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Baldomero Olivera

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Amino Acid Sequence

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Publications

TOP 3
Peraud Olivier; Biggs Jason S; Hughen Ronald W; Light Alan R; Concepcion Gisela P; Olivera Baldomero M; Schmidt Eric W
Microhabitats within venomous cone snails contain diverse actinobacteria.
Twede Vernon D; Teichert Russell W; Walker Craig S; Gruszczynski Pawel; Kazmierkiewicz Rajmund; Bulaj Grzegorz; Olivera Baldomero M
Conantokin-Br from Conus brettinghami and selectivity determinants for the NR2D subunit of the NMDA receptor.
Twede Vernon D; Miljanich George; Olivera Baldomero M; Bulaj Grzegorz
Neuroprotective and cardioprotective conopeptides: an emerging class of drug leads.

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All Publications

2009: Peraud Olivier; Biggs Jason S; Hughen Ronald W; Light Alan R; Concepcion Gisela P; Olivera Baldomero M; Schmidt Eric W
Microhabitats within venomous cone snails contain diverse actinobacteria.
Applied and environmental microbiology 2009;75(21):6820-6.
2009: Twede Vernon D; Teichert Russell W; Walker Craig S; Gruszczynski Pawel; Kazmierkiewicz Rajmund; Bulaj Grzegorz; Olivera Baldomero M
Conantokin-Br from Conus brettinghami and selectivity determinants for the NR2D subunit of the NMDA receptor.
Biochemistry 2009;48(19):4063-73.
2009: Twede Vernon D; Miljanich George; Olivera Baldomero M; Bulaj Grzegorz
Neuroprotective and cardioprotective conopeptides: an emerging class of drug leads.
Current opinion in drug discovery & development 2009;12(2):231-9.
2009: Han Tiffany S; Zhang Min-Min; Walewska Aleksandra; Gruszczynski Pawel; Robertson Charles R; Cheatham Thomas E; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz
Structurally minimized mu-conotoxin analogues as sodium channel blockers: implications for designing conopeptide-based therapeutics.
ChemMedChem 2009;4(3):406-14.
2009: Aguilar Manuel B; de la Rosa Ruby A Chan; Falcón Andrés; Olivera Baldomero M; Heimer de la Cotera Edgar P
Peptide pal9a from the venom of the turrid snail Polystira albida from the Gulf of Mexico: purification, characterization, and comparison with P-conotoxin-like (framework IX) conoidean peptides.
Peptides 2009;30(3):467-76.
2009: Khoo Keith K; Feng Zhi-Ping; Smith Brian J; Zhang Min-Min; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion.
Biochemistry 2009;48(6):1210-9.
2009: Zhang Min-Min; McArthur Jeff R; Azam Layla; Bulaj Grzegorz; Olivera Baldomero M; French Robert J; Yoshikami Doju
Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels.
Channels (Austin, Tex.) 2009;3(1):32-8.
2009: Holford Mandë; Zhang Min-Min; Gowd K Hanumae; Azam Layla; Green Brad R; Watkins Maren; Ownby John-Paul; Yoshikami Doju; Bulaj Grzegorz; Olivera Baldomero M
Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus.
Toxicon : official journal of the International Society on Toxinology 2009;53(1):90-8.
2009: Holford Mandë; Puillandre Nicolas; Modica Maria Vittoria; Watkins Maren; Collin Rachel; Bermingham Eldredge; Olivera Baldomero M
Correlating molecular phylogeny with venom apparatus occurrence in Panamic auger snails (Terebridae).
PloS one 2009;4(11):e7667.
2009: Walewska Aleksandra; Zhang Min-Min; Skalicky Jack J; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz
Integrated oxidative folding of cysteine/selenocysteine containing peptides: improving chemical synthesis of conotoxins.
Angewandte Chemie (International ed. in English) 2009;48(12):2221-4.
2008: Kantor Yuri I; Puillandre Nicolas; Olivera Baldomero M; Bouchet Philippe
Morphological proxies for taxonomic decision in turrids (mollusca, neogastropoda): a test of the value of shell and radula characters using molecular data.
Zoological science 2008;25(11):1156-70.
2008: Walewska Aleksandra; Skalicky Jack J; Davis Darrell R; Zhang Min-Min; Lopez-Vera Estuardo; Watkins Maren; Han Tiffany S; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz
NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIA.
Journal of the American Chemical Society 2008;130(43):14280-6.
2008: Yao Shenggen; Zhang Min-Min; Yoshikami Doju; Azam Layla; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA.
Biochemistry 2008;47(41):10940-9.
2008: Gowd Konkallu Hanumae; Twede Vernon; Watkins Maren; Krishnan K S; Teichert Russell W; Bulaj Grzegorz; Olivera Baldomero M
Conantokin-P, an unusual conantokin with a long disulfide loop.
Toxicon : official journal of the International Society on Toxinology 2008;52(2):203-13.
2008: Imperial Julita S; Chen Ping; Sporning Annett; Terlau Heinrich; Daly Norelle L; Craik David J; Alewood Paul F; Olivera Baldomero M
Tyrosine-rich conopeptides affect voltage-gated K+ channels.
The Journal of biological chemistry 2008;283(34):23026-32.
2008: Biggs Jason S; Olivera Baldomero M; Kantor Yuri I
Alpha-conopeptides specifically expressed in the salivary gland of Conus pulicarius.
Toxicon : official journal of the International Society on Toxinology 2008;52(1):101-5.
2008: Chen Ping; Garrett James E; Watkins Maren; Olivera Baldomero M
Purification and characterization of a novel excitatory peptide from Conus distans venom that defines a novel gene superfamily of conotoxins.
Toxicon : official journal of the International Society on Toxinology 2008;52(1):139-45.
2008: Fiedler Brian; Zhang Min-Min; Buczek Oga; Azam Layla; Bulaj Grzegorz; Norton Raymond S; Olivera Baldomero M; Yoshikami Doju
Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7.
Biochemical pharmacology 2008;75(12):2334-44.
2008: Liu Yun; Padgett Daniel; Takahashi Masazumi; Li Hongqiao; Sayeed Ayaz; Teichert Russell W; Olivera Baldomero M; McArdle Joseph J; Green William N; Lin Weichun
Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning.
Development (Cambridge, England) 2008;135(11):1957-67.
2008: Oppenheim Ronald W; Calderó Jordi; Cuitat Doloros; Esquerda Josep; McArdle Joseph J; Olivera Baldomero M; Prevette David; Teichert Russell W
The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle-specific nicotinic acetylcholine receptor.
Developmental neurobiology 2008;68(7):972-80.
2008: Ellison Michael; Feng Zhi-Ping; Park Anthony J; Zhang Xuecheng; Olivera Baldomero M; McIntosh J Michael; Norton Raymond S
Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.
Journal of molecular biology 2008;377(4):1216-27.
2008: Heralde Francisco M; Imperial Julita; Bandyopadhyay Pradip K; Olivera Baldomero M; Concepcion Gisela P; Santos Ameurfina D
A rapidly diverging superfamily of peptide toxins in venomous Gemmula species.
Toxicon : official journal of the International Society on Toxinology 2008;51(5):890-7.
