Liver 2001;21(5):320-8.
2001: Barbro Melgert; Peter Olinga; Jan-Metske van der Laan; Betty Weert; J Cho; Detlef Schuppan; Geny M M Groothuis; Dirk K F Meijer; Klaas Poelstra
Targeting dexamethasone to Kupffer cells: effects on liver inflammation and fibrosis in rats.
Hepatology (Baltimore, Md.) 2001;34(4 Pt 1):719-28.
2001: Peter Olinga; Marjolijn T Merema; Marina H de Jager; F Derks; Barbro Melgert; Han Moshage; Maarten J H Slooff; Dirk K F Meijer; Klaas Poelstra; Geny M M Groothuis
Rat liver slices as a tool to study LPS-induced inflammatory response in the liver.
Journal of hepatology 2001;35(2):187-94.
2001: Barbro Melgert; Peter Olinga; Betty Weert; Maarten J H Slooff; Dirk K F Meijer; Klaas Poelstra; Geny M M Groothuis
Cellular distribution and handling of liver-targeting preparations in human livers studied by a liver lobe perfusion.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(6):361-7.
2001: Barbro Melgert; Peter Olinga; Betty Weert; Maarten J H Slooff; Dirk K F Meijer; Klaas Poelstra; Geny M M Groothuis
Cellular distribution and handling of liver-targeting preparations in human livers studied by a liver lobe perfusion.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(4 Pt 1):361-7.
2001: Adriana M Kas-Deelen; Winston W Bakker; Peter Olinga; J Visser; Eltjo F de Maar; Willem J Van Son; T Hauw The; Martin C Harmsen
Cytomegalovirus infection increases the expression and activity of ecto-ATPase (CD39) and ecto-5'nucleotidase (CD73) on endothelial cells.
FEBS letters 2001;491(1-2):21-5.
2001: Peter Olinga; IH Hof; Marjolijn T Merema; M Smit; Marina H de Jager; Pieter J Swart; Maarten J H Slooff; Dirk K F Meijer; Geny M M Groothuis
The applicability of rat and human liver slices to the study of mechanisms of hepatic drug uptake.
Journal of pharmacological and toxicological methods 2001;45(1):55-63.
2000: Peter Olinga; John K Maring; Marjolijn T Merema; IH Hof; Maarten J H Slooff; Dirk K F Meijer; Geny M M Groothuis
The capability of isolated hepatocytes and liver slices of donor livers to predict graft function after liver transplantation.
Liver 2000;20(5):374-80.
2000: Barbro Melgert; Peter Olinga; V K Jack; Grietje Molema; Dirk K F Meijer; Klaas Poelstra
Dexamethasone coupled to albumin is selectively taken up by rat nonparenchymal liver cells and attenuates LPS-induced activation of hepatic cells.
Journal of hepatology 2000;32(4):603-11.
2000: Maarten W N Nijsten; Peter Olinga; T Hauw The; E G de Vries; Heimen Schraffordt Koops; Geny M M Groothuis; Pieter C Limburg; Henk Jan ten Duis; Han Moshage; H J Hoekstra; Johan Bijzet; Jan H Zwaveling
Procalcitonin behaves as a fast responding acute phase protein in vivo and in vitro.
Critical care medicine 2000;28(2):458-61.
1999: Ruben de Kanter; Peter Olinga; Marina H de Jager; Marjolijn T Merema; Dirk K F Meijer; G M Groothius
Organ slices as an in vitro test system for drug metabolism in human liver, lung and kidney.
Toxicology in vitro : an international journal published in association with BIBRA 1999;13(4-5):737-44.
1999: Leonie Beljaars; Grietje Molema; Betty Weert; H Bonnema; Peter Olinga; Geny M M Groothuis; Dirk K F Meijer; Klaas Poelstra
Albumin modified with mannose 6-phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells.
Hepatology (Baltimore, Md.) 1999;29(5):1486-93.
1998: C H J Verhoeven; S F M Krebbers; G N Wagenaars; C J Booy; Geny M M Groothuis; Peter Olinga; R M E Vos
In vitro and in vivo metabolism of the progestagen Org 30659 in several species.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(11):1102-12.
1998: Peter Olinga; Marjolijn T Merema; G W Sandker; Maarten J H Slooff; Dirk K F Meijer; Geny M M Groothuis
Uptake of taurocholic acid in human hepatocytes isolated from livers of donors of different age.
Journal of pediatric gastroenterology and nutrition 1998;27(3):366-8.
1998: Peter Olinga; Marjolijn T Merema; IH Hof; Maarten J H Slooff; Johannes H Proost; Dirk K F Meijer; Geny M M Groothuis
Characterization of the uptake of rocuronium and digoxin in human hepatocytes: carrier specificity and comparison with in vivo data.
The Journal of pharmacology and experimental therapeutics 1998;285(2):506-10.
1998: Peter Olinga; Marjolijn T Merema; IH Hof; Marina H de Jager; K P De Jong; Maarten J H Slooff; Dirk K F Meijer; Geny M M Groothuis
Effect of cold and warm ischaemia on drug metabolism in isolated hepatocytes and slices from human and monkey liver.
Xenobiotica; the fate of foreign compounds in biological systems 1998;28(4):349-60.
1998: Ruben de Kanter; Peter Olinga; IH Hof; Marina H de Jager; W A Verwillegen; Maarten J H Slooff; Henk J Koster; Dirk K F Meijer; Geny M M Groothuis
A rapid and simple method for cryopreservation of human liver slices.
Xenobiotica; the fate of foreign compounds in biological systems 1998;28(3):225-34.
1998: Peter Olinga; Marjolijn T Merema; IH Hof; K P de Jong; Maarten J H Slooff; Dirk K F Meijer; Geny M M Groothuis
Effect of human liver source on the functionality of isolated hepatocytes and liver slices.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(1):5-11.
1997: Peter Olinga; K Groen; IH Hof; Ruben de Kanter; Henk J Koster; W R Leeman; A A Rutten; K Van Twillert; Geny M M Groothuis
Comparison of five incubation systems for rat liver slices using functional and viability parameters.
Journal of pharmacological and toxicological methods 1997;38(2):59-69.
1997: Peter Olinga; Marjolijn T Merema; Maarten J H Slooff; Dirk K F Meijer; Geny M M Groothuis
Influence of 48 hours of cold storage in University of Wisconsin organ preservation solution on metabolic capacity of rat hepatocytes.
Journal of hepatology 1997;27(4):738-43.
1997: Peter Olinga; John K Maring; Geny M M Groothuis; Koos Kranenburg; Marjolijn T Merema; IH Hof; Dirk K F Meijer; Maarten J H Slooff
Value of the in vitro or in vivo monoethylglycinexylidide test for predicting liver graft function.
Transplantation 1997;64(1):60-5.
1997: Peter Olinga; Dirk K F Meijer; Maarten J H Slooff; Geny M M Groothuis
Liver slices in in vitro pharmacotoxicology with special reference to the use of human liver tissue.
Toxicology in vitro : an international journal published in association with BIBRA 1997;12(1):77-100.
1994: G W Sandker; B Weert; Peter Olinga; Henk Wolters; Maarten J H Slooff; Dirk K F Meijer; Geny M M Groothuis
Characterization of transport in isolated human hepatocytes. A study with the bile acid taurocholic acid, the uncharged ouabain and the organic cations vecuronium and rocuronium.
Biochemical pharmacology 1994;47(12):2193-200.