2008: Zugasti-Cruz Alejandro; Aguilar Manuel B; Falcón Andrés; Olivera Baldomero M; Heimer de la Cotera Edgar P
Two new 4-Cys conotoxins (framework 14) of the vermivorous snail Conus austini from the Gulf of Mexico with activity in the central nervous system of mice.
Peptides 2008;29(2):179-85.
2008: Aguilar Manuel B; Luna-Ramírez Karen S; Echeverría Daniel; Falcón Andrés; Olivera Baldomero M; Heimer de la Cotera Edgar P; Maillo María
Conorfamide-Sr2, a gamma-carboxyglutamate-containing FMRFamide-related peptide from the venom of Conus spurius with activity in mice and mollusks.
Peptides 2008;29(2):186-95.
2008: Lopez-Vera Estuardo; Walewska Aleksandra; Skalicky Jack J; Olivera Baldomero M; Bulaj Grzegorz
Role of hydroxyprolines in the in vitro oxidative folding and biological activity of conotoxins.
Biochemistry 2008;47(6):1741-51.
2008: Lluisma Arturo O; López-Vera Estuardo; Bulaj Grzegorz; Watkins Maren; Olivera Baldomero M
Characterization of a novel psi-conotoxin from Conus parius Reeve.
Toxicon : official journal of the International Society on Toxinology 2008;51(2):174-80.
2008: Buczek Olga; Jimenez Elsie C; Yoshikami Doju; Imperial Julita S; Watkins Maren; Morrison Alex; Olivera Baldomero M
I(1)-superfamily conotoxins and prediction of single D-amino acid occurrence.
Toxicon : official journal of the International Society on Toxinology 2008;51(2):218-29.
2008: Bulaj Grzegorz; Olivera Baldomero M
Folding of conotoxins: formation of the native disulfide bridges during chemical synthesis and biosynthesis of Conus peptides.
Antioxidants & redox signaling 2008;10(1):141-55.
2008: Bandyopadhyay Pradip K; Stevenson Bradford J; Ownby John-Paul; Cady Matthew T; Watkins Maren; Olivera Baldomero M
The mitochondrial genome of Conus textile, coxI-coxII intergenic sequences and Conoidean evolution.
Molecular phylogenetics and evolution 2008;46(1):215-23.
2008: Han Tiffany S; Teichert Russell W; Olivera Baldomero M; Bulaj Grzegorz
Conus venoms - a rich source of peptide-based therapeutics.
Current pharmaceutical design 2008;14(24):2462-79.
2008: Teichert Russell W; Garcia Carmen C; Potian Joseph G; Schmidt James J; Witzemann Veit; Olivera Baldomero M; McArdle Joseph J
Peptide-toxin tools for probing the expression and function of fetal and adult subtypes of the nicotinic acetylcholine receptor.
Annals of the New York Academy of Sciences 2008;1132():61-70.
2007: Teichert Russell W; Jimenez Elsie C; Twede Vernon; Watkins Maren; Hollmann Michael; Bulaj Grzegorz; Olivera Baldomero M
Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors.
The Journal of biological chemistry 2007;282(51):36905-13.
2007: Imperial Julita S; Kantor Yuri; Watkins Maren; Heralde Francisco M; Stevenson Bradford; Chen Ping; Hansson Karin; Stenflo Johan; Ownby John-Paul; Bouchet Philippe; Olivera Baldomero M
Venomous auger snail Hastula (Impages) hectica (Linnaeus, 1758): molecular phylogeny, foregut anatomy and comparative toxinology.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2007;308(6):744-56.
2007: Biggs Jason S; Rosenfeld Yosef; Shai Yechiel; Olivera B M
Conolysin-Mt: a conus peptide that disrupts cellular membranes.
Biochemistry 2007;46(44):12586-93.
2007: Olivera Baldomero M; Teichert Russell W
Diversity of the neurotoxic Conus peptides: a model for concerted pharmacological discovery.
Molecular interventions 2007;7(5):251-60.
2007: Zhang Min-Min; Green Brad R; Catlin Philip; Fiedler Brian; Azam Layla; Chadwick Ashley; Terlau Heinrich; McArthur Jeff R; French Robert J; Gulyas Josef; Rivier Jean E; Smith Brian J; Norton Raymond S; Olivera Baldomero M; Yoshikami Doju; Bulaj Grzegorz
Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.
The Journal of biological chemistry 2007;282(42):30699-706.
2007: Buczek Olga; Wei Daxiu; Babon Jeffrey J; Yang Xiaodong; Fiedler Brian; Chen Ping; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Biochemistry 2007;46(35):9929-40.
2007: Leipold Enrico; DeBie Herbert; Zorn Stefan; Borges Adolfo; Olivera Baldomero M; Terlau Heinrich; Heinemann Stefan H
muO conotoxins inhibit NaV channels by interfering with their voltage sensors in domain-2.
Channels (Austin, Tex.) 2007;1(4):253-62.
2007: Jimenez Elsie C; Olivera Baldomero M; Teichert Russell W
AlphaC-conotoxin PrXA: a new family of nicotinic acetylcholine receptor antagonists.
Biochemistry 2007;46(30):8717-24.
2007: Whiteaker Paul; Christensen Sean; Yoshikami Doju; Dowell Cheryl; Watkins Maren; Gulyas Jozsef; Rivier Jean; Olivera Baldomero M; McIntosh J Michael
Discovery, synthesis, and structure activity of a highly selective alpha7 nicotinic acetylcholine receptor antagonist.
Biochemistry 2007;46(22):6628-38.
2007: López-Vera Estuardo; Jacobsen Richard B; Ellison Michael; Olivera Baldomero M; Teichert Russell W
A novel alpha conotoxin (alpha-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors.
Toxicon : official journal of the International Society on Toxinology 2007;49(8):1193-9.
2007: Green Brad R; Catlin Philip; Zhang Min-Min; Fiedler Brian; Bayudan Wendi; Morrison Alex; Norton Raymond S; Smith Brian J; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz
Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity.
Chemistry & biology 2007;14(4):399-407.
2007: Teichert Russell W; Jacobsen Richard; Terlau Heinrich; Yoshikami Doju; Olivera Baldomero M
Discovery and characterization of the short kappaA-conotoxins: a novel subfamily of excitatory conotoxins.
Toxicon : official journal of the International Society on Toxinology 2007;49(3):318-28.
2007: Aguilar Manuel B; López-Vera Estuardo; Heimer de la Cotera Edgar P; Falcón Andrés; Olivera Baldomero M; Maillo María
I-conotoxins in vermivorous species of the West Atlantic: peptide sr11a from Conus spurius.
Peptides 2007;28(1):18-23.
2007: Luna-Ramírez Karen S; Aguilar Manuel B; Falcón Andrés; Heimer de la Cotera Edgar P; Olivera Baldomero M; Maillo María
An O-conotoxin from the vermivorous Conus spurius active on mice and mollusks.
Peptides 2007;28(1):24-30.
2007: Ellison Michael; Olivera Baldomero M
Alpha4/3 conotoxins: phylogenetic distribution, functional properties, and structure-function insights.
Chemical record (New York, N.Y.) 2007;7(6):341-53.
2006: Norton Raymond S; Olivera Baldomero M
Conotoxins down under.
Toxicon : official journal of the International Society on Toxinology 2006;48(7):780-98.
2006: Vincler Michelle; Wittenauer Shannon; Parker Renee; Ellison Michael; Olivera Baldomero M; McIntosh J Michael
Molecular mechanism for analgesia involving specific antagonism of alpha9alpha10 nicotinic acetylcholine receptors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17880-4.
2006: Chi Seung-Wook; Kim Do-Hyoung; Olivera Baldomero M; McIntosh J Michael; Han Kyou-Hoon
NMR structure determination of alpha-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold.
Biochemical and biophysical research communications 2006;349(4):1228-34.
2006: Olivera Baldomero M
Conus peptides: biodiversity-based discovery and exogenomics.
The Journal of biological chemistry 2006;281(42):31173-7.
2006: Wang Xueyong; Engisch Kathrin L; Teichert Russell W; Olivera Baldomero M; Pinter Martin J; Rich Mark M
Prolongation of evoked and spontaneous synaptic currents at the neuromuscular junction after activity blockade is caused by the upregulation of fetal acetylcholine receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(35):8983-7.
2006: Talley Todd T; Olivera Baldomero M; Han Kyou-Hoon; Christensen Sean B; Dowell Cheryl; Tsigelny Igor; Ho Kwok-Yiu; Taylor Palmer; McIntosh J Michael
Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors.
The Journal of biological chemistry 2006;281(34):24678-86.
2006: Imperial Julita S; Bansal Paramjit S; Alewood Paul F; Daly Norelle L; Craik David J; Sporning Annett; Terlau Heinrich; López-Vera Estuardo; Bandyopadhyay Pradip K; Olivera Baldomero M
A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.
Biochemistry 2006;45(27):8331-40.
2006: Bandyopadhyay Pradip K; Stevenson Bradford J; Cady Matthew T; Olivera Baldomero M; Wolstenholme David R
Complete mitochondrial DNA sequence of a Conoidean gastropod, Lophiotoma (Xenuroturris) cerithiformis: gene order and gastropod phylogeny.
Toxicon : official journal of the International Society on Toxinology 2006;48(1):29-43.
2006: Bulaj Grzegorz; Zhang Min-Min; Green Brad R; Fiedler Brian; Layer Richard T; Wei Sue; Nielsen Jacob S; Low Scott J; Klein Brian D; Wagstaff John D; Chicoine Linda; Harty T Patrick; Terlau Heinrich; Yoshikami Doju; Olivera Baldomero M
Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity.
Biochemistry 2006;45(23):7404-14.
2006: Chi Seung-Wook; Kim Do-Hyoung; Olivera Baldomero M; McIntosh J Michael; Han Kyou-Hoon
Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes.
Biochemical and biophysical research communications 2006;345(1):248-54.
2006: Bayrhuber Monika; Graf Roland; Ferber Michael; Zweckstetter Markus; Imperial Julita; Garrett James E; Olivera Baldomero M; Terlau Heinrich; Becker Stefan
Production of recombinant Conkunitzin-S1 in Escherichia coli.
Protein expression and purification 2006;47(2):640-4.
2006: Bandyopadhyay P K; Clark K; Stevenson B J; Rivier J E; Olivera B M; Golic K G; Rong Y S
Biochemical characterization of Drosophila gamma-glutamyl carboxylase and its role in fly development.
Insect molecular biology 2006;15(2):147-56.
2006: Zhang Min-Min; Fiedler Brian; Green Brad R; Catlin Phillip; Watkins Maren; Garrett James E; Smith Brian J; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz
Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels.
Biochemistry 2006;45(11):3723-32.
2006: Watkins Maren; Hillyard David R; Olivera Baldomero M
Genes expressed in a turrid venom duct: divergence and similarity to conotoxins.
Journal of molecular evolution 2006;62(3):247-56.
2006: Zugasti-Cruz Alejandro; Maillo María; López-Vera Estuardo; Falcón Andrés; Heimer de la Cotera Edgar P; Olivera Baldomero M; Aguilar Manuel B
Amino acid sequence and biological activity of a gamma-conotoxin-like peptide from the worm-hunting snail Conus austini.
Peptides 2006;27(3):506-11.
2006: Zorn Stefan; Leipold Enrico; Hansel Alfred; Bulaj Grzegorz; Olivera Baldomero M; Terlau Heinrich; Heinemann Stefan H
The muO-conotoxin MrVIA inhibits voltage-gated sodium channels by associating with domain-3.
FEBS letters 2006;580(5):1360-4.
2006: Ellison Michael; Haberlandt Christian; Gomez-Casati María Eugenia; Watkins Maren; Elgoyhen A Belén; McIntosh J Michael; Olivera Baldomero M
Alpha-RgIA: a novel conotoxin that specifically and potently blocks the alpha9alpha10 nAChR.
Biochemistry 2006;45(5):1511-7.
2006: Teichert Russell W; López-Vera Estuardo; Gulyas Jozsef; Watkins Maren; Rivier Jean; Olivera Baldomero M
Definition and characterization of the short alphaA-conotoxins: a single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor.
Biochemistry 2006;45(4):1304-12.
2005: Buczek O; Bulaj G; Olivera B M
Conotoxins and the posttranslational modification of secreted gene products.
Cellular and molecular life sciences : CMLS 2005;62(24):3067-79.
2005: Chi Seung-Wook; Lee Si-Hyung; Kim Do-Hyoung; Kim Jae-Sung; Olivera Baldomero M; McIntosh J Michael; Han Kyou-Hoon
Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors.
Biochemical and biophysical research communications 2005;338(4):1990-7.
2005: Aguilar Manuel B; López-Vera Estuardo; Ortiz Ernesto; Becerril Baltazar; Possani Lourival D; Olivera Baldomero M; Heimer de la Cotera Edgar P
A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues.
Biochemistry 2005;44(33):11130-6.
2005: Buczek Olga; Yoshikami Doju; Watkins Maren; Bulaj Grzegorz; Jimenez Elsie C; Olivera Baldomero M
Characterization of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily.
The FEBS journal 2005;272(16):4178-88.
2005: McIntosh J Michael; Plazas Paola V; Watkins Maren; Gomez-Casati María E; Olivera Baldomero M; Elgoyhen A Belén
A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors.
The Journal of biological chemistry 2005;280(34):30107-12.
2005: Leipold Enrico; Hansel Alfred; Olivera Baldomero M; Terlau Heinrich; Heinemann Stefan H
Molecular interaction of delta-conotoxins with voltage-gated sodium channels.
FEBS letters 2005;579(18):3881-4.
2005: Corpuz Gloria P; Jacobsen Richard B; Jimenez Elsie C; Watkins Maren; Walker Craig; Colledge Clark; Garrett James E; McDougal Owen; Li Wenqin; Gray William R; Hillyard David R; Rivier Jean; McIntosh J Michael; Cruz Lourdes J; Olivera Baldomero M
Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms.
Biochemistry 2005;44(22):8176-86.
2005: Bayrhuber Monika; Vijayan Vinesh; Ferber Michael; Graf Roland; Korukottu Jegannath; Imperial Julita; Garrett James E; Olivera Baldomero M; Terlau Heinrich; Zweckstetter Markus; Becker Stefan
Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization.
The Journal of biological chemistry 2005;280(25):23766-70.
2005: Verdier Laurent; Al-Sabi Ahmed; Rivier Jean E F; Olivera Baldomero M; Terlau Heinrich; Carlomagno Teresa
Identification of a novel pharmacophore for peptide toxins interacting with K+ channels.
The Journal of biological chemistry 2005;280(22):21246-55.
2005: Teichert Russell W; Jimenez Elsie C; Olivera Baldomero M
Alpha S-conotoxin RVIIIA: a structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors.
Biochemistry 2005;44(21):7897-902.
2005: Bulaj Grzegorz; West Peter J; Garrett James E; Watkins Maren; Zhang Min-Min; Norton Raymond S; Smith Brian J; Yoshikami Doju; Olivera Baldomero M
Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.
Biochemistry 2005;44(19):7259-65.
2005: Fuller Erika; Green Brad R; Catlin Phil; Buczek Olga; Nielsen Jacob S; Olivera Baldomero M; Bulaj Grzegorz
Oxidative folding of conotoxins sharing an identical disulfide bridging framework.
The FEBS journal 2005;272(7):1727-38.
2005: Garrett James E; Buczek Olga; Watkins Maren; Olivera Baldomero M; Bulaj Grzegorz
Biochemical and gene expression analyses of conotoxins in Conus textile venom ducts.
Biochemical and biophysical research communications 2005;328(1):362-7.
2005: Buczek Olga; Yoshikami Doju; Bulaj Grzegorz; Jimenez Elsie C; Olivera Baldomero M
Post-translational amino acid isomerization: a functionally important D-amino acid in an excitatory peptide.
The Journal of biological chemistry 2005;280(6):4247-53.
2005: Teichert Russell W; Rivier Jean; Torres Josep; Dykert John; Miller Charleen; Olivera Baldomero M
A uniquely selective inhibitor of the mammalian fetal neuromuscular nicotinic acetylcholine receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(3):732-6.
2005: Aguilar Manuel B; López-Vera Estuardo; Imperial Julita S; Falcón Andrés; Olivera Baldomero M; de la Cotera Edgar P Heimer
Putative gamma-conotoxins in vermivorous cone snails: the case of Conus delessertii.
Peptides 2005;26(1):23-7.
2005: Vianna Braga Maria Cristina; Konno Katsuhiro; Portaro Fernanda C V; de Freitas José Carlos; Yamane Tetsuo; Olivera Baldomero M; Pimenta Daniel C
Mass spectrometric and high performance liquid chromatography profiling of the venom of the Brazilian vermivorous mollusk Conus regius: feeding behavior and identification of one novel conotoxin.
Toxicon : official journal of the International Society on Toxinology 2005;45(1):113-22.
2005: Azam Layla; Dowell Cheryl; Watkins Maren; Stitzel Jerry A; Olivera Baldomero M; McIntosh J Michael
Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors.
The Journal of biological chemistry 2005;280(1):80-7.
2004: Ellison Michael; Gao Fan; Wang Hai-Long; Sine Steven M; McIntosh J Michael; Olivera Baldomero M
Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes.
Biochemistry 2004;43(51):16019-26.
2004: Kang James; Low William; Norberg Thomas; Meisenhelder Jill; Hansson Karin; Stenflo Johan; Zhou Guo-Ping; Imperial Julita; Olivera Baldomero M; Rigby Alan C; Craig A Grey
Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is alpha-D-Gal-(1-->3)-alpha-D-GalNAc.
European journal of biochemistry / FEBS 2004;271(23-24):4939-49.
2004: Jimenez Elsie C; Watkins Maren; Olivera Baldomero M
Multiple 6-bromotryptophan residues in a sleep-inducing peptide.
Biochemistry 2004;43(38):12343-8.
2004: Teichert Russell W; Rivier Jean; Dykert John; Cervini Laura; Gulyas Jozsef; Bulaj Grzegorz; Ellison Michael; Olivera Baldomero M
AlphaA-Conotoxin OIVA defines a new alphaA-conotoxin subfamily of nicotinic acetylcholine receptor inhibitors.
Toxicon : official journal of the International Society on Toxinology 2004;44(2):207-14.
2004: Al-Sabi Ahmed; Lennartz Dirk; Ferber Michael; Gulyas Jozsef; Rivier Jean E F; Olivera Baldomero M; Carlomagno Teresa; Terlau Heinrich
KappaM-conotoxin RIIIK, structural and functional novelty in a K+ channel antagonist.
Biochemistry 2004;43(27):8625-35.
2004: Boccaccio Anna; Conti Franco; Olivera Baldomero M; Terlau Heinrich
Binding of kappa-conotoxin PVIIA to Shaker K+ channels reveals different K+ and Rb+ occupancies within the ion channel pore.
The Journal of general physiology 2004;124(1):71-81.
2004: Ferber Michael; Al-Sabi Ahmed; Stocker Martin; Olivera Baldomero M; Terlau Heinrich
Identification of a mammalian target of kappaM-conotoxin RIIIK.
Toxicon : official journal of the International Society on Toxinology 2004;43(8):915-21.
2004: Chi Seung-Wook; Kim Do-Hyoung; Olivera Baldomero M; McIntosh J Michael; Han Kyou-Hoon
Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors.
The Biochemical journal 2004;380(Pt 2):347-52.
2004: Santos Ameurfina D; McIntosh J Michael; Hillyard David R; Cruz Lourdes J; Olivera Baldomero M
The A-superfamily of conotoxins: structural and functional divergence.
The Journal of biological chemistry 2004;279(17):17596-606.
2004: López-Vera Estuardo; Heimer de la Cotera Edgar P; Maillo María; Riesgo-Escovar Juan R; Olivera Baldomero M; Aguilar Manuel B
A novel structural class of toxins: the methionine-rich peptides from the venoms of turrid marine snails (Mollusca, Conoidea).
Toxicon : official journal of the International Society on Toxinology 2004;43(4):365-74.
2004: Buczek Olga; Olivera Baldomero M; Bulaj Grzegorz
Propeptide does not act as an intramolecular chaperone but facilitates protein disulfide isomerase-assisted folding of a conotoxin precursor.
Biochemistry 2004;43(4):1093-101.
2004: Terlau Heinrich; Olivera Baldomero M
Conus venoms: a rich source of novel ion channel-targeted peptides.
Physiological reviews 2004;84(1):41-68.
2004: Koch E Dietlind; Olivera Baldomero M; Terlau Heinrich; Conti Franco
The binding of kappa-Conotoxin PVIIA and fast C-type inactivation of Shaker K+ channels are mutually exclusive.
Biophysical journal 2004;86(1 Pt 1):191-209.
2003: Bulaj Grzegorz; Buczek Olga; Goodsell Ian; Jimenez Elsie C; Kranski Jessica; Nielsen Jacob S; Garrett James E; Olivera Baldomero M
Efficient oxidative folding of conotoxins and the radiation of venomous cone snails.
Proceedings of the National Academy of Sciences of the United States of America 2003;100 Suppl 2():14562-8.
2003: Keizer David W; West Peter J; Lee Erinna F; Yoshikami Doju; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA.
The Journal of biological chemistry 2003;278(47):46805-13.
2003: Chi Seung-Wook; Park Kyu-Hwan; Suk Jae-Eun; Olivera Baldomero M; McIntosh J Michael; Han Kyou-Hoon
Solution conformation of alphaA-conotoxin EIVA, a potent neuromuscular nicotinic acetylcholine receptor antagonist from Conus ermineus.
The Journal of biological chemistry 2003;278(43):42208-13.
2003: Imperial Julita S; Watkins Maren; Chen Ping; Hillyard David R; Cruz Lourdes J; Olivera Baldomero M
The augertoxins: biochemical characterization of venom components from the toxoglossate gastropod Terebra subulata.
Toxicon : official journal of the International Society on Toxinology 2003;42(4):391-8.
2003: Dowell Cheryl; Olivera Baldomero M; Garrett James E; Staheli Sarah T; Watkins Maren; Kuryatov Alexander; Yoshikami Doju; Lindstrom Jon M; McIntosh J Michael
Alpha-conotoxin PIA is selective for alpha6 subunit-containing nicotinic acetylcholine receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(24):8445-52.
2003: Van Wagoner Ryan M; Jacobsen Richard B; Olivera Baldomero M; Ireland Chris M
Characterization and three-dimensional structure determination of psi-conotoxin Piiif, a novel noncompetitive antagonist of nicotinic acetylcholine receptors.
Biochemistry 2003;42(21):6353-62.
2003: Jimenez Elsie C; Shetty Reshma P; Lirazan Marcelina; Rivier Jean; Walker Craig; Abogadie Fe C; Yoshikami Doju; Cruz Lourdes J; Olivera Baldomero M
Novel excitatory Conus peptides define a new conotoxin superfamily.
Journal of neurochemistry 2003;85(3):610-21.
2003: Ferber Michael; Sporning Annett; Jeserich Gunnar; DeLaCruz Richard; Watkins Maren; Olivera Baldomero M; Terlau Heinrich
A novel conus peptide ligand for K+ channels.
The Journal of biological chemistry 2003;278(4):2177-83.
2003: Ellison Michael; McIntosh J Michael; Olivera Baldomero M
Alpha-conotoxins ImI and ImII. Similar alpha 7 nicotinic receptor antagonists act at different sites.
The Journal of biological chemistry 2003;278(2):757-64.
2002: West Peter J; Bulaj Grzegorz; Garrett James E; Olivera Baldomero M; Yoshikami Doju
Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons.
Biochemistry 2002;41(51):15388-93.
2002: Miles Luke A; Dy Catherine Y; Nielsen Jake; Barnham Kevin J; Hinds Mark G; Olivera Baldomero M; Bulaj Grzegorz; Norton Raymond S
Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif.
The Journal of biological chemistry 2002;277(45):43033-40.
2002: Jimenez Elsie C; Donevan Sean; Walker Craig; Zhou Li-Ming; Nielsen Jake; Cruz Lourdes J; Armstrong Heather; White H Steve; Olivera Baldomero M
Conantokin-L, a new NMDA receptor antagonist: determinants for anticonvulsant potency.
Epilepsy research 2002;51(1-2):73-80.
2002: McIntosh J Michael; Dowell Cheryl; Watkins Maren; Garrett James E; Yoshikami Doju; Olivera Baldomero M
Alpha-conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors.
The Journal of biological chemistry 2002;277(37):33610-5.
2002: Lirazan M; Jimenez E C; Grey Craig A; Olivera B M; Cruz L J
Conophysin-R, a Conus radiatus venom peptide belonging to the neurophysin family.
Toxicon : official journal of the International Society on Toxinology 2002;40(7):901-8.
2002: Rong Yikang S; Titen Simon W; Xie Heng B; Golic Mary M; Bastiani Michael; Bandyopadhyay Pradip; Olivera Baldomero M; Brodsky Michael; Rubin Gerald M; Golic Kent G
Targeted mutagenesis by homologous recombination in D. melanogaster.
Genes & development 2002;16(12):1568-81.
2002: Maillo M; Aguilar M B; Lopéz-Vera E; Craig A G; Bulaj G; Olivera B M; Heimer de la Cotera E P
Conorfamide, a Conus venom peptide belonging to the RFamide family of neuropeptides.
Toxicon : official journal of the International Society on Toxinology 2002;40(4):401-7.
2002: Bandyopadhyay Pradip K; Garrett James E; Shetty Reshma P; Keate Tyler; Walker Craig S; Olivera Baldomero M
gamma -Glutamyl carboxylation: An extracellular posttranslational modification that antedates the divergence of molluscs, arthropods, and chordates.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1264-9.
2001: Espiritu D J; Watkins M; Dia-Monje V; Cartier G E; Cruz L J; Olivera B M
Venomous cone snails: molecular phylogeny and the generation of toxin diversity.
Toxicon : official journal of the International Society on Toxinology 2001;39(12):1899-916.
2001: Bulaj G; DeLaCruz R; Azimi-Zonooz A; West P; Watkins M; Yoshikami D; Olivera B M
Delta-conotoxin structure/function through a cladistic analysis.
Biochemistry 2001;40(44):13201-8.
2001: Kulak J M; McIntosh J M; Yoshikami D; Olivera B M
Nicotine-evoked transmitter release from synaptosomes: functional association of specific presynaptic acetylcholine receptors and voltage-gated calcium channels.
Journal of neurochemistry 2001;77(6):1581-9.
2001: Jimenez E C; Watkins M; Juszczak L J; Cruz L J; Olivera B M
Contryphans from Conus textile venom ducts.
Toxicon : official journal of the International Society on Toxinology 2001;39(6):803-8.
2001: Walker C S; Shetty R P; Clark K; Kazuko S G; Letsou A; Olivera B M; Bandyopadhyay P K
On a potential global role for vitamin K-dependent gamma-carboxylation in animal systems. Evidence for a gamma-glutamyl carboxylase in Drosophila.
The Journal of biological chemistry 2001;276(11):7769-74.
2001: Olivera B M; Cruz L J
Conotoxins, in retrospect.
Toxicon : official journal of the International Society on Toxinology 2001;39(1):7-14.
2000: McIntosh J M; Corpuz G O; Layer R T; Garrett J E; Wagstaff J D; Bulaj G; Vyazovkina A; Yoshikami D; Cruz L J; Olivera B M
Isolation and characterization of a novel conus peptide with apparent antinociceptive activity.
The Journal of biological chemistry 2000;275(42):32391-7.
2000: Jacobsen R B; Koch E D; Lange-Malecki B; Stocker M; Verhey J; Van Wagoner R M; Vyazovkina A; Olivera B M; Terlau H
Single amino acid substitutions in kappa-conotoxin PVIIA disrupt interaction with the shaker K+ channel.
The Journal of biological chemistry 2000;275(32):24639-44.
2000: Lirazan M B; Hooper D; Corpuz G P; Ramilo C A; Bandyopadhyay P; Cruz L J; Olivera B M
The spasmodic peptide defines a new conotoxin superfamily.
Biochemistry 2000;39(7):1583-8.
2000: White H S; McCabe R T; Armstrong H; Donevan S D; Cruz L J; Abogadie F C; Torres J; Rivier J E; Paarmann I; Hollmann M; Olivera B M
In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus.
The Journal of pharmacology and experimental therapeutics 2000;292(1):425-32.
1999: Olivera B M; Cruz L J; Yoshikami D
Effects of Conus peptides on the behavior of mice.
Current opinion in neurobiology 1999;9(6):772-7.
1999: Luo S; Nguyen T A; Cartier G E; Olivera B M; Yoshikami D; McIntosh J M
Single-residue alteration in alpha-conotoxin PnIA switches its nAChR subtype selectivity.
Biochemistry 1999;38(44):14542-8.
1999: Olivera B M
Conus venom peptides: correlating chemistry and behavior.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology 1999;185(4):353-9.
1999: Jacobsen R B; DelaCruz R G; Grose J H; McIntosh J M; Yoshikami D; Olivera B M
Critical residues influence the affinity and selectivity of alpha-conotoxin MI for nicotinic acetylcholine receptors.
Biochemistry 1999;38(40):13310-5.
1999: Walker C S; Steel D; Jacobsen R B; Lirazan M B; Cruz L J; Hooper D; Shetty R; DelaCruz R C; Nielsen J S; Zhou L M; Bandyopadhyay P; Craig A G; Olivera B M
The T-superfamily of conotoxins.
The Journal of biological chemistry 1999;274(43):30664-71.
1999: Jacobsen R B; Jimenez E C; De la Cruz R G; Gray W R; Cruz L J; Olivera B M
A novel D-leucine-containing Conus peptide: diverse conformational dynamics in the contryphan family.
The journal of peptide research : official journal of the American Peptide Society 1999;54(2):93-9.
1999: Terlau H; Boccaccio A; Olivera B M; Conti F
The block of Shaker K+ channels by kappa-conotoxin PVIIA is state dependent.
The Journal of general physiology 1999;114(1):125-40.
1999: Olivera B M; Walker C; Cartier G E; Hooper D; Santos A D; Schoenfeld R; Shetty R; Watkins M; Bandyopadhyay P; Hillyard D R
Speciation of cone snails and interspecific hyperdivergence of their venom peptides. Potential evolutionary significance of introns.
Annals of the New York Academy of Sciences 1999;870():223-37.
1999: Craig A G; Norberg T; Griffin D; Hoeger C; Akhtar M; Schmidt K; Low W; Dykert J; Richelson E; Navarro V; Mazella J; Watkins M; Hillyard D; Imperial J; Cruz L J; Olivera B M
Contulakin-G, an O-glycosylated invertebrate neurotensin.
The Journal of biological chemistry 1999;274(20):13752-9.
1999: McIntosh J M; Santos A D; Olivera B M
Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes.
Annual review of biochemistry 1999;68():59-88.
1999: McIntosh J M; Olivera B M; Cruz L J
Conus peptides as probes for ion channels.
Methods in enzymology 1999;294():605-24.
1998: Craig A G; Zafaralla G; Cruz L J; Santos A D; Hillyard D R; Dykert J; Rivier J E; Gray W R; Imperial J; DelaCruz R G; Sporning A; Terlau H; West P J; Yoshikami D; Olivera B M
An O-glycosylated neuroexcitatory conus peptide.
Biochemistry 1998;37(46):16019-25.
1998: Luo S; Kulak J M; Cartier G E; Jacobsen R B; Yoshikami D; Olivera B M; McIntosh J M
alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(21):8571-9.
1998: England L J; Imperial J; Jacobsen R; Craig A G; Gulyas J; Akhtar M; Rivier J; Julius D; Olivera B M
Inactivation of a serotonin-gated ion channel by a polypeptide toxin from marine snails.
Science (New York, N.Y.) 1998;281(5376):575-8.
1998: Shon K J; Olivera B M; Watkins M; Jacobsen R B; Gray W R; Floresca C Z; Cruz L J; Hillyard D R; Brink A; Terlau H; Yoshikami D
mu-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(12):4473-81.
1998: Jacobsen R; Jimenez E C; Grilley M; Watkins M; Hillyard D; Cruz L J; Olivera B M
The contryphans, a D-tryptophan-containing family of Conus peptides: interconversion between conformers.
The journal of peptide research : official journal of the American Peptide Society 1998;51(3):173-9.
1998: Bandyopadhyay P K; Colledge C J; Walker C S; Zhou L M; Hillyard D R; Olivera B M
Conantokin-G precursor and its role in gamma-carboxylation by a vitamin K-dependent carboxylase from a Conus snail.
The Journal of biological chemistry 1998;273(10):5447-50.
1998: Mitchell S S; Shon K J; Foster M P; Davis D R; Olivera B M; Ireland C M
Three-dimensional solution structure of conotoxin psi-PIIIE, an acetylcholine gated ion channel antagonist.
Biochemistry 1998;37(5):1215-20.
1998: Shon K J; Stocker M; Terlau H; Stühmer W; Jacobsen R; Walker C; Grilley M; Watkins M; Hillyard D R; Gray W R; Olivera B M
kappa-Conotoxin PVIIA is a peptide inhibiting the shaker K+ channel.
The Journal of biological chemistry 1998;273(1):33-8.
1997: Shon K J; Koerber S C; Rivier J E; Olivera B M; McIntosh J M
Three-dimensional solution structure of alpha-conotoxin MII, an alpha3beta2 neuronal nicotinic acetylcholine receptor-targeted ligand.
Biochemistry 1997;36(50):15693-700.
1997: Olivera B M
E.E. Just Lecture, 1996. Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacology.
Molecular biology of the cell 1997;8(11):2101-9.
1997: Jacobsen R; Yoshikami D; Ellison M; Martinez J; Gray W R; Cartier G E; Shon K J; Groebe D R; Abramson S N; Olivera B M; McIntosh J M
Differential targeting of nicotinic acetylcholine receptors by novel alphaA-conotoxins.
The Journal of biological chemistry 1997;272(36):22531-7.
1997: Shon K J; Grilley M; Jacobsen R; Cartier G E; Hopkins C; Gray W R; Watkins M; Hillyard D R; Rivier J; Torres J; Yoshikami D; Olivera B M
A noncompetitive peptide inhibitor of the nicotinic acetylcholine receptor from Conus purpurascens venom.
Biochemistry 1997;36(31):9581-7.
1997: Kulak J M; Nguyen T A; Olivera B M; McIntosh J M
Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5263-70.
1997: Tavazoie S F; Tavazoie M F; McIntosh J M; Olivera B M; Yoshikami D
Differential block of nicotinic synapses on B versus C neurones in sympathetic ganglia of frog by alpha-conotoxins MII and ImI.
British journal of pharmacology 1997;120(6):995-1000.
1997: Han K H; Hwang K J; Kim S M; Kim S K; Gray W R; Olivera B M; Rivier J; Shon K J
NMR structure determination of a novel conotoxin, [Pro 7,13] alpha A-conotoxin PIVA.
Biochemistry 1997;36(7):1669-77.
1997: Jimenez E C; Craig A G; Watkins M; Hillyard D R; Gray W R; Gulyas J; Rivier J E; Cruz L J; Olivera B M
Bromocontryphan: post-translational bromination of tryptophan.
Biochemistry 1997;36(5):989-94.
1997: Craig A G; Jimenez E C; Dykert J; Nielsen D B; Gulyas J; Abogadie F C; Porter J; Rivier J E; Cruz L J; Olivera B M; McIntosh J M
A novel post-translational modification involving bromination of tryptophan. Identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venom.
The Journal of biological chemistry 1997;272(8):4689-98.
1996: Jimenéz E C; Olivera B M; Gray W R; Cruz L J
Contryphan is a D-tryptophan-containing Conus peptide.
The Journal of biological chemistry 1996;271(45):28002-5.
1996: Terlau H; Stocker M; Shon K J; McIntosh J M; Olivera B M
MicroO-conotoxin MrVIA inhibits mammalian sodium channels, but not through site I.
Journal of neurophysiology 1996;76(3):1423-9.
1996: Terlau H; Shon K J; Grilley M; Stocker M; Stühmer W; Olivera B M
Strategy for rapid immobilization of prey by a fish-hunting marine snail.
Nature 1996;381(6578):148-51.
1996: Cartier G E; Yoshikami D; Gray W R; Luo S; Olivera B M; McIntosh J M
A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors.
The Journal of biological chemistry 1996;271(13):7522-8.
1995: Martinez J S; Olivera B M; Gray W R; Craig A G; Groebe D R; Abramson S N; McIntosh J M
alpha-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity.
Biochemistry 1995;34(44):14519-26.
1995: Olivera B M; Hillyard D R; Marsh M; Yoshikami D
Combinatorial peptide libraries in drug design: lessons from venomous cone snails.
Trends in biotechnology 1995;13(10):422-6.
1995: Hopkins C; Grilley M; Miller C; Shon K J; Cruz L J; Gray W R; Dykert J; Rivier J; Yoshikami D; Olivera B M
A new family of Conus peptides targeted to the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1995;270(38):22361-7.
1995: McIntosh J M; Hasson A; Spira M E; Gray W R; Li W; Marsh M; Hillyard D R; Olivera B M
A new family of conotoxins that blocks voltage-gated sodium channels.
The Journal of biological chemistry 1995;270(28):16796-802.
1995: Shon K J; Grilley M M; Marsh M; Yoshikami D; Hall A R; Kurz B; Gray W R; Imperial J S; Hillyard D R; Olivera B M
Purification, characterization, synthesis, and cloning of the lockjaw peptide from Conus purpurascens venom.
Biochemistry 1995;34(15):4913-8.
1995: Hasson A; Shon K J; Olivera B M; Spira M E
Alterations of voltage-activated sodium current by a novel conotoxin from the venom of Conus gloriamaris.
Journal of neurophysiology 1995;73(3):1295-301.
1995: McIntosh J M; Ghomashchi F; Gelb M H; Dooley D J; Stoehr S J; Giordani A B; Naisbitt S R; Olivera B M
Conodipine-M, a novel phospholipase A2 isolated from the venom of the marine snail Conus magus.
The Journal of biological chemistry 1995;270(8):3518-26.
1994: Shon K J; Hasson A; Spira M E; Cruz L J; Gray W R; Olivera B M
Delta-conotoxin GmVIA, a novel peptide from the venom of Conus gloriamaris.
Biochemistry 1994;33(38):11420-5.
1994: Filloux F; Karras J; Imperial J S; Gray W R; Olivera B M
The distribution of omega-conotoxin MVIICnle-binding sites in rat brain measured by autoradiography.
Neuroscience letters 1994;178(2):263-6.
1994: McIntosh J M; Yoshikami D; Mahe E; Nielsen D B; Rivier J E; Gray W R; Olivera B M
A nicotinic acetylcholine receptor ligand of unique specificity, alpha-conotoxin ImI.
The Journal of biological chemistry 1994;269(24):16733-9.
1994: Filloux F; Schapper A; Naisbitt S R; Olivera B M; McIntosh J M
Complex patterns of [125I]omega-conotoxin GVIA binding site expression during postnatal rat brain development.
Brain research. Developmental brain research 1994;78(1):131-6.
1994: Olivera B M; Miljanich G P; Ramachandran J; Adams M E
Calcium channel diversity and neurotransmitter release: the omega-conotoxins and omega-agatoxins.
Annual review of biochemistry 1994;63():823-67.
1993: McIntosh J M; Foderaro T A; Li W; Ireland C M; Olivera B M
Presence of serotonin in the venom of Conus imperialis.
Toxicon : official journal of the International Society on Toxinology 1993;31(12):1561-6.
1993: Haack J A; Kinser P; Yoshikami D; Olivera B M
Biotinylated derivatives of omega-conotoxins GVIA and MVIID: probes for neuronal calcium channels.
Neuropharmacology 1993;32(11):1151-9.
1993: Monje V D; Haack J A; Naisbitt S R; Miljanich G; Ramachandran J; Nasdasdi L; Olivera B M; Hillyard D R; Gray W R
A new Conus peptide ligand for Ca channel subtypes.
Neuropharmacology 1993;32(11):1141-9.
1993: Haack J A; Parks T N; Olivera B M
Conantokin-G antagonism of the NMDA receptor subtype expressed in cultured cerebellar granule cells.
Neuroscience letters 1993;163(1):63-6.
1993: Albensi B C; Ryujin K T; McIntosh J M; Naisbitt S R; Olivera B M; Fillous F
Localization of [125I]omega-conotoxin GVIA binding in human hippocampus and cerebellum.
Neuroreport 1993;4(12):1331-4.
1992: McIntosh J M; Adams M E; Olivera B M; Filloux F
Autoradiographic localization of the binding of calcium channel antagonist, [125I]omega-agatoxin IIIA, in rat brain.
Brain research 1992;594(1):109-14.
1992: Ramilo C A; Zafaralla G C; Nadasdi L; Hammerland L G; Yoshikami D; Gray W R; Kristipati R; Ramachandran J; Miljanich G; Olivera B M
Novel alpha- and omega-conotoxins from Conus striatus venom.
Biochemistry 1992;31(41):9919-26.
1992: Santos A D; Imperial J S; Chaudhary T; Beavis R C; Chait B T; Hunsperger J P; Olivera B M; Adams M E; Hillyard D R
Heterodimeric structure of the spider toxin omega-agatoxin IA revealed by precursor analysis and mass spectrometry.
The Journal of biological chemistry 1992;267(29):20701-5.
1992: Hammerland L G; Olivera B M; Yoshikami D
Conantokin-G selectively inhibits N-methyl-D-aspartate-induced currents in Xenopus oocytes injected with mouse brain mRNA.
European journal of pharmacology 1992;226(3):239-44.
1991: Olivera B M; Rivier J; Scott J K; Hillyard D R; Cruz L J
Conotoxins.
The Journal of biological chemistry 1991;266(33):22067-70.
1991: Myers R A; Zafaralla G C; Gray W R; Abbott J; Cruz L J; Olivera B M
alpha-Conotoxins, small peptide probes of nicotinic acetylcholine receptors.
Biochemistry 1991;30(38):9370-7.
1991: Zhu N; Olivera B M; Roth J R
Activity of the nicotinamide mononucleotide transport system is regulated in Salmonella typhimurium.
Journal of bacteriology 1991;173(3):1311-20.
1991: Olivera B M; Imperial J S; Cruz L J; Bindokas V P; Venema V J; Adams M E
Calcium channel-targeted polypeptide toxins.
Annals of the New York Academy of Sciences 1991;635():114-22.
1990: Mena E E; Gullak M F; Pagnozzi M J; Richter K E; Rivier J; Cruz L J; Olivera B M
Conantokin-G: a novel peptide antagonist to the N-methyl-D-aspartic acid (NMDA) receptor.
Neuroscience letters 1990;118(2):241-4.
1990: Olivera B M; Rivier J; Clark C; Ramilo C A; Corpuz G P; Abogadie F C; Mena E E; Woodward S R; Hillyard D R; Cruz L J
Diversity of Conus neuropeptides.
Science (New York, N.Y.) 1990;249(4966):257-63.
1990: Haack J A; Rivier J; Parks T N; Mena E E; Cruz L J; Olivera B M
Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity.
The Journal of biological chemistry 1990;265(11):6025-9.
1990: Woodward S R; Cruz L J; Olivera B M; Hillyard D R
Constant and hypervariable regions in conotoxin propeptides.
The EMBO journal 1990;9(4):1015-20.
1989: Zhu N; Olivera B M; Roth J R
Genetic characterization of the pnuC gene, which encodes a component of the nicotinamide mononucleotide transport system in Salmonella typhimurium.
Journal of bacteriology 1989;171(8):4402-9.
1989: Park U E; Olivera B M; Hughes K T; Roth J R; Hillyard D R
DNA ligase and the pyridine nucleotide cycle in Salmonella typhimurium.
Journal of bacteriology 1989;171(4):2173-80.
1989: Cruz L J; Kupryszewski G; LeCheminant G W; Gray W R; Olivera B M; Rivier J
mu-conotoxin GIIIA, a peptide ligand for muscle sodium channels: chemical synthesis, radiolabeling, and receptor characterization.
Biochemistry 1989;28(8):3437-42.
1989: Hillyard D R; Olivera B M; Woodward S; Corpuz G P; Gray W R; Ramilo C A; Cruz L J
A molluscivorous Conus toxin: conserved frameworks in conotoxins.
Biochemistry 1989;28(1):358-61.
1989: Yoshikami D; Bagabaldo Z; Olivera B M
The inhibitory effects of omega-conotoxins on Ca channels and synapses.
Annals of the New York Academy of Sciences 1989;560():230-48.
1988: Zafaralla G C; Ramilo C; Gray W R; Karlstrom R; Olivera B M; Cruz L J
Phylogenetic specificity of cholinergic ligands: alpha-conotoxin SI.
Biochemistry 1988;27(18):7102-5.
1988: Park U E; Roth J R; Olivera B M
Salmonella typhimurium mutants lacking NAD pyrophosphatase.
Journal of bacteriology 1988;170(8):3725-30.
1988: Hughes K T; Olivera B M; Roth J R
Structural gene for NAD synthetase in Salmonella typhimurium.
Journal of bacteriology 1988;170(5):2113-20.
1988: Zhu N; Olivera B M; Roth J R
Identification of a repressor gene involved in the regulation of NAD de novo biosynthesis in Salmonella typhimurium.
Journal of bacteriology 1988;170(1):117-25.
1988: Kerr L M; Filloux F; Olivera B M; Jackson H; Wamsley J K
Autoradiographic localization of calcium channels with [125I]omega-conotoxin in rat brain.
European journal of pharmacology 1988;146(1):181-3.
1988: Hirning L D; Fox A P; McCleskey E W; Olivera B M; Thayer S A; Miller R J; Tsien R W
Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons.
Science (New York, N.Y.) 1988;239(4835):57-61.
1988: Gray W R; Olivera B M; Cruz L J
Peptide toxins from venomous Conus snails.
Annual review of biochemistry 1988;57():665-700.
1987: Rivier J; Galyean R; Simon L; Cruz L J; Olivera B M; Gray W R
Total synthesis and further characterization of the gamma-carboxyglutamate-containing "sleeper" peptide from Conus geographus venom.
Biochemistry 1987;26(26):8508-12.
1987: Cruz L J; de Santos V; Zafaralla G C; Ramilo C A; Zeikus R; Gray W R; Olivera B M
Invertebrate vasopressin/oxytocin homologs. Characterization of peptides from Conus geographus and Conus straitus venoms.
The Journal of biological chemistry 1987;262(33):15821-4.
1987: McCleskey E W; Fox A P; Feldman D H; Cruz L J; Olivera B M; Tsien R W; Yoshikami D
Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(12):4327-31.
1987: Olivera B M; Cruz L J; de Santos V; LeCheminant G W; Griffin D; Zeikus R; McIntosh J M; Galyean R; Varga J; Gray W R
Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using omega-conotoxin from Conus magus venom.
Biochemistry 1987;26(8):2086-90.
1987: Feldman D H; Olivera B M; Yoshikami D
Omega Conus geographus toxin: a peptide that blocks calcium channels.
FEBS letters 1987;214(2):295-300.
1987: Rivier J; Galyean R; Gray W R; Azimi-Zonooz A; McIntosh J M; Cruz L J; Olivera B M
Neuronal calcium channel inhibitors. Synthesis of omega-conotoxin GVIA and effects on 45Ca uptake by synaptosomes.
The Journal of biological chemistry 1987;262(3):1194-8.
1985: Olivera B M; Gray W R; Zeikus R; McIntosh J M; Varga J; Rivier J; de Santos V; Cruz L J
Peptide neurotoxins from fish-hunting cone snails.
Science (New York, N.Y.) 1985;230(4732):1338-43.
1985: Cruz L J; Gray W R; Olivera B M; Zeikus R D; Kerr L; Yoshikami D; Moczydlowski E
Conus geographus toxins that discriminate between neuronal and muscle sodium channels.
The Journal of biological chemistry 1985;260(16):9280-8.
1984: Gray W R; Luque F A; Galyean R; Atherton E; Sheppard R C; Stone B L; Reyes A; Alford J; McIntosh M; Olivera B M
Conotoxin GI: disulfide bridges, synthesis, and preparation of iodinated derivatives.
Biochemistry 1984;23(12):2796-802.
1983: Gray W R; Rivier J E; Galyean R; Cruz L J; Olivera B M
Conotoxin MI. Disulfide bonding and conformational states.
The Journal of biological chemistry 1983;258(20):12247-51.
1981: Hillyard D; Rechsteiner M; Manlapaz-Ramos P; Imperial J S; Cruz L J; Olivera B M
The pyridine nucleotide cycle. Studies in Escherichia coli and the human cell line D98/AH2.
The Journal of biological chemistry 1981;256(16):8491-7.

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